Terje Espevik

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Chemicals & Drugs

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Signal Transduction

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Palsson-McDermott Eva M; Doyle Sarah L; McGettrick Anne F; Hardy Matthew; Husebye Harald; Banahan Kathy; Gong Mei; Golenbock Douglas; Espevik Terje; O'Neill Luke A J
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Iversen Ann-Charlotte; Steinkjer Bjørg; Nilsen Nadra; Bohnhorst Janne; Moen Siv Helen; Vik Randi; Stephens Phil; Thomas David W; Benedict Chris A; Espevik Terje
A proviral role for CpG in cytomegalovirus infection.
Yndestad Arne; Landrø Linn; Ueland Thor; Dahl Christen P; Flo Trude H; Vinge Leif Erik; Espevik Terje; Frøland Stig S; Husberg Cathrine; Christensen Geir; Dickstein Kenneth; Kjekshus John; Øie Erik; Gullestad Lars; Aukrust Pål
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure.

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2009: Palsson-McDermott Eva M; Doyle Sarah L; McGettrick Anne F; Hardy Matthew; Husebye Harald; Banahan Kathy; Gong Mei; Golenbock Douglas; Espevik Terje; O'Neill Luke A J
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Nature immunology 2009;10(6):579-86.
2009: Iversen Ann-Charlotte; Steinkjer Bjørg; Nilsen Nadra; Bohnhorst Janne; Moen Siv Helen; Vik Randi; Stephens Phil; Thomas David W; Benedict Chris A; Espevik Terje
A proviral role for CpG in cytomegalovirus infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5672-81.
2009: Yndestad Arne; Landrø Linn; Ueland Thor; Dahl Christen P; Flo Trude H; Vinge Leif Erik; Espevik Terje; Frøland Stig S; Husberg Cathrine; Christensen Geir; Dickstein Kenneth; Kjekshus John; Øie Erik; Gullestad Lars; Aukrust Pål
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure.
European heart journal 2009;30(10):1229-36.
2009: Sandanger Øystein; Ryan Liv; Bohnhorst Janne; Iversen Ann-Charlotte; Husebye Harald; Halaas Øyvind; Landrø Linn; Aukrust Pål; Frøland Stig S; Elson Greg; Visintin Alberto; Øktedalen Olav; Damås Jan Kristian; Sundan Anders; Golenbock Douglas; Espevik Terje
IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):588-95.
2009: Damås Jan K; Davì Giovanni; Jensenius Mogens; Santilli Francesca; Otterdal Kari; Ueland Thor; Flo Trude H; Lien Egil; Espevik Terje; Frøland Stig S; Vitale Giustina; Raoult Didier; Aukrust Pål
Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever.
The Journal of infection 2009;58(1):68-75.
2008: Hellerud Bernt Christian; Stenvik Jørgen; Espevik Terje; Lambris John D; Mollnes Tom Eirik; Brandtzaeg Petter
Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation.
Infection and immunity 2008;76(9):4183-9.
2008: Nilsen Nadra J; Deininger Susanne; Nonstad Unni; Skjeldal Frode; Husebye Harald; Rodionov Dmitrii; von Aulock Sonja; Hartung Thomas; Lien Egil; Bakke Oddmund; Espevik Terje
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36.
Journal of leukocyte biology 2008;84(1):280-91.
2008: Mollnes Tom Eirik; Christiansen Dorte; Brekke Ole-Lars; Espevik Terje
Hypothesis: combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response.
Advances in experimental medicine and biology 2008;632():253-63.
2007: Latz Eicke; Verma Anjali; Visintin Alberto; Gong Mei; Sirois Cherilyn M; Klein Dionne C G; Monks Brian G; McKnight C James; Lamphier Marc S; Duprex W Paul; Espevik Terje; Golenbock Douglas T
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Nature immunology 2007;8(7):772-9.
2007: Tunheim Gro; Thompson Keith M; Fredriksen Agnete B; Espevik Terje; Schjetne Karoline W; Bogen Bjarne
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates.
Vaccine 2007;25(24):4723-34.
2007: Halaas Oyvind; Husebye Harald; Espevik Terje
The journey of Toll-like receptors in the cell.
Advances in experimental medicine and biology 2007;598():35-48.
2006: Ueland Thor; Espevik Terje; Kjekshus John; Gullestad Lars; Omland Torbjørn; Squire Iain B; Frøland Stig S; Mollnes Tom E; Dickstein Kenneth; Aukrust Pål
Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarction.
Journal of cardiac failure 2006;12(8):659-63.
2006: Rokstad Anne Mari; Donati Ivan; Borgogna Massimiliano; Oberholzer Josè; Strand Berit Løkensgard; Espevik Terje; Skjåk-Braek Gudmund
Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate.
Biomaterials 2006;27(27):4726-37.
2006: Johnsen Ingvild Bjellmo; Nguyen Thuy Thanh; Ringdal Monika; Tryggestad Anne Merete; Bakke Oddmund; Lien Egil; Espevik Terje; Anthonsen Marit W
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling.
