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Laurie Erb

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Chemicals & Drugs

Physiology

Anatomy

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Cloning, Molecular

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Lucas T Woods; Josef M Batek; Jean M Camden; Laurie Erb; Michael J Petris; Gary A Weisman
P2X7 receptor activation induces inflammatory responses in salivary gland epithelium.
Gary A Weisman; Lucas T Woods; Laurie Erb; Cheikh I Seye
P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.
Gary A Weisman; Lucas T Woods; Deepa Ajit; Jean M Camden; Richard C Garrad; Troy S Peterson; Christina Thebeau; Laurie Erb
Neuroprotective roles of the P2Y(2) receptor.

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All Publications

2012: Lucas T Woods; Josef M Batek; Jean M Camden; Laurie Erb; Michael J Petris; Gary A Weisman
P2X7 receptor activation induces inflammatory responses in salivary gland epithelium.
American journal of physiology. Cell physiology 2012;303(7):C790-801.
2012: Gary A Weisman; Lucas T Woods; Laurie Erb; Cheikh I Seye
P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.
CNS & neurological disorders drug targets 2012;11(6):722-38.
2012: Gary A Weisman; Lucas T Woods; Deepa Ajit; Jean M Camden; Richard C Garrad; Troy S Peterson; Christina Thebeau; Laurie Erb
Neuroprotective roles of the P2Y(2) receptor.
Purinergic signalling 2012;8(3):559-78.
2012: Gary A Weisman; Lucas T Woods; Deepa Ajit; Jean M Camden; Troy S Peterson; Laurie Erb
P2 receptors for extracellular nucleotides in the central nervous system: role of P2X7 and P2Y₂ receptor interactions in neuroinflammation.
Molecular neurobiology 2012;46(1):96-113.
2012: Hye Jung Kim; Troy S Peterson; Michael J Petris; Grace Y Sun; Yanfang Wang; Deepa Ajit; Jean M Camden; Laurie Erb; W Gibson Wood; Gary A Weisman
Nucleotides released from Aβ₁₋₄₂ -treated microglial cells increase cell migration and Aβ₁₋₄₂ uptake through P2Y₂ receptor activation.
Journal of neurochemistry 2012;121(2):228-38.
2010: Troy S Peterson; Jean M Camden; Yanfang Wang; Cheikh I Seye; W Gibson Wood; Grace Y Sun; Laurie Erb; Michael J Petris; Gary A Weisman
P2Y2 nucleotide receptor-mediated responses in brain cells.
Molecular neurobiology 2010;41(2-3):356-66.
2010: Ann M Ratchford; Olga J Baker; Jean M Camden; Shivaji Rikka; Michael J Petris; Cheikh I Seye; Laurie Erb; Gary A Weisman
P2Y2 nucleotide receptors mediate metalloprotease-dependent phosphorylation of epidermal growth factor receptor and ErbB3 in human salivary gland cells.
The Journal of biological chemistry 2010;285(10):7545-55.
2009: Qiongman Kong; Troy S Peterson; Olga Baker; Emily Stanley; Jean M Camden; Cheikh I Seye; Laurie Erb; Agnes Simonyi; W Gibson Wood; Grace Y Sun; Gary A Weisman
Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor.
Journal of neurochemistry 2009;109(5):1300-10.
2008: Ningpu Yu; Laurie Erb; Rikka Shivaji; Gary A Weisman; Cheikh I Seye
Binding of the P2Y2 nucleotide receptor to filamin A regulates migration of vascular smooth muscle cells.
Circulation research 2008;102(5):581-8.
2007: Zhongji Liao; Cheikh I Seye; Gary A Weisman; Laurie Erb
The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.
Journal of cell science 2007;120(Pt 9):1654-62.
