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Michael Andreeff

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Disorders

Anatomy

Physiology

Neoplasm Drug Resistance

Procedures

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Mice

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Phosphorylation

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Publications

TOP 3
Schimmer Aaron D; Estey Elihu H; Borthakur Gautam; Carter Bing Z; Schiller Gary J; Tallman Martin S; Altman Jessica K; Karp Judith E; Kassis Jeannine; Hedley David W; Brandwein Joseph; Xu Wei; Mak Duncan H; LaCasse Eric; Jacob Christine; Morris Stephen J; Jolivet Jacques; Andreeff Michael
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
Kidd Shannon; Spaeth Erika; Dembinski Jennifer L; Dietrich Martin; Watson Keri; Klopp Ann; Battula Venkata Lokesh; Weil Micheal; Andreeff Michael; Marini Frank C
Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging.
Carter B Z; Mak D H; Woessner R; Gross S; Schober W D; Estrov Z; Kantarjian H; Andreeff M
Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells.

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All Publications

2009: Schimmer Aaron D; Estey Elihu H; Borthakur Gautam; Carter Bing Z; Schiller Gary J; Tallman Martin S; Altman Jessica K; Karp Judith E; Kassis Jeannine; Hedley David W; Brandwein Joseph; Xu Wei; Mak Duncan H; LaCasse Eric; Jacob Christine; Morris Stephen J; Jolivet Jacques; Andreeff Michael
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(28):4741-6.
2009: Kidd Shannon; Spaeth Erika; Dembinski Jennifer L; Dietrich Martin; Watson Keri; Klopp Ann; Battula Venkata Lokesh; Weil Micheal; Andreeff Michael; Marini Frank C
Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging.
Stem cells (Dayton, Ohio) 2009;27(10):2614-23.
2009: Carter B Z; Mak D H; Woessner R; Gross S; Schober W D; Estrov Z; Kantarjian H; Andreeff M
Inhibition of KSP by ARRY-520 induces cell cycle block and cell death via the mitochondrial pathway in AML cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(10):1755-62.
2009: Mak Duncan H; Schober Wendy D; Chen Wenjing; Konopleva Marina; Cortes Jorge; Kantarjian Hagop M; Andreeff Michael; Carter Bing Z
Triptolide induces cell death independent of cellular responses to imatinib in blast crisis chronic myelogenous leukemia cells including quiescent CD34+ primitive progenitor cells.
Molecular cancer therapeutics 2009;8(9):2509-16.
2009: Konopleva Marina; Tabe Yoko; Zeng Zhihong; Andreeff Michael
Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2009;12(4-5):103-13.
2009: Kojima Kensuke; Shimanuki Masaya; Shikami Masato; Andreeff Michael; Nakakuma Hideki
Cyclin-dependent kinase 1 inhibitor RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis in AML.
Cancer science 2009;100(6):1128-36.
2009: Garzon Ramiro; Liu Shujun; Fabbri Muller; Liu Zhongfa; Heaphy Catherine E A; Callegari Elisa; Schwind Sebastian; Pang Jiuxia; Yu Jianhua; Muthusamy Natarajan; Havelange Violaine; Volinia Stefano; Blum William; Rush Laura J; Perrotti Danilo; Andreeff Michael; Bloomfield Clara D; Byrd John C; Chan Kenneth; Wu Lai-Chu; Croce Carlo M; Marcucci Guido
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.
Blood 2009;113(25):6411-8.
2009: Zeng Zhihong; Shi Yue Xi; Samudio Ismael J; Wang Rui-Yu; Ling Xiaoyang; Frolova Olga; Levis Mark; Rubin Joshua B; Negrin Robert R; Estey Elihu H; Konoplev Sergej; Andreeff Michael; Konopleva Marina
Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.
Blood 2009;113(24):6215-24.
2009: Drakos E; Atsaves V; Li J; Leventaki V; Andreeff M; Medeiros L J; Rassidakis G Z
Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009;23(4):784-90.
2009: Samudio Ismael; Fiegl Michael; Andreeff Michael
Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolism.
Cancer research 2009;69(6):2163-6.
2009: Lu Jing; Tan Ming; Huang Wen-Chien; Li Ping; Guo Hua; Tseng Ling-Ming; Su Xiao-hua; Yang Wen-Tao; Treekitkarnmongkol Warapen; Andreeff Michael; Symmans Fraser; Yu Dihua
Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(4):1326-34.
2009: Fiegl Michael; Samudio Ismael; Clise-Dwyer Karen; Burks Jared K; Mnjoyan Zakar; Andreeff Michael
CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure.
Blood 2009;113(7):1504-12.
2009: Kornblau Steven M; Tibes Raoul; Qiu Yi Hua; Chen Wenjing; Kantarjian Hagop M; Andreeff Michael; Coombes Kevin R; Mills Gordon B
Functional proteomic profiling of AML predicts response and survival.
Blood 2009;113(1):154-64.
2009: Spaeth Erika L; Dembinski Jennifer L; Sasser A Kate; Watson Keri; Klopp Ann; Hall Brett; Andreeff Michael; Marini Frank
Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression.
PloS one 2009;4(4):e4992.
2009: Freudenberg Robert; Andreeff Michael; Oehme Liane; Kotzerke Jörg
[Dosimetry of cell-monolayers in multiwell plates]
Nuklearmedizin. Nuclear medicine 2009;48(3):120-6.
2008: Elsawa Sherine F; Novak Anne J; Grote Deanna; Konopleva Marina; Andreeff Michael; Witzig Thomas E; Ansell Stephen M
CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia.
Leukemia research 2008;32(12):1895-902.
2008: Zuderman Lidiya; Liepe Knut; Zöphel Klaus; Andreeff Michael; Kotzerke Joerg; Luboldt Wolfgang
Radiosynoviorthesis (RSO): influencing factors and therapy monitoring.
Annals of nuclear medicine 2008;22(9):735-41.
2008: Andreeff M; Ruvolo V; Gadgil S; Zeng C; Coombes K; Chen W; Kornblau S; Barón A E; Drabkin H A
HOX expression patterns identify a common signature for favorable AML.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(11):2041-7.
2008: Kojima Kensuke; Konopleva Marina; Tsao Twee; Nakakuma Hideki; Andreeff Michael
Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia.
Blood 2008;112(7):2886-95.
2008: Samudio Ismael; Fiegl Michael; McQueen Teresa; Clise-Dwyer Karen; Andreeff Michael
The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation.
Cancer research 2008;68(13):5198-205.
2008: Xu Yuanyuan; Tabe Yoko; Jin Linhua; Watt Julie; McQueen Teresa; Ohsaka Akimichi; Andreeff Michael; Konopleva Marina
TGF-beta receptor kinase inhibitor LY2109761 reverses the anti-apoptotic effects of TGF-beta1 in myelo-monocytic leukaemic cells co-cultured with stromal cells.
British journal of haematology 2008;142(2):192-201.
2008: Kuroda Junya; Kamitsuji Yuri; Kimura Shinya; Ashihara Eishi; Kawata Eri; Nakagawa Yoko; Takeuichi Miki; Murotani Yoshihide; Yokota Asumi; Tanaka Ruriko; Andreeff Michael; Taniwaki Masafumi; Maekawa Taira
Anti-myeloma effect of homoharringtonine with concomitant targeting of the myeloma-promoting molecules, Mcl-1, XIAP, and beta-catenin.
International journal of hematology 2008;87(5):507-15.
2008: Fabbri M; Garzon R; Andreeff M; Kantarjian H M; Garcia-Manero G; Calin G A
MicroRNAs and noncoding RNAs in hematological malignancies: molecular, clinical and therapeutic implications.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(6):1095-105.
2008: Krajewska Maryla; Kitada Shinichi; Winter Jane N; Variakojis Daina; Lichtenstein Alan; Zhai Dayong; Cuddy Michael; Huang Xianshu; Luciano Frederic; Baker Cheryl H; Kim Hoguen; Shin Eunah; Kennedy Susan; Olson Allen H; Badzio Andrzej; Jassem Jacek; Meinhold-Heerlein Ivo; Duffy Michael J; Schimmer Aaron D; Tsao Ming; Brown Ewan; Sawyers Anne; Andreeff Michael; Mercola Dan; Krajewski Stan; Reed John C
Bcl-B expression in human epithelial and nonepithelial malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(10):3011-21.
2008: Samudio Ismael; Kurinna Svitlana; Ruvolo Peter; Korchin Borys; Kantarjian Hagop; Beran Miloslav; Dunner Kenneth; Kondo Seiji; Andreeff Michael; Konopleva Marina
Inhibition of mitochondrial metabolism by methyl-2-cyano-3,12-dioxooleana-1,9-diene-28-oate induces apoptotic or autophagic cell death in chronic myeloid leukemia cells.
Molecular cancer therapeutics 2008;7(5):1130-9.
2008: Konopleva Marina; Watt Julie; Contractor Rooha; Tsao Twee; Harris David; Estrov Zeev; Bornmann William; Kantarjian Hagop; Viallet Jean; Samudio Ismael; Andreeff Michael
Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).
Cancer research 2008;68(9):3413-20.
2008: Spaeth E; Klopp A; Dembinski J; Andreeff M; Marini F
Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells.
Gene therapy 2008;15(10):730-8.
2008: Zhang W; Konopleva M; Ruvolo V R; McQueen T; Evans R L; Bornmann W G; McCubrey J; Cortes J; Andreeff M
Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(4):808-18.
2008: Carter Bing Z; Mak Duncan H; Schober Wendy D; Dietrich Martin F; Pinilla Clemencia; Vassilev Lyubomir T; Reed John C; Andreeff Michael
Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5.
Blood 2008;111(7):3742-50.
2008: Garzon Ramiro; Volinia Stefano; Liu Chang-Gong; Fernandez-Cymering Cecilia; Palumbo Tiziana; Pichiorri Flavia; Fabbri Muller; Coombes Kevin; Alder Hansjuerg; Nakamura Tatsuya; Flomenberg Neal; Marcucci Guido; Calin George A; Kornblau Steven M; Kantarjian Hagop; Bloomfield Clara D; Andreeff Michael; Croce Carlo M
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.
Blood 2008;111(6):3183-9.
2008: Zhang Weiguo; Konopleva Marina; Shi Yue-xi; McQueen Teresa; Harris David; Ling Xiaoyang; Estrov Zeev; Quintás-Cardama Alfonso; Small Donald; Cortes Jorge; Andreeff Michael
Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia.
Journal of the National Cancer Institute 2008;100(3):184-98.
2008: Jin Linhua; Tabe Yoko; Konoplev Sergej; Xu Yuanyuan; Leysath Clinton E; Lu Hongbo; Kimura Shinya; Ohsaka Akimichi; Rios Mary-Beth; Calvert Leslie; Kantarjian Hagop; Andreeff Michael; Konopleva Marina
CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells.
Molecular cancer therapeutics 2008;7(1):48-58.
2008: Kuroda Junya; Kimura Shinya; Andreeff Michael; Ashihara Eishi; Kamitsuji Yuri; Yokota Asumi; Kawata Eri; Takeuchi Miki; Tanaka Ruriko; Murotani Yoshihide; Matsumoto Yosuke; Tanaka Hideo; Strasser Andreas; Taniwaki Masafumi; Maekawa Taira
ABT-737 is a useful component of combinatory chemotherapies for chronic myeloid leukaemias with diverse drug-resistance mechanisms.
