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David Erlinge

Research Profile

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Martin Annborn; Josef Dankiewicz; David Erlinge; Sabine Hertel; Malin Rundgren; J Gustav Smith; Joachim Struck; Hans Friberg
Procalcitonin after cardiac arrest - An indicator of severity of illness, ischemia-reperfusion injury and outcome.
Olof Gidlöf; Patrik Gilje; Jenny Ohman; Björn Olde; Marcel van der Brug; Claes Wahlestedt; David Erlinge
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression.
Marina M Demidova; David Erlinge; Sasha Koul; Pablo Laguna; Juan Pablo Martínez; Alba Martín-Yebra; Violeta Monasterio; Daniel Romero; Jesper van der Pals; Pyotr G Platonov
T wave alternans in experimental myocardial infarction: Time course and predictive value for the assessment of myocardial damage.

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2013: Martin Annborn; Josef Dankiewicz; David Erlinge; Sabine Hertel; Malin Rundgren; J Gustav Smith; Joachim Struck; Hans Friberg
Procalcitonin after cardiac arrest - An indicator of severity of illness, ischemia-reperfusion injury and outcome.
Resuscitation 2013;84(6):782-7.
2013: Olof Gidlöf; Patrik Gilje; Jenny Ohman; Björn Olde; Marcel van der Brug; Claes Wahlestedt; David Erlinge
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression.
Blood 2013;121(19):3908-17.
2013: Marina M Demidova; David Erlinge; Sasha Koul; Pablo Laguna; Juan Pablo Martínez; Alba Martín-Yebra; Violeta Monasterio; Daniel Romero; Jesper van der Pals; Pyotr G Platonov
T wave alternans in experimental myocardial infarction: Time course and predictive value for the assessment of myocardial damage.
Journal of electrocardiology 2013;46(3):263-9.
2013: Chanyuan Tan; Ulrikke Voss; David Erlinge; Siv Svensson; Björn Olde
High glucose and free fatty acids induce beta cell apoptosis via autocrine effects of ADP acting on the P2Y(13) receptor.
Purinergic signalling 2013;9(1):67-79.
2013: Joey F A Ubachs; Jesper van der Pals; Patrik Andersson; Marcus Carlsson; Henrik Engblom; David Erlinge; Mikael Kanski; Sasha Koul; Håkan Arheden
Myocardium at risk can be determined by ex vivo T2-weighted magnetic resonance imaging even in the presence of gadolinium: comparison to myocardial perfusion single photon emission computed tomography.
European heart journal cardiovascular Imaging 2013;14(3):261-8.
2013: Ramasri Sathanoori; David Erlinge; Olga Göransson; Björn Olde; Nils Wierup
Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation.
The Journal of biological chemistry 2013;288(5):3208-18.
2013: Jeanette Westman; Kristian Wahlbeck; Lars Alfredsson; David Erlinge; Jonas Hällgren; Urban Osby
Cardiovascular mortality in bipolar disorder: a population-based cohort study in Sweden.
BMJ open 2013;3(4):.
2013: Kristina Torngren; Johan Larsson; Jenny Ohman; Hanna Salmi; David Erlinge
Ticagrelor improves peripheral arterial function in patients with a previous acute coronary syndrome.
Cardiology 2013;124(4):252-8.
2013: Olof Gidlöf; Patrik Gilje; Kazuma Miyazu; J Gustav Smith; Anna Spencer; Sten Blomquist; David Erlinge
Circulating cardio-enriched microRNAs are associated with long-term prognosis following myocardial infarction.
BMC cardiovascular disorders 2013;13():12.
2012: David Erlinge; David Foley; Joseph A Jakubowski; Stefan James; Junxiang Luo; Brian Moser; David S Small; Jurrien Ten Berg; Henrik Wagner; Dominick J Angiolillo; Thomas Bergmeijer; Patricia B Brown; Chunmei Zhou; Kenneth J Winters
Reduction in platelet reactivity with prasugrel 5 mg in low-body-weight patients is noninferior to prasugrel 10 mg in higher-body-weight patients: results from the FEATHER trial.
Journal of the American College of Cardiology 2012;60(20):2032-40.
2012: Paul A Gurbel; Kurt Huber; Joseph A Jakubowski; Benjamin Neely; Megan Neely; E Magnus Ohman; Dorairaj Prabhakaran; Matthew T Roe; Udaya S Tantry; Harvey D White; Chunmei Zhou; Paul W Armstrong; Eileen Brown; Mark Y Chan; Jan H Cornel; David Erlinge; Keith A A Fox; Shaun G Goodman
Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: the TRILOGY ACS platelet function substudy.
JAMA : the journal of the American Medical Association 2012;308(17):1785-94.
