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Nicolas Fasel

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Molecular Sequence Data

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Genes & Molecular Sequences

Amino Acid Sequences

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Cutaneous Leishmaniasis

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Publications

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Tiffany Weinkopff; Haroun Zangger; Floriane Auderset; Aldina Barral; Nicolas Fasel; Yazmin Hauyon-La Torre; Anita Mariotto; Steffen Schuster; Gregoire Simon; Fabienne Tacchini-Cottier
Role of Toll-Like Receptor 9 Signaling in Experimental Leishmania braziliensis Infection.
M-A Hartley; K Kohl; Catherine Ronet; Nicolas Fasel
The therapeutic potential of immune cross-talk in leishmaniasis.
Haroun Zangger; Patrick Bastien; Stephen M Beverley; Patrik Castiglioni; Chantal Desponds; Mary-Anne Hartley; F Matthew Kuhlmann; Norbert Müller; Laurent Parmentier; Francine Pratlong; Florence Prevel; John Robinson; Catherine Ronet; Nancy G Saravia; Nicolas Fasel
Detection of Leishmania RNA virus in Leishmania parasites.

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All Publications

2013: Tiffany Weinkopff; Haroun Zangger; Floriane Auderset; Aldina Barral; Nicolas Fasel; Yazmin Hauyon-La Torre; Anita Mariotto; Steffen Schuster; Gregoire Simon; Fabienne Tacchini-Cottier
Role of Toll-Like Receptor 9 Signaling in Experimental Leishmania braziliensis Infection.
Infection and immunity 2013;81(5):1575-84.
2013: M-A Hartley; K Kohl; Catherine Ronet; Nicolas Fasel
The therapeutic potential of immune cross-talk in leishmaniasis.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2013;19(2):119-30.
2013: Haroun Zangger; Patrick Bastien; Stephen M Beverley; Patrik Castiglioni; Chantal Desponds; Mary-Anne Hartley; F Matthew Kuhlmann; Norbert Müller; Laurent Parmentier; Francine Pratlong; Florence Prevel; John Robinson; Catherine Ronet; Nancy G Saravia; Nicolas Fasel
Detection of Leishmania RNA virus in Leishmania parasites.
PLoS neglected tropical diseases 2013;7(1):e2006.
2012: Mary-Anne Hartley; Catherine Ronet; Nicolas Fasel
Backseat drivers: the hidden influence of microbial viruses on disease.
Current opinion in microbiology 2012;15(4):538-45.
2012: Mary-Anne Hartley; Catherine Ronet; Haroun Zangger; Stephen M Beverley; Nicolas Fasel
Leishmania RNA virus: when the host pays the toll.
Frontiers in cellular and infection microbiology 2012;2():99.
2011: Catherine Ronet; Stephen M Beverley; Nicolas Fasel
[Mucocutaneous leishmaniasis and an undesired passenger].
Médecine sciences : M/S 2011;27(11):924-6.
2011: Annette Ives; Catherine Ronet; Florence Prevel; Giulia Ruzzante; Silvia Fuertes-Marraco; Frederic Schutz; Haroun Zangger; Melanie Revaz-Breton; Lon-Fye Lye; Suzanne M Hickerson; Stephen M Beverley; Hans Acha-Orbea; Pascal Launois; Nicolas Fasel; Slavica Masina
Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis.
Science (New York, N.Y.) 2011;331(6018):775-8.
2011: Benoît Meslin; Abdoul H Beavogui; Nicolas Fasel; Stéphane Picot
Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death.
PloS one 2011;6(8):e23867.
2011: Silvia A Fuertes Marraco; Annette Ives; Elisa S Jansen; Slavica Masina; Lorraine A O'Reilly; Pascal Schneider; Clare L Scott; Ken Shortman; Andreas Strasser; David Vremec; Philippe Bouillet; Nicolas Fasel; Hans Acha-Orbea
Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.
PloS one 2011;6(6):e20189.
2011: Benoît Meslin; Habib Zalila; Nicolas Fasel; Stephane Picot; Anne-Lise Bienvenu
Are protozoan metacaspases potential parasite killers?
Parasites & vectors 2011;4():26.
2011: Habib Zalila; Iveth J González; Amal Kuendig El-Fadili; Maria Belen Delgado; Chantal Desponds; Cédric Schaff; Nicolas Fasel
Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major.
Molecular microbiology 2011;79(1):222-39.
2010: A K El-Fadili; H Zangger; Chantal Desponds; I J Gonzalez; H Zalila; Cédric Schaff; A Ives; S Masina; Jeremy C Mottram; Nicolas Fasel
Cathepsin B-like and cell death in the unicellular human pathogen Leishmania.
Cell death & disease 2010;1():e71.
