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Ronald Evans

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

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Lamia Katja A; Sachdeva Uma M; DiTacchio Luciano; Williams Elliot C; Alvarez Jacqueline G; Egan Daniel F; Vasquez Debbie S; Juguilon Henry; Panda Satchidananda; Shaw Reuben J; Thompson Craig B; Evans Ronald M
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.
Pei Liming; Evans Ronald M
Retrofitting fat metabolism.
McKenna Neil J; Cooney Austin J; DeMayo Francesco J; Downes Michael; Glass Christopher K; Lanz Rainer B; Lazar Mitchell A; Mangelsdorf David J; Moore David D; Qin Jun; Steffen David L; Tsai Ming-Jer; Tsai Sophia Y; Yu Ruth; Margolis Ronald N; Evans Ronald M; O'Malley Bert W
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.

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All Publications

2009: Lamia Katja A; Sachdeva Uma M; DiTacchio Luciano; Williams Elliot C; Alvarez Jacqueline G; Egan Daniel F; Vasquez Debbie S; Juguilon Henry; Panda Satchidananda; Shaw Reuben J; Thompson Craig B; Evans Ronald M
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.
Science (New York, N.Y.) 2009;326(5951):437-40.
2009: Pei Liming; Evans Ronald M
Retrofitting fat metabolism.
Cell metabolism 2009;9(6):483-4.
2009: McKenna Neil J; Cooney Austin J; DeMayo Francesco J; Downes Michael; Glass Christopher K; Lanz Rainer B; Lazar Mitchell A; Mangelsdorf David J; Moore David D; Qin Jun; Steffen David L; Tsai Ming-Jer; Tsai Sophia Y; Yu Ruth; Margolis Ronald N; Evans Ronald M; O'Malley Bert W
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.
Molecular endocrinology (Baltimore, Md.) 2009;23(6):740-6.
2008: Nofsinger Russell R; Li Pingping; Hong Suk-Hyun; Jonker Johan W; Barish Grant D; Ying Hao; Cheng Sheue-Yann; Leblanc Mathias; Xu Wei; Pei Liming; Kang Yeon-Joo; Nelson Michael; Downes Michael; Yu Ruth T; Olefsky Jerrold M; Lee Chih-Hao; Evans Ronald M
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(50):20021-6.
2008: Davies Brandon S J; Waki Hironori; Beigneux Anne P; Farber Emily; Weinstein Michael M; Wilpitz Damien C; Tai Li-Jung; Evans Ronald M; Fong Loren G; Tontonoz Peter; Young Stephen G
The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma.
Molecular endocrinology (Baltimore, Md.) 2008;22(11):2496-504.
2008: Yang Chul-Su; Ko Sung-Ryong; Cho Byung-Goo; Shin Dong-Min; Yuk Jae-Min; Li Shengjin; Kim Jin-Man; Evans Ronald M; Jung Jun-Sub; Song Dong-Keun; Jo Eun-Kyeong
The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock.
Journal of cellular and molecular medicine 2008;12(5A):1739-53.
2008: Narkar Vihang A; Downes Michael; Yu Ruth T; Embler Emi; Wang Yong-Xu; Banayo Ester; Mihaylova Maria M; Nelson Michael C; Zou Yuhua; Juguilon Henry; Kang Heonjoong; Shaw Reuben J; Evans Ronald M
AMPK and PPARdelta agonists are exercise mimetics.
Cell 2008;134(3):405-15.
2008: Barish Grant D; Atkins Annette R; Downes Michael; Olson Peter; Chong Ling-Wa; Nelson Mike; Zou Yuhua; Hwang Hoosang; Kang Heonjoong; Curtiss Linda; Evans Ronald M; Lee Chih-Hao
PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4271-6.
2008: Takata Yasunori; Liu Joey; Yin Fen; Collins Alan R; Lyon Christopher J; Lee Chih-Hao; Atkins Annette R; Downes Michael; Barish Grant D; Evans Ronald M; Hsueh Willa A; Tangirala Rajendra K
PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4277-82.
2008: Downes Michael; Evans Ronald M
Staying the distance: avoiding the proteasomal trap.
Cancer cell 2008;13(3):184-5.
2008: Yang Xiaoyong; Ongusaha Pat P; Miles Philip D; Havstad Joyce C; Zhang Fengxue; So W Venus; Kudlow Jeffrey E; Michell Robert H; Olefsky Jerrold M; Field Seth J; Evans Ronald M
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance.
Nature 2008;451(7181):964-9.
2008: Zhang Chun-Li; Zou Yuhua; He Weimin; Gage Fred H; Evans Ronald M
A role for adult TLX-positive neural stem cells in learning and behaviour.
Nature 2008;451(7181):1004-7.
2008: Man Mao-Qiang; Barish Grant D; Schmuth Matthias; Crumrine Debra; Barak Yaacov; Chang Sandra; Jiang Yan; Evans Ronald M; Elias Peter M; Feingold Kenneth R
Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation.
The Journal of investigative dermatology 2008;128(2):370-7.
2008: Sonoda Junichiro; Pei Liming; Evans Ronald M
Nuclear receptors: decoding metabolic disease.
FEBS letters 2008;582(1):2-9.
2007: Wan Yihong; Chong Ling-Wa; Evans Ronald M
PPAR-gamma regulates osteoclastogenesis in mice.
Nature medicine 2007;13(12):1496-503.
2007: Ding Guoliang; Fu Mingui; Qin Qianhong; Lewis William; Kim Ha Won; Fukai Tohru; Bacanamwo Methode; Chen Yuqing Eugene; Schneider Michael D; Mangelsdorf David J; Evans Ronald M; Yang Qinglin
Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting cardiomyocytes from oxidative damage.
Cardiovascular research 2007;76(2):269-79.
2007: Sun Guoqiang; Yu Ruth T; Evans Ronald M; Shi Yanhong
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(39):15282-7.
2007: Sonoda Junichiro; Laganière Josée; Mehl Isaac R; Barish Grant D; Chong Ling-Wa; Li Xiangli; Scheffler Immo E; Mock Dennis C; Bataille Alain R; Robert Francois; Lee Chih-Hao; Giguère Vincent; Evans Ronald M
Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense.
Genes & development 2007;21(15):1909-20.
2007: Wan Yihong; Saghatelian Alan; Chong Ling-Wa; Zhang Chun-Li; Cravatt Benjamin F; Evans Ronald M
Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk.
Genes & development 2007;21(15):1895-908.
2007: Alaynick William A; Kondo Richard P; Xie Wen; He Weimin; Dufour Catherine R; Downes Michael; Jonker Johan W; Giles Wayne; Naviaux Robert K; Giguère Vincent; Evans Ronald M
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.
Cell metabolism 2007;6(1):13-24.
2007: Dufour Catherine R; Wilson Brian J; Huss Janice M; Kelly Daniel P; Alaynick William A; Downes Michael; Evans Ronald M; Blanchette Mathieu; Giguère Vincent
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.