2012: Jenny Öhman; David Erlinge
The touching story of purinergic signaling in epithelial and endothelial cells.
Purinergic signalling 2012;8(3):599-608.
2012: Joseph A Jakubowski; Amy G Leishman; Jeffrey S Riesmeyer; Sandra L Close; David Erlinge
TRITON and beyond: new insights into the profile of prasugrel.
Cardiovascular therapeutics 2012;30(4):e174-82.
2012: Jenny Ohman; Björn Olde; Sebastian Albinsson; Ramesh Kudira; David Erlinge
Ticagrelor induces adenosine triphosphate release from human red blood cells.
Biochemical and biophysical research communications 2012;418(4):754-8.
2012: Patrik Andersson; Oscar O Braun; Olof Gidlöf; Matthias Götberg; Björn Olde; Jesper van der Pals; David Erlinge
Plasma levels of liver-specific miR-122 is massively increased in a porcine cardiogenic shock model and attenuated by hypothermia.
Shock (Augusta, Ga.) 2012;37(2):234-8.
2012: Olof Gidlöf; Bo Hedblad; Christina Jern; Katarina Jood; Arne Lindgren; Håkan Lövkvist; Olle Melander; Peter Nilsson; Bo Norrving; Sandra Olsson; J Gustav Smith; Göran Berglund; Joyce Carlson; Gunnar Engström; David Erlinge
A common missense variant in the ATP receptor P2X7 is associated with reduced risk of cardiovascular events.
PloS one 2012;7(5):e37491.
2011: Sasha Koul; Bo Lagerqvist; Fredrik Scherstén; J Gustav Smith; Stefan James; David Erlinge
Effect of upstream clopidogrel treatment in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
European heart journal 2011;32(23):2989-97.
2011: Matthias Götberg; Michael Götberg; Mikael Kanski; Sasha Koul; Goran Olivecrona; Andreas Otto; Martin Ugander; Jesper van der Pals; Håkan Arheden; Henrik Engblom; David Erlinge
Optimal timing of hypothermia in relation to myocardial reperfusion.
Basic research in cardiology 2011;106(5):697-708.
2011: Henrik Engblom; David Erlinge; Matthias Götberg; Bo Heden; Erik Hedström; Stefan Jovinge; David Strauss; Galen S Wagner; Håkan Arheden
The evaluation of an electrocardiographic myocardial ischemia acuteness score to predict the amount of myocardial salvage achieved by early percutaneous coronary intervention Clinical validation with myocardial perfusion single photon emission computed tomography and cardiac magnetic resonance.
Journal of electrocardiology 2011;44(5):525-32.
2011: Christoph Varenhorst; Lars Wallentin; David Erlinge; Sasha Koul; Bo Lagerqvist; Agneta Siegbahn; Stefan James
Relationship between clopidogrel-induced platelet P2Y12 inhibition and stent thrombosis or myocardial infarction after percutaneous coronary intervention-a case-control study.
American heart journal 2011;162(2):363-71.
2011: Jesper van der Pals; Matthias Götberg; Michael I Götberg; Lillemor Mattsson Hultén; Sverker Jern; Mia Magnusson; David Erlinge
Hypothermia in cardiogenic shock reduces systemic t-PA release.
Journal of thrombosis and thrombolysis 2011;32(1):72-81.
2011: Magnus Settergren; David Erlinge; Anders Jönsson; Niels Erik Nielsen; Eva Nylander; Jan Harnek
[Mitral valve disease:"Now we can both open and close"].
Läkartidningen 2011;108(20):1117-22.
2011: C Högberg; O Gidlöf; C Tan; S Svensson; J Nilsson-Öhman; David Erlinge; B Olde
Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling.
Journal of thrombosis and haemostasis : JTH 2011;9(2):361-72.
2011: Olof Gidlöf; Matthias Götberg; Jesper van der Pals; Patrik Andersson; David Erlinge
Cardiospecific microRNA plasma levels correlate with troponin and cardiac function in patients with ST elevation myocardial infarction, are selectively dependent on renal elimination, and can be detected in urine samples.
Cardiology 2011;118(4):217-26.
2011: David Erlinge
P2Y receptors in health and disease.
Advances in pharmacology (San Diego, Calif.) 2011;61():417-39.
2011: Marina M Demidova; Jesper van der Pals; Joey F A Ubachs; Mikael Kanski; Henrik Engblom; David Erlinge; Victor M Tichonenko; Pyotr G Platonov
ST-segment dynamics during reperfusion period and the size of myocardial injury in experimental myocardial infarction.
Journal of electrocardiology 2011;44(1):74-81.
