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Joachim Fandrey

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TOP 3
Joachim Fandrey
Highlight: sensing hypoxia in the cell and the organism.
Regina Wobben; Joachim Fandrey; Kathrin Gibbert; Yvonne Hüsecken; Claudia Lodewick; Sandra Winning
Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cells.
Kristin Franke; Max Gassmann; Kathrin Geiger; David R Greaves; Vasuprada Iyengar; Steffen Jahn; Joanna Kalucka; Soulafa Mamlouk; Michael Muders; Antje Muschter; Teresa Otto; David M Poitz; Tatsiana Ripich; Rashim Pal Singh; Alex M Sykes; Alexander Weidemann; Kathrin Wieczorek; Gustavo Baretton; Sybille Bergmann; Stefan Bornstein; Georg Breier; Triantafyllos Chavakis; Joachim Fandrey; Guo-Hua Fong; Ben Wielockx
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.

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2013: Joachim Fandrey
Highlight: sensing hypoxia in the cell and the organism.
Biological chemistry 2013;394(4):433-4.
2013: Regina Wobben; Joachim Fandrey; Kathrin Gibbert; Yvonne Hüsecken; Claudia Lodewick; Sandra Winning
Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cells.
Biological chemistry 2013;394(4):495-505.
2013: Kristin Franke; Max Gassmann; Kathrin Geiger; David R Greaves; Vasuprada Iyengar; Steffen Jahn; Joanna Kalucka; Soulafa Mamlouk; Michael Muders; Antje Muschter; Teresa Otto; David M Poitz; Tatsiana Ripich; Rashim Pal Singh; Alex M Sykes; Alexander Weidemann; Kathrin Wieczorek; Gustavo Baretton; Sybille Bergmann; Stefan Bornstein; Georg Breier; Triantafyllos Chavakis; Joachim Fandrey; Guo-Hua Fong; Ben Wielockx
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Blood 2013;121(8):1436-45.
2013: M Wiesweg; Frank Petrat; Utta Berchner-Pfannschmidt; Herbert de Groot; Joachim Fandrey; Michael Kirsch
Rocket fuel for the quantification of S-nitrosothiols. Highly specific reduction of S-nitrosothiols to thiols by methylhydrazine.
Free radical research 2013;47(2):104-15.
2013: Michael Adamzik; Arne Becker; Joachim Fandrey; Stilla Frede; Ulrich H Frey; Maximiliane Kreuzer; Jürgen Peters; Simon Schäfer; Winfried Siffert; Jörg Steinmann; Sandra Winning; Kai Zacharowski; Matthias Hartmann
The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.
Anesthesiology 2013;118(1):123-33.
2012: Friederike Katharina Pientka; Susann G Schindler; Anika Thiel; Utta Berchner-Pfannschmidt; Britta Brix; Joachim Fandrey; Jun Hu; Olaf Jöhren; Reinhard Depping
Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
Journal of cell science 2012;125(Pt 21):5168-76.
2012: Joachim Fandrey
Why not the liver instead of the kidney?
Blood 2012;120(9):1760-1.
2012: Anna-Katharina Meinecke; Nadine Nagy; Véronique Orian-Rousseau; Helene Rundqvist; Katrin Schrödter; Dirk Theegarten; Annika Zimmermann; Kari Alitalo; Olaf Anhenn; Joachim Fandrey; Jens W Fischer; Iris Helfrich; Randall S Johnson; Santina Kirmse; Ralph Klose; Gabriela D'Amico Lago; Christian Stockmann
Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis.
Blood 2012;119(24):5931-42.
2012: Helene Niecknig; Buena Delos Reyes; Suzan Tug; Joachim Fandrey; Michael Kirsch; Utta Berchner-Pfannschmidt
Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia.
Free radical research 2012;46(6):705-17.
2012: Kristin Wollenick; Roland H Wenger; Utta Berchner-Pfannschmidt; Joachim Fandrey; Jun Hu; Glen Kristiansen; Hubert Rehrauer; Peter Schraml; Daniel Stiehl
Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.
Nucleic acids research 2012;40(5):1928-43.
