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Antonio Espinosa

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M Dora Carrión; Mariem Chayah; Duane Choquesillo-Lazarte; Antonio Entrena; Antonio Espinosa; Miguel A Gallo; LUISA-CARLOTA LÓPEZ-CARA; M Encarnación Camacho
NMR spectroscopic characterization of new 2,3-dihydro-1,3,4-thiadiazole derivatives.
Belén Rubio-Ruiz; Ana Conejo-García; Antonio Espinosa; Miguel A Gallo; Antonio Entrena
1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety.
M Encarnación Camacho; M D Carrion; Antonio Entrena; Germaine Escames; Antonio Espinosa; Miguel A Gallo; L C Lopez-Cara; Dario Acuna-Castroviejo
Melatonin synthetic analogs as nitric oxide synthase inhibitors.

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2012: M Dora Carrión; Mariem Chayah; Duane Choquesillo-Lazarte; Antonio Entrena; Antonio Espinosa; Miguel A Gallo; LUISA-CARLOTA LÓPEZ-CARA; M Encarnación Camacho
NMR spectroscopic characterization of new 2,3-dihydro-1,3,4-thiadiazole derivatives.
Magnetic resonance in chemistry : MRC 2012;50(7):515-22.
2012: Belén Rubio-Ruiz; Ana Conejo-García; Antonio Espinosa; Miguel A Gallo; Antonio Entrena
1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety.
Magnetic resonance in chemistry : MRC 2012;50(6):466-9.
2012: M Encarnación Camacho; M D Carrion; Antonio Entrena; Germaine Escames; Antonio Espinosa; Miguel A Gallo; L C Lopez-Cara; Dario Acuna-Castroviejo
Melatonin synthetic analogs as nitric oxide synthase inhibitors.
Mini reviews in medicinal chemistry 2012;12(7):600-17.
2012: Belén Rubio-Ruíz; Josefa Segovia; María Paz Carrasco-Jiménez; Ana Conejo-García; Antonio Espinosa; Miguel A Gallo; Carmen Marco; Pablo Ríos-Marco; Antonio Entrena
Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors.
European journal of medicinal chemistry 2012;50():154-62.
2012: LUISA-CARLOTA LÓPEZ-CARA; Darío Acuña-Castroviejo; M Dora Carrión; Antonio Entrena; Germaine Escames; Antonio Espinosa; Miguel A Gallo; Ana López; M Encarnación Camacho
1,3,4-Thiadiazole derivatives as selective inhibitors of iNOS versus nNOS: Synthesis and structure-activity dependence.
European journal of medicinal chemistry 2012;50():129-39.
2012: M Dora Carrión; Mariem Chayah; Duane Choquesillo-Lazarte; Antonio Entrena; Antonio Espinosa; Miguel A Gallo; M Encarnación Camacho
Characterization of 4,5-dihydro-1H-pyrazole derivatives by (13) C NMR spectroscopy.
Magnetic resonance in chemistry : MRC 2012;50(1):58-61.
2011: Darío Acuña-Castroviejo; Victor Tapias; Luis Lopez; Carolina Doerrier; Encarnación Camacho; María D Carrión; Francisco Mora; Antonio Espinosa; Germaine Escames
Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Brain research bulletin 2011;85(3-4):133-40.
2011: Ana Conejo-García; Antonio Espinosa; Miguel A Gallo; Francesco Leonetti; Orazio Nicolotti; Maria del Carmen Núñez; Leonardo Pisani; Joaquín M Campos; Marco Catto; Angelo Carotti
Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity.
Journal of medicinal chemistry 2011;54(8):2627-45.
2009: LUISA-CARLOTA LÓPEZ-CARA; M José Pineda de las Infantas; María Dora Carrión; M Encarnación Camacho; Miguel A Gallo; Antonio Espinosa; Antonio Entrena
NMR and conformational studies of new 5-phenylpyrrole-carboxamide derivatives.
Magnetic resonance in chemistry : MRC 2009;47(12):1101-9.
