Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Matthew Farrer
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Disorders
Physiology
Procedures
Chemicals & Drugs
Concepts & Ideas
Genes & Molecular Sequences
Anatomy
Sign-in to see full Profile
Network (preview)
61
Wszolek, Zbigniew
57
Hardy, John
49
Ross, Owen
42
Hulihan, Mary
41
Lincoln, Sarah
36
Kachergus, Jennifer
34
Uitti, Ryan
29
dickson, dennis
29
Maraganore, Demetrius
29
Aasly, Jan
23
Lynch, Timothy
22
Gwinn-Hardy, Katrina
22
Toft, Mathias
20
Lincoln, Sarah
19
Mata, Ignacio
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Matthew Farrer (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Puschmann Andreas; Ross Owen A; Vilariño-Güell Carles; Lincoln Sarah J; Kachergus Jennifer M; Cobb Stephanie A; Lindquist Suzanne G; Nielsen Jørgen E; Wszolek Zbigniew K; Farrer Matthew; Widner Håkan; van Westen Danielle; Hägerström Douglas; Markopoulou Katerina; Chase Bruce A; Nilsson Karin; Reimer Jan; Nilsson Christer
A Swedish family with de novo alpha-synuclein A53T mutation: evidence for early cortical dysfunction.
Parkinsonism & related disorders 2009;15(9):627-32.
-
2009: Krygowska-Wajs Anna; Cheshire William P; Wszolek Zbigniew K; Hubalewska-Dydejczyk Alicja; Jasinska-Myga Barbara; Farrer Matthew J; Moskala Marek; Sowa-Staszczak Anna
Evaluation of gastric emptying in familial and sporadic Parkinson disease.
Parkinsonism & related disorders 2009;15(9):692-6.
-
2009: Cobb Stephanie A; Wider Christian; Ross Owen A; Mata Ignacio F; Adler Charles H; Rajput Alex; Rajput Ali H; Wu Ruey-Meei; Hauser Robert; Josephs Keith A; Carr Jonathan; Gwinn Katrina; Heckman Michael G; Aasly Jan O; Lynch Timothy; Uitti Ryan J; Wszolek Zbigniew K; Kapatos Gregory; Farrer Matthew J
GCH1 in early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(14):2070-5.
-
2009: Wider Christian; Lincoln Sarah; Dachsel Justus C; Kapatos Gregory; Heckman Michael G; Diehl Nancy N; Papapetropoulos Spiridon; Mash Deborah; Rajput Alex; Rajput Ali H; Dickson Dennis W; Wszolek Zbigniew K; Farrer Matthew J
GCH1 expression in human cerebellum from healthy individuals is not gender dependent.
Neuroscience letters 2009;462(1):73-5.
-
2009: Nishioka Kenya; Ross Owen A; Ishii Kenji; Kachergus Jennifer M; Ishiwata Kiichi; Kitagawa Mayumi; Kono Satoshi; Obi Tomokazu; Mizoguchi Koichi; Inoue Yuichi; Imai Hisamasa; Takanashi Masashi; Mizuno Yoshikuni; Farrer Matthew J; Hattori Nobutaka
Expanding the clinical phenotype of SNCA duplication carriers.
Movement disorders : official journal of the Movement Disorder Society 2009;24(12):1811-9.
-
2009: Keeling Brett H; Vilariño-Güell Carles; Ross Owen A; Wszolek Zbigniew K; Uitti Ryan J; Farrer Matthew J
DRD3 Ser9Gly and HS1BP3 Ala265Gly are not associated with Parkinson disease.
Neuroscience letters 2009;461(2):74-5.
-
2009: Jasinska-Myga B; Wider C; Opala G; Krygowska-Wajs A; Barcikowska M; Czyzewski K; Baker M; Rademakers R; Uitti R J; Farrer M J; Ross O A; Wszolek Z K
GRN 3'UTR+78 C>T is not associated with risk for Parkinson's disease.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2009;16(8):909-11.
-
2009: Golub Yulia; Berg Daniela; Calne Donald B; Pfeiffer Ronald F; Uitti Ryan J; Stoessl A Jon; Wszolek Zbigniew K; Farrer Matthew J; Mueller Jakob C; Gasser Thomas; Fuchs Julia
Genetic factors influencing age at onset in LRRK2-linked Parkinson disease.
Parkinsonism & related disorders 2009;15(7):539-41.
-
2009: Vilariño-Güell C; Chai H; Keeling B H; Young J E; Rajput A; Lynch T; Aasly J O; Uitti R J; Wszolek Z K; Farrer M J; Lin S-C
MEIS1 p.R272H in familial restless legs syndrome.
Neurology 2009;73(3):243-5.
-
2009: Taylor Juliet M; Wu Ruey-Meei; Farrer Matthew J; Delatycki Martin B; Lockhart Paul J
Analysis of PArkin Co-Regulated Gene in a Taiwanese-ethnic Chinese cohort with early-onset Parkinson's disease.
Parkinsonism & related disorders 2009;15(6):417-21.
-
2009: Ross Owen A; Spanaki Cleanthe; Griffith Alida; Lin Chin-Hsien; Kachergus Jennifer; Haugarvoll Kristoffer; Latsoudis Helen; Plaitakis Andreas; Ferreira Joaquim J; Sampaio Cristina; Bonifati Vincenzo; Wu Ruey-Meei; Zabetian Cyrus P; Farrer Matthew J
Haplotype analysis of Lrrk2 R1441H carriers with parkinsonism.
Parkinsonism & related disorders 2009;15(6):466-7.
-
2009: Farrer Matthew J; Williams Lindsey N; Algom Avi A; Kachergus Jennifer; Hulihan Mary M; Ross Owen A; Rajput Alex; Papapetropoulos Spiridon; Mash Deborah C; Dickson Dennis W
Glucosidase-beta variations and Lewy body disorders.
Parkinsonism & related disorders 2009;15(6):414-6.
-
2009: Ritz Beate R; Manthripragada Angelika D; Costello Sadie; Lincoln Sarah J; Farrer Matthew J; Cockburn Myles; Bronstein Jeff
Dopamine transporter genetic variants and pesticides in Parkinson's disease.
Environmental health perspectives 2009;117(6):964-9.
-
2009: Vilariño-Güell C; Wider C; Soto-Ortolaza A I; Cobb S A; Kachergus J M; Keeling B H; Dachsel J C; Hulihan M M; Dickson D W; Wszolek Z K; Uitti R J; Graff-Radford N R; Boeve B F; Josephs K A; Miller B; Boylan K B; Gwinn K; Adler C H; Aasly J O; Hentati F; Destée A; Krygowska-Wajs A; Chartier-Harlin M-C; Ross O A; Rademakers R; Farrer M J
Characterization of DCTN1 genetic variability in neurodegeneration.
Neurology 2009;72(23):2024-8.
-
2009: Puschmann Andreas; Wszolek Zbigniew K; Farrer Matthew; Gustafson Lars; Widner Håkan; Nilsson Christer
Alpha-synuclein multiplications with parkinsonism, dementia or progressive myoclonus?
Parkinsonism & related disorders 2009;15(5):390-2.
-
2009: Wider Christian; Dickson Dennis W; Stoessl A Jon; Tsuboi Yoshio; Chapon Françoise; Gutmann Ludwig; Lechevalier Bernard; Calne Donald B; Personett David A; Hulihan Mary; Kachergus Jennifer; Rademakers Rosa; Baker Matthew C; Grantier Linda L; Sujith O K; Brown Laura; Calne Susan; Farrer Matthew J; Wszolek Zbigniew K
Pallidonigral TDP-43 pathology in Perry syndrome.
Parkinsonism & related disorders 2009;15(4):281-6.
-
2009: Wider Christian; Lincoln Sarah J; Heckman Michael G; Diehl Nancy N; Stone Jeremy T; Haugarvoll Kristoffer; Aasly Jan O; Gibson J Mark; Lynch Timothy; Rajput Alex; Rajput Michele L; Uitti Ryan J; Wszolek Zbigniew K; Farrer Matthew J; Ross Owen A
Phactr2 and Parkinson's disease.
Neuroscience letters 2009;453(1):9-11.
-
2009: Vilariño-Güell Carles; Ross Owen A; Soto Alexandra I; Farrer Matthew J; Haugarvoll Kristoffer; Aasly Jan O; Uitti Ryan J; Wszolek Zbigniew K
Reported mutations in GIGYF2 are not a common cause of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2009;24(4):619-20.
-
2009: Vilariño-Güell Carles; Soto Alexandra I; Lincoln Sarah J; Ben Yahmed Samia; Kefi Mounir; Heckman Michael G; Hulihan Mary M; Chai Hua; Diehl Nancy N; Amouri Rim; Rajput Alex; Mash Deborah C; Dickson Dennis W; Middleton Lefkos T; Gibson Rachel A; Hentati Faycal; Farrer Matthew J
ATP13A2 variability in Parkinson disease.
Human mutation 2009;30(3):406-10.
-
2009: Haugarvoll Kristoffer; Toft Mathias; Skipper Lisa; Heckman Michael G; Crook Julia E; Soto Alexandra; Ross Owen A; Hulihan Mary M; Kachergus Jennifer M; Sando Sigrid B; White Linda R; Lynch Timothy; Gibson J Mark; Uitti Ryan J; Wszolek Zbigniew K; Aasly Jan O; Farrer Matthew J
Fine-mapping and candidate gene investigation within the PARK10 locus.
European journal of human genetics : EJHG 2009;17(3):336-43.
-
2009: Young Jessica E; Vilariño-Güell Carles; Lin Siong-Chi; Wszolek Zbigniew K; Farrer Matthew J
Clinical and genetic description of a family with a high prevalence of autosomal dominant restless legs syndrome.
Mayo Clinic proceedings. Mayo Clinic 2009;84(2):134-8.
