Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
James Fagin
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Disorders
Living Beings
Chemicals & Drugs
Physiology
Anatomy
Genes & Molecular Sequences
Sign-in to see full Profile
Network (preview)
26
Knauf, Jeffrey
24
Nikiforov, Yuri
15
Forrester, James
12
Clemens, Thomas
11
Nikiforova, Marina
10
Sharifi, Behrooz
9
Pirola, Carlos
7
Mitsutake, Norisato
7
Gutman, RA
6
Elisei, R
6
Medvedovic, Mario
6
Puxeddu, Efisio
6
Smith, Eric
5
Santoro, Massimo
5
Ouyang, Bin
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of James Fagin (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Tuttle R Michael; Fagin James A
Can risk-adapted treatment recommendations replace the 'one size fits all' approach for early-stage thyroid cancer patients?
Oncology (Williston Park, N.Y.) 2009;23(7):592, 600, 603.
-
2009: Ricarte-Filho Julio C; Ryder Mabel; Chitale Dhananjay A; Rivera Michael; Heguy Adriana; Ladanyi Marc; Janakiraman Manickam; Solit David; Knauf Jeffrey A; Tuttle R Michael; Ghossein Ronald A; Fagin James A
Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.
Cancer research 2009;69(11):4885-93.
-
2009: Veeriah Selvaraju; Brennan Cameron; Meng Shasha; Singh Bhuvanesh; Fagin James A; Solit David B; Paty Philip B; Rohle Dan; Vivanco Igor; Chmielecki Juliann; Pao William; Ladanyi Marc; Gerald William L; Liau Linda; Cloughesy Timothy C; Mischel Paul S; Sander Chris; Taylor Barry; Schultz Nikolaus; Major John; Heguy Adriana; Fang Fang; Mellinghoff Ingo K; Chan Timothy A
The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(23):9435-40.
-
2009: Nikiforov Yuri E; Steward David L; Robinson-Smith Toni M; Haugen Bryan R; Klopper Joshua P; Zhu Zhaowen; Fagin James A; Falciglia Mercedes; Weber Katherine; Nikiforova Marina N
Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules.
The Journal of clinical endocrinology and metabolism 2009;94(6):2092-8.
-
2009: Chen Xu; Mitsutake Norisato; LaPerle Krista; Akeno Nagako; Zanzonico Pat; Longo Valerie A; Mitsutake Shin; Kimura Edna T; Geiger Hartmut; Santos Eugenio; Wendel Hans G; Franco Aime; Knauf Jeffrey A; Fagin James A
Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(19):7979-84.
-
2009: Knauf Jeffrey A; Fagin James A
Role of MAPK pathway oncoproteins in thyroid cancer pathogenesis and as drug targets.
Current opinion in cell biology 2009;21(2):296-303.
-
2008: Fagin James A; Mitsiades Nicholas
Molecular pathology of thyroid cancer: diagnostic and clinical implications.
Best practice & research. Clinical endocrinology & metabolism 2008;22(6):955-69.
-
2008: Ryder Mabel; Ghossein Ronald A; Ricarte-Filho Julio C M; Knauf Jeffrey A; Fagin James A
Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer.
Endocrine-related cancer 2008;15(4):1069-74.
-
2008: Schweppe Rebecca E; Klopper Joshua P; Korch Christopher; Pugazhenthi Umarani; Benezra Miriam; Knauf Jeffrey A; Fagin James A; Marlow Laura A; Copland John A; Smallridge Robert C; Haugen Bryan R
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
The Journal of clinical endocrinology and metabolism 2008;93(11):4331-41.
-
2008: Pfister David G; Fagin James A
Refractory thyroid cancer: a paradigm shift in treatment is not far off.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(29):4701-4.
-
2008: Croyle Michelle; Akeno Nagako; Knauf Jeffrey A; Fabbro Doriano; Chen Xu; Baumgartner Jacqueline E; Lane Heidi A; Fagin James A
RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR.
Cancer research 2008;68(11):4183-91.
-
2008: Leboeuf Rebecca; Baumgartner Jacqueline E; Benezra Miriam; Malaguarnera Roberta; Solit David; Pratilas Christine A; Rosen Neal; Knauf Jeffrey A; Fagin James A
BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines.
The Journal of clinical endocrinology and metabolism 2008;93(6):2194-201.
-
2007: Simmons J G; Ling Y; Wilkins H; Fuller C R; D'Ercole A J; Fagin James; Lund P K
Cell-specific effects of insulin receptor substrate-1 deficiency on normal and IGF-I-mediated colon growth.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(5):G995-1003.
-
2007: Fagin James A; Ward Laura S; Kimura Edna T
[Thyroid cancer: past, present and future.]
Arquivos brasileiros de endocrinologia e metabologia 2007;51(5):641-2.
