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Rafael Espinosa

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Alessandro Gozzetti; Elizabeth M Davis; Rafael Espinosa; Anthony A Fernald; John Anastasi; Michelle M Le Beau
Identification of novel cryptic translocations involving IGH in B-cell non-Hodgkin's lymphomas.
Shantel Corbin; Mary E Neilly; Rafael Espinosa; Elizabeth M Davis; Timothy W McKeithan; Michelle M Le Beau
Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors.
Mark K Abe; Matthew P Saelzler; Rafael Espinosa; Kristopher T Kahle; Marc B Hershenson; Michelle M Le Beau; Marsha Rich Rosner
ERK8, a new member of the mitogen-activated protein kinase family.

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2002: Alessandro Gozzetti; Elizabeth M Davis; Rafael Espinosa; Anthony A Fernald; John Anastasi; Michelle M Le Beau
Identification of novel cryptic translocations involving IGH in B-cell non-Hodgkin's lymphomas.
Cancer research 2002;62(19):5523-7.
2002: Shantel Corbin; Mary E Neilly; Rafael Espinosa; Elizabeth M Davis; Timothy W McKeithan; Michelle M Le Beau
Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors.
Cancer research 2002;62(12):3477-84.
2002: Mark K Abe; Matthew P Saelzler; Rafael Espinosa; Kristopher T Kahle; Marc B Hershenson; Michelle M Le Beau; Marsha Rich Rosner
ERK8, a new member of the mitogen-activated protein kinase family.
The Journal of biological chemistry 2002;277(19):16733-43.
2002: Theodore Karrison; Kellie J Archer; Rafael Espinosa; Ming Wen; Dezheng Huo
Data management and statistical methods used in the analysis of balanced chromosome abnormalities in therapy-related myelodysplastic syndromes and therapy-related acute leukemia: report from an international workshop.
Genes, chromosomes & cancer 2002;33(4):346-61.
2001: Y Sato; H Kobayashi; Y Suto; Harold J Olney; Elizabeth M Davis; H G Super; Rafael Espinosa; Michelle M Le Beau; Janet D Rowley
Chromosomal instability in chromosome band 12p13: multiple breaks leading to complex rearrangements including cytogenetically undetectable sub-clones.
Leukemia 2001;15(8):1193-202.
2001: Zhijian Qian; C Lin; Rafael Espinosa; Michelle M LeBeau; Marsha Rich Rosner
Cloning and characterization of MST4, a novel Ste20-like kinase.
The Journal of biological chemistry 2001;276(25):22439-45.
2001: F Lai; Lucy A Godley; J Joslin; Anthony A Fernald; J Liu; Rafael Espinosa; N Zhao; L Pamintuan; B G Till; Richard A Larson; Zhijian Qian; Michelle M Le Beau
Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).
Genomics 2001;71(2):235-45.
2000: PW Wang; JD Eisenbart; Rafael Espinosa; Elizabeth M Davis; Richard A Larson; Michelle M Le Beau
Refinement of the smallest commonly deleted segment of chromosome 20 in malignant myeloid diseases and development of a PAC-based physical and transcription map.
Genomics 2000;67(1):28-39.
2000: Judy H Cho; Dan L Nicolae; R Ramos; CT Fields; K Rabenau; S Corradino; Steven R Brant; Rafael Espinosa; Michelle M LeBeau; Stephen B Hanauer; J Bodzin; Denise K Bonen
Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease.
Human molecular genetics 2000;9(9):1425-32.
1998: N Zhao; F Lai; Anthony A Fernald; JD Eisenbart; Rafael Espinosa; PW Wang; Michelle M Le Beau
Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias.
Genomics 1998;53(2):184-90.
1998: Diane Roulston; Rafael Espinosa; Giuseppina Nucifora; Richard A Larson; Michelle M Le Beau; Janet D Rowley
CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: association with prior therapy.
Blood 1998;92(8):2879-85.
