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Edward Abraham

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Neutrophil Activation

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Co-Publications
Name
24
Shenkar, Robert
22
Arcaroli, John
15
Park, Jong Sung
14
Liu, Gang
13
Strassheim, Derek
12
Tsuruta, Yuko
10
Lorne, Emmanuel
10
Dinarello, Charles
9
He, Qianbin
9
Laterre, Pierre-François
9
Mitra, Sanchayita
9
Opal, Steven
8
Zmijewski, Jaroslaw
7
Yum, Ho-Kee
7
O'Brien, James

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Publications

TOP 3
Liu Gang; Friggeri Arnaud; Yang Yanping; Park Young-Jun; Tsuruta Yuko; Abraham Edward
miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses.
Lorne Emmanuel; Zhao Xia; Zmijewski Jaroslaw W; Liu Gang; Park Young-Jun; Tsuruta Yuko; Abraham Edward
Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury.
Peltz Erik D; Moore Ernest E; Eckels Phillip C; Damle Sagar S; Tsuruta Yuko; Johnson Jeffrey L; Sauaia Angela; Silliman Christopher C; Banerjee Anirban; Abraham Edward
HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans.

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All Publications

2009: Liu Gang; Friggeri Arnaud; Yang Yanping; Park Young-Jun; Tsuruta Yuko; Abraham Edward
miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15819-24.
2009: Lorne Emmanuel; Zhao Xia; Zmijewski Jaroslaw W; Liu Gang; Park Young-Jun; Tsuruta Yuko; Abraham Edward
Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury.
American journal of respiratory cell and molecular biology 2009;41(2):237-45.
2009: Peltz Erik D; Moore Ernest E; Eckels Phillip C; Damle Sagar S; Tsuruta Yuko; Johnson Jeffrey L; Sauaia Angela; Silliman Christopher C; Banerjee Anirban; Abraham Edward
HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans.
Shock (Augusta, Ga.) 2009;32(1):17-22.
2009: Park Young-Jun; Liu Gang; Tsuruta Yuko; Lorne Emmanuel; Abraham Edward
Participation of the urokinase receptor in neutrophil efferocytosis.
Blood 2009;114(4):860-70.
2009: Abraham Edward
Anticoagulants for acute lung injury: barking up the wrong tree.
Critical care medicine 2009;37(6):2100-1.
2009: Liu Gang; Park Young-Jun; Tsuruta Yuko; Lorne Emmanuel; Abraham Edward
p53 Attenuates lipopolysaccharide-induced NF-kappaB activation and acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):5063-71.
2009: Zmijewski Jaroslaw W; Lorne Emmanuel; Banerjee Sami; Abraham Edward
Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.
American journal of physiology. Lung cellular and molecular physiology 2009;296(4):L624-34.
2009: Zmijewski Jaroslaw W; Lorne Emmanuel; Zhao Xia; Tsuruta Yuko; Sha Yonggang; Liu Gang; Abraham Edward
Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury.
American journal of respiratory and critical care medicine 2009;179(8):694-704.
2009: Song Weifeng; Liu Gang; Bosworth Charles A; Walker John R; Megaw George A; Lazrak Ahmed; Abraham Edward; Sullender Wayne M; Matalon Sadis
Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase.
The Journal of biological chemistry 2009;284(11):7294-306.
2009: Bhandary Yashodhar P; Velusamy Thirunavukkarasu; Shetty Praveenkumar; Shetty Rashmi S; Idell Steven; Cines Douglas B; Jain Deepika; Bdeir Khalil; Abraham Edward; Tsuruta Yuko; Shetty Sreerama
Post-transcriptional regulation of urokinase-type plasminogen activator receptor expression in lipopolysaccharide-induced acute lung injury.
American journal of respiratory and critical care medicine 2009;179(4):288-98.
2009: Abraham Edward
Better infrastructure: industry-academia partnerships--a marriage of convenience?
Critical care medicine 2009;37(1 Suppl):S159-64.
2009: Arcaroli John J; Hokanson John E; Abraham Edward; Geraci Mark; Murphy James R; Bowler Russell P; Dinarello Charles A; Silveira Lori; Sankoff Jeff; Heyland Daren; Wischmeyer Paul; Crapo James D
Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality.
American journal of respiratory and critical care medicine 2009;179(2):105-12.
2008: Abraham Edward; Adler Kenneth B; Shapiro Steven D; Leff Alan R
The ATS journals' policy on image manipulation.
Proceedings of the American Thoracic Society 2008;5(9):869.
2008: Abraham Edward; Adler Kenneth B; Shapiro Steven D; Leff Alan R
The ATS Journals' policy on image manipulation.
American journal of respiratory cell and molecular biology 2008;39(5):499.
2008: Rowe Steven M; Jackson Patricia L; Liu Gang; Hardison Mathew; Livraghi Alessandra; Solomon G Martin; McQuaid D Brent; Noerager Brett D; Gaggar Amit; Clancy J P; O'Neal Wanda; Sorscher Eric J; Abraham Edward; Blalock J Edwin
Potential role of high-mobility group box 1 in cystic fibrosis airway disease.
American journal of respiratory and critical care medicine 2008;178(8):822-31.
2008: Liu Gang; Wang Jing; Park Young-Jun; Tsuruta Yuko; Lorne Emmanuel F; Zhao Xia; Abraham Edward
High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4240-6.
2008: Rubenfeld Gordon D; Abraham Edward
When is a negative phase II trial truly negative?
American journal of respiratory and critical care medicine 2008;178(6):554-5.
2008: Zhao Xia; Zmijewski Jaroslaw W; Lorne Emmanuel; Liu Gang; Park Young-Jun; Tsuruta Yuko; Abraham Edward
Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.
American journal of physiology. Lung cellular and molecular physiology 2008;295(3):L497-504.
2008: Park Young-Jun; Liu Gang; Lorne Emmanuel F; Zhao Xia; Wang Jing; Tsuruta Yuko; Zmijewski Jaroslaw; Abraham Edward
PAI-1 inhibits neutrophil efferocytosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11784-9.
2008: Zmijewski Jaroslaw W; Lorne Emmanuel; Zhao Xia; Tsuruta Yuko; Sha Yonggang; Liu Gang; Siegal Gene P; Abraham Edward
Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury.
American journal of respiratory and critical care medicine 2008;178(2):168-79.
2008: Liu Gang; Park Young-Jun; Abraham Edward
Interleukin-1 receptor-associated kinase (IRAK) -1-mediated NF-kappaB activation requires cytosolic and nuclear activity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(7):2285-96.
2008: Lorne Emmanuel; Zmijewski Jaroslaw W; Zhao Xia; Liu Gang; Tsuruta Yuko; Park Young-Jun; Dupont Hervé; Abraham Edward
Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production.
American journal of physiology. Cell physiology 2008;294(4):C985-93.
2008: Sha Yonggang; Zmijewski Jaroslaw; Xu Zhiwei; Abraham Edward
HMGB1 develops enhanced proinflammatory activity by binding to cytokines.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2531-7.
2008: Arcaroli John; Sankoff Jeff; Liu Nianjun; Allison David B; Maloney James; Abraham Edward
Association between urokinase haplotypes and outcome from infection-associated acute lung injury.
Intensive care medicine 2008;34(2):300-7.
2008: O'Brien James M; Ali Naeem A; Abraham Edward
Year in review 2007: Critical Care--multiple organ failure and sepsis.
Critical care (London, England) 2008;12(5):228.
2008: Laterre Pierre-François; Macias William L; Janes Jonathan; Williams Mark D; Nelson David R; Girbes Amand R J; Dhainaut Jean-François; Abraham Edward
Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis.
Critical care (London, England) 2008;12(5):R117.
2007: O'Brien James M; Ali Naeem A; Aberegg Scott K; Abraham Edward
Sepsis.
The American journal of medicine 2007;120(12):1012-22.
2007: Jaekal Jun; Abraham Edward; Azam Tania; Netea Mihai G; Dinarello Charles A; Lim Jong-Seok; Yang Young; Yoon Do-Young; Kim Soo-Hyun
Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level.
Journal of microbiology and biotechnology 2007;17(11):1862-7.