Cell metabolism 2007;5(5):345-56.
2007: Sonoda Junichiro; Mehl Isaac R; Chong Ling-Wa; Nofsinger Russell R; Evans Ronald M
PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5223-8.
2007: Yoh Sunnie M; Cho Helen; Pickle Loni; Evans Ronald M; Jones Katherine A
The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export.
Genes & development 2007;21(2):160-74.
2007: Yang X; Lamia K A; Evans R M
Nuclear receptors, metabolism, and the circadian clock.
Cold Spring Harbor symposia on quantitative biology 2007;72():387-94.
2006: Germain Pierre; Chambon Pierre; Eichele Gregor; Evans Ronald M; Lazar Mitchell A; Leid Mark; De Lera Angel R; Lotan Reuben; Mangelsdorf David J; Gronemeyer Hinrich
International Union of Pharmacology. LXIII. Retinoid X receptors.
Pharmacological reviews 2006;58(4):760-72.
2006: Germain Pierre; Chambon Pierre; Eichele Gregor; Evans Ronald M; Lazar Mitchell A; Leid Mark; De Lera Angel R; Lotan Reuben; Mangelsdorf David J; Gronemeyer Hinrich
International Union of Pharmacology. LX. Retinoic acid receptors.
Pharmacological reviews 2006;58(4):712-25.
2006: Yang Xiaoyong; Downes Michael; Yu Ruth T; Bookout Angie L; He Weimin; Straume Marty; Mangelsdorf David J; Evans Ronald M
Nuclear receptor expression links the circadian clock to metabolism.
Cell 2006;126(4):801-10.
2006: Bookout Angie L; Jeong Yangsik; Downes Michael; Yu Ruth T; Evans Ronald M; Mangelsdorf David J
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network.
Cell 2006;126(4):789-99.
2006: Stedman Catherine; Liddle Christopher; Coulter Sally; Sonoda Junichiro; Alvarez Jacqueline G; Evans Ronald M; Downes Michael
Benefit of farnesoid X receptor inhibition in obstructive cholestasis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(30):11323-8.
2006: Qi Ling; Heredia Jose E; Altarejos Judith Y; Screaton Robert; Goebel Naomi; Niessen Sherry; Macleod Ian X; Liew Chong Wee; Kulkarni Rohit N; Bain James; Newgard Christopher; Nelson Michael; Evans Ronald M; Yates John; Montminy Marc
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.
Science (New York, N.Y.) 2006;312(5781):1763-6.
2006: Zhang Chun-Li; Zou Yuhua; Yu Ruth T; Gage Fred H; Evans Ronald M
Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1.
Genes & development 2006;20(10):1308-20.
2006: Zhou Jie; Zhai Yonggong; Mu Ying; Gong Haibiao; Uppal Hirdesh; Toma David; Ren Songrong; Evans Ronald M; Xie Wen
A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.
The Journal of biological chemistry 2006;281(21):15013-20.
2006: Barish Grant D; Narkar Vihang A; Evans Ronald M
PPAR delta: a dagger in the heart of the metabolic syndrome.
The Journal of clinical investigation 2006;116(3):590-7.
2006: Jacobs Sharoni; Lie D Chichung; DeCicco Kathleen L; Shi Yanhong; DeLuca Luigi M; Gage Fred H; Evans Ronald M
Retinoic acid is required early during adult neurogenesis in the dentate gyrus.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3902-7.
2006: Lee Chih-Hao; Olson Peter; Hevener Andrea; Mehl Isaac; Chong Ling-Wa; Olefsky Jerrold M; Gonzalez Frank J; Ham Jungyeob; Kang Heonjoong; Peters Jeffrey M; Evans Ronald M
PPARdelta regulates glucose metabolism and insulin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3444-9.
2006: Sternsdorf Thomas; Phan Vernon T; Maunakea Mei Lin; Ocampo Corinne B; Sohal Jastinder; Silletto Angela; Galimi Francesco; Le Beau Michelle M; Evans Ronald M; Kogan Scott C
Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia.
Cancer cell 2006;9(2):81-94.
2006: Lee Chih-Hao; Kang Kihwa; Mehl Isaac R; Nofsinger Russell; Alaynick William A; Chong Ling-Wa; Rosenfeld John M; Evans Ronald M
Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2434-9.
2006: Wang Zhiyong; Qi Chao; Krones Anna; Woodring Pamela; Zhu Xiaoyan; Reddy Janardan K; Evans Ronald M; Rosenfeld Michael G; Hunter Tony
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance.
Cell metabolism 2006;3(2):111-22.
2005: Zhao Xuan; Sternsdorf Thomas; Bolger Timothy A; Evans Ronald M; Yao Tso-Pang
Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications.
Molecular and cellular biology 2005;25(19):8456-64.
2005: Margolis Ronald N; Evans Ronald M; O'Malley Bert W;
The Nuclear Receptor Signaling Atlas: development of a functional atlas of nuclear receptors.
Molecular endocrinology (Baltimore, Md.) 2005;19(10):2433-6.
2005: Barish Grant D; Downes Michael; Alaynick William A; Yu Ruth T; Ocampo Corinne B; Bookout Angie L; Mangelsdorf David J; Evans Ronald M
A Nuclear Receptor Atlas: macrophage activation.
Molecular endocrinology (Baltimore, Md.) 2005;19(10):2466-77.
2005: Fu Mingui; Sun Tingwan; Bookout Angie L; Downes Michael; Yu Ruth T; Evans Ronald M; Mangelsdorf David J
A Nuclear Receptor Atlas: 3T3-L1 adipogenesis.
Molecular endocrinology (Baltimore, Md.) 2005;19(10):2437-50.
2005: Evans Ronald M
The nuclear receptor superfamily: a rosetta stone for physiology.
Molecular endocrinology (Baltimore, Md.) 2005;19(6):1429-38.
2005: Stedman Catherine A M; Liddle Christopher; Coulter Sally A; Sonoda Junichiro; Alvarez Jacqueline G A; Moore David D; Evans Ronald M; Downes Michael
Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2063-8.
2005: Sonoda Junichiro; Chong Ling Wa; Downes Michael; Barish Grant D; Coulter Sally; Liddle Christopher; Lee Chih-Hao; Evans Ronald M
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2198-203.
2005: Galimi Francesco; Saez Enrique; Gall Jason; Hoong Nien; Cho Gerald; Evans Ronald M; Verma Inder M
Development of ecdysone-regulated lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;11(1):142-8.
2004: Shalom-Barak Tali; Nicholas Jill M; Wang Yongxu; Zhang Xiaowen; Ong Estelita S; Young Timothy H; Gendler Sandra J; Evans Ronald M; Barak Yaacov
Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts.
Molecular and cellular biology 2004;24(24):10661-9.
