Graciela Andrei

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McGuigan Christopher; Derudas Marco; Quintiliani Maurizio; Andrei Graciela; Snoeck Robert; Henson Geoffrey; Balzarini Jan
2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.
Vigne Solenne; Duraffour Sophie; Andrei Graciela; Snoeck Robert; Garin Daniel; Crance Jean-Marc
Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir.
McGuigan Christopher; Bidet Olivier; Derudas Marco; Andrei Graciela; Snoeck Robert; Balzarini Jan
Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus.

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2009: McGuigan Christopher; Derudas Marco; Quintiliani Maurizio; Andrei Graciela; Snoeck Robert; Henson Geoffrey; Balzarini Jan
2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.
Bioorganic & medicinal chemistry letters 2009;19(22):6264-7.
2009: Vigne Solenne; Duraffour Sophie; Andrei Graciela; Snoeck Robert; Garin Daniel; Crance Jean-Marc
Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir.
Antimicrobial agents and chemotherapy 2009;53(6):2579-88.
2009: McGuigan Christopher; Bidet Olivier; Derudas Marco; Andrei Graciela; Snoeck Robert; Balzarini Jan
Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus.
Bioorganic & medicinal chemistry 2009;17(8):3025-7.
2009: Naesens Lieve; Vanderlinden Evelien; Roth Erzsébet; Jeko József; Andrei Graciela; Snoeck Robert; Pannecouque Christophe; Illyés Eszter; Batta Gyula; Herczegh Pál; Sztaricskai Ferenc
Anti-influenza virus activity and structure-activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains.
Antiviral research 2009;82(1):89-94.
2008: Gammon Don B; Snoeck Robert; Fiten Pierre; Krecmerová Marcela; Holý Antonín; De Clercq Erik; Opdenakker Ghislain; Evans David H; Andrei Graciela
Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs.
Journal of virology 2008;82(24):12520-34.
2008: Véron Jean-Baptiste; Allouchi Hassan; Enguehard-Gueiffier Cécile; Snoeck Robert; Andrei Graciela; De Clercq Erik; Gueiffier Alain
Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.
Bioorganic & medicinal chemistry 2008;16(21):9536-45.
2008: Naesens Lieve; Andrei Graciela; Votruba Ivan; Krecmerová Marcela; Holý Antonín; Neyts Johan; De Clercq Erik; Snoeck Robert
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine.
Biochemical pharmacology 2008;76(8):997-1005.
2008: McGuigan Christopher; Derudas Marco; Bugert Joachim J; Andrei Graciela; Snoeck Robert; Balzarini Jan
Successful kinase bypass with new acyclovir phosphoramidate prodrugs.
Bioorganic & medicinal chemistry letters 2008;18(15):4364-7.
2008: Dal Pozzo Fabiana; Andrei Graciela; Daelemans Dirk; Winkler Michael; Piette Jacques; De Clercq Erik; Snoeck Robert
Fluorescence-based antiviral assay for the evaluation of compounds against vaccinia virus, varicella zoster virus and human cytomegalovirus.
Journal of virological methods 2008;151(1):66-73.
2008: Andrei Graciela; De Clercq Eric; Snoeck Robert
Novel inhibitors of human CMV.
Current opinion in investigational drugs (London, England : 2000) 2008;9(2):132-45.
2008: Duraffour Sophie; Vigne Solenne; Vermeire Kurt; Garcel Aude; Vanstreels Els; Daelemans Dirk; Yang Guang; Jordan Robert; Hruby Dennis E; Crance Jean-Marc; Garin Daniel; Andrei Graciela; Snoeck Robert
Specific targeting of the F13L protein by ST-246 affects orthopoxvirus production differently.
Antiviral therapy 2008;13(8):977-90.
2008: Vigne Solenne; Germi Raphaële; Duraffour Sophie; Larrat Sylvie; Andrei Graciela; Snoeck Robert; Garin Daniel; Crance Jean-Marc
Specific inhibition of orthopoxvirus replication by a small interfering RNA targeting the D5R gene.
Antiviral therapy 2008;13(3):357-68.
2007: McGuigan Christopher; Pathirana Ranjith N; Migliore Marco; Adak Rina; Luoni Giovanna; Jones Arwyn T; Díez-Torrubia Alberto; Camarasa Maria-Jose; Velázquez Sonsoles; Henson Geoffrey; Verbeken Erik; Sienaert Rebecca; Naesens Lieve; Snoeck Robert; Andrei Graciela; Balzarini Jan
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.
