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Ansgar Aasen

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Tom E Ruud; Ola Sveen; Yngvar Gundersen; Claus Danckert Krohn; Ansgar O Aasen
Effects of infliximab and hydrocortisone on in vitro cytokine responses after stimulation with lipopolysaccharide.
Claus V B Hviid; Signe F Kjeldsen; David Kunke; Yun Yong Wang; Shakil M Ahmed; Håvard Attramadal; Johanna Samulin Erdem; Ansgar O Aasen
The matri-cellular proteins 'cysteine-rich, angiogenic-inducer, 61' and 'connective tissue growth factor' are regulated in experimentally-induced sepsis with multiple organ dysfunction.
Yun Yong Wang; Ansgar O Aasen; Irshad H Chaudry; Jon L Collins; Maria K Dahle; Jan-Åke Gustafsson; Hilde I Nebb; Finn P Reinholt; Una Ryg; Knut R Steffensen; Christoph Thiemermann; Jacob E Wang
Liver X receptor protects against liver injury in sepsis caused by rodent cecal ligation and puncture.

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All Publications

2013: Tom E Ruud; Ola Sveen; Yngvar Gundersen; Claus Danckert Krohn; Ansgar O Aasen
Effects of infliximab and hydrocortisone on in vitro cytokine responses after stimulation with lipopolysaccharide.
Surgical infections 2013;14(1):30-4.
2012: Claus V B Hviid; Signe F Kjeldsen; David Kunke; Yun Yong Wang; Shakil M Ahmed; Håvard Attramadal; Johanna Samulin Erdem; Ansgar O Aasen
The matri-cellular proteins 'cysteine-rich, angiogenic-inducer, 61' and 'connective tissue growth factor' are regulated in experimentally-induced sepsis with multiple organ dysfunction.
Innate immunity 2012;18(5):717-26.
2011: Yun Yong Wang; Ansgar O Aasen; Irshad H Chaudry; Jon L Collins; Maria K Dahle; Jan-Åke Gustafsson; Hilde I Nebb; Finn P Reinholt; Una Ryg; Knut R Steffensen; Christoph Thiemermann; Jacob E Wang
Liver X receptor protects against liver injury in sepsis caused by rodent cecal ligation and puncture.
Surgical infections 2011;12(4):283-9.
2010: Yngvar Gundersen; Tom E Ruud; Claus Danckert Krohn; Ola Sveen; Ståle Petter Lyngstadaas; Ansgar O Aasen
Impact of hypertonic saline on the release of selected cytokines after stimulation with LPS or peptidoglycan in ex vivo whole blood from healthy humans.
Shock (Augusta, Ga.) 2010;34(5):450-4.
2009: Yun Yong Wang; Maria K Dahle; Knut R Steffensen; Finn P Reinholt; Jon L Collins; Christoph Thiemermann; Ansgar O Aasen; Jan-Ake Gustafsson; Jacob E Wang
Liver X receptor agonist GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages.
Shock (Augusta, Ga.) 2009;32(5):548-53.
2009: Olav Reikeras; Jingbo Sun; Jacob E Wang; Simon J Foster; Daniel Bastian; Ansgar O Aasen
Immunmodulation of serum in orthopaedic trauma.
The Journal of trauma 2009;67(3):624-7.
2008: Olav Reikerås; Jingbo Sun; Jacob E Wang; Simon J Foster; Ansgar O Aasen
Differences in LPS and PepG induced release of inflammatory cytokines in orthopedic trauma.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2008;21(5):255-60.
2008: Dietmar Tamandl; Pål Jørgensen; Yngvar Gundersen; Reinhold Fuegger; Thomas Sautner; Ansgar O Aasen; Peter Goetzinger
Nitric oxide administration restores the hepatic artery buffer response during porcine endotoxemia.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2008;21(4):183-94.
2008: R Yngvar Gundersen; Tom E Ruud; Pål Foyn Jørgensen; Tim Scholz; Finn P Reinholt; Jacob E Wang; Stale P Lyngstadaas; Ansgar O Aasen
Systemic administration of enamel matrix derivative to lipopolysaccharide-challenged pigs: effects on the inflammatory response.
Surgical infections 2008;9(2):161-9.
2008: Anders E Myhre; Joanna Agren; Maria K Dahle; Margareth V Tamburstuen; Ståle P Lyngstadaas; A Jon L Collins; Simon J Foster; Christoph Thiemermann; Ansgar O Aasen; Jacob E Wang
Liver X receptor is a key regulator of cytokine release in human monocytes.
Shock (Augusta, Ga.) 2008;29(4):468-74.
2007: Tom E Ruud; Yngvar Gundersen; Jacob E Wang; Simon J Foster; Christoph Thiemermann; Ansgar O Aasen
Activation of cytokine synthesis by systemic infusions of lipopolysaccharide and peptidoglycan in a porcine model in vivo and in vitro.
Surgical infections 2007;8(5):495-503.
2007: Olav Reikerås; Jingbo Sun; Jacob E Wang; Ansgar O Aasen
Postoperative serum attenuates LPS-induced release of TNF-alpha in orthopaedic surgery.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2007;25(10):1395-400.
2007: A Sandvik; Yun Yong Wang; Craig Morton; Ansgar O Aasen; Jacob E Wang; Finn-Eirik Johansen
Oral and systemic administration of beta-glucan protects against lipopolysaccharide-induced shock and organ injury in rats.
Clinical and experimental immunology 2007;148(1):168-77.