-
2007: Akeno-Stuart Nagako; Croyle Michelle; Knauf Jeffrey A; Malaguarnera Roberta; Vitagliano Donata; Santoro Massimo; Stephan Christine; Grosios Konstantina; Wartmann Markus; Cozens Robert; Caravatti Giorgio; Fabbro Doriano; Lane Heidi A; Fagin James A
The RET kinase inhibitor NVP-AST487 blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells.
Cancer research 2007;67(14):6956-64.
-
2007: Ryder Mabel; Nikiforov Yuri E; Fagin James A
Follicular variant papillary thyroid carcinoma arising within an ovarian teratoma.
Thyroid : official journal of the American Thyroid Association 2007;17(2):179-80.
-
2007: Fagin James A
The Jeremiah Metzger Lecture: intelligent design of cancer therapy: trials and tribulations.
Transactions of the American Clinical and Climatological Association 2007;118():253-61.
-
2006: Mesa Cleo; Mirza Mana; Mitsutake Norisato; Sartor Maureen; Medvedovic Mario; Tomlinson Craig; Knauf Jeffrey A; Weber Georg F; Fagin James A
Conditional activation of RET/PTC3 and BRAFV600E in thyroid cells is associated with gene expression profiles that predict a preferential role of BRAF in extracellular matrix remodeling.
Cancer research 2006;66(13):6521-9.
-
2006: Groussin Lionel; Fagin James A
Significance of BRAF mutations in papillary thyroid carcinoma: prognostic and therapeutic implications.
Nature clinical practice. Endocrinology & metabolism 2006;2(4):180-1.
-
2006: Ouyang Bin; Knauf Jeffrey A; Smith Eric P; Zhang Lei; Ramsey Tim; Yusuff Naeem; Batt David; Fagin James A
Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1785-93.
-
2006: Knauf Jeffrey A; Ouyang Bin; Knudsen Erik S; Fukasawa Kenji; Babcock George; Fagin James A
Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints.
The Journal of biological chemistry 2006;281(7):3800-9.
-
2006: Mitsutake Norisato; Miyagishi Makoto; Mitsutake Shin; Akeno Nagako; Mesa Cleo; Knauf Jeffrey A; Zhang Lei; Taira Kazunari; Fagin James A
BRAF mediates RET/PTC-induced mitogen-activated protein kinase activation in thyroid cells: functional support for requirement of the RET/PTC-RAS-BRAF pathway in papillary thyroid carcinogenesis.
Endocrinology 2006;147(2):1014-9.
-
2005: Puxeddu E; Knauf J A; Sartor M A; Mitsutake N; Smith E P; Medvedovic M; Tomlinson C R; Moretti S; Fagin J A
RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in regulation of the immune response.
Endocrine-related cancer 2005;12(2):319-34.
-
2005: Knauf Jeffrey A; Ma Xiaolan; Smith Eric P; Zhang Lei; Mitsutake Norisato; Liao Xiao-Hui; Refetoff Samuel; Nikiforov Yuri E; Fagin James A
Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.
Cancer research 2005;65(10):4238-45.
-
2005: Ciampi Raffaele; Knauf Jeffrey A; Rabes Hartmut M; Fagin James A; Nikiforov Yuri E
BRAF kinase activation via chromosomal rearrangement in radiation-induced and sporadic thyroid cancer.
Cell cycle (Georgetown, Tex.) 2005;4(4):547-8.
-
2005: Mitsutake Norisato; Knauf Jeffrey A; Mitsutake Shin; Mesa Cleo; Zhang Lei; Fagin James A
Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells.
Cancer research 2005;65(6):2465-73.
-
2005: Puxeddu Efisio; Zhao Guisheng; Stringer James R; Medvedovic Mario; Moretti Sonia; Fagin James A
Characterization of novel non-clonal intrachromosomal rearrangements between the H4 and PTEN genes (H4/PTEN) in human thyroid cell lines and papillary thyroid cancer specimens.
Mutation research 2005;570(1):17-32.
-
2005: Ciampi Raffaele; Knauf Jeffrey A; Kerler Roswitha; Gandhi Manoj; Zhu Zhaowen; Nikiforova Marina N; Rabes Hartmut M; Fagin James A; Nikiforov Yuri E
Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer.
The Journal of clinical investigation 2005;115(1):94-101.
-
2005: Sanz S; Pucilowska J B; Liu S; Rodríguez-Ortigosa C M; Lund P K; Brenner D A; Fuller C R; Simmons J G; Pardo A; Martínez-Chantar M-L; Fagin J A; Prieto J
Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.
Gut 2005;54(1):134-41.
-
2005: Fagin James A
Genetics of papillary thyroid cancer initiation: implications for therapy.
Transactions of the American Clinical and Climatological Association 2005;116():259-69; discussion 269-71.