2010: Stefan James; Dominick J Angiolillo; Jan H Cornel; David Erlinge; Steen E Husted; Fredrik Kontny; Juan Maya; Josë C Nicolau; Jindrich Spinar; Robert F Storey; Susanna R Stevens; Lars Wallentin
Ticagrelor vs. clopidogrel in patients with acute coronary syndromes and diabetes: a substudy from the PLATelet inhibition and patient Outcomes (PLATO) trial.
European heart journal 2010;31(24):3006-16.
2010: Matthias Götberg; Goran Olivecrona; Sasha Koul; Marcus Carlsson; Henrik Engblom; Martin Ugander; Jesper van der Pals; Lars Algotsson; Håkan Arheden; David Erlinge
A pilot study of rapid cooling by cold saline and endovascular cooling before reperfusion in patients with ST-elevation myocardial infarction.
Circulation. Cardiovascular interventions 2010;3(5):400-7.
2010: Dan Gothefors; Rolf Adolfsson; Stig Attvall; David Erlinge; Håkan Jarbin; Kjell Lindström; Yvonne Linné von Hausswolff-Juhlin; Roland Morgell; Eva Toft; Urban Osby
Swedish clinical guidelines--prevention and management of metabolic risk in patients with severe psychiatric disorders.
Nordic journal of psychiatry 2010;64(5):294-302.
2010: Christian Lood; Stefan Amisten; Birgitta Gullstrand; Andreas Jönsen; Maria Allhorn; Lennart Truedsson; Gunnar Sturfelt; David Erlinge; Anders A Bengtsson
Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease.
Blood 2010;116(11):1951-7.
2010: Matthias Götberg; Jesper van der Pals; Goran Olivecrona; Michael Götberg; Sasha Koul; David Erlinge
Mild hypothermia reduces acute mortality and improves hemodynamic outcome in a cardiogenic shock pig model.
Resuscitation 2010;81(9):1190-6.
2010: Martin Ugander; Mikael Kanski; Henrik Engblom; Matthias Götberg; Goran Olivecrona; David Erlinge; Einar Heiberg; Håkan Arheden
Pulmonary blood volume variation decreases after myocardial infarction in pigs: a quantitative and noninvasive MR imaging measure of heart failure.
Radiology 2010;256(2):415-23.
2010: Carl Högberg; Helen Svensson; Ronny Gustafsson; Atli Eyjolfsson; David Erlinge
The reversible oral P2Y12 antagonist AZD6140 inhibits ADP-induced contractions in murine and human vasculature.
International journal of cardiology 2010;142(2):187-92.
2010: Conor McCloskey; Sarah Jones; Stefan Amisten; Roger T Snowden; Leonard K Kaczmarek; David Erlinge; Alison H Goodall; Ian D Forsythe; Martyn P Mahaut-Smith
Kv1.3 is the exclusive voltage-gated K+ channel of platelets and megakaryocytes: roles in membrane potential, Ca2+ signalling and platelet count.
The Journal of physiology 2010;588(Pt 9):1399-406.
2010: Maya Landenhed; Malin Johansson; David Erlinge; Martin L Olsson; Henrik Bjursten
Fondaparinux or enoxaparin: a comparative study of postoperative bleeding in coronary artery bypass grafting surgery.
Scandinavian cardiovascular journal : SCJ 2010;44(2):100-6.
2010: Jesper van der Pals; Matthias Götberg; Goran Olivecrona; Helen Brogren; Sverker Jern; David Erlinge
Mild hypothermia markedly reduces ischemia related coronary t-PA release.
Journal of thrombosis and thrombolysis 2010;29(3):289-95.
2010: Chanyuan Tan; Albert Salehi; Siv Svensson; Björn Olde; David Erlinge
ADP receptor P2Y(13) induce apoptosis in pancreatic beta-cells.
Cellular and molecular life sciences : CMLS 2010;67(3):445-53.
2010: Jesper van der Pals; Sasha Koul; Patrik Andersson; Matthias Götberg; Joey F A Ubachs; Mikael Kanski; Håkan Arheden; Goran Olivecrona; Bengt Larsson; David Erlinge
Treatment with the C5a receptor antagonist ADC-1004 reduces myocardial infarction in a porcine ischemia-reperfusion model.
BMC cardiovascular disorders 2010;10():45.
2010: David Erlinge
Can we do more for the STEMI patient than restore coronary blood flow?
Cardiology 2010;116(2):101-2.
2010: Joey F A Ubachs; Henrik Engblom; David Erlinge; Stefan Jovinge; Erik Hedström; Marcus Carlsson; Håkan Arheden
Cardiovascular magnetic resonance of the myocardium at risk in acute reperfused myocardial infarction: comparison of T2-weighted imaging versus the circumferential endocardial extent of late gadolinium enhancement with transmural projection.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2010;12():18.
