FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Hassan Fahmi

Research Profile

Disorders

Anatomy

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Faezeh Vasheghani; Yue Zhang; Frank Beier; Meryem Blati; Hassan Fahmi; Johanne Martel-Pelletier; Roxana Monemdjou; Jean-Pierre Pelletier; Gemma Perez; René St-Arnaud; Mohit Kapoor
Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype.
Gladys Valverde-Franco; Koichi Matsuo; Jean-Pierre Pelletier; Hassan Fahmi; David Hum; Mohit Kapoor; Bertrand Lussier; Johanne Martel-Pelletier
In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.
Mireille Bentz; Hassan Fahmi; Julio C Fernandes; Florina Moldovan; Qin Shi; Charlotte Zaouter; Mohamed Benderdour
Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Hassan Fahmi (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Faezeh Vasheghani; Yue Zhang; Frank Beier; Meryem Blati; Hassan Fahmi; Johanne Martel-Pelletier; Roxana Monemdjou; Jean-Pierre Pelletier; Gemma Perez; René St-Arnaud; Mohit Kapoor
Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype.
The American journal of pathology 2013;182(4):1099-106.
2012: Gladys Valverde-Franco; Koichi Matsuo; Jean-Pierre Pelletier; Hassan Fahmi; David Hum; Mohit Kapoor; Bertrand Lussier; Johanne Martel-Pelletier
In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.
Arthritis and rheumatism 2012;64(11):3614-25.
2012: Mireille Bentz; Hassan Fahmi; Julio C Fernandes; Florina Moldovan; Qin Shi; Charlotte Zaouter; Mohamed Benderdour
Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes.
Journal of cellular biochemistry 2012;113(7):2256-67.
2012: Roxana Monemdjou; Jean-Pierre Pelletier; Gemma Perez; René St-Arnaud; Noboru Taniguchi; Faezeh Vasheghani; Frank Beier; Meryem Blati; Hassan Fahmi; Martin Lotz; Johanne Martel-Pelletier; Mohit Kapoor
Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model.
Arthritis and rheumatism 2012;64(5):1551-61.
2012: Mohit Kapoor; François Mineau; Jean-Pierre Pelletier; Hassan Fahmi; Johanne Martel-Pelletier
Glucosamine sulfate reduces prostaglandin E(2) production in osteoarthritic chondrocytes through inhibition of microsomal PGE synthase-1.
The Journal of rheumatology 2012;39(3):635-44.
2012: Sarah-Salwa Nebbaki; Jean-Pierre Pelletier; Mohit Kapoor; Johanne Martel-Pelletier; Hassan Afif; Mohamed Benderdour; Nicolas Duval; Fatima Ezzahra El Mansouri; Hassan Fahmi
Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes.
Arthritis research & therapy 2012;14(2):R69.
2011: Mohamed Benderdour; Hassan Fahmi; Julio C Fernandes; François Beaudet; Qin Shi
Nuclear receptor retinoid-related orphan receptor α1 modulates the metabolic activity of human osteoblasts.
Journal of cellular biochemistry 2011;112(8):2160-9.
2011: Nadia Zayed; Fatima Ezzahra El Mansouri; Nadir Chabane; Mohit Kapoor; Johanne Martel-Pelletier; Mohamed Benderdour; Jean-Pierre Pelletier; Nicolas Duval; Hassan Fahmi
Valproic acid suppresses interleukin-1ß-induced microsomal prostaglandin E2 synthase-1 expression in chondrocytes through upregulation of NAB1.
The Journal of rheumatology 2011;38(3):492-502.
2011: Matthew McCann; Roxana Monemdjou; Sunil K Parapuram; Gemma Perez; Xu Shi-wen; David J Abraham; Leslie J Crofford; Christopher P Denton; Hassan Fahmi; Parisa Ghassemi-Kakroodi; Fumiaki Kojima; Andrew Leask; Shangxi Liu; Johanne Martel-Pelletier; Mohit Kapoor
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis.
Arthritis research & therapy 2011;13(1):R6.