-
2004: Fagin J A
How thyroid tumors start and why it matters: kinase mutants as targets for solid cancer pharmacotherapy.
The Journal of endocrinology 2004;183(2):249-56.
-
2004: Salvatore Giuliana; Giannini Riccardo; Faviana Pinuccia; Caleo Alessia; Migliaccio Ilenia; Fagin James A; Nikiforov Yuri E; Troncone Giancarlo; Palombini Lucio; Basolo Fulvio; Santoro Massimo
Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2004;89(10):5175-80.
-
2004: Fagin James A
Challenging dogma in thyroid cancer molecular genetics--role of RET/PTC and BRAF in tumor initiation.
The Journal of clinical endocrinology and metabolism 2004;89(9):4264-6.
-
2004: Knott Andrew W; Juno Russell J; Jarboe Marcus D; Profitt Sherri A; Erwin Christopher R; Smith Eric P; Fagin James A; Warner Brad W
Smooth muscle overexpression of IGF-I induces a novel adaptive response to small bowel resection.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(3):G562-70.
-
2004: Nikiforova Marina N; Ciampi Raffaele; Salvatore Giuliana; Santoro Massimo; Gandhi Manoj; Knauf Jeffrey A; Thomas Gerry A; Jeremiah Stephen; Bogdanova Tatyana I; Tronko Mykola D; Fagin James A; Nikiforov Yuri E
Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.
Cancer letters 2004;209(1):1-6.
-
2004: Kimura Edna T; Vanvooren Vanessa; van Sande Jacqueline; Nikiforov Yuri E; Fagin James A
Autonomously functioning thyroid nodules are not associated with BRAF mutations.
Clinical endocrinology 2004;60(3):394-6.
-
2003: Puxeddu Efisio; Mitsutake Norisato; Knauf Jeffrey A; Moretti Sonia; Kim Hei W; Seta Karen A; Brockman Diane; Myatt Leslie; Millhorn David E; Fagin James A
Microsomal prostaglandin E2 synthase-1 is induced by conditional expression of RET/PTC in thyroid PCCL3 cells through the activation of the MEK-ERK pathway.
The Journal of biological chemistry 2003;278(52):52131-8.
-
2003: Nikiforova Marina N; Kimura Edna T; Gandhi Manoj; Biddinger Paul W; Knauf Jeffrey A; Basolo Fulvio; Zhu Zhaowen; Giannini Riccardo; Salvatore Giuliana; Fusco Alfredo; Santoro Massimo; Fagin James A; Nikiforov Yuri E
BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas.
The Journal of clinical endocrinology and metabolism 2003;88(11):5399-404.
-
2003: Knauf Jeffrey A; Ouyang Bin; Croyle Mickey; Kimura Edna; Fagin James A
Acute expression of RET/PTC induces isozyme-specific activation and subsequent downregulation of PKCepsilon in PCCL3 thyroid cells.
Oncogene 2003;22(44):6830-8.
-
2003: Knauf Jeffrey A; Kuroda Hiroaki; Basu Saswata; Fagin James A
RET/PTC-induced dedifferentiation of thyroid cells is mediated through Y1062 signaling through SHC-RAS-MAP kinase.
Oncogene 2003;22(28):4406-12.
-
2003: Wang Jianwei; Knauf Jeffrey A; Basu Saswata; Puxeddu Efisio; Kuroda Hiroaki; Santoro Massimo; Fusco Alfredo; Fagin James A
Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels.
Molecular endocrinology (Baltimore, Md.) 2003;17(7):1425-36.
-
2003: Kimura Edna T; Nikiforova Marina N; Zhu Zhaowen; Knauf Jeffrey A; Nikiforov Yuri E; Fagin James A
High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.
Cancer research 2003;63(7):1454-7.
-
2003: Castellone Maria Domenica; Cirafici Anna Maria; De Vita Gabriella; De Falco Valentina; Malorni Luca; Tallini Giovanni; Fagin James A; Fusco Alfredo; Melillo Rosa Marina; Santoro Massimo
Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes.
Oncogene 2003;22(2):246-55.
-
2002: Williams Kristen L; Fuller C Randall; Fagin James; Lund P Kay
Mesenchymal IGF-I overexpression: paracrine effects in the intestine, distinct from endocrine actions.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(4):G875-85.
-
2002: Fagin James A
Perspective: lessons learned from molecular genetic studies of thyroid cancer--insights into pathogenesis and tumor-specific therapeutic targets.
Endocrinology 2002;143(6):2025-8.
-
2002: Zhang Mingyu; Smith Eric P; Kuroda Hiroaki; Banach Walter; Chernausek Steven D; Fagin James A
Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy.
The Journal of biological chemistry 2002;277(24):21285-90.
-
2002: Knauf Jeffrey A; Ward Laura S; Nikiforov Yuri E; Nikiforova Marina; Puxeddu Efisio; Medvedovic Mario; Liron Tamar; Mochly-Rosen Daria; Fagin James A
Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon.
