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John Exton

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Physiology

Enzyme Activation

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Rats

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Phosphorylation

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Co-Publications
Name
19
Blackmore, Peter
11
Ho, Wan-Ting
8
Xie, Zhi
5
Williger, Ben-Tsion
5
Fleming, Ian
5
Kam, Yoonseok
5
Couvillon, Anthony
5
Min, DS
5
Provost, JJ
4
Park, SK
4
Hu, Tianhui
4
Shin, Ok-Ho
4
Buchanan, Gregory
3
Elliott, CM
3
Hess, JA

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Publications

TOP 3
Exton John H
In search of the message.
Brown H Alex; Henage Lee G; Preininger Anita M; Xiang Yun; Exton John H
Biochemical analysis of phospholipase D.
Couvillon Anthony D; Exton John H
Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells.

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All Publications

2008: Exton John H
In search of the message.
The Journal of biological chemistry 2008;283(22):14901-9.
2007: Brown H Alex; Henage Lee G; Preininger Anita M; Xiang Yun; Exton John H
Biochemical analysis of phospholipase D.
Methods in enzymology 2007;434():49-87.
2006: Couvillon Anthony D; Exton John H
Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells.
Cellular signalling 2006;18(5):715-28.
2006: Hu Ping; Han Zhang; Couvillon Anthony D; Kaufman Randal J; Exton John H
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.
Molecular and cellular biology 2006;26(8):3071-84.
2006: Henage Lee G; Exton John H; Brown H Alex
Kinetic analysis of a mammalian phospholipase D: allosteric modulation by monomeric GTPases, protein kinase C, and polyphosphoinositides.
The Journal of biological chemistry 2006;281(6):3408-17.
2005: Kook Seunghyi; Exton John H
Identification of interaction sites of protein kinase Calpha on phospholipase D1.
Cellular signalling 2005;17(11):1423-32.
2005: Chen Jun-Song; Exton John H
Sites on phospholipase D2 phosphorylated by PKCalpha.
Biochemical and biophysical research communications 2005;333(4):1322-6.
2005: Hu Tianhui; Exton John H
A point mutation at phenylalanine 663 abolishes protein kinase C alpha's ability to translocate to the perinuclear region and activate phospholipase D1.
Biochemical and biophysical research communications 2005;333(3):750-3.
2005: Ho Wan-Ting; Xie Zhi; Zhao Zhizhuang Joe; Exton John H
Tyrosine phosphorylation of phospholipase D1 by v-Src does not per se result in activation.
Cellular signalling 2005;17(6):691-9.
2005: Hiroyama Masami; Exton John H
Localization and regulation of phospholipase D2 by ARF6.
Journal of cellular biochemistry 2005;95(1):149-64.
2005: Buchanan F Gregory; McReynolds Matt; Couvillon Anthony; Kam Yoonseok; Holla Vijaykumar R; Dubois Raymond N; Exton John H
Requirement of phospholipase D1 activity in H-RasV12-induced transformation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1638-42.
2005: Hu Tianhui; Exton John H
1-Butanol interferes with phospholipase D1 and protein kinase Calpha association and inhibits phospholipase D1 basal activity.
Biochemical and biophysical research communications 2005;327(4):1047-51.
2005: Hiroyama Masami; Exton John H
Studies of the roles of ADP-ribosylation factors and phospholipase D in phorbol ester-induced membrane ruffling.
Journal of cellular physiology 2005;202(2):608-22.
2005: Shin Ok-Ho; Exton John H
Assays and properties of arfaptin 2 binding to Rac1 and ADP-ribosylation factors (Arfs).
Methods in enzymology 2005;404():359-67.
2004: Hu Ping; Han Zhang; Couvillon Anthony D; Exton John H
Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death.
The Journal of biological chemistry 2004;279(47):49420-9.
2004: Hu Tianhui; Exton John H
Protein kinase Calpha translocates to the perinuclear region to activate phospholipase D1.
The Journal of biological chemistry 2004;279(34):35702-8.
2004: Chen Jun-Song; Exton John H
Regulation of phospholipase D2 activity by protein kinase C alpha.
The Journal of biological chemistry 2004;279(21):22076-83.
2004: Kam Yoonseok; Exton John H
Role of phospholipase D in the activation of protein kinase D by lysophosphatidic acid.
