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Bingliang Fang

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
40
Roth, Jack
32
Zhang, Lidong
24
Davis, John
24
Guo, Wei
23
Teraishi, Fuminori
17
Gu, Jian
15
Ji, Lin
15
Wu, Shuhong
12
Swisher, Stephen
11
Zhu, Hongbo
10
Dong, Fengqin
9
Liu, Jinsong
8
Lin, Tongyu
8
Huang, Xuefeng
8
Bouvet, Michael

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Publications

TOP 3
Hu Wenxian; Hofstetter Wayne L; Li Hong; Zhou Yanbin; He Yong; Pataer Abujiang; Wang Li; Xie Keping; Swisher Stephen G; Fang Bingliang
Putative tumor-suppressive function of kruppel-like factor 4 in primary lung carcinoma.
Wei Xiaoli; Guo Wei; Wu Shuhong; Wang Li; Lu Yiling; Xu Bo; Liu Jinsong; Fang Bingliang
Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.
Hu Wenxian; Hofstetter Wayne; Wei Xiaoli; Guo Wei; Zhou Yanbin; Pataer Abujiang; Li Hong; Fang Bingliang; Swisher Stephen G
Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound.

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All Publications

2009: Hu Wenxian; Hofstetter Wayne L; Li Hong; Zhou Yanbin; He Yong; Pataer Abujiang; Wang Li; Xie Keping; Swisher Stephen G; Fang Bingliang
Putative tumor-suppressive function of kruppel-like factor 4 in primary lung carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(18):5688-95.
2009: Wei Xiaoli; Guo Wei; Wu Shuhong; Wang Li; Lu Yiling; Xu Bo; Liu Jinsong; Fang Bingliang
Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.
The Journal of biological chemistry 2009;284(25):16948-55.
2009: Hu Wenxian; Hofstetter Wayne; Wei Xiaoli; Guo Wei; Zhou Yanbin; Pataer Abujiang; Li Hong; Fang Bingliang; Swisher Stephen G
Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound.
The Journal of pharmacology and experimental therapeutics 2009;328(3):866-72.
2009: Guo Wei; Wu Shuhong; Wang Li; Wang Rui-yu; Wei Xiaoli; Liu Jinsong; Fang Bingliang
Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).
Molecular cancer therapeutics 2009;8(2):441-8.
2009: Guo Wei; Fang Bingliang
Potentiation of oncolytic virotherapy with armed shRNA.
Cancer biology & therapy 2009;8(1):92-3.
2008: Guo Wei; Wu Shuhong; Liu Jinsong; Fang Bingliang
Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota.
Cancer research 2008;68(18):7403-8.
2008: Guo Z Sheng; Li Qiang; Bartlett David L; Yang James Y; Fang Bingliang
Gene transfer: the challenge of regulated gene expression.
Trends in molecular medicine 2008;14(9):410-8.
2008: Hu W; Hofstetter W; Guo W; Li H; Pataer A; Peng H H; Guo Z S; Bartlett D L; Lin A; Swisher S G; Fang B
JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase.
Cancer gene therapy 2008;15(9):616-24.
2008: Shamimi-Noori S; Yeow W-S; Ziauddin M F; Xin H; Tran T L N; Xie J; Loehfelm A; Patel P; Yang J; Schrump D S; Fang B L; Nguyen D M
Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway.
Cancer gene therapy 2008;15(6):356-70.
2008: Zhang Xiaochun; Komaki Ritsuko; Wang Li; Fang Bingliang; Chang Joe Y
Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(9):2813-23.
2008: Wagener Matthew; Zhang Xiaochun; Villarreal Humberto G; Levy Larry; Allen Pamela; Shentu Shujun; Fang Bingliang; Krishnan Sunil; Chang Joe Y; Cheung M Rex
Effect of combining anti-epidermal growth factor receptor antibody C225 and radiation on DU145 prostate cancer.
Oncology reports 2008;19(5):1071-7.
2008: Wu Yuanqing; Fang Bingliang; Yang Xiulan Q; Wang Li; Chen Dongning; Krasnykh Victor; Carter Bing Z; Morris Jeffrey S; Shureiqi Imad
Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):886-92.