The Journal of clinical endocrinology and metabolism 2002;87(5):2150-9.
-
2002: Fagin James A
Minireview: branded from the start-distinct oncogenic initiating events may determine tumor fate in the thyroid.
Molecular endocrinology (Baltimore, Md.) 2002;16(5):903-11.
-
2002: Ouyang Bin; Knauf Jeffrey A; Ain Kenneth; Nacev Benjamin; Fagin James A
Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1.
Clinical endocrinology 2002;56(3):341-50.
-
2001: Smith E P; Kamyar A; Niu W; Wang J; Cercek B; Chernausek S D; Fagin J A
IGF-binding protein-4 expression and IGF-binding protein-4 protease activity are regulated coordinately in smooth muscle during postnatal development and after vascular injury.
Endocrinology 2001;142(10):4420-7.
-
2001: Zhu B; Zhao G; Witte D P; Hui D Y; Fagin J A
Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury.
Endocrinology 2001;142(8):3598-606.
-
2001: Puxeddu E; Fagin J A
Genetic markers in thyroid neoplasia.
Endocrinology and metabolism clinics of North America 2001;30(2):493-513, x.
-
2001: Zhao G; Sutliff R L; Weber C S; Wang J; Lorenz J; Paul R J; Fagin J A
Smooth muscle-targeted overexpression of insulin-like growth factor I results in enhanced vascular contractility.
Endocrinology 2001;142(2):623-32.
-
2001: Fagin J A
[Thyroid cancer: epidemiology and predisposing mechanisms due to ionizing radiation]
Medicina 2001;61(5 Pt 2):655-7.
-
2001: Fagin J A
Mouse genetic models to explore the function of IGF-I in smooth muscle.
Medicina 2001;61(5 Pt 2):653-4.
-
2001: Mochly-Rosen D; Fagin J A; Knauf J A; Nikiforov Y; Liron T; Schechtman D
Spontaneous occurrence of an inhibitor of protein kinase C localization in a thyroid cancer cell line: role in thyroid tumorigenesis.
Advances in enzyme regulation 2001;41():87-97.
-
2000: Shirokawa J M; Elisei R; Knauf J A; Hara T; Wang J; Saavedra H I; Fagin J A
Conditional apoptosis induced by oncogenic ras in thyroid cells.
Molecular endocrinology (Baltimore, Md.) 2000;14(11):1725-38.
-
2000: Martelli M L; Miano M G; Battaglia C; Trapasso F; Stella A; Iuliano R; Visconti R; Fagin J A; Santoro M; Fusco A
The highly malignant phenotype of anaplastic thyroid carcinoma cell lines is recessive.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(4):515-21.
-
2000: Nikiforova M N; Stringer J R; Blough R; Medvedovic M; Fagin J A; Nikiforov Y E
Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells.
Science (New York, N.Y.) 2000;290(5489):138-41.
-
2000: Saavedra H I; Knauf J A; Shirokawa J M; Wang J; Ouyang B; Elisei R; Stambrook P J; Fagin J A
The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.
Oncogene 2000;19(34):3948-54.
-
2000: Stuart W D; Maeda S; Khera P; Fagin J A; Clemens T L
Parathyroid hormone-related protein induces G1 phase growth arrest of vascular smooth muscle cells.
American journal of physiology. Endocrinology and metabolism 2000;279(1):E60-7.
-
2000: Zhao G; Monier-Faugere M C; Langub M C; Geng Z; Nakayama T; Pike J W; Chernausek S D; Rosen C J; Donahue L R; Malluche H H; Fagin J A; Clemens T L
Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation.
Endocrinology 2000;141(7):2674-82.
-
1999: Nikiforov Y E; Koshoffer A; Nikiforova M; Stringer J; Fagin J A
Chromosomal breakpoint positions suggest a direct role for radiation in inducing illegitimate recombination between the ELE1 and RET genes in radiation-induced thyroid carcinomas.
Oncogene 1999;18(46):6330-4.
-
1999: Knauf J A; Elisei R; Mochly-Rosen D; Liron T; Chen X N; Gonsky R; Korenberg J R; Fagin J A
Involvement of protein kinase Cepsilon (PKCepsilon) in thyroid cell death. A truncated chimeric PKCepsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis.
The Journal of biological chemistry 1999;274(33):23414-25.
-
1999: Nikiforova M N; Nikiforov Y E; Biddinger P; Gnepp D R; Grosembacher L A; Wajchenberg B L; Fagin J A; Cohen R M
Frequent loss of heterozygosity at chromosome 3p14.2-3p21 in human pancreatic islet cell tumours.
Clinical endocrinology 1999;51(1):27-33.
