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Joaquín Maximiliano Espinosa

Research Profile

Chemicals & Drugs

Physiology

Anatomy

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Protein Binding

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Chromatin Immunoprecipitation

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Publications

TOP 3
Corrie L Gallant-Behm; Joaquín Maximiliano Espinosa
How does ΔNp63α drive cancer?
Corrie L Gallant-Behm; Joaquín Maximiliano Espinosa
ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells.
Kelly D Sullivan; Aik Choon Tan; John J Tentler; James DeGregori; S Gail Eckhardt; Ryan E Henry; Jihye Kim; Nuria Padilla-Just; Christopher C Porter; Joaquín Maximiliano Espinosa
ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.

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All Publications

2013: Corrie L Gallant-Behm; Joaquín Maximiliano Espinosa
How does ΔNp63α drive cancer?
Epigenomics 2013;5(1):5-7.
2013: Corrie L Gallant-Behm; Joaquín Maximiliano Espinosa
ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells.
Cell cycle (Georgetown, Tex.) 2013;12(3):409-16.
2012: Kelly D Sullivan; Aik Choon Tan; John J Tentler; James DeGregori; S Gail Eckhardt; Ryan E Henry; Jihye Kim; Nuria Padilla-Just; Christopher C Porter; Joaquín Maximiliano Espinosa
ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.
Nature chemical biology 2012;8(7):646-54.
2012: Ryan E Henry; Ramiro París; Zdenek Andrysik; Matthew D Galbraith; Joaquín Maximiliano Espinosa
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX.
The EMBO journal 2012;31(5):1266-78.
2012: Joaquín Maximiliano Espinosa
Get back TFIIF, don't let me Gdown1.
Molecular cell 2012;45(1):3-5.
2011: Matthew D Galbraith; Joaquín Maximiliano Espinosa
Lessons on transcriptional control from the serum response network.
Current opinion in genetics & development 2011;21(2):160-6.
2010: Joaquín Maximiliano Espinosa
The meaning of pausing.
Molecular cell 2010;40(4):507-8.
2010: Nathan Gomes; Joaquín Maximiliano Espinosa
Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes.
Cell cycle (Georgetown, Tex.) 2010;9(17):3428-37.
2010: Matthew D Galbraith; Aaron J Donner; Joaquín Maximiliano Espinosa
CDK8: a positive regulator of transcription.
Transcription 2010;1(1):4-12.
2010: Nathan Gomes; Joaquín Maximiliano Espinosa
Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.
Genes & development 2010;24(10):1022-34.
2010: Aaron J Donner; Christopher C Ebmeier; Dylan J Taatjes; Joaquín Maximiliano Espinosa
CDK8 is a positive regulator of transcriptional elongation within the serum response network.
Nature structural & molecular biology 2010;17(2):194-201.
2010: Nathan Gomes; Joaquín Maximiliano Espinosa
Differential regulation of p53 target genes: it's (core promoter) elementary.
Genes & development 2010;24(2):111-4.
2008: Joaquín Maximiliano Espinosa
Histone H2B ubiquitination: the cancer connection.
Genes & development 2008;22(20):2743-9.
2008: Ramiro París; Ryan E Henry; Sarah J Stephens; Meagan McBryde; Joaquín Maximiliano Espinosa
Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation.
Cell cycle (Georgetown, Tex.) 2008;7(15):2427-33.
2008: Joaquín Maximiliano Espinosa
Mechanisms of regulatory diversity within the p53 transcriptional network.
Oncogene 2008;27(29):4013-23.
2008: Mark Wade; Luo-Wei Rodewald; Joaquín Maximiliano Espinosa; Geoffrey M Wahl
BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death.
Cell cycle (Georgetown, Tex.) 2008;7(13):1973-82.
2008: Krista D Meyer; Aaron J Donner; Matthew T Knuesel; Autumn G York; Joaquín Maximiliano Espinosa; Dylan J Taatjes
Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.
The EMBO journal 2008;27(10):1447-57.
2007: Aaron Joseph Donner; Jennifer Michelle Hoover; Stephanie Aspen Szostek; Joaquín Maximiliano Espinosa
Stimulus-specific transcriptional regulation within the p53 network.
Cell cycle (Georgetown, Tex.) 2007;6(21):2594-8.
2007: Aaron Joseph Donner; Stephanie Aspen Szostek; Jennifer Michelle Hoover; Joaquín Maximiliano Espinosa
CDK8 is a stimulus-specific positive coregulator of p53 target genes.
Molecular cell 2007;27(1):121-33.
2006: Nathan Gomes; Glen Bjerke; Briardo Llorente; Stephanie Aspen Szostek; Beverly M Emerson; Joaquín Maximiliano Espinosa
Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.
Genes & development 2006;20(5):601-12.
2003: Joaquín Maximiliano Espinosa; Ramiro Verdun; Beverly M Emerson
p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage.
Molecular cell 2003;12(4):1015-27.
2001: Joaquín Maximiliano Espinosa; Beverly M Emerson
Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.
Molecular cell 2001;8(1):57-69.