2011: Mohit Kapoor; Johanne Martel-Pelletier; Daniel Lajeunesse; Jean-Pierre Pelletier; Hassan Fahmi
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis.
Nature reviews. Rheumatology 2011;7(1):33-42.
2011: France Vaillancourt; Patrick Silva; Qin Shi; Hassan Fahmi; Julio C Fernandes; Mohamed Benderdour
Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis.
Journal of cellular biochemistry 2011;112(1):107-17.
2010: Rana El-Bikai; Mélanie Welman; Yoran Margaron; Jean-François Côté; Luke Macqueen; Michael D Buschmann; Hassan Fahmi; Qin Shi; Karim Maghni; Julio C Fernandes; Mohamed Benderdour
Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis.
Arthritis research & therapy 2010;12(5):R201.
2010: Shu-Huang Chen; Hassan Fahmi; Qin Shi; Mohamed Benderdour
Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes.
Arthritis research & therapy 2010;12(1):R21.
2009: Nadir Chabane; Xinfang Li; Hassan Fahmi
HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity.
Journal of cellular biochemistry 2009;106(3):453-63.
2009: Nadir Chabane; Nadia Zayed; Mohamed Benderdour; Johanne Martel-Pelletier; Jean-Pierre Pelletier; Nicolas Duval; Hassan Fahmi
Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis.
Arthritis research & therapy 2009;11(2):R44.
2008: N Chabane; N Zayed; Hassan Afif; L Mfuna-Endam; Mohamed Benderdour; Christelle Boileau; Johanne Martel-Pelletier; Jean-Pierre Pelletier; Nicolas Duval; Hassan Fahmi
Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2008;16(10):1267-74.
2008: Steeve Kwan Tat; Jean-Pierre Pelletier; Daniel Lajeunesse; Hassan Fahmi; Nicolas Duval; Johanne Martel-Pelletier
Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors.
Bone 2008;43(2):284-91.
2008: S Kwan Tat; Jean-Pierre Pelletier; Daniel Lajeunesse; Hassan Fahmi; Martin Lavigne; Johanne Martel-Pelletier
The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells.
Clinical and experimental rheumatology 2008;26(2):295-304.
2008: Nadia Zayed; Xinfang Li; Nadir Chabane; Mohamed Benderdour; Johanne Martel-Pelletier; Jean-Pierre Pelletier; Nicolas Duval; Hassan Fahmi
Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage.
Arthritis research & therapy 2008;10(6):R146.
2008: France Vaillancourt; Hassan Fahmi; Qin Shi; Patrick Lavigne; Pierre Ranger; Julio C Fernandes; Mohamed Benderdour
4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase.
Arthritis research & therapy 2008;10(5):R107.
2007: Christelle Boileau; Johanne Martel-Pelletier; Hassan Fahmi; François Mineau; Martin Boily; Jean-Pierre Pelletier
The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and catabolic pathways.
Arthritis and rheumatism 2007;56(7):2288-98.
2007: France Vaillancourt; Barbara Morquette; Qin Shi; Hassan Fahmi; Patrick Lavigne; John A Di Battista; Julio C Fernandes; Mohamed Benderdour
Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade.
Journal of cellular biochemistry 2007;100(5):1217-31.
2007: Christelle Boileau; Nathalie Amiable; Johanne Martel-Pelletier; Hassan Fahmi; Nicolas Duval; Jean-Pierre Pelletier
Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study.
Arthritis research & therapy 2007;9(6):R121.
2007: Steeve Kwan Tat; Jean-Pierre Pelletier; Josep Vergés; Daniel Lajeunesse; Eulàlia Montell; Hassan Fahmi; Martin Lavigne; Johanne Martel-Pelletier
Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study.
Arthritis research & therapy 2007;9(6):R117.
2007: Hassan Afif; Mohamed Benderdour; Leandra Mfuna-Endam; Johanne Martel-Pelletier; Jean-Pierre Pelletier; Nicolas Duval; Hassan Fahmi
Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes.
Arthritis research & therapy 2007;9(2):R31.