The EMBO journal 2006;25(14):3335-46.
2006: Bohnhorst J; Rasmussen T; Moen S H; Fløttum M; Knudsen L; Børset M; Espevik T; Sundan A
Toll-like receptors mediate proliferation and survival of multiple myeloma cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(6):1138-44.
2006: Husebye Harald; Halaas Øyvind; Stenmark Harald; Tunheim Gro; Sandanger Øystein; Bogen Bjarne; Brech Andreas; Latz Eicke; Espevik Terje
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
The EMBO journal 2006;25(4):683-92.
2005: Heggelund L; Mollnes T E; Espevik T; Müller F; Kristiansen K I; Aukrust P; Frøland S S
Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection.
European journal of clinical investigation 2005;35(12):765-70.
2005: Mancuso Giuseppe; Midiri Angelina; Biondo Carmelo; Beninati Concetta; Gambuzza Maria; Macrì Daniele; Bellantoni Antonella; Weintraub Andrej; Espevik Terje; Teti Giuseppe
Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4.
Infection and immunity 2005;73(9):5620-7.
2005: Manukyan Maria; Triantafilou Kathy; Triantafilou Martha; Mackie Alan; Nilsen Nadra; Espevik Terje; Wiesmüller Karl-Heinz; Ulmer Artur J; Heine Holger
Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1.
European journal of immunology 2005;35(3):911-21.
2005: Dybdahl B; Slørdahl S A; Waage A; Kierulf P; Espevik T; Sundan A
Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction.
Heart (British Cardiac Society) 2005;91(3):299-304.
2004: Heggelund Lars; Flo Trude; Berg Kristin; Lien Egil; Mollnes Tom Eirik; Ueland Thor; Aukrust Pål; Espevik Terje; Frøland Stig S
Soluble toll-like receptor 2 in HIV infection: association with disease progression.
AIDS (London, England) 2004;18(18):2437-9.
2004: Heggelund L; Damås J K; Yndestad A; Holm A M; Muller F; Lien E; Espevik T; Aukrust P; Frøland S S
Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences.
Clinical and experimental immunology 2004;138(1):116-21.
2004: Nilsen Nadra; Nonstad Unni; Khan Naseema; Knetter Cathrine F; Akira Shizuo; Sundan Anders; Espevik Terje; Lien Egil
Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88.
The Journal of biological chemistry 2004;279(38):39727-35.
2004: Siedlar Maciej; Frankenberger Marion; Benkhart Elke; Espevik Terje; Quirling Martina; Brand Korbinian; Zembala Marek; Ziegler-Heitbrock Loems
Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(4):2736-45.
2004: Heggelund Lars; Müller Fredrik; Lien Egil; Yndestad Arne; Ueland Thor; Kristiansen Knut Ivan; Espevik Terje; Aukrust Pål; Frøland Stig S
Increased expression of toll-like receptor 2 on monocytes in HIV infection: possible roles in inflammation and viral replication.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;39(2):264-9.
2004: Halaas Ø; Liabakk N-B; Vik R; Beninati C; Henneke P; Sundan A; Espevik T
Monocytes stimulated with group B streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand.
Scandinavian journal of immunology 2004;60(1-2):74-81.
2004: Dybdahl Brit; Wahba Alexander; Haaverstad Rune; Kirkeby-Garstad Idar; Kierulf Peter; Espevik Terje; Sundan Anders
On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2004;25(6):985-92.
2004: Latz Eicke; Schoenemeyer Annett; Visintin Alberto; Fitzgerald Katherine A; Monks Brian G; Knetter Cathrine F; Lien Egil; Nilsen Nadra J; Espevik Terje; Golenbock Douglas T
TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Nature immunology 2004;5(2):190-8.
2004: Latz Eicke; Visintin Alberto; Espevik Terje; Golenbock Douglas T
Mechanisms of TLR9 activation.
Journal of endotoxin research 2004;10(6):406-12.
2004: Liabakk Nina-Beate; Espevik Terje
Monoclonal antibodies against TRAIL.
Vitamins and hormones 2004;67():65-79.
2003: Visintin Alberto; Latz Eicke; Monks Brian G; Espevik Terje; Golenbock Douglas T
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
The Journal of biological chemistry 2003;278(48):48313-20.
2003: Sandor Frantisek; Latz Eicke; Re Fabio; Mandell Leisa; Repik Galina; Golenbock Douglas T; Espevik Terje; Kurt-Jones Evelyn A; Finberg Robert W
Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
The Journal of cell biology 2003;162(6):1099-110.
2003: Schjetne Karoline W; Thompson Keith M; Nilsen Nadra; Flo Trude H; Fleckenstein Burkhard; Iversen Jens-Gustav; Espevik Terje; Bogen Bjarne
Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):32-6.