British journal of haematology 2008;140(2):181-90.
2007: Klopp Ann H; Spaeth Erika L; Dembinski Jennifer L; Woodward Wendy A; Munshi Anupama; Meyn Raymond E; Cox James D; Andreeff Michael; Marini Frank C
Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment.
Cancer research 2007;67(24):11687-95.
2007: Tabe Yoko; Konopleva Marina; Kondo Yutaka; Contractor Rooha; Tsao Twee; Konoplev Sergej; Shi Yuexi; Ling Xiaoyang; Watt Julie C; Tsutsumi-Ishii Yuko; Ohsaka Akimichi; Nagaoka Isao; Issa Jean-Pierre J; Kogan Scott C; Andreeff Michael
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
Cancer biology & therapy 2007;6(12):1967-77.
2007: Koschmieder Steffen; D'Alò Francesco; Radomska Hanna; Schöneich Christine; Chang Ji Suk; Konopleva Marina; Kobayashi Susumu; Levantini Elena; Suh Nanjoo; Di Ruscio Annalisa; Voso Maria Teresa; Watt Julie C; Santhanam Ramasamy; Sargin Bülent; Kantarjian Hagop; Andreeff Michael; Sporn Michael B; Perrotti Danilo; Berdel Wolfgang E; Müller-Tidow Carsten; Serve Hubert; Tenen Daniel G
CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.
Blood 2007;110(10):3695-705.
2007: Tabe Y; Jin L; Contractor R; Gold D; Ruvolo P; Radke S; Xu Y; Tsutusmi-Ishii Y; Miyake K; Miyake N; Kondo S; Ohsaka A; Nagaoka I; Andreeff M; Konopleva M
Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1.
Cell death and differentiation 2007;14(8):1443-56.
2007: Hall Brett; Dembinski Jennifer; Sasser A Kate; Studeny Matus; Andreeff Michael; Marini Frank
Mesenchymal stem cells in cancer: tumor-associated fibroblasts and cell-based delivery vehicles.
International journal of hematology 2007;86(1):8-16.
2007: Konopleva Marina; Andreeff Michael
Targeting the leukemia microenvironment.
Current drug targets 2007;8(6):685-701.
2007: Drakos Elias; Thomaides Athanasios; Medeiros L Jeffrey; Li Jiang; Leventaki Vasiliki; Konopleva Marina; Andreeff Michael; Rassidakis George Z
Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(11):3380-7.
2007: Mullican Shannon E; Zhang Shuo; Konopleva Marina; Ruvolo Vivian; Andreeff Michael; Milbrandt Jeffrey; Conneely Orla M
Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.
Nature medicine 2007;13(6):730-5.
2007: Gregorj Chiara; Ricciardi Maria R; Petrucci Maria T; Scerpa Maria C; De Cave Fabiana; Fazi Paola; Vignetti Marco; Vitale Antonella; Mancini Marco; Cimino Giuseppe; Palmieri Salvatore; Di Raimondo Francesco; Specchia Giorgina; Fabbiano Francesco; Cantore Nicola; Mosna Federico; Camera Andrea; Luppi Mario; Annino Luciana; Miraglia Eustachio; Fioritoni Giuseppe; Ronco Francesca; Meloni Giovanna; Mandelli Franco; Andreeff Michael; Milella Michele; Foà Robin; Tafuri Agostino;
ERK1/2 phosphorylation is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia.
Blood 2007;109(12):5473-6.
2007: Garzon R; Pichiorri F; Palumbo T; Visentini M; Aqeilan R; Cimmino A; Wang H; Sun H; Volinia S; Alder H; Calin G A; Liu C-G; Andreeff M; Croce C M
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia.
Oncogene 2007;26(28):4148-57.
2007: Ling Xiaoyang; Konopleva Marina; Zeng Zhihong; Ruvolo Vivian; Stephens L Clifton; Schober Wendy; McQueen Teresa; Dietrich Martin; Madden Timothy L; Andreeff Michael
The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.
Cancer research 2007;67(9):4210-8.
2007: Sun Kai; Li Minghui; Konopleva Marina; Konoplev Sergej; Stephens L Clifton; Kornblau Steven M; Frolova Olga; Wilkins Danice E C; Ma Weihong; Welniak Lisbeth A; Andreeff Michael; Murphy William J
The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(5):521-9.
2007: Mak Duncan H; Schober Wendy D; Chen Wenjing; Heller Jonathan; Andreeff Michael; Carter Bing Z
Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of Cdc2 and survivin.
Leukemia & lymphoma 2007;48(4):774-85.
2007: Kojima Kensuke; Konopleva Marina; Samudio Ismael J; Ruvolo Vivian; Andreeff Michael
Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells.
Cancer research 2007;67(7):3210-9.
2007: Zeng Zhihong; Sarbassov Dos D; Samudio Ismael J; Yee Karen W L; Munsell Mark F; Ellen Jackson C; Giles Francis J; Sabatini David M; Andreeff Michael; Konopleva Marina
Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
Blood 2007;109(8):3509-12.
2007: Konoplev Sergej; Rassidakis Georgios Z; Estey Elihu; Kantarjian Hagop; Liakou Chrysoula I; Huang Xuelin; Xiao Lianchun; Andreeff Michael; Konopleva Marina; Medeiros L Jeffrey
Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype.
Cancer 2007;109(6):1152-6.
2007: Milella Michele; Konopleva Marina; Precupanu Cristina M; Tabe Yoko; Ricciardi Maria Rosaria; Gregorj Chiara; Collins Steven J; Carter Bing Z; D'Angelo Carmen; Petrucci Maria Teresa; Foà Robin; Cognetti Francesco; Tafuri Agostino; Andreeff Michael
MEK blockade converts AML differentiating response to retinoids into extensive apoptosis.
Blood 2007;109(5):2121-9.
2007: Kuang S-Q; Ling X; Sanchez-Gonzalez B; Yang H; Andreeff M; Garcia-Manero G
Differential tumor suppressor properties and transforming growth factor-beta responsiveness of p57KIP2 in leukemia cells with aberrant p57KIP2 promoter DNA methylation.
Oncogene 2007;26(10):1439-48.
2007: Brookes Paul S; Morse Kimberly; Ray Denise; Tompkins Andrew; Young Sara M; Hilchey Shannon; Salim Suhail; Konopleva Marina; Andreeff Michael; Phipps Richard; Bernstein Steven H
The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and its derivatives elicit human lymphoid cell apoptosis through a novel pathway involving the unregulated mitochondrial permeability transition pore.
Cancer research 2007;67(4):1793-802.
2007: Tabe Yoko; Jin Linhua; Tsutsumi-Ishii Yuko; Xu Yuanyuan; McQueen Teresa; Priebe Waldemar; Mills Gordon B; Ohsaka Akimichi; Nagaoka Isao; Andreeff Michael; Konopleva Marina
Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells.
Cancer research 2007;67(2):684-94.
2007: Kress Christina L; Konopleva Marina; Martínez-García Vanesa; Krajewska Maryla; Lefebvre Sophie; Hyer Marc L; McQueen Teresa; Andreeff Michael; Reed John C; Zapata Juan M
Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.
PloS one 2007;2(6):e559.
2006: Kornblau Steven M; Qiu Yi Hua; Bekele B N; Cade Jenny Straka; Zhou Xian; Harris David; Jackson C Ellen; Estrov Zeev; Andreeff Michael
Studying the right cell in acute myelogenous leukemia: dynamic changes of apoptosis and signal transduction pathway protein expression in chemotherapy resistant ex-vivo selected "survivor cells".
Cell cycle (Georgetown, Tex.) 2006;5(23):2769-77.
2006: Kojima Kensuke; Konopleva Marina; Samudio Ismael J; Schober Wendy D; Bornmann William G; Andreeff Michael
Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML.
Cell cycle (Georgetown, Tex.) 2006;5(23):2778-86.
2006: Zeng Zhihong; Samudio Ismael J; Munsell Mark; An Jing; Huang Ziwei; Estey Elihu; Andreeff Michael; Konopleva Marina
Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.
Molecular cancer therapeutics 2006;5(12):3113-21.
2006: Konopleva Marina; Contractor Rooha; Tsao Twee; Samudio Ismael; Ruvolo Peter P; Kitada Shinichi; Deng Xingming; Zhai Dayong; Shi Yue-Xi; Sneed Thomas; Verhaegen Monique; Soengas Maria; Ruvolo Vivian R; McQueen Teresa; Schober Wendy D; Watt Julie C; Jiffar Tilahun; Ling Xiaoyang; Marini Frank C; Harris David; Dietrich Martin; Estrov Zeev; McCubrey James; May W Stratford; Reed John C; Andreeff Michael
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Cancer cell 2006;10(5):375-88.
2006: Sah Nand K; Munshi Anupama; Hobbs Marvette; Carter Bing Z; Andreeff Michael; Meyn Raymond E
Effect of downregulation of survivin expression on radiosensitivity of human epidermoid carcinoma cells.
International journal of radiation oncology, biology, physics 2006;66(3):852-9.
2006: Tibes Raoul; Qiu Yihua; Lu Yiling; Hennessy Bryan; Andreeff Michael; Mills Gordon B; Kornblau Steven M
Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells.
Molecular cancer therapeutics 2006;5(10):2512-21.
2006: Carter Bing Z; Mak Duncan H; Shi Yuexi; Schober Wendy D; Wang Rui-Yu; Konopleva Marina; Koller Erich; Dean Nicholas M; Andreeff Michael
Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance.
Cell cycle (Georgetown, Tex.) 2006;5(19):2223-9.
2006: Tabe Yoko; Konopleva Marina; Kondo Yutaka; Contractor Rooha; Jin Linhua; Ruvolo Vivian; Tsutsumi-Ishii Yuko; Miyake Kazunori; Miyake Noriko; Ohsaka Akimichi; Nagaoka Isao; Issa Jean-Pierre J; Andreeff Michael
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
Annals of hematology 2006;85(10):689-704.
2006: Kornblau Steven M; Womble Matthew; Qiu Yi Hua; Jackson C Ellen; Chen Wenjing; Konopleva Marina; Estey Elihu H; Andreeff Michael
Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia.
Blood 2006;108(7):2358-65.
2006: Yee Karen W L; Zeng Zhihong; Konopleva Marina; Verstovsek Srdan; Ravandi Farhad; Ferrajoli Alessandra; Thomas Deborah; Wierda William; Apostolidou Efrosyni; Albitar Maher; O'Brien Susan; Andreeff Michael; Giles Francis J
Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5165-73.
2006: Gyurkocza Boglarka; Plescia Janet; Raskett Christopher M; Garlick David S; Lowry Philip A; Carter Bing Z; Andreeff Michael; Meli Massimiliano; Colombo Giorgio; Altieri Dario C
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
Journal of the National Cancer Institute 2006;98(15):1068-77.
2006: Kojima Kensuke; Konopleva Marina; McQueen Teresa; O'Brien Susan; Plunkett William; Andreeff Michael
Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia.
Blood 2006;108(3):993-1000.
2006: Kurinna S; Konopleva M; Palla S L; Chen W; Kornblau S; Contractor R; Deng X; May W S; Andreeff M; Ruvolo P P
Bcl2 phosphorylation and active PKC alpha are associated with poor survival in AML.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(7):1316-9.
