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Brenda Andrews

Research Profile

Living Beings

Saccharomyces cerevisiae

Chemicals & Drugs

Physiology

Genes & Molecular Sequences

Phenomena

Co-author Network

Publications

TOP 3
Owen Ryan; Tobias Schwarzmüller; A Sellam; Rebecca S Shapiro; Faiza Tebbji; Kyle Tsui; Frederick Vizeacoumar; Malcolm Whiteway; Brenda Andrews; Sondra Bahr; Anastasia Baryshnikova; Doris Cheung; Brian Chin; Michael Costanzo; Leah E Cowen; Michael J Cox; Gerald R Fink; Guri Giaever; David K Gifford; Anne-Claude Gingras; Fabian Istel; Karl Kuchler; Christoph F Kurat; Zhen-Yuan Lin; David Mayhew; Robi D Mitra; Corey Nislow; Todd B Reynolds; Charles Boone
Global gene deletion analysis exploring yeast filamentous growth.
Supipi Kaluarachchi Duffy; Jean-Philippe Lambert; Anastasia Baryshnikova; Yolanda T Chong; Daniel Figeys; Helena Friesen; Brenda Andrews
Exploring the yeast acetylome using functional genomics.
Anastasia Baryshnikova; Brenda Andrews
Neighboring-gene effect: a genetic uncertainty principle.

