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Falko Falkner

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Publications

TOP 3
Walter Wodal; Christina Piskernik; Daniel Portsmouth; Helga Savidis-Dacho; P Noel Barrett; Sogue Coulibaly; Falko G Falkner; Richard Fritz; Claudia Gaiswinkler; Christine Hohenadl; M Keith Howard; A Kerschbaum; Stefan Kiermayr; Otfried Kistner; Thomas R Kreil
A cell culture-derived whole-virus H9N2 vaccine induces high titer antibodies against hemagglutinin and neuraminidase and protects mice from severe lung pathology and weight loss after challenge with a highly virulent H9N2 isolate.
Klaus K Orlinger; Yvonne Hofmeister; Richard Fritz; Georg W Holzer; Falko G Falkner; Bernd Unger; Alexandra Loew-Baselli; Eva Maria Poellabauer; Hartmut J Ehrlich; P Noel Barrett; Thomas R Kreil
A tick-borne encephalitis virus vaccine based on the European prototype strain induces broadly reactive cross-neutralizing antibodies in humans.
Georg W Holzer; Sogue Coulibaly; Gerald Aichinger; Helga Savidis-Dacho; Josef Mayrhofer; Susanne Brunner; Karl Schmid; Otfried Kistner; John Aaskov; Falko G Falkner; Hartmut Ehrlich; P Noel Barrett; Thomas R Kreil
Evaluation of an inactivated Ross River virus vaccine in active and passive mouse immunization models and establishment of a correlate of protection.

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All Publications

2012: Walter Wodal; Christina Piskernik; Daniel Portsmouth; Helga Savidis-Dacho; P Noel Barrett; Sogue Coulibaly; Falko G Falkner; Richard Fritz; Claudia Gaiswinkler; Christine Hohenadl; M Keith Howard; A Kerschbaum; Stefan Kiermayr; Otfried Kistner; Thomas R Kreil
A cell culture-derived whole-virus H9N2 vaccine induces high titer antibodies against hemagglutinin and neuraminidase and protects mice from severe lung pathology and weight loss after challenge with a highly virulent H9N2 isolate.
Vaccine 2012;30(31):4625-31.
2011: Klaus K Orlinger; Yvonne Hofmeister; Richard Fritz; Georg W Holzer; Falko G Falkner; Bernd Unger; Alexandra Loew-Baselli; Eva Maria Poellabauer; Hartmut J Ehrlich; P Noel Barrett; Thomas R Kreil
A tick-borne encephalitis virus vaccine based on the European prototype strain induces broadly reactive cross-neutralizing antibodies in humans.
The Journal of infectious diseases 2011;203(11):1556-64.
2011: Georg W Holzer; Sogue Coulibaly; Gerald Aichinger; Helga Savidis-Dacho; Josef Mayrhofer; Susanne Brunner; Karl Schmid; Otfried Kistner; John Aaskov; Falko G Falkner; Hartmut Ehrlich; P Noel Barrett; Thomas R Kreil
Evaluation of an inactivated Ross River virus vaccine in active and passive mouse immunization models and establishment of a correlate of protection.
Vaccine 2011;29(24):4132-41.
2011: Patricia S Ricci; Birgit Schäfer; Falko G Falkner; Thomas R Kreil; Georg W Holzer
Selection of recombinant MVA by rescue of the essential D4R gene.
Virology journal 2011;8():529.
2011: Birgit Schäfer; Michael Schwendinger; Georg W Holzer; Alexandra Joachimsthaler; Thomas R Kreil; P Noel Barrett; Sogue Coulibaly; Brian A Crowe; Falko G Falkner
Pre-clinical efficacy and safety of experimental vaccines based on non-replicating vaccinia vectors against yellow fever.
PloS one 2011;6(9):e24505.
2011: Annett Hessel; Michael Schwendinger; Georg W Holzer; Klaus K Orlinger; Sogue Coulibaly; Helga Savidis-Dacho; Marie-Luise Zips; Brian A Crowe; Thomas R Kreil; Hartmut J Ehrlich; P Noel Barrett; Falko G Falkner
Vectors based on modified vaccinia Ankara expressing influenza H5N1 hemagglutinin induce substantial cross-clade protective immunity.
