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Philipp Erben

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Chemicals & Drugs

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Tumor Cell Line

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Christoph Aderhold; Richard Birk; Philipp Erben; Anne Faber; Ralf-Dieter Hofheinz; Karl Hormann; Alexander Sauter; Jörg Ulrich Sommer; Jens Stern-Straeter; Claudia Umbreit; Johannes David Schultz
Chemotherapeutic Alteration of VEGF, PDGF and PDGFRα/β Expression Under 5-FU vs. Docetaxel in HPV-transformed Squamous Cell Carcinoma Compared To HPV-negative HNSCC In Vitro.
Eva Lengfelder; Carsten Müller-Tidow; Cristina Sauerland; Stephanie Schneider; Susanne Schnittger; Beate Schultheis; Hubert Serve; Karsten Spiekermann; Bernhard Wörmann; Carlo Aul; Wolfgang E Berdel; Jan Braess; Thomas Büchner; Philipp Erben; Claudia Haferlach; Torsten Haferlach; Benjamin Hanfstein; Rüdiger Hehlmann; Achim Heinecke; Wolfgang Hiddemann; Wolf-Karsten Hofmann; Heinz A Horst; Karl-Anton Kreuzer; Utz Krug
Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group.
Juliana Schwaab; Philipp Ströbel; Jenny Rinke; Susanne Schnittger; Nicholas C P Cross; Philipp Erben; Thomas Ernst; Torsten Haferlach; Andreas Hochhaus; Wolf-Karsten Hofmann; Georgia Metzgeroth; Max Mossner; Andreas Reiter
Activating CBL mutations are associated with a distinct MDS/MPN phenotype.

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All Publications

2013: Christoph Aderhold; Richard Birk; Philipp Erben; Anne Faber; Ralf-Dieter Hofheinz; Karl Hormann; Alexander Sauter; Jörg Ulrich Sommer; Jens Stern-Straeter; Claudia Umbreit; Johannes David Schultz
Chemotherapeutic Alteration of VEGF, PDGF and PDGFRα/β Expression Under 5-FU vs. Docetaxel in HPV-transformed Squamous Cell Carcinoma Compared To HPV-negative HNSCC In Vitro.
Anticancer research 2013;33(5):1951-61.
2013: Eva Lengfelder; Carsten Müller-Tidow; Cristina Sauerland; Stephanie Schneider; Susanne Schnittger; Beate Schultheis; Hubert Serve; Karsten Spiekermann; Bernhard Wörmann; Carlo Aul; Wolfgang E Berdel; Jan Braess; Thomas Büchner; Philipp Erben; Claudia Haferlach; Torsten Haferlach; Benjamin Hanfstein; Rüdiger Hehlmann; Achim Heinecke; Wolfgang Hiddemann; Wolf-Karsten Hofmann; Heinz A Horst; Karl-Anton Kreuzer; Utz Krug
Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group.
Annals of hematology 2013;92(1):41-52.
2012: Juliana Schwaab; Philipp Ströbel; Jenny Rinke; Susanne Schnittger; Nicholas C P Cross; Philipp Erben; Thomas Ernst; Torsten Haferlach; Andreas Hochhaus; Wolf-Karsten Hofmann; Georgia Metzgeroth; Max Mossner; Andreas Reiter
Activating CBL mutations are associated with a distinct MDS/MPN phenotype.
Annals of hematology 2012;91(11):1713-20.
2012: Daniel Nowak; Verena Nowak; Julia Oblaender; Seishi Ogawa; Andreas Reiter; Susanne Saussele; Brigitte Schlegelberger; Wolfgang Seifarth; Christel Weiss; Jan Braess; Thomas Buechner; Philipp Erben; Alice Fabarius; Claudia Haferlach; Benjamin Hanfstein; Anna Hecht; Wolf-Karsten Hofmann; Gero Hütter; Marion Klaumuenzer; Alexander Kohlmann; Maximilian Mossner; Martin C Müller; Florian Nolte; Eva Lengfelder
SNP array analysis of acute promyelocytic leukemia may be of prognostic relevance and identifies a potential high risk group with recurrent deletions on chromosomal subband 1q31.3.
Genes, chromosomes & cancer 2012;51(8):756-67.
