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Tommy Andersson

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Tommy Andersson; Carl Hampus Lyttkens
[Economic matching theory in renal transplantation. Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel 2012].
Cecilia Magnusson; Jian Liu; Roy Ehrnström; Jonas Manjer; Karin Jirström; Tommy Andersson; Anita Sjölander
Cysteinyl leukotriene receptor expression pattern affects migration of breast cancer cells and survival of breast cancer patients.
Veronika Jenei; Victoria Sherwood; Jill Howlin; Rickard Linnskog; Annette Säfholm; Lena Axelsson; Tommy Andersson
A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion.

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2012: Tommy Andersson; Carl Hampus Lyttkens
[Economic matching theory in renal transplantation. Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel 2012].
Läkartidningen 2012;109(49-50):2276-7.
2011: Cecilia Magnusson; Jian Liu; Roy Ehrnström; Jonas Manjer; Karin Jirström; Tommy Andersson; Anita Sjölander
Cysteinyl leukotriene receptor expression pattern affects migration of breast cancer cells and survival of breast cancer patients.
International journal of cancer. Journal international du cancer 2011;129(1):9-22.
2009: Veronika Jenei; Victoria Sherwood; Jill Howlin; Rickard Linnskog; Annette Säfholm; Lena Axelsson; Tommy Andersson
A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19473-8.
2009: Christian Hansen; Jill Howlin; Anders Tengholm; Oleg Dyachok; Wolfgang F Vogel; Angus Nairn; Paul Greengard; Tommy Andersson
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
The Journal of biological chemistry 2009;284(40):27533-43.
2009: Catharina Medrek; Göran Landberg; Tommy Andersson; Karin Leandersson
Wnt-5a-CKI{alpha} signaling promotes {beta}-catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells.
The Journal of biological chemistry 2009;284(16):10968-79.
2008: Annette Säfholm; Johanna Tuomela; Jeanette Rosenkvist; Janna Dejmek; Pirkko Härkönen; Tommy Andersson
The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(20):6556-63.
2006: Veronika Jenei; Ravi Kiran Deevi; Catherine Anne Adams; Lena Axelsson; David Graham Hirst; Tommy Andersson; Karim Dib
Nitric oxide produced in response to engagement of beta2 integrins on human neutrophils activates the monomeric GTPases Rap1 and Rap2 and promotes adhesion.
The Journal of biological chemistry 2006;281(46):35008-20.
2006: Janna Dejmek; Annette Säfholm; Christian Kamp Nielsen; Tommy Andersson; Karin Leandersson
Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.
Molecular and cellular biology 2006;26(16):6024-36.
2006: Annette Säfholm; Karin Leandersson; Janna Dejmek; Christian Kamp Nielsen; Bruno Villoutreix; Tommy Andersson
A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.
The Journal of biological chemistry 2006;281(5):2740-9.
2006: Karin Leandersson; Kristian Riesbeck; Tommy Andersson
Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.
Nucleic acids research 2006;34(14):3988-99.
2005: Veronika Jenei; Tommy Andersson; Judit Jakus; Karim Dib
E3B1, a human homologue of the mouse gene product Abi-1, sensitizes activation of Rap1 in response to epidermal growth factor.
Experimental cell research 2005;310(2):463-73.
2005: Janna Dejmek; Annika Dejmek; Annette Säfholm; Anita Sjölander; Tommy Andersson
Wnt-5a protein expression in primary dukes B colon cancers identifies a subgroup of patients with good prognosis.
Cancer research 2005;65(20):9142-6.
2005: Maria Nilsson; Maria Weineisen; Tommy Andersson; Lennart Truedsson; Ulf Sjöbring
Critical role for complement receptor 3 (CD11b/CD18), but not for Fc receptors, in killing of Streptococcus pyogenes by neutrophils in human immune serum.
European journal of immunology 2005;35(5):1472-81.