2004: Cheng Lihong; Ding Guoliang; Qin Qianhong; Huang Yao; Lewis William; He Nu; Evans Ronald M; Schneider Michael D; Brako Florence A; Xiao Yan; Chen Yuqing E; Yang Qinglin
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy.
Nature medicine 2004;10(11):1245-50.
2004: Zhang Jun; Huang Wendong; Qatanani Mohammed; Evans Ronald M; Moore David D
The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
The Journal of biological chemistry 2004;279(47):49517-22.
2004: Barish Grant D; Evans Ronald M
A nuclear strike against Listeria--the evolving life of LXR.
Cell 2004;119(2):149-51.
2004: Wang Yong-Xu; Zhang Chun-Li; Yu Ruth T; Cho Helen K; Nelson Michael C; Bayuga-Ocampo Corinne R; Ham Jungyeob; Kang Heonjoong; Evans Ronald M
Regulation of muscle fiber type and running endurance by PPARdelta.
PLoS biology 2004;2(10):e294.
2004: Evans Ronald M
2003 Keio Medical Science Prize commemorative lecture. PPARs and the complex journey to obesity.
The Keio journal of medicine 2004;53(2):53-8.
2004: Barish Grant D; Evans Ronald M
PPARs and LXRs: atherosclerosis goes nuclear.
Trends in endocrinology and metabolism: TEM 2004;15(4):158-65.
2004: Koo Seung-Hoi; Satoh Hiroaki; Herzig Stephan; Lee Chih-Hao; Hedrick Susan; Kulkarni Rohit; Evans Ronald M; Olefsky Jerrold; Montminy Marc
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.
Nature medicine 2004;10(5):530-4.
2004: Assem Mahfoud; Schuetz Erin G; Leggas Markos; Sun Daxi; Yasuda Kazuto; Reid Glen; Zelcer Noam; Adachi Masashi; Strom Stephen; Evans Ronald M; Moore David D; Borst Piet; Schuetz John D
Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice.
The Journal of biological chemistry 2004;279(21):22250-7.
2004: Evans Ronald M; Barish Grant D; Wang Yong-Xu
PPARs and the complex journey to obesity.
Nature medicine 2004;10(4):355-61.
2004: Saez Enrique; Rosenfeld John; Livolsi Antonia; Olson Peter; Lombardo Eleuterio; Nelson Michael; Banayo Ester; Cardiff Robert D; Izpisua-Belmonte Juan Carlos; Evans Ronald M
PPAR gamma signaling exacerbates mammary gland tumor development.
Genes & development 2004;18(5):528-40.
2004: Tsai Chih-Cheng; Kao Hung-Ying; Mitzutani Akifumi; Banayo Ester; Rajan Harini; McKeown Michael; Evans Ronald M
Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4047-52.
2004: Saini Simrat P S; Sonoda Junichiro; Xu Li; Toma David; Uppal Hirdesh; Mu Ying; Ren Songrong; Moore David D; Evans Ronald M; Xie Wen
A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification.
Molecular pharmacology 2004;65(2):292-300.
2004: Xu Wei; Cho Helen; Kadam Shilpa; Banayo Ester M; Anderson Scott; Yates John R; Emerson Beverly M; Evans Ronald M
A methylation-mediator complex in hormone signaling.
Genes & development 2004;18(2):144-56.
2004: Shi Yanhong; Chichung Lie D; Taupin Philippe; Nakashima Kinichi; Ray Jasodhara; Yu Ruth T; Gage Fred H; Evans Ronald M
Expression and function of orphan nuclear receptor TLX in adult neural stem cells.
Nature 2004;427(6969):78-83.
2004: Demarest Stephen J; Deechongkit Songpon; Dyson H Jane; Evans Ronald M; Wright Peter E
Packing, specificity, and mutability at the binding interface between the p160 coactivator and CREB-binding protein.
Protein science : a publication of the Protein Society 2004;13(1):203-10.
2003: Evans Ronald M
An interview with Ronald M. Evans, Ph.D. Investigator, the Salk Institute for Biological Studies.
Assay and drug development technologies 2003;1(6):749-54.
2003: He Weimin; Barak Yaacov; Hevener Andrea; Olson Peter; Liao Debbie; Le Jamie; Nelson Michael; Ong Estelita; Olefsky Jerrold M; Evans Ronald M
Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15712-7.
2003: Hevener Andrea L; He Weimin; Barak Yaacov; Le Jamie; Bandyopadhyay Gautam; Olson Peter; Wilkes Jason; Evans Ronald M; Olefsky Jerrold
Muscle-specific Pparg deletion causes insulin resistance.
Nature medicine 2003;9(12):1491-7.
2003: Lee Chih-Hao; Chawla Ajay; Urbiztondo Ned; Liao Debbie; Boisvert William A; Evans Ronald M; Curtiss Linda K
Transcriptional repression of atherogenic inflammation: modulation by PPARdelta.
Science (New York, N.Y.) 2003;302(5644):453-7.
2003: Saez Enrique; Olson Peter; Evans Ronald M
Genetic deficiency in Pparg does not alter development of experimental prostate cancer.
Nature medicine 2003;9(10):1265-6.
2003: Rosenfeld John M; Vargas Reynaldo; Xie Wen; Evans Ronald M
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor.
Molecular endocrinology (Baltimore, Md.) 2003;17(7):1268-82.
2003: Lee Chih-Hao; Olson Peter; Evans Ronald M
Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors.
Endocrinology 2003;144(6):2201-7.
2003: Downes Michael; Verdecia Mark A; Roecker A J; Hughes Robert; Hogenesch John B; Kast-Woelbern Heidi R; Bowman Marianne E; Ferrer Jean-Luc; Anisfeld Andrew M; Edwards Peter A; Rosenfeld John M; Alvarez Jacqueline G A; Noel Joseph P; Nicolaou K C; Evans Ronald M
A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR.
Molecular cell 2003;11(4):1079-92.
2003: Wang Yong-Xu; Lee Chih-Hao; Tiep Sambath; Yu Ruth T; Ham Jungyeob; Kang Heonjoong; Evans Ronald M
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity.
Cell 2003;113(2):159-70.
2003: Gearhart Micah D; Holmbeck Signe M A; Evans Ronald M; Dyson H Jane; Wright Peter E
Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition.
Journal of molecular biology 2003;327(4):819-32.
2003: Xie Wen; Yeuh Mei-Fei; Radominska-Pandya Anna; Saini Simrat P S; Negishi Yoichi; Bottroff Bobbie Sue; Cabrera Geraldine Y; Tukey Robert H; Evans Ronald M
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4150-5.
2003: Nicolaou K C; Evans Ronald M; Roecker A J; Hughes Robert; Downes Michael; Pfefferkorn Jeffery A
Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries.
Organic & biomolecular chemistry 2003;1(6):908-20.
2003: Stenman Jan; Yu Ruth T; Evans Ronald M; Campbell Kenneth
Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon.
Development (Cambridge, England) 2003;130(6):1113-22.