2010: Sigurdur S Stephensen; Marcus Carlsson; Martin Ugander; Henrik Engblom; Goran Olivecrona; David Erlinge; Håkan Arheden
Agreement of left ventricular mass in steady state free precession and delayed enhancement MR images: implications for quantification of fibrosis in congenital and ischemic heart disease.
BMC medical imaging 2010;10():4.
2010: Jesper van der Pals; Sasha Koul; Michael I Götberg; Goran Olivecrona; Martin Ugander; Mikael Kanski; Andreas Otto; Matthias Götberg; Håkan Arheden; David Erlinge
Apyrase treatment of myocardial infarction according to a clinically applicable protocol fails to reduce myocardial injury in a porcine model.
BMC cardiovascular disorders 2010;10():1.
2009: Christoph Varenhorst; Stefan James; David Erlinge; John T Brandt; Oscar O Braun; Michael Man; Agneta Siegbahn; Joseph Walker; Lars Wallentin; Kenneth J Winters; Sandra L Close
Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease.
European heart journal 2009;30(14):1744-52.
2009: Christoph Varenhorst; Stefan James; David Erlinge; Oscar O Braun; John T Brandt; Kenneth J Winters; Joseph A Jakubowski; Sylvia Olofsson; Lars Wallentin; Agneta Siegbahn
Assessment of P2Y(12) inhibition with the point-of-care device VerifyNow P2Y12 in patients treated with prasugrel or clopidogrel coadministered with aspirin.
American heart journal 2009;157(3):562.e1-9.
2009: Carl Högberg; David Erlinge; Oscar O Braun
Mild hypothermia does not attenuate platelet aggregation and may even increase ADP-stimulated platelet aggregation after clopidogrel treatment.
Thrombosis journal 2009;7():2.
2008: David Erlinge; Christoph Varenhorst; Oscar O Braun; Stefan James; Kenneth J Winters; Joseph A Jakubowski; John T Brandt; Atsuhiro Sugidachi; Agneta Siegbahn; Lars Wallentin
Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo.
Journal of the American College of Cardiology 2008;52(24):1968-77.
2008: Oscar O Braun; Matilda Johnell; Christoph Varenhorst; Stefan James; John T Brandt; Joseph A Jakubowski; Kenneth J Winters; Lars Wallentin; David Erlinge; Agneta Siegbahn
Greater reduction of platelet activation markers and platelet-monocyte aggregates by prasugrel compared to clopidogrel in stable coronary artery disease.
Thrombosis and haemostasis 2008;100(4):626-33.
2008: Oscar O Braun; Jan E Slotta; Michael D Menger; David Erlinge; Henrik Thorlacius
Primary and secondary capture of platelets onto inflamed femoral artery endothelium is dependent on P-selectin and PSGL-1.
European journal of pharmacology 2008;592(1-3):128-32.
2008: Fariborz Parandeh; Sandra Meidute Abaraviciene; Stefan Amisten; David Erlinge; Albert Salehi
Uridine diphosphate (UDP) stimulates insulin secretion by activation of P2Y6 receptors.
Biochemical and biophysical research communications 2008;370(3):499-503.
2008: Gwen Tolhurst; Richard N Carter; Stefan Amisten; Jon P Holdich; David Erlinge; Martyn P Mahaut-Smith
Expression profiling and electrophysiological studies suggest a major role for Orai1 in the store-operated Ca2+ influx pathway of platelets and megakaryocytes.
Platelets 2008;19(4):308-13.
2008: David Erlinge; Geoffrey Burnstock
P2 receptors in cardiovascular regulation and disease.
Purinergic signalling 2008;4(1):1-20.
2008: Einar Heiberg; Martin Ugander; Henrik Engblom; Matthias Götberg; Goran Olivecrona; David Erlinge; Håkan Arheden
Automated quantification of myocardial infarction from MR images by accounting for partial volume effects: animal, phantom, and human study.
Radiology 2008;246(2):581-8.
2008: Matthias Götberg; Goran Olivecrona; Henrik Engblom; Martin Ugander; Jesper van der Pals; Einar Heiberg; Håkan Arheden; David Erlinge
Rapid short-duration hypothermia with cold saline and endovascular cooling before reperfusion reduces microvascular obstruction and myocardial infarct size.
BMC cardiovascular disorders 2008;8():7.
2008: Stefan Amisten; Oscar O Braun; Lovisa Johansson; Martin Ridderstråle; Olle Melander; David Erlinge
The P2Y 13 Met-158-Thr polymorphism, which is in linkage disequilibrium with the P2Y 12 locus, is not associated with acute myocardial infarction.
PloS one 2008;3(1):e1462.
