FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Neil Fairweather

Research Profile

Chemicals & Drugs

Living Beings

Co-author Network

Publications

TOP 3
Lucía de la Riva; Edward W Tate; Stephanie E Willing; Neil Fairweather
Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile.
Nathan Scott; Omar Qazi; Michael J Wright; Neil Fairweather; Mahendra P Deonarain
Characterisation of a panel of anti-tetanus toxin single-chain Fvs reveals cooperative binding.
Keith Scott Robinson; Aurelie Mousnier; Cordula Hemrajani; Neil Fairweather; Cedric N Berger; Gad Frankel
The enteropathogenic Escherichia coli effector NleH inhibits apoptosis induced by Clostridium difficile toxin B.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Neil Fairweather (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: Lucía de la Riva; Edward W Tate; Stephanie E Willing; Neil Fairweather
Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile.
Journal of bacteriology 2011;193(13):3276-85.
2010: Nathan Scott; Omar Qazi; Michael J Wright; Neil Fairweather; Mahendra P Deonarain
Characterisation of a panel of anti-tetanus toxin single-chain Fvs reveals cooperative binding.
Molecular immunology 2010;47(10):1931-41.
2010: Keith Scott Robinson; Aurelie Mousnier; Cordula Hemrajani; Neil Fairweather; Cedric N Berger; Gad Frankel
The enteropathogenic Escherichia coli effector NleH inhibits apoptosis induced by Clostridium difficile toxin B.
Microbiology (Reading, England) 2010;156(Pt 6):1815-23.
2010: David Albesa-Jové; Thomas Bertrand; Elisabeth P Carpenter; Gemma V Swain; Jenson Lim; Jiancheng Zhang; Lesley F Haire; Nishi Vasisht; Veit Braun; Anton Lange; Christoph von Eichel-Streiber; Dmitri I Svergun; Neil Fairweather; Katherine A Brown
Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS.
Journal of molecular biology 2010;396(5):1260-70.
2010: Robert Fagan; Neil Fairweather
Dissecting the cell surface.
Methods in molecular biology (Clifton, N.J.) 2010;646():117-34.
2009: Jenny E Emerson; Catherine B Reynolds; Robert P Fagan; Helen A Shaw; David Goulding; Neil Fairweather
A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein.
Molecular microbiology 2009;74(3):541-56.
2009: Louise Johnston; Fatme Mawas; Robert Tierney; Omar Qazi; Neil Fairweather; Dorothea Sesardic
Transcutaneous delivery of tetanus toxin Hc fragment induces superior tetanus toxin neutralizing antibody response compared to tetanus toxoid.
Human vaccines 2009;5(4):230-6.
2009: Robert P Fagan; David Albesa-Jové; Omar Qazi; Dmitri I Svergun; Katherine A Brown; Neil Fairweather
Structural insights into the molecular organization of the S-layer from Clostridium difficile.
Molecular microbiology 2009;71(5):1308-22.
2009: Omar Qazi; Paul Hitchen; Bérangère Tissot; Maria Panico; Howard R Morris; Anne Dell; Neil Fairweather
Mass spectrometric analysis of the S-layer proteins from Clostridium difficile demonstrates the absence of glycosylation.
Journal of mass spectrometry : JMS 2009;44(3):368-74.
2008: Jenny E Emerson; Richard A Stabler; Brendan W Wren; Neil Fairweather
Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress.
Journal of medical microbiology 2008;57(Pt 6):757-64.
2008: Anne Wright; Denise Drudy; Lorraine Kyne; Katherine Brown; Neil Fairweather
Immunoreactive cell wall proteins of Clostridium difficile identified by human sera.
Journal of medical microbiology 2008;57(Pt 6):750-6.
2008: Alice Andreu; Neil Fairweather; Andrew D Miller
Clostridium neurotoxin fragments as potential targeting moieties for liposomal gene delivery to the CNS.
Chembiochem : a European journal of chemical biology 2008;9(2):219-31.
2008: Nathan Scott; Catherine B Reynolds; Michael J Wright; Omar Qazi; Neil Fairweather; Mahendra P Deonarain
Single-chain Fv phage display propensity exhibits strong positive correlation with overall expression levels.