Biochemical and biophysical research communications 2004;315(1):139-43.
2004: Kam Yoonseok; Exton John H
Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):311-9.
2003: Ho Wan-Ting; Exton John H; Williger Ben-Tsion
Arfaptin 1 inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in HT 1080 fibrosarcoma cells.
FEBS letters 2003;537(1-3):91-5.
2003: Hu Tianhui; Exton John H
Mechanisms of regulation of phospholipase D1 by protein kinase Calpha.
The Journal of biological chemistry 2003;278(4):2348-55.
2002: Exton John H
Regulation of phospholipase D.
FEBS letters 2002;531(1):58-61.
2002: Xie Zhi; Ho Wan-Ting; Spellman Rachel; Cai Songmin; Exton John H
Mechanisms of regulation of phospholipase D1 and D2 by the heterotrimeric G proteins G13 and Gq.
The Journal of biological chemistry 2002;277(14):11979-86.
2002: Xie Zhi; Ho Wan-Ting; Exton John H
Functional implications of post-translational modifications of phospholipases D1 and D2.
Biochimica et biophysica acta 2002;1580(1):9-21.
2002: Kam Yoonseok; Exton John H
Dimerization of phospholipase d isozymes.
Biochemical and biophysical research communications 2002;290(1):375-80.
2002: Exton J H
Phospholipase D-structure, regulation and function.
Reviews of physiology, biochemistry and pharmacology 2002;144():1-94.
2002: Xie Zhi; Kim Ha Kun; Exton John H
Expression and characterization of rat brain phospholipase D.
Methods in enzymology 2002;345():255-64.
2001: Shin O H; Couvillon A D; Exton J H
Arfophilin is a common target of both class II and class III ADP-ribosylation factors.
Biochemistry 2001;40(36):10846-52.
2001: Shin O H; Exton J H
Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1.
Biochemical and biophysical research communications 2001;285(5):1267-73.
2001: Kam Y; Exton J H
Phospholipase D activity is required for actin stress fiber formation in fibroblasts.
Molecular and cellular biology 2001;21(12):4055-66.
2001: Cai S; Exton J H
Determination of interaction sites of phospholipase D1 for RhoA.
The Biochemical journal 2001;355(Pt 3):779-85.
2001: Xie Z; Ho W T; Exton J H
Requirements and effects of palmitoylation of rat PLD1.
The Journal of biological chemistry 2001;276(12):9383-91.
2000: Xie Z; Ho W T; Exton J H
Conserved amino acids at the C-terminus of rat phospholipase D1 are essential for enzymatic activity.
European journal of biochemistry / FEBS 2000;267(24):7138-46.
2000: Jin S; Exton J H
Activation of RhoA by association of Galpha(13) with Dbl.
Biochemical and biophysical research communications 2000;277(3):718-21.
2000: Xie Z; Ho W T; Exton J H
Association of the N- and C-terminal domains of phospholipase D. Contribution of the conserved HKD motifs to the interaction and the requirement of the association for Ser/Thr phosphorylation of the enzyme.
The Journal of biological chemistry 2000;275(32):24962-9.
2000: Exton J H
Phospholipase D.
Annals of the New York Academy of Sciences 2000;905():61-8.
2000: Buchanan F G; Elliot C M; Gibbs M; Exton J H
Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid.
The Journal of biological chemistry 2000;275(13):9742-8.
2000: Hess J A; Buchanan F G; Ryder S; Exton J H
Altered activation of phospholipase D by lysophosphatidic acid and endothelin-1 in mouse embryo fibroblasts lacking phospholipase C-gamma1.
Cellular signalling 2000;12(1):37-45.
1999: Shin O H; Ross A H; Mihai I; Exton J H
Identification of arfophilin, a target protein for GTP-bound class II ADP-ribosylation factors.
The Journal of biological chemistry 1999;274(51):36609-15.
1999: Exton J H
Regulation of phospholipase D.
Biochimica et biophysica acta 1999;1439(2):121-33.
1999: Williger B T; Provost J J; Ho W T; Milstine J; Exton J H
Arfaptin 1 forms a complex with ADP-ribosylation factor and inhibits phospholipase D.
FEBS letters 1999;454(1-2):85-9.
1999: Fleming I N; Elliott C M; Buchanan F G; Downes C P; Exton J H
Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation.