PloS one 2011;6(1):e16247.
2010: Klaus K Orlinger; Georg W Holzer; Julia Schwaiger; Josef Mayrhofer; Karl Schmid; Otfried Kistner; P Noel Barrett; Falko G Falkner
An inactivated West Nile Virus vaccine derived from a chemically synthesized cDNA system.
Vaccine 2010;28(19):3318-24.
2010: Annett Hessel; Michael Schwendinger; Daniela Fritz; Sogue Coulibaly; Georg W Holzer; Nicolas Sabarth; Otfried Kistner; Walter Wodal; Astrid Kerschbaum; Helga Savidis-Dacho; Brian A Crowe; Thomas R Kreil; P Noel Barrett; Falko G Falkner
A pandemic influenza H1N1 live vaccine based on modified vaccinia Ankara is highly immunogenic and protects mice in active and passive immunizations.
PloS one 2010;5(8):e12217.
2010: Otfried Kistner; Brian A Crowe; Walter Wodal; Astrid Kerschbaum; Helga Savidis-Dacho; Nicolas Sabarth; Falko G Falkner; Ines Mayerhofer; Wolfgang Mundt; Manfred Reiter; Leopold Grillberger; Christa Tauer; Michael Graninger; Alois Sachslehner; Michael Schwendinger; Peter Brühl; Thomas R Kreil; Hartmut J Ehrlich; P Noel Barrett
A whole virus pandemic influenza H1N1 vaccine is highly immunogenic and protective in active immunization and passive protection mouse models.
PloS one 2010;5(2):e9349.
2009: Josef Mayrhofer; Sogue Coulibaly; Annett Hessel; Georg W Holzer; Michael Schwendinger; Peter Brühl; Marijan Gerencer; Brian A Crowe; Shen Shuo; Wanjing Hong; Yee-Joo Tan; Barbara Dietrich; Nicolas Sabarth; Helga Savidis-Dacho; Otfried Kistner; P Noel Barrett; Falko G Falkner
Nonreplicating vaccinia virus vectors expressing the H5 influenza virus hemagglutinin produced in modified Vero cells induce robust protection.
Journal of virology 2009;83(10):5192-203.
2007: Otfried Kistner; M Keith Howard; Martin Spruth; Walter Wodal; Peter Brühl; Marijan Gerencer; Brian A Crowe; Helga Savidis-Dacho; Ian Livey; Manfred Reiter; Ines Mayerhofer; Christa Tauer; Leopold Grillberger; Wolfgang Mundt; Falko G Falkner; P Noel Barrett
Cell culture (Vero) derived whole virus (H5N1) vaccine based on wild-type virus strain induces cross-protective immune responses.
Vaccine 2007;25(32):6028-36.
2006: Kuo-Ming Lip; Shuo Shen; Xiaoming Yang; Choong-Tat Keng; Aihua Zhang; Hsueh-Ling Janice Oh; Zhi-Hong Li; Le-Ann Hwang; Chih-Fong Chou; Burtram Clintom Fielding; Timothy H P Tan; Josef Mayrhofer; Falko G Falkner; Jianlin Fu; Seng Gee Lim; Wanjin Hong; Yee-Joo Tan
Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.
Journal of virology 2006;80(2):941-50.
2005: S Coulibaly; Peter Brühl; Josef Mayrhofer; K Schmid; Marijan Gerencer; Falko G Falkner
The nonreplicating smallpox candidate vaccines defective vaccinia Lister (dVV-L) and modified vaccinia Ankara (MVA) elicit robust long-term protection.
Virology 2005;341(1):91-101.
2005: Georg W Holzer; Josef Mayrhofer; Werner Gritschenberger; Falko G Falkner
Dominant negative selection of vaccinia virus using a thymidine kinase/thymidylate kinase fusion gene and the prodrug azidothymidine.
Virology 2005;337(2):235-41.
2004: Falko G Falkner; Georg W Holzer
Vaccinia viral/retroviral chimeric vectors.