1998: Blanca Camoretti-Mercado; Sean M Forsythe; Michelle M LeBeau; Rafael Espinosa; Joaquim Vieira; Andrew J Halayko; S Willadsen; BS Kurtz; Carole Ober; G A Evans; R Thweatt; S Shapiro; Q Niu; Y Qin; PA Padrid; Julian Solway
Expression and cytogenetic localization of the human SM22 gene (TAGLN).
Genomics 1998;49(3):452-7.
1998: Michelle M Le Beau; Feyruz V Rassool; Mary E Neilly; Rafael Espinosa; Thomas W Glover; David I Smith; Timothy W McKeithan
Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction.
Human molecular genetics 1998;7(4):755-61.
1998: PW Wang; K Iannantuoni; Elizabeth M Davis; Rafael Espinosa; M Stoffel; Michelle M Le Beau
Refinement of the commonly deleted segment in myeloid leukemias with a del(20q).
Genes, chromosomes & cancer 1998;21(2):75-81.
1997: Y Sato; Stefan K Bohlander; H Kobayashi; SC Reshmi; Y Suto; Elizabeth M Davis; Rafael Espinosa; R Hoopes; Kate T Montgomery; Raju Kucherlapati; Michelle M Le Beau; Janet D Rowley
Heterogeneity in the breakpoints in balanced rearrangements involving band 12p13 in hematologic malignancies identified by fluorescence in situ hybridization: TEL (ETV6 ) is involved in only one half.
Blood 1997;90(12):4886-93.
1997: Y Sato; Stefan K Bohlander; H Kobayashi; Y Suto; Elizabeth M Davis; Rafael Espinosa; Michelle M Le Beau; Janet D Rowley
Identification of pericentric inversion 12, inv(12)(p13.1q11), by fluorescence in situ hybridization in a patient with acute myeloid leukemia (AML-M6).
Cancer genetics and cytogenetics 1997;97(2):157-60.
1997: N Zhao; Archontoula Stoffel; PW Wang; JD Eisenbart; Rafael Espinosa; Richard A Larson; Michelle M Le Beau
Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):6948-53.
1997: Riccardo Levi-Setti; JM Chabala; Konstantin L Gavrilov; Rafael Espinosa; Michelle M Le Beau
Imaging of BrdU-labeled human metaphase chromosomes with a high resolution scanning ion microprobe.
Microscopy research and technique 1997;36(4):301-12.
1996: S Tanabe; Stefan K Bohlander; C V Vignon; Rafael Espinosa; N Zhao; Pamela L Strissel; Nancy J Zeleznik-Le; Janet D Rowley
AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12).
Blood 1996;88(9):3535-45.
1996: Michelle M Le Beau; Rafael Espinosa; Elizabeth M Davis; JD Eisenbart; Richard A Larson; Eric Green
Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases.
Blood 1996;88(6):1930-5.
1996: Pamela L Strissel; Rafael Espinosa; Janet D Rowley; Hewson H Swift
Scaffold attachment regions in centromere-associated DNA.
Chromosoma 1996;105(2):122-33.
1996: Feyruz V Rassool; Michelle M Le Beau; M L Shen; M E Neilly; Rafael Espinosa; ST Ong; F Boldog; Harry A Drabkin; R McCarroll; Timothy W McKeithan
Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2.
Genomics 1996;35(1):109-17.
1996: Riccardo Levi-Setti; JM Chabala; Konstantin L Gavrilov; Rafael Espinosa; Michelle M Le Beau
Advances in high resolution SIMS studies of BrdU-labelled human metaphase chromosomes.
Cellular and molecular biology (Noisy-le-Grand, France) 1996;42(3):301-24.
1996: M Stoffel; Michelle M Le Beau; Rafael Espinosa; S F Bohlander; D Le Paslier; D Cohen; Kun-san Xiang; Nancy J Cox; SS Fajans; Graeme I Bell
A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):3937-41.
1996: S Tanabe; Nancy J Zeleznik-Le; H Kobayashi; C Vignon; Rafael Espinosa; M M LeBeau; M J Thirman; Janet D Rowley
Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line.
Genes, chromosomes & cancer 1996;15(4):206-16.