2003: Adib-Conquy Minou; Moine Pierre; Asehnoune Karim; Edouard Alain; Espevik Terje; Miyake Kensuke; Werts Catherine; Cavaillon Jean-Marc
Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation.
American journal of respiratory and critical care medicine 2003;168(2):158-64.
2003: Strand Berit L; Mørch Yrr A; Espevik Terje; Skjåk-Braek Gudmund
Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy.
Biotechnology and bioengineering 2003;82(4):386-94.
2003: Strand Berit L; Mørch Yrr A; Syvertsen Kjersti R; Espevik Terje; Skjåk-Braek Gudmund
Microcapsules made by enzymatically tailored alginate.
Journal of biomedical materials research. Part A 2003;64(3):540-50.
2003: Latz Eicke; Visintin Alberto; Lien Egil; Fitzgerald Kate A; Espevik Terje; Golenbock Douglas T
The LPS receptor generates inflammatory signals from the cell surface.
Journal of endotoxin research 2003;9(6):375-80.
2003: Espevik Terje; Latz Eicke; Lien Egil; Monks Brian; Golenbock Douglas T
Cell distributions and functions of Toll-like receptor 4 studied by fluorescent gene constructs.
Scandinavian journal of infectious diseases 2003;35(9):660-4.
2003: Rokstad A M; Strand B; Rian K; Steinkjer B; Kulseng B; Skjåk-Braek G; Espevik T
Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin.
Cell transplantation 2003;12(4):351-64.
2002: van der Kleij Desiree; Latz Eicke; Brouwers Jos F H M; Kruize Yvonne C M; Schmitz Marion; Kurt-Jones Evelyn A; Espevik Terje; de Jong Esther C; Kapsenberg Martien L; Golenbock Douglas T; Tielens Aloysius G M; Yazdanbakhsh Maria
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization.
The Journal of biological chemistry 2002;277(50):48122-9.
2002: Latz Eicke; Visintin Alberto; Lien Egil; Fitzgerald Kate A; Monks Brian G; Kurt-Jones Evelyn A; Golenbock Douglas T; Espevik Terje
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
The Journal of biological chemistry 2002;277(49):47834-43.
2002: Strand B L; Gåserød O; Kulseng B; Espevik T; Skjåk-Baek G
Alginate-polylysine-alginate microcapsules: effect of size reduction on capsule properties.
Journal of microencapsulation 2002;19(5):615-30.
2002: Flo Trude H; Ryan Liv; Latz Eicke; Takeuchi Osamu; Monks Brian G; Lien Egil; Halaas Øyvind; Akira Shizuo; Skjåk-Braek Gudmund; Golenbock Douglas T; Espevik Terje
Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
The Journal of biological chemistry 2002;277(38):35489-95.
2002: Ellingsen Espen; Morath Siegfried; Flo Trude; Schromm Andra; Hartung Thomas; Thiemermann Christoph; Espevik Terje; Golenbock Douglas; Foster Daniel; Solberg Rigmor; Aasen Ansgar; Wang Jacob
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(5):BR149-56.
2002: Belge Kai-Uwe; Dayyani Farshid; Horelt Alexia; Siedlar Maciej; Frankenberger Marion; Frankenberger Bernhard; Espevik Terje; Ziegler-Heitbrock Löms
The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3536-42.
2002: Tamai Riyoko; Sakuta Tetsuya; Matsushita Kenji; Torii Mitsuo; Takeuchi Osamu; Akira Shizuo; Akashi Sachiko; Espevik Terje; Sugawara Shunji; Takada Haruhiko
Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression.
Infection and immunity 2002;70(3):1272-8.
2002: Dybdahl Brit; Wahba Alexander; Lien Egil; Flo Trude H; Waage Anders; Qureshi Nilofer; Sellevold Olav F M; Espevik Terje; Sundan Anders
Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4.
Circulation 2002;105(6):685-90.
2002: Liabakk Nina Beate; Sundan Anders; Torp Sverre; Aukrust Pål; Frøland Stig S; Espevik Terje
Development, characterization and use of monoclonal antibodies against sTRAIL: measurement of sTRAIL by ELISA.
Journal of immunological methods 2002;259(1-2):119-28.
2002: Rokstad Anne Mari; Holtan Synnøve; Strand Berit; Steinkjer Bjørg; Ryan Liv; Kulseng Bård; Skjåk-Braek Gudmund; Espevik Terje
Microencapsulation of cells producing therapeutic proteins: optimizing cell growth and secretion.
Cell transplantation 2002;11(4):313-24.
2001: Henneke P; Takeuchi O; van Strijp J A; Guttormsen H K; Smith J A; Schromm A B; Espevik T A; Akira S; Nizet V; Kasper D L; Golenbock D T
Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):7069-76.
2001: Rokstad A M; Kulseng B; Strand B L; Skjåk-Braek G; Espevik T
Transplantation of alginate microcapsules with proliferating cells in mice: capsular overgrowth and survival of encapsulated cells of mice and human origin.
Annals of the New York Academy of Sciences 2001;944():216-25.