2007: Tsuruta Yuko; Park Young-Jun; Siegal Gene P; Liu Gang; Abraham Edward
Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):7079-86.
2007: Abraham Edward; Singer Mervyn
Mechanisms of sepsis-induced organ dysfunction.
Critical care medicine 2007;35(10):2408-16.
2007: Silva Eliezer; Arcaroli John; He Qianbin; Svetkauskaite Daiva; Coldren Christopher; Nick Jerry A; Poch Katie; Park Jong Sung; Banerjee Anirban; Abraham Edward
HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury.
Intensive care medicine 2007;33(10):1829-39.
2007: Liu Gang; Tsuruta Yuko; Gao Zhiqian; Park Young-Jun; Abraham Edward
Variant IL-1 receptor-associated kinase-1 mediates increased NF-kappa B activity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):4125-34.
2007: Zmijewski Jaroslaw W; Zhao Xia; Xu Zhiwei; Abraham Edward
Exposure to hydrogen peroxide diminishes NF-kappaB activation, IkappaB-alpha degradation, and proteasome activity in neutrophils.
American journal of physiology. Cell physiology 2007;293(1):C255-66.
2007: Laterre Pierre-Francois; Nelson David R; Macias William; Abraham Edward; Sashegyi Andreas; Williams Mark D; Levy Mitchell; Levi Marcel; Utterback Barbara; Vincent Jean-Louis
International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: 28-day survival and safety.
Journal of critical care 2007;22(2):142-52.
2007: Laterre Pierre-Francois; Abraham Edward; Janes Jonathan M; Trzaskoma Benjamin L; Correll Nancy L; Booth Frank V
ADDRESS (ADministration of DRotrecogin alfa [activated] in Early stage Severe Sepsis) long-term follow-up: one-year safety and efficacy evaluation.
Critical care medicine 2007;35(6):1457-63.
2007: Richeldi Luca; Abraham Edward
Identifying patients with idiopathic pulmonary fibrosis: quality or quantity?
American journal of respiratory and critical care medicine 2007;175(10):976-7.
2007: Abraham Edward
Glucose-6-phosphate dehydrogenase and sepsis: the jury is still out.
Critical care medicine 2007;35(2):655-6.
2006: Coldren Christopher D; Nick Jerry A; Poch Katie R; Woolum Malcolm D; Fouty Brian W; O'Brien James M; Gruber Michael P; Zamora Martin R; Svetkauskaite Daiva; Richter Don A; He Qianbin; Park Jong Sung; Overdier Katherine H; Abraham Edward; Geraci Mark W
Functional and genomic changes induced by alveolar transmigration in human neutrophils.
American journal of physiology. Lung cellular and molecular physiology 2006;291(6):L1267-76.
2006: Wang Xue-Qing; Bdeir Khalil; Yarovoi Sergei; Cines Douglas B; Fang Wenfeng; Abraham Edward
Involvement of the urokinase kringle domain in lipopolysaccharide-induced acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5550-7.
2006: Suda Koichi; Kitagawa Yuko; Ozawa Soji; Saikawa Yoshiro; Ueda Masakazu; Ebina Masahito; Yamada Shingo; Hashimoto Satoru; Fukata Shinji; Abraham Edward; Maruyama Ikuro; Kitajima Masaki; Ishizaka Akitoshi
Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis.
World journal of surgery 2006;30(9):1755-62.
2006: Mitra Sanchayita; Abraham Edward
Participation of superoxide in neutrophil activation and cytokine production.
Biochimica et biophysica acta 2006;1762(8):732-41.
2006: Ogawa Eileen N; Ishizaka Akitoshi; Tasaka Sadatomo; Koh Hidefumi; Ueno Hiroshi; Amaya Fumimasa; Ebina Masahito; Yamada Shingo; Funakoshi Yosuke; Soejima Junko; Moriyama Kiyoshi; Kotani Toru; Hashimoto Satoru; Morisaki Hiroshi; Abraham Edward; Takeda Junzo
Contribution of high-mobility group box-1 to the development of ventilator-induced lung injury.
American journal of respiratory and critical care medicine 2006;174(4):400-7.
2006: Nguyen H Bryant; Rivers Emanuel P; Abrahamian Fredrick M; Moran Gregory J; Abraham Edward; Trzeciak Stephen; Huang David T; Osborn Tiffany; Stevens Dennis; Talan David A;
Severe sepsis and septic shock: review of the literature and emergency department management guidelines.
Annals of emergency medicine 2006;48(1):28-54.
2006: Abraham Edward; Nick Jerry A; Azam Tania; Kim Soo Hyun; Mira Jean-Paul; Svetkauskaite Daiva; He Qianbin; Zamora Marty; Murphy James; Park Jong Sung; Overdier Katherine; Dinarello Charles A
Peripheral blood neutrophil activation patterns are associated with pulmonary inflammatory responses to lipopolysaccharide in humans.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7753-60.
2006: Abraham Edward
Do coagulation abnormalities contribute to sepsis associated organ failure?
Critical care medicine 2006;34(6):1842-4.
2006: Arcaroli John; Silva Eliezer; Maloney James P; He Qianbin; Svetkauskaite Daiva; Murphy James R; Abraham Edward
Variant IRAK-1 haplotype is associated with increased nuclear factor-kappaB activation and worse outcomes in sepsis.
American journal of respiratory and critical care medicine 2006;173(12):1335-41.
2006: Kwak Sang-Hyun; Wang Xue-Qing; He Qianbin; Fang Wen-Feng; Mitra Sanchayita; Bdeir Khalil; Ploplis Victoria A; Xu Zhi; Idell Steven; Cines Douglas; Abraham Edward
Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway.
Thrombosis and haemostasis 2006;95(5):829-35.
2006: Abraham Edward
Progress report on the AJRCCM: continued growth and evolution for the journal.
American journal of respiratory and critical care medicine 2006;173(8):823-4.
2006: Dellinger R Phillip; Abraham Edward; Bernard Gordon; Marshall John C; Vincent Jean-Louis
Controversies in sepsis clinical trials: proceedings of a meeting of the International Sepsis Forum, Lausanne, Switzerland, September 29, 2001.
Journal of critical care 2006;21(1):38-47.
2006: Park Jong Sung; Gamboni-Robertson Fabia; He Qianbin; Svetkauskaite Daiva; Kim Jae-Yeol; Strassheim Derek; Sohn Jang-Won; Yamada Shingo; Maruyama Ikuro; Banerjee Anirban; Ishizaka Akitoshi; Abraham Edward
High mobility group box 1 protein interacts with multiple Toll-like receptors.
American journal of physiology. Cell physiology 2006;290(3):C917-24.
2006: Matthay Michael A; Abraham Edward
Beta-adrenergic agonist therapy as a potential treatment for acute lung injury.
American journal of respiratory and critical care medicine 2006;173(3):254-5.
2006: Vincent Jean-Louis; Abraham Edward
The last 100 years of sepsis.
American journal of respiratory and critical care medicine 2006;173(3):256-63.
2006: Rodriguez Robert M; Abdullah Rabiatu; Miller Robert; Barry Linda; Lungstras-Bufler Kathrin; Bufler Phillip; Dinarello Charles A; Abraham Ed
A pilot study of cytokine levels and white blood cell counts in the diagnosis of necrotizing fasciitis.
The American journal of emergency medicine 2006;24(1):58-61.
2006: Suda K; Kitagawa Y; Ozawa S; Saikawa Y; Ueda M; Abraham E; Kitajima M; Ishizaka A
Serum concentrations of high-mobility group box chromosomal protein 1 before and after exposure to the surgical stress of thoracic esophagectomy: a predictor of clinical course after surgery?
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2006;19(1):5-9.
2005: Abraham Edward
Akt/protein kinase B.
Critical care medicine 2005;33(12 Suppl):S420-2.
2005: Nemery Benoit; Abraham Edward
Environmental health and the AJRCCM.
American journal of respiratory and critical care medicine 2005;172(12):1484-5.
2005: Angus Derek C; Abraham Edward
Intensive insulin therapy in critical illness.
American journal of respiratory and critical care medicine 2005;172(11):1358-9.