2011: Christoph Wotzlaw; Dmitri Papkovsky; Helmut Acker; Utta Berchner-Pfannschmidt; André Bernardini; Joachim Fandrey
Multifocal animated imaging of changes in cellular oxygen and calcium concentrations and membrane potential within the intact adult mouse carotid body ex vivo.
American journal of physiology. Cell physiology 2011;301(2):C266-71.
2011: Nathalie Dehne; Uta Kerkweg; Stefanie B Flohé; Bernhard Brüne; Joachim Fandrey
Activation of hypoxia-inducible factor 1 in skeletal muscle cells after exposure to damaged muscle cell debris.
Shock (Augusta, Ga.) 2011;35(6):632-8.
2011: Stilla Frede; Patricia Freitag; Luise Geuting; Rebecca Konietzny; Joachim Fandrey
Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC.
Blood 2011;117(18):4905-14.
2011: Ulf Brockmeier; Corinna Platzek; Kirsten Schneider; Pauline Patak; André Bernardini; Joachim Fandrey; Eric Metzen
The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9.
PloS one 2011;6(4):e19151.
2010: Sandra Winning; Frank Splettstoesser; Joachim Fandrey; Stilla Frede
Acute hypoxia induces HIF-independent monocyte adhesion to endothelial cells through increased intercellular adhesion molecule-1 expression: the role of hypoxic inhibition of prolyl hydroxylase activity for the induction of NF-kappa B.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(3):1786-93.
2010: N Scheerer; Nicole Dünker; S Imagawa; M Yamamoto; Norio Suzuki; Joachim Fandrey
The anemia of the newborn induces erythropoietin expression in the developing mouse retina.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;299(1):R111-8.
2010: Utta Berchner-Pfannschmidt; Suzan Tug; Jun Hu; Buena Delos Reyes; Joachim Fandrey; Michael Kirsch
Role of N-acetyl-N-nitroso-tryptophan as nitric oxide donor in the modulation of HIF-1-dependent signaling.
Biological chemistry 2010;391(5):533-40.
2010: Utta Berchner-Pfannschmidt; Suzan Tug; Michael Kirsch; Joachim Fandrey
Oxygen-sensing under the influence of nitric oxide.
Cellular signalling 2010;22(3):349-56.
2010: Tamas Benko; Stilla Frede; Yanli Gu; Jan Best; Hideo Andreas Baba; Jörg Friedrich Schlaak; Herbert de Groot; Joachim Fandrey; Ursula Rauen
Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2010;23(1):12-20.
2010: Jorge Ruas; Utta Berchner-Pfannschmidt; Sohail Malik; Katarina Gradin; Joachim Fandrey; Robert G Roeder; Teresa Pereira; Lorenz Poellinger
Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.
The Journal of biological chemistry 2010;285(4):2601-9.
2010: Christoph Wotzlaw; Silke Gneuss; Rebecca Konietzny; Joachim Fandrey
Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software.
PMC biophysics 2010;3(1):5.
2009: Klaus J Schmitz; Carmen Ina Müller; Henning Reis; Hakan Alakus; Günther Winde; Hideo Andreas Baba; Jeremias Wohlschlaeger; Bharat Jasani; Joachim Fandrey; Kurt W Schmid
Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma.
International journal of colorectal disease 2009;24(11):1287-96.
2009: Rebecca Konietzny; Anna König; Christoph Wotzlaw; André Bernadini; Utta Berchner-Pfannschmidt; Joachim Fandrey
Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT.
Annals of the New York Academy of Sciences 2009;1177():74-81.
2009: Sandra Barth; Frank Edlich; Utta Berchner-Pfannschmidt; Silke Gneuss; Günther Jahreis; Philippe A Hasgall; Joachim Fandrey; Roland H Wenger; Gieri Camenisch
Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.
The Journal of biological chemistry 2009;284(34):23046-58.
2009: Suzan Tug; Buena Delos Reyes; Joachim Fandrey; Utta Berchner-Pfannschmidt
Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors.
Biochemical and biophysical research communications 2009;384(4):519-23.
2009: Stilla Frede; Christian Stockmann; Sandra Winning; Patricia Freitag; Joachim Fandrey
Hypoxia-inducible factor (HIF) 1alpha accumulation and HIF target gene expression are impaired after induction of endotoxin tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6470-6.