The Journal of antimicrobial chemotherapy 2007;60(6):1316-30.
2007: Duraffour Sophie; Snoeck Robert; Krecmerová Marcela; van Den Oord Joost; De Vos Rita; Holy Antonín; Crance Jean-Marc; Garin Daniel; De Clercq Erik; Andrei Graciela
Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models.
Antimicrobial agents and chemotherapy 2007;51(12):4410-9.
2007: Krecmerová Marcela; Holý Antonín; Pohl Radek; Masojídková Milena; Andrei Graciela; Naesens Lieve; Neyts Johan; Balzarini Jan; De Clercq Erik; Snoeck Robert
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.
Journal of medicinal chemistry 2007;50(23):5765-72.
2007: Dal Pozzo Fabiana; Andrei Graciela; Lebeau Ilya; Beadle James R; Hostetler Karl Y; De Clercq Erik; Snoeck Robert
In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA.
Antiviral research 2007;75(1):52-7.
2007: Andrei G; Fiten P; Goubau P; van Landuyt H; Gordts B; Selleslag D; De Clercq E; Opdenakker G; Snoeck R
Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient.
Transplant infectious disease : an official journal of the Transplantation Society 2007;9(2):126-31.
2007: Lebeau Ilya; Andrei Graciela; Krecmerová Marcela; De Clercq Erik; Holy Antonin; Snoeck Robert
Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains.
Antimicrobial agents and chemotherapy 2007;51(6):2268-73.
2007: Krecmerová Marcela; Holý Antonín; Pískala Alois; Masojídková Milena; Andrei Graciela; Naesens Lieve; Neyts Johan; Balzarini Jan; De Clercq Erik; Snoeck Robert
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
Journal of medicinal chemistry 2007;50(5):1069-77.
2007: Duraffour Sophie; Snoeck Robert; de Vos Rita; van Den Oord Joost J; Crance Jean-Marc; Garin Daniel; Hruby Dennis E; Jordan Robert; De Clercq Erik; Andrei Graciela
Activity of the anti-orthopoxvirus compound ST-246 against vaccinia, cowpox and camelpox viruses in cell monolayers and organotypic raft cultures.
Antiviral therapy 2007;12(8):1205-16.
2007: Maruyama Tokumi; Demizu Yosuke; Kozai Shigetada; Witvrouw Myriam; Pannecouque Christophe; Balzarini Jan; Snoecks Robert; Andrei Graciella; De Clercq Erik
Antiviral activity of 3-(3,5-dimethylbenzyl)uracil derivatives against HIV-1 and HCMV.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1553-8.
2006: Horejsí Katerina; Andrei Graciela; De Clercq Erik; Snoeck Robert; Pohl Radek; Holý Antonín
Tricyclic etheno analogs of PMEG and PMEDAP: synthesis and biological activity.
Bioorganic & medicinal chemistry 2006;14(23):8057-65.
2006: Andrei Graciela; Gammon Don B; Fiten Pierre; De Clercq Erik; Opdenakker Ghislain; Snoeck Robert; Evans David H
Cidofovir resistance in vaccinia virus is linked to diminished virulence in mice.
Journal of virology 2006;80(19):9391-401.
2006: Naesens Lieve; Stephens Chad E; Andrei Graciela; Loregian Arianna; De Bolle Leen; Snoeck Robert; Sowell J Walter; De Clercq Erik
Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses.
Antiviral research 2006;72(1):60-7.
2006: Andrei Graciela
Three-dimensional culture models for human viral diseases and antiviral drug development.
Antiviral research 2006;71(2-3):96-107.
2006: Lebeau Ilya; Andrei Graciela; Dal Pozzo Fabiana; Beadle James R; Hostetler Karl Y; De Clercq Erik; van den Oord Joost; Snoeck Robert
Activities of alkoxyalkyl esters of cidofovir (CDV), cyclic CDV, and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine against orthopoxviruses in cell monolayers and in organotypic cultures.
Antimicrobial agents and chemotherapy 2006;50(7):2525-9.
2006: Maruyama Tokumi; Kozai Shigetada; Demizu Yosuke; Witvrouw Myriam; Pannecouque Christophe; Balzarini Jan; Snoecks Robert; Andrei Graciella; De Clercq Erik
Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives.