2008: Zhou Hongyu; Wu Shuhong; Zhai Shumei; Liu Aifeng; Sun Ying; Li Rongshi; Zhang Ying; Ekins Sean; Swaan Peter W; Fang Bingliang; Zhang Bin; Yan Bing
Design, synthesis, cytoselective toxicity, structure-activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells.
Journal of medicinal chemistry 2008;51(5):1242-51.
2008: Guo Wei; Fang Bingliang
Enhancing anti-cancer virotherapy with heat-shock protein-mediated immune response.
Cancer biology & therapy 2008;7(2):196-7.
2007: Hu Wenxian; Davis John J; Zhu Hongbo; Dong Fengqin; Guo Wei; Ang Jian; Peng Henry; Guo Z Sheng; Bartlett David L; Swisher Stephen G; Fang Bingliang
Redirecting adaptive immunity against foreign antigens to tumors for cancer therapy.
Cancer biology & therapy 2007;6(11):1773-9.
2007: Zhu Hongbo; Zhu Yuping; Hu Jingzi; Hu Wenxian; Liao Yongqiang; Zhang Jun; Wang Da; Huang Xuefeng; Fang Bingliang; He Chao
Adenovirus-mediated small hairpin RNA targeting Bcl-XL as therapy for colon cancer.
International journal of cancer. Journal international du cancer 2007;121(6):1366-72.
2007: Deng Wu-Guo; Nishizaki Masahiko; Fang Bingliang; Roth Jack A; Ji Lin
Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells.
Biochemical and biophysical research communications 2007;355(4):993-9.
2007: Hannay J; Davis J J; Yu D; Liu J; Fang B; Pollock R E; Lev D
Isolated limb perfusion: a novel delivery system for wild-type p53 and fiber-modified oncolytic adenoviruses to extremity sarcoma.
Gene therapy 2007;14(8):671-81.
2006: Guo Wei; Fang Bingliang
Dominant Negative RAS as an anticancer agent.
Cancer biology & therapy 2006;5(11):1492-3.
2006: Fang Bingliang
Targeting apoptosis to cancer via hTERT promoter.
Cancer biology & therapy 2006;5(11):1554-5.
2006: Wu S; Guo W; Teraishi F; Pang J; Kaluarachchi K; Zhang L; Davis J; Dong F; Yan B; Fang B
Anticancer activity of 5-benzylidene-2-phenylimino-1, 3-thiazolidin-4-one (BPT) analogs.
Medicinal chemistry (Shariqah (United Arab Emirates)) 2006;2(6):597-605.
2006: Dong Fengqin; Wang Li; Davis John J; Hu Wenxian; Zhang Lidong; Guo Wei; Teraishi Fuminori; Ji Lin; Fang Bingliang
Eliminating established tumor in nu/nu nude mice by a tumor necrosis factor-alpha-related apoptosis-inducing ligand-armed oncolytic adenovirus.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(17):5224-30.
2006: Peng Henry H; Wu Shuhong; Davis John J; Wang Li; Roth Jack A; Marini Frank C; Fang Bingliang
A rapid and efficient method for purification of recombinant adenovirus with arginine-glycine-aspartic acid-modified fibers.
Analytical biochemistry 2006;354(1):140-7.
2006: Davis J J; Wang L; Dong F; Zhang L; Guo W; Teraishi F; Xu K; Ji L; Fang B
Oncolysis and suppression of tumor growth by a GFP-expressing oncolytic adenovirus controlled by an hTERT and CMV hybrid promoter.
Cancer gene therapy 2006;13(7):720-3.
2006: Wu Shuhong; Guo Wei; Fang Bingliang
Development of small-molecule inhibitors of Raf.
Recent patents on anti-infective drug discovery 2006;1(2):241-6.
2006: Teraishi Fuminori; Guo Wei; Zhang Lidong; Dong Fengqing; Davis John J; Sasazuki Takehiko; Shirasawa Senji; Liu Jinsong; Fang Bingliang
Activation of sterile20-like kinase 1 in proteasome inhibitor bortezomib-induced apoptosis in oncogenic K-ras-transformed cells.
Cancer research 2006;66(12):6072-9.
2006: Chang Joe Y; Zhang Xiaochun; Komaki Ritsuko; Cheung Rex; Fang Bingliang
Tumor-specific apoptotic gene targeting overcomes radiation resistance in esophageal adenocarcinoma.