-
2009: Farrer Matthew J; Hulihan Mary M; Kachergus Jennifer M; Dächsel Justus C; Stoessl A Jon; Grantier Linda L; Calne Susan; Calne Donald B; Lechevalier Bernard; Chapon Francoise; Tsuboi Yoshio; Yamada Tatsuo; Gutmann Ludwig; Elibol Bülent; Bhatia Kailash P; Wider Christian; Vilariño-Güell Carles; Ross Owen A; Brown Laura A; Castanedes-Casey Monica; Dickson Dennis W; Wszolek Zbigniew K
DCTN1 mutations in Perry syndrome.
Nature genetics 2009;41(2):163-5.
-
2009: Wider Christian; Dachsel Justus C; Soto Alexandra I; Heckman Michael G; Diehl Nancy N; Yue Mei; Lincoln Sarah; Aasly Jan O; Haugarvoll Kristoffer; Trojanowski John Q; Papapetropoulos Spiridon; Mash Deborah; Rajput Alex; Rajput Ali H; Gibson J Mark; Lynch Timothy; Dickson Dennis W; Uitti Ryan J; Wszolek Zbigniew K; Farrer Matthew J; Ross Owen A
FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression.
Movement disorders : official journal of the Movement Disorder Society 2009;24(3):455-9.
-
2009: Lee Ming-Jen; Mata Ignacio F; Lin Chin-Hsien; Tzen Kai-Yuan; Lincoln Sarah J; Bounds Rebecca; Lockhart Paul J; Hulihan Mary M; Farrer Matthew J; Wu Ruey-Meei
Genotype-phenotype correlates in Taiwanese patients with early-onset recessive Parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2009;24(1):104-8.
-
2008: Nandhagopal R; Mak E; Schulzer M; McKenzie J; McCormick S; Sossi V; Ruth T J; Strongosky A; Farrer M J; Wszolek Z K; Stoessl A J
Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study.
Neurology 2008;71(22):1790-5.
-
2008: Strongosky Audrey J; Farrer Matthew; Wszolek Zbigniew K
Are Parkinson disease patients protected from some but not all cancers?
Neurology 2008;71(20):1650; author reply 1650-1.
-
2008: Ross Owen A; Soto Alexandra I; Vilariño-Güell Carles; Heckman Michael G; Diehl Nancy N; Hulihan Mary M; Aasly Jan O; Sando Sigrid; Gibson J Mark; Lynch Timothy; Krygowska-Wajs Anna; Opala Grzegorz; Barcikowska Maria; Czyzewski Krzysztof; Uitti Ryan J; Wszolek Zbigniew K; Farrer Matthew J
Genetic variation of Omi/HtrA2 and Parkinson's disease.
Parkinsonism & related disorders 2008;14(7):539-43.
-
2008: Ross Owen A; Heckman Michael G; Soto Alexandra I; Diehl Nancy N; Haugarvoll Kristoffer; Vilariño-Güell Carles; Aasly Jan O; Sando Sigrid; Gibson J Mark; Lynch Timothy; Krygowska-Wajs Anna; Opala Grzegorz; Barcikowska Maria; Czyzewski Krzysztof; Uitti Ryan J; Wszolek Zbigniew K; Farrer Matthew J
Dopamine beta-hydroxylase -1021C>T association and Parkinson's disease.
Parkinsonism & related disorders 2008;14(7):544-7.
-
2008: Myhre R; Toft M; Kachergus J; Hulihan M M; Aasly J O; Klungland H; Farrer M J
Multiple alpha-synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population.
Acta neurologica Scandinavica 2008;118(5):320-7.
-
2008: Ishihara-Paul L; Hulihan M M; Kachergus J; Upmanyu R; Warren L; Amouri R; Elango R; Prinjha R K; Soto A; Kefi M; Zouari M; Sassi S B; Yahmed S B; El Euch-Fayeche G; Matthews P M; Middleton L T; Gibson R A; Hentati F; Farrer M J
PINK1 mutations and parkinsonism.
Neurology 2008;71(12):896-902.
-
2008: Djaldetti R; Hassin-Baer S; Farrer M J; Vilariño-Güell C; Ross O A; Kolianov V; Yust-Katz S; Treves T A; Barhum Y; Hulihan M; Melamed E
Clinical characteristics of Parkinson's disease among Jewish Ethnic groups in Israel.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(9):1279-84.
-
2008: Lin Chin-Hsien; Tzen Kai-Yuan; Yu Chin-Yi; Tai Chun-Hwei; Farrer Matthew J; Wu Ruey-Meei
LRRK2 mutation in familial Parkinson's disease in a Taiwanese population: clinical, PET, and functional studies.
Journal of biomedical science 2008;15(5):661-7.
-
2008: Wider C; Skipper L; Solida A; Brown L; Farrer M; Dickson D; Wszolek Z K; Vingerhoets F J G
Autosomal dominant dopa-responsive parkinsonism in a multigenerational Swiss family.
Parkinsonism & related disorders 2008;14(6):465-70.
-
2008: Vilariño-Güell C; Soto A I; Young J E; Lin S-C; Uitti R J; Wszolek Z K; Farrer M J
Susceptibility genes for restless legs syndrome are not associated with Parkinson disease.
Neurology 2008;71(3):222-3.
-
2008: Hulihan Mary M; Ishihara-Paul Lianna; Kachergus Jennifer; Warren Liling; Amouri Rim; Elango Ramu; Prinjha Rab K; Upmanyu Ruchi; Kefi Mounir; Zouari Mourad; Sassi Samia Ben; Yahmed Samia Ben; El Euch-Fayeche Ghada; Matthews Paul M; Middleton Lefkos T; Gibson Rachel A; Hentati Fayçal; Farrer Matthew J
LRRK2 Gly2019Ser penetrance in Arab-Berber patients from Tunisia: a case-control genetic study.
Lancet neurology 2008;7(7):591-4.
-
2008: Ross Owen A; Wu Yih-Ru; Lee Mei-Ching; Funayama Manabu; Chen Meng-Ling; Soto Alexandra I; Mata Ignacio F; Lee-Chen Guey-Jen; Chen Chiung Mei; Tang Michelle; Zhao Yi; Hattori Nobutaka; Farrer Matthew J; Tan Eng-King; Wu Ruey-Meei
Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease.
Annals of neurology 2008;64(1):88-92.
-
2008: Ross Owen A; Braithwaite Adam T; Skipper Lisa M; Kachergus Jennifer; Hulihan Mary M; Middleton Frank A; Nishioka Kenya; Fuchs Julia; Gasser Thomas; Maraganore Demetrius M; Adler Charles H; Larvor Lydie; Chartier-Harlin Marie-Christine; Nilsson Christer; Langston J William; Gwinn Katrina; Hattori Nobutaka; Farrer Matthew J
Genomic investigation of alpha-synuclein multiplication and parkinsonism.
Annals of neurology 2008;63(6):743-50.
-
2008: Haugarvoll K; Rademakers R; Kachergus J M; Nuytemans K; Ross O A; Gibson J M; Tan E-K; Gaig C; Tolosa E; Goldwurm S; Guidi M; Riboldazzi G; Brown L; Walter U; Benecke R; Berg D; Gasser T; Theuns J; Pals P; Cras P; De Deyn P Paul; Engelborghs S; Pickut B; Uitti R J; Foroud T; Nichols W C; Hagenah J; Klein C; Samii A; Zabetian C P; Bonifati V; Van Broeckhoven C; Farrer M J; Wszolek Z K
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease.
Neurology 2008;70(16 Pt 2):1456-60.
-
2008: Brighina L; Frigerio R; Schneider N K; Lesnick T G; de Andrade M; Cunningham J M; Farrer M J; Lincoln S J; Checkoway H; Rocca W A; Maraganore D M
Alpha-synuclein, pesticides, and Parkinson disease: a case-control study.
Neurology 2008;70(16 Pt 2):1461-9.
-
2008: Wider C; Melquist S; Hauf M; Solida A; Cobb S A; Kachergus J M; Gass J; Coon K D; Baker M; Cannon A; Stephan D A; Schorderet D F; Ghika J; Burkhard P R; Kapatos G; Hutton M; Farrer M J; Wszolek Z K; Vingerhoets F J G
Study of a Swiss dopa-responsive dystonia family with a deletion in GCH1: redefining DYT14 as DYT5.
Neurology 2008;70(16 Pt 2):1377-83.
-
2008: Vilariño-Güell Carles; Farrer Matthew J; Lin Siong-Chi
A genetic risk factor for periodic limb movements in sleep.
The New England journal of medicine 2008;358(4):425-7.
-
2008: Lewis Jada; Melrose Heather; Bumcrot David; Hope Andrew; Zehr Cynthia; Lincoln Sarah; Braithwaite Adam; He Zhen; Ogholikhan Sina; Hinkle Kelly; Kent Caroline; Toudjarska Ivanka; Charisse Klaus; Braich Ravi; Pandey Rajendra K; Heckman Michael; Maraganore Demetrius M; Crook Julia; Farrer Matthew J
In vivo silencing of alpha-synuclein using naked siRNA.
Molecular neurodegeneration 2008;3():19.
-
2008: Farrer Matthew
The Genetics and molecular biology of alpha-synuclein.
Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn 2008;89():313-9.
-
2008: Myhre Ronny; Klungland Helge; Farrer Matthew J; Aasly Jan O
Genetic association study of synphilin-1 in idiopathic Parkinson's disease.
BMC medical genetics 2008;9():19.
-
2007: González-Fernández María C; Lezcano Elena; Ross Owen A; Gómez-Esteban Juan C; Gómez-Busto Fernando; Velasco Fernando; Alvarez-Alvarez Maite; Rodríguez-Martínez María B; Ciordia Roberto; Zarranz Juan J; Farrer Matthew J; Mata Ignacio F; de Pancorbo Marian M
Lrrk2-associated parkinsonism is a major cause of disease in Northern Spain.