2006: Carter Bing Z; Mak Duncan H; Schober Wendy D; McQueen Teresa; Harris David; Estrov Zeev; Evans Randall L; Andreeff Michael
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.
Blood 2006;108(2):630-7.
2006: Ling X; Wang Y; Dietrich M F; Andreeff M; Arlinghaus R B
Vaccination with leukemia cells expressing cell-surface-associated GM-CSF blocks leukemia induction in immunocompetent mice.
Oncogene 2006;25(32):4483-90.
2006: Yee Karen W L; Cortes Jorge; Ferrajoli Alessandra; Garcia-Manero Guillermo; Verstovsek Srdan; Wierda William; Thomas Deborah; Faderl Stefan; King Ivan; O'brien Susan M; Jeha Sima; Andreeff Michael; Cahill Ann; Sznol Mario; Giles Francis J
Triapine and cytarabine is an active combination in patients with acute leukemia or myelodysplastic syndrome.
Leukemia research 2006;30(7):813-22.
2006: Tsimberidou Apostolia-Maria; Tirado-Gomez Maribel; Andreeff Michael; O'Brien Susan; Kantarjian Hagop; Keating Michael; Lopez-Berestein Gabriel; Estey Elihu
Single-agent liposomal all-trans retinoic acid can cure some patients with untreated acute promyelocytic leukemia: an update of The University of Texas M. D. Anderson Cancer Center Series.
Leukemia & lymphoma 2006;47(6):1062-8.
2006: Zeng Zhihong; Samudio Ismael J; Zhang Weiguo; Estrov Zeev; Pelicano Hélène; Harris David; Frolova Olga; Hail Numsen; Chen Wenjing; Kornblau Steven M; Huang Peng; Lu Yiling; Mills Gordon B; Andreeff Michael; Konopleva Marina
Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia.
Cancer research 2006;66(7):3737-46.
2006: Pelicano H; Carew J S; McQueen T J; Andreeff M; Plunkett W; Keating M J; Huang P
Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(4):610-9.
2006: Samudio Ismael; Konopleva Marina; Pelicano Helene; Huang Peng; Frolova Olga; Bornmann William; Ying Yunming; Evans Randall; Contractor Rooha; Andreeff Michael
A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis.
Molecular pharmacology 2006;69(4):1182-93.
2006: Shishodia Shishir; Sethi Gautam; Konopleva Marina; Andreeff Michael; Aggarwal Bharat B
A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1828-38.
2006: Garzon Ramiro; Pichiorri Flavia; Palumbo Tiziana; Iuliano Rodolfo; Cimmino Amelia; Aqeilan Rami; Volinia Stefano; Bhatt Darshna; Alder Hansjuerg; Marcucci Guido; Calin George A; Liu Chang-Gong; Bloomfield Clara D; Andreeff Michael; Croce Carlo M
MicroRNA fingerprints during human megakaryocytopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(13):5078-83.
2006: Sampath Deepa; Cortes Jorge; Estrov Zeev; Du Min; Shi Zheng; Andreeff Michael; Gandhi Varsha; Plunkett William
Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial.
Blood 2006;107(6):2517-24.
2006: Konopleva Marina; Zhang Weiguo; Shi Yue-Xi; McQueen Teresa; Tsao Twee; Abdelrahim Maen; Munsell Mark F; Johansen Mary; Yu Dihua; Madden Timothy; Safe Stephen H; Hung Mien-Chie; Andreeff Michael
Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells.
Molecular cancer therapeutics 2006;5(2):317-28.
2006: Inoue Satoshi; Shanker Manish; Miyahara Ryo; Gopalan Began; Patel Suraag; Oida Yasuhisa; Branch Cynthia D; Munshi Anupama; Meyn Raymond E; Andreeff Michael; Tanaka Fumihiro; Mhashilkar Abner M; Chada Sunil; Ramesh Rajagopal
MDA-7/IL-24-based cancer gene therapy: translation from the laboratory to the clinic.
Current gene therapy 2006;6(1):73-91.
2006: Carter Bing Z; Mak Duncan H; Schober Wendy D; Cabreira-Hansen Maria; Beran Miloslav; McQueen Teresa; Chen Wenjing; Andreeff Michael
Regulation of survivin expression through Bcr-Abl/MAPK cascade: targeting survivin overcomes imatinib resistance and increases imatinib sensitivity in imatinib-responsive CML cells.
Blood 2006;107(4):1555-63.
2006: Tabe Yoko; Konopleva Marina; Contractor Rooha; Munsell Mark; Schober Wendy D; Jin Linhua; Tsutsumi-Ishii Yuko; Nagaoka Isao; Igari Jun; Andreeff Michael
Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells.
Blood 2006;107(4):1546-54.
2005: Samudio Ismael; Konopleva Marina; Safe Stephen; McQueen Teresa; Andreeff Michael
Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure.
Molecular cancer therapeutics 2005;4(12):1982-92.
2005: Konopleva Marina; Shi Yuexi; Steelman Linda S; Shelton John G; Munsell Mark; Marini Frank; McQueen Teresa; Contractor Rooha; McCubrey James A; Andreeff Michael
Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
Cancer research 2005;65(21):9962-70.
2005: Zhang W; McQueen T; Schober W; Rassidakis G; Andreeff M; Konopleva M
Leukotriene B4 receptor inhibitor LY293111 induces cell cycle arrest and apoptosis in human anaplastic large-cell lymphoma cells via JNK phosphorylation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(11):1977-84.
2005: Kojima Kensuke; Konopleva Marina; Samudio Ismael J; Shikami Masato; Cabreira-Hansen Maria; McQueen Teresa; Ruvolo Vivian; Tsao Twee; Zeng Zhihong; Vassilev Lyubomir T; Andreeff Michael
MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.
Blood 2005;106(9):3150-9.
2005: Okcu Mehmet Fatih; Wang Rui-Yu; Bueso-Ramos Carlos; Schober Wendy; Weidner Douglas; Andrassy Richard; Blakely Martin; Russell Heidi; Ozkan Alp; Kuttesch John; Andreeff Michael; Chan Ka Wah; Ater Joann
Flow cytometry and fluorescence in situ hybridization to detect residual neuroblastoma cells in bone marrow.
Pediatric blood & cancer 2005;45(6):787-95.
2005: Biagi Ettore; Rousseau Raphael; Yvon Eric; Schwartz Mary; Dotti Gianpietro; Foster Aaron; Havlik-Cooper Diana; Grilley Bambi; Gee Adrian; Baker Kelty; Carrum George; Rice Lawrence; Andreeff Michael; Popat Uday; Brenner Malcolm
Responses to human CD40 ligand/human interleukin-2 autologous cell vaccine in patients with B-cell chronic lymphocytic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 1):6916-23.
2005: Samudio Ismael; Konopleva Marina; Hail Numsen; Shi Yue-Xi; McQueen Teresa; Hsu Timothy; Evans Randall; Honda Tadashi; Gribble Gordon W; Sporn Michael; Gilbert Hiram F; Safe Stephen; Andreeff Michael
2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
The Journal of biological chemistry 2005;280(43):36273-82.
2005: Ricciardi M R; McQueen T; Chism D; Milella M; Estey E; Kaldjian E; Sebolt-Leopold J; Konopleva M; Andreeff M
Quantitative single cell determination of ERK phosphorylation and regulation in relapsed and refractory primary acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(9):1543-9.
2005: Georgakis Georgios V; Li Yang; Humphreys Robin; Andreeff Michael; O'Brien Susan; Younes Mamoun; Carbone Antonino; Albert Vivian; Younes Anas
Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death.
British journal of haematology 2005;130(4):501-10.
2005: Liepe Knut; Andreeff Michael; Wunderlich Gerd; Kotzerke Joerg
Radiation protection in radiosynovectomy of the knee.
Health physics 2005;89(2):151-4.
2005: Jabbour Elias; Verstovsek Srdan; Giles Francis; Gandhi Varsha; Cortes Jorge; O'Brien Susan; Plunkett William; Garcia-Manero Guillermo; Jackson C Ellen; Kantarjian Hagop; Andreeff Michael
2-Chlorodeoxyadenosine and cytarabine combination therapy for idiopathic hypereosinophilic syndrome.
Cancer 2005;104(3):541-6.
2005: Konopleva M; Contractor R; Kurinna S M; Chen W; Andreeff M; Ruvolo P P
The novel triterpenoid CDDO-Me suppresses MAPK pathways and promotes p38 activation in acute myeloid leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(8):1350-4.
2005: Takada Yasunari; Andreeff Michael; Aggarwal Bharat B
Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
Blood 2005;106(2):641-9.
2005: Keating Michael J; O'Brien Susan; Albitar Maher; Lerner Susan; Plunkett William; Giles Francis; Andreeff Michael; Cortes Jorge; Faderl Stefan; Thomas Deborah; Koller Charles; Wierda William; Detry Michelle A; Lynn Alice; Kantarjian Hagop
Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(18):4079-88.
2005: Carter Bing Z; Gronda Marcela; Wang Zhiliang; Welsh Kate; Pinilla Clemencia; Andreeff Michael; Schober Wendy D; Nefzi Adel; Pond Gregory R; Mawji Imtiaz A; Houghten Richard A; Ostresh John; Brandwein Joseph; Minden Mark D; Schuh Andre C; Wells Richard A; Messner Hans; Chun Kathy; Reed John C; Schimmer Aaron D
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Blood 2005;105(10):4043-50.
2005: Nakamizo Akira; Marini Frank; Amano Toshiyuki; Khan Asadullah; Studeny Matus; Gumin Joy; Chen Julianne; Hentschel Stephen; Vecil Giacomo; Dembinski Jennifer; Andreeff Michael; Lang Frederick F
Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas.
Cancer research 2005;65(8):3307-18.
2005: Contractor Rooha; Samudio Ismael J; Estrov Zeev; Harris David; McCubrey James A; Safe Stephen H; Andreeff Michael; Konopleva Marina
A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia.
Cancer research 2005;65(7):2890-8.
2005: Milella M; Precupanu C M; Gregorj C; Ricciardi M R; Petrucci M T; Kornblau S M; Tafuri A; Andreeff M
Beyond single pathway inhibition: MEK inhibitors as a platform for the development of pharmacological combinations with synergistic anti-leukemic effects.
Current pharmaceutical design 2005;11(21):2779-95.
2004: Yotnda P; Zompeta C; Heslop H E; Andreeff M; Brenner M K; Marini F
Comparison of the efficiency of transduction of leukemic cells by fiber-modified adenoviruses.
Human gene therapy 2004;15(12):1229-42.
2004: Studeny Matus; Marini Frank C; Dembinski Jennifer L; Zompetta Claudia; Cabreira-Hansen Maria; Bekele Benjamin Nebiyou; Champlin Richard E; Andreeff Michael
Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents.
Journal of the National Cancer Institute 2004;96(21):1593-603.
2004: Konopleva Marina; Tsao Twee; Estrov Zeev; Lee Ruey-min; Wang Rui-Yu; Jackson C Ellen; McQueen Teresa; Monaco Giuseppe; Munsell Mark; Belmont John; Kantarjian Hagop; Sporn Michael B; Andreeff Michael
The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
Cancer research 2004;64(21):7927-35.