The Journal of biological chemistry 1999;274(18):12753-8.
1999: Williger B T; Ostermann J; Exton J H
Arfaptin 1, an ARF-binding protein, inhibits phospholipase D and endoplasmic reticulum/Golgi protein transport.
FEBS letters 1999;443(2):197-200.
1999: Williger B T; Ho W T; Exton J H
Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells.
The Journal of biological chemistry 1999;274(2):735-8.
1998: Xie Z; Ho W T; Exton J H
Association of N- and C-terminal domains of phospholipase D is required for catalytic activity.
The Journal of biological chemistry 1998;273(52):34679-82.
1998: Exton J H
Phospholipase D.
Biochimica et biophysica acta 1998;1436(1-2):105-15.
1998: Min D S; Kim E G; Exton J H
Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts.
The Journal of biological chemistry 1998;273(45):29986-94.
1998: Guillemain I; Exton J H
Role of rho proteins in agonist regulation of phospholipase D in HL-60 cells.
Biochimica et biophysica acta 1998;1405(1-3):161-70.
1998: Hess J A; Ji Q S; Carpenter G; Exton J H
Analysis of platelet-derived growth factor-induced phospholipase D activation in mouse embryo fibroblasts lacking phospholipase C-gamma1.
The Journal of biological chemistry 1998;273(32):20517-24.
1998: Exton J H
Small GTPases minireview series.
The Journal of biological chemistry 1998;273(32):19923.
1998: Min D S; Exton J H
Phospholipase D is associated in a phorbol ester-dependent manner with protein kinase C-alpha and with a 220-kDa protein which is phosphorylated on serine and threonine.
Biochemical and biophysical research communications 1998;248(3):533-7.
1998: Fleming I N; Elliott C M; Exton J H
Phospholipase C-gamma, protein kinase C and Ca2+/calmodulin-dependent protein kinase II are involved in platelet-derived growth factor-induced phosphorylation of Tiam1.
FEBS letters 1998;429(3):229-33.
1998: Bae C D; Min D S; Fleming I N; Exton J H
Determination of interaction sites on the small G protein RhoA for phospholipase D.
The Journal of biological chemistry 1998;273(19):11596-604.
1998: Park S K; Min D S; Exton J H
Definition of the protein kinase C interaction site of phospholipase D.
Biochemical and biophysical research communications 1998;244(2):364-7.
1998: Min D S; Park S K; Exton J H
Characterization of a rat brain phospholipase D isozyme.
The Journal of biological chemistry 1998;273(12):7044-51.
1998: Plonk S G; Park S K; Exton J H
The alpha-subunit of the heterotrimeric G protein G13 activates a phospholipase D isozyme by a pathway requiring Rho family GTPases.
The Journal of biological chemistry 1998;273(9):4823-6.
1997: Fleming I N; Elliott C M; Collard J G; Exton J H
Lysophosphatidic acid induces threonine phosphorylation of Tiam1 in Swiss 3T3 fibroblasts via activation of protein kinase C.
The Journal of biological chemistry 1997;272(52):33105-10.
1997: Guillemain I; Exton J H
Effects of brefeldin A on phosphatidylcholine phospholipase D and inositolphospholipid metabolism in HL-60 cells.
European journal of biochemistry / FEBS 1997;249(3):812-9.
1997: Park S K; Provost J J; Bae C D; Ho W T; Exton J H
Cloning and characterization of phospholipase D from rat brain.
The Journal of biological chemistry 1997;272(46):29263-71.
1997: Exton J H
New developments in phospholipase D.
The Journal of biological chemistry 1997;272(25):15579-82.
1997: Yeo E J; Provost J J; Exton J H
Dissociation of tyrosine phosphorylation and activation of phosphoinositide phospholipase C induced by the protein kinase C inhibitor Ro-31-8220 in Swiss 3T3 cells treated with platelet-derived growth factor.
Biochimica et biophysica acta 1997;1356(3):308-20.
1997: Exton J H
Phospholipase D: enzymology, mechanisms of regulation, and function.
Physiological reviews 1997;77(2):303-20.
1997: Vinggaard A M; Provost J J; Exton J H; Hansen H S
Arf and RhoA regulate both the cytosolic and the membrane-bound phospholipase D from human placenta.
Cellular signalling 1997;9(2):189-96.