1995: J A Martinez-Climent; Rafael Espinosa; M J Thirman; Michelle M Le Beau; Janet D Rowley
Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival.
Journal of pediatric hematology/oncology 1995;17(4):277-83.
1995: J Takeda; Rafael Espinosa; S Eng; Michelle M Le Beau; Graeme I Bell
Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library.
Genomics 1995;29(1):276-81.
1995: J A Martinez-Climent; M J Thirman; Rafael Espinosa; Michelle M Le Beau; Janet D Rowley
Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.
Leukemia 1995;9(8):1299-304.
1995: Olufunmilayo I Olopade; H M Pomykala; F Hagos; L W Sveen; Rafael Espinosa; Martin Dreyling; S Gursky; Walter M Stadler; Michelle M Le Beau; Stefan K Bohlander
Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6489-93.
1995: M Stoffel; R Stein; C V Wright; Rafael Espinosa; Michelle M Le Beau; Graeme I Bell
Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1.
Genomics 1995;28(1):125-6.
1995: Meei-Ling Tsaur; Stephan Menzel; F P Lai; Rafael Espinosa; Patrick Concannon; Richard S Spielman; Craig L Hanis; Nancy J Cox; Michelle M Le Beau; Michael S German
Isolation of a cDNA clone encoding a KATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM.
Diabetes 1995;44(5):592-6.
1994: Rafael Espinosa; T Funahashi; C Hadjiagapiou; Michelle M Le Beau; Nicholas O Davidson
Assignment of the gene encoding the human apolipoprotein B mRNA editing enzyme (APOBEC1) to chromosome 12p13.1.
Genomics 1994;24(2):414-5.
1994: Michael S German; J Wang; A A Fernald; Rafael Espinosa; Michelle M Le Beau; G I Bell
Localization of the genes encoding two transcription factors, LMX1 and CDX3, regulating insulin gene expression to human chromosomes 1 and 13.
Genomics 1994;24(2):403-4.
1994: M Stoffel; Rafael Espinosa; J B Trabb; Michelle M Le Beau; Graeme I Bell
Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7.
Genomics 1994;23(3):697-9.
1994: E M Jones; Stephan Menzel; Rafael Espinosa; Michelle M Le Beau; Graeme I Bell; J Takeda
Localization of the gene encoding a neutral amino acid transporter-like protein to human chromosome band 19q13.3 and characterization of a simple sequence repeat DNA polymorphism.
Genomics 1994;23(2):490-1.
1994: M Stoffel; Rafael Espinosa; K L Powell; Louis H Philipson; Michelle M Le Beau; Graeme I Bell
Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism.
Genomics 1994;21(1):254-6.
1994: Stephan Menzel; M Stoffel; Rafael Espinosa; A A Fernald; Michelle M Le Beau; Graeme I Bell
Localization of the glucagon receptor gene to human chromosome band 17q25.
Genomics 1994;20(2):327-8.
1994: K Yasuda; Rafael Espinosa; J Takeda; Michelle M Le Beau; Graeme I Bell
Localization of the kappa opioid receptor gene to human chromosome band 8q11.2.
Genomics 1994;19(3):596-7.
1994: Stefan K Bohlander; Rafael Espinosa; A A Fernald; Janet D Rowley; Michelle M Le Beau; M O Díaz
Sequence-independent amplification and labeling of yeast artificial chromosomes for fluorescence in situ hybridization.
Cytogenetics and cell genetics 1994;65(1-2):108-10.
1994: Michelle M Le Beau; L A Carver; Rafael Espinosa; Jennifer Schmidt; Christopher A Bradfield
Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-->p15.
Cytogenetics and cell genetics 1994;66(3):172-6.
1994: Carol A Westbrook; Michelle M Le Beau; W L Neuman; M Keinanen; L H Yamaoka; M C Speer; Rafael Espinosa; Y Nakamura; R Williamson; M Mullan
Physical and genetic map of 5q31: use of fluorescence in situ hybridization data to identify errors in the CEPH database. Centre d'Etude de Polymorphisme Humain.