2008: Lars Wallentin; Christoph Varenhorst; Stefan James; David Erlinge; Oscar O Braun; Joseph A Jakubowski; Atsuhiro Sugidachi; Kenneth J Winters; Agneta Siegbahn
Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease.
European heart journal 2008;29(1):21-30.
2008: Stefan Amisten; Oscar O Braun; Anders Bengtsson; David Erlinge
Gene expression profiling for the identification of G-protein coupled receptors in human platelets.
Thrombosis research 2008;122(1):47-57.
2007: Goran Olivecrona; Matthias Götberg; Jan Harnek; Kenneth Alan Jacobson; Sverker Jern; David Erlinge
The ADP receptor P2Y(1) mediates t-PA release in pigs during cardiac ischemia.
Journal of thrombosis and thrombolysis 2007;24(2):115-22.
2007: Oscar O Braun; Stefan Amisten; Anna-Karin Wihlborg; Karen Hunting; David Nilsson; David Erlinge
Residual platelet ADP reactivity after clopidogrel treatment is dependent on activation of both the unblocked P2Y(1) and the P2Y (12) receptor and is correlated with protein expression of P2Y (12).
Purinergic signalling 2007;3(3):195-201.
2007: Goran Olivecrona; Matthias Götberg; Jan Harnek; Jesper Van der Pals; David Erlinge
Mild hypothermia reduces cardiac post-ischemic reactive hyperemia.
BMC cardiovascular disorders 2007;7():5.
2007: Stefan Amisten; Olle Melander; Anna-Karin Wihlborg; Göran Berglund; David Erlinge
Increased risk of acute myocardial infarction and elevated levels of C-reactive protein in carriers of the Thr-87 variant of the ATP receptor P2Y11.
European heart journal 2007;28(1):13-8.
2006: Anna-Karin Wihlborg; Johanna Balogh; Lingwei Wang; Catharina Borna; Ying Dou; Bhalchandra V Joshi; Eduardo R Lazarowski; Kenneth Alan Jacobson; Anders Arner; David Erlinge
Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction.
Circulation research 2006;98(7):970-6.
2006: Jenny Nilsson; Lisa M Nilsson; Yung-Wu Chen; Jeffery D Molkentin; David Erlinge; Maria F Gomez
High glucose activates nuclear factor of activated T cells in native vascular smooth muscle.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(4):794-800.
2005: Oscar O Braun; Anita Jagroop; Lingwei Wang; Dimitri P Mikhailidis; Geoffrey Burnstock; David Erlinge
Increased platelet purinergic sensitivity in peripheral arterial disease--a pilot study.
Platelets 2005;16(5):261-7.
2005: Johanna Balogh; Anna-Karin Wihlborg; Henrik Isackson; Bhalchandra V Joshi; Kenneth Alan Jacobson; Anders Arner; David Erlinge
Phospholipase C and cAMP-dependent positive inotropic effects of ATP in mouse cardiomyocytes via P2Y11-like receptors.
Journal of molecular and cellular cardiology 2005;39(2):223-30.
2005: Catharina Borna; Eduardo R Lazarowski; Catharina van Heusden; Hans Ohlin; David Erlinge
Resistance to aspirin is increased by ST-elevation myocardial infarction and correlates with adenosine diphosphate levels.
Thrombosis journal 2005;3():10.
2005: David Erlinge; Jan Harnek; Catharina van Heusden; Goran Olivecrona; Sverker Jern; Eduardo R Lazarowski
Uridine triphosphate (UTP) is released during cardiac ischemia.
International journal of cardiology 2005;100(3):427-33.
2005: Andreas Bergdahl; Maria F Gomez; Anna-Karin Wihlborg; David Erlinge; Atli Eyjolfson; Shang-Zhong Xu; David J Beech; Karl Dreja; Per Hellstrand
Plasticity of TRPC expression in arterial smooth muscle: correlation with store-operated Ca2+ entry.
American journal of physiology. Cell physiology 2005;288(4):C872-80.
2005: Lingwei Wang; Goran Olivecrona; Matthias Götberg; Martin L Olsson; Maria Sörhede Winzell; David Erlinge
ADP acting on P2Y13 receptors is a negative feedback pathway for ATP release from human red blood cells.
Circulation research 2005;96(2):189-96.
2004: Helen Brogren; Lena Karlsson; Maria Andersson; Lingwei Wang; David Erlinge; Sverker Jern
Platelets synthesize large amounts of active plasminogen activator inhibitor 1.
Blood 2004;104(13):3943-8.
2004: Goran Olivecrona; Matthias Gotberg; Jan Harnek; Lingwei Wang; Kenneth Alan Jacobson; David Erlinge
Coronary artery reperfusion: The ADP receptor P2Y(1) mediates early reactive hyperemia in vivo in pigs.