BMC biotechnology 2008;8():97.
2007: Omar Qazi; Alan Brailsford; Anne Wright; Jeremy Faraar; Jim Campbell; Neil Fairweather
Identification and characterization of the surface-layer protein of Clostridium tetani.
FEMS microbiology letters 2007;274(1):126-31.
2007: Omar Qazi; Barbara Bolgiano; Dennis Crane; Dmitri I Svergun; Peter V Konarev; Zhong-Ping Yao; Carol V Robinson; Katherine A Brown; Neil Fairweather
The HC fragment of tetanus toxin forms stable, concentration-dependent dimers via an intermolecular disulphide bond.
Journal of molecular biology 2007;365(1):123-34.
2006: Omar Qazi; Dorothea Sesardic; Robert Tierney; Zahra Söderbäck; Dennis Crane; Barbara Bolgiano; Neil Fairweather
Reduction of the ganglioside binding activity of the tetanus toxin HC fragment destroys immunogenicity: implications for development of novel tetanus vaccines.
Infection and immunity 2006;74(8):4884-91.
2006: Paul S Fishman; Christopher Matthews; Deborah A Parks; Michael Box; Neil Fairweather
Immunization does not interfere with uptake and transport by motor neurons of the binding fragment of tetanus toxin.
Journal of neuroscience research 2006;83(8):1540-3.
2005: Anne Wright; Robin Wait; Shajna Begum; Ben Crossett; Judit Nagy; Katherine Brown; Neil Fairweather
Proteomic analysis of cell surface proteins from Clostridium difficile.
Proteomics 2005;5(9):2443-52.
2005: Karen Keith; Petra C F Oyston; Ben Crossett; Neil Fairweather; Richard Titball; Timothy R Walsh; Katherine A Brown
Functional characterization of OXA-57, a class D beta-lactamase from Burkholderia pseudomallei.
Antimicrobial agents and chemotherapy 2005;49(4):1639-41.
2005: John Tregoning; Simon Clare; Frances Bowe; Lorna Edwards; Neil Fairweather; Omar Qazi; Peter J Nixon; Pal Maliga; Gordon Dougan; Tracy Hussell
Protection against tetanus toxin using a plant-based vaccine.
European journal of immunology 2005;35(4):1320-6.
2004: Denise Drudy; Emanuela Calabi; Lorraine Kyne; Stavros Sougioultzis; Eoin Kelly; Neil Fairweather; Ciarán P Kelly
Human antibody response to surface layer proteins in Clostridium difficile infection.
FEMS immunology and medical microbiology 2004;41(3):237-42.
2003: Michael Box; Deborah A Parks; Andrew Knight; Christine Hale; Paul S Fishman; Neil Fairweather
A multi-domain protein system based on the HC fragment of tetanus toxin for targeting DNA to neuronal cells.
Journal of drug targeting 2003;11(6):333-43.
2003: Susan Foynes; Jane L Holley; Helen S Garmory; Richard Titball; Neil Fairweather
Vaccination against type F botulinum toxin using attenuated Salmonella enterica var Typhimurium strains expressing the BoNT/F H(C) fragment.
Vaccine 2003;21(11-12):1052-9.
2003: John Tregoning; Peter Nixon; Hiroshi Kuroda; Zora Svab; Simon Clare; Frances Bowe; Neil Fairweather; Jimmy Ytterberg; Klaas J van Wijk; Gordon Dougan; Pal Maliga
Expression of tetanus toxin Fragment C in tobacco chloroplasts.
Nucleic acids research 2003;31(4):1174-9.
2002: Emanuela Calabi; Franco Calabi; Alan D Phillips; Neil Fairweather
Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues.
Infection and immunity 2002;70(10):5770-8.
2002: Emanuela Calabi; Neil Fairweather
Patterns of sequence conservation in the S-Layer proteins and related sequences in Clostridium difficile.
Journal of bacteriology 2002;184(14):3886-97.
2001: Emanuela Calabi; S Ward; B Wren; Thanai Paxton; Maria Panico; Howard Morris; Anne Dell; Gordon Dougan; Neil Fairweather
Molecular characterization of the surface layer proteins from Clostridium difficile.