2003: Miles Philip D G; Barak Yaacov; Evans Ronald M; Olefsky Jerrold M
Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding.
American journal of physiology. Endocrinology and metabolism 2003;284(3):E618-26.
2003: Sonoda J; Rosenfeld J M; Xu L; Evans R M; Xie W
A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection.
Current drug metabolism 2003;4(1):59-72.
2003: Chawla Ajay; Lee Chih-Hao; Barak Yaacov; He Weimin; Rosenfeld John; Liao Debbie; Han Jungyeob; Kang Heonjoong; Evans Ronald M
PPARdelta is a very low-density lipoprotein sensor in macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1268-73.
2003: Kao Hung-Ying; Han Chris C; Komar Anton A; Evans Ronald M
Co-repressor release but not ligand binding is a prerequisite for transcription activation by human retinoid acid receptor alpha ligand-binding domain.
The Journal of biological chemistry 2003;278(9):7366-73.
2003: Xu Wei; Cho Helen; Evans Ronald M
Acetylation and methylation in nuclear receptor gene activation.
Methods in enzymology 2003;364():205-23.
2002: Sonoda Junichiro; Xie Wen; Rosenfeld John M; Barwick Joyce L; Guzelian Philip S; Evans Ronald M
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13801-6.
2002: Lee Chih-Hao; Evans Ronald M
Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis.
Trends in endocrinology and metabolism: TEM 2002;13(8):331-5.
2002: Makishima Makoto; Lu Timothy T; Xie Wen; Whitfield G Kerr; Domoto Hideharu; Evans Ronald M; Haussler Mark R; Mangelsdorf David J
Vitamin D receptor as an intestinal bile acid sensor.
Science (New York, N.Y.) 2002;296(5571):1313-6.
2002: Xie Wen; Evans Ronald M
Pharmaceutical use of mouse models humanized for the xenobiotic receptor.
Drug discovery today 2002;7(9):509-15.
2002: Pitman Jeffrey L; Tsai Chih-Cheng; Edeen Philip T; Finley Kim D; Evans Ronald M; McKeown Michael
DSF nuclear receptor acts as a repressor in culture and in vivo.
Developmental biology 2002;245(2):315-28.
2002: Shi Yanhong; Hon Michelle; Evans Ronald M
The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2613-8.
2002: Love James D; Gooch John T; Benko Szilvia; Li Chuan; Nagy Laszlo; Chatterjee V Krishna K; Evans Ronald M; Schwabe John W R
The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12.
The Journal of biological chemistry 2002;277(13):11385-91.
2002: Tini Marc; Benecke Arndt; Um Soo-Joong; Torchia Joseph; Evans Ronald M; Chambon Pierre
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription.
Molecular cell 2002;9(2):265-77.
2002: Demarest Stephen J; Martinez-Yamout Maria; Chung John; Chen Hongwu; Xu Wei; Dyson H Jane; Evans Ronald M; Wright Peter E
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.
Nature 2002;415(6871):549-53.
2002: Barak Yaacov; Liao Debbie; He Weimin; Ong Estelita S; Nelson Michael C; Olefsky Jerrold M; Boland Richard; Evans Ronald M
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):303-8.
2002: Kao Hung-Ying; Lee Chih-Hao; Komarov Andrei; Han Chris C; Evans Ronald M
Isolation and characterization of mammalian HDAC10, a novel histone deacetylase.
The Journal of biological chemistry 2002;277(1):187-93.
2001: Xu W; Chen H; Du K; Asahara H; Tini M; Emerson B M; Montminy M; Evans R M
A transcriptional switch mediated by cofactor methylation.
Science (New York, N.Y.) 2001;294(5551):2507-11.
2001: Chawla A; Repa J J; Evans R M; Mangelsdorf D J
Nuclear receptors and lipid physiology: opening the X-files.
Science (New York, N.Y.) 2001;294(5548):1866-70.
2001: Lin R J; Sternsdorf T; Tini M; Evans R M
Transcriptional regulation in acute promyelocytic leukemia.
Oncogene 2001;20(49):7204-15.
2001: Xie W; Evans R M
Orphan nuclear receptors: the exotics of xenobiotics.
The Journal of biological chemistry 2001;276(41):37739-42.
2001: Misner D L; Jacobs S; Shimizu Y; de Urquiza A M; Solomin L; Perlmann T; De Luca L M; Stevens C F; Evans R M
Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11714-9.
2001: Shi Y; Downes M; Xie W; Kao H Y; Ordentlich P; Tsai C C; Hon M; Evans R M
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation.
Genes & development 2001;15(9):1140-51.
2001: Ghbeish N; Tsai C C; Schubiger M; Zhou J Y; Evans R M; McKeown M
The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3867-72.
2001: Xie W; Radominska-Pandya A; Shi Y; Simon C M; Nelson M C; Ong E S; Waxman D J; Evans R M
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3375-80.
2001: Clayton G M; Peak-Chew S Y; Evans R M; Schwabe J W
The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1549-54.
2001: Chawla A; Boisvert W A; Lee C H; Laffitte B A; Barak Y; Joseph S B; Liao D; Nagy L; Edwards P A; Curtiss L K; Evans R M; Tontonoz P
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis.
Molecular cell 2001;7(1):161-71.
2001: Chawla A; Barak Y; Nagy L; Liao D; Tontonoz P; Evans R M
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation.
Nature medicine 2001;7(1):48-52.
2001: Ordentlich P; Downes M; Evans R M
Corepressors and nuclear hormone receptor function.
Current topics in microbiology and immunology 2001;254():101-16.
2000: Xie W; Barwick J L; Simon C M; Pierce A M; Safe S; Blumberg B; Guzelian P S; Evans R M
Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
Genes & development 2000;14(23):3014-23.
2000: Saez E; Nelson M C; Eshelman B; Banayo E; Koder A; Cho G J; Evans R M
Identification of ligands and coligands for the ecdysone-regulated gene switch.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14512-7.
2000: Chawla A; Saez E; Evans R M
"Don't know much bile-ology".
Cell 2000;103(1):1-4.
2000: Lee H; Shi W; Tontonoz P; Wang S; Subbanagounder G; Hedrick C C; Hama S; Borromeo C; Evans R M; Berliner J A; Nagy L
Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells.
Circulation research 2000;87(6):516-21.
2000: Downes M; Ordentlich P; Kao H Y; Alvarez J G; Evans R M
Identification of a nuclear domain with deacetylase activity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10330-5.
2000: Xie W; Barwick J L; Downes M; Blumberg B; Simon C M; Nelson M C; Neuschwander-Tetri B A; Brunt E M; Guzelian P S; Evans R M
Humanized xenobiotic response in mice expressing nuclear receptor SXR.
Nature 2000;406(6794):435-9.
2000: Takada I; Yu R T; Xu H E; Lambert M H; Montana V G; Kliewer S A; Evans R M; Umesono K
Alteration of a single amino acid in peroxisome proliferator-activated receptor-alpha (PPAR alpha) generates a PPAR delta phenotype.