International journal of radiation oncology, biology, physics 2006;64(5):1482-94.
2006: Teraishi Fuminori; Wu Shuhong; Inoue Satoshi; Zhang Lidong; Davis John J; Guo Wei; Dong Fengqin; Fang Bingliang
Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound.
The Prostate 2006;66(4):430-8.
2006: Dong Fengqin; Guo Wei; Zhang Lidong; Wu Shuhong; Teraishi Fuminori; Davis John J; Fang Bingliang
Downregulation of XIAP and induction of apoptosis by the synthetic cyclin-dependent kinase inhibitor GW8510 in non-small cell lung cancer cells.
Cancer biology & therapy 2006;5(2):165-70.
2006: Chen Bin; He Chao; Lao Wei-feng; Huang Xue-feng; Fang Bing-liang
[Activity of the TNF-related apoptosis-inducing ligand gene expressed from the hTERT promoter on colon cancer cell line HT-29]
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 2006;35(1):45-9.
2006: Guo W; Zhu H; Zhang L; Davis J; Teraishi F; Roth J A; Stephens C; Fueyo J; Jiang H; Conrad C; Fang B
Combination effect of oncolytic adenovirotherapy and TRAIL gene therapy in syngeneic murine breast cancer models.
Cancer gene therapy 2006;13(1):82-90.
2005: Teraishi Fuminori; Zhang Lidong; Guo Wei; Dong Fengqin; Davis John J; Lin Anning; Fang Bingliang
Activation of c-Jun NH2-terminal kinase is required for gemcitabine's cytotoxic effect in human lung cancer H1299 cells.
FEBS letters 2005;579(29):6681-7.
2005: Davis J J; Fang B
Oncolytic virotherapy for cancer treatment: challenges and solutions.
The journal of gene medicine 2005;7(11):1380-9.
2005: Teraishi F; Wu S; Sasaki J; Zhang L; Davis J J; Guo W; Dong F; Fang B
JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
Cellular and molecular life sciences : CMLS 2005;62(19-20):2382-9.
2005: Zhang Xiaochun; Cheung Rex Min; Komaki Ritsuko; Fang Bingliang; Chang Joe Y
Radiotherapy sensitization by tumor-specific TRAIL gene targeting improves survival of mice bearing human non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(18):6657-68.
2005: Zhu Hongbo; Guo Wei; Zhang Lidong; Wu Shuhong; Teraishi Fuminori; Davis John J; Dong Fengqin; Fang Bingliang
Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Cancer biology & therapy 2005;4(7):781-6.
2005: Teraishi Fuminori; Wu Shuhong; Zhang Lidong; Guo Wei; Davis John J; Dong Fengqin; Fang Bingliang
Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
Cancer research 2005;65(14):6380-7.
2005: Teraishi Fuminori; Wu Shuhong; Sasaki Jiichiro; Zhang Lidong; Zhu Hong-Bo; Davis John J; Fang Bingliang
P-glycoprotein-independent apoptosis induction by a novel synthetic compound, MMPT [5-[(4-methylphenyl)methylene]-2-(phenylamino)-4(5H)-thiazolone].
The Journal of pharmacology and experimental therapeutics 2005;314(1):355-62.
2005: Zhu Hongbo; Zhang Lidong; Dong Fengqin; Guo Wei; Wu Shuhong; Teraishi Fuminori; Davis John J; Chiao Paul J; Fang Bingliang
Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
Oncogene 2005;24(31):4993-9.
2005: Zhang Lidong; Zhu Hongbo; Teraishi Fuminori; Davis John J; Guo Wei; Fan Zhen; Fang Bingliang
Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line.
Neoplasia (New York, N.Y.) 2005;7(6):594-602.
2005: Pan Jingxuan; Huang Huizhi; Sun Lily; Fang Bingliang; Yeung Sai-Ching Jim
Bcl-2-associated X protein is the main mediator of manumycin a-induced apoptosis in anaplastic thyroid cancer cells.
The Journal of clinical endocrinology and metabolism 2005;90(6):3583-91.
2005: Jacob Dietmar; Schumacher Guido; Bahra Marcus; Davis John; Zhu Hong-Bo; Zhang Li-Dong; Teraishi Fuminori; Neuhaus Peter; Fang Bing-Liang
Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells.
World journal of gastroenterology : WJG 2005;11(17):2552-6.