2008: Fabien Rebeaud; Stephan Hailfinger; Anita Posevitz-Fejfar; Myriam Tapernoux; Roger Moser; Daniel Rueda; Olivier Gaide; Montserrat Guzzardi; Emanuela M Iancu; Nathalie Rufer; Nicolas Fasel; Margot Thome
The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
Nature immunology 2008;9(3):272-81.
2008: Audrey Ambit; Nicolas Fasel; Graham H Coombs; Jeremy C Mottram
An essential role for the Leishmania major metacaspase in cell cycle progression.
Cell death and differentiation 2008;15(1):113-22.
2007: Javier Moreno; Javier Nieto; Slavica Masina; Carmen Cañavate; Israel Cruz; Carmen Chicharro; E Carrillo; S Napp; Christophe D Reymond; P M Kaye; Deborah Smith; Nicolas Fasel; Jorge Alvar
Immunization with H1, HASPB1 and MML Leishmania proteins in a vaccine trial against experimental canine leishmaniasis.
Vaccine 2007;25(29):5290-300.
2007: Slavica Masina; Haroun Zangger; Denis Rivier; Nicolas Fasel
Histone H1 regulates chromatin condensation in Leishmania parasites.
Experimental parasitology 2007;116(1):83-7.
2007: Iveth J González; Chantal Desponds; Cédric Schaff; Jeremy C Mottram; Nicolas Fasel
Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity.
International journal for parasitology 2007;37(2):161-72.
2006: Nathalie Acestor; Slavica Masina; Annette Ives; John Walker; Nancy G Saravia; Nicolas Fasel
Resistance to oxidative stress is associated with metastasis in mucocutaneous leishmaniasis.
The Journal of infectious diseases 2006;194(8):1160-7.
2006: John Walker; Nathalie Acestor; Rafael Gongora; Manfredo Quadroni; Iris Segura; Nicolas Fasel; Nancy G Saravia
Comparative protein profiling identifies elongation factor-1beta and tryparedoxin peroxidase as factors associated with metastasis in Leishmania guyanensis.
Molecular and biochemical parasitology 2006;145(2):254-64.
2004: Geneviève Perrenoud; F Messerli; Anne-Christine Thierry; Nicola Beltraminelli; Pascal Cousin; Nicolas Fasel; Véronique Vallet; Stéphane Demotz; Michel A Duchosal; Corinne Moulon
A recombinant rubella virus E1 glycoprotein as a rubella vaccine candidate.
Vaccine 2004;23(4):480-8.
2004: Sima Rafati; Ali Hatef Salmanian; Tahere Taheri; Slavica Masina; Cédric Schaff; Yasaman Taslimi; Nicolas Fasel
Type I signal peptidase from Leishmania is a target of the immune response in human cutaneous and visceral leishmaniasis.
Molecular and biochemical parasitology 2004;135(1):13-20.
2004: Séverine Monnerat; Santiago Martinez-Calvillo; Elizabeth A Worthey; Peter J Myler; Kenneth D Stuart; Nicolas Fasel
Genomic organization and gene expression in a chromosomal region of Leishmania major.
Molecular and biochemical parasitology 2004;134(2):233-43.
2004: Alireza Nakhaee; Tahere Taheri; Mohammad Taghikhani; Mehdi Mohebali; Ali Hatef Salmanian; Nicolas Fasel; Sima Rafati
Humoral and cellular immune responses against Type I cysteine proteinase of Leishmania infantum are higher in asymptomatic than symptomatic dogs selected from a naturally infected population.
Veterinary parasitology 2004;119(2-3):107-23.
2003: J-N Volle; G Chambon; A Sayah; Christophe D Reymond; Nicolas Fasel; Martin A M Gijs
Enhanced sensitivity detection of protein immobilization by fluorescent interference on oxidized silicon.
Biosensors & bioelectronics 2003;19(5):457-64.
2003: Slavica Masina; Michael M Gicheru; Stéphane Demotz; Nicolas Fasel
Protection against cutaneous leishmaniasis in outbred vervet monkeys using a recombinant histone H1 antigen.
The Journal of infectious diseases 2003;188(8):1250-7.
2003: Sabina I Belli; Séverine Monnerat; Cédric Schaff; Slavica Masina; Tanja Noll; Peter J Myler; Kenneth Stuart; Nicolas Fasel
Sense and antisense transcripts in the histone H1 (HIS-1) locus of Leishmania major.
International journal for parasitology 2003;33(9):965-75.
2003: Rafael Góngora; Nathalie Acestor; Manfredo Quadroni; Nicolas Fasel; Nancy G Saravia; John Walker
Mapping the proteome of Leishmania Viannia parasites using two-dimensional polyacrylamide gel electrophoresis and associated technologies.
Biomédica : revista del Instituto Nacional de Salud 2003;23(2):153-60.
2003: Sima Rafati; Alireza Nakhaee; Tahere Taheri; Andishe Ghashghaii; Ali Hatef Salmanian; Maribel Jimenez; Mehdi Mohebali; Slavica Masina; Nicolas Fasel