2001: Sugawara S; Yang S; Iki K; Hatakeyama J; Tamai R; Takeuchi O; Akashi S; Espevik T; Akira S; Takada H
Monocytic cell activation by Nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by toll-like receptor 2.
Infection and immunity 2001;69(8):4951-7.
2001: Wang J E; Warris A; Ellingsen E A; Jørgensen P F; Flo T H; Espevik T; Solberg R; Verweij P E; Aasen A O
Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae.
Infection and immunity 2001;69(4):2402-6.
2001: Flo T H; Halaas O; Torp S; Ryan L; Lien E; Dybdahl B; Sundan A; Espevik T
Differential expression of Toll-like receptor 2 in human cells.
Journal of leukocyte biology 2001;69(3):474-81.
2001: Strand B L; Ryan T L; In't Veld P; Kulseng B; Rokstad A M; Skjak-Brek G; Espevik T
Poly-L-Lysine induces fibrosis on alginate microcapsules via the induction of cytokines.
Cell transplantation 2001;10(3):263-75.
2000: Flo T H; Ryan L; Kilaas L; Skjâk-Braek G; Ingalls R R; Sundan A; Golenbock D T; Espevik T
Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Infection and immunity 2000;68(12):6770-6.
2000: Cuzzola M; Mancuso G; Beninati C; Biondo C; Genovese F; Tomasello F; Flo T H; Espevik T; Teti G
Beta 2 integrins are involved in cytokine responses to whole Gram-positive bacteria.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):5871-6.
2000: Halaas O; Vik R; Ashkenazi A; Espevik T
Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages.
Scandinavian journal of immunology 2000;51(3):244-50.
2000: Flo T H; Halaas O; Lien E; Ryan L; Teti G; Golenbock D T; Sundan A; Espevik T
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):2064-9.
2000: Cuzzola M; Mancuso G; Beninati C; Biondo C; von Hunolstein C; Orefici G; Espevik T; Flo T H; Teti G
Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products.
Infection and immunity 2000;68(2):994-8.
1999: Gullestad L; Aukrust P; Ueland T; Espevik T; Yee G; Vagelos R; Frøland S S; Fowler M
Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure.
Journal of the American College of Cardiology 1999;34(7):2061-7.
1999: Kulseng B; Espevik T; Skjåk-Braek G
[Treatment of diabetes mellitus with transplantation of immunoprotected pancreatic islet tissue]
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1999;119(28):4219-23.
1999: Børset M; Hjorth-Hansen H; Johnsen A C; Seidel C; Waage A; Espevik T; Sundan A
Apoptosis, proliferation and NF-kappaB activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor.
European journal of haematology 1999;63(5):345-53.
1999: Lien E; Sellati T J; Yoshimura A; Flo T H; Rawadi G; Finberg R W; Carroll J D; Espevik T; Ingalls R R; Radolf J D; Golenbock D T
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.
The Journal of biological chemistry 1999;274(47):33419-25.
1999: Johnsen A C; Haux J; Steinkjer B; Nonstad U; Egeberg K; Sundan A; Ashkenazi A; Espevik T
Regulation of APO-2 ligand/trail expression in NK cells-involvement in NK cell-mediated cytotoxicity.
Cytokine 1999;11(9):664-72.
1999: Heine H; Delude R L; Monks B G; Espevik T; Golenbock D T
Bacterial lipopolysaccharide induces expression of the stress response genes hop and H411.
The Journal of biological chemistry 1999;274(30):21049-55.
1999: Kulseng B; Vatten L; Espevik T
Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease.
Acta diabetologica 1999;36(1-2):99-105.
1999: Haux J; Johnsen A C; Steinkjer B; Egeberg K; Sundan A; Espevik T
The role of interleukin-2 in regulating the sensitivity of natural killer cells for Fas-mediated apoptosis.
Cancer immunology, immunotherapy : CII 1999;48(2-3):139-46.
1999: Kulseng B; Skjåk-Braek G; Ryan L; Andersson A; King A; Faxvaag A; Espevik T
Transplantation of alginate microcapsules: generation of antibodies against alginates and encapsulated porcine islet-like cell clusters.
Transplantation 1999;67(7):978-84.
1999: Aukrust P; Ueland T; Lien E; Bendtzen K; Müller F; Andreassen A K; Nordøy I; Aass H; Espevik T; Simonsen S; Frøland S S; Gullestad L
Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
The American journal of cardiology 1999;83(3):376-82.
1999: Aukrust P; Haug C J; Ueland T; Lien E; Müller F; Espevik T; Bollerslev J; Frøland S S
Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: indication of normalization of the bone-remodeling process during highly active antiretroviral therapy.
The Journal of clinical endocrinology and metabolism 1999;84(1):145-50.
1999: Aukrust P; Müller F; Lien E; Nordoy I; Liabakk N B; Kvale D; Espevik T; Froland S S
Tumor necrosis factor (TNF) system levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy: persistent TNF activation is associated with virologic and immunologic treatment failure.
