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Kym Faull

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Maggie P Y Lam; Edward Lau; David A Liem; Christopher M Ryan; Sarah B Scruggs; Ding Wang; Jun Zhang; Kym F Faull; Tae-Young Kim; Peipei Ping
Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation.
Meelad M Dawlaty; Kym F Faull; Qing Gao; Thuc Le; Zhe Li; Frank Lyko; Benjamin E Powell; Günter Raddatz; Mingjiang Xu; M Inmaculada Barrasa; Achim Breiling; Albert Cheng; Rudolf Jaenisch
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.
Theodore A Sarafian; Puneet Souda; Harry V Vinters; Kym F Faull; Upendra K Kar; Eliezer Masliah; Gary W Mathern; Christopher M Ryan; Julian P Whitelegge; Joseph B Watson
Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein.

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2013: Maggie P Y Lam; Edward Lau; David A Liem; Christopher M Ryan; Sarah B Scruggs; Ding Wang; Jun Zhang; Kym F Faull; Tae-Young Kim; Peipei Ping
Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation.
Journal of proteomics 2013;81():15-23.
2013: Meelad M Dawlaty; Kym F Faull; Qing Gao; Thuc Le; Zhe Li; Frank Lyko; Benjamin E Powell; Günter Raddatz; Mingjiang Xu; M Inmaculada Barrasa; Achim Breiling; Albert Cheng; Rudolf Jaenisch
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.
Developmental cell 2013;24(3):310-23.
2013: Theodore A Sarafian; Puneet Souda; Harry V Vinters; Kym F Faull; Upendra K Kar; Eliezer Masliah; Gary W Mathern; Christopher M Ryan; Julian P Whitelegge; Joseph B Watson
Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein.
PloS one 2013;8(5):e63557.
2013: Sichen Li; Linda M Liau; Jerry J Lou; Heidi S Phillips; Julia Selfridge; Kuan-Chung Wu; Mira Zurayk; Ruihuan Chen; Weidong Chen; Arthur P Chou; Timothy Cloughesy; Yuzhong Deng; Richard G Everson; Kym F Faull; Albert Lai
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation.
Neuro-oncology 2013;15(1):57-68.
2012: Kirill Tsirulnikov; Ritu Vahi; Christopher M Ryan; Natalia Abuladze; Ivo Atanasov; Kym F Faull; Huma Hasnain; Ira Kurtz; Martin Phillips; Alexander Pushkin
Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein.
FEBS letters 2012;586(21):3799-804.
2012: Stephen A Whelan; Julian P Whitelegge; Kym F Faull; Jianbo He; Ming Lu; Romaine E Saxton; Puneet Souda; Helena R Chang
Mass spectrometry (LC-MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid.
Journal of proteome research 2012;11(10):5034-45.
2012: Walter E Babiec; Kym F Faull; Jack L Feldman
Cyclothiazide-induced persistent increase in respiratory-related activity in vitro.
The Journal of physiology 2012;590(Pt 19):4897-915.
2012: Maggie P Y Lam; Edward Lau; Kym F Faull; Tae-Young Kim; Christopher M Ryan; Sarah B Scruggs; Ding Wang; Chenggong Zong; Peipei Ping
An MRM-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue.
Journal of proteomics 2012;75(15):4602-9.
2012: Frédéric Halgand; Joseph A Loo; Puneet Souda; Sara Bassilian; Kym F Faull; D T Wong; Vlad Zabrouskov; Julian P Whitelegge
Defining intact protein primary structures from saliva: a step toward the human proteome project.
Analytical chemistry 2012;84(10):4383-95.
2011: Hongbin Xu; Kym F Faull; Naoko Goto-Inoue; Louis Hermo; Suraj Kadunganattil; Kessiri Kongmanas; Tony Rupar; Charles E Smith; Nongnuj Tanphaichitr
Arylsulfatase A deficiency causes seminolipid accumulation and a lysosomal storage disorder in Sertoli cells.
Journal of lipid research 2011;52(12):2187-97.
2011: Meytal Landau; Jie Liu; Michael Sawaya; Stuart A Sievers; Jorge R Barrio; Kym F Faull; Lin Jiang; Arthur Laganowsky; David Eisenberg
Towards a pharmacophore for amyloid.
PLoS biology 2011;9(6):e1001080.
2011: Thuc Le; Kee-Pyo Kim; Guoping Fan; Kym F Faull
A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples.
Analytical biochemistry 2011;412(2):203-9.
2010: David A Keire; Julian P Whitelegge; Puneet Souda; Kym F Faull; Sara Bassilian; Roger D Reidelberger; Alvin C Haver; Joseph R Reeve
PYY(1-36) is the major form of PYY in rat distal small intestine: quantification using high-resolution mass spectrometry.