Molecular endocrinology (Baltimore, Md.) 2000;14(5):733-40.
2000: Yu R T; Chiang M Y; Tanabe T; Kobayashi M; Yasuda K; Evans R M; Umesono K
The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2621-5.
2000: Miles P D; Barak Y; He W; Evans R M; Olefsky J M
Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency.
The Journal of clinical investigation 2000;105(3):287-92.
2000: Kao H Y; Downes M; Ordentlich P; Evans R M
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.
Genes & development 2000;14(1):55-66.
1999: Nagy L; Kao H Y; Love J D; Li C; Banayo E; Gooch J T; Krishna V; Chatterjee K; Evans R M; Schwabe J W
Mechanism of corepressor binding and release from nuclear hormone receptors.
Genes & development 1999;13(24):3209-16.
1999: Xie W; Hong H; Yang N N; Lin R J; Simon C M; Stallcup M R; Evans R M
Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2.
Molecular endocrinology (Baltimore, Md.) 1999;13(12):2151-62.
1999: Asahara H; Dutta S; Kao H Y; Evans R M; Montminy M
Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner.
Molecular and cellular biology 1999;19(12):8219-25.
1999: Barak Y; Nelson M C; Ong E S; Jones Y Z; Ruiz-Lozano P; Chien K R; Koder A; Evans R M
PPAR gamma is required for placental, cardiac, and adipose tissue development.
Molecular cell 1999;4(4):585-95.
1999: Tsukui T; Capdevila J; Tamura K; Ruiz-Lozano P; Rodriguez-Esteban C; Yonei-Tamura S; Magallón J; Chandraratna R A; Chien K; Blumberg B; Evans R M; Belmonte J C
Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11376-81.
1999: Chen H; Lin R J; Xie W; Wilpitz D; Evans R M
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase.
Cell 1999;98(5):675-86.
1999: Tsai C C; Kao H Y; Yao T P; McKeown M; Evans R M
SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.
Molecular cell 1999;4(2):175-86.
1999: Egan D A; Evans R M
Target acquisition and acute promyelocytic leukemia.
The Journal of clinical investigation 1999;103(10):1367-8.
1999: Lin R J; Egan D A; Evans R M
Molecular genetics of acute promyelocytic leukemia.
Trends in genetics : TIG 1999;15(5):179-84.
1999: Ordentlich P; Downes M; Xie W; Genin A; Spinner N B; Evans R M
Unique forms of human and mouse nuclear receptor corepressor SMRT.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2639-44.
1999: Doucas V; Tini M; Egan D A; Evans R M
Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2627-32.
1999: Chakravarti D; Ogryzko V; Kao H Y; Nash A; Chen H; Nakatani Y; Evans R M
A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity.
Cell 1999;96(3):393-403.
1998: Chiang M Y; Misner D; Kempermann G; Schikorski T; Giguère V; Sucov H M; Gage F H; Stevens C F; Evans R M
An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression.
Neuron 1998;21(6):1353-61.
1998: Blumberg B; Sabbagh W; Juguilon H; Bolado J; van Meter C M; Ong E S; Evans R M
SXR, a novel steroid and xenobiotic-sensing nuclear receptor.
Genes & development 1998;12(20):3195-205.
1998: Blumberg B; Evans R M
Orphan nuclear receptors--new ligands and new possibilities.
Genes & development 1998;12(20):3149-55.
1998: Forman B M; Tzameli I; Choi H S; Chen J; Simha D; Seol W; Evans R M; Moore D D
Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta.
Nature 1998;395(6702):612-5.
1998: Dhordain P; Lin R J; Quief S; Lantoine D; Kerckaert J P; Evans R M; Albagli O
The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression.
Nucleic acids research 1998;26(20):4645-51.
1998: Saez E; Tontonoz P; Nelson M C; Alvarez J G; Ming U T; Baird S M; Thomazy V A; Evans R M
Activators of the nuclear receptor PPARgamma enhance colon polyp formation.
Nature medicine 1998;4(9):1058-61.
1998: Ryan A K; Blumberg B; Rodriguez-Esteban C; Yonei-Tamura S; Tamura K; Tsukui T; de la Peña J; Sabbagh W; Greenwald J; Choe S; Norris D P; Robertson E J; Evans R M; Rosenfeld M G; Izpisúa Belmonte J C
Pitx2 determines left-right asymmetry of internal organs in vertebrates.
Nature 1998;394(6693):545-51.
1998: Kao H Y; Ordentlich P; Koyano-Nakagawa N; Tang Z; Downes M; Kintner C R; Evans R M; Kadesch T
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway.
Genes & development 1998;12(15):2269-77.
1998: Blumberg B; Kang H; Bolado J; Chen H; Craig A G; Moreno T A; Umesono K; Perlmann T; De Robertis E M; Evans R M
BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites.
Genes & development 1998;12(9):1269-77.
1998: Tontonoz P; Nagy L; Alvarez J G; Thomazy V A; Evans R M
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL.
Cell 1998;93(2):241-52.
1998: Nagy L; Tontonoz P; Alvarez J G; Chen H; Evans R M
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma.
Cell 1998;93(2):229-40.
1998: LaMorte V J; Dyck J A; Ochs R L; Evans R M
Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):4991-6.
1998: Lin R J; Nagy L; Inoue S; Shao W; Miller W H; Evans R M
Role of the histone deacetylase complex in acute promyelocytic leukaemia.
Nature 1998;391(6669):811-4.
1998: Ruiz-Lozano P; Smith S M; Perkins G; Kubalak S W; Boss G R; Sucov H M; Evans R M; Chien K R
Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos.
Development (Cambridge, England) 1998;125(3):533-44.
1998: Lin R J; Kao H Y; Ordentlich P; Evans R M
The transcriptional basis of steroid physiology.
Cold Spring Harbor symposia on quantitative biology 1998;63():577-85.
1997: Li C; Evans R M
Ligation independent cloning irrespective of restriction site compatibility.
Nucleic acids research 1997;25(20):4165-6.
1997: Dhordain P; Albagli O; Lin R J; Ansieau S; Quief S; Leutz A; Kerckaert J P; Evans R M; Leprince D
Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):10762-7.
1997: Forman B M; Ruan B; Chen J; Schroepfer G J; Evans R M
The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):10588-93.
1997: Chen H; Lin R J; Schiltz R L; Chakravarti D; Nash A; Nagy L; Privalsky M L; Nakatani Y; Evans R M
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.
Cell 1997;90(3):569-80.
1997: Perlmann T; Evans R M
Nuclear receptors in Sicily: all in the famiglia.
Cell 1997;90(3):391-7.
1997: Sem D S; Casimiro D R; Kliewer S A; Provencal J; Evans R M; Wright P E
NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein.
The Journal of biological chemistry 1997;272(29):18038-43.
1997: Zelhof A C; Ghbeish N; Tsai C; Evans R M; McKeown M
A role for ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation.