2004: Konopleva Marina; Elstner Elena; McQueen Teresa J; Tsao Twee; Sudarikov Andrey; Hu Wei; Schober Wendy D; Wang Rui-Yu; Chism David; Kornblau Steven M; Younes Anas; Collins Steven J; Koeffler H Phillip; Andreeff Michael
Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias.
Molecular cancer therapeutics 2004;3(10):1249-62.
2004: Monaco Giuseppe; Belmont John W; Konopleva Marina; Andreeff Michael; Tavor Sigal; Petit Isabelle; Kollet Orit; Lapidot Tsvee
Correlation between CXCR4 and homing or engraftment of acute myelogenous leukemia.
Cancer research 2004;64(18):6832 author reply 6832-3.
2004: Tabe Yoko; Konopleva Marina; Igari Jun; Andreeff Michael
Spontaneous migration of acute promyelocytic leukemia cells beneath cultured bone marrow adipocytes with matched expression of the major histocompatibility complex.
Rinsho byori. The Japanese journal of clinical pathology 2004;52(8):642-8.
2004: Munshi Anupama; Kurland John F; Nishikawa Takashi; Chiao Paul J; Andreeff Michael; Meyn Raymond E
Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells.
Molecular cancer therapeutics 2004;3(8):985-92.
2004: Zhang Chunlei; Ni Xiao; Konopleva Marina; Andreeff Michael; Duvic Madeleine
The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in Mycosis fungoides/Sézary syndrome cells.
The Journal of investigative dermatology 2004;123(2):380-7.
2004: Chen Jack S K; Konopleva Marina; Andreeff Michael; Multani Asha S; Pathak Sen; Mehta Kapil
Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis.
Journal of cellular physiology 2004;200(2):223-34.
2004: Tsimberidou Apostolia M; Keating Michael J; Giles Francis J; Wierda William G; Ferrajoli Alessandra; Lerner Susan; Beran Miloslav; Andreeff Michael; Kantarjian Hagop M; O'Brien Susan
Fludarabine and mitoxantrone for patients with chronic lymphocytic leukemia.
Cancer 2004;100(12):2583-91.
2004: Thomas Deborah A; Faderl Stefan; Cortes Jorge; O'Brien Susan; Giles Francis J; Kornblau Steven M; Garcia-Manero Guillermo; Keating Michael J; Andreeff Michael; Jeha Sima; Beran Miloslav; Verstovsek Srdan; Pierce Sherry; Letvak Laurie; Salvado August; Champlin Richard; Talpaz Moshe; Kantarjian Hagop
Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate.
Blood 2004;103(12):4396-407.
2004: Giles Francis; Thomas Deborah; Garcia-Manero Guillermo; Faderl Stefan; Cortes Jorge; Verstovsek Srdan; Ferrajoli Alessandra; Jeha Sima; Beran Miloslav; Koller Charles; Andreeff Michael; Cahill Ann; Clairmont Caroline; Sznol Mario; Kantarjian Hagop
A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(9):2908-17.
2004: Melichar Bohuslav; Konopleva Marina; Hu Wei; Melicharova Karolina; Andreeff Michael; Freedman Ralph S
Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression.
Gynecologic oncology 2004;93(1):149-54.
2004: Scappini Barbara; Gatto Simona; Onida Francesco; Ricci Clara; Divoky Vladimir; Wierda William G; Andreeff Michael; Dong Li; Hayes Kimberly; Verstovsek Srdan; Kantarjian Hagop M; Beran Miloslav
Changes associated with the development of resistance to imatinib (STI571) in two leukemia cell lines expressing p210 Bcr/Abl protein.
Cancer 2004;100(7):1459-71.
2004: Jiffar T; Kurinna S; Suck G; Carlson-Bremer D; Ricciardi M R; Konopleva M; Andreeff M; Ruvolo P P
PKC alpha mediates chemoresistance in acute lymphoblastic leukemia through effects on Bcl2 phosphorylation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(3):505-12.
2004: Tacke Frank; Marini Frank C; Zhao Shourong; McQueen Teresa; Konopleva Marina; Ruvolo Peter P; Hu Shi-Xue; Xu Hong-Ji; Andreeff Michael
Expression of inducible Bcl-X(S) in myeloid leukemia: compensatory upregulation of Bcl-X(L) and Bcl-2 prevents apoptosis and chemosensitization.
Cancer biology & therapy 2004;3(3):340-7.
2004: Hail Numsen; Konopleva Marina; Sporn Michael; Lotan Reuben; Andreeff Michael
Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO).
The Journal of biological chemistry 2004;279(12):11179-87.
2004: Norwood Kevin; Wang Rui-Yu; Hirschmann-Jax Charlotte; Andreeff Michael; Brenner Malcolm K; Goodell Margaret A; Wulf Gerald G
An in vivo propagated human acute myeloid leukemia expressing ABCA3.
Leukemia research 2004;28(3):295-9.
2004: Tabe Yoko; Konopleva Marina; Munsell Mark F; Marini Frank C; Zompetta Claudia; McQueen Teresa; Tsao Twee; Zhao Shourong; Pierce Sherry; Igari Jun; Estey Elihu H; Andreeff Michael
PML-RARalpha is associated with leptin-receptor induction: the role of mesenchymal stem cell-derived adipocytes in APL cell survival.
Blood 2004;103(5):1815-22.
2004: Zhao S; Konopleva M; Cabreira-Hansen M; Xie Z; Hu W; Milella M; Estrov Z; Mills G B; Andreeff M
Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(2):267-75.
2004: Andreeff M; Milella M; Carter B Z; Tabe Y; Ricciardi M R; Sneed T; Ruvolo P; Contractor R; Tsao T; Schober W; Evans R; McQueen T; Zeng Z; Kornblau S M; McCubrey J; Estey E; Mills G B; Reed J C; Konopleva M
Targeted therapy of AML new concepts.
Annals of hematology 2004;83 Suppl 1():S51-3.
2004: Monaco Giuseppe; Konopleva Marina; Munsell Mark; Leysath Clinton; Wang Rui-Yu; Jackson C Ellen; Korbling Martin; Estey Elihu; Belmont John; Andreeff Michael
Engraftment of acute myeloid leukemia in NOD/SCID mice is independent of CXCR4 and predicts poor patient survival.
Stem cells (Dayton, Ohio) 2004;22(2):188-201.
2003: Carter Bing Z; Kornblau Steven M; Tsao Twee; Wang Rui-Yu; Schober Wendy D; Milella Michele; Sung Hsi-Guang; Reed John C; Andreeff Michael
Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis.
Blood 2003;102(12):4179-86.
2003: Carter B Z; Milella M; Tsao T; McQueen T; Schober W D; Hu W; Dean N M; Steelman L; McCubrey J A; Andreeff M
Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(11):2081-9.
2003: Suh W-S; Kim Y S; Schimmer A D; Kitada S; Minden M; Andreeff M; Suh N; Sporn M; Reed J C
Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(11):2122-9.
2003: Pahler Jessica C; Ruiz Stacey; Niemer Irina; Calvert Leslie R; Andreeff Michael; Keating Michael; Faderl Stefan; McConkey David J
Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(12):4570-7.
2003: Lapillonne Helene; Konopleva Marina; Tsao Twee; Gold David; McQueen Teresa; Sutherland Robert L; Madden Timothy; Andreeff Michael
Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells.
Cancer research 2003;63(18):5926-39.
2003: Takahashi Satoshi; Mok Hoyin; Parrott M Brandon; Marini Frank C; Andreeff Michael; Brenner Malcolm K; Barry Michael A
Selection of chronic lymphocytic leukemia binding peptides.
Cancer research 2003;63(17):5213-7.
2003: Carter Bing Z; Wang Rui-Yu; Schober Wendy D; Milella Michele; Chism David; Andreeff Michael
Targeting Survivin expression induces cell proliferation defect and subsequent cell death involving mitochondrial pathway in myeloid leukemic cells.
Cell cycle (Georgetown, Tex.) 2003;2(5):488-93.
2003: O'Brien Susan; Giles Francis; Talpaz Moshe; Cortes Jorge; Rios Mary Beth; Shan Jianqin; Thomas Deborah; Andreeff Michael; Kornblau Steven; Faderl Stefan; Garcia-Manero Guillermo; White Kevin; Mallard Susie; Freireich Emil; Kantarjian Hagop M
Results of triple therapy with interferon-alpha, cytarabine, and homoharringtonine, and the impact of adding imatinib to the treatment sequence in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in early chronic phase.
Cancer 2003;98(5):888-93.
2003: Kantarjian Hagop M; O'Brien Susan; Cortes Jorge; Giles Francis J; Faderl Stefan; Issa Jean-Pierre; Garcia-Manero Guillermo; Rios Mary Beth; Shan Jianqin; Andreeff Michael; Keating Michael; Talpaz Moshe
Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia.
Cancer 2003;98(3):522-8.
2003: Yuan Jiuhong; Luo Robert Z; Fujii Satoshi; Wang Lin; Hu Wei; Andreeff Michael; Pan Yong; Kadota Mitsutaka; Oshimura Mitsuo; Sahin Aysegul A; Issa Jean-Pierre; Bast Robert C; Yu Yinhua
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.
Cancer research 2003;63(14):4174-80.
2003: Konopleva Marina; Cheng Su-Chun; Cortes Jorge E; Hayes Kimberly J; Pierce Sherry A; Andreeff Michael; Giles Francis J; O'Brien Susan; Kantarjian Hagop M; Estey Elihu H
Independent prognostic significance of day 21 cytogenetic findings in newly-diagnosed acute myeloid leukemia or refractory anemia with excess blasts.
Haematologica 2003;88(7):733-6.
2003: Milella Michele; Kornblau Steven M; Andreeff Michael
The mitogen-activated protein kinase signaling module as a therapeutic target in hematologic malignancies.
Reviews in clinical and experimental hematology 2003;7(2):160-90.
2003: Liepe K; Andreeff M; Mielcarek J; Barth I; Wunderlich G; Kropp J; Kotzerke J
[Beta-radiation exposure at the finger tips during the radionuclide synovectomy]
Nuklearmedizin. Nuclear medicine 2003;42(3):104-8.
2003: Faderl Stefan; Thomas Deborah A; O'Brien Susan; Garcia-Manero Guillermo; Kantarjian Hagop M; Giles Francis J; Koller Charles; Ferrajoli Alessandra; Verstovsek Srdan; Pro Barbara; Andreeff Michael; Beran Miloslav; Cortes Jorge; Wierda William; Tran Ngoc; Keating Michael J
Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies.
Blood 2003;101(9):3413-5.
2003: Biagi Ettore; Yvon Eric; Dotti Gianpietro; Amrolia Persis J; Takahashi Satoshi; Popat Uday; Marini Frank; Andreeff Michael; Brenner Malcolm K; Rousseau Raphaël F
Bystander transfer of functional human CD40 ligand from gene-modified fibroblasts to B-chronic lymphocytic leukemia cells.
Human gene therapy 2003;14(6):545-59.
2003: Schimmer Aaron D; Pedersen Irene Munk; Kitada Shinichi; Eksioglu-Demiralp Emel; Minden Mark D; Pinto Ryan; Mah Ken; Andreeff Michael; Kim Youngsoo; Suh Won Suk; Reed John C
Functional blocks in caspase activation pathways are common in leukemia and predict patient response to induction chemotherapy.