Parkinsonism & related disorders 2007;13(8):509-15.
-
2007: Farrer Matthew J
Lrrk2 in the limelight!
Neurology 2007;69(18):1732-3.
-
2007: Winkler S; Hagenah J; Lincoln S; Heckman M; Haugarvoll K; Lohmann-Hedrich K; Kostic V; Farrer M; Klein C
alpha-Synuclein and Parkinson disease susceptibility.
Neurology 2007;69(18):1745-50.
-
2007: Dächsel Justus C; Taylor Julie P; Mok Su San; Ross Owen A; Hinkle Kelly M; Bailey Rachel M; Hines Jacob H; Szutu Jennifer; Madden Benjamin; Petrucelli Leonard; Farrer Matthew J
Identification of potential protein interactors of Lrrk2.
Parkinsonism & related disorders 2007;13(7):382-5.
-
2007: Ross Owen A; Haugarvoll Kristoffer; Stone Jeremy T; Heckman Michael G; White Linda R; Aasly Jan O; Mark Gibson J; Lynch Timothy; Wszolek Zbigniew K; Uitti Ryan J; Farrer Matthew J
Lack of evidence for association of Parkin promoter polymorphism (PRKN-258) with increased risk of Parkinson's disease.
Parkinsonism & related disorders 2007;13(7):386-8.
-
2007: Taylor Juliet M; Song Yun Ju C; Huang Yue; Farrer Matthew J; Delatycki Martin B; Halliday Glenda M; Lockhart Paul J
Parkin Co-Regulated Gene (PACRG) is regulated by the ubiquitin-proteasomal system and is present in the pathological features of Parkinsonian diseases.
Neurobiology of disease 2007;27(2):238-47.
-
2007: Lincoln Sarah J; Ross Owen A; Milkovic Nicole M; Dickson Dennis W; Rajput Alex; Robinson Christopher A; Papapetropoulos Spiridon; Mash Deborah C; Farrer Matthew J
Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy.
Parkinsonism & related disorders 2007;13(6):340-2.
-
2007: Perez-Pastene Carolina; Cobb Stephanie A; Díaz-Grez Fernando; Hulihan Mary M; Miranda Marcelo; Venegas Pablo; Godoy Osvaldo Trujillo; Kachergus Jennifer M; Ross Owen A; Layson Luis; Farrer Matthew J; Segura-Aguilar Juan
Lrrk2 mutations in South America: A study of Chilean Parkinson's disease.
Neuroscience letters 2007;422(3):193-7.
-
2007: Melrose H L; Kent C B; Taylor J P; Dachsel J C; Hinkle K M; Lincoln S J; Mok S S; Culvenor J G; Masters C L; Tyndall G M; Bass D I; Ahmed Z; Andorfer C A; Ross O A; Wszolek Z K; Delldonne A; Dickson D W; Farrer M J
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
Neuroscience 2007;147(4):1047-58.
-
2007: Baba Y; Baker M C; Le Ber I; Brice A; Maeck L; Kohlhase J; Yasuda M; Stoppe G; Bugiani O; Sperfeld A D; Tsuboi Y; Uitti R J; Farrer M J; Ghetti B; Hutton M L; Wszolek Z K
Clinical and genetic features of families with frontotemporal dementia and parkinsonism linked to chromosome 17 with a P301S tau mutation.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(7):947-50.
-
2007: Brighina Laura; Okubadejo Njide U; Schneider Nicole K; Lesnick Timothy G; de Andrade Mariza; Cunningham Julie M; Farrer Matthew J; Lincoln Sarah J; Rocca Walter A; Maraganore Demetrius M
Beta-synuclein gene variants and Parkinson's disease: a preliminary case-control study.
Neuroscience letters 2007;420(3):229-34.
-
2007: Ross Owen A; Gosal David; Stone Jeremy T; Lincoln Sarah J; Heckman Michael G; Irvine G Brent; Johnston Janet A; Gibson J Mark; Farrer Matthew J; Lynch Timothy
Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease.
Mechanisms of ageing and development 2007;128(5-6):378-82.
-
2007: White Linda R; Toft Mathias; Kvam Sylvia N; Farrer Matthew J; Aasly Jan O
MAPK-pathway activity, Lrrk2 G2019S, and Parkinson's disease.
Journal of neuroscience research 2007;85(6):1288-94.
-
2007: Dächsel Justus C; Ross Owen A; Mata Ignacio F; Kachergus Jennifer; Toft Mathias; Cannon Ashley; Baker Matt; Adamson Jennifer; Hutton Mike; Dickson Dennis W; Farrer Matthew J
Lrrk2 G2019S substitution in frontotemporal lobar degeneration with ubiquitin-immunoreactive neuronal inclusions.
Acta neuropathologica 2007;113(5):601-6.
-
2007: Ross Owen A; Farrer Matthew J; Wu Ruey-Meei
Common variants in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2007;22(6):899-900.
-
2007: Melquist Stacey; Craig David W; Huentelman Matthew J; Crook Richard; Pearson John V; Baker Matt; Zismann Victoria L; Gass Jennifer; Adamson Jennifer; Szelinger Szabolcs; Corneveaux Jason; Cannon Ashley; Coon Keith D; Lincoln Sarah; Adler Charles; Tuite Paul; Calne Donald B; Bigio Eileen H; Uitti Ryan J; Wszolek Zbigniew K; Golbe Lawrence I; Caselli Richard J; Graff-Radford Neill; Litvan Irene; Farrer Matthew J; Dickson Dennis W; Hutton Mike; Stephan Dietrich A
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms.
American journal of human genetics 2007;80(4):769-78.
-
2007: Haugarvoll Kristoffer; Toft Mathias; Ross Owen A; White Linda R; Aasly Jan O; Farrer Matthew J
Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway.
Neuroscience letters 2007;416(3):299-301.
-
2007: Taylor Julie P; Hulihan Mary M; Kachergus Jennifer M; Melrose Heather L; Lincoln Sarah J; Hinkle Kelly M; Stone Jeremy T; Ross Owen A; Hauser Robert; Aasly Jan; Gasser Thomas; Payami Haydeh; Wszolek Zbigniew K; Farrer Matthew J
Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease.
Neurogenetics 2007;8(2):95-102.
-
2007: Baba Yasuhiko; Uitti Ryan J; Boylan Kevin B; Uehara Yoshinari; Yamada Tatsuo; Farrer Matthew J; Couchon Elizabeth; Batish Sat Dev; Wszolek Zbigniew K
Aprataxin (APTX) gene mutations resembling multiple system atrophy.
Parkinsonism & related disorders 2007;13(3):139-42.
-
2007: Fuchs J; Nilsson C; Kachergus J; Munz M; Larsson E-M; Schüle B; Langston J W; Middleton F A; Ross O A; Hulihan M; Gasser T; Farrer M J
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication.
Neurology 2007;68(12):916-22.
-
2007: Haugarvoll Kristoffer; Toft Mathias; Ross Owen A; Stone Jeremy T; Heckman Michael G; White Linda R; Lynch Timothy; Gibson John Mark; Wszolek Zbigniew K; Uitti Ryan J; Aasly Jan O; Farrer Matthew J
ELAVL4, PARK10, and the Celts.
Movement disorders : official journal of the Movement Disorder Society 2007;22(4):585-7.
-
2007: Farrer Matthew J; Stone Jeremy T; Lin Chin-Hsien; Dächsel Justus C; Hulihan Mary M; Haugarvoll Kristoffer; Ross Owen A; Wu Ruey-Meei
Lrrk2 G2385R is an ancestral risk factor for Parkinson's disease in Asia.
Parkinsonism & related disorders 2007;13(2):89-92.
-
2007: Papapetropoulos Spiridon; Farrer Matthew J; Stone Jeremy T; Milkovic Nicole M; Ross Owen A; Calvo Linda; McQuorquodale Donald; Mash Deborah C
Phenotypic associations of tau and ApoE in Parkinson's disease.
Neuroscience letters 2007;414(2):141-4.
-
2007: Whittle A J; Ross O A; Naini A; Gordon P; Mistumoto H; Dächsel J C; Stone J T; Wszolek Z K; Farrer M J; Przedborski S
Pathogenic Lrrk2 substitutions and Amyotrophic lateral sclerosis.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(3):327-9.
-
2007: Toft Mathias; Mata Ignacio F; Ross Owen A; Kachergus Jennifer; Hulihan Mary M; Haugarvoll Kristoffer; Stone Jeremy T; Blazquez Marta; Gibson J Mark; Aasly Jan O; White Linda R; Lynch Timothy; Adler Charles H; Gwinn-Hardy Katrina; Farrer Matthew J
Pathogenicity of the Lrrk2 R1514Q substitution in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2007;22(3):389-92.
-
2007: Toft M; Myhre R; Pielsticker L; White L R; Aasly J O; Farrer M J
PINK1 mutation heterozygosity and the risk of Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2007;78(1):82-4.
-
2007: Dächsel Justus C; Lincoln Sarah J; Gonzalez John; Ross Owen A; Dickson Dennis W; Farrer Matthew J
The ups and downs of alpha-synuclein mRNA expression.
Movement disorders : official journal of the Movement Disorder Society 2007;22(2):293-5.
-
2007: Gosal David; Lynch Timothy; Ross Owen A; Haugarvoll Kristoffer; Farrer Matthew J; Gibson J Mark
Global distribution and reduced penetrance: Lrrk2 R1441C in an Irish Parkinson's disease kindred.
Movement disorders : official journal of the Movement Disorder Society 2007;22(2):291-2.
-
2007: Toft M; Haugarvoll K; Ross O A; Farrer M J; Aasly J O
LRRK2 and Parkinson's disease in Norway.
Acta neurologica Scandinavica. Supplementum 2007;187():72-5.
