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Karla Ewalt

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Chemicals & Drugs

Physiology

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Neovascularization, Pathologic

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Mili Kapoor; Francella J Otero; Bonnie M Slike; Karla L Ewalt; Xiang-Lei Yang
Mutational separation of aminoacylation and cytokine activities of human tyrosyl-tRNA synthetase.
Gang Cheng; Hua Zhang; Xianglei Yang; Eleni Tzima; Karla L Ewalt; Paul Schimmel; James E Faber
Effect of mini-tyrosyl-tRNA synthetase on ischemic angiogenesis, leukocyte recruitment, and vascular permeability.
Xiang-Lei Yang; Mili Kapoor; Francella J Otero; Bonnie M Slike; Hiro Tsuruta; Ricardo F Frausto; Alison Bates; Karla L Ewalt; David A Cheresh; Paul Schimmel
Gain-of-function mutational activation of human tRNA synthetase procytokine.

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All Publications

2009: Mili Kapoor; Francella J Otero; Bonnie M Slike; Karla L Ewalt; Xiang-Lei Yang
Mutational separation of aminoacylation and cytokine activities of human tyrosyl-tRNA synthetase.
Chemistry & biology 2009;16(5):531-9.
2008: Gang Cheng; Hua Zhang; Xianglei Yang; Eleni Tzima; Karla L Ewalt; Paul Schimmel; James E Faber
Effect of mini-tyrosyl-tRNA synthetase on ischemic angiogenesis, leukocyte recruitment, and vascular permeability.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(4):R1138-46.
2007: Xiang-Lei Yang; Mili Kapoor; Francella J Otero; Bonnie M Slike; Hiro Tsuruta; Ricardo F Frausto; Alison Bates; Karla L Ewalt; David A Cheresh; Paul Schimmel
Gain-of-function mutational activation of human tRNA synthetase procytokine.
Chemistry & biology 2007;14(12):1323-33.
2007: Xiang-Lei Yang; MIN GUO; Mili Kapoor; Karla L Ewalt; Francella J Otero; Robert J Skene; Duncan E McRee; Paul Schimmel
Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase.
Structure (London, England : 1993) 2007;15(7):793-805.
2006: Xiang-Lei Yang; Francella J Otero; Karla L Ewalt; Jianming Liu; Manal A Swairjo; Caroline Köhrer; Uttam L RajBhandary; Robert J Skene; Duncan E McRee; Paul Schimmel
Two conformations of a crystalline human tRNA synthetase-tRNA complex: implications for protein synthesis.
The EMBO journal 2006;25(12):2919-29.
2005: Sang Gyu Park; Karla L Ewalt; Sunghoon Kim
Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers.
Trends in biochemical sciences 2005;30(10):569-74.
2005: Karla L Ewalt; Xiang-Lei Yang; Francella J Otero; Jianming Liu; Bonnie M Slike; Paul Schimmel
Variant of human enzyme sequesters reactive intermediate.
Biochemistry 2005;44(11):4216-21.
2005: Eleni Tzima; John Reader; Mohammad Irani-Tehrani; Karla L Ewalt; Martin A Schwartz; Paul Schimmel
VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function.
The Journal of biological chemistry 2005;280(4):2405-8.
2004: Paul Schimmel; Karla L Ewalt
Translation silenced by fused pair of tRNA synthetases.
Cell 2004;119(2):147-8.
2004: Xiang-Lei Yang; Paul Schimmel; Karla L Ewalt
Relationship of two human tRNA synthetases used in cell signaling.
Trends in biochemical sciences 2004;29(5):250-6.
2004: Jianming Liu; Eveline Shue; Karla L Ewalt; Paul Schimmel
A new gamma-interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase.
Nucleic acids research 2004;32(2):719-27.
2003: Eleni Tzima; John Reader; Mohammad Irani-Tehrani; Karla L Ewalt; Martin A Schwartz; Paul Schimmel
Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14903-7.
2002: Jianming Liu; Xiang-Lei Yang; Karla L Ewalt; Paul Schimmel
Mutational switching of a yeast tRNA synthetase into a mammalian-like synthetase cytokine.
Biochemistry 2002;41(48):14232-7.
2002: Karla L Ewalt; Paul Schimmel
Activation of angiogenic signaling pathways by two human tRNA synthetases.
Biochemistry 2002;41(45):13344-9.
2002: Atsushi Otani; Karen Kinder; Karla L Ewalt; Francella J Otero; Paul Schimmel; Martin Friedlander
Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis.
Nature medicine 2002;8(9):1004-10.
2002: Keisuke Wakasugi; Bonnie M Slike; John Hood; Karla L Ewalt; David A Cheresh; Paul Schimmel
Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase.
The Journal of biological chemistry 2002;277(23):20124-6.
2002: Keisuke Wakasugi; Bonnie M Slike; John Hood; Atsushi Otani; Karla L Ewalt; Martin Friedlander; David A Cheresh; Paul Schimmel
A human aminoacyl-tRNA synthetase as a regulator of angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):173-7.
2002: Atsushi Otani; Bonnie M Slike; Michael I Dorrell; John Hood; Karen Kinder; Karla L Ewalt; David A Cheresh; Paul Schimmel; Martin Friedlander
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):178-83.