2007: Jacob E Wang; Ansgar O Aasen
Is inter-alpha inhibitor important in sepsis?
Critical care medicine 2007;35(2):634-5.
2007: Petter Kirkeby Risøe; Yunyong Wang; Jon Fredrik Stuestøl; Ansgar O Aasen; Jacob E Wang; Maria K Dahle
Lipopolysaccharide attenuates mRNA levels of several adenylyl cyclase isoforms in vivo.
Biochimica et biophysica acta 2007;1772(1):32-9.
2006: Jacob E Wang; Maria K Dahle; Ansgar O Aasen
Impaired monocyte Toll-like receptor-4 signaling in trauma and sepsis: is SIGIRR the answer?
Critical care medicine 2006;34(9):2498-500.
2006: Jeffrey L Johnson; Ernest E Moore; Ansgar O Aasen; Michael A Rogy; Jacob E Wang; Osamah Alsanea; Naoki Aikawa; Jorge A Neira; Gustavo J Tisminetzky
The role of the surgeon as intensivist: an international perspective.
Current opinion in critical care 2006;12(4):357-69.
2006: J Agren; Christoph Thiemermann; Simon J Foster; Jacob E Wang; Ansgar O Aasen
Cytokine responses to CpG DNA in human leukocytes.
Scandinavian journal of immunology 2006;64(1):61-8.
2006: Anders E Myhre; Staale Petter Lyngstadaas; Maria K Dahle; Jon Fredrik Stuestøl; Simon J Foster; Christoph Thiemermann; Per Lilleaasen; Jacob E Wang; Ansgar O Aasen
Anti-inflammatory properties of enamel matrix derivative in human blood.
Journal of periodontal research 2006;41(3):208-13.
2006: Anders E Myhre; Ansgar O Aasen; Christoph Thiemermann; Jacob E Wang
Peptidoglycan--an endotoxin in its own right?
Shock (Augusta, Ga.) 2006;25(3):227-35.
2006: Yun Yong Wang; Maria K Dahle; Joanna Agren; Anders E Myhre; Finn P Reinholt; Simon J Foster; Jon L Collins; Christoph Thiemermann; Ansgar O Aasen; Jacob E Wang
Activation of the liver X receptor protects against hepatic injury in endotoxemia by suppressing Kupffer cell activation.
Shock (Augusta, Ga.) 2006;25(2):141-6.
2006: Ansgar O Aasen; Jacob E Wang
Mediator responses in surgical infections.
Surgical infections 2006;7 Suppl 2():S3-4.
2005: Maria K Dahle; Anders E Myhre; Ansgar O Aasen; Jacob E Wang
Effects of forskolin on Kupffer cell production of interleukin-10 and tumor necrosis factor alpha differ from those of endogenous adenylyl cyclase activators: possible role for adenylyl cyclase 9.
Infection and immunity 2005;73(11):7290-6.
2005: Yun Yong Wang; Anders E Myhre; Solveig Pettersen; Maria K Dahle; Simon J Foster; Christoph Thiemermann; Kristin Bjørnland; Ansgar O Aasen; Jacob E Wang
Peptidoglycan of Staphylococcus aureus induces enhanced levels of matrix metalloproteinase-9 in human blood originating from neutrophils.
Shock (Augusta, Ga.) 2005;24(3):214-8.
2005: G Overland; Jon Fredrik Stuestøl; Maria K Dahle; Anders E Myhre; M G Netea; P Verweij; Arne Yndestad; Pål Aukrust; B J Kullberg; Adilia Warris; Jacob E Wang; Ansgar O Aasen
Cytokine responses to fungal pathogens in Kupffer Cells are Toll-like receptor 4 independent and mediated by tyrosine kinases.
Scandinavian journal of immunology 2005;62(2):148-54.
2005: O Reikeraas; J Sun; Claus Danckert Krohn; Jacob E Wang; Ansgar O Aasen
Reduced capacity of whole blood leucocytes to express tumour necrosis factor-alpha and interleukin-10 following major orthopaedic surgery.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2005;37(4):210-5.
2005: Jacob E Wang; Anders E Myhre; Ansgar O Aasen
Peptidoglycan: just another marker of postoperative infections or a mediator of disease?
Critical care medicine 2005;33(6):1441-2.
2004: Maria K Dahle; Gunhild Øverland; Anders E Myhre; Jon Fredrik Stuestøl; Thomas Hartung; Claus Danckert Krohn; Øystein Mathiesen; Jacob E Wang; Ansgar O Aasen
The phosphatidylinositol 3-kinase/protein kinase B signaling pathway is activated by lipoteichoic acid and plays a role in Kupffer cell production of interleukin-6 (IL-6) and IL-10.
Infection and immunity 2004;72(10):5704-11.
2004: Jacob E Wang; Solveig Pettersen; Jon Fredrik Stuestol; Yun Yong Wang; Simon J Foster; Christoph Thiemermann; Ansgar O Aasen; Kristin Bjørnland
Peptidoglycan of S. aureus causes increased levels of matrix metalloproteinases in the rat.
Shock (Augusta, Ga.) 2004;22(4):376-9.
2004: Anders E Myhre; Jon Fredrik Stuestøl; Maria K Dahle; Gunhild Øverland; Christoph Thiemermann; Simon J Foster; Per Lilleaasen; Ansgar O Aasen; Jacob E Wang
Organ injury and cytokine release caused by peptidoglycan are dependent on the structural integrity of the glycan chain.