Regulatory peptides 2010;165(2-3):151-7.
2010: Kristofor J Webb; Cecilia I Zurita-Lopez; Qais Al-Hadid; Arthur Laganowsky; Brian D Young; Rebecca S Lipson; Puneet Souda; Kym F Faull; Julian P Whitelegge; Steven G Clarke
A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase.
The Journal of biological chemistry 2010;285(48):37598-606.
2010: Victor M Duarte; Eugene Han; Mysore S Veena; Amanda Salvado; Jeffrey D Suh; Li-Jung Liang; Kym F Faull; Eri S Srivatsan; Marilene B Wang
Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma via inhibition of IKKβ protein of the NFκB pathway.
Molecular cancer therapeutics 2010;9(10):2665-75.
2010: Balakumar Thangaraj; Christopher M Ryan; Puneet Souda; Kirsten Krause; Kym F Faull; Andreas P M Weber; Petra Fromme; Julian P Whitelegge
Data-directed top-down Fourier-transform mass spectrometry of a large integral membrane protein complex: photosystem II from Galdieria sulphuraria.
Proteomics 2010;10(20):3644-56.
2010: Michael A Jansen; Jacqueline Kiwata; Jennifer Arceo; Kym F Faull; Grady Hanrahan; Edith Porter
Evolving neural network optimization of cholesteryl ester separation by reversed-phase HPLC.
Analytical and bioanalytical chemistry 2010;397(6):2367-74.
2010: Christopher M Ryan; Puneet Souda; Frédéric Halgand; David T Wong; Joseph A Loo; Kym F Faull; Julian P Whitelegge
Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry.
Journal of the American Society for Mass Spectrometry 2010;21(6):908-17.
2010: Frédéric Halgand; Vlad Zabrouskov; Sara Bassilian; Puneet Souda; David T Wong; Joseph A Loo; Kym F Faull; Julian P Whitelegge
Micro-heterogeneity of human saliva Peptide P-C characterized by high-resolution top-down Fourier-transform mass spectrometry.
Journal of the American Society for Mass Spectrometry 2010;21(5):868-77.
2010: Christopher M Ryan; Puneet Souda; Sara Bassilian; Rachna Ujwal; Jun Zhang; Jeff Abramson; Peipei Ping; Armando Durazo; James U Bowie; S Saif Hasan; Danas Baniulis; William A Cramer; Kym F Faull; Julian P Whitelegge
Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation.
Molecular & cellular proteomics : MCP 2010;9(5):791-803.
2010: Mike C Wolf; Alexander Freiberg; Tinghu Zhang; Zeynep Akyol-Ataman; Andrew Grock; Patrick W Hong; Jianrong Li; Natalya F Watson; Angela Q Fang; Hector C Aguilar; Matteo Porotto; Anna N Honko; Robert Damoiseaux; John P Miller; Sara E Woodson; Steven Chantasirivisal; Vanessa Fontanes; Oscar A Negrete; Paul Krogstad; Asim Dasgupta; Anne Moscona; Lisa E Hensley; Sean Whelan; Kym F Faull; Michael R Holbrook; Michael E Jung; Benhur Lee
A broad-spectrum antiviral targeting entry of enveloped viruses.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):3157-62.
2010: Bryan F Shaw; Demetri T Moustakas; Julian P Whitelegge; Kym F Faull
Taking charge of proteins from neurodegeneration to industrial biotechnology.
Advances in protein chemistry and structural biology 2010;79():127-64.
2010: Lorelei D Shoemaker; Nicholas M Orozco; Daniel Geschwind; Julian P Whitelegge; Kym F Faull; Harley I Kornblum
Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors.
PloS one 2010;5(2):e9121.
2009: Armando Durazo; Bryan F Shaw; Madhuri Chattopadhyay; Kym F Faull; Aram M Nersissian; Joan Selverstone Valentine; Julian P Whitelegge
Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded beta-barrel at physiological temperature.
The Journal of biological chemistry 2009;284(49):34382-9.
2009: Débora L Oliveira; Leonardo Nimrichter; Kildare Miranda; Susana Frases; Kym F Faull; Arturo Casadevall; Marcio Rodrigues
Cryptococcus neoformans cryoultramicrotomy and vesicle fractionation reveals an intimate association between membrane lipids and glucuronoxylomannan.
Fungal genetics and biology : FG & B 2009;46(12):956-63.
2009: Jonathan M Budzik; Catherine B Poor; Kym F Faull; Julian P Whitelegge; Chuan He; Olaf Schneewind
Intramolecular amide bonds stabilize pili on the surface of bacilli.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(47):19992-7.