Chemical & pharmaceutical bulletin 2006;54(3):325-33.
2005: Dal Pozzo F; Andrei G; Holy A; Van Den Oord J; Scagliarini A; De Clercq E; Snoeck R
Activities of acyclic nucleoside phosphonates against Orf virus in human and ovine cell monolayers and organotypic ovine raft cultures.
Antimicrobial agents and chemotherapy 2005;49(12):4843-52.
2005: Andrei Graciela; van den Oord Joost; Fiten Pierre; Opdenakker Ghislain; De Wolf-Peeters Chris; De Clercq Erik; Snoeck Robert
Organotypic epithelial raft cultures as a model for evaluating compounds against alphaherpesviruses.
Antimicrobial agents and chemotherapy 2005;49(11):4671-80.
2005: Stevens Miguel; Balzarini Jan; Tabarrini Oriana; Andrei Graciela; Snoeck Robert; Cecchetti Violetta; Fravolini Arnaldo; De Clercq Erik; Pannecouque Christophe
Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation.
The Journal of antimicrobial chemotherapy 2005;56(5):847-55.
2005: Scagliarini A; Dal Pozzo F; Gallina L; Guercio A; De Clercq E; Snoeck R; Andrei G
Ovine skin organotypic cultures applied to the ex vivo study of orf virus infection.
Veterinary research communications 2005;29 Suppl 2():245-7.
2005: Luoni Giovanna; McGuigan Christopher; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Bicyclic nucleoside inhibitors of Varicella-Zoster virus: the effect of branching in the p-alkylphenyl side chain.
Bioorganic & medicinal chemistry letters 2005;15(16):3791-6.
2005: Andrei Graciela; Balzarini Jan; Fiten Pierre; De Clercq Erik; Opdenakker Ghislain; Snoeck Robert
Characterization of herpes simplex virus type 1 thymidine kinase mutants selected under a single round of high-dose brivudin.
Journal of virology 2005;79(9):5863-9.
2005: Gerona-Navarro Guillermo; Pérez de Vega M Jesús; García-López M Teresa; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan; González-Muñiz Rosario
From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.
Journal of medicinal chemistry 2005;48(7):2612-21.
2005: Andrei Graciela; Sienaert Rebecca; McGuigan Chris; De Clercq Erik; Balzarini Jan; Snoeck Robert
Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides.
Antimicrobial agents and chemotherapy 2005;49(3):1081-6.
2005: Naesens L; Lenaerts L; Andrei G; Snoeck R; Van Beers D; Holy Antonin; Balzarini Jan; De Clercq Erik
Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.
Antimicrobial agents and chemotherapy 2005;49(3):1010-6.
2005: Kelleher M R; McGuigan C; Bidet O; Carangio A; Weldon H; Andrei G; Snoeck R; De Clercq E; Balzarini J
The journey towards elucidating the anti-HCMV activity of alkylated bicyclic furano pyrimidines.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):643-5.
2005: De Clercq Erik; Andrei G; Balzarini J; Leyssen P; Naesens L; Neyts J; Pannecouque C; Snoeck R; Ying C; Hocková D; Holý A
Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):331-41.
2004: Luoni Giovanna M; McGuigan Christopher; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.
Antiviral chemistry & chemotherapy 2004;15(6):333-41.
2004: Bidet Olivier; McGuigan Christopher; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Non-nucleoside structures retain full anti-HCMV potency of the dideoxy furanopyrimidine family.
Antiviral chemistry & chemotherapy 2004;15(6):329-32.
2004: Balzarini J; Pannecouque C; Naesens L; Andrei G; Snoeck R; De Clercq E; Hocková D; Holý A
6-[2-phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: a new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1321-7.
2004: Snoeck R; de Clercq E; Andrei G
[Using antiviral drugs for Orthopoxvirus infections]
Médecine et maladies infectieuses 2004;34 Suppl 1():S48-50.
2004: Hocková Dana; Holý Antonín; Masojídková Milena; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds.
Bioorganic & medicinal chemistry 2004;12(12):3197-202.
2004: Angell Annette; McGuigan Christopher; Garcia Sevillano Luis; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity.
Bioorganic & medicinal chemistry letters 2004;14(10):2397-9.