Infection and immunity 2004;72(3):1311-7.
2004: Jacob E Wang; Maria K Dahle; Arne Yndestad; Inge Bauer; Michelle C McDonald; Pål Aukrust; Simon J Foster; Michael Bauer; Ansgar O Aasen; Christoph Thiemermann
Peptidoglycan of Staphylococcus aureus causes inflammation and organ injury in the rat.
Critical care medicine 2004;32(2):546-52.
2004: Ansgar O Aasen
The challenge of improving therapy of surgical intensive care patients.
Surgical infections 2004;5(1):3-7.
2003: Sanda Sturlan; Achim Schneeberger; Min Fang; Britta G Beinhauer; Petra Lührs; Raphaela Kutil; Barbara Wessner; Leaf Huang; Ansgar O Aasen; Michael A Rogy
Intraperitoneal administration of pMP6/liposome complexes inhibits the growth of co-localized colon-26 adenocarcinoma cells by inducing a tumor-specific immune response.
Anticancer research 2003;23(6C):4843-51.
2003: Jacob E Wang; Maria K Dahle; Michelle McDonald; Simon J Foster; Ansgar O Aasen; Christoph Thiemermann
Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism.
Shock (Augusta, Ga.) 2003;20(5):402-14.
2003: Kristin Bjørnland; Kjersti Flatmark; Tom Mala; Oystein Mathisen; Arne Bakka; Ansgar O Aasen; Anstein Bergan; Odd Søreide; Oystein Fodstad
Detection of disseminated tumour cells in bone marrow of patients with isolated liver metastases from colorectal cancer.
Journal of surgical oncology 2003;82(4):224-7.
2003: Sheraz Yaqub; Vigdis Solhaug; Torkel Vang; Rigmor Solberg; Ansgar O Aasen; Kjetil Taskén; Jacob E Wang
A human whole blood model of LPS-mediated suppression of T cell activation.
Medical science monitor : international medical journal of experimental and clinical research 2003;9(3):BR120-6.
2003: Gunhild Øverland; Sigfried Morath; Arne Yndestad; Thomas Hartung; Christoph Thiemermann; Simon J Foster; Bård Smedsrød; Øystein Mathisen; Pål Aukrust; Ansgar O Aasen; Jacob E Wang
Lipoteichoic acid is a potent inducer of cytokine production in rat and human Kupffer cells in vitro.
Surgical infections 2003;4(2):181-91.
2002: Sanda Sturlan; Britta G Beinhauer; Georg Oberhuber; Leaf Huang; Ansgar O Aasen; Michael A Rogy
In vivo gene transfer of murine interleukin-4 inhibits colon-26-mediated cancer cachexia in mice.
Anticancer research 2002;22(5):2547-54.
2002: Espen Ellingsen; Siegfried Morath; Trude H Flo; Andra Schromm; Thomas Hartung; Christoph Thiemermann; Terje Espevik; Douglas T Golenbock; Daniel Foster; Rigmor Solberg; Ansgar O Aasen; Jacob Wang
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(5):BR149-56.
2002: Ansgar O Aasen
Profile: Ansgar O. Aasen, M.D., Ph.D. Interview by Vicki Glaser.
Surgical infections 2002;3(1):49-52.
2002: Ansgar O Aasen; Philip Barie; Eugen Faist; Henri R Ford; Donald E Fry; Toni Hau
Panel discussion: current issues in the prevention and management of surgical site infection--part 2.
Surgical infections 2002;3 Suppl 1():S99-102.
2002: Ansgar O Aasen; Philip Barie; Eugen Faist; Henri R Ford; Donald E Fry; Toni Hau
Panel discussion: current issues in the prevention and management of surgical site infection--part 1.
Surgical infections 2002;3 Suppl 1():S1-7.
2002: Tim Scholz; Rigmor Solberg; Cecilie Okkenhaug; Vibeke Videm; Michael J Gallimore; Oystein Mathisen; Tom Eirik Mollnes; Anstein Bergan; Odd Søreide; Goran B Klintmalm; Ansgar O Aasen
The significance of heparin-coated veno-venous bypass circuits in liver transplantation.
Perfusion 2002;17(1):45-50.
2001: Pål Foyn Jørgensen; Peter Götzinger; Tim Scholz; Yngvar Gundersen; Thomas Sautner; Reinhold Függer; Per Lilleaasen; Ansgar O Aasen
The role of Kupffer cell inhibition in porcine endotoxemia.
Shock (Augusta, Ga.) 2001;16(6):466-72.
2001: Jacob E Wang; Pål Foyn Jørgensen; Espen Ellingsen; M Almiöf; Christoph Thiemermann; Simon J Foster; Ansgar O Aasen; Rigmor Solberg
Peptidoglycan primes for LPS-induced release of proinflammatory cytokines in whole human blood.
Shock (Augusta, Ga.) 2001;16(3):178-82.
2001: Tim Scholz; Rigmor Solberg; Cecilie Okkenhaug; Vibeke Videm; Michael J Gallimore; Oystein Mathisen; Thore Pedersen; Tom Eirik Mollnes; Anstein Bergan; Odd Søreide; Goran B Klintmalm; Ansgar O Aasen
Veno-venous bypass in liver transplantation: heparin-coated perfusion circuits reduce the activation of humoral defense systems in an in vitro model.
Perfusion 2001;16(4):285-92.