2005: Netea Mihai G; Azam Tania; Ferwerda Gerben; Girardin Stephen E; Walsh Mark; Park Jong-Sung; Abraham Edward; Kim Jin-Man; Yoon Do-Young; Dinarello Charles A; Kim Soo-Hyun
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16309-14.
2005: Abraham Edward
Alterations in cell signaling in sepsis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41 Suppl 7():S459-64.
2005: Arcaroli John; Fessler Michael B; Abraham Edward
Genetic polymorphisms and sepsis.
Shock (Augusta, Ga.) 2005;24(4):300-12.
2005: Parikh Chirag R; Abraham Edward; Ancukiewicz Marek; Edelstein Charles L
Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit.
Journal of the American Society of Nephrology : JASN 2005;16(10):3046-52.
2005: Kwak Sang-Hyun; Mitra Sanchayita; Bdeir Khalil; Strassheim Derek; Park Jong Sung; Kim Jael Yeol; Idell Steven; Cines Douglas; Abraham Edward
The kringle domain of urokinase-type plasminogen activator potentiates LPS-induced neutrophil activation through interaction with {alpha}V{beta}3 integrins.
Journal of leukocyte biology 2005;78(4):937-45.
2005: Abraham Edward; Laterre Pierre-François; Garg Rekha; Levy Howard; Talwar Deepak; Trzaskoma Benjamin L; François Bruno; Guy Jeffrey S; Brückmann Martina; Rea-Neto Alvaro; Rossaint Rolf; Perrotin Dominique; Sablotzki Armin; Arkins Nancy; Utterback Barbara G; Macias William L;
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death.
The New England journal of medicine 2005;353(13):1332-41.
2005: O'Brien James M; Ali Naeem A; Abraham Edward
Year in review in Critical Care, 2004: sepsis and multi-organ failure.
Critical care (London, England) 2005;9(4):409-13.
2005: Zeiher Bernhardt G; Steingrub Jay; Laterre Pierre-Francois; Dmitrienko Alex; Fukiishi Yonetaka; Abraham Edward;
LY315920NA/S-5920, a selective inhibitor of group IIA secretory phospholipase A2, fails to improve clinical outcome for patients with severe sepsis.
Critical care medicine 2005;33(8):1741-8.
2005: Marshall John C; Vincent Jean-Louis; Guyatt Gordon; Angus Derek C; Abraham Edward; Bernard Gordon; Bombardier Claire; Calandra Thierry; Jørgensen Henrik Stig; Sylvester Richard; Boers Maarten
Outcome measures for clinical research in sepsis: a report of the 2nd Cambridge Colloquium of the International Sepsis Forum.
Critical care medicine 2005;33(8):1708-16.
2005: Strassheim Derek; Kim Jae-Yeol; Park Jong-Sung; Mitra Sanchayita; Abraham Edward
Involvement of SHIP in TLR2-induced neutrophil activation and acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8064-71.
2005: Fish Douglas N; Teitelbaum Isaac; Abraham Edward
Pharmacokinetics and pharmacodynamics of imipenem during continuous renal replacement therapy in critically ill patients.
Antimicrobial agents and chemotherapy 2005;49(6):2421-8.
2005: van der Poll Tom; Levi Marcel; Nick Jerry A; Abraham Edward
Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans.
American journal of respiratory and critical care medicine 2005;171(10):1125-8.
2005: Kim Jae Yeol; Park Jong Sung; Strassheim Derek; Douglas Ivor; Diaz del Valle Fernando; Asehnoune Karim; Mitra Sanchayita; Kwak Sang Hyun; Yamada Shingo; Maruyama Ikuro; Ishizaka Akitoshi; Abraham Edward
HMGB1 contributes to the development of acute lung injury after hemorrhage.
American journal of physiology. Lung cellular and molecular physiology 2005;288(5):L958-65.
2005: Toy Pearl; Popovsky Mark A; Abraham Edward; Ambruso Daniel R; Holness Leslie G; Kopko Patricia M; McFarland Janice G; Nathens Avery B; Silliman Christopher C; Stroncek David;
Transfusion-related acute lung injury: definition and review.
Critical care medicine 2005;33(4):721-6.
2005: Fabbri Leonardo; Peters Stephen P; Pavord Ian; Wenzel Sally E; Lazarus Stephen C; Macnee William; Lemaire François; Abraham Edward
Allergic rhinitis, asthma, airway biology, and chronic obstructive pulmonary disease in AJRCCM in 2004.
American journal of respiratory and critical care medicine 2005;171(7):686-98.
2005: Bradley T Douglas; Miller York E; Martinez Fernando J; Angus Derek C; Macnee William; Abraham Edward
Interstitial lung disease, lung cancer, lung transplantation, pulmonary vascular disorders, and sleep-disordered breathing in AJRCCM in 2004.
American journal of respiratory and critical care medicine 2005;171(7):675-85.
2005: Abraham Edward; Shapiro Steven D; Leff Alan R
The NIH Public Access Policy and ATS journals.
American journal of respiratory and critical care medicine 2005;171(7):671-2.
2005: Beutz Michelle A; Abraham Edward
Community-acquired pneumonia and sepsis.
Clinics in chest medicine 2005;26(1):19-28.
2005: Levy Mitchell M; Abraham Edward; Zilberberg Marya; MacIntyre Neil R
A descriptive evaluation of transfusion practices in patients receiving mechanical ventilation.
Chest 2005;127(3):928-35.
2005: Nemery Benoit; Yew Wing Wai; Albert Rick; Brun-Buisson Christian; Macnee William; Martinez Fernando J; Angus Derek C; Abraham Edward
Tuberculosis, nontuberculous lung infection, pleural disorders, pulmonary function, respiratory muscles, occupational lung disease, pulmonary infections, and social issues in AJRCCM in 2004.
American journal of respiratory and critical care medicine 2005;171(6):554-62.
2005: Bush Andrew; Accurso Frank; Macnee William; Lazarus Stephen C; Abraham Edward
Cystic fibrosis, pediatrics, control of breathing, pulmonary physiology and anatomy, and surfactant biology in AJRCCM in 2004.
American journal of respiratory and critical care medicine 2005;171(6):545-53.
2005: Angus Derek; Ishizaka Akitoshi; Matthay Michael; Lemaire François; Macnee William; Abraham Edward
Critical care in AJRCCM 2004.
American journal of respiratory and critical care medicine 2005;171(6):537-44.
2005: Asehnoune Karim; Strassheim Derek; Mitra Sanchayita; Yeol Kim Jae; Abraham Edward
Involvement of PKCalpha/beta in TLR4 and TLR2 dependent activation of NF-kappaB.
Cellular signalling 2005;17(3):385-94.
2005: Abraham Edward
Effects of recombinant human activated protein C in human models of endotoxin administration.
Proceedings of the American Thoracic Society 2005;2(3):243-7.
2005: Leff Alan R; Shapiro Steven D; Abraham Edward
The unintended consequences of noble intentions to inform.
Proceedings of the American Thoracic Society 2005;2(1):2-3.
2005: Abraham Edward; Shapiro Steven D; Leff Alan R
The NIH Public Access Policy and ATS journals.
Proceedings of the American Thoracic Society 2005;2(1):1-2.
2004: Nick Jerry A; Coldren Christopher D; Geraci Mark W; Poch Katie R; Fouty Brian W; O'Brien James; Gruber Michael; Zarini Simona; Murphy Robert C; Kuhn Katherine; Richter Don; Kast Kelly R; Abraham Edward
Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis.
Blood 2004;104(13):3878-85.
2004: Moine Pierre; Abraham Edward
Immunomodulation and sepsis: impact of the pathogen.
Shock (Augusta, Ga.) 2004;22(4):297-308.
2004: Barsness Katherine A; Arcaroli John; Harken Alden H; Abraham Edward; Banerjee Anirban; Reznikov Leonid; McIntyre Robert C
Hemorrhage-induced acute lung injury is TLR-4 dependent.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;287(3):R592-9.
2004: Hoyt David B; Holcomb John; Abraham Edward; Atkins Jim; Sopko George;
Working Group on Trauma Research Program summary report: National Heart Lung Blood Institute (NHLBI), National Institute of General Medical Sciences (NIGMS), and National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH), and the Department of Defense (DOD).
The Journal of trauma 2004;57(2):410-5.