2012: Anne Faber; Sarah Hoedt; Karl Hoermann; Ralf-Dieter Hofheinz; Alexander Sauter; Ulrich Sommer; Jens Stern-Straeter; Philipp Erben; David Johannes Schultz
Alteration of MMP-2 and -14 expression by imatinib in HPV-positive and -negative squamous cell carcinoma.
Oncology reports 2012;28(1):172-8.
2012: T Klag; Philipp Erben; N Härtel; Andreas Hochhaus; T Schenk; U Schnetzke; J Schwaab; Paul La Rosée
Omacetaxine mepesuccinate prevents cytokine-dependent resistance to nilotinib in vitro: potential role of the common β-subunit c of cytokine receptors.
Leukemia 2012;26(6):1321-8.
2012: Nicolai Härtel; Andreas Hochhaus; Thomas Klag; Philipp Erben; Benjamin Hanfstein; Martin C Mueller; Thomas Schenk; Paul La Rosée
Enhanced ABL-inhibitor-induced MAPK-activation in T315I-BCR-ABL-expressing cells: a potential mechanism of altered leukemogenicity.
Journal of cancer research and clinical oncology 2012;138(2):203-12.
2012: Philipp Erben; Ralf-Dieter Hofheinz; Wolf-Karsten Hofmann; Peter Hohenberger; Daniel Nowak; Christian Sauer; Philipp Ströbel; Bernd Kasper
Molecular analysis of desmoid tumors with a high-density single-nucleotide polymorphism array identifies new molecular candidate lesions.
Onkologie 2012;35(11):684-9.
2012: Darko Gosenca; Wolf-Karsten Hofmann; Christine Leib-Mösch; Jens Mayer; Olivia Diem; Philipp Erben; Alice Fabarius; Ute Gabriel; Annette Steidler; Wolfgang Seifarth
HERV-E-mediated modulation of PLA2G4A transcription in urothelial carcinoma.
PloS one 2012;7(11):e49341.
2012: J D Schultz; J U Sommer; C Thorn; Philipp Erben; A Faber; S Hoedt; Ralf-Dieter Hofheinz; K Hörmann; A Sauter
Chemotherapeutic alteration of β-catenin and c-kit expression by imatinib in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro.
Oncology reports 2012;27(1):270-80.
2011: Philipp Erben; Benjamin Hanfstein; Andreas Hochhaus; Karoline Horisberger; Georg Kähler; Peter Kienle; Juliana Popa; Stefan Post; Philipp Ströbel; Frederik Wenz; Beatrice Bohn; Ralf-Dieter Hofheinz
KRAS and BRAF mutations and PTEN expression do not predict efficacy of cetuximab-based chemoradiotherapy in locally advanced rectal cancer.
International journal of radiation oncology, biology, physics 2011;81(4):1032-8.
2011: J D Schultz; J U Sommer; C Thorn; Philipp Erben; A Faber; Ralf-Dieter Hofheinz; K Hörmann; K Mühlheim; A Sauter
Chemotherapeutic alteration of VEGF-/PDGF- and PDGF-Rα/β expression by imatinib in HPV-transformed squamous cell carcinoma compared to HPV-negative HNSCC in vitro.
Oncology reports 2011;26(5):1099-109.
2011: Christoph Walz; Michael Ritter; Joannah Score; Nick Telford; Adrian Bloor; Nicholas C P Cross; Philipp Erben; Stefan Gesk; Claudia Haferlach; Torsten Haferlach; Andreas Hochhaus; Wolf-Karsten Hofmann; Georgia Metzgeroth; Andreas Reiter
Response of ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of FMS-like tyrosine kinase 3.
Blood 2011;118(8):2239-42.
2011: Georgia Metzgeroth; Eva-Maria Kanders; Philipp Erben; Wolf-Karsten Hofmann; Jan Hastka
The role of zinc protoporphyrin measurement in the differentiation between primary myelofibrosis and essential thrombocythaemia.
Annals of hematology 2011;90(4):389-94.
2011: Juliana Schwaab; Philipp Ströbel; Frederik Wenz; Beatrice Bohn; Deniz Gencer; Ralf-Dieter Hofheinz; Wolf-Karsten Hofmann; Karoline Horisberger; Georg Kähler; Peter Kienle; Stefan Post; Philipp Erben
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
BMC cancer 2011;11():363.