2009: Victor Tapias; Germaine Escames; Luis Lopez; Ana López; Encarnación Camacho; María D Carrión; Antonio Entrena; Miguel A Gallo; Antonio Espinosa; Darío Acuña-Castroviejo
Melatonin and its brain metabolite N(1)-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice.
Journal of neuroscience research 2009;87(13):3002-10.
2009: LUISA-CARLOTA LÓPEZ-CARA; M Encarnación Camacho; María Dora Carrión; Victor Tapias; Miguel A Gallo; Germaine Escames; Darío Acuña-Castroviejo; Antonio Espinosa; Antonio Entrena
Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.
European journal of medicinal chemistry 2009;44(6):2655-66.
2009: María C Núñez; M Eugenia García-Rubiño; Ana Conejo-García; Olga Cruz-López; María Kimatrai; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Homochiral drugs: a demanding tendency of the pharmaceutical industry.
Current medicinal chemistry 2009;16(16):2064-74.
2009: Juan A Marchal; María C Núñez; Antonia Aránega; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Acyclonucleosides, modified seco-nucleosides, and salicyl- or catechol-derived acyclic 5-fluorouracil O,N-acetals: antiproliferative activities, cellular differentiation and apoptosis.
Current medicinal chemistry 2009;16(9):1166-83.
2008: María Dora Carrión; LUISA-CARLOTA LÓPEZ-CARA; M Encarnación Camacho; Victor Tapias; Germaine Escames; Darío Acuña-Castroviejo; Antonio Espinosa; Miguel A Gallo; Antonio Entrena
Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III).
European journal of medicinal chemistry 2008;43(11):2579-91.
2008: Ana Conejo-García; Olga Cruz-López; Mónica Díaz-Gavilán; Antonio Espinosa; Miguel Ángel Gallo; María Del Carmen Núñez; Joaquín M Campos
From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: the shift from differentiating anticancer agents to apoptotic inducers.
Expert opinion on drug discovery 2008;3(10):1223-35.
2008: LUISA-CARLOTA LÓPEZ-CARA; María Dora Carrión; M Encarnación Camacho; Miguel A Gallo; Antonio Espinosa; Duane Choquesillo-Lazarte; Josefa M Gonzalez-Pérez; Antonio Entrena-Guadix
1H, 13C NMR, X-ray and conformational studies of new 1-alkyl-3-benzoyl-pyrazole and 1-alkyl-3-benzoyl-pyrazoline derivatives.
Magnetic resonance in chemistry : MRC 2008;46(9):878-85.
2008: Ana Conejo-García; María C Núñez; Juan A Marchal; Fernando Rodríguez-Serrano; Antonia Aránega; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines.
European journal of medicinal chemistry 2008;43(8):1742-8.
2008: Mónica Díaz-Gavilán; José A Gómez-Vidal; Fernando Rodríguez-Serrano; Juan A Marchal; Octavio Caba; Antonia Aránega; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies.
Bioorganic & medicinal chemistry letters 2008;18(4):1457-60.
2008: María C Núñez; Mónica Díaz-Gavilán; Ana Conejo-García; Olga Cruz-López; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines.
Current medicinal chemistry 2008;15(25):2614-31.
2008: Mónica Díaz-Gavilán; Ana Conejo-García; Olga Cruz-López; María C Núñez; Duane Choquesillo-Lazarte; Josefa M González-Pérez; Fernando Rodríguez-Serrano; Juan A Marchal; Antonia Aránega; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin-3-ylmethyl)-9H-purines.
ChemMedChem 2008;3(1):127-35.
2007: Juan A Marchal; Fernando Rodríguez-Serrano; Octavio Caba; Antonia Aránega; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells.
ChemMedChem 2007;2(12):1814-21.
2007: Juan A Marchal; María C Núñez; Inés Suárez; Mónica Díaz-Gavilán; José A Gómez-Vidal; Houria Boulaiz; Fernando Rodríguez-Serrano; Miguel A Gallo; Antonio Espinosa; Antonia Aránega; Joaquín M Campos
A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells.