2001: Kristin Bjørnland; E Rugnes; Solveig Pettersen; HT Johansen; Ansgar O Aasen; Øystein Fodstad; Anne Hansen Ree; Gunhild M Maelandsmo
Expression of matrix metalloproteinases and the metastasis-associated gene S100A4 in human neuroblastoma and primitive neuroectodermal tumor cells.
Journal of pediatric surgery 2001;36(7):1040-4.
2001: Pål Foyn Jørgensen; Jacob E Wang; M Almlöf; Christoph Thiemermann; Simon J Foster; Rigmor Solberg; Ansgar O Aasen
Peptidoglycan and lipoteichoic acid modify monocyte phenotype in human whole blood.
Clinical and diagnostic laboratory immunology 2001;8(3):515-21.
2001: Jacob E Wang; Adilia Warris; Espen Ellingsen; Pål Foyn Jørgensen; Trude H Flo; Terje Espevik; Rigmor Solberg; P E Verweij; Ansgar O Aasen
Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae.
Infection and immunity 2001;69(4):2402-6.
2001: Pål Foyn Jørgensen; Jacob E Wang; Rigmor Solberg; Christoph Thiemermann; Simon J Foster; Ansgar O Aasen
Procalcitonin does not influence the surface expression of inflammatory receptors on whole blood leukocytes.
Intensive care medicine 2001;27(2):430-3.
2001: Pål Foyn Jørgensen; Jacob E Wang; M Almlöf; Rigmor Solberg; Cecilie Okkenhaug; Tim Scholz; Christoph Thiemermann; Simon J Foster; Ansgar O Aasen
Sirolimus interferes with the innate response to bacterial products in human whole blood by attenuation of IL-10 production.
Scandinavian journal of immunology 2001;53(2):184-91.
2001: T Saetre; Torstein Hovig; M Røger; Yngvar Gundersen; Ansgar O Aasen
Hepatocellular damage in porcine endotoxemia: beneficial effects of selective versus non-selective nitric oxide synthase inhibition?
Scandinavian journal of clinical and laboratory investigation 2001;61(7):503-12.
2000: Vibeke Videm; Jan L Svennevig; Erik Fosse; B Mohr; Ansgar O Aasen
Plasma endotoxin concentrations during cardiac surgery may be related to atherosclerosis.
Perfusion 2000;15(5):421-6.
2000: Jacob E Wang; Pål Foyn Jørgensen; M Almlöf; Christoph Thiemermann; Simon J Foster; Ansgar O Aasen; Rigmor Solberg
Peptidoglycan and lipoteichoic acid from Staphylococcus aureus induce tumor necrosis factor alpha, interleukin 6 (IL-6), and IL-10 production in both T cells and monocytes in a human whole blood model.
Infection and immunity 2000;68(7):3965-70.
2000: Jacob E Wang; Rigmor Solberg; Cecilie Okkenhaug; Pål Foyn Jørgensen; Claus Danckert Krohn; Ansgar O Aasen
Cytokine modulation in experimental endotoxemia: characterization of an ex vivo whole blood model.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2000;32(2):65-73.
1999: Yngvar Gundersen; T Saetre; Tim Scholz; Torstein Hovig; Per Lilleaasen; Ansgar O Aasen
Selective inhibition of inducible nitric oxide synthase maintains haemodynamic stability without untoward consequences for hepatic function or morphology.
The European journal of surgery = Acta chirurgica 1999;165(12):1167-74.
1999: Kristin Bjørnland; Jan-Olof Winberg; O T Odegaard; Eivind Hovig; Thrina Loennechen; Ansgar O Aasen; Oystein Fodstad; Gunhild M Maelandsmo
S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme.
Cancer research 1999;59(18):4702-8.
1999: Claus Danckert Krohn; Olav Reikerås; Ansgar O Aasen
Inflammatory cytokines and their receptors in arterial and mixed venous blood before, during and after infusion of drained untreated blood.
Transfusion medicine (Oxford, England) 1999;9(2):125-30.
1999: Vibeke Videm; Tom Eirik Mollnes; Kåre Bergh; Erik Fosse; B Mohr; Tor-Arne Hagve; Ansgar O Aasen; Jan L Svennevig
Heparin-coated cardiopulmonary bypass equipment. II. Mechanisms for reduced complement activation in vivo.
The Journal of thoracic and cardiovascular surgery 1999;117(4):803-9.
1999: Vibeke Videm; Tom Eirik Mollnes; Erik Fosse; B Mohr; Kåre Bergh; Tor-Arne Hagve; Ansgar O Aasen; Jan L Svennevig
Heparin-coated cardiopulmonary bypass equipment. I. Biocompatibility markers and development of complications in a high-risk population.
The Journal of thoracic and cardiovascular surgery 1999;117(4):794-802.
1999: Claus Danckert Krohn; Olav Reikerås; Ansgar O Aasen
The cytokines IL-1beta and IL-1 receptor antagonist, IL-2 and IL-2 soluble receptor-alpha, IL-6 and IL-6 soluble receptor, TNF-alpha and TNF soluble receptor I, and IL10 in drained and systemic blood after major orthopaedic surgery.
The European journal of surgery = Acta chirurgica 1999;165(2):101-9.
1999: Tim Scholz; Michael J Gallimore; L Bäckman; Oystein Mathisen; Anstein Bergan; Goran B Klintmalm; Ansgar O Aasen
Plasma proteolytic activity in liver transplant rejection.
Transplant international : official journal of the European Society for Organ Transplantation 1999;12(2):100-7.