2005: Maria Alvarado-Kristensson; Tommy Andersson
Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3.
The Journal of biological chemistry 2005;280(7):6238-44.
2005: Janna Dejmek; Karin Leandersson; Jonas Manjer; Anders Bjartell; Stefan Emdin; Wolfgang F Vogel; Göran Landberg; Tommy Andersson
Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):520-8.
2004: Simone Grethe; Mikko P S Ares; Tommy Andersson; M Isabella Pörn-Ares
p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).
Experimental cell research 2004;298(2):632-42.
2004: Fredrik Melander; Tommy Andersson; Karim Dib
Engagement of beta2 integrins recruits 14-3-3 proteins to c-Cbl in human neutrophils.
Biochemical and biophysical research communications 2004;317(4):1000-5.
2004: Maria Weineisen; Ulf Sjöbring; Maria Fällman; Tommy Andersson
Streptococcal M5 protein prevents neutrophil phagocytosis by interfering with CD11b/CD18 receptor-mediated association and signaling.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3798-807.
2004: Maria Alvarado-Kristensson; Fredrik Melander; Karin Leandersson; Lars Rönnstrand; Christer Wernstedt; Tommy Andersson
p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils.
The Journal of experimental medicine 2004;199(4):449-58.
2003: M Isabella Pörn-Ares; Takaomi C Saido; Tommy Andersson; Mikko P S Ares
Oxidized low-density lipoprotein induces calpain-dependent cell death and ubiquitination of caspase 3 in HMEC-1 endothelial cells.
The Biochemical journal 2003;374(Pt 2):403-11.
2003: Karim Dib; Fredrik Melander; Lena Axelsson; Marie-Claire Dagher; Pontus Aspenström; Tommy Andersson
Down-regulation of Rac activity during beta 2 integrin-mediated adhesion of human neutrophils.
The Journal of biological chemistry 2003;278(26):24181-8.
2003: R Chihab; M Isabella Pörn-Ares; Maria Alvarado-Kristensson; Tommy Andersson
Sphingosine 1-phosphate antagonizes human neutrophil apoptosis via p38 mitogen-activated protein kinase.
Cellular and molecular life sciences : CMLS 2003;60(4):776-85.
2003: Fredrik Melander; Tommy Andersson; Karim Dib
Fgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils.
The Biochemical journal 2003;370(Pt 2):687-94.
2003: Janna Dejmek; Karim Dib; Marzieh Jönsson; Tommy Andersson
Wnt-5a and G-protein signaling are required for collagen-induced DDR1 receptor activation and normal mammary cell adhesion.
International journal of cancer. Journal international du cancer 2003;103(3):344-51.
2002: Ivan Dimitrijevic; Lena Axelsson; Tommy Andersson
The adhesion receptor CD-31 can be primed to rapidly adjust the neutrophil cytoskeleton.
Biochemical and biophysical research communications 2002;292(4):1092-7.
2002: Marzieh Jönsson; Janna Dejmek; Pär-Ola Bendahl; Tommy Andersson
Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas.
Cancer research 2002;62(2):409-16.
2002: Maria Alvarado-Kristensson; M Isabella Porn-Ares; Simone Grethe; David Smith; Limin Zheng; Tommy Andersson
p38 Mitogen-activated protein kinase and phosphatidylinositol 3-kinase activities have opposite effects on human neutrophil apoptosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(1):129-31.
2001: Karim Dib; Fredrik Melander; Tommy Andersson
Role of p190RhoGAP in beta 2 integrin regulation of RhoA in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6311-22.
2000: Lena Axelsson; C Hellberg; Fredrik Melander; D Smith; L Zheng; Tommy Andersson
Clustering of beta(2)-integrins on human neutrophils activates dual signaling pathways to PtdIns 3-kinase.
Experimental cell research 2000;256(1):257-63.