-
1999: Qian J; Lorenz J N; Maeda S; Sutliff R L; Weber C; Nakayama T; Colbert M C; Paul R J; Fagin J A; Clemens T L
Reduced blood pressure and increased sensitivity of the vasculature to parathyroid hormone-related protein (PTHrP) in transgenic mice overexpressing the PTH/PTHrP receptor in vascular smooth muscle.
Endocrinology 1999;140(4):1826-33.
-
1999: Maeda S; Sutliff R L; Qian J; Lorenz J N; Wang J; Tang H; Nakayama T; Weber C; Witte D; Strauch A R; Paul R J; Fagin J A; Clemens T L
Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility.
Endocrinology 1999;140(4):1815-25.
-
1998: Fainstein Day P; Fagin J A; Vaglio R M; Litwak L E; Picasso M F; Gutman R A
Growth hormone-insulin-like growth factor-I axis in adult insulin-dependent diabetic patients: evidence for central hypersensitivity to growth hormone-releasing hormone and peripheral resistance to growth hormone.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1998;30(12):737-42.
-
1998: Elisei R; Shiohara M; Koeffler H P; Fagin J A
Genetic and epigenetic alterations of the cyclin-dependent kinase inhibitors p15INK4b and p16INK4a in human thyroid carcinoma cell lines and primary thyroid carcinomas.
Cancer 1998;83(10):2185-93.
-
1998: Garcia S I; Clemens T L; Fagin J A; Finkielman S; Pirola C J
Parathyroid hormone-related protein expression in vascular smooth muscle of spontaneously hypertensive rats: evidence for lack of response to angiotensin II.
Journal of hypertension 1998;16(10):1467-74.
-
1998: Nikiforov Y E; Nikiforova M; Fagin J A
Prevalence of minisatellite and microsatellite instability in radiation-induced post-Chernobyl pediatric thyroid carcinomas.
Oncogene 1998;17(15):1983-8.
-
1998: Chen X; Knauf J A; Gonsky R; Wang M; Lai E H; Chissoe S; Fagin J A; Korenberg J R
From amplification to gene in thyroid cancer: a high-resolution mapped bacterial-artificial-chromosome resource for cancer chromosome aberrations guides gene discovery after comparative genome hybridization.
American journal of human genetics 1998;63(2):625-37.
-
1998: Motomura T; Nikiforov Y E; Namba H; Ashizawa K; Nagataki S; Yamashita S; Fagin J A
ret rearrangements in Japanese pediatric and adult papillary thyroid cancers.
Thyroid : official journal of the American Thyroid Association 1998;8(6):485-9.
-
1998: Wang J; Niu W; Witte D P; Chernausek S D; Nikiforov Y E; Clemens T L; Sharifi B; Strauch A R; Fagin J A
Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia.
Endocrinology 1998;139(5):2605-14.
-
1998: Naito S; Shimizu S; Maeda S; Wang J; Paul R; Fagin J A
Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells.
The American journal of physiology 1998;274(2 Pt 1):C472-80.
-
1998: Ward L S; Brenta G; Medvedovic M; Fagin J A
Studies of allelic loss in thyroid tumors reveal major differences in chromosomal instability between papillary and follicular carcinomas.
The Journal of clinical endocrinology and metabolism 1998;83(2):525-30.
-
1997: LaFleur D W; Chiang J; Fagin J A; Schwartz S M; Shah P K; Wallner K; Forrester J S; Sharifi B G
Aortic smooth muscle cells interact with tenascin-C through its fibrinogen-like domain.
The Journal of biological chemistry 1997;272(52):32798-803.
-
1997: Gonsky R; Knauf J A; Elisei R; Wang J W; Su S; Fagin J A
Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: use of a targeted differential RNA display method to select for mRNA subsets.
Nucleic acids research 1997;25(19):3823-31.
-
1997: Wang J; Niu W; Nikiforov Y; Naito S; Chernausek S; Witte D; LeRoith D; Strauch A; Fagin J A
Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice.
The Journal of clinical investigation 1997;100(6):1425-39.
-
1997: Nikiforov Y E; Rowland J M; Bove K E; Monforte-Munoz H; Fagin J A
Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.
Cancer research 1997;57(9):1690-4.
-
1997: Yumi K; Fagin J A; Yamashita M; Fishbein M C; Shah P K; Kaul S; Niu W; Nilsson J; Cercek B
Direct effects of somatostatin analog octreotide on insulin-like growth factor-I in the arterial wall.
Laboratory investigation; a journal of technical methods and pathology 1997;76(3):329-38.
-
1997: Fagin J A
Familial nonmedullary thyroid carcinoma--the case for genetic susceptibility.
The Journal of clinical endocrinology and metabolism 1997;82(2):342-4.
-
1997: Nikiforov Y E; Fagin J A
Risk factors for thyroid cancer.