Current gene therapy 2004;4(4):417-26.
2003: Christian Konetschny; Georg W Holzer; Carsten Urban; Thomas Hämmerle; Josef Mayrhofer; Falko G Falkner
Generation of transduction-competent retroviral vectors by infection with a single hybrid vaccinia virus.
Journal of virology 2003;77(12):7017-25.
2003: Georg W Holzer; Josef Mayrhofer; Judith Leitner; Martin Blum; Gerald Webersinke; Sabine Heuritsch; Falko G Falkner
Overexpression of hepatitis B virus surface antigens including the preS1 region in a serum-free Chinese hamster ovary cell line.
Protein expression and purification 2003;29(1):58-69.
2003: Georg W Holzer; Falko G Falkner
Poxviral/retroviral chimeric vectors allow cytoplasmic production of transducing defective retroviral particles.
Methods in molecular medicine 2003;76():565-78.
2002: B T Ober; Peter Brühl; M Schmidt; V Wieser; Werner Gritschenberger; S Coulibaly; Helga Savidis-Dacho; Marijan Gerencer; Falko G Falkner
Immunogenicity and safety of defective vaccinia virus lister: comparison with modified vaccinia virus Ankara.
Journal of virology 2002;76(15):7713-23.
2002: Christian Konetschny; Georg W Holzer; Falko G Falkner
Retroviral vectors produced in the cytoplasmic vaccinia virus system transduce intron-containing genes.
Journal of virology 2002;76(3):1236-43.
2001: F Gruber; Falko G Falkner; Friedrich Dorner; Thomas Hämmerle
Quantitation of viral DNA by real-time PCR applying duplex amplification, internal standardization, and two-color fluorescence detection.
Applied and environmental microbiology 2001;67(6):2837-9.
2000: Carsten Urban; F Gruber; Michael Kundi; Falko G Falkner; Friedrich Dorner; Thomas Hämmerle
A systematic and quantitative analysis of PCR template contamination.
Journal of forensic sciences 2000;45(6):1307-11.
2000: Michèle Himmelspach; M Pfleiderer; B E Fischer; Barbara Plaimauer; Gerhard Antoine; Falko G Falkner; Friedrich Dorner; Uwe Schlokat
Recombinant human factor X: high yield expression and the role of furin in proteolytic maturation in vivo and in vitro.
Thrombosis research 2000;97(2):51-67.
1999: Georg W Holzer; G Remp; Gerhard Antoine; M Pfleiderer; O M Enzersberger; W Emsenhuber; Thomas Hämmerle; F Gruber; Carsten Urban; Falko G Falkner; Friedrich Dorner
Highly efficient induction of protective immunity by a vaccinia virus vector defective in late gene expression.
Journal of virology 1999;73(6):4536-42.
1999: Georg W Holzer; Josef Mayrhofer; Werner Gritschenberger; Friedrich Dorner; Falko G Falkner
Poxviral/retroviral chimeric vectors allow cytoplasmic production of transducing defective retroviral particles.
Virology 1999;253(1):107-14.
1998: M Himly; M Pfleiderer; Georg W Holzer; U Fischer; E Hannak; Falko G Falkner; Friedrich Dorner
Defective vaccinia virus as a biologically safe tool for the overproduction of recombinant human secretory proteins.
Protein expression and purification 1998;14(3):317-26.
1998: Georg W Holzer; Werner Gritschenberger; Josef Mayrhofer; V Wieser; Friedrich Dorner; Falko G Falkner
Dominant host range selection of vaccinia recombinants by rescue of an essential gene.
Virology 1998;249(1):160-6.
1998: F Gruber; Falko G Falkner; Friedrich Dorner; Thomas Hämmerle
Precise quantitation of human parvovirus B19 DNA in biological samples by PCR.
Biologicals : journal of the International Association of Biological Standardization 1998;26(3):213-6.
1998: W Kim; Yao Tang; Y Okada; Ted A Torrey; Sisir K Chattopadhyay; M Pfleiderer; Falko G Falkner; Friedrich Dorner; W Choi; N Hirokawa; Herbert C Morse
Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.
