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Francesco Epifano

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Publications

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Juliana Santos; Annie Marquis; Massimo Curini; Francesco Epifano; Salvatore Genovese; Daniel Grenier
Collinin Reduces Porphyromonas gingivalis Growth and Collagenase Activity and Inhibits the Lipopolysaccharide-Induced Macrophage Inflammatory Response and Osteoclast Differentiation and Function.
Francesco Epifano; Maria Carla Marcotullio; Rebecca Miller; Adhip P N Majumdar
Auraptene and its effects on the re-emergence of colon cancer stem cells.
Laura mercolini; Michele Protti; Vittorio Sorella; Massimo Curini; Francesco Epifano; Anna Ferranti; Roberto Mandrioli; Maria Augusta Raggi
Quantitative evaluation of auraptene and umbelliferone, chemopreventive coumarins in citrus fruits, by HPLC-UV-FL-MS.

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All Publications

2013: Juliana Santos; Annie Marquis; Massimo Curini; Francesco Epifano; Salvatore Genovese; Daniel Grenier
Collinin Reduces Porphyromonas gingivalis Growth and Collagenase Activity and Inhibits the Lipopolysaccharide-Induced Macrophage Inflammatory Response and Osteoclast Differentiation and Function.
Journal of periodontology 2013;84(5):704-11.
2013: Francesco Epifano; Maria Carla Marcotullio; Rebecca Miller; Adhip P N Majumdar
Auraptene and its effects on the re-emergence of colon cancer stem cells.
Phytotherapy research : PTR 2013;27(5):784-6.
2013: Laura mercolini; Michele Protti; Vittorio Sorella; Massimo Curini; Francesco Epifano; Anna Ferranti; Roberto Mandrioli; Maria Augusta Raggi
Quantitative evaluation of auraptene and umbelliferone, chemopreventive coumarins in citrus fruits, by HPLC-UV-FL-MS.
Journal of agricultural and food chemistry 2013;61(8):1694-701.
2013: Ivan Kosalec; D Kremer; M Locatelli; M Randić; Giuseppe Carlucci; Francesco Epifano; S Genovese; M Zovko Končić
Anthraquinone profile, antioxidant and antimicrobial activity of bark extracts of Rhamnus alaternus, R. fallax, R. intermedia and R. pumila.
Food chemistry 2013;136(2):335-41.
2012: laetitia bonifait; Francesco Epifano; Salvatore Genovese; Annie Marquis; Daniel Grenier
Synthesis and antimicrobial activity of geranyloxy- and farnesyloxy-acetophenone derivatives against oral pathogens.
Fitoterapia 2012;83(6):996-9.
2012: Francesco Epifano; Salvatore Genovese; Dario Kremer; Giuseppe Carlucci; Marco Randic; Marcello Locatelli
Re-investigation of the anthraquinone pool of Rhamnus spp.: madagascin from the fruits of Rhamnus cathartica and R. intermedia.
Natural product communications 2012;7(8):1029-32.
2012: Francesco Epifano; Salvatore Genovese; E James Squires; Matthew A Gray
Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist.
Bioorganic & medicinal chemistry letters 2012;22(9):3130-5.
2012: Marcello Locatelli; Marko Randic; Giuseppe Carlucci; Salvatore Genovese; Dario Kremer; Francesco Epifano
Development and application of high-performance liquid chromatography for the study of two new oxyprenylated anthraquinones produced by Rhamnus species.
Journal of chromatography. A 2012;1225():113-20.
2012: Elio Cenci; Francesco Epifano; Federica Messina; Elisabetta Rossi; Maria Carla Marcotullio
Antiviral furanosesquiterpenes from Commiphora erythraea.
Natural product communications 2012;7(2):143-4.
2012: Annie Marquis; Francesco Epifano; Salvatore Genovese; Daniel Grenier
The plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease.
BMC complementary and alternative medicine 2012;12():80.
2011: Federica Pellati; Stefania Benvenuti; Alessandro Bertaccini; Davide Bertelli; Lisa Cavicchi; Nicoletta Contaldo; Massimo Curini; Francesco Epifano; Salvatore Genovese; Giulia Orlandini; Maria Grazia Bellardi
Chromatographic methods for metabolite profiling of virus- and phytoplasma-infected plants of Echinacea purpurea.
Journal of agricultural and food chemistry 2011;59(19):10425-34.
2011: Salvatore Genovese; Paolo Gresele; Teresa Corazzi; Massimo Curini; Francesco Epifano
Inhibition of COX-1 activity and COX-2 expression by 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its semi-synthetic derivatives.
Bioorganic & medicinal chemistry letters 2011;21(19):5995-8.
2011: Marcello Locatelli; Giuseppe Carlucci; Francesco Epifano; Salvatore Genovese; Marijana Zovko Koncić; Ivan Kosalec; Dario Kremer
Anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of Rhamnus catharticus and R. orbiculatus.
Natural product communications 2011;6(9):1275-80.