Cytogenetics and cell genetics 1994;67(2):86-93.
1993: M Lehto; Kun-san Xiang; M Stoffel; Rafael Espinosa; L C Groop; Michelle M Le Beau; Graeme I Bell
Human hexokinase II: localization of the polymorphic gene to chromosome 2.
Diabetologia 1993;36(12):1299-302.
1993: Diane Roulston; Rafael Espinosa; M Stoffel; Graeme I Bell; Michelle M Le Beau
Molecular genetics of myeloid leukemia: identification of the commonly deleted segment of chromosome 20.
Blood 1993;82(11):3424-9.
1993: H Kobayashi; Rafael Espinosa; A A Fernald; C Begy; Manuel O Diaz; Michelle M Le Beau; Janet D Rowley
Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization.
Genes, chromosomes & cancer 1993;8(4):246-52.
1993: K Yasuda; Rafael Espinosa; Elizabeth M Davis; Michelle M Le Beau; Graeme I Bell
Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2.
Genomics 1993;17(3):785-6.
1993: M Stoffel; Rafael Espinosa; Michelle M Le Beau; Graeme I Bell
Human glucagon-like peptide-1 receptor gene. Localization to chromosome band 6p21 by fluorescence in situ hybridization and linkage of a highly polymorphic simple tandem repeat DNA polymorphism to other markers on chromosome 6.
Diabetes 1993;42(8):1215-8.
1993: H Kobayashi; Rafael Espinosa; M J Thirman; A A Fernald; Kevin Shannon; Manuel O Diaz; Michelle M Le Beau; Janet D Rowley
Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization.
Genes, chromosomes & cancer 1993;7(4):204-8.
1993: H Kobayashi; Rafael Espinosa; M J Thirman; H J Gill; A A Fernald; Manuel O Diaz; Michelle M Le Beau; Janet D Rowley
Heterogeneity of breakpoints of 11q23 rearrangements in hematologic malignancies identified with fluorescence in situ hybridization.
Blood 1993;82(2):547-51.
1993: Michelle M Le Beau; Rafael Espinosa; W L Neuman; W Stock; Diane Roulston; Richard A Larson; M Keinanen; Carol A Westbrook
Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5484-8.
1993: Beverly W Baron; Giuseppina Nucifora; N McCabe; Rafael Espinosa; Michelle M Le Beau; Timothy W McKeithan
Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5262-6.
1993: H Kobayashi; Rafael Espinosa; M J Thirman; Elizabeth M Davis; Manuel O Diaz; Michelle M Le Beau; Janet D Rowley
Variability of 11q23 rearrangements in hematopoietic cell lines identified with fluorescence in situ hybridization.
Blood 1993;81(11):3027-33.
1993: Giuseppina Nucifora; D J Birn; Rafael Espinosa; Paul F Erickson; M M LeBeau; Diane Roulston; Timothy W McKeithan; Harry A Drabkin; Janet D Rowley
Involvement of the AML1 gene in the t(3;21) in therapy-related leukemia and in chronic myeloid leukemia in blast crisis.
Blood 1993;81(10):2728-34.
1993: R C Burnett; Rafael Espinosa; TB Shows; R L Eddy; M M LeBeau; Janet D Rowley; Manuel O Diaz
Molecular analysis of a t(11;14)(q23;q11) from a patient with null-cell acute lymphoblastic leukemia.
Genes, chromosomes & cancer 1993;7(1):38-46.
1993: M Stoffel; Rafael Espinosa; Susanna R Keller; G E Lienhard; Michelle M Le Beau; Graeme I Bell
Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism.
Diabetologia 1993;36(4):335-7.
1993: M Lehto; M Stoffel; L Groop; Rafael Espinosa; Michelle M Le Beau; Graeme I Bell
Assignment of the gene encoding glycogen synthase (GYS) to human chromosome 19, band q13.3.
Genomics 1993;15(2):460-1.
1993: Yoshihiko Yamada; M Stoffel; Rafael Espinosa; K S Xiang; M Seino; S Seino; Michelle M Le Beau; Graeme I Bell
Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms.