Cancer research 2003;63(6):1242-8.
2003: Cortes Jorge; Kantarjian Hagop; Albitar Maher; Thomas Deborah; Faderl Stefan; Koller Charles; Garcia-Manero Guillermo; Giles Francis; Andreeff Michael; O'Brien Susan; Keating Michael; Estey Elihu
A randomized trial of liposomal daunorubicin and cytarabine versus liposomal daunorubicin and topotecan with or without thalidomide as initial therapy for patients with poor prognosis acute myelogenous leukemia or myelodysplastic syndrome.
Cancer 2003;97(5):1234-41.
2002: Marini Frank C; Shayakhmetov Dmitry; Gharwan Helen; Lieber Andre; Andreeff Michael
Advances in gene transfer into haematopoietic stem cells by adenoviral vectors.
Expert opinion on biological therapy 2002;2(8):847-56.
2002: Bao Jia-Ju; Le Xiao-Feng; Wang Rui-Yu; Yuan Jiuhong; Wang Lin; Atkinson Edward N; LaPushin Ruth; Andreeff Michael; Fang Bingliang; Yu Yinhua; Bast Robert C
Reexpression of the tumor suppressor gene ARHI induces apoptosis in ovarian and breast cancer cells through a caspase-independent calpain-dependent pathway.
Cancer research 2002;62(24):7264-72.
2002: Guo J Q; Lin H; Kantarjian H; Talpaz M; Champlin R; Andreeff M; Glassman A; Arlinghaus R B
Comparison of competitive-nested PCR and real-time PCR in detecting BCR-ABL fusion transcripts in chronic myeloid leukemia patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(12):2447-53.
2002: Abbott Brian L; Colapietro Anne-Marie; Barnes Yuxiao; Marini Frank; Andreeff Michael; Sorrentino Brian P
Low levels of ABCG2 expression in adult AML blast samples.
Blood 2002;100(13):4594-601.
2002: Bondar Victor M; Sweeney-Gotsch Bridget; Andreeff Michael; Mills Gordon B; McConkey David J
Inhibition of the phosphatidylinositol 3'-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo.
Molecular cancer therapeutics 2002;1(12):989-97.
2002: Ueno Naoto T; Anagnostopoulos Athanasios; Rondón Gabriela; Champlin Richard E; Mikhailova N; Pankratova O S; Zoubarovskaya L S; Semenova E V; Afanasyev B V; O'Brien Susan; Andreeff Michael; Zaritskey Andrey Y
Successful non-myeloablative allogeneic transplantation for treatment of idiopathic hypereosinophilic syndrome.
British journal of haematology 2002;119(1):131-4.
2002: Pedersen Irene M; Kitada Shinichi; Schimmer Aaron; Kim Youngsoo; Zapata Juan M; Charboneau Lula; Rassenti Laura; Andreeff Michael; Bennett Frank; Sporn Michael B; Liotta Lance D; Kipps Thomas J; Reed John C
The triterpenoid CDDO induces apoptosis in refractory CLL B cells.
Blood 2002;100(8):2965-72.
2002: Tsimberidou Apostolia-Maria; Thomas Deborah; O'Brien Susan; Andreeff Michael; Kurzrock Razelle; Keating Michael; Albitar Maher; Kantarjian Hagop; Giles Francis
Recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein Enbrel in patients with refractory hematologic malignancies.
Cancer chemotherapy and pharmacology 2002;50(3):237-42.
2002: Konopleva M; Konoplev S; Hu W; Zaritskey A Y; Afanasiev B V; Andreeff M
Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(9):1713-24.
2002: Konopleva Marina; Zhao Shourong; Hu Wei; Jiang Shuwei; Snell Virginia; Weidner Douglas; Jackson C Ellen; Zhang Xin; Champlin Richard; Estey Elihu; Reed John C; Andreeff Michael
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells.
British journal of haematology 2002;118(2):521-34.
2002: Kantarjian Hagop M; Talpaz Moshe; O'Brien Susan; Smith Terry L; Giles Francis J; Faderl Stefan; Thomas Deborah A; Garcia-Manero Guillermo; Issa Jean-Pierre J; Andreeff Michael; Kornblau Steven M; Koller Charles; Beran Milosav; Keating Michael; Rios Mary Beth; Shan Jenny; Resta Debra; Capdeville Renaud; Hayes Kimberly; Albitar Maher; Freireich Emil J; Cortes Jorge E
Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: follow-up results.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2177-87.
2002: Cragg Louise H; Andreeff Michael; Feldman Eric; Roberts John; Murgo Anthony; Winning Mary; Tombes Mary Beth; Roboz Gail; Kramer Lora; Grant Steven
Phase I trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-B-D-arabinofuranosylcytosine in patients with refractory acute leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2123-33.
2002: Studeny Matus; Marini Frank C; Champlin Richard E; Zompetta Claudia; Fidler Isaiah J; Andreeff Michael
Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors.
Cancer research 2002;62(13):3603-8.
2002: Konopleva Marina; Andreeff Michael
Role of peroxisome proliferator-activated receptor-gamma in hematologic malignancies.
Current opinion in hematology 2002;9(4):294-302.
2002: Tacke Frank; Trautwein Christian; Zhao Shourong; Andreeff Michael; Manns Michael P; Ganser Arnold; Schöffski Patrick
Quantification of hepatic thrombopoietin mRNA transcripts in patients with chronic liver diseases shows maintained gene expression in different etiologies of liver cirrhosis.
Liver 2002;22(3):205-12.
2002: Lin Chung Wu; Manshouri Taghi; Jilani Iman; Neuberg Donna; Patel Kunal; Kantarjian Hagop; Andreeff Michael; Estrov Zeev; Beran Miloslav; Keating Michael; Estey Elihu; Albitar Maher
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Leukemia research 2002;26(6):551-9.
2002: Milella Michele; Estrov Zeev; Kornblau Steven M; Carter Bing Z; Konopleva Marina; Tari Ana; Schober Wendy D; Harris David; Leysath Clinton E; Lopez-Berestein Gabriel; Huang Ziwei; Andreeff Michael
Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia.
Blood 2002;99(9):3461-4.
2002: Tsimberidou Apostolia M; O'Brien Susan M; Cortes Jorge E; Faderl Stefan; Andreeff Michael; Kantarjian Hagop M; Keating Michael J; Giles Francis J
Phase II study of fludarabine, cytarabine (Ara-C), cyclophosphamide, cisplatin and GM-CSF (FACPGM) in patients with Richter's syndrome or refractory lymphoproliferative disorders.
Leukemia & lymphoma 2002;43(4):767-72.
2002: O'Brien Susan; Talpaz Moshe; Cortes Jorge; Shan Jianqin; Giles Francis J; Faderl Stefan; Thomas Deborah; Garcia-Manero Guillermo; Mallard Susie; Beth Mary; Koller Charles; Kornblau Steve; Andreeff Michael; Murgo Anthony; Keating Michael; Kantarjian Hagop M
Simultaneous homoharringtonine and interferon-alpha in the treatment of patients with chronic-phase chronic myelogenous leukemia.
Cancer 2002;94(7):2024-32.
2002: Lin H; Guo J Q; Andreeff M; Arlinghaus R B
Detection of dual TEL-ABL transcripts and a Tel-Abl protein containing phosphotyrosine in a chronic myeloid leukemia patient.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(2):294-7.
2002: Giles Francis J; Garcia-Manero Guillermo; Cortes Jorge E; Baker Sharyn D; Miller Carol B; O'Brien Susan M; Thomas Deborah A; Andreeff Michael; Bivins Carol; Jolivet Jacques; Kantarjian Hagop M
Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with refractory leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(3):656-64.
2002: Clodi Katharina; Asgari Zahra; Younes Mamoun; Palmer J Lynn; Cabanillas Fernando; Carbone Antonino; Andreeff Michael; Younes Anas
Expression of CD40 ligand (CD154) in B and T lymphocytes of Hodgkin disease: potential therapeutic significance.
Cancer 2002;94(1):1-5.
2002: Konopleva Marina; Tsao Twee; Ruvolo Peter; Stiouf Irina; Estrov Zeev; Leysath Clinton E; Zhao Shourong; Harris David; Chang Shirong; Jackson C Ellen; Munsell Mark; Suh Nanjoo; Gribble Gordon; Honda Tadashi; May W Stratford; Sporn Michael B; Andreeff Michael
Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
Blood 2002;99(1):326-35.
2002: Andreeff Michael; Konopleva Marina
Mechanisms of drug resistance in AML.
Cancer treatment and research 2002;112():237-62.
2001: Milella M; Kornblau S M; Estrov Z; Carter B Z; Lapillonne H; Harris D; Konopleva M; Zhao S; Estey E; Andreeff M
Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia.
The Journal of clinical investigation 2001;108(6):851-9.
2001: Wulf G G; Wang R Y; Kuehnle I; Weidner D; Marini F; Brenner M K; Andreeff M; Goodell M A
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia.
Blood 2001;98(4):1166-73.
2001: Bibawi S; Abi-Said D; Fayad L; Anderlini P; Ueno N T; Mehra R; Khouri I; Giralt S; Gajewski J; Donato M; Claxton D; Braunschweig I; van Besien K; Andreeff M; Andersson B S; Estey E H; Champlin R; Przepiorka D
Thiotepa, busulfan, and cyclophosphamide as a preparative regimen for allogeneic transplantation for advanced myelodysplastic syndrome and acute myelogenous leukemia.
American journal of hematology 2001;67(4):227-33.
2001: Ravandi F; Kantarjian H M; Talpaz M; O'Brien S; Faderl S; Giles F J; Thomas D; Cortes J; Andreeff M; Estrov Z; Rios M B; Albitar M
Expression of apoptosis proteins in chronic myelogenous leukemia: associations and significance.
Cancer 2001;91(11):1964-72.
2001: Carter B Z; Milella M; Altieri D C; Andreeff M
Cytokine-regulated expression of survivin in myeloid leukemia.
Blood 2001;97(9):2784-90.
2001: Takahashi S; Rousseau R F; Yotnda P; Mei Z; Dotti G; Rill D; Hurwitz R; Marini F; Andreeff M; Brenner M K
Autologous antileukemic immune response induced by chronic lymphocytic leukemia B cells expressing the CD40 ligand and interleukin 2 transgenes.
Human gene therapy 2001;12(6):659-70.
2001: Pachmann K; Zhao S; Schenk T; Kantarjian H; El-Naggar A K; Siciliano M J; Guo J Q; Arlinghaus R B; Andreeff M
Expression of bcr-abl mRNA in individual chronic myelogenous leukaemia cells as determined by in situ amplification.
British journal of haematology 2001;112(3):749-59.
2001: Giralt S; Thall P F; Khouri I; Wang X; Braunschweig I; Ippolitti C; Claxton D; Donato M; Bruton J; Cohen A; Davis M; Andersson B S; Anderlini P; Gajewski J; Kornblau S; Andreeff M; Przepiorka D; Ueno N T; Molldrem J; Champlin R
Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation.
Blood 2001;97(3):631-7.
2001: Körbling M; Giralt S; Khouri I; Mirza N; Donato M; Anderlini P; Fischer H; Andreeff M; McMannis J; Champlin R
Donor lymphocyte apheresis for adoptive immunotherapy compared with blood stem cell apheresis.