2004: Gerona-Navarro Guillermo; Pérez de Vega M Jesús; García-López M Teresa; Andrei Graciela; Snoeck Robert; Balzarini Jan; De Clercq Erik; González-Muñiz Rosario
Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine.
Bioorganic & medicinal chemistry letters 2004;14(9):2253-6.
2004: Andrei G; De Clercq E; Snoeck R
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
Antiviral research 2004;61(3):181-7.
2004: McGuigan Christopher; Pathirana Ranjith N; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.
Journal of medicinal chemistry 2004;47(7):1847-51.
2004: Sienaert R; Andrei G; Snoeck R; De Clercq E; McGuigan C; Balzarini J
Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase.
Biochemical and biophysical research communications 2004;315(4):877-83.
2004: De Bolle Leen; Andrei Graciela; Snoeck Robert; Zhang Ying; Van Lommel Alfons; Otto Michael; Bousseau Anne; Roy Christine; De Clercq Erik; Naesens Lieve
Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423.
Biochemical pharmacology 2004;67(2):325-36.
2004: Maruyama Tokumi; Kozai Shigetada; Demizu Yosuke; Witvrouw Myriam; Pannecouque Christophe; Balzarini Jan; Snoeck Robert; Andrei Graciella; De Clercq Erik
Synthesis and antiviral activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil against HIV-1.
Nucleic acids symposium series (2004) 2004;(48):3-4.
2004: McGuigan Christopher; Carangio Antonella; Snoeck Robert; Andrei Graciela; De Clercq Erik; Balzarini Jan
Synthesis and antiviral evaluation of some 3'-fluoro bicyclic nucleoside analogues.
Nucleosides, nucleotides & nucleic acids 2004;23(1-2):1-5.
2003: McGuigan Christopher; Brancale Andrea; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activity.
Bioorganic & medicinal chemistry letters 2003;13(24):4511-3.
2003: Hocková Dana; Holý Antonín; Masojídková Milena; Andrei Graciela; Snoeck Robert; De Clercq Erik; Balzarini Jan
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity.
Journal of medicinal chemistry 2003;46(23):5064-73.
2003: Maruyama Tokumi; Kozai Shigetada; Yamasaki Tetsuo; Witvrouw Myriam; Pannecouque Christophe; Balzarini Jan; Snoeck Robert; Andrei Graciella; De Clercq Erik
Synthesis and antiviral activity of 1,3-disubstituted uracils against HIV-1 and HCMV.
Antiviral chemistry & chemotherapy 2003;14(5):271-9.
2003: Sienaert R; Naesens L; Brancale A; Carangio A; Andrei G; Snoeck R; Van Kuilenburg A; De Clercq E; McGuigan C; Balzarini J
Metabolic and pharmacological characteristics of the bicyclic nucleoside analogues (BCNAs) as highly selective inhibitors of varicella-zoster virus (VZV).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):995-7.
2003: Carangio A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus: synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro and 2'-deoxy-xylo derivatives.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):935-7.
2003: Luoni G; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus: 5'-chloro and 3'-chloro derivatives.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):931-3.
2003: Bidet O; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis of unusual bicyclic nucleosides bearing an unsaturated side-chain, as potential inhibitors of varicella-zoster virus (VZV).
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):817-9.
2003: McGuigan Christopher; Jukes Alison; Blewett Sally; Barucki Hubert; Erichsen Jonathan T; Andrei Graciella; Snoeck Robert; De Clercq Erik; Balzarini Jan
Halophenyl furanopyrimidines as potent and selective anti-VZV agents.
Antiviral chemistry & chemotherapy 2003;14(3):165-70.
2002: Snoeck R; Holý A; Dewolf-Peeters C; Van Den Oord J; De Clercq E; Andrei G
Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures.
Antimicrobial agents and chemotherapy 2002;46(11):3356-61.
2002: Vermeire Kurt; Zhang Ying; Princen Katrien; Hatse Sigrid; Samala Meinrado F; Dey Kaka; Choi Heung-Jin; Ahn Youngmi; Sodoma Andrej; Snoeck Robert; Andrei Graciela; De Clercq Erik; Bell Thomas W; Schols Dominique
CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor.
Virology 2002;302(2):342-53.
2002: Carangio A; Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus: effect of terminal aryl substitution in the side-chain.