2006: Saranette Cheng; Hassan Afif; Johanne Martel-Pelletier; Mohamed Benderdour; Jean-Pierre Pelletier; G Hilal; P Haraoui; Jean-Pierre Raynauld; Denis Choquette; Hassan Fahmi
Association of polymorphisms in the peroxisome proliferator-activated receptor gamma gene and osteoarthritis of the knee.
Annals of the rheumatic diseases 2006;65(10):1394-7.
2006: Johanne Martel-Pelletier; Daniel Lajeunesse; Hassan Fahmi; Ginette Tardif; Jean-Pierre Pelletier
New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets.
Current rheumatology reports 2006;8(1):30-6.
2006: Qin Shi; France Vaillancourt; Véronique Côté; Hassan Fahmi; Patrick Lavigne; Hassan Afif; John A Di Battista; Julio C Fernandes; Mohamed Benderdour
Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal.
Arthritis research & therapy 2006;8(6):R159.
2005: Christelle Boileau; Jean-Pierre Pelletier; Ginette Tardif; Hassan Fahmi; Stefan Laufer; Martin Lavigne; Johanne Martel-Pelletier
The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.
Annals of the rheumatic diseases 2005;64(6):891-8.
2005: Xinfang Li; Hassan Afif; Saranette Cheng; Johanne Martel-Pelletier; Jean-Pierre Pelletier; Pierre Ranger; Hassan Fahmi
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.
The Journal of rheumatology 2005;32(5):887-95.
2005: Katherine Farrajota; Saranette Cheng; Johanne Martel-Pelletier; Hassan Afif; Jean-Pierre Pelletier; Xinfang Li; Pierre Ranger; Hassan Fahmi
Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism.
Arthritis and rheumatism 2005;52(1):94-104.
2004: Johanne Martel-Pelletier; François Mineau; Hassan Fahmi; Stefan Laufer; Pascal Reboul; Christelle Boileau; Martin Lavigne; Jean-Pierre Pelletier
Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.
Arthritis and rheumatism 2004;50(12):3925-33.
2004: Hassan Fahmi
mPGES-1 as a novel target for arthritis.
Current opinion in rheumatology 2004;16(5):623-7.
2004: Saranette Cheng; Hassan Afif; Johanne Martel-Pelletier; Jean-Pierre Pelletier; Xinfang Li; Katherine Farrajota; Martin Lavigne; Hassan Fahmi
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.
The Journal of biological chemistry 2004;279(21):22057-65.
2003: Johanne Martel-Pelletier; Jean-Pierre Pelletier; Hassan Fahmi
Cyclooxygenase-2 and prostaglandins in articular tissues.
Seminars in arthritis and rheumatism 2003;33(3):155-67.
2002: Hassan Fahmi; Jean-Pierre Pelletier; François Mineau; Johanne Martel-Pelletier
15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(11):845-8.
2002: Hassan Fahmi; Jean-Pierre Pelletier; John A Di Battista; Herman S Cheung; Julio C Fernandes; Johanne Martel-Pelletier
Peroxisome proliferator-activated receptor gamma activators inhibit MMP-1 production in human synovial fibroblasts likely by reducing the binding of the activator protein 1.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(2):100-8.
2002: Tanja Kalajdzic; Wissam H Faour; Qing Wen He; Hassan Fahmi; Johanne Martel-Pelletier; Jean-Pierre Pelletier; John A Di Battista
Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism.
Arthritis and rheumatism 2002;46(2):494-506.
2001: Hassan Fahmi; Y He; M Zhang; Johanne Martel-Pelletier; Jean-Pierre Pelletier; John A Di Battista
Nimesulide reduces interleukin-1beta-induced cyclooxygenase-2 gene expression in human synovial fibroblasts.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(4):332-40.
2001: Hassan Fahmi; John A Di Battista; Jean-Pierre Pelletier; François Mineau; Pierre Ranger; Johanne Martel-Pelletier
Peroxisome proliferator--activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes.
Arthritis and rheumatism 2001;44(3):595-607.
2001: John A Di Battista; Hassan Fahmi; Y He; M Zhang; Johanne Martel-Pelletier; Jean-Pierre Pelletier
Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.
Clinical and experimental rheumatology 2001;19(1 Suppl 22):S3-5.