-
2006: Dächsel Justus C; Mata Ignacio F; Ross Owen A; Taylor Julie P; Lincoln Sarah J; Hinkle Kelly M; Huerta Cecilia; Ribacoba Renee; Blazquez Marta; Alvarez Victoria; Farrer Matthew J
Digenic parkinsonism: investigation of the synergistic effects of PRKN and LRRK2.
Neuroscience letters 2006;410(2):80-4.
-
2006: Rajput A; Dickson D W; Robinson C A; Ross O A; Dächsel J C; Lincoln S J; Cobb S A; Rajput M L; Farrer M J
Parkinsonism, Lrrk2 G2019S, and tau neuropathology.
Neurology 2006;67(8):1506-8.
-
2006: Haugarvoll Kristoffer; Uitti Ryan J; Farrer Matthew J; Wszolek Zbigniew K
LRRK2 gene and tremor-dominant parkinsonism.
Archives of neurology 2006;63(9):1346-7.
-
2006: Ishihara Lianna; Warren Liling; Gibson Rachel; Amouri Rim; Lesage Suzanne; Dürr Alexandra; Tazir Meriem; Wszolek Zbigniew K; Uitti Ryan J; Nichols William C; Griffith Alida; Hattori Nobutaka; Leppert David; Watts Ray; Zabetian Cyrus P; Foroud Tatiana M; Farrer Matthew J; Brice Alexis; Middleton Lefkos; Hentati Faycal
Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations.
Archives of neurology 2006;63(9):1250-4.
-
2006: Papapetropoulos Spiridon; Singer Carlos; Ross Owen A; Toft Mathias; Johnson Joseph L; Farrer Matthew J; Mash Deborah C
Clinical heterogeneity of the LRRK2 G2019S mutation.
Archives of neurology 2006;63(9):1242-6.
-
2006: Baba Yasuhiko; Uitti Ryan J; Farrer Matthew J; Wszolek Zbigniew K
Atypical Parkinsonism and SCA8.
Parkinsonism & related disorders 2006;12(6):396.
-
2006: Maraganore Demetrius M; de Andrade Mariza; Elbaz Alexis; Farrer Matthew J; Ioannidis John P; Krüger Rejko; Rocca Walter A; Schneider Nicole K; Lesnick Timothy G; Lincoln Sarah J; Hulihan Mary M; Aasly Jan O; Ashizawa Tetsuo; Chartier-Harlin Marie-Christine; Checkoway Harvey; Ferrarese Carlo; Hadjigeorgiou Georgios; Hattori Nobutaka; Kawakami Hideshi; Lambert Jean-Charles; Lynch Timothy; Mellick George D; Papapetropoulos Spiridon; Parsian Abbas; Quattrone Aldo; Riess Olaf; Tan Eng-King; Van Broeckhoven Christine;
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.
JAMA : the journal of the American Medical Association 2006;296(6):661-70.
-
2006: Melrose Heather L; Lincoln Sarah J; Tyndall Glenn M; Farrer Matthew J
Parkinson's disease: a rethink of rodent models.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2006;173(2):196-204.
-
2006: Tomiyama Hiroyuki; Li Yuanzhe; Funayama Manabu; Hasegawa Kazuko; Yoshino Hiroyo; Kubo Shin-Ichiro; Sato Kenichi; Hattori Tatsuya; Lu Chin-Song; Inzelberg Rivka; Djaldetti Ruth; Melamed Eldad; Amouri Rim; Gouider-Khouja Neziha; Hentati Faycal; Hatano Yasuko; Wang Mei; Imamichi Yoko; Mizoguchi Koichi; Miyajima Hiroaki; Obata Fumiya; Toda Tatsushi; Farrer Matthew J; Mizuno Yoshikuni; Hattori Nobutaka
Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries.
Movement disorders : official journal of the Movement Disorder Society 2006;21(8):1102-8.
-
2006: Farrer Matthew J; Haugarvoll Kristoffer; Ross Owen A; Stone Jeremy T; Milkovic Nicole M; Cobb Stephanie A; Whittle Andrew J; Lincoln Sarah J; Hulihan Mary M; Heckman Michael G; White Linda R; Aasly Jan O; Gibson J Mark; Gosal David; Lynch Timothy; Wszolek Zbigniew K; Uitti Ryan J; Toft Mathias
Genomewide association, Parkinson disease, and PARK10.
American journal of human genetics 2006;78(6):1084-8; author reply 1092-4.
-
2006: Mata Ignacio F; Wedemeyer William J; Farrer Matthew J; Taylor Julie P; Gallo Kathleen A
LRRK2 in Parkinson's disease: protein domains and functional insights.
Trends in neurosciences 2006;29(5):286-93.
-
2006: Mata I F; Ross O A; Kachergus J; Huerta C; Ribacoba R; Moris G; Blazquez M; Guisasola L M; Salvador C; Martinez C; Farrer M; Alvarez V
LRRK2 mutations are a common cause of Parkinson's disease in Spain.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2006;13(4):391-4.
-
2006: Baba Yasuhiko; Markopoulou Katerina; Putzke John D; Whaley Nathaniel R; Farrer Matthew J; Wszolek Zbigniew K; Uitti Ryan J
Phenotypic commonalities in familial and sporadic Parkinson disease.
Archives of neurology 2006;63(4):579-83.
-
2006: Farrer Matthew James
Genetics of Parkinson disease: paradigm shifts and future prospects.
Nature reviews. Genetics 2006;7(4):306-18.
-
2006: Toft M; Pielsticker L; Ross O A; Aasly J O; Farrer M J
Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population.
Neurology 2006;66(3):415-7.
-
2006: Giasson Benoit I; Covy Jason P; Bonini Nancy M; Hurtig Howard I; Farrer Matthew J; Trojanowski John Q; Van Deerlin Vivianna M
Biochemical and pathological characterization of Lrrk2.
Annals of neurology 2006;59(2):315-22.
-
2006: Ross Owen A; Toft Mathias; Whittle Andrew J; Johnson Joseph L; Papapetropoulos Spiridon; Mash Deborah C; Litvan Irene; Gordon Mark F; Wszolek Zbigniew K; Farrer Matthew J; Dickson Dennis W
Lrrk2 and Lewy body disease.
Annals of neurology 2006;59(2):388-93.
-
2006: Ross O A; Whittle A J; Cobb S A; Hulihan M M; Lincoln S J; Toft M; Farrer M J; Dickson D W
Lrrk2 R1441 substitution and progressive supranuclear palsy.
Neuropathology and applied neurobiology 2006;32(1):23-5.
-
2006: Taylor Julie P; Mata Ignacio F; Farrer Matt J
LRRK2: a common pathway for parkinsonism, pathogenesis and prevention?
Trends in molecular medicine 2006;12(2):76-82.
-
2006: Nishioka Kenya; Hayashi Shin; Farrer Matthew J; Singleton Andrew B; Yoshino Hiroyo; Imai Hisamasa; Kitami Toshiaki; Sato Kenichi; Kuroda Ryu; Tomiyama Hiroyuki; Mizoguchi Koichi; Murata Miho; Toda Tatsushi; Imoto Issei; Inazawa Johji; Mizuno Yoshikuni; Hattori Nobutaka
Clinical heterogeneity of alpha-synuclein gene duplication in Parkinson's disease.
Annals of neurology 2006;59(2):298-309.
-
2006: Mata Ignacio F; Bodkin Cynthia L; Adler Charles H; Lin Siong-Chi; Uitti Ryan J; Farrer Matthew J; Wszolek Zbigniew K
Genetics of restless legs syndrome.
Parkinsonism & related disorders 2006;12(1):1-7.
-
2006: Whaley N R; Uitti R J; Dickson D W; Farrer M J; Wszolek Z K
Clinical and pathologic features of families with LRRK2-associated Parkinson's disease.
Journal of neural transmission. Supplementum 2006;(70):221-9.
-
2006: Melrose H; Lincoln S; Tyndall G; Dickson D; Farrer M
Anatomical localization of leucine-rich repeat kinase 2 in mouse brain.
Neuroscience 2006;139(3):791-4.
-
2005: Dickson Dennis W; Farrer Matthew J
Tau kinases and Parkinson's disease: guilt by association?
Annals of neurology 2005;58(6):819-20.
-
2005: Mata Ignacio F; Kachergus Jennifer M; Taylor Julie P; Lincoln Sarah; Aasly Jan; Lynch Timothy; Hulihan Mary M; Cobb Stephanie A; Wu Ruey-Meei; Lu Chin-Song; Lahoz Carlos; Wszolek Zbigniew K; Farrer Matthew J
Lrrk2 pathogenic substitutions in Parkinson's disease.
Neurogenetics 2005;6(4):171-7.
-
2005: Adams John R; van Netten Hinke; Schulzer Michael; Mak Edwin; Mckenzie Jessamyn; Strongosky Audrey; Sossi Vesna; Ruth Thomas J; Lee Chong S; Farrer Matthew; Gasser Thomas; Uitti Ryan J; Calne Donald B; Wszolek Zbigniew K; Stoessl A Jon
PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.
Brain : a journal of neurology 2005;128(Pt 12):2777-85.
-
2005: Maraganore Demetrius M; de Andrade Mariza; Lesnick Timothy G; Strain Kari J; Farrer Matthew J; Rocca Walter A; Pant P V Krishna; Frazer Kelly A; Cox David R; Ballinger Dennis G
High-resolution whole-genome association study of Parkinson disease.
American journal of human genetics 2005;77(5):685-93.
-
2005: Toft Mathias; Sando Sigrid Botne; Melquist Stacey; Ross Owen A; White Linda R; Aasly Jan O; Farrer Matthew J
LRRK2 mutations are not common in Alzheimer's disease.
Mechanisms of ageing and development 2005;126(11):1201-5.
-
2005: Krygowska-Wajs A; Kachergus J M; Hulihan M M; Farrer M J; Searcy J A; Booij J; Berendse H W; Wolters E Ch; Wszolek Z K
Clinical and genetic evaluation of 8 Polish families with levodopa-responsive parkinsonism.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(11):1487-502.