Antiviral chemistry & chemotherapy 2002;13(5):263-71.
2002: Snoeck Robert; Andrei Graciela; Bodaghi Bahram; Lagneaux Laurence; Daelemans Dirk; de Clercq Erik; Neyts Johan; Schols Dominique; Naesens Lieve; Michelson Susan; Bron Dominique; Otto Michael J; Bousseau Anne; Nemecek Conception; Roy Christine
2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections.
Antiviral research 2002;55(3):413-24.
2002: Holý Antonín; Votruba Ivan; Masojídková Milena; Andrei Graciela; Snoeck Robert; Naesens Lieve; De Clercq Erik; Balzarini Jan
6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity.
Journal of medicinal chemistry 2002;45(9):1918-29.
2002: Mavel Sylvie; Renou Jean-Louis; Galtier Christophe; Allouchi Hassan; Snoeck Robert; Andrei Graciella; De Clercq Erik; Balzarini Jan; Gueiffier Alain
Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus.
Bioorganic & medicinal chemistry 2002;10(4):941-6.
2002: McGuigan Christopher; Blewett Sally; Siccardi Dario; Erichsen Jonathan T; Andrei Graciela; Snoek Robert; De Clercq Erik; Balzarini Jan
Alkyloxyphenyl furano pyrimidines as potent and selective anti-VZV agents with enhanced water solubility.
Antiviral chemistry & chemotherapy 2002;13(2):91-9.
2001: Chaouni-Enabdallah A; Galtier C; Allouchi H; Kherbeche A; Chavignon O; Teulade J C; Witvrouw M; Pannecouque C; Snoeck R; Andrei G; Balzarini J; De Clercq E; Fauvelle F; Enguehard C; Gueiffier A
3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents.
Chemical & pharmaceutical bulletin 2001;49(12):1631-5.
2001: Harris S A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Antiviral chemistry & chemotherapy 2001;12(5):293-300.
2001: Brancale A; McGuigan C; Algain B; Savy P; Benhida R; Fourrey J L; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity.
Bioorganic & medicinal chemistry letters 2001;11(18):2507-10.
2001: Andrei G; Fiten P; De Clercq E; Snoeck R; Opdenakker G
Evaluating phenotype and genotype of drug-resistant strains in herpesviruses.
Molecular biotechnology 2001;18(2):155-67.
2001: Carangio A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): Pd-catalysed synthesis of 5-aryl derivatives and their biological evaluation.
Antiviral chemistry & chemotherapy 2001;12(3):187-97.
2001: Stephens C E; Felder T M; Sowell J W; Andrei G; Balzarini J; Snoeck R; De Clercq E
Synthesis and antiviral/antitumor evaluation of 2-amino- and 2-carboxamido-3-arylsulfonylthiophenes and related compounds as a new class of diarylsulfones.
Bioorganic & medicinal chemistry 2001;9(5):1123-32.
2001: Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): effect of terminal unsaturation in the side-chain.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):763-6.
2001: Carangio A; McGuigan C; Cahard D; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis and in vitro evaluation of novel anti-varicella-zoster virus (VZV) nucleosides.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):653-6.
2001: McGuigan C; Barucki H; Carangio A; Blewett S; Srinivasan S; Andrei G; Snoeck R; De Clercq E; Balzarini J
Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):287-96.
2001: De Clercq E; Andrei G; Snoeck R; De Bolle L; Naesens L; Degrève B; Balzarini J; Zhang Y; Schols D; Leyssen P; Ying C; Neyts J
Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):271-85.
2001: Blewett S; McGuigan C; Barucki H; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic furo pyrimidine nucleosides with aryloxyphenyl and halophenyl substituted side chains as potent and selective varicella-zoster virus inhibitors.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):1063-6.
2001: McGuigan C; Brancale A; Barucki H; Srinivasan S; Jones G; Pathirana R; Carangio A; Blewett S; Luoni G; Bidet O; Jukes A; Jarvis C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Furano pyrimidines as novel potent and selective anti-VZV agents.
Antiviral chemistry & chemotherapy 2001;12(2):77-89.
2001: Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of terminal unsaturation in the side chain.
Bioorganic & medicinal chemistry letters 2001;11(3):391-3.
2001: Snoeck R; Andrei G; De Clercq E
Cidofovir in the treatment of HPV-associated lesions.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2001;63(2):93-120, discussion 120-2.