Molecular microbiology 2001;40(5):1187-99.
2000: Richard Stratford; G Douce; L Zhang-Barber; Neil Fairweather; J Eskola; Gordon Dougan
Influence of codon usage on the immunogenicity of a DNA vaccine against tetanus.
Vaccine 2000;19(7-8):810-5.
2000: Dayse Figueiredo; Christopher Matthews; Deborah A Parks; Neil Fairweather; Gordon Dougan; S G Wilt; Paul S Fishman
Interaction of tetanus toxin derived hybrid proteins with neuronal cells.
Journal of natural toxins 2000;9(4):363-79.
2000: Holm Schneider; M Groves; Christiane Mühle; P N Reynolds; Andrew Knight; Michael Themis; Jaime Carvajal; F Scaravilli; D T Curiel; Neil Fairweather; Charles Coutelle
Retargeting of adenoviral vectors to neurons using the Hc fragment of tetanus toxin.
Gene therapy 2000;7(18):1584-92.
2000: K Sinha; Michael Box; Giovanna Lalli; Giampietro Schiavo; Holm Schneider; M Groves; G Siligardi; Neil Fairweather
Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties.
Molecular microbiology 2000;37(5):1041-51.
2000: Christopher Matthews; Dayse Figueiredo; J B Wollack; Neil Fairweather; Gordon Dougan; R A Hallewell; J L Cadet; Paul S Fishman
Protective effect of supplemental superoxide dismutase on survival of neuronal cells during starvation. Requirement for cytosolic distribution.
Journal of molecular neuroscience : MN 2000;14(3):155-66.
1999: Andrew Knight; Jaime Carvajal; Holm Schneider; Charles Coutelle; Susan Chamberlain; Neil Fairweather
Non-viral neuronal gene delivery mediated by the HC fragment of tetanus toxin.
European journal of biochemistry / FEBS 1999;259(3):762-9.
1998: P Vaithanomsat; S Sangiambut; Derek Pickard; Neil Fairweather; Katherine A Brown
Construction of a Pseudomonas aeruginosa cosmid library.
Biochemical Society transactions 1998;26(3):S282.
1997: R Anderson; X M Gao; A Papakonstantinopoulou; Neil Fairweather; Mark Roberts; Gordon Dougan
Immunization of mice with DNA encoding fragment C of tetanus toxin.
Vaccine 1997;15(8):827-9.
1997: Dayse Figueiredo; R A Hallewell; L L Chen; Neil Fairweather; Gordon Dougan; Joseph M Savitt; Deborah A Parks; Paul S Fishman
Delivery of recombinant tetanus-superoxide dismutase proteins to central nervous system neurons by retrograde axonal transport.
Experimental neurology 1997;145(2 Pt 1):546-54.
1995: D Figueiredo; C Turcotte; Gad Frankel; Y Li; O Dolly; G Wilkin; D Marriott; Neil Fairweather; Gordon Dougan
Characterization of recombinant tetanus toxin derivatives suitable for vaccine development.
Infection and immunity 1995;63(8):3218-21.
1994: Ian G Charles; Neil Fairweather; Derek Pickard; J Beesley; R Anderson; Gordon Dougan; M Roberts
Expression of the Bordetella pertussis P.69 pertactin adhesin in Escherichia coli: fate of the carboxy-terminal domain.
Microbiology (Reading, England) 1994;140 ( Pt 12)():3301-8.
1994: C M Anjam Khan; B Villarreal-Ramos; R J Pierce; Gilles Riveau; Raquel Demarco de Hormaeche; H McNeill; T Ali; Neil Fairweather; Steven N Chatfield; André Capron
Construction, expression, and immunogenicity of the Schistosoma mansoni P28 glutathione S-transferase as a genetic fusion to tetanus toxin fragment C in a live Aro attenuated vaccine strain of Salmonella.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11261-5.
1994: Y Li; Patrick G Foran; Neil Fairweather; A de Paiva; U Weller; Gordon Dougan; J Oliver Dolly
A single mutation in the recombinant light chain of tetanus toxin abolishes its proteolytic activity and removes the toxicity seen after reconstitution with native heavy chain.