Purinergic signalling 2004;1(1):59-65.
2004: Anna-Karin Wihlborg; Lingwei Wang; Oscar O Braun; Atli Eyjolfsson; Ronny Gustafsson; Tomas Gudbjartsson; David Erlinge
ADP receptor P2Y12 is expressed in vascular smooth muscle cells and stimulates contraction in human blood vessels.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(10):1810-5.
2004: Lingwei Wang; Sten Eirik W Jacobsen; Anders Bengtsson; David Erlinge
P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells.
BMC immunology 2004;5():16.
2004: Lingwei Wang; P Erling; Anders A Bengtsson; Lennart Truedsson; Gunnar Sturfelt; David Erlinge
Transcriptional down-regulation of the platelet ADP receptor P2Y(12) and clusterin in patients with systemic lupus erythematosus.
Journal of thrombosis and haemostasis : JTH 2004;2(8):1436-42.
2004: David Erlinge
Extracellular ATP: a central player in the regulation of vascular smooth muscle phenotype. Focus on "Dual role of PKA in phenotype modulation of vascular smooth muscle cells by extracellular ATP".
American journal of physiology. Cell physiology 2004;287(2):C260-2.
2003: Lingwei Wang; Maria Andersson; Lena Karlsson; Marie-Ange Watson; Diane J Cousens; Sverker Jern; David Erlinge
Increased mitogenic and decreased contractile P2 receptors in smooth muscle cells by shear stress in human vessels with intact endothelium.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(8):1370-6.
2003: Catharina Borna; Lingwei Wang; Tomas Gudbjartsson; Lena Karlsson; Sverker Jern; Malin Malmsjö; David Erlinge
Contractions in human coronary bypass vessels stimulated by extracellular nucleotides.
The Annals of thoracic surgery 2003;76(1):50-7.
2003: Malin Malmsjö; Mingyan Hou; William Pendergast; David Erlinge; Lars Edvinsson
Potent P2Y6 receptor mediated contractions in human cerebral arteries.
BMC pharmacology 2003;3():4.
2003: Anna-Karin Wihlborg; Malin Malmsjö; Atli Eyjolfsson; Ronny Gustafsson; Kenneth Alan Jacobson; David Erlinge
Extracellular nucleotides induce vasodilatation in human arteries via prostaglandins, nitric oxide and endothelium-derived hyperpolarising factor.
British journal of pharmacology 2003;138(8):1451-8.
2003: Lingwei Wang; O Ostberg; Anna-Karin Wihlborg; Helen Brogren; Sverker Jern; David Erlinge
Quantification of ADP and ATP receptor expression in human platelets.
Journal of thrombosis and haemostasis : JTH 2003;1(2):330-6.
2003: Malin Malmsjö; Mingyan Hou; William Pendergast; David Erlinge; Lars Edvinsson
The stable pyrimidines UDPbetaS and UTPgammaS discriminate between contractile cerebrovascular P2 receptors.
European journal of pharmacology 2003;458(3):305-11.
2002: Lingwei Wang; Lena Karlsson; Sara Moses; Anna Hultgårdh-Nilsson; Maria Andersson; Catharina Borna; Tomas Gudbjartsson; Sverker Jern; David Erlinge
P2 receptor expression profiles in human vascular smooth muscle and endothelial cells.
Journal of cardiovascular pharmacology 2002;40(6):841-53.
2002: M Malmsjø; Zen Chu; K Croft; David Erlinge; Lars Edvinsson; L J Beilin
P2Y receptor-induced EDHF vasodilatation is of primary importance for the regulation of perfusion pressure in the peripheral circulation of the rat.
Acta physiologica Scandinavica 2002;174(4):301-9.
2002: Mingyan Hou; T Kendall Harden; Cynthia M Kuhn; Bo Baldetorp; Eduardo R Lazarowski; William Pendergast; Sebastian Möller; Lars Edvinsson; David Erlinge
UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y(6) receptors.
American journal of physiology. Heart and circulatory physiology 2002;282(2):H784-92.
2002: Hak-Sung Kim; R Gnana Ravi; Victor E Marquez; Savitri Maddileti; Anna-Karin Wihlborg; David Erlinge; Malin Malmsjö; José L Boyer; T Kendall Harden; Kenneth Alan Jacobson
Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.
Journal of medicinal chemistry 2002;45(1):208-18.
2001: O Saetrum Opgaard; Mikael Adner; T H Peters; Cang-Bao Xu; L Stavenow; Sergio Gulbenkian; David Erlinge; Lars Edvinsson; H S Sharma
Endocardial expression and functional characterization of endothelin-1.
Molecular and cellular biochemistry 2001;224(1-2):151-8.