-
2005: Skipper L; Shen H; Chua E; Bonnard C; Kolatkar P; Tan L C S; Jamora R D; Puvan K; Puong K Y; Zhao Y; Pavanni R; Wong M C; Yuen Y; Farrer M; Liu J J; Tan E K
Analysis of LRRK2 functional domains in nondominant Parkinson disease.
Neurology 2005;65(8):1319-21.
-
2005: Farrer M; Stone J; Mata I F; Lincoln S; Kachergus J; Hulihan M; Strain K J; Maraganore D M
LRRK2 mutations in Parkinson disease.
Neurology 2005;65(5):738-40.
-
2005: Gosal David; Ross Owen A; Wiley Joe; Irvine G Brent; Johnston Janet A; Toft Mathias; Mata Ignacio F; Kachergus Jennifer; Hulihan Mary; Taylor Julie P; Lincoln Sarah J; Farrer Matthew J; Lynch Timothy; Mark Gibson J
Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD.
Parkinsonism & related disorders 2005;11(6):349-52.
-
2005: Ross O A; Farrer M J
Pathophysiology, pleiotrophy and paradigm shifts: genetic lessons from Parkinson's disease.
Biochemical Society transactions 2005;33(Pt 4):586-90.
-
2005: Tan E K; Shen H; Tan L C S; Farrer M; Yew K; Chua E; Jamora R D; Puvan K; Puong K Y; Zhao Y; Pavanni R; Wong M C; Yih Yuen; Skipper L; Liu Jian-Jun
The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients.
Neuroscience letters 2005;384(3):327-9.
-
2005: Mata Ignacio F; Taylor Julie P; Kachergus Jennifer; Hulihan Mary; Huerta Cecilia; Lahoz Carlos; Blazquez Marta; Guisasola Luis M; Salvador Carlos; Ribacoba Renee; Martinez Carmen; Farrer Matthew; Alvarez Victoria
LRRK2 R1441G in Spanish patients with Parkinson's disease.
Neuroscience letters 2005;382(3):309-11.
-
2005: Martinez Maria; Brice Alexis; Vaughan Jenny R; Zimprich Alexander; Breteler Monique M B; Meco Giuseppe; Filla Alessandro; Farrer Matthew J; Bétard Christine; Singleton Andrew; Hardy John; De Michele Giuseppe; Bonifati Vincenzo; Oostra Ben A; Gasser Thomas; Wood Nick W; Dürr Alexandra
Apolipoprotein E4 is probably responsible for the chromosome 19 linkage peak for Parkinson's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;136B(1):72-4.
-
2005: Biancalana Valérie; Toft Mathias; Le Ber Isabelle; Tison François; Scherrer Elisabeth; Thibodeau Stephen; Mandel Jean Louis; Brice Alexis; Farrer Matthew J; Dürr Alexandra
FMR1 premutations associated with fragile X-associated tremor/ataxia syndrome in multiple system atrophy.
Archives of neurology 2005;62(6):962-6.
-
2005: Facheris Maurizio; Strain Kari J; Lesnick Timothy G; de Andrade Mariza; Bower James H; Ahlskog J Eric; Cunningham Julie M; Lincoln Sarah; Farrer Mathew J; Rocca Walter A; Maraganore Demetrius M
UCHL1 is associated with Parkinson's disease: a case-unaffected sibling and case-unrelated control study.
Neuroscience letters 2005;381(1-2):131-4.
-
2005: Baba Yasuhiko; Tsuboi Yoshio; Baker Matthew C; Uitti Ryan J; Hutton Michael L; Dickson Dennis W; Farrer Matthew; Putzke John D; Woodruff Bryan K; Ghetti Bernardino; Murrell Jill R; Boeve Bradley F; Petersen Ronald C; Verpillat Patrice; Brice Alexis; Delisle Marie-Bernadette; Rascol Oliver; Arima Kunimasa; Dysken Maurice W; Yasuda Minoru; Kobayashi Tomonori; Sunohara Nobuhiko; Komure Osamu; Kuno Sadako; Sperfeld Anne D; Stoppe Gabriela; Kohlhase Jürgen; Pickering-Brown Stuart; Neary David; Bugiani Orso; Wszolek Zbigniew K
The effect of tau genotype on clinical features in FTDP-17.
Parkinsonism & related disorders 2005;11(4):205-8.
-
2005: Mata Ignacio F; Alvarez Victoria; Coto Eliecer; Blazquez Marta; Guisasola Luis M; Salvador Carlos; Kachergus Jennifer M; Lincoln Sarah J; Farrer Matthew
Homozygous partial genomic triplication of the parkin gene in early-onset parkinsonism.
Neuroscience letters 2005;380(3):257-9.
-
2005: Aasly Jan O; Toft Mathias; Fernandez-Mata Ignacio; Kachergus Jennifer; Hulihan Mary; White Linda R; Farrer Matthew
Clinical features of LRRK2-associated Parkinson's disease in central Norway.
Annals of neurology 2005;57(5):762-5.
-
2005: Baba Yasuhiko; Uitti Ryan J; Farrer Matthew J; Wszolek Zbigniew K
Sporadic SCA8 mutation resembling corticobasal degeneration.
Parkinsonism & related disorders 2005;11(3):147-50.
-
2005: Toft Mathias; Mata Ignacio F; Kachergus Jennifer M; Ross Owen A; Farrer Matthew J
LRRK2 mutations and Parkinsonism.
Lancet 2005;365(9466):1229-30.
-
2005: Kachergus Jennifer; Mata Ignacio F; Hulihan Mary; Taylor Julie P; Lincoln Sarah; Aasly Jan; Gibson J Mark; Ross Owen A; Lynch Timothy; Wiley Joseph; Payami Haydeh; Nutt John; Maraganore Demetrius M; Czyzewski Krzysztof; Styczynska Maria; Wszolek Zbigniew K; Farrer Matthew J; Toft Mathias
Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations.
American journal of human genetics 2005;76(4):672-80.
-
2005: Mamah Catherine E; Lesnick Timothy G; Lincoln Sarah J; Strain Kari J; de Andrade Mariza; Bower James H; Ahlskog J Eric; Rocca Walter A; Farrer Matthew J; Maraganore Demetrius M
Interaction of alpha-synuclein and tau genotypes in Parkinson's disease.
Annals of neurology 2005;57(3):439-43.
-
2005: Prestel Jürgen; Sharma Manu; Leitner Petra; Zimprich Alexander; Vaughan Jenny R; Dürr Alexandra; Bonifati Vincenzo; De Michele Giuseppe; Hanagasi Hasmet A; Farrer Matthew; Hofer Anne; Asmus Friedrich; Volpe Giampiero; Meco Giuseppe; Brice Alexis; Wood Nicholas W; Müller-Myhsok Bertram; Gasser Thomas;
PARK11 is not linked with Parkinson's disease in European families.
European journal of human genetics : EJHG 2005;13(2):193-7.
-
2005: Toft Mathias; Aasly Jan; Bisceglio Gina; Adler Charles H; Uitti Ryan J; Krygowska-Wajs Anna; Lynch Timothy; Wszolek Zbigniew K; Farrer Matthew J
Parkinsonism, FXTAS, and FMR1 premutations.
Movement disorders : official journal of the Movement Disorder Society 2005;20(2):230-3.
-
2005: Toft Mathias; Farrer Matthew
Premutation alleles and fragile X-associated tremor/ataxia syndrome.
JAMA : the journal of the American Medical Association 2005;293(3):296; author reply 296-7.
-
2005: Wu Ruey-Meei; Bounds Rebecca; Lincoln Sarah; Hulihan Mary; Lin Chin-Hsien; Hwu Wuh-Liang; Chen Judy; Gwinn-Hardy Katrina; Farrer Matt
Parkin mutations and early-onset parkinsonism in a Taiwanese cohort.
Archives of neurology 2005;62(1):82-7.
-
2004: Morris Huw R; Steele John C; Crook Richard; Wavrant-De Vrièze Fabienne; Onstead-Cardinale Luisa; Gwinn-Hardy Katrina; Wood Nick W; Farrer Matthew; Lees Andrew J; McGeer P L; Siddique Teepu; Hardy John; Perez-Tur Jordi
Genome-wide analysis of the parkinsonism-dementia complex of Guam.
Archives of neurology 2004;61(12):1889-97.
-
2004: Martinez M; Brice A; Vaughan J R; Zimprich A; Breteler M M B; Meco G; Filla A; Farrer M J; Bétard C; Hardy J; De Michele G; Bonifati V; Oostra B; Gasser T; Wood N W; Dürr A;
Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease.
Journal of medical genetics 2004;41(12):900-7.
-
2004: Zimprich Alexander; Biskup Saskia; Leitner Petra; Lichtner Peter; Farrer Matthew; Lincoln Sarah; Kachergus Jennifer; Hulihan Mary; Uitti Ryan J; Calne Donald B; Stoessl A Jon; Pfeiffer Ronald F; Patenge Nadja; Carbajal Iria Carballo; Vieregge Peter; Asmus Friedrich; Müller-Myhsok Bertram; Dickson Dennis W; Meitinger Thomas; Strom Tim M; Wszolek Zbigniew K; Gasser Thomas
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Neuron 2004;44(4):601-7.
-
2004: Pals Philippe; Lincoln Sarah; Manning Jonathan; Heckman Michael; Skipper Lisa; Hulihan Mary; Van den Broeck Marleen; De Pooter Tim; Cras Patrick; Crook Julia; Van Broeckhoven Christine; Farrer Matt J
alpha-Synuclein promoter confers susceptibility to Parkinson's disease.
Annals of neurology 2004;56(4):591-5.
-
2004: Skipper Lisa; Wilkes Kristen; Toft Mathias; Baker Matthew; Lincoln Sarah; Hulihan Mary; Ross Owen A; Hutton Mike; Aasly Jan; Farrer Matthew
Linkage disequilibrium and association of MAPT H1 in Parkinson disease.