2009: Jianbo He; Dejun Shen; Debra U Chung; Romaine E Saxton; Julian P Whitelegge; Kym F Faull; Helena R Chang
Tumor proteomic profiling predicts the susceptibility of breast cancer to chemotherapy.
International journal of oncology 2009;35(4):683-92.
2009: Yanju Wang; Wei-Yu Lin; Kan Liu; Rachel J Lin; Matthias Selke; Hartmuth C Kolb; Nangang Zhang; Xing-Zhong Zhao; Michael E Phelps; Clifton K-F Shen; Kym F Faull; Hsian-Rong Tseng
An integrated microfluidic device for large-scale in situ click chemistry screening.
Lab on a chip 2009;9(16):2281-5.
2009: Stephen A Whelan; Ming Lu; Jianbo He; Weihong Yan; Romaine E Saxton; Kym F Faull; Julian P Whitelegge; Helena R Chang
Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers.
Journal of proteome research 2009;8(8):4151-60.
2009: Jaime Bulkacz; Kym F Faull
Multiple extracellular phospholipase activities from Prevotella intermedia.
Anaerobe 2009;15(3):91-4.
2008: David A Keire; Julian P Whitelegge; Sara Bassilian; Kym F Faull; Brian W Wiggins; Omid B Mehdizadeh; Roger D Reidelberger; Alvin C Haver; Ayman I Sayegh; Joseph R Reeve
A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36).
Regulatory peptides 2008;151(1-3):61-70.
2008: Dorothy Wang; Mysore S Veena; Kerry Stevenson; Christopher Tang; Baran Ho; Jeffrey D Suh; Victor M Duarte; Kym F Faull; Kapil Mehta; Eri S Srivatsan; Marilene B Wang
Liposome-encapsulated curcumin suppresses growth of head and neck squamous cell carcinoma in vitro and in xenografts through the inhibition of nuclear factor kappaB by an AKT-independent pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(19):6228-36.
2008: Sara Lanigan-Gerdes; Geraldine Briceno; Alek N Dooley; Kym F Faull; Beth A Lazazzera
Identification of residues important for cleavage of the extracellular signaling peptide CSF of Bacillus subtilis from its precursor protein.
Journal of bacteriology 2008;190(20):6668-75.
2008: Thai Q Do; Safiehkhatoon Moshkani; Patricia Castillo; Suda Anunta; Adelina Pogosyan; Annie Cheung; Beth Marbois; Kym F Faull; William Ernst; Su Ming Chiang; Gary Fujii; Catherine F Clarke; Krishna Foster; Edith Porter
Lipids including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluid.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(6):4177-87.
2008: Araya Anupriwan; Matthias Schenk; Kessiri Kongmanas; Rapeepun Vanichviriyakit; Daniela Costa Santos; Arman Yaghoubian; Fang Liu; Alexander Wu; Trish Berger; Kym F Faull; Porncharn Saitongdee; Prapee Sretarugsa; Nongnuj Tanphaichitr
Presence of arylsulfatase A and sulfogalactosylglycerolipid in mouse ovaries: localization to the corpus luteum.
Endocrinology 2008;149(8):3942-51.
2008: Jonathan M Budzik; Luciano A Marraffini; Puneet Souda; Julian P Whitelegge; Kym F Faull; Olaf Schneewind
Amide bonds assemble pili on the surface of bacilli.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):10215-20.
2008: Aynun N Begum; Mychica R Jones; Giselle P Lim; Takashi Morihara; Peter Kim; Dennis D Heath; Cheryl L Rock; Mila A Pruitt; Fusheng Yang; Beverly Hudspeth; Shuxin Hu; Kym F Faull; Bruce Teter; Gregory M. Cole; Sally A Frautschy
Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease.
The Journal of pharmacology and experimental therapeutics 2008;326(1):196-208.
2008: Laura Franchini; Luigi Panza; Kessiri Kongmanas; Nongnuj Tanphaichitr; Kym F Faull; Fiamma Ronchetti
An efficient and convenient synthesis of deuterium-labelled seminolipid isotopomers and their ESI-MS characterization.
Chemistry and physics of lipids 2008;152(2):78-85.
2008: Elena E Grintsevich; Sabrina A Benchaar; Dora Warshaviak; Pinmanee Boontheung; Frédéric Halgand; Julian P Whitelegge; Kym F Faull; Rachel R Ogorzalek Loo; David Sept; Joseph A Loo; Emil Reisler
Mapping the cofilin binding site on yeast G-actin by chemical cross-linking.