Biochemistry 1994;33(22):7014-20.
1994: A J Makoff; Ian G Charles; Neil Fairweather
Recombinant antigens as components of a diphtheria-tetanus-pertussis vaccine.
Bioprocess technology 1994;19():205-31.
1993: Ian G Charles; B Rodgers; S Musgrave; T C Peakman; A Chubb; Neil Fairweather; G Dougan; M Roberts
Expression of P.69/pertactin from Bordetella pertussis in a baculovirus/insect cell expression system: protective properties of the recombinant protein.
Research in microbiology 1993;144(9):681-90.
1993: Neil Fairweather; D Sanders; D Slater; M Hudel; E Habermann; U Weller
Production of biologically active light chain of tetanus toxin in Escherichia coli. Evidence for the importance of the C-terminal 16 amino acids for full biological activity.
FEBS letters 1993;323(3):218-22.
1992: R Strugnell; Gordon Dougan; Steven N Chatfield; Ian G Charles; Neil Fairweather; John Tite; J L Li; J Beesley; M Roberts
Characterization of a Salmonella typhimurium aro vaccine strain expressing the P.69 antigen of Bordetella pertussis.
Infection and immunity 1992;60(10):3994-4002.
1992: J Li; Neil Fairweather; P Novotny; Gordon Dougan; Ian G Charles
Cloning, nucleotide sequence and heterologous expression of the protective outer-membrane protein P.68 pertactin from Bordetella bronchiseptica.
Journal of general microbiology 1992;138 Pt 8():1697-705.
1992: Steven N Chatfield; Ian G Charles; A J Makoff; M D Oxer; Gordon Dougan; Derek Pickard; D Slater; Neil Fairweather
Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccine.
Bio/technology (Nature Publishing Company) 1992;10(8):888-92.
1992: M Roberts; John Tite; Neil Fairweather; Gordon Dougan; Ian G Charles
Recombinant P.69/pertactin: immunogenicity and protection of mice against Bordetella pertussis infection.
Vaccine 1992;10(1):43-8.
1992: Steven N Chatfield; Neil Fairweather; Ian G Charles; Derek Pickard; Myron M Levine; David Hone; M Posada; R A Strugnell; Gordon Dougan
Construction of a genetically defined Salmonella typhi Ty2 aroA, aroC mutant for the engineering of a candidate oral typhoid-tetanus vaccine.
Vaccine 1992;10(1):53-60.
1991: Mike Romanos; J J Clare; K M Beesley; F B Rayment; S P Ballantine; A J Makoff; Gordon Dougan; Neil Fairweather; Ian G Charles
Recombinant Bordetella pertussis pertactin (P69) from the yeast Pichia pastoris: high-level production and immunological properties.
Vaccine 1991;9(12):901-6.
1991: M Roberts; Neil Fairweather; E Leininger; Derek Pickard; E L Hewlett; A Robinson; C Hayward; Gordon Dougan; Ian G Charles
Construction and characterization of Bordetella pertussis mutants lacking the vir-regulated P.69 outer membrane protein.
Molecular microbiology 1991;5(6):1393-404.
1991: M Lipscombe; Ian G Charles; M Roberts; Gordon Dougan; John Tite; Neil Fairweather
Intranasal immunization using the B subunit of the Escherichia coli heat-labile toxin fused to an epitope of the Bordetella pertussis P.69 antigen.
Molecular microbiology 1991;5(6):1385-92.
1991: Ian G Charles; B C Rodgers; A J Makoff; Steven N Chatfield; D E Slater; Neil Fairweather
Synthesis of tetanus toxin fragment C in insect cells by use of a baculovirus expression system.
Infection and immunity 1991;59(5):1627-32.
1991: Mike Romanos; A J Makoff; Neil Fairweather; K M Beesley; D E Slater; F B Rayment; M M Payne; J J Clare
Expression of tetanus toxin fragment C in yeast: gene synthesis is required to eliminate fortuitous polyadenylation sites in AT-rich DNA.
Nucleic acids research 1991;19(7):1461-7.