Expression of cysteine proteinase type I and II of Leishmania infantum and their recognition by sera during canine and human visceral leishmaniasis.
Experimental parasitology 2003;103(3-4):143-51.
2002: Caroline Johnson-Léger; michel AURRAND-LIONS; Nicola Beltraminelli; Nicolas Fasel; Beat A Imhof
Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration.
Blood 2002;100(7):2479-86.
2002: H Zangger; Jeremy C Mottram; Nicolas Fasel
Cell death in Leishmania induced by stress and differentiation: programmed cell death or necrosis?
Cell death and differentiation 2002;9(10):1126-39.
2002: Nathalie Acestor; Slavica Masina; John Walker; Nancy G Saravia; Nicolas Fasel; Manfredo Quadroni
Establishing two-dimensional gels for the analysis of Leishmania proteomes.
Proteomics 2002;2(7):877-9.
2001: Stéphane Demotz; Corinne Moulon; Mario Roggero; Nicolas Fasel; Slavica Masina
Native-like, long synthetic peptides as components of sub-unit vaccines: practical and theoretical considerations for their use in humans.
Molecular immunology 2001;38(6):415-22.
2001: A C Thierry; S Pinaud; N Bigler; Geneviève Perrenoud; B Denis; Mario Roggero; Nicolas Fasel; Corinne Moulon; Stéphane Demotz
Long synthetic peptides as biologically active proteins: the example of the chemokines.
Biologicals : journal of the International Association of Biological Standardization 2001;29(3-4):259-63.
2001: Sima Rafati; Ali Hatef Salmanian; Tahere Taheri; M Vafa; Nicolas Fasel
A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major.
Vaccine 2001;19(25-26):3369-75.
2001: Sima Rafati; Ali Hatef Salmanian; K Hashemi; Cédric Schaff; Sabina I Belli; Nicolas Fasel
Identification of Leishmania major cysteine proteinases as targets of the immune response in humans.
Molecular and biochemical parasitology 2001;113(1):35-43.
2000: Miguel X van Bemmelen; C Beghdadi-Rais; Chantal Desponds; E Vargas; Sócrates Herrera; Christophe D Reymond; Nicolas Fasel
Expression and one-step purification of Plasmodium proteins in dictyostelium.
Molecular and biochemical parasitology 2000;111(2):377-90.
1999: N Solioz; U Blum-Tirouvanziam; R Jacquet; Sima Rafati; Giampietro Corradin; Jacques Mauël; Nicolas Fasel
The protective capacities of histone H1 against experimental murine cutaneous leishmaniasis.
Vaccine 1999;18(9-10):850-9.
1999: Sabina I Belli; A Formenton; Tanja Noll; Alasdair Ivens; R Jacquet; Chantal Desponds; D Hofer; Nicolas Fasel
Leishmania major: histone H1 gene expression from the sw3 locus.
Experimental parasitology 1999;91(2):151-60.
1998: C Rais-Beghdadi; Mario Roggero; Nicolas Fasel; Christophe D Reymond
Purification of recombinant proteins by chemical removal of the affinity tag.
Applied biochemistry and biotechnology 1998;74(2):95-103.
1997: Tanja Noll; Chantal Desponds; Sabina I Belli; T A Glaser; Nicolas Fasel
Histone H1 expression varies during the Leishmania major life cycle.
Molecular and biochemical parasitology 1997;84(2):215-27.
1996: E Bernasconi; Nicolas Fasel; Riccardo Wittek
Cell surface expression of a functional rubella virus E1 glycoprotein by addition of a GPI anchor.
Journal of cell science 1996;109 ( Pt 6)():1195-201.
1995: Mario Roggero; B Filippi; P Church; S L Hoffman; U Blum-Tirouvanziam; J A Lopez; Fulvio Esposito; H Matile; Christophe D Reymond; Nicolas Fasel
Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein.
Molecular immunology 1995;32(17-18):1301-9.
1995: Nicole Deglon; A Wilson; Chantal Desponds; P Laurent; Claude Bron; Nicolas Fasel
Fatty acids regulate Thy-1 antigen mRNA stability in T lymphocyte precursors.
European journal of biochemistry / FEBS 1995;231(3):687-96.
1995: U Blum-Tirouvanziam; Catherine Servis; A Habluetzel; Danila Valmori; Ying Men; Fulvio Esposito; L Del Nero; N Holmes; Nicolas Fasel; Giampietro Corradin
Localization of HLA-A2.1-restricted T cell epitopes in the circumsporozoite protein of Plasmodium falciparum.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3922-31.
1995: POULAIN-GODEFROY Odile; Robert Hirt; Nicolas Fasel; J P Kraehenbühl
The polymeric immunoglobulin receptor: signals for polarized expression.