Journal of clinical apheresis 2001;16(2):82-7.
2000: Konopleva M; Tari A M; Estrov Z; Harris D; Xie Z; Zhao S; López-Berestein G; Andreeff M
Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins.
Blood 2000;95(12):3929-38.
2000: Tamm I; Kornblau S M; Segall H; Krajewski S; Welsh K; Kitada S; Scudiero D A; Tudor G; Qui Y H; Monks A; Andreeff M; Reed J C
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1796-803.
2000: Clodi K; Kliche K O; Zhao S; Weidner D; Schenk T; Consoli U; Jiang S; Snell V; Andreeff M
Cell-surface exposure of phosphatidylserine correlates with the stage of fludarabine-induced apoptosis in chronic lymphocytic leukemia and expression of apoptosis-regulating genes.
Cytometry 2000;40(1):19-25.
2000: Kornblau S M; Vu H T; Ruvolo P; Estrov Z; O'Brien S; Cortes J; Kantarjian H; Andreeff M; May W S
BAX and PKCalpha modulate the prognostic impact of BCL2 expression in acute myelogenous leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1401-9.
2000: Kantarjian H M; O'Brien S; Smith T L; Cortes J; Giles F J; Beran M; Pierce S; Huh Y; Andreeff M; Koller C; Ha C S; Keating M J; Murphy S; Freireich E J
Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(3):547-61.
2000: Ueno N T; Bartholomeusz C; Herrmann J L; Estrov Z; Shao R; Andreeff M; Price J; Paul R W; Anklesaria P; Yu D; Hung M C
E1A-mediated paclitaxel sensitization in HER-2/neu-overexpressing ovarian cancer SKOV3.ip1 through apoptosis involving the caspase-3 pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):250-9.
2000: Konopleva M; Rissling I; Andreeff M
CD38 in hematopoietic malignancies.
Chemical immunology 2000;75():189-206.
1999: Andreeff M; Jiang S; Zhang X; Konopleva M; Estrov Z; Snell V E; Xie Z; Okcu M F; Sanchez-Williams G; Dong J; Estey E H; Champlin R C; Kornblau S M; Reed J C; Zhao S
Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(11):1881-92.
1999: Beran M; Estey E; O'Brien S; Cortes J; Koller C A; Giles F J; Kornblau S; Andreeff M; Vey N; Pierce S R; Hayes K; Wong G C; Keating M; Kantarjian H
Topotecan and cytarabine is an active combination regimen in myelodysplastic syndromes and chronic myelomonocytic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(9):2819-30.
1999: Kitada S; Zapata J M; Andreeff M; Reed J C
Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia.
British journal of haematology 1999;106(4):995-1004.
1999: Zhao S; Asgary Z; Wang Y; Goodwin R; Andreeff M; Younes A
Functional expression of TRAIL by lymphoid and myeloid tumour cells.
British journal of haematology 1999;106(3):827-32.
1999: Kornblau S M; Thall P F; Estrov Z; Walterscheid M; Patel S; Theriault A; Keating M J; Kantarjian H; Estey E; Andreeff M
The prognostic impact of BCL2 protein expression in acute myelogenous leukemia varies with cytogenetics.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(7):1758-66.
1999: Marini F C; Snell V; Yu Q; Zhang X; Singletary S E; Champlin R; Andreeff M
Purging of contaminating breast cancer cells from hematopoietic stem cell grafts by adenoviral GAL-TEK gene therapy and magnetic antibody cell separation.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(6):1557-68.
1999: Aboul-Nasr R; Estey E H; Kantarjian H M; Freireich E J; Andreeff M; Johnson B J; Albitar M
Comparison of touch imprints with aspirate smears for evaluating bone marrow specimens.
American journal of clinical pathology 1999;111(6):753-8.
1999: Weinkauff R; Estey E H; Starostik P; Hayes K; Huh Y O; Hirsch-Ginsberg C; Andreeff M; Keating M; Kantarjian H M; Freireich E J; Albitar M
Use of peripheral blood blasts vs bone marrow blasts for diagnosis of acute leukemia.
American journal of clinical pathology 1999;111(6):733-40.
1999: O'Brien S; Kantarjian H; Koller C; Feldman E; Beran M; Andreeff M; Giralt S; Cheson B; Keating M; Freireich E; Rios M B; Talpaz M
Sequential homoharringtonine and interferon-alpha in the treatment of early chronic phase chronic myelogenous leukemia.
Blood 1999;93(12):4149-53.
1999: Sarris A H; Kliche K O; Pethambaram P; Preti A; Tucker S; Jackow C; Messina O; Pugh W; Hagemeister F B; McLaughlin P; Rodriguez M A; Romaguera J; Fritsche H; Witzig T; Duvic M; Andreeff M; Cabanillas F
Interleukin-10 levels are often elevated in serum of adults with Hodgkin's disease and are associated with inferior failure-free survival.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(4):433-40.
1999: Engel H; Drach J; Keyhani A; Jiang S; Van N T; Kimmel M; Sanchez-Williams G; Goodacre A; Andreeff M
Quantitation of minimal residual disease in acute myelogenous leukemia and myelodysplastic syndromes in complete remission by molecular cytogenetics of progenitor cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(4):568-77.
1999: Estey E H; Thall P F; Pierce S; Cortes J; Beran M; Kantarjian H; Keating M J; Andreeff M; Freireich E
Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin +/- all-trans retinoic acid +/- granulocyte colony-stimulating factor in poor prognosis newly diagnosed acute myeloid leukemia and myelodysplastic syndrome.
Blood 1999;93(8):2478-84.
1999: Konopleva M; Mikhail A; Estrov Z; Zhao S; Harris D; Sanchez-Williams G; Kornblau S M; Dong J; Kliche K O; Jiang S; Snodgrass H R; Estey E H; Andreeff M
Expression and function of leptin receptor isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and anti-apoptotic activities.
Blood 1999;93(5):1668-76.
1999: Kantarjian H M; O'Brien S; Smith T L; Rios M B; Cortes J; Beran M; Koller C; Giles F J; Andreeff M; Kornblau S; Giralt S; Keating M J; Talpaz M
Treatment of Philadelphia chromosome-positive early chronic phase chronic myelogenous leukemia with daily doses of interferon alpha and low-dose cytarabine.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(1):284-92.
1999: Bachier C R; Giles R E; Ellerson D; Hanania E G; Garcia-Sanchez F; Andreeff M; Cabanillas F; Champlin R; Choudhury R; Berenson R; Heimfeld S; Deisseroth A B
Hematopoietic retroviral gene marking in patients with follicular non-Hodgkin's lymphoma.
Leukemia & lymphoma 1999;32(3-4):279-88.
1999: Garderet L; Snell V; Przepiorka D; Schenk T; Lu J G; Marini F; Gluckman E; Andreeff M; Champlin R E
Effective depletion of alloreactive lymphocytes from peripheral blood mononuclear cell preparations.
Transplantation 1999;67(1):124-30.
1999: Ruan S; Okcu M F; Pong R C; Andreeff M; Levin V; Hsieh J T; Zhang W
Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):197-202.
1999: Konopleva M; Zhao S; Xie Z; Segall H; Younes A; Claxton D F; Estrov Z; Kornblau S M; Andreeff M
Apoptosis. Molecules and mechanisms.
Advances in experimental medicine and biology 1999;457():217-36.
1998: Chandra J; Niemer I; Gilbreath J; Kliche K O; Andreeff M; Freireich E J; Keating M; McConkey D J
Proteasome inhibitors induce apoptosis in glucocorticoid-resistant chronic lymphocytic leukemic lymphocytes.
Blood 1998;92(11):4220-9.
1998: Rahman Z; Kavanagh J; Champlin R; Giles R; Hanania E; Fu S; Zu Z; Mehra R; Holmes F; Kudelka A; Claxton D; Verschraegen C; Gajewski J; Andreeff M; Heimfeld S; Berenson R; Ellerson D; Calvert L; Mechetner E; Holzmayer T; Dayne A; Hamer J; Bachier C; Ostrove J; Deisseroth A
Chemotherapy immediately following autologous stem-cell transplantation in patients with advanced breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2717-21.
1998: Konopleva M; Estrov Z; Zhao S; Andreeff M; Mehta K
Ligation of cell surface CD38 protein with agonistic monoclonal antibody induces a cell growth signal in myeloid leukemia cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4702-8.
1998: Estrov Z; Thall P F; Talpaz M; Estey E H; Kantarjian H M; Andreeff M; Harris D; Van Q; Walterscheid M; Kornblau S M
Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia.
Blood 1998;92(9):3090-7.
1998: Clodi K; Asgary Z; Zhao S; Kliche K O; Cabanillas F; Andreeff M; Younes A
Coexpression of CD40 and CD40 ligand in B-cell lymphoma cells.
British journal of haematology 1998;103(1):270-5.
1998: Clodi K; Snell V; Zhao S; Cabanillas F; Andreeff M; Younes A
Unbalanced expression of Fas and CD40 in mantle cell lymphoma.
British journal of haematology 1998;103(1):217-9.
1998: Pagliaro L C; Liu B; Munker R; Andreeff M; Freireich E J; Scheinberg D A; Rosenblum M G
Humanized M195 monoclonal antibody conjugated to recombinant gelonin: an anti-CD33 immunotoxin with antileukemic activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1971-6.
1998: Kornblau S M; Andreeff M; Hu S X; Xu H J; Patel S; Theriault A; Koller C; Kantarjian H; Estey E; Deisseroth A B; Benedict W F
Low and maximally phosphorylated levels of the retinoblastoma protein confer poor prognosis in newly diagnosed acute myelogenous leukemia: a prospective study.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(8):1955-63.
1998: Kobayashi T; Ruan S; Jabbur J R; Consoli U; Clodi K; Shiku H; Owen-Schaub L B; Andreeff M; Reed J C; Zhang W
Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment.
Cell death and differentiation 1998;5(7):584-91.
1998: Schenk T M; Keyhani A; Bottcher S; Kliche K O; Goodacre A; Guo J Q; Arlinghaus R B; Kantarjian H M; Andreeff M
Multilineage involvement of Philadelphia chromosome positive acute lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(5):666-74.
1998: Ruan S; Okcu M F; Ren J P; Chiao P; Andreeff M; Levin V; Zhang W
Overexpressed WAF1/Cip1 renders glioblastoma cells resistant to chemotherapy agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin.
Cancer research 1998;58(7):1538-43.
1998: Kobayashi T; Ruan S; Clodi K; Kliche K O; Shiku H; Andreeff M; Zhang W
Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents.
Oncogene 1998;16(12):1587-91.
1998: Deng G; Lane C; Kornblau S; Goodacre A; Snell V; Andreeff M; Deisseroth A B
Ratio of bcl-xshort to bcl-xlong is different in good- and poor-prognosis subsets of acute myeloid leukemia.
Molecular medicine (Cambridge, Mass.) 1998;4(3):158-64.
1998: Ling Y H; Consoli U; Tornos C; Andreeff M; Perez-Soler R
Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol.
International journal of cancer. Journal international du cancer 1998;75(6):925-32.
1998: Lee H Y; Dohi D F; Kim Y H; Walsh G L; Consoli U; Andreeff M; Dawson M I; Hong W K; Kurie J M
All-trans retinoic acid converts E2F into a transcriptional suppressor and inhibits the growth of normal human bronchial epithelial cells through a retinoic acid receptor- dependent signaling pathway.