2004: Abraham Edward; Andrews Peter; Antonelli Massimo; Brochard Laurent; Brun-Buisson Christian; Dobb Geoffrey; Fagon Jean-Yves; Groeneveld Johan; Mancebo Jordi; Metnitz Philipp; Nava Stefano; Pinsky Michael; Radermacher Peter; Ranieri Marco; Richard Christian; Tasker Robert; Vallet Benoit
Year in review in intensive care medicine-2003. Part 3: intensive care unit organization, scoring, quality of life, ethics, neonatal and pediatrics, and experimental.
Intensive care medicine 2004;30(8):1514-25.
2004: Marshall John C; Foster Debra; Vincent Jean-Louis; Cook Deborah J; Cohen Jonathan; Dellinger R Phillip; Opal Steven; Abraham Edward; Brett Stephen J; Smith Terry; Mehta Sangeeta; Derzko Anastasia; Romaschin Alex;
Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study.
The Journal of infectious diseases 2004;190(3):527-34.
2004: Abraham Edward; Andrews Peter; Antonelli Massimo; Brochard Laurent; Brun-Buisson Christian; Dobb Geoffrey; Fagon Jean-Yves; Groeneveld Johan; Mancebo Jordi; Metnitz Philipp; Nava Stefano; Pinsky Michael; Radermacher Peter; Ranieri Marco; Richard Christian; Tasker Robert; Vallet Benoit
Year in review in intensive care medicine: 2003. II. Brain injury, hemodynamics, gastrointestinal tract, renal failure, metabolism, trauma, and postoperative.
Intensive care medicine 2004;30(7):1266-75.
2004: Abraham Edward; Andrews Peter; Antonelli Massimo; Brochard Laurent; Brun-Buisson Christian; Dobb Geoffrey; Fagon Jean-Yves; Groeneveld Johan; Mancebo Jordi; Metnitz Philipp; Nava Stefano; Pinsky Michael; Radermacher Peter; Ranieri Marco; Richard Christian; Tasker Robert; Vallet Benoît
Year in review in Intensive Care Medicine-2003. Part 1: Respiratory failure, infection and sepsis.
Intensive care medicine 2004;30(6):1017-31.
2004: O'Brien James M; Abraham Edward
Human models of endotoxemia and recombinant human activated protein C.
Critical care medicine 2004;32(5 Suppl):S202-8.
2004: Strassheim Derek; Asehnoune Karim; Park Jong-Sung; Kim Jae-Yeol; He Qianbin; Richter Donald; Kuhn Katherine; Mitra Sanchayita; Abraham Edward
Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5727-33.
2004: Lungstras-Bufler Kathrin; Bufler Philip; Abdullah Rabiatu; Rutherford Christine; Endres Stefan; Abraham Edward; Dinarello Charles A; Rodriguez Robert M
High cytokine levels at admission are associated with fatal outcome in patients with necrotizing fasciitis.
European cytokine network 2004;15(2):135-8.
2004: Strassheim Derek; Asehnoune Karim; Park Jong-Sung; Kim Jae-Yeol; He Qianbin; Richter Donald; Mitra Sanchayita; Arcaroli John; Kuhn Katherine; Abraham Edward
Modulation of bone marrow-derived neutrophil signaling by H2O2: disparate effects on kinases, NF-kappaB, and cytokine expression.
American journal of physiology. Cell physiology 2004;286(3):C683-92.
2004: Asehnoune Karim; Strassheim Derek; Mitra Sanchayita; Kim Jae Yeol; Abraham Edward
Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2522-9.
2004: Opal Steven; Laterre Pierre-Francois; Abraham Edward; Francois Bruno; Wittebole Xavier; Lowry Stephen; Dhainaut Jean-Francois; Warren Brian; Dugernier Thierry; Lopez Angel; Sanchez Miguel; Demeyer Ignace; Jauregui Luis; Lorente Jose Angel; McGee William; Reinhart Konrad; Kljucar Sascha; Souza Sonia; Pribble John;
Recombinant human platelet-activating factor acetylhydrolase for treatment of severe sepsis: results of a phase III, multicenter, randomized, double-blind, placebo-controlled, clinical trial.
Critical care medicine 2004;32(2):332-41.
2004: Park Jong Sung; Svetkauskaite Daiva; He Qianbin; Kim Jae-Yeol; Strassheim Derek; Ishizaka Akitoshi; Abraham Edward
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein.
The Journal of biological chemistry 2004;279(9):7370-7.
2004: Corwin Howard L; Gettinger Andrew; Pearl Ronald G; Fink Mitchell P; Levy Mitchell M; Abraham Edward; MacIntyre Neil R; Shabot M Michael; Duh Mei-Sheng; Shapiro Marc J
The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States.
Critical care medicine 2004;32(1):39-52.
2003: O'Brien James M; Abraham Edward
New approaches to the treatment of sepsis.
Clinics in chest medicine 2003;24(4):521-48, v.
2003: Abraham Edward
Computational design of variant TNF molecules: a novel methodology for inhibition of proinflammatory cascades.
Science's STKE : signal transduction knowledge environment 2003;2003(208):PE51.
2003: Bowler Russell P; Velsor Leonard W; Duda Beth; Chan Edward D; Abraham Edward; Ware Lorraine B; Matthay Michael A; Day Brian J
Pulmonary edema fluid antioxidants are depressed in acute lung injury.
Critical care medicine 2003;31(9):2309-15.
2003: Shapiro Marc J; Gettinger Andrew; Corwin Howard L; Napolitano Lena; Levy Mitchell; Abraham Edward; Fink Mitchell P; MacIntyre Neil; Pearl Ronald G; Shabot M Michael
Anemia and blood transfusion in trauma patients admitted to the intensive care unit.
The Journal of trauma 2003;55(2):269-73; discussion 273-4.
2003: Abraham Edward; Reinhart Konrad; Opal Steven; Demeyer Ignace; Doig Christopher; Rodriguez Angel López; Beale Richard; Svoboda Petr; Laterre Pierre Francois; Simon Stuart; Light Bruce; Spapen Herbert; Stone Judy; Seibert Allan; Peckelsen Claus; De Deyne Cathy; Postier Russell; Pettilä Ville; Artigas Antonio; Percell Sandra R; Shu Vincent; Zwingelstein Christian; Tobias Jeffrey; Poole Lona; Stolzenbach James C; Creasey Abla A;
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2003;290(2):238-47.
2003: Schuster Daniel P; Metzler Michael; Opal Steven; Lowry Stephen; Balk Robert; Abraham Edward; Levy Howard; Slotman Gus; Coyne Eileen; Souza Sonia; Pribble John;
Recombinant platelet-activating factor acetylhydrolase to prevent acute respiratory distress syndrome and mortality in severe sepsis: Phase IIb, multicenter, randomized, placebo-controlled, clinical trial.
Critical care medicine 2003;31(6):1612-9.
2003: Abraham Edward
Nuclear factor-kappaB and its role in sepsis-associated organ failure.
The Journal of infectious diseases 2003;187 Suppl 2():S364-9.
2003: Abraham Edward; Gyetko Margaret R; Kuhn Katherine; Arcaroli John; Strassheim Derek; Park Jong Sung; Shetty Sreerama; Idell Steven
Urokinase-type plasminogen activator potentiates lipopolysaccharide-induced neutrophil activation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5644-51.
2003: Yang Kuang-Yao; Arcaroli John J; Abraham Edward
Early alterations in neutrophil activation are associated with outcome in acute lung injury.
American journal of respiratory and critical care medicine 2003;167(11):1567-74.
2003: Levy Mitchell M; Fink Mitchell P; Marshall John C; Abraham Edward; Angus Derek; Cook Deborah; Cohen Jonathan; Opal Steven M; Vincent Jean-Louis; Ramsay Graham;
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference.
Critical care medicine 2003;31(4):1250-6.
2003: Abraham Edward
Neutrophils and acute lung injury.
Critical care medicine 2003;31(4 Suppl):S195-9.
2003: Levy Mitchell M; Fink Mitchell P; Marshall John C; Abraham Edward; Angus Derek; Cook Deborah; Cohen Jonathan; Opal Steven M; Vincent Jean-Louis; Ramsay Graham;
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference.