The Journal of infectious diseases 1999;179(1):74-82.
1998: Ingalls R R; Monks B G; Savedra R; Christ W J; Delude R L; Medvedev A E; Espevik T; Golenbock D T
CD11/CD18 and CD14 share a common lipid A signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(10):5413-20.
1998: Thommesen L; Sjursen W; Gåsvik K; Hanssen W; Brekke O L; Skattebøl L; Holmeide A K; Espevik T; Johansen B; Laegreid A
Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3421-30.
1998: Lien E; Aukrust P; Sundan A; Müller F; Frøland S S; Espevik T
Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events.
Blood 1998;92(6):2084-92.
1998: Kulseng B; Børset M; Espevik T; Sundan A
Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus.
Acta diabetologica 1998;35(2):77-80.
1998: Berntzen G; Flo T H; Medvedev A; Kilaas L; Skjåk-Braek G; Sundan A; Espevik T
The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles.
Clinical and diagnostic laboratory immunology 1998;5(3):355-61.
1998: Medvedev A E; Flo T; Ingalls R R; Golenbock D T; Teti G; Vogel S N; Espevik T
Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4535-42.
1998: Halaas O; Vik R; Espevik T
Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4330-6.
1997: Jackson A M; Lien E; Alexandroff A B; Prescott S; Espevik T; James K; Selby P J; Sundan A
Soluble urinary CD14 after intravesical bacille Calmette-Guérin immunotherapy for carcinoma in situ.
British journal of urology 1997;80(5):766-71.
1997: Halaas O; Olsen W M; Veiby O P; Løvhaug D; Skjåk-Braek G; Vik R; Espevik T
Mannuronan enhances survival of lethally irradiated mice and stimulates murine haematopoiesis in vitro.
Scandinavian journal of immunology 1997;46(4):358-65.
1997: Aukrust P; Hestdal K; Lien E; Bjerkeli V; Nordøy I; Espevik T; Müller F; Frøland S S
Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-alpha activity in human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 1997;176(4):913-23.
1997: Hestdal K; Aukrust P; Müller F; Lien E; Bjerkeli V; Espevik T; Frøland S S
Dysregulation of membrane-bound tumor necrosis factor-alpha and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection: low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load.
Blood 1997;90(7):2670-9.
1997: Kulseng B; Thu B; Espevik T; Skjåk-Braek G
Alginate polylysine microcapsules as immune barrier: permeability of cytokines and immunoglobulins over the capsule membrane.
Cell transplantation 1997;6(4):387-94.
1997: Sandler S; Andersson A; Eizirik D L; Hellerström C; Espevik T; Kulseng B; Thu B; Pipeleers D G; Skjåk-Braek G
Assessment of insulin secretion in vitro from microencapsulated fetal porcine islet-like cell clusters and rat, mouse, and human pancreatic islets.
Transplantation 1997;63(12):1712-8.
1997: Medvedev A E; Johnsen A C; Haux J; Steinkjer B; Egeberg K; Lynch D H; Sundan A; Espevik T
Regulation of Fas and Fas-ligand expression in NK cells by cytokines and the involvement of Fas-ligand in NK/LAK cell-mediated cytotoxicity.
Cytokine 1997;9(6):394-404.
1997: Jahr T G; Ryan L; Sundan A; Lichenstein H S; Skjåk-Braek G; Espevik T
Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/permeability-increasing factor.
Infection and immunity 1997;65(1):89-94.
1996: Borset M; Lien E; Espevik T; Helseth E; Waage A; Sundan A
Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines.
The Journal of biological chemistry 1996;271(40):24655-61.
1996: Börset M; Medvedev A E; Sundan A; Espevik T
The role of the two TNF receptors in proliferation, NF-kappa B activation and discrimination between TNF and LT alpha signalling in the human myeloma cell line OH-2.
Cytokine 1996;8(6):430-8.
1996: Thu B; Bruheim P; Espevik T; Smidsrød O; Soon-Shiong P; Skjåk-Braek G
Alginate polycation microcapsules. II. Some functional properties.
Biomaterials 1996;17(11):1069-79.
1996: Thu B; Bruheim P; Espevik T; Smidsrød O; Soon-Shiong P; Skjåk-Braek G
Alginate polycation microcapsules. I. Interaction between alginate and polycation.
Biomaterials 1996;17(10):1031-40.
1996: Medvedev A E; Laegreid A; Sundan A; Espevik T
A non-competitive P55 TNF receptor antibody enhances the specific activity of lymphotoxin-alpha.
Scandinavian journal of immunology 1996;43(4):439-48.
1996: Medvedev A E; Espevik T; Ranges G; Sundan A
Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin alpha effects.
The Journal of biological chemistry 1996;271(16):9778-84.
1996: Kulseng B; Skjåk-Braek G; Følling I; Espevik T
TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide.
Scandinavian journal of immunology 1996;43(3):335-40.