Journal of molecular biology 2008;377(2):395-409.
2008: Nancy A Fujishige; Michelle R Lum; Peter L De Hoff; Julian P Whitelegge; Kym F Faull; Ann Hirsch
Rhizobium common nod genes are required for biofilm formation.
Molecular microbiology 2008;67(3):504-15.
2007: Sara Lanigan-Gerdes; Alek N Dooley; Kym F Faull; Beth A Lazazzera
Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
Molecular microbiology 2007;65(5):1321-33.
2007: Richard T Waldron; Julian P Whitelegge; Kym F Faull; Enrique Rozengurt
Identification of a novel phosphorylation site in c-jun directly targeted in vitro by protein kinase D.
Biochemical and biophysical research communications 2007;356(2):361-7.
2007: Somsak Mitrirattanakul; Héctor E López-Valdés; Jing Liang; Yoshizo Matsuka; Ken Mackie; Kym F Faull; Igor Spigelman
Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence.
Alcoholism, clinical and experimental research 2007;31(5):855-67.
2007: Soshanna Zittin Potter; Haining Zhu; Bryan Francis Shaw; Jorge A Rodriguez; Peter A Doucette; Se Hui Sohn; Armando Durazo; Kym F Faull; Edith Butler Gralla; Aram M Nersissian; Joan Selverstone Valentine
Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein.
Journal of the American Chemical Society 2007;129(15):4575-83.
2007: Ming Lu; Kym F Faull; Julian P Whitelegge; Jianbo He; Dejun Shen; Romaine E Saxton; Helena R Chang
Proteomics and mass spectrometry for cancer biomarker discovery.
Biomarker insights 2007;2():347-60.
2007: Jianbo He; Jeffrey Gornbein; Dejun Shen; Ming Lu; Leonor E Rovai; Hungyi Shau; John Katz; Julian P Whitelegge; Kym F Faull; Helena R Chang
Detection of breast cancer biomarkers in nipple aspirate fluid by SELDI-TOF and their identification by combined liquid chromatography-tandem mass spectrometry.
International journal of oncology 2007;30(1):145-54.
2006: Somsak Mitrirattanakul; Navapoln Ramakul; Andre V Guerrero; Yoshizo Matsuka; Takeshi Ono; Hirotate Iwase; Ken Mackie; Kym F Faull; Igor Spigelman
Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain.
Pain 2006;126(1-3):102-14.
2006: Bryan Francis Shaw; Armando Durazo; Aram M Nersissian; Julian P Whitelegge; Kym F Faull; Joan Selverstone Valentine
Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry.
The Journal of biological chemistry 2006;281(26):18167-76.
2006: Danny H Kim; Shane Que Hee; Andrew J Norris; Kym F Faull; Curtis D Eckhert
Boric acid inhibits adenosine diphosphate-ribosyl cyclase non-competitively.
Journal of chromatography. A 2006;1115(1-2):246-52.
2005: Katherine R Kozak; Feng Su; Julian P Whitelegge; Kym F Faull; Srinivasa Reddy; Robin Farias-Eisner
Characterization of serum biomarkers for detection of early stage ovarian cancer.
Proteomics 2005;5(17):4589-96.
2005: Mo K Kang; Reuben H Kim; Ki-Hyuk Shin; Weiguong Zhong; Kym F Faull; No-Hee Park
Senescence-associated decline in the intranuclear accumulation of hOGG1-alpha and impaired 8-oxo-dG repair activity in senescing normal human oral keratinocytes in vivo.
Experimental cell research 2005;310(1):186-95.
2005: Andrew J Norris; Julian P Whitelegge; Arman Yaghoubian; Jean-René Alattia; Gilbert G Privé; Tatsushi Toyokuni; Hubert Sun; Mai N Brooks; Luigi Panza; Pamela Matto; Federica Compostella; Natascha Remmel; Ralf Klingenstein; Konrad Sandhoff; Claire Fluharty; Arvan L Fluharty; Kym F Faull
A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A.
Journal of lipid research 2005;46(10):2254-64.
2005: A Eugene Pekary; Kym F Faull; Mark Paulson; Robert L Lloyd; Albert Sattin
TRH-like antidepressant peptide, pyroglutamyltyroslyprolineamide, occurs in rat brain.
Journal of mass spectrometry : JMS 2005;40(9):1232-6.
2005: Jorge A Rodriguez; Bryan Francis Shaw; Armando Durazo; Se Hui Sohn; Peter A Doucette; Aram M Nersissian; Kym F Faull; Daryl K Eggers; Ashutosh Tiwari; Lawrence J Hayward; Joan Selverstone Valentine
Destabilization of apoprotein is insufficient to explain Cu,Zn-superoxide dismutase-linked ALS pathogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(30):10516-21.