2005: Zhu Hongbo; Guo Wei; Zhang Lidong; Davis John J; Wu Shuhong; Teraishi Fuminori; Cao Xiaobo; Smythe W Roy; Fang Bingliang
Enhancing TRAIL-induced apoptosis by Bcl-X(L) siRNA.
Cancer biology & therapy 2005;4(4):393-7.
2005: Zhu Hongbo; Guo Wei; Zhang Lidong; Davis John J; Teraishi Fuminori; Wu Shuhong; Cao Xiaobo; Daniel Jonathan; Smythe W Roy; Fang Bingliang
Bcl-XL small interfering RNA suppresses the proliferation of 5-fluorouracil-resistant human colon cancer cells.
Molecular cancer therapeutics 2005;4(3):451-6.
2005: Zhang Lidong; Fang Bingliang
Mechanisms of resistance to TRAIL-induced apoptosis in cancer.
Cancer gene therapy 2005;12(3):228-37.
2005: Jacob Dietmar; Davis John J; Zhang Lidong; Zhu Hongbo; Teraishi Fuminori; Fang Bingliang
Suppression of pancreatic tumor growth in the liver by systemic administration of the TRAIL gene driven by the hTERT promoter.
Cancer gene therapy 2005;12(2):109-15.
2004: Jacob D; Davis J; Schumacher G; Bahra M; Neuhaus P; Fang B
[Adenoviral vector expressing the TRAIL gene driven by the hTERT promoter]
Zeitschrift für Gastroenterologie 2004;42(12):1363-70.
2004: Reddy Rishindra M; Tsai Wilson S; Ziauddin M Firdos; Zuo Jingtong; Cole George W; Maxhimer Justin B; Fang BingLiang; Schrump David S; Nguyen Dao M
Cisplatin enhances apoptosis induced by a tumor-selective adenovirus expressing tumor necrosis factor-related apoptosis-inducing ligand.
The Journal of thoracic and cardiovascular surgery 2004;128(6):883-91.
2004: Han J; Goldstein L A; Gastman B R; Rabinovitz A; Wang G-Q; Fang B; Rabinowich H
Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(10):1671-80.
2004: Jacob Dietmar; Bahra Marcus; Schumacher Guido; Neuhaus Peter; Fang Bingliang
Gene therapy in colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter.
Anticancer research 2004;24(5A):3075-9.
2004: Nishizaki Masahiko; Sasaki Ji-Ichiro; Fang Bingliang; Atkinson Edward N; Minna John D; Roth Jack A; Ji Lin
Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells.
Cancer research 2004;64(16):5745-52.
2004: Zhu Hongbo; Zhang Lidong; Wu Shuhong; Teraishi Fuminori; Davis John J; Jacob Dietmar; Fang Bingliang
Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK.
Oncogene 2004;23(29):4984-92.
2004: Jacob Dietmar; Davis John; Zhu Hongbo; Zhang Lidong; Teraishi Fuminori; Wu Shuhong; Marini Frank C; Fang Bingliang
Suppressing orthotopic pancreatic tumor growth with a fiber-modified adenovector expressing the TRAIL gene from the human telomerase reverse transcriptase promoter.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3535-41.
2004: Zhu Hongbo; Zhang Lidong; Huang Xuefeng; Davis John J; Jacob Dietmar A; Teraishi Fuminori; Chiao Paul; Fang Bingliang
Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(5):666-73.
2004: Tsunemitsu Y; Kagawa S; Tokunaga N; Otani S; Umeoka T; Roth J A; Fang B; Tanaka N; Fujiwara T
Molecular therapy for peritoneal dissemination of xenotransplanted human MKN-45 gastric cancer cells with adenovirus mediated Bax gene transfer.
Gut 2004;53(4):554-60.
2004: Honda Tsuyoshi; Coppola Simona; Ghibelli Lina; Cho Song H; Kagawa Shunsuke; Spurgers Kevin B; Brisbay Shawn M; Roth Jack A; Meyn Raymond E; Fang Bingliang; McDonnell Timothy J
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.
Cancer gene therapy 2004;11(4):249-55.
2004: He Chao; Lao Wei-Feng; Hu Xiao-Tong; Xu Xiang-Ming; Xu Jing; Fang Bing-Liang
Anti-liver cancer activity of TNF-related apoptosis-inducing ligand gene and its bystander effects.