2010: Karoline Horisberger; Philipp Erben; Philipp Ströbel; Beatrice Bohn; Melanie Hahn; Georg Kähler; Frederik Wenz; Andreas Hochhaus; Stefan Post; Frank Willeke; Ralf-Dieter Hofheinz
Annexin and survivin in locally advanced rectal cancer: indicators of resistance to preoperative chemoradiotherapy?
Onkologie 2010;33(8-9):439-44.
2009: Karoline Horisberger; Anne Treschl; Sabine Mai; Manuel Barreto-Miranda; Peter Kienle; Philipp Ströbel; Philipp Erben; Christoph Woernle; Dietmar Dinter; Georg Kähler; Andreas Hochhaus; Stefan Post; Frank Willeke; Frederik Wenz; Ralf-Dieter Hofheinz
Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a Phase II MARGIT trial.
International journal of radiation oncology, biology, physics 2009;74(5):1487-93.
2009: Karoline Horisberger; Philipp Erben; Benjamin Muessle; Christoph Woernle; Philipp Stroebel; Georg Kaehler; Frederik Wenz; Andreas Hochhaus; Stefan Post; Frank Willeke; Ralf-Dieter Hofheinz
Topoisomerase I expression correlates to response to neoadjuvant irinotecan-based chemoradiation in rectal cancer.
Anti-cancer drugs 2009;20(6):519-24.
2009: Christoph Walz; J Score; J Mix; D Cilloni; C Roche-Lestienne; R-F Yeh; J L Wiemels; E Ottaviani; Philipp Erben; Andreas Hochhaus; M Baccarani; D Grimwade; Claude Preudhomme; J Apperley; giovanni martinelli; Giuseppe Saglio; Nicholas C P Cross; Andreas Reiter
The molecular anatomy of the FIP1L1-PDGFRA fusion gene.
Leukemia 2009;23(2):271-8.
2008: Philipp Erben; Karoline Horisberger; Benjamin Muessle; Martin Christian Müller; Anne Treschl; Thomas Ernst; Georg Kähler; Philipp Ströbel; Frederik Wenz; Peter Kienle; Stefan Post; Andreas Hochhaus; Frank Willeke; Ralf-Dieter Hofheinz
mRNA expression of platelet-derived growth factor receptor-beta and C-KIT: correlation with pathologic response to cetuximab-based chemoradiotherapy in patients with rectal cancer.
International journal of radiation oncology, biology, physics 2008;72(5):1544-50.
2008: Georgia Metzgeroth; Christoph Walz; Philipp Erben; Helena Popp; Annette Schmitt-Graeff; Claudia Haferlach; Alice Fabarius; Susanne Schnittger; David Grimwade; Nicholas C P Cross; Rüdiger Hehlmann; Andreas Hochhaus; Andreas Reiter
Safety and efficacy of imatinib in chronic eosinophilic leukaemia and hypereosinophilic syndrome: a phase-II study.
British journal of haematology 2008;143(5):707-15.
2008: Thomas Ernst; Jana Hoffmann; Philipp Erben; Benjamin Hanfstein; Armin Leitner; Rüdiger Hehlmann; Andreas Hochhaus; Martin C Müller
ABL single nucleotide polymorphisms may masquerade as BCR-ABL mutations associated with resistance to tyrosine kinase inhibitors in patients with chronic myeloid leukemia.
Haematologica 2008;93(9):1389-93.
2008: Paul La Rosée; Susanne Holm-Eriksen; Heiko Konig; Nicolai Härtel; Thomas Ernst; Julia Debatin; Martin C Mueller; Philipp Erben; Anja Binckebanck; Lydia Wunderle; Yaping Shou; Margaret Dugan; Rüdiger Hehlmann; Oliver G Ottmann; Andreas Hochhaus
Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib.
Haematologica 2008;93(5):765-9.
2008: Thomas Ernst; Philipp Erben; Martin C Müller; Peter Paschka; Thomas Schenk; Jana Hoffmann; Sebastian Kreil; Paul La Rosée; Rüdiger Hehlmann; Andreas Hochhaus
Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib.
Haematologica 2008;93(2):186-92.