1998: Yngvar Gundersen; Carlos Corso; Rosemarie Leiderer; Martina Dörger; Per Lilleaasen; Ansgar O Aasen; Konrad Messmer
The nitric oxide donor sodium nitroprusside protects against hepatic microcirculatory dysfunction in early endotoxaemia.
Intensive care medicine 1998;24(12):1257-63.
1998: T Saetre; Yngvar Gundersen; Otto A Smiseth; Tim Scholz; Harald Carlsen; L Nordsletten; Per Lilleaasen; Thomas Sautner; Reinhold Függer; Ansgar O Aasen
Hepatic oxygen metabolism in porcine endotoxemia: the effect of nitric oxide synthase inhibition.
The American journal of physiology 1998;275(6 Pt 1):G1377-85.
1998: Erik Trondsen; Arne R Rosseland; Arne Bakka; Tom E Ruud; T Martinsen; Ole Petter F Clausen; Anstein Bergan; Ansgar O Aasen
An experimental study on effects of monopolar diathermy on the bile ducts.
The European journal of surgery = Acta chirurgica 1998;164(4):297-303.
1998: Anne Hansen Ree; Kristin Bjørnland; N Brünner; HT Johansen; Kjetil Boye Pedersen; Ansgar O Aasen; Oystein Fodstad
Regulation of tissue-degrading factors and in vitro invasiveness in progression of breast cancer cells.
Clinical & experimental metastasis 1998;16(3):205-15.
1998: Kristin Bjørnland; L Buø; H Scott; Y Konttinen; HT Johansen; Ansgar O Aasen
Polymorphonuclear elastase in human colorectal carcinoma.
International journal of oncology 1998;12(3):535-40.
1998: Claus Danckert Krohn; Olav Reikerås; Tom Eirik Mollnes; Ansgar O Aasen
Complement activation and release of interleukin-6 and tumour necrosis factor-alpha in drained and systemic blood after major orthopaedic surgery.
The European journal of surgery = Acta chirurgica 1998;164(2):103-8.
1998: T Saetre; Yngvar Gundersen; Christoph Thiemermann; Per Lilleaasen; Ansgar O Aasen
Aminoethyl-isothiourea, a selective inhibitor of inducible nitric oxide synthase activity, improves liver circulation and oxygen metabolism in a porcine model of endotoxemia.
Shock (Augusta, Ga.) 1998;9(2):109-15.
1998: Kristin Bjørnland; Gustav Lehne; HT Johansen; Oystein Fodstad; Hans Erik Rugstad; Ansgar O Aasen; Anne Hansen Ree
Human hepatoma cells rich in P-glycoprotein display enhanced in vitro invasive properties compared to P-glycoprotein-poor hepatoma cells.
Oncology research 1998;10(5):255-62.
1998: Arnt E Fiane; Thore Pedersen; A Foerster; Tim Scholz; T H Perdersen; Hans E Karlsen; Jan L Svennevig; Odd Geiran; Ansgar O Aasen; Tom Eirik Mollnes
An ex vivo perfusion model to evaluate hyperacute rejection in a discordant pig-to-human combination.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1998;30(5):341-51.
1998: Rigmor Solberg; Tim Scholz; Vibeke Videm; Cecilie Okkenhaug; Ansgar O Aasen
Heparin coating reduces cell activation and mediator release in an in vitro venovenous bypass model for liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 1998;11(4):252-8.
1998: Carlos Corso; Yngvar Gundersen; Martina Dörger; Per Lilleaasen; Ansgar O Aasen; Konrad Messmer
Effects of the nitric oxide synthase inhibitors N(G)-nitro-L-arginine methyl ester and aminoethyl-isothiourea on the liver microcirculation in rat endotoxemia.
Journal of hepatology 1998;28(1):61-9.
1997: Yngvar Gundersen; Carlos Corso; Rosemarie Leiderer; Martina Dörger; Per Lilleaasen; Ansgar O Aasen; Konrad Messmer
Use of selective and nonselective nitric oxide synthase inhibitors in rat endotoxemia: effects on hepatic morphology and function.
Shock (Augusta, Ga.) 1997;8(5):368-72.
1997: Arnt E Fiane; Odd Geiran; O Søreide; Erik Thorsby; Ansgar O Aasen
[Transplantation of animal organs (xenotransplantation). Status and future development].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1997;117(8):1071-6.
1997: Yngvar Gundersen; T Saetre; Harald Carlsen; Tim Scholz; Per Lilleaasen; Ansgar O Aasen
Modulators of nitric oxide in porcine endotoxemia: effects on hepatic oxygen delivery and consumption.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1997;29(4):237-45.
1997: Tim Scholz; Oystein Mathisen; Anstein Bergan; S Osnes; R Innes; Thore Pedersen; Ansgar O Aasen; Odd Søreide
Percutaneous technique for venovenous bypass including a heat exchanger is safe and reliable in liver transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 1997;10(3):180-4.
1997: Erik Trondsen; Arne R Rosseland; Ole Petter F Clausen; Arne Bakka; E Engh; Einar Andreas Rødland; Ansgar O Aasen
An experimental study on effects of occlusion of the cystic duct in mice with or without emptying of the gallbladder.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1997;29(2):150-8.
1996: T Saetre; Otto A Smiseth; Tim Scholz; Harald Carlsen; L Nordsletten; E Fahlstrøm; Ansgar O Aasen
Nitric oxide synthase inhibition reduces venous return in porcine endotoxemia.