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All Publications

2012: Owen Ryan; Tobias Schwarzmüller; A Sellam; Rebecca S Shapiro; Faiza Tebbji; Kyle Tsui; Frederick Vizeacoumar; Malcolm Whiteway; Brenda Andrews; Sondra Bahr; Anastasia Baryshnikova; Doris Cheung; Brian Chin; Michael Costanzo; Leah E Cowen; Michael J Cox; Gerald R Fink; Guri Giaever; David K Gifford; Anne-Claude Gingras; Fabian Istel; Karl Kuchler; Christoph F Kurat; Zhen-Yuan Lin; David Mayhew; Robi D Mitra; Corey Nislow; Todd B Reynolds; Charles Boone
Global gene deletion analysis exploring yeast filamentous growth.
Science (New York, N.Y.) 2012;337(6100):1353-6.
2012: Supipi Kaluarachchi Duffy; Jean-Philippe Lambert; Anastasia Baryshnikova; Yolanda T Chong; Daniel Figeys; Helena Friesen; Brenda Andrews
Exploring the yeast acetylome using functional genomics.
Cell 2012;149(4):936-48.
2012: Anastasia Baryshnikova; Brenda Andrews
Neighboring-gene effect: a genetic uncertainty principle.
Nature methods 2012;9(4):341, 343.
2012: Ke Jin; Jingjing Li; Zhijian Li; Renqiang Min; Frederick S Vizeacoumar; Franco Vizeacoumar; Lee Zamparo; Brenda Andrews; Charles Boone; Alessandro Datti; Zhaolei Zhang
PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae.
Nucleic acids research 2012;40(Database issue):D687-94.
2011: Douglas R Boettner; Helena Friesen; Brenda Andrews; Sandra K Lemmon
Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin.
Molecular biology of the cell 2011;22(19):3699-714.
2011: Michael Costanzo; Anastasia Baryshnikova; Chad L Myers; Brenda Andrews; Charles Boone
Charting the genetic interaction map of a cell.
Current opinion in biotechnology 2011;22(1):66-74.
2010: Anastasia Baryshnikova; Michael Costanzo; Yungil Kim; Huiming Ding; Judice Koh; Kiana Toufighi; Ji-Young Youn; Jiongwen Ou; Bryan-Joseph San Luis; Sunayan Bandyopadhyay; Matthew Hibbs; David Hess; Anne-Claude Gingras; Gary D Bader; Olga G Troyanskaya; Grant W Brown; Brenda Andrews; Charles Boone; Chad L Myers
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale.
Nature methods 2010;7(12):1017-24.
2010: Smadar Kahana; Lilach Pnueli; Pinay Kainth; Holly E Sassi; Brenda Andrews; Yona Kassir
Functional dissection of IME1 transcription using quantitative promoter-reporter screening.
Genetics 2010;186(3):829-41.
2010: Pinay Kainth; Brenda Andrews
Illuminating transcription pathways using fluorescent reporter genes and yeast functional genomics.
Transcription 2010;1(2):76-80.
2010: Anastasia Baryshnikova; Michael Costanzo; Scott Dixon; Franco Vizeacoumar; Chad L Myers; Brenda Andrews; Charles Boone
Synthetic genetic array (SGA) analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe.
Methods in enzymology 2010;470():145-79.
2010: Pinay Kainth; Brenda Andrews
Quantitative cell array screening to identify regulators of gene expression.
Briefings in functional genomics 2010;9(1):13-23.
2009: Michael Costanzo; Anastasia Baryshnikova; Corey Nislow; Brenda Andrews; Charles Boone
You too can play with an edge.
Nature methods 2009;6(11):797-8.
2009: Jian Zou; Helena Friesen; Jennifer Larson; Dongqing Huang; Mike Cox; Kelly Tatchell; Brenda Andrews
Regulation of cell polarity through phosphorylation of Bni4 by Pho85 G1 cyclin-dependent kinases in Saccharomyces cerevisiae.
Molecular biology of the cell 2009;20(14):3239-50.
2009: Pinay Kainth; Holly Elizabeth Sassi; Lourdes Peña Castillo; Gordon Chua; Timothy R Hughes; Brenda Andrews
Comprehensive genetic analysis of transcription factor pathways using a dual reporter gene system in budding yeast.
Methods (San Diego, Calif.) 2009;48(3):258-64.
2009: Cheuk Hei Ho; Leslie Magtanong; Sarah L Barker; David Gresham; Shinichi Nishimura; Paramasivam Natarajan; Judice L Y Koh; Justin Porter; Christopher A Gray; Raymond J Andersen; Guri Giaever; Corey Nislow; Brenda Andrews; David Botstein; Todd R Graham; Minoru Yoshida; Charles Boone
A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds.
Nature biotechnology 2009;27(4):369-77.
2009: Scott J Dixon; Michael Costanzo; Anastasia Baryshnikova; Brenda Andrews; Charles Boone
Systematic mapping of genetic interaction networks.
Annual review of genetics 2009;43():601-25.
2007: Dongqing Huang; Helena Friesen; Brenda Andrews
Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast.
Molecular microbiology 2007;66(2):303-14.
2006: Michael Costanzo; Guri Giaever; Corey Nislow; Brenda Andrews
Experimental approaches to identify genetic networks.
Current opinion in biotechnology 2006;17(5):472-80.
2006: Ainslie B Parsons; Andres Lopez; Inmar E Givoni; David E Williams; Christopher A Gray; Justin Porter; Gordon Chua; Richelle Sopko; Renée L Brost; Cheuk-Hei Ho; Jiyi Wang; Troy Ketela; Charles Brenner; Julie A Brill; G Esteban Fernandez; Todd C Lorenz; Gregory S Payne; Satoru Ishihara; Yoshikazu Ohya; Brenda Andrews; Timothy R Hughes; Brendan J Frey; Todd R Graham; Raymond J Andersen; Charles Boone
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.
Cell 2006;126(3):611-25.
2006: Kristin Baetz; Vivien Measday; Brenda Andrews
Revealing hidden relationships among yeast genes involved in chromosome segregation using systematic synthetic lethal and synthetic dosage lethal screens.
Cell cycle (Georgetown, Tex.) 2006;5(6):592-5.
2006: Richelle Sopko; Brenda Andrews
Small open reading frames: not so small anymore.
Genome research 2006;16(3):314-5.
2006: Helena Friesen; Christine Humphries; Yuen Ho; Oliver Schub; Karen Colwill; Brenda Andrews