Advances in experimental medicine and biology 1995;371A():217-20.
1994: U Blum-Tirouvanziam; C Beghdadi-Rais; Mario Roggero; Danila Valmori; S Bertholet; Claude Bron; Nicolas Fasel; Giampietro Corradin
Elicitation of specific cytotoxic T cells by immunization with malaria soluble synthetic polypeptides.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):4134-41.
1994: Nicolas Fasel; Nicole Deglon; C Beghdadi-Rais; R Law; Claude Bron; R Wall
Minimal membrane and secreted mu poly(A) signals specify developmentally-regulated immunoglobulin heavy chain mRNA ratios without RNA splicing.
Molecular immunology 1994;31(7):563-6.
1994: Nicolas Fasel; H Stark; Claude Bron; C Beghdadi-Rais
A trap system for the isolation of amino acid sequences inducing GPI anchor addition.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):189-93.
1994: Robert Hirt; Nicolas Fasel; J P Kraehenbuhl
Inducible protein expression using a glucocorticoid-sensitive vector.
Methods in cell biology 1994;43 Pt A():247-62.
1993: Nicolas Fasel; D Robyr; J Mauel; T A Glaser
Identification of a histone H1-like gene expressed in Leishmania major.
Molecular and biochemical parasitology 1993;62(2):321-3.
1993: Sally Corradin; Nicolas Fasel; Y Buchmüller-Rouiller; Adriana Ransijn; J Smith; Jacques Mauël
Induction of macrophage nitric oxide production by interferon-gamma and tumor necrosis factor-alpha is enhanced by interleukin-10.
European journal of immunology 1993;23(8):2045-8.
1993: C Beghdadi-Rais; M Schreyer; M Rousseaux; P Borel; R J Eisenberg; Gary cohen; Claude Bron; Nicolas Fasel
Carboxyl terminus structural requirements for glycosyl-phosphatidylinositol anchor addition to cell surface proteins.
Journal of cell science 1993;105 ( Pt 3)():831-40.
1992: Nicolas Fasel; M Rousseaux; Nicole Deglon; H L Govan; R Law; Claude Bron; R Wall
Membrane mu poly(A) signal and 3' flanking sequences function as a transcription terminator for immunoglobulin-encoding genes.
Gene 1992;122(2):297-304.
1992: Nicolas Fasel; C Begdadi-Rais; M Bernard; Claude Bron; Giampietro Corradin; Christophe D Reymond
Dictyostelium discoideum as an expression host for the circumsporozoite protein of Plasmodium falciparum.
Gene 1992;111(2):157-63.
1992: Robert Hirt; POULAIN-GODEFROY Odile; J Billotte; J P Kraehenbuhl; Nicolas Fasel
Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector.
Gene 1992;111(2):199-206.
1992: Nicolas Fasel; Nicole Deglon
Multi-level regulation of Thy-1 antigen expression in mouse T lymphomas.
Immunogenetics 1992;35(2):126-30.
1991: Nicolas Fasel; Nicole Deglon; M Rousseaux; C Beghdadi-Rais; M Bernard; Claude Bron
Evaluation of somatic cell variants deficient in glycosylphosphatidyl-inositol anchoring as candidates for genetic correction.
Cell biology international reports 1991;15(11):1051-64.
1991: Nicolas Fasel; M Bernard; Nicole Deglon; M Rousseaux; R J Eisenberg; Claude Bron; Gary cohen
Isolation from mouse fibroblasts of a cDNA encoding a new form of the fibroblast growth factor receptor (flg).
Biochemical and biophysical research communications 1991;178(1):8-15.
1991: Nicole Deglon; A Krapp; Claude Bron; Nicolas Fasel
Translocation of the yeast dolichol-phosphate-mannose synthase into microsomal membranes.
Biochemical and biophysical research communications 1991;174(3):1337-42.
1991: Pierre Michetti; R Hirt; Richard Weltzin; Nicolas Fasel; E Schaerer; Marian R Neutra; J P Kraehenbühl
Production and use of monoclonal IgA antibodies complexed with recombinant secretory component for passive mucosal protection.
Advances in experimental medicine and biology 1991;310():183-5.
1989: Nicolas Fasel; M Rousseaux; E Schaerer; M E Medof; M L Tykocinski; Claude Bron
In vitro attachment of glycosyl-inositolphospholipid anchor structures to mouse Thy-1 antigen and human decay-accelerating factor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(18):6858-62.
1987: R Law; M D Kuwabara; M Briskin; Nicolas Fasel; G Hermanson; David S Sigman; Randolph Wall
Protein-binding site at the immunoglobulin mu membrane polyadenylylation signal: possible role in transcription termination.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):9160-4.