1996: Aukrust P; Lien E; Kristoffersen A K; Müller F; Haug C J; Espevik T; Frøland S S
Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency--possible immunologic and clinical consequences.
Blood 1996;87(2):674-81.
1996: Haug C J; Aukrust P; Lien E; Müller F; Espevik T; Frøland S S
Disseminated Mycobacterium avium complex infection in AIDS: immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D.
The Journal of infectious diseases 1996;173(1):259-62.
1995: Faxvaag A; Espevik T; Dalen A
An immunosuppressive murine leukaemia virus induces a Th1-->Th2 switch and abrogates the IgM antibody response to sheep erythrocytes by suppressing the production of IL-2.
Clinical and experimental immunology 1995;102(3):487-95.
1995: Laegreid A; Thommesen L; Jahr T G; Sundan A; Espevik T
Tumor necrosis factor induces lipopolysaccharide tolerance in a human adenocarcinoma cell line mainly through the TNF p55 receptor.
The Journal of biological chemistry 1995;270(43):25418-25.
1995: Arntzen K J; Liabakk N B; Jacobsen G; Espevik T; Austgulen R
Soluble tumor necrosis factor receptor in serum and urine throughout normal pregnancy and at delivery.
American journal of reproductive immunology (New York, N.Y. : 1989) 1995;34(3):163-9.
1995: Lien E; Liabakk N B; Johnsen A C; Nonstad U; Sundan A; Espevik T
Polymorphonuclear granulocytes enhance lipopolysaccharide-induced soluble p75 tumor necrosis factor receptor release from mononuclear cells.
European journal of immunology 1995;25(9):2714-7.
1995: Jahr T G; Sundan A; Lichenstein H S; Espevik T
Influence of CD14, LBP and BPI in the monocyte response to LPS of different polysaccharide chain length.
Scandinavian journal of immunology 1995;42(1):119-27.
1995: Otterlei M; Sundan A; Ryan L; Espevik T
Effects of anti-CD18 and LPS on CD14 expression on human monocytes.
Scandinavian journal of immunology 1995;41(6):583-92.
1995: Aukrust P; Liabakk N B; Müller F; Espevik T; Frøland S S
Activation of tumor necrosis factor--alpha system in HIV-1 infection: association with markers of immune activation.
Infection 1995;23(1):9-15.
1994: Medvedev A E; Sundan A; Espevik T
Involvement of the tumor necrosis factor receptor p75 in mediating cytotoxicity and gene regulating activities.
European journal of immunology 1994;24(11):2842-9.
1994: Aukrust P; Frøland S S; Liabakk N B; Müller F; Nordøy I; Haug C; Espevik T
Release of cytokines, soluble cytokine receptors, and interleukin-1 receptor antagonist after intravenous immunoglobulin administration in vivo.
Blood 1994;84(7):2136-43.
1994: Halgunset J; Johnsen H; Kjøllesdal A M; Qvigstad E; Espevik T; Austgulen R
Cytokine levels in amniotic fluid and inflammatory changes in the placenta from normal deliveries at term.
European journal of obstetrics, gynecology, and reproductive biology 1994;56(3):153-60.
1994: Sundan A; Gullstein-Jahr T; Otterlei M; Ryan L; Bazil V; Wright S D; Espevik T
Soluble CD14 from urine copurifies with a potent inducer of cytokines.
European journal of immunology 1994;24(8):1779-84.
1994: Otterlei M; Vårum K M; Ryan L; Espevik T
Characterization of binding and TNF-alpha-inducing ability of chitosans on monocytes: the involvement of CD14.
Vaccine 1994;12(9):825-32.
1994: Laegreid A; Medvedev A; Nonstad U; Bombara M P; Ranges G; Sundan A; Espevik T
Tumor necrosis factor receptor p75 mediates cell-specific activation of nuclear factor kappa B and induction of human cytomegalovirus enhancer.
The Journal of biological chemistry 1994;269(10):7785-91.
1994: Waage A; Espevik T
TNF receptors in chronic lymphocytic leukemia.
Leukemia & lymphoma 1994;13(1-2):41-6.
1994: Brekke O L; Espevik T; Bjerve K S
Butylated hydroxyanisole inhibits tumor necrosis factor-induced cytotoxicity and arachidonic acid release.
Lipids 1994;29(2):91-102.
1994: Aukrust P; Liabakk N B; Müller F; Lien E; Espevik T; Frøland S S
Serum levels of tumor necrosis factor-alpha (TNF alpha) and soluble TNF receptors in human immunodeficiency virus type 1 infection--correlations to clinical, immunologic, and virologic parameters.
The Journal of infectious diseases 1994;169(2):420-4.
1993: Liabakk N B; Lien E; Sundan A; Sunde A; Austgulen R; Espevik T
High concentrations of the soluble p55 tumour necrosis factor receptor in human seminal plasma.
Human reproduction (Oxford, England) 1993;8(11):1837-42.