The Journal of clinical investigation 1998;101(5):1012-9.
1998: Consoli U; El-Tounsi I; Sandoval A; Snell V; Kleine H D; Brown W; Robinson J R; DiRaimondo F; Plunkett W; Andreeff M
Differential induction of apoptosis by fludarabine monophosphate in leukemic B and normal T cells in chronic lymphocytic leukemia.
Blood 1998;91(5):1742-8.
1998: Kornblau S M; Kantarjian H; O'Brien S; Andreeff M; Koller C A; Beran M; Keating M; Estey E
CECA-cyclophosphamide, etoposide, carboplatin and cytosine arabinoside--a new salvage regimen for relapsed or refractory acute myelogenous leukemia.
Leukemia & lymphoma 1998;28(3-4):371-5.
1998: Younes A; Snell V; Consoli U; Clodi K; Zhao S; Palmer J L; Thomas E K; Armitage R J; Andreeff M
Elevated levels of biologically active soluble CD40 ligand in the serum of patients with chronic lymphocytic leukaemia.
British journal of haematology 1998;100(1):135-41.
1998: Munker R; Kantarjian H; O'Brien S; Keating M; Andreeff M; Estey E H
Phase I study of taxol in refractory acute myelogenous leukemias using a weekly schedule.
Acta haematologica 1998;99(2):106-8.
1997: Consoli U; Van N T; Neamati N; Mahadevia R; Beran M; Zhao S; Andreeff M
Cellular pharmacology of mitoxantrone in p-glycoprotein-positive and -negative human myeloid leukemic cell lines.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(12):2066-74.
1997: Snell V; Clodi K; Zhao S; Goodwin R; Thomas E K; Morris S W; Kadin M E; Cabanillas F; Andreeff M; Younes A
Activity of TNF-related apoptosis-inducing ligand (TRAIL) in haematological malignancies.
British journal of haematology 1997;99(3):618-24.
1997: Munker R; Younes A; Cabanillas F; Andreeff M
Soluble CD95 in the serum of patients with low and intermediate grade malignant lymphomas: absence of prognostic correlations.
Leukemia & lymphoma 1997;27(5-6):517-21.
1997: Younes A; Consoli U; Snell V; Clodi K; Kliche K O; Palmer J L; Gruss H J; Armitage R; Thomas E K; Cabanillas F; Andreeff M
CD30 ligand in lymphoma patients with CD30+ tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(11):3355-62.
1997: Chandra J; Gilbreath J; Freireich E J; Kliche K O; Andreeff M; Keating M; McConkey D J
Protease activation is required for glucocorticoid-induced apoptosis in chronic lymphocytic leukemic lymphocytes.
Blood 1997;90(9):3673-81.
1997: Engel H; Goodacre A; Keyhani A; Jiang S; Van N T; Kimmel M; Sanchez-Williams G; Andreeff M
Minimal residual disease in acute myelogenous leukaemia and myelodysplastic syndromes: a follow-up of patients in clinical remission.
British journal of haematology 1997;99(1):64-75.
1997: Clodi K; Younes A; Goodacre A; Roberts M; Palmer J; Younes M; Cabanillas F; Andreeff M
Analysis of p53 gene deletions in patients with non-Hodgkin's lymphoma by dual-colour fluorescence in-situ hybridization.
British journal of haematology 1997;98(4):913-21.
1997: Hu G; Liu W; Mendelsohn J; Ellis L M; Radinsky R; Andreeff M; Deisseroth A B
Expression of epidermal growth factor receptor and human papillomavirus E6/E7 proteins in cervical carcinoma cells.
Journal of the National Cancer Institute 1997;89(17):1271-6.
1997: Konishi H; Steinbach G; Terry N H; Fujita K; Lee J J; Ruifrok A; Spaulding D; Lynch P M; Dubin J A; Andreeff M; Goodacre A M; Hattori T; Hittelman W N
S phase determination in intact colonic crypts by histone H3 messenger RNA in situ hybridization and confocal microscopy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(7):531-6.
1997: Rondón G; Giralt S; Pereira M; Van Besien K; Mehra R; Champlin R; Andreeff M
Analysis of chimerism following allogeneic bone marrow transplantation by fluorescent-in-situ hybridization.
Leukemia & lymphoma 1997;25(5-6):463-7.
1997: Kornblau S M; Estey E; Madden T; Tran H T; Zhao S; Consoli U; Snell V; Sanchez-Williams G; Kantarjian H; Keating M; Newman R A; Andreeff M
Phase I study of mitoxantrone plus etoposide with multidrug blockade by SDZ PSC-833 in relapsed or refractory acute myelogenous leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):1796-802.
1997: Mehta K; McQueen T; Manshouri T; Andreeff M; Collins S; Albitar M
Involvement of retinoic acid receptor-alpha-mediated signaling pathway in induction of CD38 cell-surface antigen.
Blood 1997;89(10):3607-14.
1997: Munker R; Marini F; Jiang S; Savary C; Owen-Schaub L; Andreeff M
Expression of CD95(FAS) by gene transfer does not sensitize K562 to Fas-killing.
Hematology and cell therapy 1997;39(2):75-8.
1997: Perez-Soler R; Neamati N; Zou Y; Schneider E; Doyle L A; Andreeff M; Priebe W; Ling Y H
Annamycin circumvents resistance mediated by the multidrug resistance-associated protein (MRP) in breast MCF-7 and small-cell lung UMCC-1 cancer cell lines selected for resistance to etoposide.
International journal of cancer. Journal international du cancer 1997;71(1):35-41.
1997: Choudhury A; Gajewski J L; Liang J C; Popat U; Claxton D F; Kliche K O; Andreeff M; Champlin R E
Use of leukemic dendritic cells for the generation of antileukemic cellular cytotoxicity against Philadelphia chromosome-positive chronic myelogenous leukemia.
Blood 1997;89(4):1133-42.
1997: Younes A; Zhao S; Zhang X; Snell V; Clodi K; Kliche K O; Thomas E; Cabanillas F; Andreeff M
CD30-ligand and CD40-ligand expression in lymph nodes involved with Hodgkin's disease.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8 Suppl 2():97-100.
1996: Lisovsky M; Estrov Z; Zhang X; Consoli U; Sanchez-Williams G; Snell V; Munker R; Goodacre A; Savchenko V; Andreeff M
Flt3 ligand stimulates proliferation and inhibits apoptosis of acute myeloid leukemia cells: regulation of Bcl-2 and Bax.
Blood 1996;88(10):3987-97.
1996: Tari A M; Andreeff M; Kleine H D; Lopez-Berestein G
Cellular uptake and localization of liposomal-methylphosphonate oligodeoxynucleotides.
Journal of molecular medicine (Berlin, Germany) 1996;74(10):623-8.
1996: Zhao S; Consoli U; Arceci R; Pfeifer J; Dalton W S; Andreeff M
Semi-automated PCR method for quantitating MDR1 expression.
BioTechniques 1996;21(4):726-31.
1996: Beran M; Kantarjian H; O'Brien S; Koller C; al-Bitar M; Arbuck S; Pierce S; Moore M; Abbruzzese J L; Andreeff M; Keating M; Estey E
Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia.
Blood 1996;88(7):2473-9.
1996: Munker R; Andreeff M
Induction of death (CD95/FAS), activation and adhesion (CD54) molecules on blast cells of acute myelogenous leukemias by TNF-alpha and IFN-gamma.
Cytokines and molecular therapy 1996;2(3):147-59.
1996: Rondón G; Giralt S; Huh Y; Khouri I; Andersson B; Andreeff M; Champlin R
Graft-versus-leukemia effect after allogeneic bone marrow transplantation for chronic lymphocytic leukemia.
Bone marrow transplantation 1996;18(3):669-72.
1996: Consoli U; Priebe W; Ling Y H; Mahadevia R; Griffin M; Zhao S; Perez-Soler R; Andreeff M
The novel anthracycline annamycin is not affected by P-glycoprotein-related multidrug resistance: comparison with idarubicin and doxorubicin in HL-60 leukemia cell lines.
Blood 1996;88(2):633-44.
1996: Younes A; Consoli U; Zhao S; Snell V; Thomas E; Gruss H J; Cabanillas F; Andreeff M
CD30 ligand is expressed on resting normal and malignant human B lymphocytes.
British journal of haematology 1996;93(3):569-71.
1996: Zhang W; Piatyszek M A; Kobayashi T; Estey E; Andreeff M; Deisseroth A B; Wright W E; Shay J W
Telomerase activity in human acute myelogenous leukemia: inhibition of telomerase activity by differentiation-inducing agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(5):799-803.
1996: Sarris A; Cortes J; Kantarjian H; Pierce S; Smith T; Keating M; Koller C; Kornblau S; O'Brien S; Andreeff M
Disseminated intravascular coagulation in adult acute lymphoblastic leukemia: frequent complications with fibrinogen levels less than 100 mg/dl.
Leukemia & lymphoma 1996;21(1-2):85-92.
1996: Escudier S M; Albitar M; Robertson L E; Andreeff M; Pierce S; Kantarjian H M
Acute lymphoblastic leukemia following preleukemic syndromes in adults.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(3):473-7.
1996: Younes A; Sarris A; Consoli U; Rodriguez A; McLaughlin P; Huh Y; Starry S; Cabanillas F; Andreeff M
A pilot study of high-dose interleukin-3 treatment of relapsed follicular small cleaved-cell lymphoma: hematologic, immunologic, and clinical results.
Blood 1996;87(5):1698-703.
1996: Mehta K; McQueen T; Neamati N; Collins S; Andreeff M
Activation of retinoid receptors RAR alpha and RXR alpha induces differentiation and apoptosis, respectively, in HL-60 cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(2):179-86.
1995: Kobayashi T; Consoli U; Andreeff M; Shiku H; Deisseroth A B; Zhang W
Activation of p21WAF1/Cip1 expression by a temperature-sensitive mutant of human p53 does not lead to apoptosis.
Oncogene 1995;11(11):2311-6.
1995: Preti H A; Huh Y O; O'Brien S M; Andreeff M; Pierce S T; Keating M; Kantarjian H M
Myeloid markers in adult acute lymphocytic leukemia. Correlations with patient and disease characteristics and with prognosis.
Cancer 1995;76(9):1564-70.
1995: Anderlini P; Benjamin R S; Wong F C; Kantarjian H M; Andreeff M; Kornblau S M; O'Brien S; Mackay B; Ewer M S; Pierce S A
Idarubicin cardiotoxicity: a retrospective study in acute myeloid leukemia and myelodysplasia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(11):2827-34.
1995: O'Brien S; Kantarjian H; Keating M; Beran M; Koller C; Robertson L E; Hester J; Rios M B; Andreeff M; Talpaz M
Homoharringtonine therapy induces responses in patients with chronic myelogenous leukemia in late chronic phase.
Blood 1995;86(9):3322-6.
1995: Del Giglio A; Drach J; Kornblau S M; Patel S; Novaes M; Khetan R; Sawaya N; Dorlhiac-Llacer P; Chamone D F; Andreeff M
Quantitative expression of proliferating cell nuclear antigen by western blot (PCNAWB) in peripheral blasts correlates with remission induction in patients with acute myelogenous leukemia.