2009: Joachim Fandrey; Mario Dicato
Examining the involvement of erythropoiesis-stimulating agents in tumor proliferation (erythropoietin receptors, receptor binding, signal transduction), angiogenesis, and venous thromboembolic events.
The oncologist 2009;14 Suppl 1():34-42.
2009: Joachim Fandrey; Max Gassmann
Oxygen sensing and the activation of the hypoxia inducible factor 1 (HIF-1)--invited article.
Advances in experimental medicine and biology 2009;648():197-206.
2009: Thorsten Bramey; Patricia Freitag; Joachim Fandrey; Ursula Rauen; Katja Pamp; Jochen Erhard; Stilla Frede; Herbert de Groot; Frank Petrat
No evidence for protective erythropoietin alpha signalling in rat hepatocytes.
BMC gastroenterology 2009;9():26.
2008: Christoph Wotzlaw; Utta Berchner-Pfannschmidt; Joachim Fandrey; Helmut Acker
Two-photon imaging of cellular activities in oxygen sensing tissues.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2008;14(6):519-25.
2008: Utta Berchner-Pfannschmidt; Suzan Tug; Buena Trinidad; Felix Oehme; Hatice Yamac; Christoph Wotzlaw; Ingo Flamme; Joachim Fandrey
Nuclear oxygen sensing: induction of endogenous prolyl-hydroxylase 2 activity by hypoxia and nitric oxide.
The Journal of biological chemistry 2008;283(46):31745-53.
2008: Utta Berchner-Pfannschmidt; Suzan Tug; Buena Trinidad; Maria Becker; Felix Oehme; Ingo Flamme; Joachim Fandrey; Michael Kirsch
The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments.
Journal of pineal research 2008;45(4):489-96.
2008: Joachim Fandrey
Erythropoiesis--once more HIF!
Blood 2008;112(4):931-2.
2008: Utta Berchner-Pfannschmidt; Stilla Frede; Christoph Wotzlaw; Joachim Fandrey
Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing.
The European respiratory journal 2008;32(1):210-7.
2008: Teresa Otto; Joachim Fandrey
Thyroid hormone induces hypoxia-inducible factor 1alpha gene expression through thyroid hormone receptor beta/retinoid x receptor alpha-dependent activation of hepatic leukemia factor.
Endocrinology 2008;149(5):2241-50.
2008: Joachim Fandrey
Erythropoietin receptors on tumor cells: what do they mean?
The oncologist 2008;13 Suppl 3():16-20.
2007: S Ehrentraut; Stilla Frede; Heidi Stapel; T Mengden; Christian Grohé; Joachim Fandrey; Rainer Meyer; Georg Baumgarten
Antagonism of lipopolysaccharide-induced blood pressure attenuation and vascular contractility.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(10):2170-6.
2007: Nathalie Dehne; Uta Kerkweg; Teresa Otto; Joachim Fandrey
The HIF-1 response to simulated ischemia in mouse skeletal muscle cells neither enhances glycolysis nor prevents myotube cell death.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(4):R1693-701.
2007: Anna Severino; Mara Campioni; Stefania Straino; Fadi Salloum; Nina Schmidt; Ulrike Herbrand; Stilla Frede; Gabriele Toietta; Giuliana Di Rocco; Rossana Bussani; Furio Silvestri; Maddalena Piro; Giovanna Liuzzo; Luigi M Biasucci; Pasquale Mellone; Florinda Feroce; Maurizio Capogrossi; Feliciano Baldi; Joachim Fandrey; Michael Ehrmann; Filippo Crea; Antonio Abbate; Alfonso Baldi
Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy.
Journal of the American College of Cardiology 2007;50(11):1029-37.
2007: M Hörbelt; Christoph Wotzlaw; Timothy A Sutton; Bruce A Molitoris; Thomas Philipp; Andreas Kribben; Joachim Fandrey; Frank Pietruck
Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy.
Kidney international 2007;72(4):422-9.
2007: Christoph Wotzlaw; Teresa Otto; Utta Berchner-Pfannschmidt; Eric Metzen; Helmut Acker; Joachim Fandrey
Optical analysis of the HIF-1 complex in living cells by FRET and FRAP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(3):700-7.
2007: Utta Berchner-Pfannschmidt; Hatice Yamac; Buena Trinidad; Joachim Fandrey
Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.