World journal of gastroenterology : WJG 2004;10(5):654-9.
2004: Zhang Lidong; Zhu Hongbo; Davis John J; Jacob Dietmar; Wu Shuhong; Teraishi Fuminori; Gutierrez Angelica; Wang Yibin; Fang Bingliang
Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death.
Cancer biology & therapy 2004;3(3):296-301.
2004: Wu Shuhong; Zhu Hongbo; Gu Jian; Zhang Lidong; Teraishi Fuminori; Davis John J; Jacob Dietmar A; Fang Bingliang
Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.
Cancer research 2004;64(3):1110-3.
2004: Gu Jian; Zhang Lidong; Swisher Stephen G; Liu Jinsong; Roth Jack A; Fang Bingliang
Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis.
Oncogene 2004;23(6):1300-7.
2003: Fang Bingliang; Roth Jack A
The role of gene therapy in combined modality treatment strategies for cancer.
Current opinion in molecular therapeutics 2003;5(5):475-82.
2003: Lin Tongyu; Gu Jian; Zhang Lidong; Davis John J; Huang Xuefeng; Cabbini Giovanni; Ji Lin; Fang Bingliang
Enhancing adenovirus-mediated gene transfer in vitro and in vivo by addition of protamine and hydrocortisone.
The journal of gene medicine 2003;5(10):868-75.
2003: Lin Tongyu; Zhang Lidong; Davis John; Gu Jian; Nishizaki Masahiko; Ji Lin; Roth Jack A; Xiong Momiao; Fang Bingliang
Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(3):441-8.
2003: Yang Gong; Thompson Jennifer Anne; Fang Bingliang; Liu Jinsong
Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumorgrowth in a model of human ovarian cancer.
Oncogene 2003;22(36):5694-701.
2003: Katz Matthew H; Spivack Daniel E; Takimoto Shinako; Fang Bingliang; Burton Douglas W; Moossa A R; Hoffman Robert M; Bouvet Michael
Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-related apoptosis-inducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter.
Annals of surgical oncology 2003;10(7):762-72.
2003: Fang Bingliang; Roth Jack A
Tumor-suppressing gene therapy.
Cancer biology & therapy 2003;2(4 Suppl 1):S115-21.
2003: Gu Jian; Fang Bingliang
Telomerase promoter-driven cancer gene therapy.
Cancer biology & therapy 2003;2(4 Suppl 1):S64-70.
2003: Huang Xuefeng; Lin Tongyu; Gu Jian; Zhang Lidong; Roth Jack A; Liu Jinsong; Fang Bingliang
Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene.
International journal of oncology 2003;22(6):1241-5.
2003: Xu Xiang-Ming; He Chao; Hu Xiao-Tong; Fang Bing-Liang
Tumor necrosis factor-related apoptosis-inducing ligand gene on human colorectal cancer cell line HT29.
World journal of gastroenterology : WJG 2003;9(5):965-9.
2003: Krieg A; Krieg T; Wenzel M; Schmitt M; Ramp U; Fang B; Gabbert H E; Gerharz C D; Mahotka C
TRAIL-beta and TRAIL-gamma: two novel splice variants of the human TNF-related apoptosis-inducing ligand (TRAIL) without apoptotic potential.
British journal of cancer 2003;88(6):918-27.
2002: Bao Jia-Ju; Le Xiao-Feng; Wang Rui-Yu; Yuan Jiuhong; Wang Lin; Atkinson Edward N; LaPushin Ruth; Andreeff Michael; Fang Bingliang; Yu Yinhua; Bast Robert C
Reexpression of the tumor suppressor gene ARHI induces apoptosis in ovarian and breast cancer cells through a caspase-independent calpain-dependent pathway.
Cancer research 2002;62(24):7264-72.
2002: Lin Tongyu; Huang Xuefeng; Gu Jian; Zhang Lidong; Roth Jack A; Xiong Momiao; Curley Steven A; Yu Yinhua; Hunt Kelly K; Fang Bingliang
Long-term tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells.
Oncogene 2002;21(52):8020-8.
2002: Huang X; Lin T; Gu J; Zhang L; Roth J A; Stephens L C; Yu Y; Liu J; Fang B
Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft.
Gene therapy 2002;9(20):1379-86.