1997: Kanoh H; Williger B T; Exton J H
Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes.
The Journal of biological chemistry 1997;272(9):5421-9.
1997: Exton J H
Cell signalling through guanine-nucleotide-binding regulatory proteins (G proteins) and phospholipases.
European journal of biochemistry / FEBS 1997;243(1-2):10-20.
1997: Hess J A; Ross A H; Qiu R G; Symons M; Exton J H
Role of Rho family proteins in phospholipase D activation by growth factors.
The Journal of biological chemistry 1997;272(3):1615-20.
1997: Exton J H
Regulation of phosphoinositide phospholipases by G-proteins.
Advances in experimental medicine and biology 1997;400A():3-8.
1996: Fleming I N; Elliott C M; Exton J H
Differential translocation of rho family GTPases by lysophosphatidic acid, endothelin-1, and platelet-derived growth factor.
The Journal of biological chemistry 1996;271(51):33067-73.
1996: Provost J J; Fudge J; Israelit S; Siddiqi A R; Exton J H
Tissue-specific distribution and subcellular distribution of phospholipase D in rat: evidence for distinct RhoA- and ADP-ribosylation factor (ARF)-regulated isoenzymes.
The Biochemical journal 1996;319 ( Pt 1)():285-91.
1996: Malcolm K C; Sable C L; Elliott C M; Exton J H
Enhanced phospholipase D activity and altered morphology in RhoA-overexpressing RAT1 fibroblasts.
Biochemical and biophysical research communications 1996;225(2):514-9.
1996: Pete M J; Exton J H
Purification of a lysophospholipase from bovine brain that selectively deacylates arachidonoyl-substituted lysophosphatidylcholine.
The Journal of biological chemistry 1996;271(30):18114-21.
1996: Malcolm K C; Elliott C M; Exton J H
Evidence for Rho-mediated agonist stimulation of phospholipase D in rat1 fibroblasts. Effects of Clostridium botulinum C3 exoenzyme.
The Journal of biological chemistry 1996;271(22):13135-9.
1996: Venkatakrishnan G; Exton J H
Identification of determinants in the alpha-subunit of Gq required for phospholipase C activation.
The Journal of biological chemistry 1996;271(9):5066-72.
1996: Pete M J; Wu D W; Exton J H
Subcellular fractions of bovine brain degrade phosphatidylcholine by sequential deacylation of the sn-1 and sn-2 positions.
Biochimica et biophysica acta 1996;1299(3):325-32.
1996: Exton J H
Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins.
Annual review of pharmacology and toxicology 1996;36():481-509.
1995: Malcolm K C; Trammell S E; Exton J H
Purinergic agonist and G protein stimulation of phospholipase D in rat liver plasma membranes. Independence from phospholipase C activation.
Biochimica et biophysica acta 1995;1268(2):152-8.
1995: Pete M J; Exton J H
Phospholipid interactions affect substrate hydrolysis by bovine brain phospholipase A1.
Biochimica et biophysica acta 1995;1256(3):367-73.
1995: Siddiqi A R; Smith J L; Ross A H; Qiu R G; Symons M; Exton J H
Regulation of phospholipase D in HL60 cells. Evidence for a cytosolic phospholipase D.
The Journal of biological chemistry 1995;270(15):8466-73.
1995: Yeo E J; Exton J H
Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells.
The Journal of biological chemistry 1995;270(8):3980-8.
1994: Yeo E J; Kazlauskas A; Exton J H
Activation of phospholipase C-gamma is necessary for stimulation of phospholipase D by platelet-derived growth factor.
The Journal of biological chemistry 1994;269(45):27823-6.
1994: Ha K S; Yeo E J; Exton J H
Lysophosphatidic acid activation of phosphatidylcholine-hydrolysing phospholipase D and actin polymerization by a pertussis toxin-sensitive mechanism.
The Biochemical journal 1994;303 ( Pt 1)():55-9.
1994: Malcolm K C; Ross A H; Qiu R G; Symons M; Exton J H
Activation of rat liver phospholipase D by the small GTP-binding protein RhoA.
The Journal of biological chemistry 1994;269(42):25951-4.
1994: Pete M J; Ross A H; Exton J H
Purification and properties of phospholipase A1 from bovine brain.
The Journal of biological chemistry 1994;269(30):19494-500.
1994: Exton J H
Phosphatidylcholine breakdown and signal transduction.