The Journal of biological chemistry 2007;282(3):1788-96.
2007: Stilla Frede; Utta Berchner-Pfannschmidt; Joachim Fandrey
Regulation of hypoxia-inducible factors during inflammation.
Methods in enzymology 2007;435():405-19.
2006: Christian Stockmann; Joachim Fandrey
Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression.
Clinical and experimental pharmacology & physiology 2006;33(10):968-79.
2006: Joachim Fandrey
A cordial affair - erythropoietin and cardioprotection.
Cardiovascular research 2006;72(1):1-2.
2006: Utta Berchner-Pfannschmidt; Helmut Acker; Joachim Fandrey
Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;101(3):1000; author reply 1004-5.
2006: Joachim Fandrey; Thomas A Gorr; Max Gassmann
Regulating cellular oxygen sensing by hydroxylation.
Cardiovascular research 2006;71(4):642-51.
2006: Till Acker; Joachim Fandrey; Helmut Acker
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases.
Cardiovascular research 2006;71(2):195-207.
2006: Stilla Frede; Christian Stockmann; Patricia Freitag; Joachim Fandrey
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB.
The Biochemical journal 2006;396(3):517-27.
2005: Helen Burmester; Eva-Maria Wolber; Patricia Freitag; Joachim Fandrey; Wolfgang Jelkmann
Thrombopoietin production in wild-type and interleukin-6 knockout mice with acute inflammation.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2005;25(7):407-13.
2005: Stilla Frede; Patricia Freitag; Teresa Otto; Christina Heilmaier; Joachim Fandrey
The proinflammatory cytokine interleukin 1beta and hypoxia cooperatively induce the expression of adrenomedullin in ovarian carcinoma cells through hypoxia inducible factor 1 activation.
Cancer research 2005;65(11):4690-7.
2005: Peter Vaupel; Jürgen Dunst; Andreas Engert; Joachim Fandrey; Petra Feyer; Mathias Freund; Wolfgang Jelkmann
Effects of recombinant human erythropoietin (rHuEPO) on tumor control in patients with cancer-induced anemia.
Onkologie 2005;28(4):216-21.
2005: Gustavo Pacheco-López; Maj-Britt Niemi; Wei Kou; Margarete Härting; Joachim Fandrey; Manfred Schedlowski
Neural substrates for behaviorally conditioned immunosuppression in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(9):2330-7.
2005: Joachim Fandrey
High-altitude polycythemia.
Haematologica 2005;90(1):1.
2004: Utta Berchner-Pfannschmidt; Frank Petrat; Kathrin Doege; Buena Trinidad; Patricia Freitag; Eric Metzen; Herbert de Groot; Joachim Fandrey
Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha.
The Journal of biological chemistry 2004;279(43):44976-86.
2004: Jochen Rössler; Ineke Stolze; Stilla Frede; Patricia Freitag; Lothar Schweigerer; Werner Havers; Joachim Fandrey
Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site.
Journal of cellular biochemistry 2004;93(1):153-61.
2004: Yaluan Ma; Patricia Freitag; Jie Zhou; Bernhard Brüne; Stilla Frede; Joachim Fandrey
Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;287(3):R600-7.
2004: Hao Zhu; Kevin Larade; Timothy A Jackson; Jianxin Xie; Annie Ladoux; Helmut Acker; Utta Berchner-Pfannschmidt; Joachim Fandrey; Andrew R Cross; Gudrun S Lukat-Rodgers; Kenton R Rodgers; H Franklin Bunn
NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum.
The Journal of biological chemistry 2004;279(29):30316-25.
2004: Joachim Fandrey
Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(6):R977-88.
2004: Jo Hasegawa; Klaus F Wagner; Dörte Karp; Dechun Li; Junpei Shibata; Matthias Heringlake; Ludger Bahlmann; Reinhard Depping; Joachim Fandrey; Peter Schmucker; Stefan Uhlig
Altered pulmonary vascular reactivity in mice with excessive erythrocytosis.
American journal of respiratory and critical care medicine 2004;169(7):829-35.
2004: Utta Berchner-Pfannschmidt; Christoph Wotzlaw; Evelyne Merten; Helmut Acker; Joachim Fandrey
Visualization of the three-dimensional organization of hypoxia-inducible factor-1 alpha and interacting cofactors in subnuclear structures.