1999: C Hellberg; L Ydrenius; Lena Axelsson; Tommy Andersson
Disruption of beta(2)-integrin-cytoskeleton coupling abolishes the signaling capacity of these integrins on granulocytes.
Biochemical and biophysical research communications 1999;265(1):164-9.
1997: L Zheng; J Eckerdal; I Dimitrijevic; Tommy Andersson
Chemotactic peptide-induced activation of Ras in human neutrophils is associated with inhibition of p120-GAP activity.
The Journal of biological chemistry 1997;272(37):23448-54.
1997: L Ydrenius; L Molony; J Ng-Sikorski; Tommy Andersson
Dual action of cAMP-dependent protein kinase on granulocyte movement.
Biochemical and biophysical research communications 1997;235(3):445-50.
1996: J Ng-Sikorski; L Lindén; D Eierman; L Franzen; L Molony; Tommy Andersson
Engagement of L-selectin impairs the actin polymerizing capacity of beta 2-integrins on neutrophils.
Journal of cell science 1996;109 ( Pt 9)():2361-9.
1996: L Zheng; Anita Sjölander; J Eckerdal; Tommy Andersson
Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8431-6.
1996: C Hellberg; L Molony; L Zheng; Tommy Andersson
Ca2+ signalling mechanisms of the beta 2 integrin on neutrophils: involvement of phospholipase C gamma 2 and Ins(1,4,5)P3.
The Biochemical journal 1996;317 ( Pt 2)():403-9.
1996: L Molony; J Ng-Sikorski; C Hellberg; Tommy Andersson
Inhibitors of farnesyl and geranylgeranyl methyltransferases prevent beta 2 integrin-induced actin polymerization without affecting beta 2 integrin-induced Ca2+ signaling in neutrophils.
Biochemical and biophysical research communications 1996;223(3):612-7.
1996: E Särndahl; G M Bokoch; F Boulay; Olle Stendahl; Tommy Andersson
Direct or C5a-induced activation of heterotrimeric Gi2 proteins in human neutrophils is associated with interaction between formyl peptide receptors and the cytoskeleton.
The Journal of biological chemistry 1996;271(25):15267-71.
1996: E Grönroos; Tommy Andersson; A Schippert; L Zheng; Anita Sjölander
Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho.
The Biochemical journal 1996;316 ( Pt 1)():239-45.
1995: A Johansson; E Särndahl; Tommy Andersson; Torbjörn Bengtsson; H Lundqvist; Claes Dahlgren
Chemoattractant-induced NADPH oxidase activity in human monocytes is terminated without any association of receptor-ligand complex to cytoskeleton.
Inflammation 1995;19(2):179-91.
1995: C Hellberg; D Eierman; Anita Sjölander; Tommy Andersson
The Ca2+ signaling capacity of the beta 2-integrin on HL60-granulocytic cells is abrogated following phosphorylation of its CD18-chain: relation to impaired protein tyrosine phosphorylation.
Experimental cell research 1995;217(1):140-8.
1994: D Eierman; C Hellberg; Anita Sjölander; Tommy Andersson
Chemotactic factor receptor activation transiently impairs the Ca2+ signaling capacity of beta 2 integrins on human neutrophils.
Experimental cell research 1994;215(1):90-6.
1993: R Löfgren; J Ng-Sikorski; Anita Sjölander; Tommy Andersson
Beta 2 integrin engagement triggers actin polymerization and phosphatidylinositol trisphosphate formation in non-adherent human neutrophils.
The Journal of cell biology 1993;123(6 Pt 1):1597-605.
1993: E Särndahl; G M Bokoch; Olle Stendahl; Tommy Andersson
Stimulus-induced dissociation of alpha subunits of heterotrimeric GTP-binding proteins from the cytoskeleton of human neutrophils.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6552-6.
1993: Maria Fällman; R Andersson; Tommy Andersson
Signaling properties of CR3 (CD11b/CD18) and CR1 (CD35) in relation to phagocytosis of complement-opsonized particles.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):330-8.