Breast cancer research and treatment 2007;105(3):237-46.
2007: Ana García-Navarro; Cristina González-Puga; Germaine Escames; Luis Lopez; Ana López; Manuel López-Cantarero; Encarnación Camacho; Antonio Espinosa; Miguel A Gallo; Darío Acuña-Castroviejo
Cellular mechanisms involved in the melatonin inhibition of HT-29 human colon cancer cell proliferation in culture.
Journal of pineal research 2007;43(2):195-205.
2007: Juan A Marchal; Houria Boulaiz; Fernando Rodríguez-Serrano; Macarena Peran; Esmeralda Carrillo; Celia Vélez; José Domínguez; José A Gómez-Vidal; Joaquín Campos; Miguel A Gallo; Antonio Espinosa; Antonia Aránega
5-fluorouracil derivatives induce differentiation mediated by tubulin and HLA class I modulation.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2007;3(3):233-9.
2007: Olga Cruz-López; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
1H and 13C NMR studies of 2-functionalized 5-(methylsulfonyl)-1-phenyl-1H-indoles.
Magnetic resonance in chemistry : MRC 2007;45(2):185-8.
2007: Olga Cruz-López; Juan J Díaz-Mochón; Joaquín M Campos; Antonio Entrena; María T Núñez; LUIS LABEAGA; Aurelio Orjales; Miguel A Gallo; Antonio Espinosa
Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: potent and selective in vitro cyclooxygenase-2 inhibitors.
ChemMedChem 2007;2(1):88-100.
2006: Visitación Gallardo; M Adolfina Ruiz; E Morales; J Zouaki; Joaquín Campos; Ana Conejo-García; Miguel A Gallo; Antonio Espinosa
Characterization of latex-antineoplastic drug complexes by differential scanning calorimetry and microphotography.
Die Pharmazie 2006;61(12):1009-13.
2006: Lara Milanese; Antonio Espinosa; Joaquín M Campos; Miguel A Gallo; Antonio Entrena
Insight into the inhibition of human choline kinase: homology modeling and molecular dynamics simulations.
ChemMedChem 2006;1(11):1216-28.
2006: Josefa León; Germaine Escames; María I Rodríguez; Luis Lopez; Victor Tapias; Antonio Entrena; Encarnación Camacho; María Dora Carrión; Miguel A Gallo; Antonio Espinosa; Dun-Xian Tan; Russel J Reiter; Darío Acuña-Castroviejo
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin.
Journal of neurochemistry 2006;98(6):2023-33.
2006: Mónica Díaz-Gavilán; José A Gómez-Vidal; Antonio Entrena; Miguel A Gallo; Antonio Espinosa; Joaquín M Campos
Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom.
The Journal of organic chemistry 2006;71(3):1043-54.
2006: Joaquín M Campos; Rosario M Sánchez-Martín; Ana Conejo-García; Antonio Entrena; Miguel A Gallo; Antonio Espinosa
(Q)SAR studies to design new human choline kinase inhibitors as antiproliferative drugs.
Current medicinal chemistry 2006;13(11):1231-48.
2005: Antonio Entrena; M Encarnación Camacho; María Dora Carrión; LUISA-CARLOTA LÓPEZ-CARA; Guillermo Velasco; Josefa León; Germaine Escames; Darío Acuña-Castroviejo; Victor Tapias; Miguel A Gallo; Antonio Vivó; Antonio Espinosa
Kynurenamines as neural nitric oxide synthase inhibitors.
Journal of medicinal chemistry 2005;48(26):8174-81.
2005: Joaquín M Campos; Rosario M Sánchez-Martín; Olga Cruz-López; Ana Conejo-García; Miguel A Gallo; Antonio Espinosa
1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives.
Magnetic resonance in chemistry : MRC 2005;43(12):1066-71.
2005: María Dora Carrión; LUISA-CARLOTA LÓPEZ-CARA; M Encarnación Camacho; Antonio Entrena; Miguel A Gallo; Antonio Espinosa
Structural elucidation of a new delta2-pyrazoline derivatives using 1H and 13C NMR spectroscopy.