Biochimica et biophysica acta 1994;1212(1):26-42.
1994: Conricode K M; Smith J L; Burns D J; Exton J H
Phospholipase D activation in fibroblast membranes by the alpha and beta isoforms of protein kinase C.
FEBS letters 1994;342(2):149-53.
1994: Exton J H
Messenger molecules derived from membrane lipids.
Current opinion in cell biology 1994;6(2):226-9.
1994: Exton J H
Phosphoinositide phospholipases and G proteins in hormone action.
Annual review of physiology 1994;56():349-69.
1993: Ha K S; Exton J H
Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts.
The Journal of cell biology 1993;123(6 Pt 2):1789-96.
1993: Blank J L; Shaw K; Ross A H; Exton J H
Purification of a 110-kDa phosphoinositide phospholipase C that is activated by G-protein beta gamma-subunits.
The Journal of biological chemistry 1993;268(33):25184-91.
1993: Ha K S; Exton J H
Differential translocation of protein kinase C isozymes by thrombin and platelet-derived growth factor. A possible function for phosphatidylcholine-derived diacylglycerol.
The Journal of biological chemistry 1993;268(14):10534-9.
1993: Allan C J; Exton J H
Quantification of inositol phospholipid breakdown in isolated rat hepatocytes.
The Biochemical journal 1993;290 ( Pt 3)():865-72.
1993: Nakanishi H; Brewer K A; Exton J H
Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.
The Journal of biological chemistry 1993;268(1):13-6.
1993: Exton J H
Role of G proteins in activation of phosphoinositide phospholipase C.
Advances in second messenger and phosphoprotein research 1993;28():65-72.
1992: Siddiqui R A; Exton J H
Oleate stimulation of diacylglycerol formation from phosphatidylcholine through effects on phospholipase D and phosphatidate phosphohydrolase.
European journal of biochemistry / FEBS 1992;210(2):601-7.
1992: Blank J L; Brattain K A; Exton J H
Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits.
The Journal of biological chemistry 1992;267(32):23069-75.
1992: Nakanishi H; Exton J H
Purification and characterization of the zeta isoform of protein kinase C from bovine kidney.
The Journal of biological chemistry 1992;267(23):16347-54.
1992: Berstein G; Blank J L; Jhon D Y; Exton J H; Rhee S G; Ross E M
Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator.
Cell 1992;70(3):411-8.
1992: Shaw K; Exton J H
Identification in bovine liver plasma membranes of a Gq-activatable phosphoinositide phospholipase C.
Biochemistry 1992;31(27):6347-54.
1992: Conricode K M; Brewer K A; Exton J H
Activation of phospholipase D by protein kinase C. Evidence for a phosphorylation-independent mechanism.
The Journal of biological chemistry 1992;267(11):7199-202.
1992: Berstein G; Blank J L; Smrcka A V; Higashijima T; Sternweis P C; Exton J H; Ross E M
Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.
The Journal of biological chemistry 1992;267(12):8081-8.
1992: Siddiqui R A; Exton J H
Phospholipid base exchange activity in rat liver plasma membranes. Evidence for regulation by G-protein and P2y-purinergic receptor.
The Journal of biological chemistry 1992;267(9):5755-61.
1992: Exton J H; Taylor S J; Blank J S; Bocckino S B
Regulation of phosphoinositide and phosphatidylcholine phospholipases by G proteins.
Ciba Foundation symposium 1992;164():36-42; discussion 43-9.
1991: Stewart S J; Cunningham G R; Strupp J A; House F S; Kelley L L; Henderson G S; Exton J H; Bocckino S B
Activation of phospholipase D: a signaling system set in motion by perturbation of the T lymphocyte antigen receptor/CD3 complex.
Cell regulation 1991;2(10):841-50.
1991: Blank J L; Ross A H; Exton J H
Purification and characterization of two G-proteins that activate the beta 1 isozyme of phosphoinositide-specific phospholipase C. Identification as members of the Gq class.
The Journal of biological chemistry 1991;266(27):18206-16.
1991: Bocckino S B; Wilson P B; Exton J H
Phosphatidate-dependent protein phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6210-3.
1991: Wange R L; Smrcka A V; Sternweis P C; Exton J H
Photoaffinity labeling of two rat liver plasma membrane proteins with [32P]gamma-azidoanilido GTP in response to vasopressin. Immunologic identification as alpha subunits of the Gq class of G proteins.