2002: Zhang L; Gu J; Lin T; Huang X; Roth J A; Fang B
Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line.
Gene therapy 2002;9(18):1262-70.
2002: Pirocanac Elissa C; Nassirpour Rounak; Yang Meng; Wang Jinwei; Nardin Stephanie R; Gu Jian; Fang Bingliang; Moossa A R; Hoffman Robert M; Bouvet Michael
Bax-induction gene therapy of pancreatic cancer.
The Journal of surgical research 2002;106(2):346-51.
2002: Gu Jian; Zhang Lidong; Huang Xuefeng; Lin Tongyu; Yin Min; Xu Kai; Ji Lin; Roth Jack A; Fang Bingliang
A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo.
Oncogene 2002;21(31):4757-64.
2002: Lin Tongyu; Gu Jian; Zhang Lidong; Huang Xuefeng; Stephens L Clifton; Curley Steven A; Fang Bingliang
Targeted expression of green fluorescent protein/tumor necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumor activity without toxic effects on primary human hepatocytes.
Cancer research 2002;62(13):3620-5.
2002: Tanyi Janos L; Lapushin Ruth; Eder Astrid; Auersperg Nelly; Tabassam Fazal H; Roth Jack A; Gu Jian; Fang Binglian; Mills Gordon B; Wolf Judith
Identification of tissue- and cancer-selective promoters for the introduction of genes into human ovarian cancer cells.
Gynecologic oncology 2002;85(3):451-8.
2002: Nutt Leta K; Chandra Joya; Pataer Abujiang; Fang Bingliang; Roth Jack A; Swisher Stephen G; O'Neil Roger G; McConkey David J
Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis.
The Journal of biological chemistry 2002;277(23):20301-8.
2002: Ji Lin; Nishizaki Masahiko; Gao Boning; Burbee David; Kondo Masashi; Kamibayashi Craig; Xu Kai; Yen Nancy; Atkinson E Neely; Fang Bingliang; Lerman Michael I; Roth Jack A; Minna John D
Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo.
Cancer research 2002;62(9):2715-20.
2002: Honda Tsuyoshi; Kagawa Shunsuke; Spurgers Kevin B; Gjertsen Bjorn T; Roth Jack A; Fang Bingliang; Lowe Stephanie L; Norris James S; Meyn Raymond E; McDonnell Timothy J
A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity.
Cancer biology & therapy 2002;1(2):163-7.
2002: He Chao; Hu Xiaotong; Xu Xiangming; Fang Bingliang
[Action of apoptosis-induced ligand gene in relation to tumor necrosis factor on human colon cancer cell line HT29]
Zhonghua zhong liu za zhi [Chinese journal of oncology] 2002;24(2):133-6.
2002: Nikitina E Y; Chada S; Muro-Cacho C; Fang B; Zhang R; Roth J A; Gabrilovich D I
An effective immunization and cancer treatment with activated dendritic cells transduced with full-length wild-type p53.
Gene therapy 2002;9(5):345-52.
2002: Nutt Leta K; Pataer Abujiang; Pahler Jessica; Fang Bingliang; Roth Jack; McConkey David J; Swisher Stephen G
Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores.
The Journal of biological chemistry 2002;277(11):9219-25.
2002: Gu J; Andreeff M; Roth J A; Fang B
hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity.
Gene therapy 2002;9(1):30-7.
2002: Adachi Yoshiaki; Chandrasekar Nirmala; Kin Yoshiaki; Lakka Sajani S; Mohanam Sanjeeva; Yanamandra Niranjan; Mohan Pamarthi M; Fuller Gregory N; Fang Bingliang; Fueyo Juan; Dinh Dzung H; Olivero William C; Tamiya Takashi; Ohmoto Takashi; Kyritsis Anthanassios P; Rao Jasti S
Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences.
Oncogene 2002;21(1):87-95.
2001: Li Z; Xia W; Fang B; Yan D H
Targeting HER-2/neu-overexpressing breast cancer cells by an antisense iron responsive element-directed gene expression.
Cancer letters 2001;174(2):151-8.
2001: Wang G Q; Wieckowski E; Goldstein L A; Gastman B R; Rabinovitz A; Gambotto A; Li S; Fang B; Yin X M; Rabinowich H
Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells.
The Journal of experimental medicine 2001;194(9):1325-37.