2005: Beth N Marbois; Peter Gin; Kym F Faull; Wayne W Poon; Peter T Lee; Jeff Strahan; Jennifer N Shepherd; Catherine F Clarke
Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.
The Journal of biological chemistry 2005;280(21):20231-8.
2005: David R Blanco; Cheryl I Champion; Alek Dooley; David L Cox; Julian P Whitelegge; Kym F Faull; Michael A Lovett
A monoclonal antibody that conveys in vitro killing and partial protection in experimental syphilis binds a phosphorylcholine surface epitope of Treponema pallidum.
Infection and immunity 2005;73(5):3083-95.
2005: Adam B Weinglass; Misha Soskine; Jose-Luis Vazquez-Ibar; Julian P Whitelegge; Kym F Faull; H Ronald Kaback; Shimon Schuldiner
Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry.
The Journal of biological chemistry 2005;280(9):7487-92.
2004: Adam B Weinglass; Julian P Whitelegge; Kym F Faull; H Ronald Kaback
Monitoring conformational rearrangements in the substrate-binding site of a membrane transport protein by mass spectrometry.
The Journal of biological chemistry 2004;279(40):41858-65.
2004: Danny H Kim; Kym F Faull; Andrew J Norris; Curtis D Eckhert
Borate-nucleotide complex formation depends on charge and phosphorylation state.
Journal of mass spectrometry : JMS 2004;39(7):743-51.
2004: Julian P Whitelegge; Jonathan E Katz; Katianna A Pihakari; Rebecca Hale; Renato J Aguilera; Stephen M Gómez; Kym F Faull; Dmitrii Vavilin; Willem Vermaas
Subtle modification of isotope ratio proteomics; an integrated strategy for expression proteomics.
Phytochemistry 2004;65(11):1507-15.
2004: Jonathan E Katz; Darren S Dumlao; Jacob I Wasserman; Michael G Lansdown; Michael E Jung; Kym F Faull; Steven Clarke
3-Isopropylmalate is the major endogenous substrate of the Saccharomyces cerevisiae trans-aconitate methyltransferase.
Biochemistry 2004;43(20):5976-86.
2004: Andrew J Norris; Julian P Whitelegge; M Jane Strouse; Kym F Faull; Tatsushi Toyokuni
Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism.
Bioorganic & medicinal chemistry letters 2004;14(3):571-3.
2003: Albert Sattin; A Eugene Pekary; Robert L Lloyd; M Paulson; J A Meyerhoff; Patricia M Hinkle; Kym F Faull
TRH and related peptides: homeostatic regulators of glutamate transmission?
Annals of the New York Academy of Sciences 2003;1003():458-60.
2003: Fayu Chen; Pei-San Ng; Kym F Faull; Rehwa H Lee
Cone photoreceptor betagamma-transducin: posttranslational modification and interaction with phosducin.
Investigative ophthalmology & visual science 2003;44(11):4622-9.
2003: Ho-Hyung Woo; Kym F Faull; Ann Hirsch; Martha C Hawes
Altered life cycle in Arabidopsis plants expressing PsUGT1, a UDP-glucuronosyltransferase-encoding gene from pea.
Plant physiology 2003;133(2):538-48.
2003: Stephen M Gómez; Karl Y Bil'; Renato J Aguilera; John N Nishio; Kym F Faull; Julian P Whitelegge
Transit peptide cleavage sites of integral thylakoid membrane proteins.
Molecular & cellular proteomics : MCP 2003;2(10):1068-85.
2003: Hungyi Shau; G Scott Chandler; Julian P Whitelegge; Jeffrey Gornbein; Kym F Faull; Helena R Chang
Proteomic profiling of cancer biomarkers.
Briefings in functional genomics & proteomics 2003;2(2):147-58.
2003: Julian P Whitelegge; Victoria E Ahn; Andrew J Norris; H Sung; Alan J Waring; RL Stevens; Claire Fluharty; G Prive; Kym F Faull; Arvan L Fluharty
Characterization of a recombinant molecule covalently indistinguishable from human cerebroside-sulfate activator protein (CSAct or Saposin B).
Cellular and molecular biology (Noisy-le-Grand, France) 2003;49(5):799-807.
2003: Danny H Kim; Beth N Marbois; Kym F Faull; Curtis D Eckhert
Esterification of borate with NAD+ and NADH as studied by electrospray ionization mass spectrometry and 11B NMR spectroscopy.
Journal of mass spectrometry : JMS 2003;38(6):632-40.
