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Sylvia Escher

Research Profile

Chemicals & Drugs

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Shipra Gupta; Sebastian Rieder; Rudolf Richter; Sandra Schulz-Maronde; Johanna Manns; Sylvia Escher; Aleksandra Heitland; Matthias Mack; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
CCR1- and CCR5-mediated inactivation of leukocytes by a nonglycosaminoglycan (non-GAG)-binding variant of n-nonanoyl-CCL14 (NNY-CCL14).
S Gupta; G Erdmann; Sandra Schulz-Maronde; Sylvia Escher; Rudolf Richter; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
n-Nonanoyl-CCL14 (NNY-CCL14), a novel inhibitor of allergic airway inflammation is a partial agonist of human CCR2.
Shipra Gupta; Barbara Fuchs; Sandra Schulz-Maronde; Aleksandra Heitland; Sylvia Escher; Matthias Mack; Hanns-Christian Tillmann; Armin Braun; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
Intravascular inactivation of CCR5 by n-Nonanoyl-CC chemokine ligand 14 and inhibition of allergic airway inflammation.

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All Publications

2010: Shipra Gupta; Sebastian Rieder; Rudolf Richter; Sandra Schulz-Maronde; Johanna Manns; Sylvia Escher; Aleksandra Heitland; Matthias Mack; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
CCR1- and CCR5-mediated inactivation of leukocytes by a nonglycosaminoglycan (non-GAG)-binding variant of n-nonanoyl-CCL14 (NNY-CCL14).
Journal of leukocyte biology 2010;88(2):383-92.
2008: S Gupta; G Erdmann; Sandra Schulz-Maronde; Sylvia Escher; Rudolf Richter; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
n-Nonanoyl-CCL14 (NNY-CCL14), a novel inhibitor of allergic airway inflammation is a partial agonist of human CCR2.
Allergy 2008;63(10):1317-23.
2008: Shipra Gupta; Barbara Fuchs; Sandra Schulz-Maronde; Aleksandra Heitland; Sylvia Escher; Matthias Mack; Hanns-Christian Tillmann; Armin Braun; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
Intravascular inactivation of CCR5 by n-Nonanoyl-CC chemokine ligand 14 and inhibition of allergic airway inflammation.
Journal of leukocyte biology 2008;83(3):765-73.
2007: J Manns; S Rieder; Sylvia Escher; B Eilers; Wolf-Georg Forssmann; Jörn Elsner; Ulf Forssmann
The allergy-associated chemokine receptors CCR3 and CCR5 can be inactivated by the modified chemokine NNY-CCL11.
Allergy 2007;62(1):17-24.
2006: Rudolf Richter; Ulf Forssmann; Reinhard Henschler; Sylvia Escher; Adjoa Frimpong-Boateng; Wolf-Georg Forssmann
Increase of expression and activation of chemokine CCL15 in chronic renal failure.
Biochemical and biophysical research communications 2006;345(4):1504-12.
2005: Jörn Elsner; Yasmin Dulkys; S Gupta; Sylvia Escher; Wolf-Georg Forssmann; Alexander Kapp; Ulf Forssmann
Differential pattern of CCR1 internalization in human eosinophils: prolonged internalization by CCL5 in contrast to CCL3.
Allergy 2005;60(11):1386-93.
2005: Rudolf Richter; Roxana Bistrian; Sylvia Escher; Wolf-Georg Forssmann; Jalal Vakili; Reinhard Henschler; Nikolaj Spodsberg; Adjoa Frimpong-Boateng; Ulf Forssmann
Quantum proteolytic activation of chemokine CCL15 by neutrophil granulocytes modulates mononuclear cell adhesiveness.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1599-608.
2004: Jörn Elsner; Sylvia Escher; Ulf Forssmann
Chemokine receptor antagonists: a novel therapeutic approach in allergic diseases.
Allergy 2004;59(12):1243-58.
2004: Yasmin Dulkys; T Buschermöhle; Sylvia Escher; Alexander Kapp; Jörn Elsner
T-helper 2 cytokines attenuate senescent eosinophil activation by the CXCR4 ligand stromal-derived factor-1alpha (CXCL12).
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(10):1610-20.
2004: Ulf Forssmann; Inka Hartung; Ralf Bälder; Barbara Fuchs; Sylvia Escher; Nikolaj Spodsberg; Yasmin Dulkys; Michael Walden; Aleksandra Heitland; Armin Braun; Wolf-Georg Forssmann; Jörn Elsner
n-Nonanoyl-CC chemokine ligand 14, a potent CC chemokine ligand 14 analogue that prevents the recruitment of eosinophils in allergic airway inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3456-66.
2004: Sylvia Escher; Ulf Forssmann; Adjoa Frimpong-Boateng; Knut Adermann; Jalal Vakili; Heinrich Sticht; Michel detheux
Functional analysis of chemically synthesized derivatives of the human CC chemokine CCL15/HCC-2, a high affinity CCR1 ligand.
The journal of peptide research : official journal of the American Peptide Society 2004;63(1):36-47.
2002: Jan Münch; Ludger Ständker; Stefan Pöhlmann; Frédéric Baribaud; Armin Papkalla; Olaf Rosorius; Roland H Stauber; Gabriele Sass; Nikolaus Heveker; Knut Adermann; Sylvia Escher; Enno Klüver; Robert W Doms; Wolf-Georg Forssmann; Frank Kirchhoff
Hemofiltrate CC chemokine 1[9-74] causes effective internalization of CCR5 and is a potent inhibitor of R5-tropic human immunodeficiency virus type 1 strains in primary T cells and macrophages.
Antimicrobial agents and chemotherapy 2002;46(4):982-90.
2001: Ulf Forssmann; Hans-Jürgen Mägert; Knut Adermann; Sylvia Escher; Wolf-Georg Forssmann
Hemofiltrate CC chemokines with unique biochemical properties: HCC-1/CCL14a and HCC-2/CCL15.
Journal of leukocyte biology 2001;70(3):357-66.
1999: Sylvia Escher; Heinrich Sticht; Wolf-Georg Forssmann; Paul Rösch; Knut Adermann
Synthesis and characterization of the human CC chemokine HCC-2.
The journal of peptide research : official journal of the American Peptide Society 1999;54(6):505-13.
1999: Heinrich Sticht; Sylvia Escher; Kristian Schweimer; Wolf-Georg Forssmann; Paul Rösch; Knut Adermann
Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype.
Biochemistry 1999;38(19):5995-6002.
1998: Axel Schulz; Sylvia Escher; Ute C Marx; M Meyer; Paul Rösch; Wolf-Georg Forssmann; Knut Adermann
Carboxy-terminal extension stabilizes the topological stereoisomers of guanylin.
The journal of peptide research : official journal of the American Peptide Society 1998;52(6):518-25.