2001: Andriani F; Nan B; Yu J; Li X; Weigel N L; McPhaul M J; Kasper S; Kagawa S; Fang B; Matusik R J; Denner L; Marcelli M
Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells.
Journal of the National Cancer Institute 2001;93(17):1314-24.
2001: Wang G Q; Gastman B R; Wieckowski E; Goldstein L A; Gambotto A; Kim T H; Fang B; Rabinovitz A; Yin X M; Rabinowich H
A role for mitochondrial Bak in apoptotic response to anticancer drugs.
The Journal of biological chemistry 2001;276(36):34307-17.
2001: Mohiuddin I; Cao X; Fang B; Nishizaki M; Smythe W R
Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma.
Cancer gene therapy 2001;8(8):547-54.
2001: Aprelikova O; Pace A J; Fang B; Koller B H; Liu E T
BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells.
The Journal of biological chemistry 2001;276(28):25647-50.
2001: Kagawa S; Gu J; Honda T; McDonnell T J; Swisher S G; Roth J A; Fang B
Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1474-80.
2001: Kagawa S; He C; Gu J; Koch P; Rha S J; Roth J A; Curley S A; Stephens L C; Fang B
Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene.
Cancer research 2001;61(8):3330-8.
2001: Koch P E; Guo Z S; Kagawa S; Gu J; Roth J A; Fang B
Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(3):278-83.
2001: Li X; Marani M; Yu J; Nan B; Roth J A; Kagawa S; Fang B; Denner L; Marcelli M
Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer.
Cancer research 2001;61(1):186-91.
2001: Pataer A; Smythe W R; Yu R; Fang B; McDonnell T; Roth J A; Swisher S G
Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines.
The Journal of thoracic and cardiovascular surgery 2001;121(1):61-7.
2000: Gu J; Kagawa S; Takakura M; Kyo S; Inoue M; Roth J A; Fang B
Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers.
Cancer research 2000;60(19):5359-64.
2000: Sueoka N; Lee H Y; Wiehle S; Cristiano R J; Fang B; Ji L; Roth J A; Hong W K; Cohen P; Kurie J M
Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells.
Oncogene 2000;19(38):4432-6.
2000: Sueoka N; Lee H Y; Walsh G L; Fang B; Ji L; Roth J A; LaPushin R; Hong W K; Cohen P; Kurie J M
Insulin-like growth factor binding protein-6 inhibits the growth of human bronchial epithelial cells and increases in abundance with all-trans-retinoic acid treatment.
American journal of respiratory cell and molecular biology 2000;23(3):297-303.
2000: Yen N; Ioannides C G; Xu K; Swisher S G; Lawrence D D; Kemp B L; El-Naggar A K; Cristiano R J; Fang B; Glisson B S; Hong W K; Khuri F R; Kurie J M; Lee J J; Lee J S; Merritt J A; Mukhopadhyay T; Nesbitt J C; Nguyen D; Perez-Soler R; Pisters K M; Putnam J B; Schrump D S; Shin D M; Walsh G L; Roth J A
Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53).
Cancer gene therapy 2000;7(4):530-6.
2000: Kagawa S; Gu J; Swisher S G; Ji L; Roth J A; Lai D; Stephens L C; Fang B
Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines.
Cancer research 2000;60(5):1157-61.
2000: Pataer A; Fang B; Yu R; Kagawa S; Hunt K K; McDonnell T J; Roth J A; Swisher S G
Adenoviral Bak overexpression mediates caspase-dependent tumor killing.
Cancer research 2000;60(4):788-92.
2000: Kagawa S; Pearson S A; Ji L; Xu K; McDonnell T J; Swisher S G; Roth J A; Fang B
A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax.
Gene therapy 2000;7(1):75-9.
1999: Pearson A S; Koch P E; Atkinson N; Xiong M; Finberg R W; Roth J A; Fang B
Factors limiting adenovirus-mediated gene transfer into human lung and pancreatic cancer cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(12):4208-13.
1999: Aprelikova O N; Fang B S; Meissner E G; Cotter S; Campbell M; Kuthiala A; Bessho M; Jensen R A; Liu E T
BRCA1-associated growth arrest is RB-dependent.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):11866-71.