2007: Nataliya E Chorna; Migdalia Chevres; Cynthia Santos-Berrios; Elsie A Orellano; Laurie Erb; Fernando A González
P2Y2 receptors induced cell surface redistribution of alpha(v) integrin is required for activation of ERK 1/2 in U937 cells.
Journal of cellular physiology 2007;211(2):410-22.
2007: Cheikh I Seye; Qiongman Kong; Ningpu Yu; Fernando A Gonzalez; Laurie Erb; Gary A Weisman
P2 receptors in atherosclerosis and postangioplasty restenosis.
Purinergic signalling 2007;3(1-2):153-62.
2006: Cheikh I Seye; Qiongman Kong; Ningpu Yu; Fernando A Gonzalez; Laurie Erb; Gary A Weisman
P2 receptors in atherosclerosis and postangioplasty restenosis.
Purinergic signalling 2006;2(3):471-80.
2006: Laurie Erb; Zhongji Liao; Cheikh I Seye; Gary A Weisman
P2 receptors: intracellular signaling.
Pflügers Archiv : European journal of physiology 2006;452(5):552-62.
2006: Olga J Baker; Jean M Camden; Ann M Ratchford; Cheikh I Seye; Laurie Erb; Gary A Weisman
Differential coupling of the P2Y1 receptor to Galpha14 and Galphaq/11 proteins during the development of the rat salivary gland.
Archives of oral biology 2006;51(5):359-70.
2006: Gary A Weisman; Ningpu Yu; Zhongji Liao; Fernando Gonzaléz; Laurie Erb; Cheikh I Seye
P2 receptors in health and disease.
Biotechnology & genetic engineering reviews 2006;22():171-95.
2005: Qiongman Kong; Min Wang; Zhongji Liao; Jean M Camden; Sue Yu; Agnes Simonyi; Grace Y Sun; Fernando A Gonzalez; Laurie Erb; Cheikh I Seye; Gary A Weisman
P2X(7) nucleotide receptors mediate caspase-8/9/3-dependent apoptosis in rat primary cortical neurons.
Purinergic signalling 2005;1(4):337-47.
2005: Sriparna Bagchi; Zhongji Liao; Fernando A Gonzalez; Nataliya E Chorna; Cheikh I Seye; Gary A Weisman; Laurie Erb
The P2Y2 nucleotide receptor interacts with alphav integrins to activate Go and induce cell migration.
The Journal of biological chemistry 2005;280(47):39050-7.
2005: Min Wang; Qiongman Kong; Fernando A Gonzalez; Grace Sun; Laurie Erb; Cheikh I Seye; Gary A Weisman
P2Y nucleotide receptor interaction with alpha integrin mediates astrocyte migration.
Journal of neurochemistry 2005;95(3):630-40.
2005: Jean M Camden; Ann M Schrader; Ryan E Camden; Fernando A González; Laurie Erb; Cheikh I Seye; Gary A Weisman
P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing.
The Journal of biological chemistry 2005;280(19):18696-702.
2005: Elzbieta Kaczmarek; Laurie Erb; Katarzyna Koziak; Robert Jarzyna; Marcia R Wink; Olaf Guckelberger; J Krzysztof Blusztajn; Vickery Trinkaus-Randall; Gary A Weisman; Simon C Robson
Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways.
Thrombosis and haemostasis 2005;93(4):735-42.
2005: Gary A Weisman; M Wang; Qiongman Kong; Nataliya E Chorna; Joseph T Neary; Grace Y Sun; Fernando A González; Cheikh I Seye; Laurie Erb
Molecular determinants of P2Y2 nucleotide receptor function: implications for proliferative and inflammatory pathways in astrocytes.
Molecular neurobiology 2005;31(1-3):169-83.
2005: Fernando A González; Gary A Weisman; Laurie Erb; Cheikh I Seye; Grace Y Sun; Betty Velázquez; Melvin G Hernández-Pérez; Nataliya E Chorna
Mechanisms for inhibition of P2 receptors signaling in neural cells.
Molecular neurobiology 2005;31(1-3):65-79.
2004: Nataliya E Chorna; Laura I Santiago-Pérez; Laurie Erb; Cheikh I Seye; Joseph T Neary; Grace Y Sun; Gary A Weisman; Fernando A González