Magnetic resonance in chemistry : MRC 2005;43(12):1063-5.
2005: Ana Conejo-García; Joaquín Campos; Carmen Eder; Antonio Entrena; Miguel A Gallo; Antonio Espinosa
Synthesis and NMR studies on a C3-symmetrical triquinolina triscationic bicyclophane.
The Journal of organic chemistry 2005;70(14):5748-51.
2005: Rosario M Sánchez-Martín; Joaquín M Campos; Ana Conejo-García; Olga Cruz-López; Mónica Báñez-Coronel; Agustín Rodríguez-González; Miguel A Gallo; Juan Carlos Lacal; Antonio Espinosa
Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.
Journal of medicinal chemistry 2005;48(9):3354-63.
2005: Asier Unciti-Broceta; Maria J Pineda-de-las-Infantas; Juan J Díaz-Mochón; Romeo Romagnoli; Pier G Baraldi; Miguel A Gallo; Antonio Espinosa
Regioselective one-pot synthesis of 9-alkyl-6-chloropyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazines. Reactivity of aliphatic and aromatic hydrazides.
The Journal of organic chemistry 2005;70(7):2878-80.
2005: Ana Conejo-García; Antonio Entrena; Joaquín M Campos; Rosario M Sánchez-Martín; Miguel A Gallo; Antonio Espinosa
Towards a model for the inhibition of choline kinase by a new type of inhibitor.
European journal of medicinal chemistry 2005;40(3):315-9.
2005: Antonio Espinosa; Juan A Marchal; Antonia Aránega; Miguel A Gallo; Stefania Aiello; Joaquín Campos
Antitumoural properties of benzannelated seven-membered 5-fluorouracil derivatives and related open analogues. Molecular markers for apoptosis and cell cycle dysregulation.
Farmaco (Società chimica italiana : 1989) 2005;60(2):91-7.
2005: Joaquín Campos; Estrella Saniger; Juan A Marchal; Stefania Aiello; Inés Súarez; Houria Boulaiz; Antonia Aránega; Miguel A Gallo; Antonio Espinosa
New medium oxacyclic O,N-acetals and related open analogues: biological activities.
Current medicinal chemistry 2005;12(12):1423-38.
2004: M Encarnación Camacho; Josefa León; Antonio Entrena; Guillermo Velasco; María Dora Carrión; Germaine Escames; Antonio Vivó; Darío Acuña-Castroviejo; Miguel A Gallo; Antonio Espinosa
4,5-dihydro-1H-pyrazole derivatives with inhibitory nNOS activity in rat brain: synthesis and structure-activity relationships.
Journal of medicinal chemistry 2004;47(23):5641-50.
2004: Juan A Marchal; Houria Boulaiz; Inés Suárez; Estrella Saniger; Joaquín Campos; Esmeralda Carrillo; José Prados; Miguel A Gallo; Antonio Espinosa; Antonia Aránega
Growth inhibition, G(1)-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives.
Investigational new drugs 2004;22(4):379-89.
2004: Ana Conejo-García; Mónica Báñez-Coronel; Rosario M Sánchez-Martín; Agustín Rodríguez-González; Angeles Ramos; Ana Ramírez de Molina; Antonio Espinosa; Miguel A Gallo; Joaquín M Campos; Juan Carlos Lacal
Influence of the linker in bispyridium compounds on the inhibition of human choline kinase.
Journal of medicinal chemistry 2004;47(22):5433-40.
2004: Pier Giovanni Baraldi; Italo Beria; Paolo Cozzi; Cristina Geroni; Antonio Espinosa; Miguel A Gallo; Antonio Entrena; John P Bingham; John A Hartley; LUISA-CARLOTA LÓPEZ-CARA
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies.
Bioorganic & medicinal chemistry 2004;12(14):3911-21.