2003: Adam B Weinglass; Julian P Whitelegge; Yonglin Hu; Gillian E Verner; Kym F Faull; H Ronald Kaback
Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry.
The EMBO journal 2003;22(7):1467-77.
2003: Victoria E Ahn; Kym F Faull; Julian P Whitelegge; Arvan L Fluharty; Gilbert G Privé
Crystal structure of saposin B reveals a dimeric shell for lipid binding.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(1):38-43.
2003: Julian P Whitelegge; Stephen M Gómez; Kym F Faull
Proteomics of membrane proteins.
Advances in protein chemistry 2003;65():271-307.
2003: Victoria E Ahn; Kym F Faull; Julian P Whitelegge; Jason Higginson; Arvan L Fluharty; Gilbert G Privé
Expression, purification, crystallization, and preliminary X-ray analysis of recombinant human saposin B.
Protein expression and purification 2003;27(1):186-93.
2002: Tanya Jonassen; Beth N Marbois; Kym F Faull; Catherine F Clarke; Pamela Larsen
Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria.
The Journal of biological chemistry 2002;277(47):45020-7.
2002: Ganesamoorthy Subbanagounder; Jason W Wong; Hans Lee; Kym F Faull; Elizabeth Miller; Joseph L Witztum; Judith A Berliner
Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta.
The Journal of biological chemistry 2002;277(9):7271-81.
2002: Ben J Glasgow; Adil R Abduragimov; Oktay K Gassymov; Kym F Faull; Taleh N Yusifov; Robert I Lehrer
Characterization of a lipophilin in rabbit tears.
Advances in experimental medicine and biology 2002;506(Pt A):573-80.
2002: Ben J Glasgow; Adil R Abduragimov; Oktay K Gassymov; Taleh N Yusifov; Edward C Ruth; Kym F Faull
Vitamin E associated with the lipocalin fraction of human tears.
Advances in experimental medicine and biology 2002;506(Pt A):567-72.
2002: Stephen M Gómez; John N Nishio; Kym F Faull; Julian P Whitelegge
The chloroplast grana proteome defined by intact mass measurements from liquid chromatography mass spectrometry.
Molecular & cellular proteomics : MCP 2002;1(1):46-59.
2001: Andrew J Norris; Julian P Whitelegge; Kym F Faull; Tatsushi Toyokuni
Kinetic characterization of enzyme inhibitors using electrospray-ionization mass spectrometry coupled with multiple reaction monitoring.
Analytical chemistry 2001;73(24):6024-9.
2001: L T Zhong; A Manzi; Skowronski Evan; Lucia Notterpek; Arvan L Fluharty; Kym F Faull; I Masada; Shahrooz Rabizadeh; M Varsanyi-Nagy; Y Ruan; Justin D Oh; L L Butcher; Dale E Bredesen
A monoclonal antibody that induces neuronal apoptosis binds a metastasis marker.
Cancer research 2001;61(15):5741-8.
2001: Andrew J Norris; Julian P Whitelegge; Kym F Faull; Tatsushi Toyokuni
Analysis of enzyme kinetics using electrospray ionization mass spectrometry and multiple reaction monitoring: fucosyltransferase V.
Biochemistry 2001;40(13):3774-9.
2001: Claire Fluharty; J Johnson; Julian P Whitelegge; Kym F Faull; Arvan L Fluharty
Comparative lipid binding study on the cerebroside sulfate activator (saposin B).
Journal of neuroscience research 2001;63(1):82-9.
2000: Kym F Faull; J Johnson; M J Kim; T To; Julian P Whitelegge; RL Stevens; Claire Fluharty; Arvan L Fluharty
Structure of the asparagine-linked sugar chains of porcine kidney and human urine cerebroside sulfate activator protein.
Journal of mass spectrometry : JMS 2000;35(12):1416-24.
2000: Ganesamoorthy Subbanagounder; Norbert Leitinger; D C Schwenke; J W Wong; Hans Lee; C Rizza; Andrew D Watson; Kym F Faull; Alan M Fogelman; Judith A Berliner
Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2248-54.
2000: Julian P Whitelegge; B Penn; T To; J Johnson; Alan J Waring; M Sherman; RL Stevens; Claire Fluharty; Kym F Faull; Arvan L Fluharty
Methionine oxidation within the cerebroside-sulfate activator protein (CSAct or Saposin B).
Protein science : a publication of the Protein Society 2000;9(9):1618-30.
2000: Mohamad Navab; Susan Hama; C Justin Cooke; Gm Anantharamaiah; Manjula Chaddha; L Jin; Ganesamoorthy Subbanagounder; Kym F Faull; Srinivasa T Reddy; Norman E Miller; Alan M Fogelman
Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1.