Genomics 1993;15(2):449-52.
1993: M Stoffel; Kun-san Xiang; Rafael Espinosa; Nancy J Cox; Michelle M Le Beau; Graeme I Bell
cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young.
Human molecular genetics 1993;2(1):1-4.
1993: W L Neuman; Carol A Westbrook; M Dixon; Rafael Espinosa; Y D Patel; Y Nakamura; B Weiffenbach; Michelle M Le Beau
Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization.
Cytogenetics and cell genetics 1993;62(4):207-10.
1992: D M White; D D Mikol; Rafael Espinosa; B Weimer; Michelle M Le Beau; Kari Stefansson
Structure and chromosomal localization of the human gene for a brain form of prostaglandin D2 synthase.
The Journal of biological chemistry 1992;267(32):23202-8.
1992: Michelle M Le Beau; C Ito; Patricia C Cogswell; Rafael Espinosa; A A Fernald; A S Baldwin
Chromosomal localization of the genes encoding the p50/p105 subunits of NF-kappa B (NFKB2) and the I kappa B/MAD-3 (NFKBI) inhibitor of NF-kappa B to 4q24 and 14q13, respectively.
Genomics 1992;14(2):529-31.
1992: Stefan K Bohlander; Rafael Espinosa; Michelle M Le Beau; Janet D Rowley; M O Díaz
A method for the rapid sequence-independent amplification of microdissected chromosomal material.
Genomics 1992;13(4):1322-4.
1992: S Seino; Yoshihiko Yamada; Rafael Espinosa; Michelle M Le Beau; Graeme I Bell
Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3.
Genomics 1992;13(4):1375-7.
1992: S Ohagi; J LaMendola; M M LeBeau; Rafael Espinosa; J Takeda; S P Smeekens; S J Chan; Donald F Steiner
Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):4977-81.
1992: Timothy W McKeithan; L Warshawsky; Rafael Espinosa; M M LeBeau
Molecular cloning of the breakpoints of a complex Philadelphia chromosome translocation: identification of a repeated region on chromosome 17.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):4923-7.
1992: Feyruz V Rassool; Michelle M Le Beau; M E Neilly; E van Melle; Rafael Espinosa; Timothy W McKeithan
Increased genetic instability of the common fragile site at 3p14 after integration of exogenous DNA.
American journal of human genetics 1992;50(6):1243-51.
1992: M Thangavelu; W L Neuman; Rafael Espinosa; Y Nakamura; Carol A Westbrook; Michelle M Le Beau
A physical and genetic linkage map of the distal long arm of human chromosome 5.
Cytogenetics and cell genetics 1992;59(1):27-30.
1991: S Ziemin-van der Poel; N R McCabe; H J Gill; Rafael Espinosa; Y Patel; A Harden; P Rubinelli; Stephen Dale Smith; M M LeBeau; Janet D Rowley
Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10735-9.
1991: Feyruz V Rassool; Timothy W McKeithan; M E Neilly; E van Melle; Rafael Espinosa; Michelle M Le Beau
Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6657-61.
1991: Rafael Espinosa; R S Lemons; R K Perlman; W L Kuo; Marsha Rich Rosner; Michelle M Le Beau
Localization of the gene encoding insulin-degrading enzyme to human chromosome 10, bands q23----q25.
Cytogenetics and cell genetics 1991;57(4):184-6.
1990: Janet D Rowley; Manuel O Diaz; Rafael Espinosa; Y D Patel; E van Melle; S Ziemin; P Taillon-Miller; P Lichter; G A Evans; J H Kersey
Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: identification of 11q23 translocation breakpoints with a yeast artificial chromosome.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9358-62.
1989: Rafael Espinosa; J E Sadler; Michelle M Le Beau
Regional localization of the human thrombomodulin gene to 20p12-cen.
Genomics 1989;5(3):649-50.
1989: Michelle M Le Beau; R S Lemons; Rafael Espinosa; Richard A Larson; N Arai; Janet D Rowley
Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).
Blood 1989;73(3):647-50.