P2Y receptors activate neuroprotective mechanisms in astrocytic cells.
Journal of neurochemistry 2004;91(1):119-32.
2004: Cheikh I Seye; Ningpu Yu; Fernando A González; Laurie Erb; Gary A Weisman
The P2Y2 nucleotide receptor mediates vascular cell adhesion molecule-1 expression through interaction with VEGF receptor-2 (KDR/Flk-1).
The Journal of biological chemistry 2004;279(34):35679-86.
2004: Jun Liu; Zhongji Liao; Jean M Camden; Korey D Griffin; Richard C Garrad; Laura I Santiago-Pérez; Fernando A González; Cheikh I Seye; Gary A Weisman; Laurie Erb
Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors.
The Journal of biological chemistry 2004;279(9):8212-8.
2003: Cheikh I Seye; Ningpu Yu; Renu Jain; Qiongman Kong; Tess Minor; Jessica Newton; Laurie Erb; Fernando A González; Gary A Weisman
The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells.
The Journal of biological chemistry 2003;278(27):24960-5.
2002: Cheikh I Seye; Qiongman Kong; Laurie Erb; Richard C Garrad; Brent W Krugh; Meifang Wang; John T Turner; Michael Sturek; Fernando A González; Gary A Weisman
Functional P2Y2 nucleotide receptors mediate uridine 5'-triphosphate-induced intimal hyperplasia in collared rabbit carotid arteries.
Circulation 2002;106(21):2720-6.
2001: Laura I Santiago-Pérez; Rosa V Flores; C Santos-Berríos; Nataliya E Chorna; Brent W Krugh; Richard C Garrad; Laurie Erb; Gary A Weisman; Fernando A González
P2Y(2) nucleotide receptor signaling in human monocytic cells: activation, desensitization and coupling to mitogen-activated protein kinases.
Journal of cellular physiology 2001;187(2):196-208.
2001: Laurie Erb; Jun Liu; J Ockerhausen; Qiongman Kong; Richard C Garrad; K Griffin; C Neal; Brent W Krugh; Laura I Santiago-Pérez; Fernando A González; H D Gresham; John T Turner; Gary A Weisman
An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction.
The Journal of cell biology 2001;153(3):491-501.
2000: M Otero; Richard C Garrad; Betty Velázquez; Melvin G Hernández-Pérez; Jean M Camden; Laurie Erb; Lane L Clarke; John T Turner; Gary A Weisman; Fernando A González
Mechanisms of agonist-dependent and -independent desensitization of a recombinant P2Y2 nucleotide receptor.
Molecular and cellular biochemistry 2000;205(1-2):115-23.
1999: Gary A Weisman; Richard C Garrad; Laurie Erb; C Santos-Berrios; Fernando A Gonzalez
P2Y receptors in the nervous system: molecular studies of a P2Y2 receptor subtype from NG108-15 neuroblastoma x glioma hybrid cells.
Progress in brain research 1999;120():33-43.
1998: Richard C Garrad; M A Otero; Laurie Erb; Patty M Theiss; Lane L Clarke; Fernando A Gonzalez; John T Turner; Gary A Weisman
Structural basis of agonist-induced desensitization and sequestration of the P2Y2 nucleotide receptor. Consequences of truncation of the C terminus.
The Journal of biological chemistry 1998;273(45):29437-44.
1998: Gary A Weisman; Richard C Garrad; Laurie Erb; M Otero; Fernando A Gonzalez; Lane L Clarke
Structure and function of P2Y2 nucleotide receptors in cystic fibrosis (CF) epithelium.
Advances in experimental medicine and biology 1998;431():417-24.
1997: DM Sullivan; Laurie Erb; E Anglade; Gary A Weisman; John T Turner; Karl G Csaky
Identification and characterization of P2Y2 nucleotide receptors in human retinal pigment epithelial cells.
Journal of neuroscience research 1997;49(1):43-52.