1993: Austgulen R; Johnsen H; Kjøllesdal A M; Liabakk N B; Espevik T
Soluble receptors for tumor necrosis factor: occurrence in association with normal delivery at term.
Obstetrics and gynecology 1993;82(3):343-7.
1993: Faxvaag A; Espevik T; Dalen A
Multiple derangements of cytokine homeostasis in mice infected with immunosuppressive retrovirus.
Cellular immunology 1993;150(2):247-56.
1993: Liabakk N B; Sundan A; Lien E; Laegreid A; Bombara M P; Ranges G; Espevik T
The release of soluble p55 TNF receptor from U937 cells studied by a new p55 immunoassay.
Journal of immunological methods 1993;163(2):145-54.
1993: Naume B; Johnsen A C; Espevik T; Sundan A
Gene expression and secretion of cytokines and cytokine receptors from highly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12.
European journal of immunology 1993;23(8):1831-8.
1993: Otterlei M; Sundan A; Skjåk-Braek G; Ryan L; Smidsrød O; Espevik T
Similar mechanisms of action of defined polysaccharides and lipopolysaccharides: characterization of binding and tumor necrosis factor alpha induction.
Infection and immunity 1993;61(5):1917-25.
1993: Austgulen R; Liabakk N B; Lien E; Espevik T
Increased levels of soluble tumor necrosis factor-alpha receptors in serum from pregnant women and in serum and urine samples from newborns.
Pediatric research 1993;33(1):82-7.
1993: Naume B; Gately M K; Desai B B; Sundan A; Espevik T
Synergistic effects of interleukin 4 and interleukin 12 on NK cell proliferation.
Cytokine 1993;5(1):38-46.
1993: Espevik T; Otterlei M; Skjåk-Braek G; Ryan L; Wright S D; Sundan A
The involvement of CD14 in stimulation of cytokine production by uronic acid polymers.
European journal of immunology 1993;23(1):255-61.
1992: Frey E A; Miller D S; Jahr T G; Sundan A; Bazil V; Espevik T; Finlay B B; Wright S D
Soluble CD14 participates in the response of cells to lipopolysaccharide.
The Journal of experimental medicine 1992;176(6):1665-71.
1992: Waage A; Liabakk N; Lien E; Lamvik J; Espevik T
p55 and p75 tumor necrosis factor receptors in patients with chronic lymphocytic leukemia.
Blood 1992;80(10):2577-83.
1992: Austgulen R; Liabakk N B; Espevik T
[Secretion of soluble receptors for tumor necrosis factor. An immunologic buffer mechanism during normal pregnancy?]
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1992;112(28):3545-7.
1992: Galloway C J; Madanat M S; Sarr T; Espevik T; Dumas M L; Mitra G; Ranges G E
Anti-tumor necrosis factor receptor and tumor necrosis factor agonist activity by an anti-idiotypic antibody.
European journal of immunology 1992;22(11):3045-8.
1992: Austgulen R; Espevik T; Mecsei R; Scott H
Expression of receptors for tumor necrosis factor in human placenta at term.
Acta obstetricia et gynecologica Scandinavica 1992;71(6):417-24.
1992: Austgulen R; Liabakk N B; Brockhaus M; Espevik T
Soluble TNF receptors in amniotic fluid and in urine from pregnant women.
Journal of reproductive immunology 1992;22(2):105-16.
1992: Brekke O L; Shalaby M R; Sundan A; Espevik T; Bjerve K S
Butylated hydroxyanisole specifically inhibits tumor necrosis factor-induced cytotoxicity and growth enhancement.
Cytokine 1992;4(4):269-80.
1992: Naume B; Gately M; Espevik T
A comparative study of IL-12 (cytotoxic lymphocyte maturation factor)-, IL-2-, and IL-7-induced effects on immunomagnetically purified CD56+ NK cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(8):2429-36.
1992: Brekke O L; Espevik T; Bardal T; Bjerve K S
Effects of n-3 and n-6 fatty acids on tumor necrosis factor cytotoxicity in WEHI fibrosarcoma cells.
Lipids 1992;27(3):161-8.
1991: Naume B; Espevik T
Effects of IL-7 and IL-2 on highly enriched CD56+ natural killer cells. A comparative study.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(7):2208-14.
1991: Otterlei M; Ostgaard K; Skjåk-Braek G; Smidsrød O; Soon-Shiong P; Espevik T
Induction of cytokine production from human monocytes stimulated with alginate.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1991;10(4):286-91.
1991: Liabakk N B; Sundan A; Waage A; Brockhaus M; Loetcher H; Lesslauer W; Espevik T
Development of immunoassays for the detection of soluble tumour necrosis factor receptors.
Journal of immunological methods 1991;141(2):237-43.
1991: Naume B; Shalaby R; Lesslauer W; Espevik T
Involvement of the 55- and 75-kDa tumor necrosis factor receptors in the generation of lymphokine-activated killer cell activity and proliferation of natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(9):3045-8.