Trends in endocrinology and metabolism: TEM 1997;8(1):20-5.
-
1996: Nakayama T; Ito M; Ohtsuru A; Naito S; Nakashima M; Fagin J A; Yamashita S; Sekine I
Expression of the Ets-1 proto-oncogene in human gastric carcinoma: correlation with tumor invasion.
The American journal of pathology 1996;149(6):1931-9.
-
1996: Spambalg D; Sharifi N; Elisei R; Gross J L; Medeiros-Neto G; Fagin J A
Structural studies of the thyrotropin receptor and Gs alpha in human thyroid cancers: low prevalence of mutations predicts infrequent involvement in malignant transformation.
The Journal of clinical endocrinology and metabolism 1996;81(11):3898-901.
-
1996: Nikiforov Y E; Nikiforova M N; Gnepp D R; Fagin J A
Prevalence of mutations of ras and p53 in benign and malignant thyroid tumors from children exposed to radiation after the Chernobyl nuclear accident.
Oncogene 1996;13(4):687-93.
-
1996: Maeda S; Wu S; Jüppner H; Green J; Aragay A M; Fagin J A; Clemens T L
Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells.
Endocrinology 1996;137(8):3154-62.
-
1996: Hultgårdh-Nilsson A; Cercek B; Wang J W; Naito S; Lövdahl C; Sharifi B; Forrester J S; Fagin J A
Regulated expression of the ets-1 transcription factor in vascular smooth muscle cells in vivo and in vitro.
Circulation research 1996;78(4):589-95.
-
1996: Fagin J A; Tang S H; Zeki K; Di Lauro R; Fusco A; Gonsky R
Reexpression of thyroid peroxidase in a derivative of an undifferentiated thyroid carcinoma cell line by introduction of wild-type p53.
Cancer research 1996;56(4):765-71.
-
1996: Cerutti J; Trapasso F; Battaglia C; Zhang L; Martelli M L; Visconti R; Berlingieri M T; Fagin J A; Santoro M; Fusco A
Block of c-myc expression by antisense oligonucleotides inhibits proliferation of human thyroid carcinoma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(1):119-26.
-
1996: Nikiforov Y; Gnepp D R; Fagin J A
Thyroid lesions in children and adolescents after the Chernobyl disaster: implications for the study of radiation tumorigenesis.
The Journal of clinical endocrinology and metabolism 1996;81(1):9-14.
-
1996: Melmed S; Yamashita S; Yamasaki H; Fagin J; Namba H; Yamamoto H; Weber M; Morita S; Webster J; Prager D
IGF-I receptor signalling: lessons from the somatotroph.
Recent progress in hormone research 1996;51():189-215; discussion 215-6.
-
1995: Battista S; Martelli M L; Fedele M; Chiappetta G; Trapasso F; De Vita G; Battaglia C; Santoro M; Viglietto G; Fagin J A
A mutated p53 gene alters thyroid cell differentiation.
Oncogene 1995;11(10):2029-37.
-
1995: Nikiforov Y E; Heffess C S; Korzenko A V; Fagin J A; Gnepp D R
Characteristics of follicular tumors and nonneoplastic thyroid lesions in children and adolescents exposed to radiation as a result of the Chernobyl disaster.
Cancer 1995;76(5):900-9.
-
1995: Okano K; Pirola C J; Wang H M; Forrester J S; Fagin J A; Clemens T L
Involvement of cell cycle and mitogen-activated pathways in induction of parathyroid hormone-related protein gene expression in rat aortic smooth muscle cells.
Endocrinology 1995;136(4):1782-9.
-
1995: Herman-Bonert V; Fagin J A
Molecular pathogenesis of pituitary tumours.
Baillière's clinical endocrinology and metabolism 1995;9(2):203-23.
-
1995: Fagin J A
Tumor suppressor genes in human thyroid neoplasms: p53 mutations are associated undifferentiated thyroid cancers.
Journal of endocrinological investigation 1995;18(2):140-2.
-
1994: Zeki K; Spambalg D; Sharifi N; Gonsky R; Fagin J A
Mutations of the adenomatous polyposis coli gene in sporadic thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 1994;79(5):1317-21.
-
1994: Bailey W L; LaFleur D W; Forrester J S; Fagin J A; Sharifi B G
Stimulation of rat vascular smooth muscle cell glycosaminoglycan production by angiotensin II.
Atherosclerosis 1994;111(1):55-64.
-
1994: Okano K; Wu S; Huang X; Pirola C J; Juppner H; Abou-Samra A B; Segre G V; Iwasaki K; Fagin J A; Clemens T L
Parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptor and its messenger ribonucleic acid in rat aortic vascular smooth muscle cells and UMR osteoblast-like cells: cell-specific regulation by angiotensin-II and PTHrP.
Endocrinology 1994;135(3):1093-9.