Development (Cambridge, England) 1997;124(13):2499-506.
1997: Lee R Y; Luo J; Evans R M; Giguere V; Sucov H M
Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations.
Circulation research 1997;80(6):757-64.
1997: Nagy L; Kao H Y; Chakravarti D; Lin R J; Hassig C A; Ayer D E; Schreiber S L; Evans R M
Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase.
Cell 1997;89(3):373-80.
1997: Forman B M; Chen J; Evans R M
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4312-7.
1997: Li C; Schwabe J W; Banayo E; Evans R M
Coexpression of nuclear receptor partners increases their solubility and biological activities.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2278-83.
1997: Blumberg B; Bolado J; Moreno T A; Kintner C; Evans R M; Papalopulu N
An essential role for retinoid signaling in anteroposterior neural patterning.
Development (Cambridge, England) 1997;124(2):373-9.
1997: Tontonoz P; Singer S; Forman B M; Sarraf P; Fletcher J A; Fletcher C D; Brun R P; Mueller E; Altiok S; Oppenheim H; Evans R M; Spiegelman B M
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):237-41.
1996: Doucas V; Evans R M
The PML nuclear compartment and cancer.
Biochimica et biophysica acta 1996;1288(3):M25-9.
1996: Forman B M; Chen J; Evans R M
The peroxisome proliferator-activated receptors: ligands and activators.
Annals of the New York Academy of Sciences 1996;804():266-75.
1996: Gruber P J; Kubalak S W; Pexieder T; Sucov H M; Evans R M; Chien K R
RXR alpha deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice.
The Journal of clinical investigation 1996;98(6):1332-43.
1996: Chakravarti D; LaMorte V J; Nelson M C; Nakajima T; Schulman I G; Juguilon H; Montminy M; Evans R M
Role of CBP/P300 in nuclear receptor signalling.
Nature 1996;383(6595):99-103.
1996: Perlmann T; Umesono K; Rangarajan P N; Forman B M; Evans R M
Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors.
Molecular endocrinology (Baltimore, Md.) 1996;10(8):958-66.
1996: Early E; Moore M A; Kakizuka A; Nason-Burchenal K; Martin P; Evans R M; Dmitrovsky E
Transgenic expression of PML/RARalpha impairs myelopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7900-4.
1996: Chen J D; Umesono K; Evans R M
SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7567-71.
1996: Schulman I G; Juguilon H; Evans R M
Activation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states.
Molecular and cellular biology 1996;16(7):3807-13.
1996: Giguere V; Fawcett D; Luo J; Evans R M; Sucov H M
Genetic analysis of the retinoid signal.
Annals of the New York Academy of Sciences 1996;785():12-22.
1996: Achkar C C; Derguini F; Blumberg B; Langston A; Levin A A; Speck J; Evans R M; Bolado J; Nakanishi K; Buck J; Gudas L J
4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4879-84.
1996: Blumberg B; Bolado J; Derguini F; Craig A G; Moreno T A; Chakravarti D; Heyman R A; Buck J; Evans R M
Novel retinoic acid receptor ligands in Xenopus embryos.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4873-8.
1996: No D; Yao T P; Evans R M
Ecdysone-inducible gene expression in mammalian cells and transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3346-51.
1996: Brun R P; Tontonoz P; Forman B M; Ellis R; Chen J; Evans R M; Spiegelman B M
Differential activation of adipogenesis by multiple PPAR isoforms.
Genes & development 1996;10(8):974-84.
1996: Luo J; Sucov H M; Bader J A; Evans R M; Giguère V
Compound mutants for retinoic acid receptor (RAR) beta and RAR alpha 1 reveal developmental functions for multiple RAR beta isoforms.
Mechanisms of development 1996;55(1):33-44.
1996: Ogura T; Alvarez I S; Vogel A; Rodríguez C; Evans R M; Izpisúa Belmonte J C
Evidence that Shh cooperates with a retinoic acid inducible co-factor to establish ZPA-like activity.
Development (Cambridge, England) 1996;122(2):537-42.
1996: Parker D; Ferreri K; Nakajima T; LaMorte V J; Evans R; Koerber S C; Hoeger C; Montminy M R
Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism.
Molecular and cellular biology 1996;16(2):694-703.
1996: Doucas V; Ishov A M; Romo A; Juguilon H; Weitzman M D; Evans R M; Maul G G
Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.
Genes & development 1996;10(2):196-207.
1996: Sucov H M; Lou J; Gruber P J; Kubalak S W; Dyson E; Gumeringer C L; Lee R Y; Moles S A; Chien K R; Giguere V; Evans R M
The molecular genetics of retinoic acid receptors: cardiovascular and limb development.
Biochemical Society symposium 1996;62():143-56.
1995: Sucov H M; Izpisúa-Belmonte J C; Gañan Y; Evans R M
Mouse embryos lacking RXR alpha are resistant to retinoic-acid-induced limb defects.
Development (Cambridge, England) 1995;121(12):3997-4003.
1995: Zelhof A C; Yao T P; Chen J D; Evans R M; McKeown M
Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo.
Molecular and cellular biology 1995;15(12):6736-45.
1995: Mangelsdorf D J; Evans R M
The RXR heterodimers and orphan receptors.
Cell 1995;83(6):841-50.
1995: Mangelsdorf D J; Thummel C; Beato M; Herrlich P; Schütz G; Umesono K; Blumberg B; Kastner P; Mark M; Chambon P; Evans R M
The nuclear receptor superfamily: the second decade.
Cell 1995;83(6):835-9.
1995: Forman B M; Tontonoz P; Chen J; Brun R P; Spiegelman B M; Evans R M
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma.
Cell 1995;83(5):803-12.
1995: Stern C D; Yu R T; Kakizuka A; Kintner C R; Mathews L S; Vale W W; Evans R M; Umesono K
Activin and its receptors during gastrulation and the later phases of mesoderm development in the chick embryo.
Developmental biology 1995;172(1):192-205.
1995: Zelhof A C; Yao T P; Evans R M; McKeown M
Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10477-81.
1995: Chen J D; Evans R M
A transcriptional co-repressor that interacts with nuclear hormone receptors.
Nature 1995;377(6548):454-7.
1995: Schulman I G; Chakravarti D; Juguilon H; Romo A; Evans R M
Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8288-92.
1995: Zhou M D; Sucov H M; Evans R M; Chien K R
Retinoid-dependent pathways suppress myocardial cell hypertrophy.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7391-5.
1995: Dyson E; Sucov H M; Kubalak S W; Schmid-Schönbein G W; DeLano F A; Evans R M; Ross J; Chien K R
Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7386-90.
1995: Dyck J A; Warrell R P; Evans R M; Miller W H
Rapid diagnosis of acute promyelocytic leukemia by immunohistochemical localization of PML/RAR-alpha protein.
Blood 1995;86(3):862-7.