Intensive care medicine 2003;29(4):530-8.
2003: Park Jong Sung; Arcaroli John; Yum Ho-Kee; Yang Huan; Wang Haichao; Yang Kuang-Yao; Choe Kang-Hyeon; Strassheim Derek; Pitts Todd M; Tracey Kevin J; Abraham Edward
Activation of gene expression in human neutrophils by high mobility group box 1 protein.
American journal of physiology. Cell physiology 2003;284(4):C870-9.
2003: Bowler Russell P; Arcaroli John; Abraham Edward; Patel Manisha; Chang Ling-Yi; Crapo James D
Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury.
American journal of physiology. Lung cellular and molecular physiology 2003;284(4):L680-7.
2003: Abraham Edward; Naum Chris; Bandi Venkata; Gervich Daniel; Lowry Stephen F; Wunderink Richard; Schein Roland M; Macias William; Skerjanec Simona; Dmitrienko Alex; Farid Nagy; Forgue S Thomas; Jiang Frank
Efficacy and safety of LY315920Na/S-5920, a selective inhibitor of 14-kDa group IIA secretory phospholipase A2, in patients with suspected sepsis and organ failure.
Critical care medicine 2003;31(3):718-28.
2003: Yang Kuang-Yao; Arcaroli John; Kupfner John; Pitts Todd M; Park Jong Sung; Strasshiem Derek; Perng Reury-Perng; Abraham Edward
Involvement of phosphatidylinositol 3-kinase gamma in neutrophil apoptosis.
Cellular signalling 2003;15(2):225-33.
2003: Cox Christopher E; Carson Shannon S; Ely E Wesley; Govert Joseph A; Garrett Joanne M; Brower Roy G; Morris David G; Abraham Edward; Donnabella Vincent; Spevetz Antoinette; Hall Jesse B
Effectiveness of medical resident education in mechanical ventilation.
American journal of respiratory and critical care medicine 2003;167(1):32-8.
2002: Vincent Jean-Louis; Abraham Edward; Annane Djillali; Bernard Gordon; Rivers Emanuel; Van den Berghe Greet
Reducing mortality in sepsis: new directions.
Critical care (London, England) 2002;6 Suppl 3():S1-18.
2002: Strassheim Derek; Park Jong Sung; Abraham Edward
Sepsis: current concepts in intracellular signaling.
The international journal of biochemistry & cell biology 2002;34(12):1527-33.
2002: Dinarello Charles A; Abraham Edward
Does blocking cytokines in sepsis work?
American journal of respiratory and critical care medicine 2002;166(9):1156-7.
2002: Rebuck Jill A; Fish Douglas N; Abraham Edward
Pharmacokinetics of intravenous and oral levofloxacin in critically ill adults in a medical intensive care unit.
Pharmacotherapy 2002;22(10):1216-25.
2002: Arcaroli John; Yang Kuang-Yao; Yum Ho-Kee; Kupfner John; Pitts Todd M; Park Jong Sung; Strassheim Derek; Abraham Edward
Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia.
Journal of leukocyte biology 2002;72(3):571-9.
2002: Abraham Edward
The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
Critical care (London, England) 2002;6(4):277-8.
2002: Abraham Edward; Evans Timothy
Corticosteroids and septic shock.
JAMA : the journal of the American Medical Association 2002;288(7):886-7.
2002: Abraham Edward
Acid suppression in a critical care environment: state of the art and beyond.
Critical care medicine 2002;30(6 Suppl):S349-50.
2002: Arcaroli John; Kupfner John; Yum Ho-Kee; Shenkar Robert; Park Jong Sung; Abraham Edward
Lipopolysaccharide-induced neutrophil gene expression under in vivo or in vitro conditions.
Chest 2002;121(3 Suppl):76S.
2002: Calkins Casey M; Bensard Denis D; Shames Brian D; Pulido Edward J; Abraham Edward; Fernandez Nathan; Meng Xianzhong; Dinarello Charles A; McIntyre Robert C
IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
Journal of endotoxin research 2002;8(1):59-67.
2001: Kupfner J G; Arcaroli J J; Yum H K; Nadler S G; Yang K Y; Abraham E
Role of NF-kappaB in endotoxemia-induced alterations of lung neutrophil apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):7044-51.
2001: Yum H K; Arcaroli J; Kupfner J; Shenkar R; Penninger J M; Sasaki T; Yang K Y; Park J S; Abraham E
Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6601-8.
2001: Abraham E; Reinhart K; Svoboda P; Seibert A; Olthoff D; Dal Nogare A; Postier R; Hempelmann G; Butler T; Martin E; Zwingelstein C; Percell S; Shu V; Leighton A; Creasey A A
Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: a multicenter, randomized, placebo-controlled, single-blind, dose escalation study.
Critical care medicine 2001;29(11):2081-9.
2001: Arcaroli J; Yum H K; Kupfner J; Park J S; Yang K Y; Abraham E
Role of p38 MAP kinase in the development of acute lung injury.
Clinical immunology (Orlando, Fla.) 2001;101(2):211-9.
2001: Malone R S; Fish D N; Abraham E; Teitelbaum I
Pharmacokinetics of cefepime during continuous renal replacement therapy in critically ill patients.
Antimicrobial agents and chemotherapy 2001;45(11):3148-55.
2001: Malone R S; Fish D N; Abraham E; Teitelbaum I
Pharmacokinetics of levofloxacin and ciprofloxacin during continuous renal replacement therapy in critically ill patients.
Antimicrobial agents and chemotherapy 2001;45(10):2949-54.
2001: Song Y; Ao L; Raeburn C D; Calkins C M; Abraham E; Harken A H; Meng X
A low level of TNF-alpha mediates hemorrhage-induced acute lung injury via p55 TNF receptor.
American journal of physiology. Lung cellular and molecular physiology 2001;281(3):L677-84.
2001: Shenkar R; Yum H K; Arcaroli J; Kupfner J; Abraham E
Interactions between CBP, NF-kappaB, and CREB in the lungs after hemorrhage and endotoxemia.
American journal of physiology. Lung cellular and molecular physiology 2001;281(2):L418-26.
2001: Bowler R P; Arcaroli J; Crapo J D; Ross A; Slot J W; Abraham E
Extracellular superoxide dismutase attenuates lung injury after hemorrhage.
American journal of respiratory and critical care medicine 2001;164(2):290-4.
2001: Abraham E; Laterre P F; Garbino J; Pingleton S; Butler T; Dugernier T; Margolis B; Kudsk K; Zimmerli W; Anderson P; Reynaert M; Lew D; Lesslauer W; Passe S; Cooper P; Burdeska A; Modi M; Leighton A; Salgo M; Van der Auwera P;
Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients.
Critical care medicine 2001;29(3):503-10.
2001: Abraham E; Arcaroli J; Shenkar R
Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):522-30.
2001: Arndt P; Abraham E
Immunological therapy of sepsis: experimental therapies.
Intensive care medicine 2001;27 Suppl 1():S104-15.
2000: Abraham E; Carmody A; Shenkar R; Arcaroli J
Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury.
American journal of physiology. Lung cellular and molecular physiology 2000;279(6):L1137-45.
2000: McIntyre R C; Pulido E J; Bensard D D; Shames B D; Abraham E
Thirty years of clinical trials in acute respiratory distress syndrome.
Critical care medicine 2000;28(9):3314-31.
2000: Abraham E
Tissue factor inhibition and clinical trial results of tissue factor pathway inhibitor in sepsis.
Critical care medicine 2000;28(9 Suppl):S31-3.
2000: Abraham E; Arcaroli J; Carmody A; Wang H; Tracey K J
HMG-1 as a mediator of acute lung inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):2950-4.
2000: Arndt P G; Fantuzzi G; Abraham E
Expression of interleukin-18 in the lung after endotoxemia or hemorrhage-induced acute lung injury.
American journal of respiratory cell and molecular biology 2000;22(6):708-13.
2000: Abraham E
NF-kappaB activation.
Critical care medicine 2000;28(4 Suppl):N100-4.
2000: Abraham E
Coagulation abnormalities in acute lung injury and sepsis.
American journal of respiratory cell and molecular biology 2000;22(4):401-4.