Leukemia & lymphoma 1995;19(3-4):235-41.
1995: Kornblau S M; Thall P; Huh Y O; Estey E; Andreeff M
Analysis of CD7 expression in acute myelogenous leukemia: martingale residual plots combined with 'optimal' cutpoint analysis reveals absence of prognostic significance.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(10):1735-41.
1995: Körbling M; Huh Y O; Durett A; Mirza N; Miller P; Engel H; Anderlini P; van Besien K; Andreeff M; Przepiorka D; Deisseroth A B; Champlin R E
Allogeneic blood stem cell transplantation: peripheralization and yield of donor-derived primitive hematopoietic progenitor cells (CD34+ Thy-1dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host disease.
Blood 1995;86(7):2842-8.
1995: Vadhan-Raj S; Broxmeyer H E; Andreeff M; Bandres J C; Buescher E S; Benjamin R S; Papadopoulos N E; Burgess A; Patel S; Plager C; Hittelman W N; McAlister I; Garrison L; Williams D E
In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study.
Blood 1995;86(6):2098-105.
1995: Robertson L E; O'Brien S; Kantarjian H; Koller C; Beran M; Andreeff M; Lerner S; Plunkett W; Keating M J
A 3-day schedule of fludarabine in previously treated chronic lymphocytic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(9):1444-9.
1995: Estey E; Andreeff M
Phase II study of interleukin-6 in patients with smoldering relapse of acute myelogenous leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(9):1440-3.
1995: Whimbey E; Couch R B; Englund J A; Andreeff M; Goodrich J M; Raad I I; Lewis V; Mirza N; Luna M A; Baxter B
Respiratory syncytial virus pneumonia in hospitalized adult patients with leukemia.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;21(2):376-9.
1995: Hegewisch-Becker S; Hanania E G; Fu S; Körbling M; Deisseroth A B; Andreeff M
Transduction of MDR1 into human and mouse haemopoietic progenitor cells: use of rhodamine (Rh123) to determine transduction frequency and in vivo selection.
British journal of haematology 1995;90(4):876-83.
1995: Jendiroba D; Younes A; Katz R; Hill D; Cabanillas F; Andreeff M
Chromosome 17 numerical abnormalities in 55 patients with non-Hodgkin's lymphoma: a fluorescence in situ hybridization study.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(7):1144-6.
1995: Younes A; Jendiroba D; Katz R; Hill D; Cabanillas F; Andreeff M
Chromosome X numerical abnormalities in patients with non-Hodgkin's lymphoma. A study of 59 patients using fluorescence in situ hybridization.
Cancer genetics and cytogenetics 1995;82(1):23-9.
1995: Fu S; Consoli U; Hanania E G; Zu Z; Claxton D F; Andreeff M; Deisseroth A B
PML/RARalpha, a fusion protein in acute promyelocytic leukemia, prevents growth factor withdrawal-induced apoptosis in TF-1 cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(6):583-90.
1995: Drach D; Zhao S; Drach J; Andreeff M
Low incidence of MDR1 expression in acute promyelocytic leukaemia.
British journal of haematology 1995;90(2):369-74.
1995: Chang K S; Fan Y H; Andreeff M; Liu J; Mu Z M
The PML gene encodes a phosphoprotein associated with the nuclear matrix.
Blood 1995;85(12):3646-53.
1995: Robertson L E; O'Brien S; Kantarjian H; Koller C; Beran M; Andreeff M; Lerner S; Keating M J
Fludarabine plus doxorubicin in previously treated chronic lymphocytic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(6):943-5.
1995: Hanania E G; Fu S; Zu Z; Hegewisch-Becker S; Korbling M; Hester J; Durett A; Andreeff M; Mechetner E; Holzmayer T
Chemotherapy resistance to taxol in clonogenic progenitor cells following transduction of CD34 selected marrow and peripheral blood cells with a retrovirus that contains the MDR-1 chemotherapy resistance gene.
Gene therapy 1995;2(4):285-94.
1995: Younes A; Zhao S; Jendiroba D; Kleine H D; Cabanillas F; Andreeff M
Decreased expression of the deleted in colorectal carcinoma gene in non-Hodgkin's lymphoma.
Blood 1995;85(10):2813-6.
1995: Elting L S; Whimbey E; Lo W; Couch R; Andreeff M; Bodey G P
Epidemiology of influenza A virus infection in patients with acute or chronic leukemia.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 1995;3(3):198-202.
1995: Estey E H; Kantarjian H M; O'Brien S; Kornblau S; Andreeff M; Beran M; Pierce S; Keating M
High remission rate, short remission duration in patients with refractory anemia with excess blasts (RAEB) in transformation (RAEB-t) given acute myelogenous leukemia (AML)-type chemotherapy in combination with granulocyte-CSF (G-CSF).
Cytokines and molecular therapy 1995;1(1):21-8.
1995: Drach J; Zhao S; Drach D; Körbling M; Engel H; Andreeff M
Expression of MDR1 by normal bone marrow cells and its implication for leukemic hematopoiesis.
Leukemia & lymphoma 1995;16(5-6):419-24.
1995: Zhang W; Xu H J; Kornblau S M; Drach J; Hu S X; Andreeff M; Benedict W F; Deisseroth A B
Growth-factor stimulation reveals two mechanisms of retinoblastoma gene inactivation in human myelogenous leukemia cells.
Leukemia & lymphoma 1995;16(3-4):191-8.
1994: Drach D; Estrov Z; Zhao S; Drach J; Cork A; Collins D; Kantarjian H; Andreeff M
Granulocyte-colony stimulating factor, granulocyte-macrophage colony stimulating factor, PIXY-321, stem cell factor, interleukin-3, and interleukin-7: receptor binding and effects on clonogenic proliferation in acute lymphoblastic leukemia.
Leukemia & lymphoma 1994;16(1-2):79-88.
1994: Younes A; Jendiroba D; Engel H; Escudier S; Katz R; Rodriguez M A; Hill D; Cabanillas F; Andreeff M
High incidence of monosomy 18 in lymphoid malignancies that have bone marrow and peripheral blood involvement.
Cancer genetics and cytogenetics 1994;77(1):39-44.
1994: Anderlini P; Przepiorka D; Luna M; Langford L; Andreeff M; Claxton D; Deisseroth A B
Acanthamoeba meningoencephalitis after bone marrow transplantation.
Bone marrow transplantation 1994;14(3):459-61.
1994: Körbling M; Drach J; Champlin R E; Engel H; Huynh L; Kleine H D; Berenson R; Deisseroth A B; Andreeff M
Large-scale preparation of highly purified, frozen/thawed CD34+, HLA-DR- hematopoietic progenitor cells by sequential immunoadsorption (CEPRATE SC) and fluorescence-activated cell sorting: implications for gene transduction and/or transplantation.
Bone marrow transplantation 1994;13(5):649-54.
1994: Estey E; Thall P; Andreeff M; Beran M; Kantarjian H; O'Brien S; Escudier S; Robertson L E; Koller C; Kornblau S
Use of granulocyte colony-stimulating factor before, during, and after fludarabine plus cytarabine induction therapy of newly diagnosed acute myelogenous leukemia or myelodysplastic syndromes: comparison with fludarabine plus cytarabine without granulocyte colony-stimulating factor.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(4):671-8.
1994: Drach J; McQueen T; Engel H; Andreeff M; Robertson K A; Collins S J; Malavasi F; Mehta K
Retinoic acid-induced expression of CD38 antigen in myeloid cells is mediated through retinoic acid receptor-alpha.
Cancer research 1994;54(7):1746-52.
1994: Younes A; Pugh W; Goodacre A; Katz R; Rodriguez M A; Hill D; Cabanillas F; Andreeff M
Polysomy of chromosome 12 in 60 patients with non-Hodgkin's lymphoma assessed by fluorescence in situ hybridization: differences between follicular and diffuse large cell lymphoma.
Genes, chromosomes & cancer 1994;9(3):161-7.
1994: O'Brien S; Kantarjian H; Estey E; Koller C; Robertson B; Beran M; Andreeff M; Pierce S; Keating M
Lack of effect of 2-chlorodeoxyadenosine therapy in patients with chronic lymphocytic leukemia refractory to fludarabine therapy.
The New England journal of medicine 1994;330(5):319-22.
1993: Giralt S; Escudier S; Kantarjian H; Deisseroth A; Freireich E J; Andersson B S; O'Brien S; Andreeff M; Fisher H; Cork A
Preliminary results of treatment with filgrastim for relapse of leukemia and myelodysplasia after allogeneic bone marrow transplantation.
The New England journal of medicine 1993;329(11):757-61.
1993: Drach J; Lopez-Berestein G; McQueen T; Andreeff M; Mehta K
Induction of differentiation in myeloid leukemia cell lines and acute promyelocytic leukemia cells by liposomal all-trans-retinoic acid.
Cancer research 1993;53(9):2100-4.
1993: Escudier S M; Pereira-Leahy J M; Drach J W; Weier H U; Goodacre A M; Cork M A; Trujillo J M; Keating M J; Andreeff M
Fluorescent in situ hybridization and cytogenetic studies of trisomy 12 in chronic lymphocytic leukemia.
Blood 1993;81(10):2702-7.
1993: Deisseroth A B; Hanania E G; Fu S; Claxton D; Andreeff M; Champlin R; Kavanagh J; Hortobagyi G; Holmes F; Reading C
Genetic therapy of human neoplastic disease.
Journal of hematotherapy 1993;2(3):373-5.
1993: Estey E; Pierce S; Kantarjian H; O'Brien S; Beran M; Andreeff M; Escudier S; Koller C; Kornblau S; Robertson L
Treatment of myelodysplastic syndromes with AML-type chemotherapy.
Leukemia & lymphoma 1993;11 Suppl 2():59-63.
1992: Przepiorka D; Giralt S; Huh Y O; Andreeff M; Luna M; Reading C; Thomas M; Champlin R E
T-cell-depleted autologous marrow fails to prevent acute graft-versus-host disease after allogeneic marrow transplantation for lymphoblastic lymphoma.
Transplantation proceedings 1992;24(6):2906-7.
1992: Drach D; Zhao S; Drach J; Mahadevia R; Gattringer C; Huber H; Andreeff M
Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistant phenotype.
Blood 1992;80(11):2729-34.
1992: Kornblau S M; Xu H J; del Giglio A; Hu S X; Zhang W; Calvert L; Beran M; Estey E; Andreeff M; Trujillo J
Clinical implications of decreased retinoblastoma protein expression in acute myelogenous leukemia.
Cancer research 1992;52(17):4587-90.
1992: Estrov Z; Estey E H; Andreeff M; Talpaz M; Kurzrock R; Reading C L; Deisseroth A B; Gutterman J U
Comparison of in vivo and in vitro effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with acute myeloid leukemia.
Experimental hematology 1992;20(5):558-64.
1992: Zhang W; Hittelman W; Van N; Andreeff M; Deisseroth A
The phosphorylation of retinoblastoma gene product in human myeloid leukemia cells during the cell cycle.
Biochemical and biophysical research communications 1992;184(1):212-6.
1992: Zhang W; Drach J; Andreeff M; Deisseroth A
Proliferation of hematopoietic cells is accompanied by suppressed expression of heat shock protein 70.
Biochemical and biophysical research communications 1992;183(2):733-8.

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