American journal of human genetics 2004;75(4):669-77.
-
2004: Chartier-Harlin Marie-Christine; Kachergus Jennifer; Roumier Christophe; Mouroux Vincent; Douay Xavier; Lincoln Sarah; Levecque Clotilde; Larvor Lydie; Andrieux Joris; Hulihan Mary; Waucquier Nawal; Defebvre Luc; Amouyel Philippe; Farrer Matthew; Destée Alain
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease.
Lancet 2004;364(9440):1167-9.
-
2004: Lockhart Paul J; Bounds Rebecca; Hulihan Mary; Kachergus Jennifer; Lincoln Sarah; Lin Chin-Hsien; Wu Ruey-Meei; Farrer Matthew J
Lack of mutations in DJ-1 in a cohort of Taiwanese ethnic Chinese with early-onset parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2004;19(9):1065-9.
-
2004: Hope Andrew D; Myhre Ronny; Kachergus Jennifer; Lincoln Sarah; Bisceglio Gina; Hulihan Mary; Farrer Matthew J
Alpha-synuclein missense and multiplication mutations in autosomal dominant Parkinson's disease.
Neuroscience letters 2004;367(1):97-100.
-
2004: Maraganore D M; Wilkes K; Lesnick T G; Strain K J; de Andrade M; Rocca W A; Bower J H; Ahlskog J E; Lincoln S; Farrer M J
A limited role for DJ1 in Parkinson disease susceptibility.
Neurology 2004;63(3):550-3.
-
2004: West Andrew B; Kapatos Gregory; O'Farrell Casey; Gonzalez-de-Chavez Fanny; Chiu Kelvin; Farrer Matthew J; Maidment Nigel T
N-myc regulates parkin expression.
The Journal of biological chemistry 2004;279(28):28896-902.
-
2004: Wiley Joseph; Lynch Timothy; Lincoln Sarah; Skipper Lisa; Hulihan Mary; Gosal David; Bisceglio Gina; Kachergus Jennifer; Hardy John; Farrer Matthew J
Parkinson's disease in Ireland: clinical presentation and genetic heterogeneity in patients with parkin mutations.
Movement disorders : official journal of the Movement Disorder Society 2004;19(6):677-81.
-
2004: Furtado Sarah; Payami Haydeh; Lockhart Paul J; Hanson Melissa; Nutt John G; Singleton Andrew A; Singleton Amanda; Bower Jamel; Utti Ryan J; Bird Thomas D; de la Fuente-Fernandez Raul; Tsuboi Yoshio; Klimek Mary L; Suchowersky Oksana; Hardy John; Calne Donald B; Wszolek Zbigniew K; Farrer Matthew; Gwinn-Hardy Katrina; Stoessl A Jon
Profile of families with parkinsonism-predominant spinocerebellar ataxia type 2 (SCA2).
Movement disorders : official journal of the Movement Disorder Society 2004;19(6):622-9.
-
2004: Munhoz Renato P; Sa Daniel S; Rogaeva Ekaterina; Salehi-Rad Shabnam; Sato Christine; Medeiros Helena; Farrer Matthew; Lang Anthony E
Clinical findings in a large family with a parkin ex3delta40 mutation.
Archives of neurology 2004;61(5):701-4.
-
2004: Wszolek Z K; Pfeiffer R F; Tsuboi Y; Uitti R J; McComb R D; Stoessl A J; Strongosky A J; Zimprich A; Müller-Myhsok B; Farrer M J; Gasser T; Calne D B; Dickson D W
Autosomal dominant parkinsonism associated with variable synuclein and tau pathology.
Neurology 2004;62(9):1619-22.
-
2004: Mata Ignacio F; Lockhart Paul J; Farrer Matthew J
Parkin genetics: one model for Parkinson's disease.
Human molecular genetics 2004;13 Spec No 1():R127-33.
-
2004: Lockhart P J; Lincoln S; Hulihan M; Kachergus J; Wilkes K; Bisceglio G; Mash D C; Farrer M J
DJ-1 mutations are a rare cause of recessively inherited early onset parkinsonism mediated by loss of protein function.
Journal of medical genetics 2004;41(3):e22.
-
2004: Lockhart Paul J; Hulihan Mary; Lincoln Sarah; Hussey Jennifer; Skipper Lisa; Bisceglio Gina; Wilkes Kristen; Farrer Matthew J
Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis.
DNA sequence : the journal of DNA sequencing and mapping 2004;15(1):9-14.
-
2004: Farrer Matt; Kachergus Jennifer; Forno Lysia; Lincoln Sarah; Wang Deng-Shun; Hulihan Mary; Maraganore Demetrius; Gwinn-Hardy Katrina; Wszolek Zbigniew; Dickson Dennis; Langston J William
Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications.
Annals of neurology 2004;55(2):174-9.
-
2004: Lockhart Paul J; O'Farrell Casey A; Farrer Matthew J
It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG).
Movement disorders : official journal of the Movement Disorder Society 2004;19(1):101-4.
-
2004: Edland Steven D; Slager Susan; Farrer Matthew
Genetic association studies in Alzheimer's disease research: challenges and opportunities.
Statistics in medicine 2004;23(2):169-78.
-
2004: Zimprich Alexander; Müller-Myhsok Bertram; Farrer Matthew; Leitner Petra; Sharma Manu; Hulihan Mary; Lockhart Paul; Strongosky Audrey; Kachergus Jennifer; Calne Donald B; Stoessl Jon; Uitti Ryan J; Pfeiffer Ronald F; Trenkwalder Claudia; Homann Nikolaus; Ott Erwin; Wenzel Karoline; Asmus Friedrich; Hardy John; Wszolek Zbigniew; Gasser Thomas
The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval.
American journal of human genetics 2004;74(1):11-9.
-
2004: Lockhart Paul J; Kachergus Jennifer; Lincoln Sarah; Hulihan Mary; Bisceglio Gina; Thomas Natalie; Dickson Dennis; Farrer Matthew J
Multiplication of the alpha-synuclein gene is not a common disease mechanism in Lewy body disease.
Journal of molecular neuroscience : MN 2004;24(3):337-42.
-
2003: Lincoln Sarah J; Maraganore Demetrius M; Lesnick Timothy G; Bounds Rebecca; de Andrade Mariza; Bower James H; Hardy John A; Farrer Matthew J
Parkin variants in North American Parkinson's disease: cases and controls.
Movement disorders : official journal of the Movement Disorder Society 2003;18(11):1306-11.
-
2003: Maraganore Demetrius M; Farrer Matthew J; Lesnick Timothy G; de Andrade Mariza; Bower James H; Hernandez Dena; Hardy John A; Rocca Walter A
Case-control study of the alpha-synuclein interacting protein gene and Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2003;18(11):1233-9.
-
2003: Houlden H; Lincoln S; Farrer M; Cleland P G; Hardy J; Orrell R W
Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic.
Neurology 2003;61(10):1423-6.
-
2003: Cookson Mark R; Lockhart Paul J; McLendon Chris; O'Farrell Casey; Schlossmacher Michael; Farrer Matthew J
RING finger 1 mutations in Parkin produce altered localization of the protein.
Human molecular genetics 2003;12(22):2957-65.
-
2003: Singleton A B; Farrer M; Johnson J; Singleton A; Hague S; Kachergus J; Hulihan M; Peuralinna T; Dutra A; Nussbaum R; Lincoln S; Crawley A; Hanson M; Maraganore D; Adler C; Cookson M R; Muenter M; Baptista M; Miller D; Blancato J; Hardy J; Gwinn-Hardy K
alpha-Synuclein locus triplication causes Parkinson's disease.
Science (New York, N.Y.) 2003;302(5646):841.
-
2003: Tan Louis C; Tanner Caroline M; Chen Rong; Chan Piu; Farrer Matthew; Hardy John; Langston J William
Marked variation in clinical presentation and age of onset in a family with a heterozygous parkin mutation.
Movement disorders : official journal of the Movement Disorder Society 2003;18(7):758-63.
-
2003: Maraganore Demetrius M; de Andrade Mariza; Lesnick Timothy G; Farrer Matthew J; Bower James H; Hardy John A; Rocca Walter A
Complex interactions in Parkinson's disease: a two-phased approach.
Movement disorders : official journal of the Movement Disorder Society 2003;18(6):631-6.
-
2003: Marx Frank P; Holzmann Carsten; Strauss Karsten M; Li Lei; Eberhardt Olaf; Gerhardt Ellen; Cookson Mark R; Hernandez Dena; Farrer Matt J; Kachergus Jennifer; Engelender Simone; Ross Christopher A; Berger Klaus; Schöls Ludger; Schulz Jörg B; Riess Olaf; Krüger Rejko
Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.
Human molecular genetics 2003;12(11):1223-31.
-
2003: Lincoln S; Wiley J; Lynch T; Langston J W; Chen R; Lang A; Rogaeva E; Sa D S; Munhoz R P; Harris J; Marder K; Klein C; Bisceglio G; Hussey J; West A; Hulihan M; Hardy J; Farrer M
Parkin-proven disease: common founders but divergent phenotypes.
Neurology 2003;60(10):1605-10.
-
2003: Baptista Melisa J; O'Farrell Casey; Daya Sneha; Ahmad Rili; Miller David W; Hardy John; Farrer Matthew J; Cookson Mark R
Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines.
Journal of neurochemistry 2003;85(4):957-68.
-
2003: West Andrew B; Gonzalez-de-Chavez Fanny; Wilkes Kristen; O'Farrell Casey; Farrer Matthew J
Parkin is not regulated by the unfolded protein response in human neuroblastoma cells.
Neuroscience letters 2003;341(2):139-42.