The American journal of physiology 1996;271(4 Pt 2):H1325-32.
1996: T S Karlsrud; L Buø; Ansgar O Aasen; HT Johansen
Cleavage of plasma high molecular weight kininogen in surgical ICU patients.
Intensive care medicine 1996;22(8):760-5.
1996: Lars Nordsletten; A K Høgåsen; Yrjö T Konttinen; Seppo Santavirta; Per Aspenberg; Ansgar O Aasen
Human monocytes stimulation by particles of hydroxyapatite, silicon carbide and diamond: in vitro studies of new prosthesis coatings.
Biomaterials 1996;17(15):1521-7.
1996: Kristin Bjørnland; L Buø; I Kjønniksen; M Larsen; Oystein Fodstad; HT Johansen; Ansgar O Aasen
Cysteine proteinase inhibitors reduce malignant melanoma cell invasion in vitro.
Anticancer research 1996;16(4A):1627-31.
1996: T S Karlsrud; L Buø; Ansgar O Aasen; HT Johansen
Bradykinin release from high molecular weight kininogen in surgical ICU patients.
Immunopharmacology 1996;33(1-3):365-8.
1996: T S Karlsrud; L Buø; Ansgar O Aasen; HT Johansen
Quantification of kininogens in plasma. A functional method based on the cysteine proteinase inhibitor activity.
Thrombosis research 1996;82(3):265-73.
1996: Lars Nordsletten; L Buo; M Takagi; Yrjö T Konttinen; M Yamakawa; Seppo Santavirta; Ansgar O Aasen
The plasminogen activation system is upregulated in loosening of total hip prostheses.
Acta orthopaedica Scandinavica 1996;67(2):143-8.
1996: Yngvar Gundersen; T Saetre; Tim Scholz; Harald Carlsen; Harald Kjekshus; Otto A Smiseth; Per Lilleaasen; Ansgar O Aasen
The NO donor sodium nitroprusside reverses the negative effects on hepatic arterial flow induced by endotoxin and the NO synthase inhibitor L-NAME.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1996;28(5):323-32.
1995: Arnt E Fiane; Vibeke Videm; Tim Scholz; Thore Pedersen; Hans E Karlsen; Odd Geiran; A Foerster; Tom Eirik Mollnes; Ansgar O Aasen; Jan L Svennevig
Ex vivo model for xenotransplantation.
Transplantation proceedings 1995;27(6):3560-1.
1995: L Buø; T S Karlsrud; G Dyrhaug; H Bell; L Engström; HT Johansen; Ansgar O Aasen
The fibrinolytic system in human ascites.
Scandinavian journal of gastroenterology 1995;30(11):1101-7.
1995: L Buø; G I Meling; T S Karlsrud; HT Johansen; Ansgar O Aasen
Antigen levels of urokinase plasminogen activator and its receptor at the tumor-host interface of colorectal adenocarcinomas are related to tumor aggressiveness.
Human pathology 1995;26(10):1133-8.
1995: A K Høgåsen; Lars Nordsletten; Ansgar O Aasen; J A Falch
There is no difference in spontaneous and 17 beta-estradiol-induced interleukin-1 beta release by peripheral blood mononuclear cells from nonosteoporotic women with different rates of early postmenopausal bone loss.
The Journal of clinical endocrinology and metabolism 1995;80(8):2480-4.
1995: Tim Scholz; L Backman; Oystein Mathisen; L Buø; T Karlsrud; HT Johansen; Anstein Bergan; G B Klintmalm; Ansgar O Aasen
Activation of the plasma contact system and hemodynamic changes after graft revascularization in liver transplantation.
Transplantation 1995;60(1):36-40.
1995: Kjell Saatvedt; Harald Lindberg; Odd Geiran; S Michelsen; Ansgar O Aasen; Thore Pedersen; Tom Eirik Mollnes
Complement activation and release of tumour necrosis factor alpha, interleukin-2, interleukin-6 and soluble tumour necrosis factor and interleukin-2 receptors during and after cardiopulmonary bypass in children.
Scandinavian journal of clinical and laboratory investigation 1995;55(1):79-86.
1994: HT Johansen; L Buøo; T S Karlsrud; Ansgar O Aasen
Dextran sulphate activation of the contact system in plasma and ascites.
Thrombosis research 1994;76(4):363-71.
1994: L Buø; Kristin Bjørnland; T S Karlsrud; D Kvale; I Kjønniksen; Oystein Fodstad; P Brandtzaeg; HT Johansen; Ansgar O Aasen
Expression and release of plasminogen activators, their inhibitors and receptor by human tumor cell lines.
Anticancer research 1994;14(6B):2445-51.
1994: O Sveen; K Borthne; Ansgar O Aasen
Computer acquisition, analysis and presentation of results from a Cobas Bio analyser.
Computers in biology and medicine 1994;24(6):493-504.
1994: F Naess; A Waage; O Roeise; J O Stadaas; Ansgar O Aasen
Effects of a combined drug regimen on tumour necrosis factor and plasma kallikrein activity in experimental endotoxaemia.
The European journal of surgery = Acta chirurgica 1994;160(2):77-86.
1994: Ragnhild Emblem; G Dhaenens; R Stien; Lars Mørkrid; Ansgar O Aasen; Anstein Bergan
The importance of anal endosonography in the evaluation of idiopathic fecal incontinence.
Diseases of the colon and rectum 1994;37(1):42-8.