1992: Maria Fällman; M Gullberg; C Hellberg; Tommy Andersson
Complement receptor-mediated phagocytosis is associated with accumulation of phosphatidylcholine-derived diglyceride in human neutrophils. Involvement of phospholipase D and direct evidence for a positive feedback signal of protein kinase.
The Journal of biological chemistry 1992;267(4):2656-63.
1991: E Särndahl; G M Bokoch; K Spicher; Olle Stendahl; Tommy Andersson
G-proteins and the association of ligand/receptor complexes with the cytoskeleton in human neutrophils.
Biochemical Society transactions 1991;19(4):1127-9.
1991: J Ng-Sikorski; R Andersson; M Patarroyo; Tommy Andersson
Calcium signaling capacity of the CD11b/CD18 integrin on human neutrophils.
Experimental cell research 1991;195(2):504-8.
1991: Torbjörn Bengtsson; Claes Dahlgren; Olle Stendahl; Tommy Andersson
Actin assembly and regulation of neutrophil function: effects of cytochalasin B and tetracaine on chemotactic peptide-induced O2- production and degranulation.
Journal of leukocyte biology 1991;49(3):236-44.
1990: Anita Sjölander; E Grönroos; Sven Hammarström; Tommy Andersson
Leukotriene D4 and E4 induce transmembrane signaling in human epithelial cells. Single cell analysis reveals diverse pathways at the G-protein level for the influx and the intracellular mobilization of Ca2+.
The Journal of biological chemistry 1990;265(34):20976-81.
1990: Maria Fällman; H Bergstrand; Tommy Andersson
Auranofin dissociates chemotactic peptide-induced generation of inositol 1,4,5-trisphosphate from the subsequent mobilization of intracellular calcium in intact human neutrophils.
Biochimica et biophysica acta 1990;1055(2):173-8.
1990: Torbjörn Bengtsson; E Särndahl; Olle Stendahl; Tommy Andersson
Involvement of GTP-binding proteins in actin polymerization in human neutrophils.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):2921-5.
1990: Matthias P Wymann; P Kernen; Torbjörn Bengtsson; Tommy Andersson; Marco Baggiolini; D A Deranleau
Corresponding oscillations in neutrophil shape and filamentous actin content.
The Journal of biological chemistry 1990;265(2):619-22.
1989: E Särndahl; M Lindroth; Torbjörn Bengtsson; Maria Fällman; J Gustavsson; Olle Stendahl; Tommy Andersson
Association of ligand-receptor complexes with actin filaments in human neutrophils: a possible regulatory role for a G-protein.
The Journal of cell biology 1989;109(6 Pt 1):2791-9.
1989: Maria Fällman; Daniel Lew; Olle Stendahl; Tommy Andersson
Receptor-mediated phagocytosis in human neutrophils is associated with increased formation of inositol phosphates and diacylglycerol. Elevation in cytosolic free calcium and formation of inositol phosphates can be dissociated from accumulation of diacylglycerol.
The Journal of clinical investigation 1989;84(3):886-91.
1989: Maria Fällman; Olle Stendahl; Tommy Andersson
Phorbol ester-induced activation of protein kinase C leads to increased formation of diacylglycerol in human neutrophils.
Experimental cell research 1989;181(1):217-25.
1988: Torbjörn Bengtsson; Ingemar Rundquist; Olle Stendahl; Matthias P Wymann; Tommy Andersson
Increased breakdown of phosphatidylinositol 4,5-bisphosphate is not an initiating factor for actin assembly in human neutrophils.
The Journal of biological chemistry 1988;263(33):17385-9.
1988: Tommy Andersson; Maria Fällman; Daniel Lew; Olle Stendahl
Does protein kinase C control receptor-mediated phagocytosis in human neutrophils?
FEBS letters 1988;239(2):371-5.