2000: Donnahoo K K; Meldrum D R; Shenkar R; Chung C S; Abraham E; Harken A H
Early renal ischemia, with or without reperfusion, activates NFkappaB and increases TNF-alpha bioactivity in the kidney.
The Journal of urology 2000;163(4):1328-32.
2000: Moine P; McIntyre R; Schwartz M D; Kaneko D; Shenkar R; Le Tulzo Y; Moore E E; Abraham E
NF-kappaB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome.
Shock (Augusta, Ga.) 2000;13(2):85-91.
2000: Abraham E
What role does neutrophil apoptosis play in acute respiratory distress syndrome?
Critical care medicine 2000;28(1):253-4.
2000: Abraham E; Matthay M A; Dinarello C A; Vincent J L; Cohen J; Opal S M; Glauser M; Parsons P; Fisher C J; Repine J E
Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation.
Critical care medicine 2000;28(1):232-5.
2000: Abraham E; Papadakos P J; Tharratt R S; Hall J B; Williams G J
Effects of propofol containing EDTA on mineral metabolism in medical ICU patients with pulmonary dysfunction.
Intensive care medicine 2000;26 Suppl 4():S422-32.
1999: Abraham E
Corticosteroids and the neutrophil: cutting both ways.
Critical care medicine 1999;27(11):2583-4.
1999: Pittet D; Harbarth S; Suter P M; Reinhart K; Leighton A; Barker C; Macdonald F; Abraham E
Impact of immunomodulating therapy on morbidity in patients with severe sepsis.
American journal of respiratory and critical care medicine 1999;160(3):852-7.
1999: Abraham E; Baughman R; Fletcher E; Heard S; Lamberti J; Levy H; Nelson L; Rumbak M; Steingrub J; Taylor J; Park Y C; Hynds J M; Freitag J
Liposomal prostaglandin E1 (TLC C-53) in acute respiratory distress syndrome: a controlled, randomized, double-blind, multicenter clinical trial. TLC C-53 ARDS Study Group.
Critical care medicine 1999;27(8):1478-85.
1999: Parsey M V; Kaneko D; Shenkar R; Abraham E
Neutrophil apoptosis in the lung after hemorrhage or endotoxemia: apoptosis and migration are independent of interleukin-1beta.
Chest 1999;116(1 Suppl):67S-68S.
1999: Wang H; Bloom O; Zhang M; Vishnubhakat J M; Ombrellino M; Che J; Frazier A; Yang H; Ivanova S; Borovikova L; Manogue K R; Faist E; Abraham E; Andersson J; Andersson U; Molina P E; Abumrad N N; Sama A; Tracey K J
HMG-1 as a late mediator of endotoxin lethality in mice.
Science (New York, N.Y.) 1999;285(5425):248-51.
1999: Shenkar R; Abraham E
Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):954-62.
1999: Abraham E
Why immunomodulatory therapies have not worked in sepsis.
Intensive care medicine 1999;25(6):556-66.
1999: George C L; Fantuzzi G; Bursten S; Leer L; Abraham E
Effects of lisofylline on hyperoxia-induced lung injury.
The American journal of physiology 1999;276(5 Pt 1):L776-85.
1999: Parsey M V; Kaneko D; Shenkar R; Abraham E
Neutrophil apoptosis in the lung after hemorrhage or endotoxemia: apoptosis and migration are independent of IL-1beta.
Clinical immunology (Orlando, Fla.) 1999;91(2):219-25.
1999: Fish D N; Abraham E
Pharmacokinetics of a clarithromycin suspension administered via nasogastric tube to seriously ill patients.
Antimicrobial agents and chemotherapy 1999;43(5):1277-80.
1999: Tracey K J; Abraham E
From mouse to man: or what have we learned about cytokine-based anti-inflammatory therapies?
Shock (Augusta, Ga.) 1999;11(3):224-5.
1999: Abraham E; Marshall J C
Sepsis and mediator-directed therapy: rethinking the target populations. Mediator-directed therapy in sepsis: rethinking the target populations. Toronto, Canada, 31 October-1 November 1998.
Molecular medicine today 1999;5(2):56-8.
1999: Fuhrman B P; Abraham E; Dellinger R P
Futility of randomized, controlled ARDS trials--a new approach is needed.
Critical care medicine 1999;27(2):431-3.
1999: Abraham E
Toward new definitions of acute respiratory distress syndrome.
Critical care medicine 1999;27(2):237-8.
1999: Abraham E; Kaneko D J; Shenkar R
Effects of endogenous and exogenous catecholamines on LPS-induced neutrophil trafficking and activation.
The American journal of physiology 1999;276(1 Pt 1):L1-8.
1998: Abraham E; Anzueto A; Gutierrez G; Tessler S; San Pedro G; Wunderink R; Dal Nogare A; Nasraway S; Berman S; Cooney R; Levy H; Baughman R; Rumbak M; Light R B; Poole L; Allred R; Constant J; Pennington J; Porter S
Double-blind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock. NORASEPT II Study Group.
Lancet 1998;351(9107):929-33.
1998: Abraham E
Cytokine modifiers: pipe dream or reality?
Chest 1998;113(3 Suppl):224S-227S.
1998: Parsey M V; Tuder R M; Abraham E
Neutrophils are major contributors to intraparenchymal lung IL-1 beta expression after hemorrhage and endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):1007-13.
1997: Meldrum D R; Shenkar R; Sheridan B C; Cain B S; Abraham E; Harken A H
Hemorrhage activates myocardial NFkappaB and increases TNF-alpha in the heart.
Journal of molecular and cellular cardiology 1997;29(10):2849-54.
1997: Moine P; Shenkar R; Kaneko D; Le Tulzo Y; Abraham E
Systemic blood loss affects NF-kappa B regulatory mechanisms in the lungs.
The American journal of physiology 1997;273(1 Pt 1):L185-92.
1997: Opal S M; Fisher C J; Dhainaut J F; Vincent J L; Brase R; Lowry S F; Sadoff J C; Slotman G J; Levy H; Balk R A; Shelly M P; Pribble J P; LaBrecque J F; Lookabaugh J; Donovan H; Dubin H; Baughman R; Norman J; DeMaria E; Matzel K; Abraham E; Seneff M
Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group.
Critical care medicine 1997;25(7):1115-24.
1997: Abraham E; Glauser M P; Butler T; Garbino J; Gelmont D; Laterre P F; Kudsk K; Bruining H A; Otto C; Tobin E; Zwingelstein C; Lesslauer W; Leighton A
p55 Tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock. A randomized controlled multicenter trial. Ro 45-2081 Study Group.
JAMA : the journal of the American Medical Association 1997;277(19):1531-8.
1997: Le Tulzo Y; Shenkar R; Kaneko D; Moine P; Fantuzzi G; Dinarello C A; Abraham E
Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression.
The Journal of clinical investigation 1997;99(7):1516-24.
1997: Abraham E
Therapies for sepsis. Emerging therapies for sepsis and septic shock.
The Western journal of medicine 1997;166(3):195-200.
1997: Abraham E
NF-kappa B and reactive oxygen intermediates.
Shock (Augusta, Ga.) 1997;7(2):97.
1997: Shenkar R; Abraham E
Hemorrhage induces rapid in vivo activation of CREB and NF-kappaB in murine intraparenchymal lung mononuclear cells.
American journal of respiratory cell and molecular biology 1997;16(2):145-52.
1996: Shea L M; Beehler C; Schwartz M; Shenkar R; Tuder R; Abraham E
Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):3902-8.
1996: Schwartz M D; Moore E E; Moore F A; Shenkar R; Moine P; Haenel J B; Abraham E
Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome.
Critical care medicine 1996;24(8):1285-92.
1996: Bursten S L; Federighi D A; Parsons P; Harris W E; Abraham E; Moore E E; Moore F A; Bianco J A; Singer J W; Repine J E
An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome.
Critical care medicine 1996;24(7):1129-36.
1996: Fisher C J; Agosti J M; Opal S M; Lowry S F; Balk R A; Sadoff J C; Abraham E; Schein R M; Benjamin E
Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group.
The New England journal of medicine 1996;334(26):1697-702.
1996: Shenkar R; Schwartz M D; Terada L S; Repine J E; McCord J; Abraham E
Hemorrhage activates NF-kappa B in murine lung mononuclear cells in vivo.