Journal of lipid research 2000;41(9):1481-94.
2000: Eric Turk; O Kim; Johannes le Coutre; Julian P Whitelegge; Sepehr Eskandari; JT Lam; Michael Kreman; Guido A Zampighi; Kym F Faull; Ernest M Wright
Molecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters.
The Journal of biological chemistry 2000;275(33):25711-6.
2000: H Liu; Haining Zhu; Daryl K Eggers; Aram M Nersissian; Kym F Faull; JJ Goto; Jingyuan Ai; Joann Sanders-Loehr; Edith Butler Gralla; Joan Selverstone Valentine
Copper(2+) binding to the surface residue cysteine 111 of His46Arg human copper-zinc superoxide dismutase, a familial amyotrophic lateral sclerosis mutant.
Biochemistry 2000;39(28):8125-32.
2000: Diana M Shih; Yu-Rong Xia; Xu-Ping Wang; E Miller; Lawrence W Castellani; Ganesamoorthy Subbanagounder; Hilde Cheroutre; Kym F Faull; Judith A Berliner; Joseph L Witztum; Aldons J Lusis
Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis.
The Journal of biological chemistry 2000;275(23):17527-35.
2000: Johannes le Coutre; Julian P Whitelegge; Adrian Gross; Eric Turk; Ernest M Wright; H Ronald Kaback; Kym F Faull
Proteomics on full-length membrane proteins using mass spectrometry.
Biochemistry 2000;39(15):4237-42.
2000: Kym F Faull; Jason Higginson; Alan J Waring; J Johnson; T To; Julian P Whitelegge; RL Stevens; Claire Fluharty; Arvan L Fluharty
Disulfide connectivity in cerebroside sulfate activator is not necessary for biological activity or alpha-helical content but is necessary for trypsin resistance and strong ligand binding.
Archives of biochemistry and biophysics 2000;376(2):266-74.
2000: Dexter H Howard; Ramin Rafie; A Tiwari; Kym F Faull
Hydroxamate siderophores of Histoplasma capsulatum.
Infection and immunity 2000;68(4):2338-43.
2000: Hung Ton-That; Sarkis K Mazmanian; Kym F Faull; Olaf Schneewind
Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Sortase catalyzed in vitro transpeptidation reaction using LPXTG peptide and NH(2)-Gly(3) substrates.
The Journal of biological chemistry 2000;275(13):9876-81.
2000: Kym F Faull; Jason Higginson; Alan J Waring; T To; Julian P Whitelegge; RL Stevens; Claire Fluharty; Arvan L Fluharty
Hydrogen-deuterium exchange signature of porcine cerebroside sulfate activator protein.
Journal of mass spectrometry : JMS 2000;35(3):392-401.
2000: Beth N Marbois; Kym F Faull; Arvan L Fluharty; Sujna Raval-Fernandes; Leonard H Rome
Analysis of sulfatide from rat cerebellum and multiple sclerosis white matter by negative ion electrospray mass spectrometry.
Biochimica et biophysica acta 2000;1484(1):59-70.
1999: Arvan L Fluharty; C Lombardo; A Louis; RL Stevens; Julian P Whitelegge; Alan J Waring; T To; Claire Fluharty; Kym F Faull
Preparation of the cerebroside sulfate activator (CSAct or saposin B) from human urine.
Molecular genetics and metabolism 1999;68(3):391-403.
1999: Hung Ton-That; G Liu; Sarkis K Mazmanian; Kym F Faull; Olaf Schneewind
Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12424-9.
1999: Kym F Faull; Julian P Whitelegge; Jason Higginson; T To; J Johnson; AN Krutchinsky; K G Standing; Alan J Waring; RL Stevens; Claire Fluharty; Arvan L Fluharty
Cerebroside sulfate activator protein (Saposin B): chromatographic and electrospray mass spectrometric properties.
Journal of mass spectrometry : JMS 1999;34(10):1040-54.
1999: Hamid R Kalhor; A Niewmierzycka; Kym F Faull; Xiaoyi Yao; Stephanie K Grade; Steven Clarke; Peter A Rubenstein
A highly conserved 3-methylhistidine modification is absent in yeast actin.
Archives of biochemistry and biophysics 1999;370(1):105-11.
1999: Julian P Whitelegge; Johannes le Coutre; Jeffrey C Lee; Christian K Engel; Gilbert G Privé; Kym F Faull; H Ronald Kaback
Toward the bilayer proteome, electrospray ionization-mass spectrometry of large, intact transmembrane proteins.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10695-8.