Biological chemistry 2004;385(3-4):231-7.
2004: Joachim Fandrey
Oxygen and the cell.
Biological chemistry 2004;385(3-4):203-4.
2004: Christof Dame; Martha C Sola; Kim-Chew Lim; Kelly M Leach; Joachim Fandrey; Yaluan Ma; Gisela Knöpfle; James Douglas Engel; Jörg Bungert
Hepatic erythropoietin gene regulation by GATA-4.
The Journal of biological chemistry 2004;279(4):2955-61.
2003: Eric Metzen; Jie Zhou; Wolfgang Jelkmann; Joachim Fandrey; Bernhard Brüne
Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases.
Molecular biology of the cell 2003;14(8):3470-81.
2003: Christof Dame; Eva-Maria Wolber; Patricia Freitag; Dietmar Hofmann; Peter Bartmann; Joachim Fandrey
Thrombopoietin gene expression in the developing human central nervous system.
Brain research. Developmental brain research 2003;143(2):217-23.
2003: Junpei Shibata; Jo Hasegawa; Hans-Joachim G Siemens; Eva-Maria Wolber; Leif Dibbelt; Dechun Li; Dörthe M Katschinski; Joachim Fandrey; Wolfgang Jelkmann; Max Gassmann; Roland H Wenger; Klaus F Wagner
Hemostasis and coagulation at a hematocrit level of 0.85: functional consequences of erythrocytosis.
Blood 2003;101(11):4416-22.
2003: Agnes Görlach; Utta Berchner-Pfannschmidt; Christoph Wotzlaw; Robbert Cool; Joachim Fandrey; Helmut Acker; Kurt Jungermann; Thomas Kietzmann
Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1.
Thrombosis and haemostasis 2003;89(5):926-35.
2003: Eric Metzen; Utta Berchner-Pfannschmidt; Petra Stengel; Jan H Marxsen; Ineke Stolze; Matthias Klinger; Wei Qi Huang; Christoph Wotzlaw; Thomas Hellwig-Bürgel; Wolfgang Jelkmann; Helmut Acker; Joachim Fandrey
Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
Journal of cell science 2003;116(Pt 7):1319-26.
2003: Jie Zhou; Joachim Fandrey; Jens Schümann; Gisa Tiegs; Bernhard Brüne
NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells.
American journal of physiology. Cell physiology 2003;284(2):C439-46.
2002: Christof Dame; Martha C Sola; Joachim Fandrey; Lisa M Rimsza; Patricia Freitag; Gisela Knöpfle; Robert D Christensen; Jörg Bungert
Developmental changes in the expression of transcription factors GATA-1, -2 and -3 during the onset of human medullary haematopoiesis.
British journal of haematology 2002;119(2):510-5.
2002: Ineke Stolze; Utta Berchner-Pfannschmidt; Patricia Freitag; Christoph Wotzlaw; Jochen Rössler; Stilla Frede; Helmut Acker; Joachim Fandrey
Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells.
Blood 2002;100(7):2623-8.
2001: Eva-Maria Wolber; Joachim Fandrey; U Frackowski; Wolfgang Jelkmann
Hepatic thrombopoietin mRNA is increased in acute inflammation.
Thrombosis and haemostasis 2001;86(6):1421-4.
2001: Klaus F Wagner; Dörthe M Katschinski; Jo Hasegawa; D Schumacher; Birgit Meller; Ulrich Gembruch; Uda Schramm; Wolfgang Jelkmann; Max Gassmann; Joachim Fandrey
Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin.
Blood 2001;97(2):536-42.
2001: Eric Metzen; G Giesen; Joachim Fandrey; Wolfgang Jelkmann
Cytosolic Ca(2+) levels and DNA synthesis of human umbilical vein endothelial cell cultures are unresponsive to thrombopoietin treatment.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2001;11(4):197-202.
2000: Christof Dame; Peter Bartmann; Eva-Maria Wolber; Hubert Fahnenstich; Dietmar Hofmann; Joachim Fandrey
Erythropoietin gene expression in different areas of the developing human central nervous system.
Brain research. Developmental brain research 2000;125(1-2):69-74.
