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Frédéric Fabis

Research Profile

Genes & Molecular Sequences

Molecular Structure

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Publications

TOP 3
Claude Szalata; Jan Szymoniak; Philippe Bertus; Sabrina Butt-Gueulle; Frédéric Fabis; Stéphane Gérard; Sylvain Rault; Janos Sapi
Cyclopropyl-tryptamine analogues: synthesis and biological evaluation as 5-HT(6) receptor ligands.
Emmanuelle Dubost; Fabienne Dulin; Noé Dumas; Céline Ballandonne; Sabrina Butt-Gueulle; Daniel-Henri Caignard; Thomas Cailly; Yves Charnay; Christine Fossey; Rosa Magnelli; Philippe Millet; Sylvain Rault; Jana Sopkova de-Oliveira Santos; Frédéric Fabis
Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.
Florent Péron; Christine Fossey; Thomas Cailly; Frédéric Fabis
N-tosylcarboxamide as a transformable directing group for Pd-catalyzed C-H ortho-arylation.

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2013: Claude Szalata; Jan Szymoniak; Philippe Bertus; Sabrina Butt-Gueulle; Frédéric Fabis; Stéphane Gérard; Sylvain Rault; Janos Sapi
Cyclopropyl-tryptamine analogues: synthesis and biological evaluation as 5-HT(6) receptor ligands.
ChemMedChem 2013;8(1):70-3.
2012: Emmanuelle Dubost; Fabienne Dulin; Noé Dumas; Céline Ballandonne; Sabrina Butt-Gueulle; Daniel-Henri Caignard; Thomas Cailly; Yves Charnay; Christine Fossey; Rosa Magnelli; Philippe Millet; Sylvain Rault; Jana Sopkova de-Oliveira Santos; Frédéric Fabis
Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.
Journal of medicinal chemistry 2012;55(22):9693-707.
2012: Florent Péron; Christine Fossey; Thomas Cailly; Frédéric Fabis
N-tosylcarboxamide as a transformable directing group for Pd-catalyzed C-H ortho-arylation.
Organic letters 2012;14(7):1827-9.
2011: Emmanuelle Dubost; Christine Fossey; Sylvain Rault; Thomas Cailly; Frédéric Fabis
Selective ortho-bromination of substituted benzaldoximes using Pd-catalyzed C-H activation: application to the synthesis of substituted 2-bromobenzaldehydes.
The Journal of organic chemistry 2011;76(15):6414-20.
2010: Thomas Cailly; Noé Dumas; Philippe Millet; Stéphane Lemaître; Frédéric Fabis; Yves Charnay; Sylvain Rault
Synthesis and characterization of a iodine-125-labeled pyrrolo[1,2-a]thieno[3,2-e]pyrazine and evaluation as a potential 5-HT4R SPECT tracer.
European journal of medicinal chemistry 2010;45(11):5465-7.
2010: Jana Sopkova-de Oliveira Santos; Aurélien Lesnard; Jean-Hugues Agondanou; Nathalie Dupont; Anne-Marie Godard; Silvia Stiebing; christophe rochais; Frédéric Fabis; Patrick Dallemagne; Ronan Bureau; Sylvain Rault
Virtual screening discovery of new acetylcholinesterase inhibitors issued from CERMN chemical library.
Journal of chemical information and modeling 2010;50(3):422-8.
2007: Magalie Paillet-Loilier; Frédéric Fabis; Alban Lepailleur; Ronan Bureau; Sabrina Butt-Gueulle; François Dauphin; Aurélien Lesnard; Catherine Delarue; Hubert Vaudry; Sylvain Rault
Novel aminoethylbiphenyls as 5-HT7 receptor ligands.
Bioorganic & medicinal chemistry letters 2007;17(11):3018-22.
2006: Marion Raoul; Dominique Patigny; Frédéric Fabis; François Dauphin; Sylvain Rault; Janos Sapi; Jean-Yves Laronze
N-arylsulfonyl-2-vinyltryptamines as new 5-HT6 serotonin receptor ligands.
Journal of enzyme inhibition and medicinal chemistry 2006;21(3):251-60.
2005: Ziad Omran; Thomas Cailly; Elodie Lescot; Jana Sopkova-de Oliveira Santos; Jean-Hugues Agondanou; vincent lisowski; Frédéric Fabis; Anne-Marie Godard; Silvia Stiebing; Guillaume Le Flem; Michel Boulouard; François Dauphin; Patrick Dallemagne; Sylvain Rault
Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil.
European journal of medicinal chemistry 2005;40(12):1222-45.
2005: Magalie Paillet-Loilier; Frédéric Fabis; Alban Lepailleur; Ronan Bureau; Sabrina Butt-Gueulle; François Dauphin; Catherine Delarue; Hubert Vaudry; Sylvain Rault
Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.
Bioorganic & medicinal chemistry letters 2005;15(16):3753-7.
2005: Alban Lepailleur; Ronan Bureau; Magalie Paillet-Loilier; Frédéric Fabis; Nicolas Saettel; Stéphane Lemaître; François Dauphin; Aurélien Lesnard; Jean-Charles Lancelot; Sylvain Rault
Molecular modeling studies focused on 5-HT7 versus 5-HT1A selectivity. Discovery of novel phenylpyrrole derivatives with high affinity for 5-HT7 receptors.
Journal of chemical information and modeling 2005;45(4):1075-81.
2005: François-Xavier Le Foulon; Emmanuelle Braud; Frédéric Fabis; Jean-Charles Lancelot; Sylvain Rault
Solution-phase parallel synthesis of a 1140-member ureidothiophene carboxylic acid library.
Journal of combinatorial chemistry 2005;7(2):253-7.
2004: Jacques Renault; Aurelie Bernard; Solenn Brajeul; Pierre Verhaeghe; Sabrina Butt; Frédéric Fabis; François Dauphin; Philippe Uriac; Sylvain Rault
Pharmacomodulation of a sulfamide 5-HT6 receptor ligand.
Journal of enzyme inhibition and medicinal chemistry 2004;19(6):577-83.
2002: vincent lisowski; Frédéric Fabis; Alain Pierré; Daniel-Henri Caignard; Pierre Renard; Sylvain Rault
Synthesis of new aromatic pyrrolo[2,1-c] [1,4]benzodiazepines and pyrrolo[1,2-a]thieno[3,2-e] [1,4]diazepines as anti-tumoral agents.
Journal of enzyme inhibition and medicinal chemistry 2002;17(6):403-7.
2001: Jacques Renault; Frédéric Fabis; François Dauphin; M Lebranchu; Myriam Le Roch; Sabrina Butt; Philippe Uriac; Sylvain Rault
Solid phase synthesis of sulphonamides: novel ligands of 5-HT6 receptors.
The Journal of pharmacy and pharmacology 2001;53(7):969-72.