2004: Leila Bikjdaouene; Germaine Escames; Encarnación Camacho; Josefa León; José M R Ferrer; Antonio Espinosa; Miguel A Gallo; Juan de Dios Luna; Darío Acuña-Castroviejo
Effects of some synthetic kynurenines on brain amino acids and nitric oxide after pentylenetetrazole administration to rats.
Journal of pineal research 2004;36(4):267-77.
2004: Pier Giovanni Baraldi; Maria del Carmen Nûnez; Antonio Espinosa; LUISA-CARLOTA LÓPEZ-CARA
Distamycin A as stem of DNA minor groove alkylating agents.
Current topics in medicinal chemistry 2004;4(2):231-9.
2004: José A Gómez-Vidal; Joaquín Campos; Juan A Marchal; Houria Boulaiz; Miguel A Gallo; Esmeralda Carrillo; Antonio Espinosa; Antonia Aránega
Actual targets in cytodifferentiation cancer therapy.
Current topics in medicinal chemistry 2004;4(2):175-202.
2003: Ana Conejo-García; Joaquín M Campos; Antonio Entrena; Rosario M Sánchez-Martín; Miguel A Gallo; Antonio Espinosa
Conformational dynamics of a bispyridinium cyclophane.
The Journal of organic chemistry 2003;68(22):8697-9.
2003: Ana Conejo-García; Joaquín M Campos; Rosario M Sánchez-Martín; Miguel A Gallo; Antonio Espinosa
Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors.
Journal of medicinal chemistry 2003;46(17):3754-7.
2003: Joaquín Campos; María C Núñez; Ana Conejo-García; Rosario M Sánchez-Martín; Rubén Hernández-Alcoceba; Agustín Rodríguez-González; Juan Carlos Lacal; Miguel A Gallo; Antonio Espinosa
QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?
Current medicinal chemistry 2003;10(13):1095-112.
2003: Joaquín Campos; Carmen Núñez; Juan J Díaz; Rosario M Sánchez; Miguel A Gallo; Antonio Espinosa
Anticancer bisquaternary heterocyclic compounds: a ras-ional design.
Farmaco (Società chimica italiana : 1989) 2003;58(3):221-9.
2003: José F Domínguez; Juan A Marchal; Antonio Correa; Esmeralda Carrillo; Houria Boulaiz; Antonia Aránega; Miguel A Gallo; Antonio Espinosa
Synthesis and evaluation of new 5-fluorouracil antitumor cell differentiating derivatives.
Bioorganic & medicinal chemistry 2003;11(3):315-23.
2003: Ana Conejo-García; Joaquín Campos; Rosario M Sánchez; Agustín Rodríguez-González; Juan Carlos Lacal; Miguel A Gallo; Antonio Espinosa
Choline kinase inhibitory effect and antiproliferative activity of new 1,1',1"-(benzene-1,3,5-triylmethylene)tris[4-[(disubstituted)amino]pyridinium] tribromides.
European journal of medicinal chemistry 2003;38(1):109-16.
2002: Pier Giovanni Baraldi; LUISA-CARLOTA LÓPEZ-CARA; Antonio Entrena Guadix; Maria Josè Pineda de las Infantas; Miguel A Gallo; Antonio Espinosa; Alberto Martinez; John P Bingham; John A Hartley
Design, synthesis, and biological activity of hybrid compounds between uramustine and DNA minor groove binder distamycin A.
Journal of medicinal chemistry 2002;45(17):3630-8.
2002: Joaquín M Campos; María C Núñez; Rosario M Sánchez; José A Gómez-Vidal; Agustín Rodríguez-González; Mónica Báñez; Miguel A Gallo; Juan Carlos Lacal; Antonio Espinosa
Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds.
Bioorganic & medicinal chemistry 2002;10(7):2215-31.
2002: Albert Palomer; Francesc Cabré; Jaume Pascual; Joaquín Campos; María A Trujillo; Antonio Entrena; Miguel A Gallo; Lluïsa García; David Mauleón; Antonio Espinosa
Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models.
Journal of medicinal chemistry 2002;45(7):1402-11.