The American journal of physiology 1996;270(5 Pt 1):L729-35.
1996: Abraham E; Gallagher T J; Fink S
Clinical evaluation of a multiparameter intra-arterial blood-gas sensor.
Intensive care medicine 1996;22(5):507-13.
1996: Abraham E
Alterations in transcriptional regulation of proinflammatory and immunoregulatory cytokine expression by hemorrhage, injury, and critical illness.
New horizons (Baltimore, Md.) 1996;4(2):184-93.
1996: Shenkar R; Abraham E
Plasma from hemorrhaged mice activates CREB and increases cytokine expression in lung mononuclear cells through a xanthine oxidase-dependent mechanism.
American journal of respiratory cell and molecular biology 1996;14(2):198-206.
1996: Abraham E; Park Y C; Covington P; Conrad S A; Schwartz M
Liposomal prostaglandin E1 in acute respiratory distress syndrome: a placebo-controlled, randomized, double-blind, multicenter clinical trial.
Critical care medicine 1996;24(1):10-5.
1995: Abraham E; Jesmok G; Tuder R; Allbee J; Chang Y H
Contribution of tumor necrosis factor-alpha to pulmonary cytokine expression and lung injury after hemorrhage and resuscitation.
Critical care medicine 1995;23(8):1319-26.
1995: Schwartz M D; Repine J E; Abraham E
Xanthine oxidase-derived oxygen radicals increase lung cytokine expression in mice subjected to hemorrhagic shock.
American journal of respiratory cell and molecular biology 1995;12(4):434-40.
1995: Abraham E; Wunderink R; Silverman H; Perl T M; Nasraway S; Levy H; Bone R; Wenzel R P; Balk R; Allred R
Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group.
JAMA : the journal of the American Medical Association 1995;273(12):934-41.
1995: Abraham E; Bursten S; Shenkar R; Allbee J; Tuder R; Woodson P; Guidot D M; Rice G; Singer J W; Repine J E
Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice.
The Journal of experimental medicine 1995;181(2):569-75.
1995: Shenkar R; Abraham E
Effects of treatment with the 21-aminosteroid, U7438F, on pulmonary cytokine expression following hemorrhage and resuscitation.
Critical care medicine 1995;23(1):132-9.
1995: Shenkar R; Cohen A J; Vestweber D; Miller Y E; Tuder R; Abraham E
Hemorrhage and resuscitation alter the expression of ICAM-1 and P-selectin in mice.
Journal of inflammation 1995;45(4):248-59.
1994: Abraham E; Allbee J
Effects of therapy with interleukin-1 receptor antagonist on pulmonary cytokine expression following hemorrhage and resuscitation.
Lymphokine and cytokine research 1994;13(6):343-7.
1994: Abraham E; Coulson W F; Schwartz M D; Allbee J
Effects of therapy with soluble tumour necrosis factor receptor fusion protein on pulmonary cytokine expression and lung injury following haemorrhage and resuscitation.
Clinical and experimental immunology 1994;98(1):29-34.
1994: Shenkar R; Coulson W F; Abraham E
Anti-transforming growth factor-beta monoclonal antibodies prevent lung injury in hemorrhaged mice.
American journal of respiratory cell and molecular biology 1994;11(3):351-7.
1994: Law M M; Cryer H G; Abraham E
Elevated levels of soluble ICAM-1 correlate with the development of multiple organ failure in severely injured trauma patients.
The Journal of trauma 1994;37(1):100-9; discussion 109-10.
1994: Abraham E; Raffin T A
Sepsis therapy trials. Continued disappointment or reason for hope?
JAMA : the journal of the American Medical Association 1994;271(23):1876-8.
1994: Meade P; Shoemaker W C; Donnelly T J; Abraham E; Jagels M A; Cryer H G; Hugli T E; Bishop M H; Wo C C
Temporal patterns of hemodynamics, oxygen transport, cytokine activity, and complement activity in the development of adult respiratory distress syndrome after severe injury.
The Journal of trauma 1994;36(5):651-7.
1994: Donnelly T J; Meade P; Jagels M; Cryer H G; Law M M; Hugli T E; Shoemaker W C; Abraham E
Cytokine, complement, and endotoxin profiles associated with the development of the adult respiratory distress syndrome after severe injury.
Critical care medicine 1994;22(5):768-76.
1994: Abraham E
Clinical sepsis trials.
Chest 1994;105(3 Suppl):53S-55S.
1994: Shenkar R; Coulson W F; Abraham E
Hemorrhage and resuscitation induce alterations in cytokine expression and the development of acute lung injury.
American journal of respiratory cell and molecular biology 1994;10(3):290-7.
1994: Shenkar R; Chang Y H; Abraham E
Cytokine expression in Peyer's patches following hemorrhage and resuscitation.
Shock (Augusta, Ga.) 1994;1(1):25-30.
1993: Shoemaker W C; Appel P L; Kram H B; Bishop M H; Abraham E
Sequence of physiologic patterns in surgical septic shock.
Critical care medicine 1993;21(12):1876-89.
1993: Shoemaker W C; Appel P L; Kram H B; Bishop M H; Abraham E
Temporal hemodynamic and oxygen transport patterns in medical patients. Septic shock.
Chest 1993;104(5):1529-36.
1993: Shenkar R; Abraham E
Effects of hemorrhage on cytokine gene transcription.
Lymphokine and cytokine research 1993;12(4):237-47.
1993: Hoch R C; Rodriguez R; Manning T; Bishop M; Mead P; Shoemaker W C; Abraham E
Effects of accidental trauma on cytokine and endotoxin production.
Critical care medicine 1993;21(6):839-45.
1993: Abraham E
T- and B-cell function and their roles in resistance to infection.
New horizons (Baltimore, Md.) 1993;1(1):28-36.
1993: Shoemaker W C; Appel P L; Kram H B; Bishop M; Abraham E
Hemodynamic and oxygen transport monitoring to titrate therapy in septic shock.
New horizons (Baltimore, Md.) 1993;1(1):145-59.
1992: Abraham E; Shah S
Intranasal immunization with liposomes containing IL-2 enhances bacterial polysaccharide antigen-specific pulmonary secretory antibody response.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(11):3719-26.
1992: Abraham E; Chang Y H
Haemorrhage-induced alterations in function and cytokine production of T cells and T cell subpopulations.
Clinical and experimental immunology 1992;90(3):497-502.
1992: Abraham E; Chang Y H
Modulation of the posthemorrhage bacterial polysaccharide antigen-specific antibody response by interleukins 2 and 4.
Lymphokine and cytokine research 1992;11(4):241-6.
1992: Abraham E; Stevens P
Effects of granulocyte colony-stimulating factor in modifying mortality from Pseudomonas aeruginosa pneumonia after hemorrhage.
Critical care medicine 1992;20(8):1127-33.
1992: Robinson A; Abraham E
Effects of haemorrhage on bacterial antigen specific pulmonary plasma cell function.
Clinical and experimental immunology 1992;88(1):124-8.
1992: Abraham E
Intranasal immunization with bacterial polysaccharide containing liposomes enhances antigen-specific pulmonary secretory antibody response.
Vaccine 1992;10(7):461-8.
1991: Robinson A; Abraham E
Effects of hemorrhage and resuscitation on bacterial antigen-specific pulmonary plasma cell function.
Critical care medicine 1991;19(10):1285-93.
1991: Abraham E; Robinson A
Oral immunization with bacterial polysaccharide and adjuvant enhances antigen-specific pulmonary secretory antibody response and resistance to pneumonia.
Vaccine 1991;9(10):757-64.
1991: Abraham E
Physiologic stress and cellular ischemia: relationship to immunosuppression and susceptibility to sepsis.
Critical care medicine 1991;19(5):613-8.
1991: Abraham E
Effects of stress on cytokine production.
Methods and achievements in experimental pathology 1991;14():45-62.
1990: Robinson A; Abraham E
Hemorrhage in mice produces alterations in pulmonary B cell repertoires.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(11):3734-9.
1990: Abraham E; Chang Y H
Effects of intravenous immunoglobulin on hemorrhage-induced alterations in plasma cell repertoires.