The Journal of biological chemistry 1991;266(18):11409-12.
1991: Exton J H; Taylor S J; Augert G; Bocckino S B
Cell signalling through phospholipid breakdown.
Molecular and cellular biochemistry 1991;104(1-2):81-6.
1991: Taylor S J; Chae H Z; Rhee S G; Exton J H
Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins.
Nature 1991;350(6318):516-8.
1990: Bouscarel B; Augert G; Taylor S J; Exton J H
Alterations in vasopressin and angiotensin II receptors and responses during culture of rat liver cells.
Biochimica et biophysica acta 1990;1055(3):265-72.
1990: Georgoussi Z; Taylor S J; Bocckino S B; Exton J H
Purification of the hepatic vasopressin receptor using a novel affinity column.
Biochimica et biophysica acta 1990;1055(1):69-74.
1990: Taylor S J; Smith J A; Exton J H
Purification from bovine liver membranes of a guanine nucleotide-dependent activator of phosphoinositide-specific phospholipase C. Immunologic identification as a novel G-protein alpha subunit.
The Journal of biological chemistry 1990;265(28):17150-6.
1990: Exton J H
Signaling through phosphatidylcholine breakdown.
The Journal of biological chemistry 1990;265(1):1-4.
1990: Exton J H
Hormonal regulation of phosphatidylcholine breakdown.
Advances in second messenger and phosphoprotein research 1990;24():152-7.
1989: Augert G; Bocckino S B; Blackmore P F; Exton J H
Hormonal stimulation of diacylglycerol formation in hepatocytes. Evidence for phosphatidylcholine breakdown.
The Journal of biological chemistry 1989;264(36):21689-98.
1989: Bocckino S B; Wilson P B; Exton J H
An early elevation of diacylglycerol and phosphatidate in regenerating liver.
Biochemical and biophysical research communications 1989;164(1):290-4.
1989: Bocckino S B; Wilson P; Exton J H
An enzymatic assay for picomole levels of phosphatidate.
Analytical biochemistry 1989;180(1):24-7.
1989: Lynch C J; Blackmore P F; Johnson E H; Wange R L; Krone P K; Exton J H
Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides.
The Journal of clinical investigation 1989;83(6):2050-62.
1989: Augert G; Blackmore P F; Exton J H
Changes in the concentration and fatty acid composition of phosphoinositides induced by hormones in hepatocytes.
The Journal of biological chemistry 1989;264(5):2574-80.
1989: Stewart S J; Prpic V; Johns J A; Powers F S; Graber S E; Forbes J T; Exton J H
Bacterial toxins affect early events of T lymphocyte activation.
The Journal of clinical investigation 1989;83(1):234-42.
1988: Bouscarel B; Wilson P B; Blackmore P F; Lynch C J; Exton J H
Agonist-induced down-regulation of the angiotensin II receptor in primary cultures of rat hepatocytes.
The Journal of biological chemistry 1988;263(29):14920-4.
1988: Bouscarel B; Blackmore P F; Exton J H
Characterization of the angiotensin II receptor in primary cultures of rat hepatocytes. Evidence that a single population is coupled to two different responses.
The Journal of biological chemistry 1988;263(29):14913-9.
1988: Exton J H
Mechanisms of action of calcium-mobilizing agonists: some variations on a young theme.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(11):2670-6.
1988: Bouscarel B; Meurer K; Decker C; Exton J H
The role of protein kinase C in the inactivation of hepatic glycogen synthase by calcium-mobilizing agonists.
The Biochemical journal 1988;251(1):47-53.
1988: Augert G; Exton J H
Insulin and oxytocin effects on phosphoinositide metabolism in adipocytes.
The Journal of biological chemistry 1988;263(8):3600-9.
1988: Lynch C J; Taylor S J; Smith J A; Exton J H
Formation of the high-affinity agonist state of the alpha 1-adrenergic receptor at cold temperatures does not require a G-protein.
FEBS letters 1988;229(1):54-8.
1988: Exton J H
Role of phosphoinositides in the regulation of liver function.
Hepatology (Baltimore, Md.) 1988;8(1):152-66.