Journal of virology 1998;72(8):6898-901.
1998: S E Herlitschka; Uwe Schlokat; Falko G Falkner; Friedrich Dorner
High expression of a B-domain deleted factor VIII gene in a human hepatic cell line.
Journal of biotechnology 1998;61(3):165-73.
1998: Gerhard Antoine; Friedrich Scheiflinger; Friedrich Dorner; Falko G Falkner
The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses.
Virology 1998;244(2):365-96.
1998: Friedrich Scheiflinger; Friedrich Dorner; Falko G Falkner
Transient marker stabilisation: a general procedure to construct marker-free recombinant vaccinia virus.
Archives of virology 1998;143(3):467-74.
1997: Georg W Holzer; Falko G Falkner
Construction of a vaccinia virus deficient in the essential DNA repair enzyme uracil DNA glycosylase by a complementing cell line.
Journal of virology 1997;71(7):4997-5002.
1997: Friedrich Scheiflinger; Falko G Falkner; Friedrich Dorner
Role of the fowlpox virus thymidine kinase gene for the growth of FPV recombinants in cell culture.
Archives of virology 1997;142(12):2421-31.
1997: Thomas Hämmerle; Michèle Himmelspach; Friedrich Dorner; Falko G Falkner
A sensitive PCR assay system for the quantitation of viral genome equivalents: human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV).
Archives of virology 1997;142(7):1297-306.
1996: Michèle Himmelspach; F Gruber; Gerhard Antoine; Falko G Falkner; Friedrich Dorner; Thomas Hämmerle
Specific quantitation of genomic DNA in the femtogram range by amplification of repetitive sequences.
Analytical biochemistry 1996;242(2):240-7.
1996: S E Herlitschka; Falko G Falkner; Uwe Schlokat; Friedrich Dorner
Overexpression of human prothrombin in permanent cell lines using a dominant selection/amplification fusion marker.
Protein expression and purification 1996;8(3):358-64.
1996: Gerhard Antoine; Friedrich Scheiflinger; Georg W Holzer; T Langmann; Falko G Falkner; Friedrich Dorner
Characterization of the vaccinia MVA hemagglutinin gene locus and its evaluation as an insertion site for foreign genes.
Gene 1996;177(1-2):43-6.
1996: M Pfleiderer; Falko G Falkner; Friedrich Dorner
Deletion of the myristylation signal allows high-level production of the hepatitis B virus large surface glycoprotein preS1 with vaccinia virus recombinants.
Gene 1996;176(1-2):131-7.
1996: Thomas Hämmerle; Falko G Falkner; Friedrich Dorner
A sensitive PCR assay system for the quantitation of viral genome equivalents: hepatitis C virus (HCV).
Archives of virology 1996;141(11):2103-14.
1996: Friedrich Scheiflinger; Falko G Falkner; Friedrich Dorner
Evaluation of the thymidine kinase (tk) locus as an insertion site in the highly attenuated vaccinia MVA strain.
Archives of virology 1996;141(3-4):663-9.
1995: M Pfleiderer; Falko G Falkner; Friedrich Dorner
A novel vaccinia virus expression system allowing construction of recombinants without the need for selection markers, plasmids and bacterial hosts.
The Journal of general virology 1995;76 ( Pt 12)():2957-62.
1995: M Pfleiderer; Falko G Falkner; Friedrich Dorner
Requirements for optimal expression of secreted and nonsecreted recombinant proteins in vaccinia virus systems.
Protein expression and purification 1995;6(5):559-69.
1992: Friedrich Scheiflinger; Friedrich Dorner; Falko G Falkner
Construction of chimeric vaccinia viruses by molecular cloning and packaging.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):9977-81.
1992: Falko G Falkner; Peter L Turecek; R T MacGillivray; W Bodemer; Friedrich Scheiflinger; S Kandels; Artur Mitterer; Otfried Kistner; Noel P Barrett; J Eibl
High level expression of active human prothrombin in a vaccinia virus expression system.
Thrombosis and haemostasis 1992;68(2):119-24.