2008: Thomas Ernst; Jana Hoffmann; Philipp Erben; Rüdiger Hehlmann; Andreas Hochhaus; Martin C Müller
Suitability of the PAXgene system to stabilize bone marrow RNA in imatinib-resistant patients with chronic myeloid leukemia.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2008;46(3):318-22.
2008: Martin C Müller; Philipp Erben; Giuseppe Saglio; Enrico Gottardi; C G Nyvold; T Schenk; T Ernst; S Lauber; J Kruth; Rüdiger Hehlmann; Andreas Hochhaus
Harmonization of BCR-ABL mRNA quantification using a uniform multifunctional control plasmid in 37 international laboratories.
Leukemia 2008;22(1):96-102.
2007: Michelle Giehl; Alice Fabarius; Oliver Frank; Philipp Erben; Chun Zheng; M Hafner; Andreas Hochhaus; Rüdiger Hehlmann; Wolfgang Seifarth
Expression of the p210BCR-ABL oncoprotein drives centrosomal hypertrophy and clonal evolution in human U937 cells.
Leukemia 2007;21(9):1971-6.
2007: Alice Fabarius; Claudia Haferlach; Martin C Müller; Philipp Erben; Tanja Lahaye; Michelle Giehl; Oliver Frank; Wolfgang Seifarth; Rüdiger Hehlmann; Andreas Hochhaus
Dynamics of cytogenetic aberrations in Philadelphia chromosome positive and negative hematopoiesis during dasatinib therapy of chronic myeloid leukemia patients after imatinib failure.
Haematologica 2007;92(6):834-7.
2007: Georgia Metzgeroth; Christoph Walz; Joannah Score; R Siebert; S Schnittger; Claudia Haferlach; H Popp; Torsten Haferlach; Philipp Erben; J Mix; Martin C Müller; H Beneke; L Müller; F Del Valle; Walter Aulitzky; G Wittkowsky; Norbert Schmitz; C Schulte; K Müller-Hermelink; E Hodges; S J Whittaker; F Diecker; H Döhner; P Schuld; Rüdiger Hehlmann; Andreas Hochhaus; Nicholas C P Cross; Andreas Reiter
Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma.
Leukemia 2007;21(6):1183-8.
2007: Jelena V Jovanovic; Joannah Score; Katherine Waghorn; Daniela Cilloni; Enrico Gottardi; Georgia Metzgeroth; Philipp Erben; Helena Popp; Christoph Walz; Andreas Hochhaus; Catherine Roche-Lestienne; Claude Preudhomme; Ellen Solomon; Jane Apperley; Michela Rondoni; Emanuela Ottaviani; giovanni martinelli; Finella Brito-Babapulle; Giuseppe Saglio; Rüdiger Hehlmann; Nicholas C P Cross; Andreas Reiter; David Grimwade
Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.
Blood 2007;109(11):4635-40.
2007: Jorge Cortes; Philippe Rousselot; Dong-Wook Kim; Ellen Ritchie; Nelson Hamerschlak; Steven Coutre; Andreas Hochhaus; françois guilhot; Giuseppe Saglio; Jane Apperley; Oliver G Ottmann; Neil Shah; Philipp Erben; Susan Branford; Prasheen Agarwal; Ashwin Gollerkeri; Michele Baccarani
Dasatinib induces complete hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in blast crisis.
Blood 2007;109(8):3207-13.
2007: Georgia Metzgeroth; Dietmar Dinter; Philipp Erben; Paul La Rosée; Rüdiger Hehlmann; Jan Hastka
Systemic mastocytosis simulating osseous metastatic disease.
British journal of haematology 2007;136(1):1.
2006: Christoph Walz; Claire Curtis; Susanne Schnittger; Beate Schultheis; Georgia Metzgeroth; Claudia Schoch; Eva Lengfelder; Philipp Erben; Martin C Müller; Torsten Haferlach; Andreas Hochhaus; Rüdiger Hehlmann; Nicholas C P Cross; Andreas Reiter
Transient response to imatinib in a chronic eosinophilic leukemia associated with ins(9;4)(q33;q12q25) and a CDK5RAP2-PDGFRA fusion gene.
Genes, chromosomes & cancer 2006;45(10):950-6.