1995: Forman B M; Goode E; Chen J; Oro A E; Bradley D J; Perlmann T; Noonan D J; Burka L T; McMorris T; Lamph W W; Evans R M; Weinberger C
Identification of a nuclear receptor that is activated by farnesol metabolites.
Cell 1995;81(5):687-93.
1995: Forman B M; Umesono K; Chen J; Evans R M
Unique response pathways are established by allosteric interactions among nuclear hormone receptors.
Cell 1995;81(4):541-50.
1995: Willy P J; Umesono K; Ong E S; Evans R M; Heyman R A; Mangelsdorf D J
LXR, a nuclear receptor that defines a distinct retinoid response pathway.
Genes & development 1995;9(9):1033-45.
1995: Sucov H M; Evans R M
Retinoic acid and retinoic acid receptors in development.
Molecular neurobiology 1995;10(2-3):169-84.
1995: Ogura T; Evans R M
Evidence for two distinct retinoic acid response pathways for HOXB1 gene regulation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):392-6.
1995: Ogura T; Evans R M
A retinoic acid-triggered cascade of HOXB1 gene activation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):387-91.
1994: Lee M S; Sem D S; Kliewer S A; Provencal J; Evans R M; Wright P E
NMR assignments and secondary structure of the retinoid X receptor alpha DNA-binding domain. Evidence for the novel C-terminal helix.
European journal of biochemistry / FEBS 1994;224(2):639-50.
1994: Forman B M; Chen J; Blumberg B; Kliewer S A; Henshaw R; Ong E S; Evans R M
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors.
Molecular endocrinology (Baltimore, Md.) 1994;8(9):1253-61.
1994: Yu R T; McKeown M; Evans R M; Umesono K
Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx.
Nature 1994;370(6488):375-9.
1994: Kliewer S A; Forman B M; Blumberg B; Ong E S; Borgmeyer U; Mangelsdorf D J; Umesono K; Evans R M
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7355-9.
1994: Sucov H M; Dyson E; Gumeringer C L; Price J; Chien K R; Evans R M
RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.
Genes & development 1994;8(9):1007-18.
1994: Almasan A; Mangelsdorf D J; Ong E S; Wahl G M; Evans R M
Chromosomal localization of the human retinoid X receptors.
Genomics 1994;20(3):397-403.
1994: Giguère V; Tini M; Flock G; Ong E; Evans R M; Otulakowski G
Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors.
Genes & development 1994;8(5):538-53.
1994: Dyck J A; Maul G G; Miller W H; Chen J D; Kakizuka A; Evans R M
A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein.
Cell 1994;76(2):333-43.
1994: Evans R M
The molecular basis of signaling by vitamin A and its metabolites.
Harvey lectures 1994;90():105-17.
1993: Yao T P; Forman B M; Jiang Z; Cherbas L; Chen J D; McKeown M; Cherbas P; Evans R M
Functional ecdysone receptor is the product of EcR and Ultraspiracle genes.
Nature 1993;366(6454):476-9.
1993: Perlmann T; Rangarajan P N; Umesono K; Evans R M
Determinants for selective RAR and TR recognition of direct repeat HREs.
Genes & development 1993;7(7B):1411-22.
1993: Lee M S; Kliewer S A; Provencal J; Wright P E; Evans R M
Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding.
Science (New York, N.Y.) 1993;260(5111):1117-21.
1993: Damm K; Heyman R A; Umesono K; Evans R M
Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2989-93.
1993: Mangelsdorf D J; Kliewer S A; Kakizuka A; Umesono K; Evans R M
Retinoid receptors.
Recent progress in hormone research 1993;48():99-121.
1992: Yao T P; Segraves W A; Oro A E; McKeown M; Evans R M
Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation.
Cell 1992;71(1):63-72.
1992: Rangarajan P N; Umesono K; Evans R M
Modulation of glucocorticoid receptor function by protein kinase A.
Molecular endocrinology (Baltimore, Md.) 1992;6(9):1451-7.
1992: Kliewer S A; Umesono K; Noonan D J; Heyman R A; Evans R M
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors.
Nature 1992;358(6389):771-4.
1992: Ghazal P; DeMattei C; Giulietti E; Kliewer S A; Umesono K; Evans R M
Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7630-4.
1992: Oro A E; McKeown M; Evans R M
The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis.
Development (Cambridge, England) 1992;115(2):449-62.
1992: Oro A E; McKeown M; Evans R M
The Drosophila nuclear receptors: new insight into the actions of nuclear receptors in development.
Current opinion in genetics & development 1992;2(2):269-74.
1992: Miller W H; Kakizuka A; Frankel S R; Warrell R P; DeBlasio A; Levine K; Evans R M; Dmitrovsky E
Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2694-8.
1992: Borrelli E; Sawchenko P E; Evans R M
Pituitary hyperplasia induced by ectopic expression of nerve growth factor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2764-8.
1992: Kakizuka A; Sebastian B; Borgmeyer U; Hermans-Borgmeyer I; Bolado J; Hunter T; Hoekstra M F; Evans R M
A mouse cdc25 homolog is differentially and developmentally expressed.
Genes & development 1992;6(4):578-90.
1992: Blumberg B; Mangelsdorf D J; Dyck J A; Bittner D A; Evans R M; De Robertis E M
Multiple retinoid-responsive receptors in a single cell: families of retinoid "X" receptors and retinoic acid receptors in the Xenopus egg.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2321-5.
1992: Mangelsdorf D J; Borgmeyer U; Heyman R A; Zhou J Y; Ong E S; Oro A E; Kakizuka A; Evans R M
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.
Genes & development 1992;6(3):329-44.
1992: Kliewer S A; Umesono K; Heyman R A; Mangelsdorf D J; Dyck J A; Evans R M
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1448-52.
1992: Kliewer S A; Umesono K; Mangelsdorf D J; Evans R M
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling.
Nature 1992;355(6359):446-9.
1992: Heyman R A; Mangelsdorf D J; Dyck J A; Stein R B; Eichele G; Evans R M; Thaller C
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor.
Cell 1992;68(2):397-406.
1991: Schüle R; Evans R M
Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper.
Trends in genetics : TIG 1991;7(11-12):377-81.
1991: Kakizuka A; Miller W H; Umesono K; Warrell R P; Frankel S R; Murty V V; Dmitrovsky E; Evans R M
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML.
Cell 1991;66(4):663-74.
1991: Mangelsdorf D J; Umesono K; Kliewer S A; Borgmeyer U; Ong E S; Evans R M
A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR.
Cell 1991;66(3):555-61.
1991: Schüle R; Rangarajan P; Yang N; Kliewer S; Ransone L J; Bolado J; Verma I M; Evans R M
Retinoic acid is a negative regulator of AP-1-responsive genes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6092-6.
1991: Umesono K; Murakami K K; Thompson C C; Evans R M
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors.
Cell 1991;65(7):1255-66.
1991: Yang N; Schüle R; Mangelsdorf D J; Evans R M
Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3559-63.