-
2003: Rawal N; Periquet M; Lohmann E; Lücking C B; Teive H A; Ambrosio G; Raskin S; Lincoln S; Hattori N; Guimaraes J; Horstink M W I M; Dos Santos Bele W; Brousolle E; Destée A; Mizuno Y; Farrer M; Deleuze J-F; De Michele G; Agid Y; Dürr A; Brice A;
New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism.
Neurology 2003;60(8):1378-81.
-
2003: Payami Haydeh; Nutt John; Gancher Steven; Bird Thomas; McNeal Melissa Gonzales; Seltzer William K; Hussey Jennifer; Lockhart Paul; Gwinn-Hardy Katrina; Singleton Amanda A; Singleton Andrew B; Hardy John; Farrer Matthew
SCA2 may present as levodopa-responsive parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2003;18(4):425-9.
-
2003: Krygowska-Wajs Anna; Hussey Jennifer M; Hulihan Mary; Farrer Matthew J; Tsuboi Yoshio; Uitti Ryan J; Wszolek Zbigniew K
Two large Polish kindreds with levodopa-responsive Parkinsonism not linked to known Parkinsonian genes and loci.
Parkinsonism & related disorders 2003;9(4):193-200.
-
2003: West Andrew B; Lockhart Paul J; O'Farell Casey; Farrer Matthew J
Identification of a novel gene linked to parkin via a bi-directional promoter.
Journal of molecular biology 2003;326(1):11-9.
-
2003: Wszolek Zbigniew K; Tsuboi Yoshio; Farrer Mathew; Uitti Ryan J; Hutton Mike L
Hereditary tauopathies and parkinsonism.
Advances in neurology 2003;91():153-63.
-
2002: Petrucelli Leonard; O'Farrell Casey; Lockhart Paul J; Baptista Melisa; Kehoe Kathryn; Vink Liselot; Choi Peter; Wolozin Benjamin; Farrer Matthew; Hardy John; Cookson Mark R
Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons.
Neuron 2002;36(6):1007-19.
-
2002: Walker Ruth H; Friedman Joseph; Wiener Jill; Hobler Ronald; Gwinn-Hardy Katrina; Adam Amanda; DeWolfe Jennifer; Gibbs Rebecca; Baker Matt; Farrer Matt; Hutton Mike; Hardy John
A family with a tau P301L mutation presenting with parkinsonism.
Parkinsonism & related disorders 2002;9(2):121-3.
-
2002: Goudreau John L; Maraganore Demetrius M; Farrer Matthew J; Lesnick Timothy G; Singleton Andrew B; Bower James H; Hardy John A; Rocca Walter A
Case-control study of dopamine transporter-1, monoamine oxidase-B, and catechol-O-methyl transferase polymorphisms in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2002;17(6):1305-11.
-
2002: Furtado S; Farrer M; Tsuboi Y; Klimek M L; de la Fuente-Fernández R; Hussey J; Lockhart P; Calne D B; Suchowersky O; Stoessl A J; Wszolek Z K
SCA-2 presenting as parkinsonism in an Alberta family: clinical, genetic, and PET findings.
Neurology 2002;59(10):1625-7.
-
2002: Skipper Lisa; Farrer Matt
Parkinson's genetics: molecular insights for the new millennium.
Neurotoxicology 2002;23(4-5):503-14.
-
2002: West Andrew B; Maraganore Demetrius; Crook Julia; Lesnick Tim; Lockhart Paul J; Wilkes Kristen M; Kapatos Gregory; Hardy John A; Farrer Matt J
Functional association of the parkin gene promoter with idiopathic Parkinson's disease.
Human molecular genetics 2002;11(22):2787-92.
-
2002: Subramony S H; Hernandez Dena; Adam Amanda; Smith-Jefferson Stephanie; Hussey Jennifer; Gwinn-Hardy Katrina; Lynch Timothy; McDaniel Olga; Hardy John; Farrer Matt; Singleton Andrew
Ethnic differences in the expression of neurodegenerative disease: Machado-Joseph disease in Africans and Caucasians.
Movement disorders : official journal of the Movement Disorder Society 2002;17(5):1068-71.
-
2002: Wu Ruey-Meei; Shan Din-E; Sun Chen-Ming; Liu Ren-Shyan; Hwu Wuh-Liang; Tai Chun-Hwei; Hussey Jennifer; West Andrew; Gwinn-Hardy Katrina; Hardy John; Chen Judy; Farrer Matt; Lincoln Sarah
Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations.
Movement disorders : official journal of the Movement Disorder Society 2002;17(4):670-5.
-
2002: West Andrew; Periquet Magali; Lincoln Sarah; Lücking Christoph B; Nicholl David; Bonifati Vincenzo; Rawal Nina; Gasser Thomas; Lohmann Ebba; Deleuze Jean-François; Maraganore Demetrius; Levey Allan; Wood Nick; Dürr Alexandra; Hardy John; Brice Alexis; Farrer Matt;
Complex relationship between Parkin mutations and Parkinson disease.
American journal of medical genetics 2002;114(5):584-91.
-
2002: de Silva Rohan; Farrer Matt
Tau neurotoxicity without the lesions: a fly challenges a tangled web.
Trends in neurosciences 2002;25(7):327-9.
-
2002: Maraganore Demetrius M; Farrer Matthew J; McDonnell Shannon K; Elbaz Alexis; Schaid Daniel J; Hardy John A; Rocca Walter A
Case-control study of estrogen receptor gene polymorphisms in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2002;17(3):509-12.
-
2002: Farrer Matt; Skipper Lisa; Berg Marianne; Bisceglio Gina; Hanson Melissa; Hardy John; Adam Amanda; Gwinn-Hardy Katrina; Aasly Jan
The tau H1 haplotype is associated with Parkinson's disease in the Norwegian population.
Neuroscience letters 2002;322(2):83-6.
-
2002: Lockhart Paul J; Holtom Benjamin; Lincoln Sarah; Hussey Jennifer; Zimprich Alexander; Gasser Thomas; Wszolek Zbigniew K; Hardy John; Farrer Matthew J
The human sideroflexin 5 (SFXN5) gene: sequence, expression analysis and exclusion as a candidate for PARK3.
Gene 2002;285(1-2):229-37.
-
2002: Racette B A; Rundle M; Wang J C; Goate A; Saccone N L; Farrer M; Lincoln S; Hussey J; Smemo S; Lin J; Suarez B; Parsian A; Perlmutter J S
A multi-incident, Old-Order Amish family with PD.
Neurology 2002;58(4):568-74.
-
2002: Farrer Matt; Hardy John; Hutton Mike; Maraganore Demetrius; Tsuboi Yoshio; Wszolek Zbigniew K
Identifying genetic factors in Parkinson disease.
JAMA : the journal of the American Medical Association 2002;287(6):715-6.
-
2002: Nicholl D J; Vaughan J R; Khan N L; Ho S L; Aldous D E W; Lincoln S; Farrer M; Gayton J D; Davis M B; Piccini P; Daniel S E; Lennox G G; Brooks D J; Williams A C; Wood N W
Two large British kindreds with familial Parkinson's disease: a clinico-pathological and genetic study.
Brain : a journal of neurology 2002;125(Pt 1):44-57.
-
2002: Gwinn-Hardy Katrina; Farrer Matt
Parkinson's genetics: an embarrassment of riches.
Annals of neurology 2002;51(1):7-8.
-
2002: Hussey Jennifer; Lockhart Paul J; Seltzer William; Wszolek Zbigniew K; Payami Haydeh; Hanson Melissa; Gwinn-Hardy Katrina; Farrer Matt
Accurate determination of ataxin-2 polyglutamine expansion in patients with intermediate-range repeats.
Genetic testing 2002;6(3):217-20.
-
2001: O'Farrell C; Murphy D D; Petrucelli L; Singleton A B; Hussey J; Farrer M; Hardy J; Dickson D W; Cookson M R
Transfected synphilin-1 forms cytoplasmic inclusions in HEK293 cells.
Brain research. Molecular brain research 2001;97(1):94-102.
-
2001: Maraganore D M; Hernandez D G; Singleton A B; Farrer M J; McDonnell S K; Hutton M L; Hardy J A; Rocca W A
Case-Control study of the extended tau gene haplotype in Parkinson's disease.
Annals of neurology 2001;50(5):658-61.
-
2001: West A B; Zimprich A; Lockhart P J; Farrer M; Singleton A; Holtom B; Lincoln S; Hofer A; Hill L; Müller-Myhsok B; Wszolek Z K; Hardy J; Gasser T
Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes.
European journal of human genetics : EJHG 2001;9(9):659-66.
-
2001: Farrer M; Chan P; Chen R; Tan L; Lincoln S; Hernandez D; Forno L; Gwinn-Hardy K; Petrucelli L; Hussey J; Singleton A; Tanner C; Hardy J; Langston J W
Lewy bodies and parkinsonism in families with parkin mutations.
Annals of neurology 2001;50(3):293-300.
-
2001: West A; Farrer M; Petrucelli L; Cookson M; Lockhart P; Hardy J
Identification and characterization of the human parkin gene promoter.
Journal of neurochemistry 2001;78(5):1146-52.
-
2001: Farrer M; Maraganore D M; Lockhart P; Singleton A; Lesnick T G; de Andrade M; West A; de Silva R; Hardy J; Hernandez D
alpha-Synuclein gene haplotypes are associated with Parkinson's disease.
Human molecular genetics 2001;10(17):1847-51.
-
2001: Matsuoka Y; Vila M; Lincoln S; McCormack A; Picciano M; LaFrancois J; Yu X; Dickson D; Langston W J; McGowan E; Farrer M; Hardy J; Duff K; Przedborski S; Di Monte D A
Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter.
Neurobiology of disease 2001;8(3):535-9.
-
2001: Farrer M; Destée A; Levecque C; Singleton A; Engelender S; Becquet E; Mouroux V; Richard F; Defebvre L; Crook R; Hernandez D; Ross C A; Hardy J; Amouyel P; Chartier-Harlin M C
Genetic analysis of synphilin-1 in familial Parkinson's disease.