2000: B Bölling; Joachim Fandrey; P J Frosch; Helmut Acker
VEGF production, cell proliferation and apoptosis of human IGR 1 melanoma cells under nIFN-alpha/beta and rIFN-gamma treatment.
Experimental dermatology 2000;9(5):327-35.
2000: Just Genius; Joachim Fandrey
Nitric oxide affects the production of reactive oxygen species in hepatoma cells: implications for the process of oxygen sensing.
Free radical biology & medicine 2000;29(6):515-21.
2000: Dörthe M Katschinski; K Boos; Susann G Schindler; Joachim Fandrey
Pivotal role of reactive oxygen species as intracellular mediators of hyperthermia-induced apoptosis.
The Journal of biological chemistry 2000;275(28):21094-8.
2000: B El Awad; Burkhard Kreft; Eva-Maria Wolber; Thomas Hellwig-Bürgel; Eric Metzen; Joachim Fandrey; Wolfgang Jelkmann
Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells.
Kidney international 2000;58(1):43-50.
2000: Joachim Fandrey; Just Genius
Reactive oxygen species as regulators of oxygen dependent gene expression.
Advances in experimental medicine and biology 2000;475():153-9.
1999: Thomas Hellwig-Bürgel; K Rutkowski; Eric Metzen; Joachim Fandrey; Wolfgang Jelkmann
Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1.
Blood 1999;94(5):1561-7.
1999: Dörthe M Katschinski; H Ian Robins; M Schad; Stilla Frede; Joachim Fandrey
Role of tumor necrosis factor alpha in hyperthermia-induced apoptosis of human leukemia cells.
Cancer research 1999;59(14):3404-10.
1999: Eva-Maria Wolber; Christof Dame; Hubert Fahnenstich; Dietmar Hofmann; Peter Bartmann; Wolfgang Jelkmann; Joachim Fandrey
Expression of the thrombopoietin gene in human fetal and neonatal tissues.
Blood 1999;94(1):97-105.
1999: Eric Metzen; Joachim Fandrey; Wolfgang Jelkmann
Evidence against a major role for Ca2+ in hypoxia-induced gene expression in human hepatoma cells (Hep3B).
The Journal of physiology 1999;517 ( Pt 3)():651-7.
1999: Horst Pagel; Joachim Fandrey; W Schobersberger; D Fuchs; Wolfgang Jelkmann
Effects of neopterin and 7,8-dihydroneopterin on hypoxia-induced renal erythropoietin production.
European journal of haematology 1999;62(5):341-5.
1999: S Bichet; Roland H Wenger; Gieri Camenisch; A Rolfs; W Ehleben; T Porwol; Helmut Acker; Joachim Fandrey; Christian Bauer; Max Gassmann
Oxygen tension modulates beta-globin switching in embryoid bodies.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(2):285-95.
1999: I Neumcke; B Schneider; Joachim Fandrey; Horst Pagel
Effects of pro- and antioxidative compounds on renal production of erythropoietin.
Endocrinology 1999;140(2):641-5.
1998: W Ehleben; T Porwol; Joachim Fandrey; Helmut Acker
The influence of phenobarbital on cytochromes and reactive oxygen species in erythropoietin producing HepG2 cells.
FEBS letters 1998;440(3):343-7.
1998: M Wördemann; Joachim Fandrey; Wolfgang Jelkmann
Tumor necrosis factor-alpha production by human hepatoma cell lines is resistant to drugs that are inhibitory to macrophages.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1998;18(12):1069-75.
1998: orhan Canbolat; Joachim Fandrey; Wolfgang Jelkmann
Effects of modulators of the production and degradation of hydrogen peroxide on erythropoietin synthesis.
Respiration physiology 1998;114(2):175-83.
1998: Christof Dame; Hubert Fahnenstich; Patricia Freitag; Dietmar Hofmann; T Abdul-Nour; Peter Bartmann; Joachim Fandrey
Erythropoietin mRNA expression in human fetal and neonatal tissue.
Blood 1998;92(9):3218-25.
1998: T Porwol; W Ehleben; Karl Zierold; Joachim Fandrey; Helmut Acker
The influence of nickel and cobalt on putative members of the oxygen-sensing pathway of erythropoietin-producing HepG2 cells.