1997: Masahiro Koshiba; Sergey Apasov; V Sverdlov; P Chen; Laurie Erb; John T Turner; G A Weisman; Michail V Sitkovsky
Transient up-regulation of P2Y2 nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(3):831-6.
1996: Steven J Charlton; C A Brown; Gary A Weisman; John T Turner; Laurie Erb; Michael R Boarder
Cloned and transfected P2Y4 receptors: characterization of a suramin and PPADS-insensitive response to UTP.
British journal of pharmacology 1996;119(7):1301-3.
1996: Steven J Charlton; C A Brown; Gary A Weisman; John T Turner; Laurie Erb; Michael R Boarder
PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors.
British journal of pharmacology 1996;118(3):704-10.
1996: KD Lustig; Gary A Weisman; J T Turner; Richard C Garrad; A K Shiau; Laurie Erb
P2U purinoceptors: cDNA cloning, signal transduction mechanisms and structure-function analysis.
Ciba Foundation symposium 1996;198():193-204; discussion 204-7.
1995: T Nguyen; Laurie Erb; Gary A Weisman; A Marchese; Hong-Qiang Heng; Richard C Garrad; Susan R George; John T Turner; Brian F O'Dowd
Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene.
The Journal of biological chemistry 1995;270(52):30845-8.
1995: Laurie Erb; Richard C Garrad; Y Wang; T Quinn; John T Turner; Gary A Weisman
Site-directed mutagenesis of P2U purinoceptors. Positively charged amino acids in transmembrane helices 6 and 7 affect agonist potency and specificity.
The Journal of biological chemistry 1995;270(9):4185-8.
1994: C E Parr; DM Sullivan; Anthony M Paradiso; Eduardo R Lazarowski; L H Burch; John C Olsen; Laurie Erb; Gary A Weisman; Richard C Boucher; John T Turner
Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):13067.
1994: Michael R Boarder; John T Turner; Laurie Erb; Gary A Weisman
Classification of P2 purinoceptors. Not all G protein-coupled P2 purinoceptors can be classed as P2Y.
Trends in pharmacological sciences 1994;15(8):280-1.
1994: C E Parr; DM Sullivan; Anthony M Paradiso; Eduardo R Lazarowski; L H Burch; John C Olsen; Laurie Erb; Gary A Weisman; Richard C Boucher; John T Turner
Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3275-9.
1993: Laurie Erb; KD Lustig; DM Sullivan; John T Turner; Gary A Weisman
Functional expression and photoaffinity labeling of a cloned P2U purinergic receptor.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10449-53.
1992: KD Lustig; M G Sportiello; Laurie Erb; Gary A Weisman
A nucleotide receptor in vascular endothelial cells is specifically activated by the fully ionized forms of ATP and UTP.
The Biochemical journal 1992;284 ( Pt 3)():733-9.
1992: KD Lustig; Laurie Erb; D M Landis; C S Hicks-Taylor; X Zhang; M G Sportiello; Gary A Weisman
Mechanisms by which extracellular ATP and UTP stimulate the release of prostacyclin from bovine pulmonary artery endothelial cells.
Biochimica et biophysica acta 1992;1134(1):61-72.
1990: Laurie Erb; KD Lustig; A H Ahmed; Fernando A Gonzalez; Gary A Weisman
Covalent incorporation of 3'-O-(4-benzoyl)benzoyl-ATP into a P2 purinoceptor in transformed mouse fibroblasts.
The Journal of biological chemistry 1990;265(13):7424-31.
1989: Fernando A Gonzalez; A H Ahmed; KD Lustig; Laurie Erb; Gary A Weisman
Permeabilization of transformed mouse fibroblasts by 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate and the desensitization of the process.
Journal of cellular physiology 1989;139(1):109-15.