1999: Andrew D Watson; Ganesamoorthy Subbanagounder; Derek S Welsbie; Kym F Faull; Mohamad Navab; Michael E Jung; Alan M Fogelman; Judith A Berliner
Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low density lipoprotein.
The Journal of biological chemistry 1999;274(35):24787-98.
1999: Ganesamoorthy Subbanagounder; Norbert Leitinger; PT Shih; Kym F Faull; Judith A Berliner
Evidence that phospholipid oxidation products and/or platelet-activating factor play an important role in early atherogenesis : in vitro and In vivo inhibition by WEB 2086.
Circulation research 1999;85(4):311-8.
1999: WW Navarre; Hung Ton-That; Kym F Faull; Olaf Schneewind
Multiple enzymatic activities of the murein hydrolase from staphylococcal phage phi11. Identification of a D-alanyl-glycine endopeptidase activity.
The Journal of biological chemistry 1999;274(22):15847-56.
1999: Norbert Leitinger; Andrew D Watson; Susan Hama; BT Ivandic; Jian-Hua Qiao; J Huber; Kym F Faull; David Grass; Mohamad Navab; Alan M Fogelman; Frederick C de Beer; Aldons J Lusis; Judith A Berliner
Role of group II secretory phospholipase A2 in atherosclerosis: 2. Potential involvement of biologically active oxidized phospholipids.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1291-8.
1998: WW Navarre; Hung Ton-That; Kym F Faull; Olaf Schneewind
Anchor structure of staphylococcal surface proteins. II. Cooh-terminal structure of muramidase and amidase-solubilized surface protein.
The Journal of biological chemistry 1998;273(44):29135-42.
1998: Julian P Whitelegge; Cameron B Gundersen; Kym F Faull
Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins.
Protein science : a publication of the Protein Society 1998;7(6):1423-30.
1998: Ben J Glasgow; Adil R Abduragimov; Taleh N Yusifov; Oktay Gasymov; Joseph Horwitz; Wayne L Hubbell; Kym F Faull
A conserved disulfide motif in human tear lipocalins influences ligand binding.
Biochemistry 1998;37(8):2215-25.
1998: Alan J Waring; Y Chen; Kym F Faull; R Stevens; M A Sherman; Arvan L Fluharty
Porcine cerebroside sulfate activator (saposin B) secondary structure: CD, FTIR, and NMR studies.
Molecular genetics and metabolism 1998;63(1):14-25.
1997: KW Zhao; Kym F Faull; Emil D Kakkis; Elizabeth F Neufeld
Carbohydrate structures of recombinant human alpha-L-iduronidase secreted by Chinese hamster ovary cells.
The Journal of biological chemistry 1997;272(36):22758-65.
1997: Hung Ton-That; Kym F Faull; Olaf Schneewind
Anchor structure of staphylococcal surface proteins. A branched peptide that links the carboxyl terminus of proteins to the cell wall.
The Journal of biological chemistry 1997;272(35):22285-92.
1997: Andrew D Watson; Norbert Leitinger; Mohamad Navab; Kym F Faull; Sohvi Hörkkö; Joseph L Witztum; Wulf Palinski; D Schwenke; Robert G Salomon; Wei Sha; Ganesamoorthy Subbanagounder; Alan M Fogelman; Judith A Berliner
Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo.
The Journal of biological chemistry 1997;272(21):13597-607.
1997: Norbert Leitinger; Andrew D Watson; Kym F Faull; Alan M Fogelman; Judith A Berliner
Monocyte binding to endothelial cells induced by oxidized phospholipids present in minimally oxidized low density lipoprotein is inhibited by a platelet activating factor receptor antagonist.
Advances in experimental medicine and biology 1997;433():379-82.
1995: Andrew D Watson; Judith A Berliner; Susan Hama; Bert N La Du; Kym F Faull; Alan M Fogelman; Mohamad Navab
Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein.
The Journal of clinical investigation 1995;96(6):2882-91.
1995: Ben J Glasgow; Adil R Abduragimov; Z T Farahbakhsh; Kym F Faull; Wayne L Hubbell
Tear lipocalins bind a broad array of lipid ligands.
Current eye research 1995;14(5):363-72.
1994: Cameron B Gundersen; A Mastrogiacomo; Kym F Faull; Joy A Umbach
Extensive lipidation of a Torpedo cysteine string protein.
The Journal of biological chemistry 1994;269(30):19197-9.
1993: RL Stevens; Kym F Faull; K A Conklin; B N Green; Arvan L Fluharty
Porcine cerebroside sulfate activator: further structural characterization and disulfide identification.
Biochemistry 1993;32(15):4051-9.
1993: U Bickel; T Yoshikawa; E M Landaw; Kym F Faull; William M Pardridge
Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2618-22.