2011: Céline Bruyère; Massimo Curini; Salvatore Genovese; Alexandra Ionescu-Motatu; Robert Kiss; Benjamin Lallemand; Francesco Epifano
Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines.
Bioorganic & medicinal chemistry letters 2011;21(14):4174-9.
2011: S Genovese; Francesco Epifano; Massimo Curini; D Menger; N C L Zembruski; J Weiss
In vitro effects of natural prenyloxycinnamic acids on human cytochrome P450 isozyme activity and expression.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2011;18(7):586-91.
2011: Céline Messier; Francesco Epifano; Salvatore Genovese; Daniel Grenier
Inhibition of Candida albicans biofilm formation and yeast-hyphal transition by 4-hydroxycordoin.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2011;18(5):380-3.
2011: Francesco Epifano
Natural products triggering biological targets.
Current drug targets 2011;12(3):287.
2011: Salvatore Genovese; Francesco Epifano
Auraptene: a natural biologically active compound with multiple targets.
Current drug targets 2011;12(3):381-6.
2011: Mark Feldman; Shinichi Tanabe; Francesco Epifano; Salvatore Genovese; Massimo Curini; Daniel Grenier
Antibacterial and anti-inflammatory activities of 4-hydroxycordoin: potential therapeutic benefits.
Journal of natural products 2011;74(1):26-31.
2011: Francesco Epifano; Silvio Sosa; Aurelia Tubaro; Maria Carla Marcotullio; Massimo Curini; Maria Carla Marcotullio
Topical anti-inflammatory activity of boropinic acid and its natural and semi-synthetic derivatives.
Bioorganic & medicinal chemistry letters 2011;21(2):769-72.
2010: Luigi Menghini; Francesco Epifano; Maria Carla Marcotullio; Maria Carla Marcotullio; Silvio Sosa; Aurelia Tubaro
Antiinflammatory activity of coumarins from Ligusticum lucidum Mill. subsp. cuneifolium (Guss.) Tammaro (Apiaceae).
Phytotherapy research : PTR 2010;24(11):1697-9.
2010: Vu Dang La; Francesco Lazzarin; Donata Ricci; Daniele Fraternale; Salvatore Genovese; Francesco Epifano; Daniel Grenier
Active principles of Grindelia robusta exert antiinflammatory properties in a macrophage model.
Phytotherapy research : PTR 2010;24(11):1687-92.
2010: S Genovese; Francesco Epifano; Giuseppe Carlucci; Maria Carla Marcotullio; Massimo Curini; M Locatelli
Quantification of 4'-geranyloxyferulic acid, a new natural colon cancer chemopreventive agent, by HPLC-DAD in grapefruit skin extract.
Journal of pharmaceutical and biomedical analysis 2010;53(2):212-4.
2010: S Genovese; F Tammaro; Luigi Menghini; G Carlucci; Francesco Epifano; M Locatelli
Comparison of three different extraction methods and HPLC determination of the anthraquinones aloe-emodine, emodine, rheine, chrysophanol and physcione in the bark of Rhamnus alpinus L. (Rhamnaceae).
Phytochemical analysis : PCA 2010;21(3):261-7.
2010: Luigi Menghini; Salvatore Genovese; Francesco Epifano; B Tirillini; C Ferrante; L Leporini
Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation.
International journal of immunopathology and pharmacology 2010;23(2):601-10.
2010: Salvatore Genovese; Jennifer E Foreman; Michael G Borland; Francesco Epifano; Frank J Gonzalez; Massimo Curini; Jeffrey M Peters
A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Life sciences 2010;86(13-14):493-8.
2010: Takuji Tanaka; Mariangela B M de Azevedo; Nelson Durán; Joel B Alderete; Francesco Epifano; Salvatore Genovese; Mayu Tanaka; Takahiro Tanaka; Massimo Curini
Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4'-geranyloxyferulic acid.
International journal of cancer. Journal international du cancer 2010;126(4):830-40.
2010: Luigi Menghini; Lidia Leporini; Bruno Tirillini; Francesco Epifano; Salvatore Genovese
Chemical composition and inhibitory activity against Helicobacter pylori of the essential oil of Apium nodiflorum (Apiaceae).
Journal of medicinal food 2010;13(1):228-30.
2009: Francesco Epifano; Caroline Pelucchini; Massimo Curini; Salvatore Genovese
Insights on novel biologically active natural products: 7-isopentenyloxycoumarin.
Natural product communications 2009;4(12):1755-60.
2009: Francesco Epifano; Massimo Curini; Luigi Menghini; Salvatore Genovese
Natural coumarins as a novel class of neuroprotective agents.
Mini reviews in medicinal chemistry 2009;9(11):1262-71.
2009: Salvatore Genovese; Francesco Epifano; Massimo Curini; Monika Dudra-Jastrzebska; Karolina Stepien
Prenyloxyphenylpropanoids as a novel class of anticonvulsive agents.
Bioorganic & medicinal chemistry letters 2009;19(18):5419-22.
2009: Salvatore Genovese; Massimo Curini; Francesco Epifano
Chemistry and biological activity of azoprenylated secondary metabolites.