2001: Mavel S; Renou J L; Galtier C; Snoeck R; Andrei G; Balzarini J; De Clercq E; Gueiffier A
Synthesis of imidazo[1,2-a]pyridine derivatives as antiviral agents.
Arzneimittel-Forschung 2001;51(4):304-9.
2000: McGuigan C; Barucki H; Carangio A; Blewett S; Andrei G; Snoeck R; De Clercq E; Balzarini J; Erichsen J T
Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain.
Journal of medicinal chemistry 2000;43(26):4993-7.
2000: Brancale A; Srinivasan S; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Synthesis and anti-varicella-zoster virus activity of some novel bicyclic nucleoside inhibitors: effect of enhanced aqueous solubility.
Antiviral chemistry & chemotherapy 2000;11(6):383-93.
2000: McGuigan C; Pathirana R N; Jones G; Andrei G; Snoeck R; De Clercq E; Balzarini J
Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency.
Antiviral chemistry & chemotherapy 2000;11(5):343-8.
2000: Snoeck R; Andrei G; De Clercq E
Novel agents for the therapy of varicella-zoster virus infections.
Expert opinion on investigational drugs 2000;9(8):1743-51.
2000: Brancale A; McGuigan C; Andrei G; Snoeck R; De Clercq E; Balzarini J
Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain.
Bioorganic & medicinal chemistry letters 2000;10(11):1215-7.
2000: Andrei G; Snoeck R; Neyts J; Sandvold M L; Myhren F; De Clercq E
Antiviral activity of ganciclovir elaidic acid ester against herpesviruses.
Antiviral research 2000;45(3):157-67.
2000: Andrei G; Snoeck R; De Clercq E; Esnouf R; Fiten P; Opdenakker G
Resistance of herpes simplex virus type 1 against different phosphonylmethoxyalkyl derivatives of purines and pyrimidines due to specific mutations in the viral DNA polymerase gene.
The Journal of general virology 2000;81(Pt 3):639-48.
2000: Andrei G; Snoeck R; Schols D; De Clercq E
Induction of apoptosis by cidofovir in human papillomavirus (HPV)-positive cells.
Oncology research 2000;12(9-10):397-408.
1999: McGuigan C; Yarnold C J; Jones G; Velázquez S; Barucki H; Brancale A; Andrei G; Snoeck R; De Clercq E; Balzarini J
Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base.
Journal of medicinal chemistry 1999;42(22):4479-84.
1999: Holý A; Günter J; Dvoráková H; Masojídková M; Andrei G; Snoeck R; Balzarini J; De Clercq E
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.
Journal of medicinal chemistry 1999;42(12):2064-86.
1999: De Clercq E; Andrei G; Balzarini J; Hatse S; Liekens S; Naesens L; Neyts J; Snoeck R
Antitumor potential of acyclic nucleoside phosphonates.
Nucleosides & nucleotides 1999;18(4-5):759-71.
1999: Martinez A; Esteban A I; Castro A; Gil C; Conde S; Andrei G; Snoeck R; Balzarini J; De Clercq E
Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides.
Journal of medicinal chemistry 1999;42(7):1145-50.
1999: Snoeck R; Andrei G; De Clercq E
Current pharmacological approaches to the therapy of varicella zoster virus infections: a guide to treatment.
Drugs 1999;57(2):187-206.
1998: Gueiffier A; Mavel S; Lhassani M; Elhakmaoui A; Snoeck R; Andrei G; Chavignon O; Teulade J C; Witvrouw M; Balzarini J; De Clercq E; Chapat J P
Synthesis of imidazo[1,2-a]pyridines as antiviral agents.
Journal of medicinal chemistry 1998;41(25):5108-12.
1998: Neyts J; Andrei G; De Clercq E
The antiherpesvirus activity of H2G [(R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine] is markedly enhanced by the novel immunosuppressive agent mycophenolate mofetil.
Antimicrobial agents and chemotherapy 1998;42(12):3285-9.
1998: Witvrouw M; Daelemans D; Pannecouque C; Neyts J; Andrei G; Snoeck R; Vandamme A M; Balzarini J; Desmyter J; Baba M; De Clercq E
Broad-spectrum antiviral activity and mechanism of antiviral action of the fluoroquinolone derivative K-12.