1994: S Skjeldal; K Hvaal; Lars Nordsletten; Ansgar O Aasen; Olav Reikerås; A Torvik
Pentoxifylline reduces skeletal muscle necrosis after acute hindlimb ischemia in rats.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1994;26(2):94-100.
1993: L Buø; T S Karlsrud; G Dyrhaug; M B Jacobsen; H Bell; HT Johansen; Ansgar O Aasen
Differential diagnosis of human ascites: inhibitors of the contact system and total proteins.
Scandinavian journal of gastroenterology 1993;28(9):777-82.
1993: L Buø; T S Karlsrud; HT Johansen; Ansgar O Aasen
The contact system in human malignant and benign ascites.
Scandinavian journal of clinical and laboratory investigation 1993;53(2):117-24.
1993: L Buø; T Lyberg; L Jørgensen; HT Johansen; Ansgar O Aasen
Location of plasminogen activator (PA) and PA inhibitor in human colorectal adenocarcinomas.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1993;101(3):235-41.
1993: Ansgar O Aasen; J L Svennevig
[High-dose glucocorticoids in surgery and trauma].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1993;113(4):437-8.
1992: Ola Didrik Saugstad; L Buø; HT Johansen; O Røise; Ansgar O Aasen
Activation of the plasma kallikrein-kinin system in respiratory distress syndrome.
Pediatric research 1992;32(4):431-5.
1992: F Naess; O Roeise; HT Johansen; J O Stadaas; Ansgar O Aasen
Hemodynamic and proteolytic effects of intravenous injection of purified human plasma kallikrein.
The American journal of physiology 1992;263(2 Pt 2):H405-9.
1992: F Naess; O Roeise; J O Stadaas; Ansgar O Aasen
On the value of giving a combination of drugs for the treatment of endotoxaemia in pigs.
The European journal of surgery = Acta chirurgica 1992;158(2):95-103.
1992: U E Kongsgaard; Ansgar O Aasen; N Smith-Erichsen; L Bjørnskau
Effects of heparin on proteolytic activities in human plasma.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1992;24(2):119-28.
1992: L Buø; T S Karlsrud; HT Johansen; Ansgar O Aasen
Activation of the contact system in ascites from patients with gastrointestinal cancer.
Agents and actions. Supplements 1992;38 ( Pt 2)():237-48.
1991: T S Karlsrud; L Buø; Ansgar O Aasen; HT Johansen
Characterization of kininogens in human malignant ascites.
Thrombosis research 1991;63(6):641-50.
1991: T S Karlsrud; Ansgar O Aasen; HT Johansen
Evaluation of a microassay for human kininogens as cysteine protease inhibitors.
Journal of pharmacological methods 1991;26(2):113-24.
1991: F Naess; O Roeise; Johan Pillgram-Larsen; T E Ruud; J O Stadaas; Ansgar O Aasen
Plasma kallikrein generation in endotoxemia is abolished by ultra high doses of methyl-prednisolone: in vivo studies in a pig model.
Circulatory shock 1991;34(4):349-55.
1990: L Buø; Ansgar O Aasen; T S Karlsrud; HT Johansen; S M Sivertsen
[The role of proteases in the growth, invasion and spread of cancer cells].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 1990;110(29):3753-6.
1990: O Roeise; J H Nuijens; C E Hack; B N Bouma; J O Stadaas; Ansgar O Aasen
Methylprednisolone induces activation of the contact system in a dose-dependent manner. An in vitro study.
Thrombosis research 1990;57(6):877-88.
1990: O Roeise; S Sivertsen; T E Ruud; B N Bouma; J O Stadaas; Ansgar O Aasen
Studies on components of the contact phase system in patients with advanced gastrointestinal cancer.
Cancer 1990;65(6):1355-9.
1990: F Naess; O Roeise; J O Stadaas; Ansgar O Aasen
Combined drug therapy in porcine endotoxemia. Hemodynamic and proteolytic effects of antagonists against histamine, serotonin and endorphin.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1990;22(3):160-9.
1990: O Roeise; Peter Garred; Tom Eirik Mollnes; J O Stadaas; Ansgar O Aasen
Methylprednisolone in high doses gives different effects on the early and the late part of complement.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1990;22(1):41-9.
1989: O Roeise; J O Stadaas; Ansgar O Aasen
Methylprednisolone affects inhibitors of the complement and the contact systems; functional and immunochemical studies on alpha 2-macroglobulin and C1 inhibitor.
Thrombosis research 1989;56(6):697-708.
1989: F Naess; O Roeise; J Pillgram-Larsen; T E Ruud; J O Stadaas; Ansgar O Aasen
Plasma proteolysis and circulating cells in relation to varying endotoxin concentrations in porcine endotoxemia.
Circulatory shock 1989;28(2):89-100.
1989: O Roeise; Peter Garred; Tom Eirik Mollnes; Ansgar O Aasen
Studies on the dose dependence of endotoxin-induced in vitro activation of the complement system.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1989;21(1):34-41.
1989: O Røise; B N Bouma; J O Stadaas; Ansgar O Aasen
Studies on interactions of endotoxin with factors of the contact system of plasma.
Progress in clinical and biological research 1989;308():401-5.
1989: F Naess; O Røise; J Pillgram-Larsen; T E Ruud; J O Stadaas; Ansgar O Aasen
Hemodynamic and proteolytic responses in relation to plasma endotoxin concentrations in porcine endotoxemia.
Progress in clinical and biological research 1989;308():389-93.