2002: Encarnación Camacho; Josefa León; Adoración Carrión; Antonio Entrena; Germaine Escames; Khaldy Belkadi Hoda; Darío Acuña-Castroviejo; Miguel A Gallo; Antonio Espinosa
Inhibition of nNOS activity in rat brain by synthetic kynurenines: structure-activity dependence.
Journal of medicinal chemistry 2002;45(2):263-74.
2001: Joaquín Campos; M del Carmen Núñez; V Rodríguez; Antonio Entrena; Rubén Hernández-Alcoceba; F Fernández; Juan Carlos Lacal; Miguel A Gallo; Antonio Espinosa
LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase.
European journal of medicinal chemistry 2001;36(3):215-25.
2000: Josefa León; Manuel Macías; Germaine Escames; Encarnación Camacho; Khaldy Belkadi Hoda; Miguel Martín; Antonio Espinosa; Miguel A Gallo; Darío Acuña-Castroviejo
Structure-related inhibition of calmodulin-dependent neuronal nitric-oxide synthase activity by melatonin and synthetic kynurenines.
Molecular pharmacology 2000;58(5):967-75.
2000: Juan A Marchal; Consolación Melguizo; José Prados; Antonia Aránega; JA Gómez; Joaquín Campos; Miguel A Gallo; Antonio Espinosa; Nicolò Arena; A Aránega
Modulation of myogenic differentiation in a human rhabdomyosarcoma cell line by a new derivative of 5-fluorouracil (QF-3602).
Japanese journal of cancer research : Gann 2000;91(9):934-40.
2000: Joaquín Campos; María C Núñez; V Rodríguez; Miguel A Gallo; Antonio Espinosa
QSAR of 1,1'-(1,2-ethylenebisbenzyl)bis(4-substitutedpyridinium) dibromides as choline kinase inhibitors: a different approach for antiproliferative drug design.
Bioorganic & medicinal chemistry letters 2000;10(8):767-70.
1999: Juan A Marchal; José Prados; Consolación Melguizo; JA Gómez; Joaquín Campos; Miguel A Gallo; Antonio Espinosa; Nicolò Arena; Antonia Aránega
GR-891: a novel 5-fluorouracil acyclonucleoside prodrug for differentiation therapy in rhabdomyosarcoma cells.
British journal of cancer 1999;79(5-6):807-13.
1998: Josefa León; Francisco Vives; E Crespo; Encarnación Camacho; Antonio Espinosa; Miguel A Gallo; Germaine Escames; Darío Acuña-Castroviejo
Modification of nitric oxide synthase activity and neuronal response in rat striatum by melatonin and kynurenine derivatives.
Journal of neuroendocrinology 1998;10(4):297-302.
1998: Josefa León; Francisco Vives; I Gómez; Encarnación Camacho; Miguel A Gallo; Antonio Espinosa; Germaine Escames; Darío Acuña-Castroviejo
Modulation of rat striatal glutamatergic response in search for new neuroprotective agents: evaluation of melatonin and some kynurenine derivatives.
Brain research bulletin 1998;45(5):525-30.
1997: Rubén Hernández-Alcoceba; L Saniger; Joaquín Campos; María C Núñez; F Khaless; Miguel A Gallo; Antonio Espinosa; Juan Carlos Lacal
Choline kinase inhibitors as a novel approach for antiproliferative drug design.
Oncogene 1997;15(19):2289-301.
1997: Joaquín Campos; JA Gómez; M A Trujillo; Miguel A Gallo; Antonio Espinosa; Juan A Marchal; Antonia Aránega
Diheterocyclanes as synthons for the preparation of novel series of nucleoside and acyclonucleoside analogues.
Farmaco (Società chimica italiana : 1989) 1997;52(5):263-9.
1995: M A Gallo-Mezo; Antonio Espinosa; Joaquín Campos; A Entrena; M J Pineda de las Infantas; J A Gómez
Anticancer pyrimidine acyclonucleosides.
Farmaco (Società chimica italiana : 1989) 1995;50(6):395-400.