European journal of biochemistry / FEBS 1998;256(1):16-23.
1997: Stilla Frede; Joachim Fandrey; Horst Pagel; T Hellwig; Wolfgang Jelkmann
Erythropoietin gene expression is suppressed after lipopolysaccharide or interleukin-1 beta injections in rats.
The American journal of physiology 1997;273(3 Pt 2):R1067-71.
1997: M Wolff; Joachim Fandrey; A Hirner; Wolfgang Jelkmann
Perioperative use of recombinant human erythropoietin in patients refusing blood transfusions. Pathophysiological considerations based on 5 cases.
European journal of haematology 1997;58(3):154-9.
1997: V Vogel; Herbert kramer; Angela Bäcker; Harald Meyer-Lehnert; Wolfgang Jelkmann; Joachim Fandrey
Effects of erythropoietin on endothelin-1 synthesis and the cellular calcium messenger system in vascular endothelial cells.
American journal of hypertension 1997;10(3):289-96.
1997: Wolfgang Jelkmann; Horst Pagel; T Hellwig; Joachim Fandrey
Effects of antioxidant vitamins on renal and hepatic erythropoietin production.
Kidney international 1997;51(2):497-501.
1997: Joachim Fandrey; Stilla Frede; W Ehleben; T Porwol; Helmut Acker; Wolfgang Jelkmann
Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species.
Kidney international 1997;51(2):492-6.
1997: W Ehleben; T Porwol; Joachim Fandrey; W Kummer; Helmut Acker
Cobalt and desferrioxamine reveal crucial members of the oxygen sensing pathway in HepG2 cells.
Kidney international 1997;51(2):483-91.
1996: J Abel; N Spannbrucker; Joachim Fandrey; Wolfgang Jelkmann
Serum erythropoietin levels in patients with sepsis and septic shock.
European journal of haematology 1996;57(5):359-63.
1996: Wolfgang Schobersberger; G Hoffmann; Joachim Fandrey
Nitric oxide donors suppress erythropoietin production in vitro.
Pflügers Archiv : European journal of physiology 1996;432(6):980-5.
1996: Georg Hoffmann; Wolfgang Schobersberger; Stilla Frede; L Pelzer; Joachim Fandrey; H Wachter; Dietmar Fuchs; J Grote
Neopterin activates transcription factor nuclear factor-kappa B in vascular smooth muscle cells.
FEBS letters 1996;391(1-2):181-4.
1996: Max Gassmann; Joachim Fandrey; S Bichet; Maria Wartenberg; Hugo H Marti; Christian Bauer; Roland H Wenger; Helmut Acker
Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2867-72.
1996: Stilla Frede; Joachim Fandrey; Wolfgang Jelkmann
Interleukin 1 beta and phorbol ester induce tumour necrosis factor alpha production in a hepatic cell line (HepG2).
Pflügers Archiv : European journal of physiology 1996;431(6):923-7.
1996: Nuschin Morakkabati; F Gollnick; Rainer Meyer; Joachim Fandrey; Wolfgang Jelkmann
Erythropoietin induces Ca2+ mobilization and contraction in rat mesangial and aortic smooth muscle cultures.
Experimental hematology 1996;24(2):392-7.
1995: Joachim Fandrey
Hypoxia-inducible gene expression.
Respiration physiology 1995;101(1):1-10.
1995: Eric Metzen; M Wolff; Joachim Fandrey; Wolfgang Jelkmann
Pericellular PO2 and O2 consumption in monolayer cell cultures.
Respiration physiology 1995;100(2):101-6.
1995: Stilla Frede; Joachim Fandrey; Wolfgang Jelkmann
Role of protein kinase C in hepatic erythropoietin synthesis.
Experimental hematology 1995;23(2):96-8.
1994: Joachim Fandrey; A Huwiler; Stilla Frede; J Pfeilschifter; Wolfgang Jelkmann
Distinct signaling pathways mediate phorbol-ester-induced and cytokine-induced inhibition of erythropoietin gene expression.
European journal of biochemistry / FEBS 1994;226(2):335-40.
1994: Joachim Fandrey; Stilla Frede; Wolfgang Jelkmann
Role of hydrogen peroxide in hypoxia-induced erythropoietin production.