-
1994: LaFleur D W; Fagin J A; Forrester J S; Rubin S A; Sharifi B G
Cloning and characterization of alternatively spliced isoforms of rat tenascin. Platelet-derived growth factor-BB markedly stimulates expression of spliced variants of tenascin mRNA in arterial smooth muscle cells.
The Journal of biological chemistry 1994;269(32):20757-63.
-
1994: Pirola C J; Wang H M; Strgacich M I; Kamyar A; Cercek B; Forrester J S; Clemens T L; Fagin J A
Mechanical stimuli induce vascular parathyroid hormone-related protein gene expression in vivo and in vitro.
Endocrinology 1994;134(5):2230-6.
-
1994: Kamyar A; Pirola C J; Wang H M; Sharifi B; Mohan S; Forrester J S; Fagin J A
Expression and insulin-like growth factor-dependent proteolysis of insulin-like growth factor-binding protein-4 are regulated by cell confluence in vascular smooth muscle cells.
Circulation research 1994;74(4):576-85.
-
1994: Fagin J A
Molecular genetics of human thyroid neoplasms.
Annual review of medicine 1994;45():45-52.
-
1993: Wu S; Pirola C J; Green J; Yamaguchi D T; Okano K; Jueppner H; Forrester J S; Fagin J A; Clemens T L
Effects of N-terminal, midregion, and C-terminal parathyroid hormone-related peptides on adenosine 3',5'-monophosphate and cytoplasmic free calcium in rat aortic smooth muscle cells and UMR-106 osteoblast-like cells.
Endocrinology 1993;133(6):2437-44.
-
1993: Matsuo K; Tang S H; Sharifi B; Rubin S A; Schreck R; Fagin J A
Growth factor production by human thyroid carcinoma cells: abundant expression of a platelet-derived growth factor-B-like protein by a human papillary carcinoma cell line.
The Journal of clinical endocrinology and metabolism 1993;77(4):996-1004.
-
1993: Matsuo K; Tang S H; Zeki K; Gutman R A; Fagin J A
Aberrant deoxyribonucleic acid methylation in human thyroid tumors.
The Journal of clinical endocrinology and metabolism 1993;77(4):991-5.
-
1993: Matsuo K; Friedman E; Gejman P V; Fagin J A
The thyrotropin receptor (TSH-R) is not an oncogene for thyroid tumors: structural studies of the TSH-R and the alpha-subunit of Gs in human thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 1993;76(6):1446-51.
-
1993: Fagin J A; Matsuo K; Karmakar A; Chen D L; Tang S H; Koeffler H P
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas.
The Journal of clinical investigation 1993;91(1):179-84.
-
1993: Pirola C J; Wang H M; Kamyar A; Wu S; Enomoto H; Sharifi B; Forrester J S; Clemens T L; Fagin J A
Angiotensin II regulates parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and post-transcriptional mechanisms.
The Journal of biological chemistry 1993;268(3):1987-94.
-
1992: Fagin J A
Genetic basis of endocrine disease 3: Molecular defects in thyroid gland neoplasia.
The Journal of clinical endocrinology and metabolism 1992;75(6):1398-400.
-
1992: Khorsandi M J; Fagin J A; Giannella-Neto D; Forrester J S; Cercek B
Regulation of insulin-like growth factor-I and its receptor in rat aorta after balloon denudation. Evidence for local bioactivity.
The Journal of clinical investigation 1992;90(5):1926-31.
-
1992: Sharifi B G; LaFleur D W; Pirola C J; Forrester J S; Fagin J A
Angiotensin II regulates tenascin gene expression in vascular smooth muscle cells.
The Journal of biological chemistry 1992;267(33):23910-5.
-
1992: Giannella-Neto D; Kamyar A; Sharifi B; Pirola C J; Kupfer J; Rosenfeld R G; Forrester J S; Fagin J A
Platelet-derived growth factor isoforms decrease insulin-like growth factor I gene expression in rat vascular smooth muscle cells and selectively stimulate the biosynthesis of insulin-like growth factor binding protein 4.
Circulation research 1992;71(3):646-56.
-
1992: Khorsandi M; Fagin J A; Fishbein M C; Forrester J S; Cercek B
Effects of hypophysectomy on vascular insulin-like growth factor-I gene expression after balloon denudation in rats.
Atherosclerosis 1992;93(1-2):115-22.
-
1991: Matsuo K; Tang S H; Fagin J A
Allelotype of human thyroid tumors: loss of chromosome 11q13 sequences in follicular neoplasms.
Molecular endocrinology (Baltimore, Md.) 1991;5(12):1873-9.
-
1991: Gonsky R; Herman V; Melmed S; Fagin J
Transforming DNA sequences present in human prolactin-secreting pituitary tumors.
Molecular endocrinology (Baltimore, Md.) 1991;5(11):1687-95.