Antiviral chemistry & chemotherapy 1998;9(5):403-11.
1998: Liekens S; Andrei G; Vandeputte M; De Clercq E; Neyts J
Potent inhibition of hemangioma formation in rats by the acyclic nucleoside phosphonate analogue cidofovir.
Cancer research 1998;58(12):2562-7.
1998: Balzarini J; Degrève B; Andrei G; Neyts J; Sandvold M; Myhren F; de Clercq E
Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells.
Gene therapy 1998;5(3):419-26.
1998: Neyts J; Andrei G; De Clercq E
The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir, ganciclovir, and penciclovir in vitro and in vivo.
Antimicrobial agents and chemotherapy 1998;42(2):216-22.
1998: Neyts J; Balzarini J; Andrei G; Chaoyong Z; Snoeck R; Zimmermann A; Mertens T; Karlsson A; De Clercq E
Intracellular metabolism of the N7-substituted acyclic nucleoside analog 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a potent inhibitor of herpesvirus replication.
Molecular pharmacology 1998;53(1):157-65.
1998: Andrei G; Snoeck R; Piette J; Delvenne P; De Clercq E
Inhibiting effects of cidofovir (HPMPC) on the growth of the human cervical carcinoma (SiHa) xenografts in athymic nude mice.
Oncology research 1998;10(10):533-9.
1998: Andrei G; Snoeck R; Piette J; Delvenne P; De Clercq E
Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines.
Oncology research 1998;10(10):523-31.
1997: Degrève B; Andrei G; Izquierdo M; Piette J; Morin K; Knaus E E; Wiebe L I; Basrah I; Walker R T; De Clercq E; Balzarini J
Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer.
Gene therapy 1997;4(10):1107-14.
1997: Andrei G; Snoeck R; Vandeputte M; De Clercq E
Activities of various compounds against murine and primate polyomaviruses.
Antimicrobial agents and chemotherapy 1997;41(3):587-93.
1996: Snoeck R; Andrei G; De Clercq E
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1996;15(7):574-9.
1996: Leydet A; El Hachemi H; Boyer B; Lamaty G; Roque J P; Schols D; Snoeck R; Andrei G; Ikeda S; Neyts J; Reymen D; Este J; Witvrouw M; De Clercq E
Polyanion inhibitors of human immunodeficiency virus and other viruses. Part 2. Polymerized anionic surfactants derived from amino acids and dipeptides.
Journal of medicinal chemistry 1996;39(8):1626-34.
1995: Balzarini J; Andrei G; Kumar R; Knaus E E; Wiebe L I; De Clercq E
The cytostatic activity of 5-(1-azidovinyl)-2'-deoxyuridine (AzVDU) against herpes simplex virus thymidine kinase gene-transfected FM3A cells is due to inhibition of thymidylate synthase and enhanced by UV light (lambda = 254 nm) exposure.
FEBS letters 1995;373(1):41-4.
1995: Neyts J; Reymen D; Letourneur D; Jozefonvicz J; Schols D; Este J; Andrei G; McKenna P; Witvrouw M; Ikeda S
Differential antiviral activity of derivatized dextrans.
Biochemical pharmacology 1995;50(6):743-51.
1995: Andrei G; Snoeck R; De Clercq E
Susceptibilities of several drug-resistant herpes simplex virus type 1 strains to alternative antiviral compounds.
Antimicrobial agents and chemotherapy 1995;39(7):1632-5.
1995: Leydet A; Barthelemy P; Boyer B; Lamaty G; Roque J P; Bousseau A; Evers M; Hénin Y; Snoeck R; Andrei G
Polyanion inhibitors of human immunodeficiency virus and other viruses. 1. Polymerized anionic surfactants.
Journal of medicinal chemistry 1995;38(13):2433-40.
1995: Andrei G; Snoeck R; Reymen D; Liesnard C; Goubau P; Desmyter J; De Clercq E
Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1995;14(4):318-29.
1995: Verheggen I; Van Aerschot A; Van Meervelt L; Rozenski J; Wiebe L; Snoeck R; Andrei G; Balzarini J; Claes P; De Clercq E
Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.
Journal of medicinal chemistry 1995;38(5):826-35.
1995: Neyts J; Jähne G; Andrei G; Snoeck R; Winkler I; De Clercq E
In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine.
Antimicrobial agents and chemotherapy 1995;39(1):56-60.