1991: E Leininger; M Roberts; J G Kenimer; Ian G Charles; Neil Fairweather; P Novotny; Michael J Brennan
Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):345-9.
1991: S Servos; Steven N Chatfield; David Hone; Myron M Levine; G Dimitriadis; Derek Pickard; Gordon Dougan; Neil Fairweather; Ian G Charles
Molecular cloning and characterization of the aroD gene encoding 3-dehydroquinase from Salmonella typhi.
Journal of general microbiology 1991;137(1):147-52.
1990: A J Makoff; M D Oxer; S P Ballantine; Neil Fairweather; Ian G Charles
Protective surface antigen P69 of Bordetella pertussis: its characterization and very high level expression in Escherichia coli.
Bio/technology (Nature Publishing Company) 1990;8(11):1030-3.
1990: Gordon Dougan; Steven N Chatfield; M Roberts; Ian G Charles; S Comerford; L J Li; Neil Fairweather
Bacterial pathogens--a route to oral drug delivery.
Biochemical Society transactions 1990;18(5):746-8.
1990: Neil Fairweather; Steven N Chatfield; Ian G Charles; M Roberts; M Lipscombe; L J Li; D Strugnell; S Comerford; John Tite; Gordon Dougan
Use of live attenuated bacteria to stimulate immunity.
Research in microbiology 1990;141(7-8):769-73.
1990: Neil Fairweather; Steven N Chatfield; A J Makoff; R A Strugnell; J Bester; Duncan J Maskell; Gordon Dougan
Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier.
Infection and immunity 1990;58(5):1323-6.
1990: R A Strugnell; Duncan J Maskell; Neil Fairweather; Derek Pickard; Alan Cockayne; C Penn; Gordon Dougan
Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains.
Gene 1990;88(1):57-63.
1989: A J Makoff; M D Oxer; Mike Romanos; Neil Fairweather; S Ballantine
Expression of tetanus toxin fragment C in E. coli: high level expression by removing rare codons.
Nucleic acids research 1989;17(24):10191-202.
1989: Ian G Charles; Gordon Dougan; Derek Pickard; Steven N Chatfield; M Smith; P Novotny; P Morrissey; Neil Fairweather
Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3554-8.
1989: D Leslie; Neil Fairweather; Derek Pickard; Gordon Dougan; M Kehoe
Phospholipase C and haemolytic activities of Clostridium perfringens alpha-toxin cloned in Escherichia coli: sequence and homology with a Bacillus cereus phospholipase C.
Molecular microbiology 1989;3(3):383-92.
1988: Ian G Charles; Gordon Dougan; Derek Pickard; S Charfield; M Smith; P Novotny; Neil Fairweather
Molecular cloning and analysis of P. 69, a vir-controlled protein from Bordetella pertussis.
The Tokai journal of experimental and clinical medicine 1988;13 Suppl():227-34.
1987: Neil Fairweather; V A Lyness; Duncan J Maskell
Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli.
Infection and immunity 1987;55(11):2541-5.
1986: Neil Fairweather; V A Lyness
The complete nucleotide sequence of tetanus toxin.
Nucleic acids research 1986;14(19):7809-12.
1986: Neil Fairweather; V A Lyness; Derek Pickard; G Allen; R O Thomson
Cloning, nucleotide sequencing, and expression of tetanus toxin fragment C in Escherichia coli.
Journal of bacteriology 1986;165(1):21-7.
1986: Duncan J Maskell; K Sweeney; D O'Callaghan; Foo Y Liew; Neil Fairweather; Gordon Dougan
Attenuated salmonellae as vaccines and carriers of foreign antigens.
Annali Sclavo. Collana monografica 1986;3(1-2):133-41.
1983: Neil Fairweather; S Kennedy; T J Foster; M Kehoe; G Dougan
Expression of a cloned Staphylococcus aureus alpha-hemolysin determinant in Bacillus subtilis and Staphylococcus aureus.
Infection and immunity 1983;41(3):1112-7.
1983: M Kehoe; J Duncan; T Foster; Neil Fairweather; G Dougan
Cloning, expression, and mapping of the Staphylococcus aureus alpha-hemolysin determinant in Escherichia coli K-12.
Infection and immunity 1983;41(3):1105-11.