-
1991: Namba H; Ross J L; Goodman D; Fagin J A
Solitary polyclonal autonomous thyroid nodule: a rare cause of childhood hyperthyroidism.
The Journal of clinical endocrinology and metabolism 1991;72(5):1108-12.
-
1991: Forrester J S; Fishbein M; Helfant R; Fagin J
A paradigm for restenosis based on cell biology: clues for the development of new preventive therapies.
Journal of the American College of Cardiology 1991;17(3):758-69.
-
1990: Herman V; Fagin J; Gonsky R; Kovacs K; Melmed S
Clonal origin of pituitary adenomas.
The Journal of clinical endocrinology and metabolism 1990;71(6):1427-33.
-
1990: Namba H; Rubin S A; Fagin J A
Point mutations of ras oncogenes are an early event in thyroid tumorigenesis.
Molecular endocrinology (Baltimore, Md.) 1990;4(10):1474-9.
-
1990: Namba H; Gutman R A; Matsuo K; Alvarez A; Fagin J A
H-ras protooncogene mutations in human thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 1990;71(1):223-9.
-
1990: Namba H; Matsuo K; Fagin J A
Clonal composition of benign and malignant human thyroid tumors.
The Journal of clinical investigation 1990;86(1):120-5.
-
1990: Cercek B; Fishbein M C; Forrester J S; Helfant R H; Fagin J A
Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation.
Circulation research 1990;66(6):1755-60.
-
1989: Fagin J A; Fernandez-Mejia C; Melmed S
Pituitary insulin-like growth factor-I gene expression: regulation by triiodothyronine and growth hormone.
Endocrinology 1989;125(5):2385-91.
-
1989: Fagin J A; Roberts C T; LeRoith D; Brown A T
Coordinate decrease of tissue insulinlike growth factor I posttranscriptional alternative mRNA transcripts in diabetes mellitus.
Diabetes 1989;38(4):428-34.
-
1988: Fagin J A; Brown A; Melmed S
Regulation of pituitary insulin-like growth factor-I messenger ribonucleic acid levels in rats harboring somatomammotropic tumors: implications for growth hormone autoregulation.
Endocrinology 1988;122(5):2204-10.
-
1987: Fagin J A; Ikejiri K; Levin S R
Insulinotropic effects of vanadate.
Diabetes 1987;36(12):1448-52.
-
1987: Fagin J A; Pixley S; Slanina S; Ong J; Melmed S
Insulin-like growth factor I gene expression in GH3 rat pituitary cells: messenger ribonucleic acid content, immunocytochemistry, and secretion.
Endocrinology 1987;120(5):2037-43.
-
1987: Melmed S; Fagin J A
Acromegaly update--etiology, diagnosis and management.
The Western journal of medicine 1987;146(3):328-36.
-
1987: Fagin J A; Melmed S
Relative increase in insulin-like growth factor I messenger ribonucleic acid levels in compensatory renal hypertrophy.
Endocrinology 1987;120(2):718-24.
-
1986: Yamashita S; Ong J; Fagin J A; Melmed S
Expression of the myc cellular proto-oncogene in human thyroid tissue.
The Journal of clinical endocrinology and metabolism 1986;63(5):1170-3.
-
1986: Melmed S; Fagin J; Leung M
Bromocriptine inhibits incorporation of [3H]thymidine into rat pituitary tumor cells.
Brain research 1986;369(1-2):83-90.
-
1986: Fagin J A; Litwak L; Steiner S; Gutman R A
Optimizing glycemic control: can insulin dependent diabetic patients rely on their perception of blood glucose fluctuations in order to make therapeutic decisions?
Diabetes research (Edinburgh, Scotland) 1986;3(3):139-44.
-
1986: Melmed S; Fagin J A
Isolation and characterization of rat-mouse somatic cell hybrids secreting growth hormone and prolactin.
Experimental cell research 1986;162(2):475-85.
-
1985: Gutman R A; Litwak L E; Fagin J A; Plantalech L; Steiner S
[Insulin portable pump vs. intensified conventional injections in diabetes]
Medicina 1985;45(3):225-30.
-
1983: Fagin J A; Litwak L; Gutman R A
Economic realities of home blood glucose monitoring.
Lancet 1983;2(8351):682-3.
-
1983: Day P F; Fagin J A; Gutman R A
Transient glucose intolerance in rats after a single injection of serum from a diabetic patient with an unusual insulin resistance.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1983;37(7):354-7.
-
1981: Fagin J; Friedman R; Fireman P
Allergic rhinitis.
Pediatric clinics of North America 1981;28(4):797-806.
-
1980: Fagin J; Bradley J; Williams D
Carbon monoxide poisoning secondary to inhaling methylene chloride.
British medical journal 1980;281(6253):1461.
Sign-in to see more