2001: Thórdís Hrafnkelsdóttir; David Erlinge; Sverker Jern
Extracellular nucleotides ATP and UTP induce a marked acute release of tissue-type plasminogen activator in vivo in man.
Thrombosis and haemostasis 2001;85(5):875-81.
2000: Mingyan Hou; Sebastian Möller; Lars Edvinsson; David Erlinge
Cytokines induce upregulation of vascular P2Y(2) receptors and increased mitogenic responses to UTP and ATP.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(9):2064-9.
2000: Malin Malmsjö; Mikael Adner; T Kendall Harden; William Pendergast; Lars Edvinsson; David Erlinge
The stable pyrimidines UDPbetaS and UTPgammaS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery.
British journal of pharmacology 2000;131(1):51-6.
2000: Malin Malmsjö; Mingyan Hou; T Kendall Harden; William Pendergast; Emil Pantev; Lars Edvinsson; David Erlinge
Characterization of contractile P2 receptors in human coronary arteries by use of the stable pyrimidines uridine 5'-O-thiodiphosphate and uridine 5'-O-3-thiotriphosphate.
The Journal of pharmacology and experimental therapeutics 2000;293(3):755-60.
2000: Malin Malmsjö; Lars Edvinsson; David Erlinge
P2X receptors counteract the vasodilatory effects of endothelium derived hyperpolarising factor.
European journal of pharmacology 2000;390(1-2):173-80.
2000: Mingyan Hou; Emil Pantev; Sebastian Möller; David Erlinge; Lars Edvinsson
Angiotensin II type 1 receptors stimulate protein synthesis in human cardiac fibroblasts via a Ca2+-sensitive PKC-dependent tyrosine kinase pathway.
Acta physiologica Scandinavica 2000;168(2):301-9.
2000: T Nilsson; Thórdís Hrafnkelsdóttir; Lars Edvinsson; Sverker Jern; David Erlinge; Ulrika Wall
Forearm blood flow responses to neuropeptide Y, noradrenaline and adenosine 5'-triphosphate in hypertensive and normotensive subjects.
Blood pressure 2000;9(2-3):126-31.
1999: Malin Malmsjö; Andreas Bergdahl; Sebastian Möller; XH Zhao; XY Sun; Thomas Hedner; Lars Edvinsson; David Erlinge
Congestive heart failure induces downregulation of P2X1-receptors in resistance arteries.
Cardiovascular research 1999;43(1):219-27.
1999: Malin Malmsjö; Andreas Bergdahl; XH Zhao; XY Sun; Thomas Hedner; Lars Edvinsson; David Erlinge
Enhanced acetylcholine and P2Y-receptor stimulated vascular EDHF-dilatation in congestive heart failure.
Cardiovascular research 1999;43(1):200-9.
1999: Mingyan Hou; Sebastian Möller; Lars Edvinsson; David Erlinge
MAPKK-dependent growth factor-induced upregulation of P2Y2 receptors in vascular smooth muscle cells.
Biochemical and biophysical research communications 1999;258(3):648-52.
1999: Malin Malmsjö; David Erlinge; Edward D Högestätt; Peter M Zygmunt
Endothelial P2Y receptors induce hyperpolarisation of vascular smooth muscle by release of endothelium-derived hyperpolarising factor.
European journal of pharmacology 1999;364(2-3):169-73.
1999: Mingyan Hou; Malin Malmsjö; Sebastian Möller; Emil Pantev; Andreas Bergdahl; XH Zhao; XY Sun; Thomas Hedner; Lars Edvinsson; David Erlinge
Increase in cardiac P2X1-and P2Y2-receptor mRNA levels in congestive heart failure.
Life sciences 1999;65(11):1195-206.
1999: H Lind; Mikael Adner; David Erlinge; J Brunkwall; Lars Edvinsson
Selective increase of the contractile response to endothelin-1 in subcutaneous arteries from patients with essential hypertension.
Blood pressure 1999;8(1):9-15.
1998: A Holmgren; Emil Pantev; David Erlinge; Lars Edvinsson
Inhibition of angiotensin II-induced contraction by losartan in human coronary arteries.
Journal of cardiovascular pharmacology 1998;32(4):662-4.
1998: David Erlinge; Mingyan Hou; TE Webb; Eric A Barnard; Sebastian Möller
Phenotype changes of the vascular smooth muscle cell regulate P2 receptor expression as measured by quantitative RT-PCR.
Biochemical and biophysical research communications 1998;248(3):864-70.
1998: David Erlinge
Extracellular ATP: a growth factor for vascular smooth muscle cells.
General pharmacology 1998;31(1):1-8.
1998: Malin Malmsjö; Lars Edvinsson; David Erlinge
P2U-receptor mediated endothelium-dependent but nitric oxide-independent vascular relaxation.