Critical care medicine 1990;18(11):1252-6.
1990: Abraham E; Freitas A A; Jagels M; Chang Y H
Transfer of T or CD8+ cells from hemorrhaged mice produce alterations in bacterial antigen specific plasma cell repertoires in normal syngeneic recipients.
Immunobiology 1990;181(4-5):379-87.
1990: Abraham E; Andrade L; Freitas A A
Immunoglobulin VH gene expression following hemorrhage.
Molecular immunology 1990;27(9):921-7.
1990: Abraham E; Chang Y H
Hemorrhage in mice produces alterations in intestinal B cell repertoires.
Cellular immunology 1990;128(1):165-74.
1990: Chang Y H; Jagels M; Abraham E
Haemorrhage produces depressions in alloantigen-specific immune responses in the mouse through activation of suppressor T cells.
Clinical and experimental immunology 1990;80(3):478-83.
1990: Abraham E; Freitas A A; Coutinho A A
Purification and characterization of intraparenchymal lung lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(6):2117-22.
1989: Abraham E; Freitas A A
Hemorrhage in mice induces alterations in immunoglobulin-secreting B cells.
Critical care medicine 1989;17(10):1015-9.
1989: Abraham E
Host defense abnormalities after hemorrhage, trauma, and burns.
Critical care medicine 1989;17(9):934-9.
1989: Abraham E; Freitas A A; Coutinho A A
Hemorrhage in mice produces alterations in B cell repertoires.
Cellular immunology 1989;122(1):208-17.
1989: Abraham E
Tumor necrosis factor.
Critical care medicine 1989;17(6):590-1.
1989: Abraham E; Freitas A A
Hemorrhage produces abnormalities in lymphocyte function and lymphokine generation.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(3):899-906.
1988: Abraham E; Fink S
Conjunctival oxygen tension monitoring in emergency department patients.
The American journal of emergency medicine 1988;6(6):549-54.
1988: Skootsky S A; Abraham E
Continuous oxygen consumption measurement during initial emergency department resuscitation of critically ill patients.
Critical care medicine 1988;16(7):706-9.
1988: Abraham E; Richmond N J; Chang Y H
Effects of hemorrhage on interleukin-1 production.
Circulatory shock 1988;25(1):33-40.
1988: Abraham E; Chang Y H
Generation of functionally active suppressor cells by haemorrhage and haemorrhagic serum.
Clinical and experimental immunology 1988;72(2):238-42.
1988: Abraham E; Tanaka T; Chang Y H
Effects of hemorrhagic serum on interleukin-2 generation and utilization.
Critical care medicine 1988;16(4):307-11.
1988: Fink S; Abraham E; Ehrlich H
Postoperative monitoring of conjunctival oxygen tension and temperature.
International journal of clinical monitoring and computing 1988;5(1):37-43.
1987: Okrent D G; Abraham E; Winston D
Cardiorespiratory patterns in viral septicemia.
The American journal of medicine 1987;83(4):681-6.
1987: Abraham E
Conjunctival oxygen tension monitoring.
International anesthesiology clinics 1987;25(3):97-112.
1986: Abraham E; Fink S
Cardiorespiratory and conjunctival oxygen tension monitoring during resuscitation from hemorrhage.
Critical care medicine 1986;14(12):1004-9.
1986: Abraham E; Regan R F; Chang Y H
Lack of effect of exogenous recombinant interleukin-2 on trauma-induced abnormalities in lymphocyte proliferation.
Critical care medicine 1986;14(10):847-51.
1986: Abraham E; Lee G; Morgan M T
Conjunctival oxygen tension monitoring during helicopter transport of critically ill patients.
Annals of emergency medicine 1986;15(7):782-6.
1986: Smith M; Abraham E
Conjunctival oxygen tension monitoring during hemorrhage.
The Journal of trauma 1986;26(3):217-24.
1986: Abraham E; Chang Y H
Cellular and humoral bases of hemorrhage-induced depression of lymphocyte function.
Critical care medicine 1986;14(2):81-6.
1986: Abraham E; Markle D R; Pinholster G; Fink S E
Noninvasive measurement of conjunctival PCO2 with a fiberoptic sensor.
Critical care medicine 1986;14(2):138-41.
1986: Abraham E; Lee R J; Chang Y H
The role of interleukin 2 in hemorrhage-induced abnormalities of lymphocyte proliferation.
Circulatory shock 1986;18(3):205-13.
1985: Abraham E; Regan R F
The effects of hemorrhage and trauma on interleukin 2 production.
Archives of surgery (Chicago, Ill. : 1960) 1985;120(12):1341-4.
1985: Abraham E; Fink S E; Markle D R; Pinholster G; Tsang M
Continuous monitoring of tissue pH with a fiberoptic conjunctival sensor.
Annals of emergency medicine 1985;14(9):840-4.
1985: Abraham E; Shoemaker W C; McCartney S F
Cardiorespiratory patterns in severe delirium tremens.
Archives of internal medicine 1985;145(6):1057-9.
1985: Bland R D; Shoemaker W C; Abraham E; Cobo J C
Hemodynamic and oxygen transport patterns in surviving and nonsurviving postoperative patients.
Critical care medicine 1985;13(2):85-90.
1985: Abraham E; Chang Y H
The effects of hemorrhage on mitogen-induced lymphocyte proliferation.
Circulatory shock 1985;15(2):141-9.
1984: Abraham E; Oye R K; Smith M
Detection of blood volume deficits through conjunctival oxygen tension monitoring.
Critical care medicine 1984;12(11):931-4.
1984: Abraham E; Smith M; Silver L
Continuous monitoring of critically ill patients with transcutaneous oxygen and carbon dioxide and conjunctival oxygen sensors.
Annals of emergency medicine 1984;13(11):1021-6.
1984: Abraham E; Chang Y H
Effects of hemorrhage on inflammatory response.
Archives of surgery (Chicago, Ill. : 1960) 1984;119(10):1154-7.
1984: Abraham E; Cobo J C; Bland R D; Shoemaker W C
Cardiorespiratory effects of pneumatic trousers in critically ill patients.
Archives of surgery (Chicago, Ill. : 1960) 1984;119(8):912-6.
1984: Abraham E; Shoemaker W C; Cheng P H
Cardiorespiratory responses to fluid administration in peritonitis.
Critical care medicine 1984;12(8):664-8.
1984: Abraham E; Smith M; Silver L
Conjunctival and transcutaneous oxygen monitoring during cardiac arrest and cardiopulmonary resuscitation.
Critical care medicine 1984;12(5):419-21.
1984: Abraham E; Ehrlich H
Conjunctival and transcutaneous oxygen monitoring during resuscitation.
Annals of emergency medicine 1984;13(4):287-9.
1984: Cobo J C; Abraham E; Bland R D; Shoemaker W C
Sequential hemodynamic and oxygen transport abnormalities in patients with acute pancreatitis.
Surgery 1984;95(3):324-30.
1984: Abraham E; Bland R D; Cobo J C; Shoemaker W C
Sequential cardiorespiratory patterns associated with outcome in septic shock.
Chest 1984;85(1):75-80.
1983: Abraham E; Shoemaker W C; Bland R D; Cobo J C
Sequential cardiorespiratory patterns in septic shock.
Critical care medicine 1983;11(10):799-803.
1983: Abraham E; Gong H
Pneumatic antishock trousers and their role in critical care medicine.
Respiratory care 1983;28(8):1022-7.
1983: Abraham E; Shapiro M; Podolsky S
Central venous catheterization in the emergency setting.
Critical care medicine 1983;11(7):515-7.
1983: Brenner B E; Abraham E; Simon R R
Position and diaphoresis in acute asthma.
The American journal of medicine 1983;74(6):1005-9.
1983: Abraham E; Brenner B E; Simon R R
Cystitis and pyelonephritis.
Annals of emergency medicine 1983;12(4):228-34.
1982: Abraham E; Gong H; Tashkin D P; Baraff L J; Geehr E
Effect of pneumatic trousers on pulmonary function.
Critical care medicine 1982;10(11):754-7.
1982: Simon R R; Bailey T D; Abraham E; Brenner B
A new technique for securing a chest tube.
Annals of emergency medicine 1982;11(11):619-21.

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