1989: Ansgar O Aasen; A L Rishovd; J O Stadaas
Role of endotoxin and proteases in multiple organ failure (MOF).
Progress in clinical and biological research 1989;308():315-22.
1989: O Røise; F Naess; J Pillgram-Larsen; T E Ruud; J O Stadaas; Ansgar O Aasen
Influence of methylprednisolone pretreatment on coagulation, fibrinolysis, hemodynamics and cellular responses in porcine endotoxemia.
Progress in clinical and biological research 1989;308():873-7.
1989: Ansgar O Aasen; T E Ruud; O Roeise; B N Bouma; J O Stadaas
Peritoneal lavage efficiently eliminates protease-alpha-2-macroglobulin complexes and components of the contact system from the peritoneal cavity in patients with severe acute pancreatitis.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1989;21(1):1-10.
1988: O Roeise; B N Bouma; J O Stadaas; Ansgar O Aasen
Dose dependence of endotoxin-induced activation of the plasma contact system: an in vitro study.
Circulatory shock 1988;26(4):419-30.
1987: B Lium; T E Ruud; J Pillgram-Larsen; J O Stadaas; Ansgar O Aasen
Sodium taurocholate-induced acute pancreatitis in pigs. Pathomorphological studies of the pancreas in untreated animals and animals pretreated with high doses of corticosteroids or protease inhibitors.
Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology 1987;95(6):377-82.
1987: F Naess; J Pillgram-Larsen; T E Ruud; J O Stadaas; Ansgar O Aasen
Hemodynamics and proteolysis in experimental trypsin induced shock.
Progress in clinical and biological research 1987;236A():185-92.
1986: Ansgar O Aasen; N Smith-Erichsen; E Amundsen
Uncontrolled plasma proteolysis: a major threat to the septicemic patient.
Resuscitation 1986;14(1-2):33-42.
1986: T E Ruud; Ansgar O Aasen; O Røise; B Lium; J Pillgram-Larsen; J O Stadaas
Effects on peritoneal proteolysis and hemodynamics by high doses of methyl-prednisolone in experimental acute pancreatitis.
Scandinavian journal of gastroenterology. Supplement 1986;126():25-31.
1985: Ansgar O Aasen; N Smith-Erichsen; E Amundsen
Studies on pathological plasma proteolysis in patients with septicemia.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1985;178():37-45.
1984: N Smith-Erichsen; Ansgar O Aasen; E Amundsen
Changes in components of the plasma protease systems related to course and outcome of surgical sepsis.
Advances in experimental medicine and biology 1984;167():455-62.
1983: Ansgar O Aasen; N Smith-Erichsen; E Amundsen
Plasma kallikrein-kinin system in septicemia.
Archives of surgery (Chicago, Ill. : 1960) 1983;118(3):343-6.
1983: N Smith-Erichsen; Ansgar O Aasen; E Amundsen
The functional inhibition of plasma kallikrein. A critical factor in septic shock.
Advances in experimental medicine and biology 1983;156 (Pt B)():1049-54.
1982: B Lium; Ansgar O Aasen; O D Saugstad; I Guldvog; K Nordstoga; E Amundsen
Experimental post-traumatic lung insufficiency in dogs: ultrastructure of lung lesions.
Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology 1982;90(2):113-23.
1982: N Smith-Erichsen; Ansgar O Aasen; M J Gallimore; E Amundsen
Studies of components of the coagulation systems in normal individuals and septic shock patients.
Circulatory shock 1982;9(5):491-7.
1982: O D Saugstad; Ansgar O Aasen; I Guldvog; B Lium; K Lyngaas; E Amundsen
Changes of components of the plasma kallikrein-kinin system during experimental lung insufficiency in dogs.
Acta chirurgica Scandinavica. Supplementum 1982;509():61-7.
1982: N Smith-Erichsen; Ansgar O Aasen; E Amundsen
Treatment of sepsis in the surgical patient evaluated by means of chromogenic peptide substrate assays.
Acta chirurgica Scandinavica. Supplementum 1982;509():33-8.
1980: M J Gallimore; Ansgar O Aasen; N S Erichsen; M Larsbraaten; K Lyngaas; E Amundsen
Plasminogen concentrations and functional activities and concentrations of plasmin inhibitors in plasma samples from normal subjects and patients with septic shock.
Thrombosis research 1980;18(5):601-8.
1980: I Guldvog; O D Saugstad; Ansgar O Aasen; J Dale; B Lium; M Larsbraaten; K Lyngaas; E Amundsen
Blood cells and coagulation during experimental lung insufficiency in dogs.
Acta chirurgica Scandinavica. Supplementum 1980;499():131-9.
1980: O D Saugstad; Ansgar O Aasen; I Guldvog; B Lium; M Larsbraaten; K Lyngaas; E Amundsen
Activation of the kallikrein-kinin system during experimental lung insufficiency in dogs.
Acta chirurgica Scandinavica. Supplementum 1980;499():123-9.
1980: Ansgar O Aasen; O D Saugstad; B Lium; I Guldvog; K Lyngaas; M Larsbraaten; E Amundsen
Plasma antiplasmin activities in experimental lung insufficiency.
Acta chirurgica Scandinavica. Supplementum 1980;499():113-21.
1980: Ansgar O Aasen; N S Erichsen; M J Gallimore; E Amundsen
Studies on components of the plasma kallikrein-kinin system in plasma samples from normal individuals and patients with septic shock.
Advances in shock research 1980;4():1-10.