The Biochemical journal 1994;303 ( Pt 2)():507-10.
1994: B Brenner; Joachim Fandrey; Wolfgang Jelkmann
Serum immunoreactive erythropoietin in hyper- and hypothyroidism: clinical observations related to cell culture studies.
European journal of haematology 1994;53(1):6-10.
1994: Joachim Fandrey; Stilla Frede; Wolfgang Jelkmann
Oxygen sensing by H2O2-generating heme proteins.
Annals of the New York Academy of Sciences 1994;718():341-3.
1994: Wolfgang Jelkmann; Joachim Fandrey; Stilla Frede; Horst Pagel
Inhibition of erythropoietin production by cytokines. Implications for the anemia involved in inflammatory states.
Annals of the New York Academy of Sciences 1994;718():300-9; discussion 309-11.
1994: Joachim Fandrey; Horst Pagel; Stilla Frede; M Wolff; Wolfgang Jelkmann
Thyroid hormones enhance hypoxia-induced erythropoietin production in vitro.
Experimental hematology 1994;22(3):272-7.
1994: Wolfgang Jelkmann; M Wolff; Joachim Fandrey
Inhibition of erythropoietin production by cytokines and chemotherapy may contribute to the anemia in malignant diseases.
Advances in experimental medicine and biology 1994;345():525-30.
1994: Joachim Fandrey; Stilla Frede; Wolfgang Jelkmann
Oxygen sensing by H2O2-generating heme proteins?
Advances in experimental medicine and biology 1994;361():591-5.
1993: M Wolff; Joachim Fandrey; Wolfgang Jelkmann
Microelectrode measurements of pericellular PO2 in erythropoietin-producing human hepatoma cell cultures.
The American journal of physiology 1993;265(5 Pt 1):C1266-70.
1992: Joachim Fandrey; Wolfgang Jelkmann
[Chemical structure, biotechnical production and clinical use of recombinant erythropoietin].
Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete 1992;47(6):231-8.
1992: Wolfgang Jelkmann; Horst Pagel; M Wolff; Joachim Fandrey
Monokines inhibiting erythropoietin production in human hepatoma cultures and in isolated perfused rat kidneys.
Life sciences 1992;50(4):301-8.
1991: Wolfgang Jelkmann; A Huwiler; Joachim Fandrey; J Pfeilschifter
Inhibition of erythropoietin production by phorbol ester is associated with down-regulation of protein kinase C-alpha isoenzyme in hepatoma cells.
Biochemical and biophysical research communications 1991;179(3):1441-8.
1991: Joachim Fandrey; Wolfgang Jelkmann
Interleukin-1 and tumor necrosis factor-alpha inhibit erythropoietin production in vitro.
Annals of the New York Academy of Sciences 1991;628():250-5.
1991: Joachim Fandrey; PM Rob; Wolfgang Jelkmann
Theophylline and magnesium inhibit the contraction elicited with ciclosporin and angiotensin II in mesangial cell cultures.
Nephron 1991;57(1):94-8.
1990: PM Rob; Joachim Fandrey
[Studies on cultured rat mesangial cells using cyclosporin A and magnesium--is magnesium nephroprotective in cyclosporin A therapy?].
Klinische Wochenschrift 1990;68(16):835-9.
1990: Joachim Fandrey; F P Seydel; Claus-Peter Siegers; Wolfgang Jelkmann
Role of cytochrome P450 in the control of the production of erythropoietin.
Life sciences 1990;47(2):127-34.
1990: Wolfgang Jelkmann; Joachim Fandrey; G Wiedemann
Immunoreactive erythropoietin in the anemia of non-renal chronic diseases.
Biomedica biochimica acta 1990;49(2-3):S265-70.
1989: PM Rob; Joachim Fandrey; Wolfgang Jelkmann
Theophylline: a new concept of nephroprotection in acute cyclosporin A nephrotoxicity?
Klinische Wochenschrift 1989;67(12):648.
1988: Joachim Fandrey; Wolfgang Jelkmann
Prostaglandin E2 and atriopeptin III oppose the contractile effect of angiotensin II in rat kidney mesangial cell cultures.
Prostaglandins 1988;36(2):249-57.