1991: Schüle R; Evans R M
Functional antagonism between oncoprotein c-Jun and steroid hormone receptors.
Cold Spring Harbor symposia on quantitative biology 1991;56():119-27.
1990: Oro A E; McKeown M; Evans R M
Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor.
Nature 1990;347(6290):298-301.
1990: Schüle R; Rangarajan P; Kliewer S; Ransone L J; Bolado J; Yang N; Verma I M; Evans R M
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor.
Cell 1990;62(6):1217-26.
1990: Sucov H M; Murakami K K; Evans R M
Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5392-6.
1990: Ishikawa T; Umesono K; Mangelsdorf D J; Aburatani H; Stanger B Z; Shibasaki Y; Imawari M; Evans R M; Takaku F
A functional retinoic acid receptor encoded by the gene on human chromosome 12.
Molecular endocrinology (Baltimore, Md.) 1990;4(6):837-44.
1990: Schüle R; Umesono K; Mangelsdorf D J; Bolado J; Pike J W; Evans R M
Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene.
Cell 1990;61(3):497-504.
1990: Mangelsdorf D J; Ong E S; Dyck J A; Evans R M
Nuclear receptor that identifies a novel retinoic acid response pathway.
Nature 1990;345(6272):224-9.
1989: Damm K; Thompson C C; Evans R M
Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist.
Nature 1989;339(6226):593-7.
1989: Borrelli E; Heyman R A; Arias C; Sawchenko P E; Evans R M
Transgenic mice with inducible dwarfism.
Nature 1989;339(6225):538-41.
1989: Umesono K; Evans R M
Determinants of target gene specificity for steroid/thyroid hormone receptors.
Cell 1989;57(7):1139-46.
1989: Thompson C C; Evans R M
Trans-activation by thyroid hormone receptors: functional parallels with steroid hormone receptors.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3494-8.
1989: Giguère V; Ong E S; Evans R M; Tabin C J
Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb.
Nature 1989;337(6207):566-9.
1989: Oro A E; Umesono K; Evans R M
Steroid hormone receptor homologs in development.
Development (Cambridge, England) 1989;107 Suppl():133-40.
1989: Evans R M
The v-erbA oncogene is a thyroid hormone receptor antagonist.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():26-8.
1988: Hollenberg S M; Evans R M
Multiple and cooperative trans-activation domains of the human glucocorticoid receptor.
Cell 1988;55(5):899-906.
1988: Oro A E; Hollenberg S M; Evans R M
Transcriptional inhibition by a glucocorticoid receptor-beta-galactosidase fusion protein.
Cell 1988;55(6):1109-14.
1988: Oro A E; Ong E S; Margolis J S; Posakony J W; McKeown M; Evans R M
The Drosophila gene knirps-related is a member of the steroid-receptor gene superfamily.
Nature 1988;336(6198):493-6.
1988: Arriza J L; Simerly R B; Swanson L W; Evans R M
The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response.
Neuron 1988;1(9):887-900.
1988: Umesono K; Giguere V; Glass C K; Rosenfeld M G; Evans R M
Retinoic acid and thyroid hormone induce gene expression through a common responsive element.
Nature 1988;336(6196):262-5.
1988: Borrelli E; Heyman R; Hsi M; Evans R M
Targeting of an inducible toxic phenotype in animal cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7572-6.
1988: Evans R M
The steroid and thyroid hormone receptor superfamily.
Science (New York, N.Y.) 1988;240(4854):889-95.
1988: Waterman M L; Adler S; Nelson C; Greene G L; Evans R M; Rosenfeld M G
A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene.
Molecular endocrinology (Baltimore, Md.) 1988;2(1):14-21.
1988: Giguère V; Yang N; Segui P; Evans R M
Identification of a new class of steroid hormone receptors.
Nature 1988;331(6151):91-4.
1988: Evans R M; Hollenberg S M
Zinc fingers: gilt by association.
Cell 1988;52(1):1-3.
1988: Rosenfeld M G; Crenshaw E B; Lira S A; Swanson L; Borrelli E; Heyman R; Evans R M
Transgenic mice: applications to the study of the nervous system.
Annual review of neuroscience 1988;11():353-72.
1987: Giguere V; Ong E S; Segui P; Evans R M
Identification of a receptor for the morphogen retinoic acid.
Nature 1987;330(6149):624-9.
1987: Glass C K; Franco R; Weinberger C; Albert V R; Evans R M; Rosenfeld M G
A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone.
Nature 1987;329(6141):738-41.
1987: Thompson C C; Weinberger C; Lebo R; Evans R M
Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system.
Science (New York, N.Y.) 1987;237(4822):1610-4.
1987: Arriza J L; Weinberger C; Cerelli G; Glaser T M; Handelin B L; Housman D E; Evans R M
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.
Science (New York, N.Y.) 1987;237(4812):268-75.
1987: Hollenberg S M; Giguere V; Segui P; Evans R M
Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor.
Cell 1987;49(1):39-46.
1987: Weinberger C; Giguère V; Hollenberg S M; Thompson C; Arriza J; Evans R M
Human steroid receptors and erb-A gene products form a superfamily of enhancer-binding proteins.
Clinical physiology and biochemistry 1987;5(3-4):179-89.
1986: Elsholtz H P; Mangalam H J; Potter E; Albert V R; Supowit S; Evans R M; Rosenfeld M G
Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters.
Science (New York, N.Y.) 1986;234(4783):1552-7.
1986: Weinberger C; Thompson C C; Ong E S; Lebo R; Gruol D J; Evans R M
The c-erb-A gene encodes a thyroid hormone receptor.
Nature 1986;324(6098):641-6.
1986: Weinberger C; Giguere V; Hollenberg S; Rosenfeld M G; Evans R M
Human steroid receptors and erbA proto-oncogene products: members of a new superfamily of enhancer binding proteins.
Cold Spring Harbor symposia on quantitative biology 1986;51 Pt 2():759-72.
1985: Weinberger C; Hollenberg S M; Rosenfeld M G; Evans R M
Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product.
Nature 1985;318(6047):670-2.
1985: Hollenberg S M; Weinberger C; Ong E S; Cerelli G; Oro A; Lebo R; Thompson E B; Rosenfeld M G; Evans R M
Primary structure and expression of a functional human glucocorticoid receptor cDNA.
Nature 1985;318(6047):635-41.
1985: Weinberger C; Hollenberg S M; Ong E S; Harmon J M; Brower S T; Cidlowski J; Thompson E B; Rosenfeld M G; Evans R M
Identification of human glucocorticoid receptor complementary DNA clones by epitope selection.
Science (New York, N.Y.) 1985;228(4700):740-2.
1985: Evans R M; Weinberger C; Hollenberg S; Swanson L; Nelson C; Rosenfeld M G
Inducible and developmental control of neuroendocrine genes.
Cold Spring Harbor symposia on quantitative biology 1985;50():389-97.

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