1991: Naume B; Nonstad U; Steinkjer B; Funderud S; Smeland E; Espevik T
Immunomagnetic isolation of NK and LAK cells.
Journal of immunological methods 1991;136(1):1-9.
1990: Shalaby M R; Sundan A; Loetscher H; Brockhaus M; Lesslauer W; Espevik T
Binding and regulation of cellular functions by monoclonal antibodies against human tumor necrosis factor receptors.
The Journal of experimental medicine 1990;172(5):1517-20.
1990: Espevik T; Waage A; Faxvaag A; Shalaby M R
Regulation of interleukin-2 and interleukin-6 production from T-cells: involvement of interleukin-1 beta and transforming growth factor-beta.
Cellular immunology 1990;126(1):47-56.
1990: Espevik T; Brockhaus M; Loetscher H; Nonstad U; Shalaby R
Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor.
The Journal of experimental medicine 1990;171(2):415-26.
1990: Espevik T; Shalaby R; Liabakk N B; Waage A; Sundan A
The role of TNF in regulation of cell function.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1990;202():160.
1989: Shalaby M R; Waage A; Aarden L; Espevik T
Endotoxin, tumor necrosis factor-alpha and interleukin 1 induce interleukin 6 production in vivo.
Clinical immunology and immunopathology 1989;53(3):488-98.
1989: Waage A; Halstensen A; Shalaby R; Brandtzaeg P; Kierulf P; Espevik T
Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response.
The Journal of experimental medicine 1989;170(6):1859-67.
1989: Hofsli E; Bakke O; Nonstad U; Espevik T
A flow cytometric and immunofluorescence microscopic study of tumor necrosis factor production and localization in human monocytes.
Cellular immunology 1989;122(2):405-15.
1989: Shalaby M R; Waage A; Espevik T
Cytokine regulation of interleukin 6 production by human endothelial cells.
Cellular immunology 1989;121(2):372-82.
1989: Waage A; Kaufmann C; Espevik T; Husby G
Interleukin-6 in synovial fluid from patients with arthritis.
Clinical immunology and immunopathology 1989;50(3):394-8.
1989: Waage A; Brandtzaeg P; Halstensen A; Kierulf P; Espevik T
The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.
The Journal of experimental medicine 1989;169(1):333-8.
1988: Nissen-Meyer J; Austgulen R; Espevik T
Synergistic growth-inhibitory activity of tumour necrosis factor and alpha interferon. Contribution to the monocyte-derived cytostatic activity towards human leukaemia K562 cells.
Scandinavian journal of immunology 1988;28(5):627-37.
1988: Shalaby M R; Espevik T; Rice G C; Ammann A J; Figari I S; Ranges G E; Palladino M A
The involvement of human tumor necrosis factors-alpha and -beta in the mixed lymphocyte reaction.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(2):499-503.
1988: Ranges G E; Zlotnik A; Espevik T; Dinarello C A; Cerami A; Palladino M A
Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.
The Journal of experimental medicine 1988;167(4):1472-8.
1988: Espevik T; Figari I S; Ranges G E; Palladino M A
Transforming growth factor-beta 1 (TGF-beta 1) and recombinant human tumor necrosis factor-alpha reciprocally regulate the generation of lymphokine-activated killer cell activity. Comparison between natural porcine platelet-derived TGF-beta 1 and TGF-beta 2, and recombinant human TGF-beta 1.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2312-6.
1988: Nissen-Meyer J; Hofsli E; Espevik T; Austgulen R
Involvement of tumor necrosis factor in cytotoxicity mediated by human monocytes.
Natural immunity and cell growth regulation 1988;7(5-6):266-79.
1987: Austgulen R; Espevik T; Nissen-Meyer J
Fibroblast growth-stimulatory activity released from human monocytes. The contribution of tumour necrosis factor.
Scandinavian journal of immunology 1987;26(6):621-9.
1987: Ranges G E; Figari I S; Espevik T; Palladino M A
Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha.
The Journal of experimental medicine 1987;166(4):991-8.
1987: Nissen-Meyer J; Espevik T
Effect of antisera against recombinant tumor necrosis factor and the monocyte-derived cytotoxin(s) on monocyte-mediated killing of various tumor cells.
Cellular immunology 1987;109(2):384-96.
1987: Espevik T; Nissen-Meyer J
Tumour necrosis factor-like activity on paraformaldehyde-fixed monocyte monolayers.
Immunology 1987;61(4):443-8.
1987: Austgulen R; Nissen-Meyer J; Degré M; Espevik T
Monocyte-derived influence on growth of normal human fibroblasts. The contribution of tumour necrosis factor to growth inhibition.
Scandinavian journal of immunology 1987;26(2):175-85.
1987: Espevik T; Figari I S; Shalaby M R; Lackides G A; Lewis G D; Shepard H M; Palladino M A
Inhibition of cytokine production by cyclosporin A and transforming growth factor beta.
The Journal of experimental medicine 1987;166(2):571-6.

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