1988: Blackmore P F; Lynch C J; Uhing R J; Fitzgerald T; Bocckino S B; Exton J H
Role of guanine nucleotide regulatory proteins and inositol phosphates in the hormone induced mobilization of hepatocyte calcium.
Advances in experimental medicine and biology 1988;232():169-82.
1987: Lynch C J; Bocckino S B; Blackmore P F; Exton J H
Calcium-mobilizing hormones and phorbol myristate acetate mediate heterologous desensitization of the hormone-sensitive hepatic Na+/K+ pump.
The Biochemical journal 1987;248(3):807-13.
1987: Bocckino S B; Wilson P B; Exton J H
Ca2+-mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation.
FEBS letters 1987;225(1-2):201-4.
1987: Exton J H
Calcium signalling in cells--molecular mechanisms.
Kidney international. Supplement 1987;23():S68-81.
1987: Taylor S J; Exton J H
Guanine-nucleotide and hormone regulation of polyphosphoinositide phospholipase C activity of rat liver plasma membranes. Bivalent-cation and phospholipid requirements.
The Biochemical journal 1987;248(3):791-9.
1987: Bocckino S B; Blackmore P F; Wilson P B; Exton J H
Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism.
The Journal of biological chemistry 1987;262(31):15309-15.
1986: Lynch C J; Wilson P B; Blackmore P F; Exton J H
The hormone-sensitive hepatic Na+-pump. Evidence for regulation by diacylglycerol and tumor promoters.
The Journal of biological chemistry 1986;261(31):14551-6.
1986: Stewart S J; Prpic V; Powers F S; Bocckino S B; Isaacks R E; Exton J H
Perturbation of the human T-cell antigen receptor-T3 complex leads to the production of inositol tetrakisphosphate: evidence for conversion from inositol trisphosphate.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(16):6098-102.
1985: Charest R; Blackmore P F; Exton J H
Characterization of responses of isolated rat hepatocytes to ATP and ADP.
The Journal of biological chemistry 1985;260(29):15789-94.
1985: Lynch C J; Blackmore P F; Charest R; Exton J H
The relationships between receptor binding capacity for norepinephrine, angiotensin II, and vasopressin and release of inositol trisphosphate, Ca2+ mobilization, and phosphorylase activation in rat liver.
Molecular pharmacology 1985;28(2):93-9.
1985: Charest R; Prpic V; Exton J H; Blackmore P F
Stimulation of inositol trisphosphate formation in hepatocytes by vasopressin, adrenaline and angiotensin II and its relationship to changes in cytosolic free Ca2+.
The Biochemical journal 1985;227(1):79-90.
1985: Lynch C J; Charest R; Bocckino S B; Exton J H; Blackmore P F
Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate.
The Journal of biological chemistry 1985;260(5):2844-51.
1985: Lynch C J; Charest R; Blackmore P F; Exton J H
Studies on the hepatic alpha 1-adrenergic receptor. Modulation of guanine nucleotide effects by calcium, temperature, and age.
The Journal of biological chemistry 1985;260(3):1593-600.
1984: Morgan N G; Charest R; Blackmore P F; Exton J H
Potentiation of alpha 1-adrenergic responses in rat liver by a cAMP-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(13):4208-12.
1983: Blackmore P F; Hughes B P; Charest R; Shuman E A; Exton J H
Time course of alpha1-adrenergic and vasopressin actions on phosphorylase activation, calcium efflux, pyridine nucleotide reduction, and respiration in hepatocytes.
The Journal of biological chemistry 1983;258(17):10488-94.
1983: Charest R; Blackmore P F; Berthon B; Exton J H
Changes in free cytosolic Ca2+ in hepatocytes following alpha 1-adrenergic stimulation. Studies on Quin-2-loaded hepatocytes.
The Journal of biological chemistry 1983;258(14):8769-73.
1982: Morgan N G; Shuman E A; Exton J H; Blackmore P F
Stimulation of hepatic glycogenolysis by alpha 1- and beta 2-adrenergic agonists. Evidence against short term agonist-induced desensitization of the responses.
The Journal of biological chemistry 1982;257(23):13907-10.
1982: Blackmore P F; Hughes B P; Shuman E A; Exton J H
alpha-Adrenergic activation of phosphorylase in liver cells involves mobilization of intracellular calcium without influx of extracellular calcium.
The Journal of biological chemistry 1982;257(1):190-7.

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