Neurobiology of disease 2001;8(2):317-23.
-
2001: Dickson D; Farrer M; Lincoln S; Mason R P; Zimmerman T R; Golbe L I; Hardy J
Pathology of PD in monozygotic twins with a 20-year discordance interval.
Neurology 2001;56(7):981-2.
-
2001: Periquet M; Lücking C; Vaughan J; Bonifati V; Dürr A; De Michele G; Horstink M; Farrer M; Illarioshkin S N; Pollak P; Borg M; Brefel-Courbon C; Denefle P; Meco G; Gasser T; Breteler M M; Wood N; Agid Y; Brice A;
Origin of the mutations in the parkin gene in Europe: exon rearrangements are independent recurrent events, whereas point mutations may result from Founder effects.
American journal of human genetics 2001;68(3):617-26.
-
2001: Gwinn-Hardy K; Singleton A; O'Suilleabhain P; Boss M; Nicholl D; Adam A; Hussey J; Critchley P; Hardy J; Farrer M
Spinocerebellar ataxia type 3 phenotypically resembling parkinson disease in a black family.
Archives of neurology 2001;58(2):296-9.
-
2000: Ko L; Mehta N D; Farrer M; Easson C; Hussey J; Yen S; Hardy J; Yen S H
Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein.
Journal of neurochemistry 2000;75(6):2546-54.
-
2000: Baptista M J; Fairbrother U L; Howard C M; Farrer M J; Davies G E; Trikka D; Maratou K; Redington A; Greve G; Njølstad P R; Kessling A M
Heterotrisomy, a significant contributing factor to ventricular septal defect associated with Down syndrome?
Human genetics 2000;107(5):476-82.
-
2000: Farrer M; Destée T; Becquet E; Wavrant-De Vrièze F; Mouroux V; Richard F; Defebvre L; Lincoln S; Hardy J; Amouyel P; Chartier-Harlin M C
Linkage exclusion in French families with probable Parkinson' s disease.
Movement disorders : official journal of the Movement Disorder Society 2000;15(6):1075-83.
-
2000: Gwinn-Hardy K; Chen J Y; Liu H C; Liu T Y; Boss M; Seltzer W; Adam A; Singleton A; Koroshetz W; Waters C; Hardy J; Farrer M
Spinocerebellar ataxia type 2 with parkinsonism in ethnic Chinese.
Neurology 2000;55(6):800-5.
-
2000: Maraganore D M; Farrer M J; Hardy J A; McDonnell S K; Schaid D J; Rocca W A
Case-control study of debrisoquine 4-hydroxylase, N-acetyltransferase 2, and apolipoprotein E gene polymorphisms in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2000;15(4):714-9.
-
2000: Gwinn-Hardy K; Mehta N D; Farrer M; Maraganore D; Muenter M; Yen S H; Hardy J; Dickson D W
Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p.
Acta neuropathologica 2000;99(6):663-72.
-
2000: Gwinn-Hardy K A; Crook R; Lincoln S; Adler C H; Caviness J N; Hardy J; Farrer M
A kindred with Parkinson's disease not showing genetic linkage to established loci.
Neurology 2000;54(2):504-7.
-
1999: Maraganore D M; Farrer M J; Hardy J A; Lincoln S J; McDonnell S K; Rocca W A
Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson's disease.
Neurology 1999;53(8):1858-60.
-
1999: Dickson D W; Liu W; Hardy J; Farrer M; Mehta N; Uitti R; Mark M; Zimmerman T; Golbe L; Sage J; Sima A; D'Amato C; Albin R; Gilman S; Yen S H
Widespread alterations of alpha-synuclein in multiple system atrophy.
The American journal of pathology 1999;155(4):1241-51.
-
1999: Harhangi B S; Farrer M J; Lincoln S; Bonifati V; Meco G; De Michele G; Brice A; Dürr A; Martinez M; Gasser T; Bereznai B; Vaughan J R; Wood N W; Hardy J; Oostra B A; Breteler M M
The Ile93Met mutation in the ubiquitin carboxy-terminal-hydrolase-L1 gene is not observed in European cases with familial Parkinson's disease.
Neuroscience letters 1999;270(1):1-4.
-
1999: Lincoln S; Crook R; Chartier-Harlin M C; Gwinn-Hardy K; Baker M; Mouroux V; Richard F; Becquet E; Amouyel P; Destée A; Hardy J; Farrer M
No pathogenic mutations in the beta-synuclein gene in Parkinson's disease.
Neuroscience letters 1999;269(2):107-9.
-
1999: Ostrerova N; Petrucelli L; Farrer M; Mehta N; Choi P; Hardy J; Wolozin B
alpha-Synuclein shares physical and functional homology with 14-3-3 proteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(14):5782-91.
-
1999: Lincoln S; Vaughan J; Wood N; Baker M; Adamson J; Gwinn-Hardy K; Lynch T; Hardy J; Farrer M
Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase gene in familial Parkinson's disease.
Neuroreport 1999;10(2):427-9.
-
1999: Lincoln S; Gwinn-Hardy K; Goudreau J; Chartier-Harlin M C; Baker M; Mouroux V; Richard F; Destée A; Becquet E; Amouyel P; Lynch T; Hardy J; Farrer M
No pathogenic mutations in the persyn gene in Parkinson's disease.
Neuroscience letters 1999;259(1):65-6.
-
1999: Farrer M; Gwinn-Hardy K; Muenter M; DeVrieze F W; Crook R; Perez-Tur J; Lincoln S; Maraganore D; Adler C; Newman S; MacElwee K; McCarthy P; Miller C; Waters C; Hardy J
A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor.
Human molecular genetics 1999;8(1):81-5.
-
1999: Farrer M; Gwinn-Hardy K; Hutton M; Hardy J
The genetics of disorders with synuclein pathology and parkinsonism.
Human molecular genetics 1999;8(10):1901-5.
-
1998: Crook R; Verkkoniemi A; Perez-Tur J; Mehta N; Baker M; Houlden H; Farrer M; Hutton M; Lincoln S; Hardy J; Gwinn K; Somer M; Paetau A; Kalimo H; Ylikoski R; Pöyhönen M; Kucera S; Haltia M
A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1.
Nature medicine 1998;4(4):452-5.
-
1998: Vaughan J R; Farrer M J; Wszolek Z K; Gasser T; Durr A; Agid Y; Bonifati V; DeMichele G; Volpe G; Lincoln S; Breteler M; Meco G; Brice A; Marsden C D; Hardy J; Wood N W
Sequencing of the alpha-synuclein gene in a large series of cases of familial Parkinson's disease fails to reveal any further mutations. The European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD).
Human molecular genetics 1998;7(4):751-3.
-
1998: Hardy J; Pérez-Tur J; Baker M; Farrer M; Crook R; Hutton M; Johnson W G; Gwinn K; Muenter M; Rocca W A; Maraganore D
Exclusion of genetic linkage to 4q21-23 and 17q21 in a family with Lewy body parkinsonism.
American journal of medical genetics 1998;81(2):166-71.
-
1998: Farrer M; Wavrant-De Vrieze F; Crook R; Boles L; Perez-Tur J; Hardy J; Johnson W G; Steele J; Maraganore D; Gwinn K; Lynch T
Low frequency of alpha-synuclein mutations in familial Parkinson's disease.
Annals of neurology 1998;43(3):394-7.
-
1998: Prasher V P; Farrer M J; Kessling A M; Fisher E M; West R J; Barber P C; Butler A C
Molecular mapping of Alzheimer-type dementia in Down's syndrome.
Annals of neurology 1998;43(3):380-3.
-
1997: Lynch T; Farrer M; Hutton M; Hardy J
Genetics of Parkinson's disease.
Science (New York, N.Y.) 1997;278(5341):1212-3.
-
1997: Baker M; Kwok J B; Kucera S; Crook R; Farrer M; Houlden H; Isaacs A; Lincoln S; Onstead L; Hardy J; Wittenberg L; Dodd P; Webb S; Hayward N; Tannenberg T; Andreadis A; Hallupp M; Schofield P; Dark F; Hutton M
Localization of frontotemporal dementia with parkinsonism in an Australian kindred to chromosome 17q21-22.
Annals of neurology 1997;42(5):794-8.
-
1997: Farrer M J; Crayton L; Davies G E; Oliver C; Powell J; Holland A J; Kessling A M
Allelic variability in D21S11, but not in APP or APOE, is associated with cognitive decline in Down syndrome.
Neuroreport 1997;8(7):1645-9.
-
1995: Davies G E; Howard C M; Farrer M J; Coleman M M; Bennett L B; Cullen L M; Wyse R K; Burn J; Williamson R; Kessling A M
Genetic variation in the COL6A1 region is associated with congenital heart defects in trisomy 21 (Down's syndrome).
Annals of human genetics 1995;59(Pt 3):253-69.
-
1994: Davies G E; Howard C M; Farrer M J; Coleman M M; Cullen L M; Williamson R; Wyse R K; Kessling A M
Unusual genotypes in the COL6A1 gene in parents of children with trisomy 21 and major congenital heart defects.
Human genetics 1994;93(4):443-6.
-
1993: Howard C M; Davies G E; Farrer M J; Cullen L M; Coleman M M; Williamson R; Wyse R K; Palmer R; Kessling A M
Meiotic crossing-over in nondisjoined chromosomes of children with trisomy 21 and a congenital heart defect.
American journal of human genetics 1993;53(2):462-71.
-
1993: Davies G E; Howard C M; Gorman L M; Farrer M J; Holland A J; Williamson R; Kessling A M
Polymorphisms and linkage disequilibrium in the COL6A1 and COL6A2 gene cluster: novel DNA polymorphisms in the region of a candidate gene for congenital heart defects in Down's syndrome.
Human genetics 1993;90(5):521-5.
Sign-in to see more