1994: Neyts J; Andrei G; Snoeck R; Jähne G; Winkler I; Helsberg M; Balzarini J; De Clercq E
The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication.
Antimicrobial agents and chemotherapy 1994;38(12):2710-6.
1994: Damonte E; Neyts J; Pujol C A; Snoeck R; Andrei G; Ikeda S; Witvrouw M; Reymen D; Haines H; Matulewicz M C
Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata.
Biochemical pharmacology 1994;47(12):2187-92.
1994: Snoeck R; Gérard M; Sadzot-Delvaux C; Andrei G; Balzarini J; Reymen D; Ahadi N; De Bruyn J M; Piette J; Rentier B
Meningoradiculoneuritis due to acyclovir-resistant varicella zoster virus in an acquired immune deficiency syndrome patient.
Journal of medical virology 1994;42(4):338-47.
1994: Snoeck R; Andrei G; Gérard M; Silverman A; Hedderman A; Balzarini J; Sadzot-Delvaux C; Tricot G; Clumeck N; De Clercq E
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1994;18(4):570-8.
1993: Snoeck R; Gérard M; Sadzot-Delvaux C; Andrei G; Balzarini J; Reymen D; Piette J; Rentier B; Clumeck N; De Clercq E
Meningoradiculoneuritis due to acyclovir-resistant varicella-zoster virus in a patient with AIDS.
The Journal of infectious diseases 1993;168(5):1330-1.
1993: Snoeck R; Andrei G; De Clercq E; Gerard M; Clumeck N; Tricot G; Sadzot-Delvaux C
A new topical treatment for resistant herpes simplex infections.
The New England journal of medicine 1993;329(13):968-9.
1993: Andrei G; De Clercq E
Molecular approaches for the treatment of hemorrhagic fever virus infections.
Antiviral research 1993;22(1):45-75.
1993: Snoeck R; Andrei G; Neyts J; Schols D; Cools M; Balzarini J; De Clercq E
Inhibitory activity of S-adenosylhomocysteine hydrolase inhibitors against human cytomegalovirus replication.
Antiviral research 1993;21(3):197-216.
1992: Snoeck R; Andrei G; Schols D; Balzarini J; De Clercq E
Activity of different antiviral drug combinations against human cytomegalovirus replication in vitro.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1992;11(12):1144-55.
1992: Snoeck R; Schols D; Sadzot-Delvaux C; Cloes J M; Andrei G; De Clercq E; Piette J; Rentier B
Flow cytometric method for the detection of gpI antigens of varicella zoster virus and evaluation of anti-VZV agents.
Journal of virological methods 1992;38(2):243-54.
1992: Andrei G; Snoeck R; Goubau P; Desmyter J; De Clercq E
Comparative activity of various compounds against clinical strains of herpes simplex virus.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1992;11(2):143-51.
1991: Andrei G; Snoeck R; Schols D; Goubau P; Desmyter J; De Clercq E
Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1991;10(12):1026-33.
1991: Snoeck R; Schols D; Andrei G; Neyts J; De Clercq E
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.
Antiviral research 1991;16(1):1-9.
1991: De Clercq E; Cools M; Balzarini J; Snoeck R; Andrei G; Hosoya M; Shigeta S; Ueda T; Minakawa N; Matsuda A
Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds.
Antimicrobial agents and chemotherapy 1991;35(4):679-84.
1990: Andrei G; De Clercq E
Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro.
Antiviral research 1990;14(4-5):287-99.
1990: Andrei G M; Coulombie F C; Courreges M C; de Torres R A; Coto C E
Meliacine, an antiviral compound from Melia azedarach L., inhibits interferon production.
Journal of interferon research 1990;10(5):469-75.
1988: Andrei G M; Damonte E B; de Torres R A; Coto C E
Induction of a refractory state to viral infection in mammalian cells by a plant inhibitor isolated from leaves of Melia azedarach L.
Antiviral research 1988;9(4):221-31.
1986: Andrei G M; Lampuri J S; Coto C E; de Torres R A
An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice.
Experientia 1986;42(7):843-5.
1985: Andrei G M; Coto C E; de Torres R A
[Assays of cytotoxicity and antiviral activity of crude and semipurified extracts of green leaves of Melia azedarach L.]
Revista Argentina de microbiología 1985;17(4):187-94.

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