Phytochemistry 2009;70(9):1082-91.
2008: Francesco Epifano; Gemma Molinaro; Salvatore Genovese; Richard Teke Ngomba; Ferdinando Nicoletti; Massimo Curini
Neuroprotective effect of prenyloxycoumarins from edible vegetables.
Neuroscience letters 2008;443(2):57-60.
2008: Francesco Epifano; Maria Carla Marcotullio; Maria Carla Marcotullio; Massimo Curini
Chemistry and pharmacology of collinin, active principle of Zanthoxylum spp.
Mini reviews in medicinal chemistry 2008;8(12):1203-8.
2008: Annalisa Chiavaroli; Vu Dang La; Giustino Orlando; Luigi Menghini; Francesco Epifano; Daniel Grenier
Rhamnus alpinus leaf extract suppresses lipopolysaccharide-induced, monocyte-derived macrophage chemokine secretion.
Inflammation 2008;31(5):313-8.
2008: Charles BODET; Francesco Epifano; Salvatore Genovese; Massimo Curini; Daniel Grenier
Effects of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its ester derivatives on biofilm formation by two oral pathogens, Porphyromonas gingivalis and Streptococcus mutans.
European journal of medicinal chemistry 2008;43(8):1612-20.
2008: Luigi Menghini; Francesco Epifano; Lidia Leporini; Rita Pagiotti; Bruno Tirillini
Phytochemical investigation on leaf extract of Cordia salicifolia Cham.
Journal of medicinal food 2008;11(1):193-4.
2008: Shingo Miyamoto; Francesco Epifano; Massimo Curini; Salvatore Genovese; Mihye Kim; Rikako Ishigamori-Suzuki; Yumiko Yasui; Shigeyuki Sugie; Takuji Tanaka
A novel prodrug of 4'-geranyloxy-ferulic acid suppresses colitis-related colon carcinogenesis in mice.
Nutrition and cancer 2008;60(5):675-84.
2007: Francesco Epifano; Salvatore Genovese; Silvio Sosa; Aurelia Tubaro; Massimo Curini
Synthesis and anti-inflammatory activity of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its ester derivatives.
Bioorganic & medicinal chemistry letters 2007;17(20):5709-14.
2007: Francesco Epifano; Massimo Curini; Salvatore Genovese; Michelle A Blaskovich; Andrew Hamilton; Said M Sebti
Prenyloxyphenylpropanoids as novel lead compounds for the selective inhibition of geranylgeranyl transferase I.
Bioorganic & medicinal chemistry letters 2007;17(9):2639-42.
2007: Francesco Epifano; Salvatore Genovese; Luigi Menghini; Massimo Curini
Chemistry and pharmacology of oxyprenylated secondary plant metabolites.
Phytochemistry 2007;68(7):939-53.
2006: Massimo Curini; Francesco Epifano; Maria Carla Marcotullio; Maria Carla Marcotullio; Luigi Menghini
3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid: a novel promising cancer chemopreventive agent.
Anti-cancer agents in medicinal chemistry 2006;6(6):571-7.
2006: Francesco Epifano; Luigi Menghini; Rita Pagiotti; Paola Angelini; Salvatore Genovese; Massimo Curini
In vitro inhibitory activity of boropinic acid against Helicobacter pylori.
Bioorganic & medicinal chemistry letters 2006;16(21):5523-5.
2006: Hiroyuki Kohno; Rikako Suzuki; Massimo Curini; Francesco Epifano; Federica Maltese; Sylvia Prieto Gonzales; Takuji Tanaka
Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice.
International journal of cancer. Journal international du cancer 2006;118(12):2936-42.
2006: Massimo Curini; Francesco Epifano; Salvatore Genovese; Alessandro Menghini; Gianmario Altinier; Aurelia Tubaro; Luigi Menghini
Fatty acids profile and antiinflammatory activity of Nonea setosa R. et S.
Phytotherapy research : PTR 2006;20(5):422-3.
2006: Massimo Curini; Giancarlo Cravotto; Francesco Epifano; Giovanni Giannone
Chemistry and biological activity of natural and synthetic prenyloxycoumarins.
Current medicinal chemistry 2006;13(2):199-222.
2005: Massimo Curini; Francesco Epifano; Salvatore Genovese
Synthesis of a novel prodrug of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans-propenoic acid for colon delivery.
Bioorganic & medicinal chemistry letters 2005;15(22):5049-52.
2005: Donata Ricci; Daniele Fraternale; Laura Giamperi; Anahi Bucchini; Francesco Epifano; Giovanni Burini; Massimo Curini
Chemical composition, antimicrobial and antioxidant activity of the essential oil of Teucrium marum (Lamiaceae).
Journal of ethnopharmacology 2005;98(1-2):195-200.
2005: Massimo Curini; Francesco Epifano; Maria Carla Marcotullio; Maria Carla Marcotullio; Ornelio Rosati
Ytterbium triflate-promoted tandem one-pot oxidation-Cannizzaro reaction of aryl methyl ketones.
Organic letters 2005;7(7):1331-3.