1999: Mohan P M; Chintala S K; Mohanam S; Gladson C L; Kim E S; Gokaslan Z L; Lakka S S; Roth J A; Fang B; Sawaya R; Kyritsis A P; Rao J S
Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth.
Cancer research 1999;59(14):3369-73.
1999: Ji L; Fang B; Yen N; Fong K; Minna J D; Roth J A
Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression.
Cancer research 1999;59(14):3333-9.
1999: Ji L; Fang B; Roth J A
A rapid, sensitive, and nonradioactive method for assay of FHIT Ap3A hydrolase activity by fluorescence thin-layer chromatographic image analysis.
Analytical biochemistry 1999;271(1):114-6.
1999: Chen Y Q; Hsieh J T; Yao F; Fang B; Pong R C; Cipriano S C; Krepulat F
Induction of apoptosis and G2/M cell cycle arrest by DCC.
Oncogene 1999;18(17):2747-54.
1999: Ji L; Bouvet M; Price R E; Roth J A; Fang B
Reduced toxicity, attenuated immunogenicity and efficient mediation of human p53 gene expression in vivo by an adenovirus vector with deleted E1-E3 and inactivated E4 by GAL4-TATA promoter replacement.
Gene therapy 1999;6(3):393-402.
1998: Bouvet M; Bold R J; Lee J; Evans D B; Abbruzzese J L; Chiao P J; McConkey D J; Chandra J; Chada S; Fang B; Roth J A
Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments]
Annals of surgical oncology 1998;5(8):681-8.
1998: Fang B; Xu B; Koch P; Roth J A
Intercellular trafficking of VP22-GFP fusion proteins is not observed in cultured mammalian cells.
Gene therapy 1998;5(10):1420-4.
1998: Bouvet M; Ellis L M; Nishizaki M; Fujiwara T; Liu W; Bucana C D; Fang B; Lee J J; Roth J A
Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer.
Cancer research 1998;58(11):2288-92.
1998: Bouvet M; Fang B; Ekmekcioglu S; Ji L; Bucana C D; Hamada K; Grimm E A; Roth J A
Suppression of the immune response to an adenovirus vector and enhancement of intratumoral transgene expression by low-dose etoposide.
Gene therapy 1998;5(2):189-95.
1998: Fang B; Ji L; Bouvet M; Roth J A
Evaluation of GAL4/TATA in vivo. Induction of transgene expression by adenovirally mediated gene codelivery.
The Journal of biological chemistry 1998;273(9):4972-5.
1997: Fang B; Koch P; Bouvet M; Ji L; Roth J A
A packaging system for SV40 vectors without viral coding sequences.
Analytical biochemistry 1997;254(1):139-43.
1997: Fang B; Koch P; Roth J A
Diminishing adenovirus gene expression and viral replication by promoter replacement.
Journal of virology 1997;71(6):4798-803.
1996: Fang B; Wang H; Gordon G; Bellinger D A; Read M S; Brinkhous K M; Woo S L; Eisensmith R C
Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs.
Gene therapy 1996;3(3):217-22.
1995: Fang B; Eisensmith R C; Wang H; Kay M A; Cross R E; Landen C N; Gordon G; Bellinger D A; Read M S; Hu P C
Gene therapy for hemophilia B: host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression.
Human gene therapy 1995;6(8):1039-44.
1995: Li J; Fang B; Eisensmith R C; Li X H; Nasonkin I; Lin-Lee Y C; Mims M P; Hughes A; Montgomery C D; Roberts J D
In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.
The Journal of clinical investigation 1995;95(2):768-73.
1994: Fang B; Eisensmith R C; Li X H; Finegold M J; Shedlovsky A; Dove W; Woo S L
Gene therapy for phenylketonuria: phenotypic correction in a genetically deficient mouse model by adenovirus-mediated hepatic gene transfer.
Gene therapy 1994;1(4):247-54.
1994: Kay M A; Landen C N; Rothenberg S R; Taylor L A; Leland F; Wiehle S; Fang B; Bellinger D; Finegold M; Thompson A R
In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2353-7.
1989: Singh S; Fritze G; Fang B L; Harada S; Paik Y K; Eckey R; Agarwal D P; Goedde H W
Inheritance of mitochondrial aldehyde dehydrogenase: genotyping in Chinese, Japanese and South Korean families reveals dominance of the mutant allele.
Human genetics 1989;83(2):119-21.

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