British journal of pharmacology 1998;123(4):719-29.
1996: T Nilsson; David Erlinge; L Cantera; Lars Edvinsson
Contractile effects of neuropeptide Y in human subcutaneous resistance arteries are mediated by Y1 receptors.
Journal of cardiovascular pharmacology 1996;28(6):764-8.
1996: Andreas Bergdahl; T Nilsson; L Cantera; L Nilsson; XY Sun; Thomas Hedner; David Erlinge; S Valdemarson; Lars Edvinsson
Neuropeptide Y potentiates noradrenaline-induced contraction through the neuropeptide Y Y1 receptor.
European journal of pharmacology 1996;316(1):59-64.
1996: David Erlinge; Markus Heilig; Lars Edvinsson
Tyrphostin inhibition of ATP-stimulated DNA synthesis, cell proliferation and fos-protein expression in vascular smooth muscle cells.
British journal of pharmacology 1996;118(4):1028-34.
1996: XY Sun; X H Zhao; David Erlinge; Lars Edvinsson; B Fallgren; Claes Wahlestedt; Thomas Hedner
Effects of phosphorothioated neuropeptide Y Y1-receptor antisense oligodeoxynucleotide in conscious rats and in human vessels.
British journal of pharmacology 1996;118(1):131-6.
1996: X Sun; J You; Thomas Hedner; David Erlinge; B Fellström; H Yoo; Claes Wahlestedt; Lars Edvinsson
alpha-Trinositol: a functional (non-receptor) neuropeptide Y antagonist in vasculature.
The Journal of pharmacy and pharmacology 1996;48(1):77-84.
1995: T Thulin; David Erlinge
Neuropeptide Y and hypertension.
Nutrition (Burbank, Los Angeles County, Calif.) 1995;11(5 Suppl):495-7.
1995: H Lind; David Erlinge; J Brunkwall; Lars Edvinsson
Selective attenuation of neuropeptide-Y-mediated contractile responses in blood vessels from patients with diabetes mellitus.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society 1995;5(4):191-7.
1995: David Erlinge; J You; Claes Wahlestedt; Lars Edvinsson
Characterisation of an ATP receptor mediating mitogenesis in vascular smooth muscle cells.
European journal of pharmacology 1995;289(1):135-49.
1995: Mikael Adner; David Erlinge; L Nilsson; Lars Edvinsson
Upregulation of a non-ETA receptor in human arteries in vitro.
Journal of cardiovascular pharmacology 1995;26 Suppl 3():S314-6.
1994: Mikael Adner; David Erlinge; Leif G Salford; Frances Yee; Claes Wahlestedt; Lars Edvinsson
Human endothelin ETA receptor antisense oligodeoxynucleotides inhibit endothelin-1 evoked vasoconstriction.
European journal of pharmacology 1994;261(3):281-4.
1994: Lars Edvinsson; David Erlinge; XY Sun; Thomas Hedner
Neuropeptide Y in sympathetic co-transmission: recent advances in the search for neuropeptide Y antagonists.
Pharmacology & toxicology 1994;74(4-5):193-201.
1994: David Erlinge; J Brunkwall; Lars Edvinsson
Neuropeptide Y stimulates proliferation of human vascular smooth muscle cells: cooperation with noradrenaline and ATP.
Regulatory peptides 1994;50(3):259-65.
1993: C B Xu; L Stavenow; W Liao; David Erlinge; Lars Edvinsson
Interactions between cultured bovine arterial endothelial and smooth muscle cells: studies on uptake and degradation of low density lipoproteins by smooth muscle cells.
Pharmacology & toxicology 1993;73(5):269-73.
1993: David Erlinge; H Yoo; Lars Edvinsson; Donald J Reis; Claes Wahlestedt
Mitogenic effects of ATP on vascular smooth muscle cells vs. other growth factors and sympathetic cotransmitters.
The American journal of physiology 1993;265(4 Pt 2):H1089-97.
1993: David Erlinge; Lars Edvinsson; J Brunkwall; Frances Yee; Claes Wahlestedt
Human neuropeptide Y Y1 receptor antisense oligodeoxynucleotide specifically inhibits neuropeptide Y-evoked vasoconstriction.
European journal of pharmacology 1993;240(1):77-80.
1992: Lars Edvinsson; David Erlinge; Rolf Ekman; T Thulin
Sensory nerve terminal activity in severe hypertension as reflected by circulating calcitonin gene-related peptide (CGRP) and substance P.
Blood pressure 1992;1(4):223-9.
1992: David Erlinge; R Ekman; T Thulin; Lars Edvinsson
Neuropeptide Y-like immunoreactivity and hypertension.
Journal of hypertension 1992;10(10):1221-5.