Characterization of the yeast amphiphysins Rvs161p and Rvs167p reveals roles for the Rvs heterodimer in vivo.
Molecular biology of the cell 2006;17(3):1306-21.
2006: Richelle Sopko; Dongqing Huang; Nicolle Preston; Gordon Chua; Balázs Papp; Kimberly Kafadar; Mike Snyder; Stephen G Oliver; Martha S Cyert; Timothy R Hughes; Charles Boone; Brenda Andrews
Mapping pathways and phenotypes by systematic gene overexpression.
Molecular cell 2006;21(3):319-30.
2006: Teresa Reguly; Ashton Breitkreutz; Lorrie Boucher; Bobby-Joe Breitkreutz; Gary C Hon; Chad L Myers; Ainslie Parsons; Helena Friesen; Rose Oughtred; Amy Tong; Chris Stark; Yuen Ho; David Botstein; Brenda Andrews; Charles Boone; Olga G Troyanskya; Trey Ideker; Kara Dolinski; Nizar N Batada; Mike Tyers
Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae.
Journal of biology 2006;5(4):11.
2005: Jason Ptacek; Geeta Devgan; Gregory A Michaud; Heng Zhu; Xiaowei Zhu; Joseph Fasolo; Hong Guo; Ghil Jona; Ashton Breitkreutz; Richelle Sopko; Rhonda R McCartney; Martin C Schmidt; Najma Rachidi; Soo-Jung Lee; Angie S Mah; Lihao Meng; Michael J R Stark; David F Stern; Claudio de Virgilio; Mike Tyers; Brenda Andrews; Mark Gerstein; Barry Schweitzer; Paul Predki; Michael Snyder
Global analysis of protein phosphorylation in yeast.
Nature 2005;438(7068):679-84.
2005: Vivien Measday; Kristin Baetz; Julie Guzzo; Karen Yuen; Teresa Kwok; Bilal Sheikh; Huiming Ding; Ryo Ueta; Trinh Hoac; Benjamin Cheng; Isabelle Pot; Amy Tong; Yuko Yamaguchi-Iwai; Charles Boone; Philip Hieter; Brenda Andrews
Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(39):13956-61.
2005: Helena Friesen; Karen Colwill; Karen Robertson; Oliver Schub; Brenda Andrews
Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking.
Genetics 2005;170(2):555-68.
2005: Lan V Zhang; Oliver D King; Sharyl L Wong; Debra S Goldberg; Amy Hin Yan Tong; Guillaume Lesage; Brenda Andrews; Howard Bussey; Charles Boone; Frederick P Roth
Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network.
Journal of biology 2005;4(2):6.
2004: Sharyl L Wong; Lan V Zhang; Amy Hin Yan Tong; Zhijian Li; Debra S Goldberg; Oliver D King; Guillaume Lesage; Marc Vidal; Brenda Andrews; Howard Bussey; Charles Boone; Frederick P Roth
Combining biological networks to predict genetic interactions.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15682-7.
2004: Michael Costanzo; Joy L Nishikawa; Xiaojing Tang; Jonathan S Millman; Oliver Schub; Kevin Breitkreuz; Danielle Dewar; Ivan Rupes; Brenda Andrews; Mike Tyers
CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast.
Cell 2004;117(7):899-913.
2004: Tim Hughes; Brenda Andrews; Charles Boone
Old drugs, new tricks: using genetically sensitized yeast to reveal drug targets.
Cell 2004;116(1):5-7.
2004: Jason Moffat; Brenda Andrews
Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast.
Nature cell biology 2004;6(1):59-66.
2003: Jason Moffat; Brenda Andrews
Ac'septin' a signal: kinase regulation by septins.
Developmental cell 2003;5(4):528-30.
2003: Helena Friesen; Kelly Murphy; Ashton Breitkreutz; Mike Tyers; Brenda Andrews
Regulation of the yeast amphiphysin homologue Rvs167p by phosphorylation.
Molecular biology of the cell 2003;14(7):3027-40.
2003: Michael Costanzo; Oliver Schub; Brenda Andrews
G1 transcription factors are differentially regulated in Saccharomyces cerevisiae by the Swi6-binding protein Stb1.
Molecular and cellular biology 2003;23(14):5064-77.
2003: Paul Jorgensen; Bobby-Joe Breitkreutz; K Breitkreutz; Chris Stark; G Liu; M Cook; Jeffrey R Sharom; Joy L Nishikawa; Troy Ketela; David S Bellows; Ashton Breitkreutz; Ivan Rupes; Lorrie Boucher; D Dewar; M Vo; M Angeli; Teresa Reguly; A Tong; Brenda Andrews; Charles Boone; Mike Tyers
Harvesting the genome's bounty: integrative genomics.
Cold Spring Harbor symposia on quantitative biology 2003;68():431-43.
2002: Paul Jorgensen; Bryce Nelson; Mark D Robinson; Yiqun Chen; Brenda Andrews; Mike Tyers; Charles Boone
High-resolution genetic mapping with ordered arrays of Saccharomyces cerevisiae deletion mutants.
Genetics 2002;162(3):1091-9.
2002: Dongqing Huang; Jason Moffat; Brenda Andrews
Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity.
Molecular and cellular biology 2002;22(14):5076-88.
2001: Amy Hin Yan Tong; Marie Evangelista; Ainslie B Parsons; H Xu; Gary Bader; Nicolas Pagé; M Robinson; S Raghibizadeh; Christopher W V Hogue; Howard Bussey; Brenda Andrews; Mike Tyers; Charles Boone
Systematic genetic analysis with ordered arrays of yeast deletion mutants.
Science (New York, N.Y.) 2001;294(5550):2364-8.
2001: HJ McBride; Alok Kumar Sil; Vivien Measday; Yaxin Yu; Jason Moffat; M E Maxon; I Herskowitz; Brenda Andrews; David J Stillman
The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae.
Molecular microbiology 2001;42(2):345-53.
2001: Kristin Baetz; Jason Moffat; Jennifer Haynes; M Chang; Brenda Andrews
Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4.
Molecular and cellular biology 2001;21(19):6515-28.
2000: Neil Macpherson; Vivien Measday; L Moore; Brenda Andrews
A yeast taf17 mutant requires the Swi6 transcriptional activator for viability and shows defects in cell cycle-regulated transcription.
Genetics 2000;154(4):1561-76.
2000: Vivien Measday; HJ McBride; Jason Moffat; David J Stillman; Brenda Andrews
Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast.
Molecular microbiology 2000;35(4):825-34.
1999: D Huang; G Patrick; Jason Moffat; Li-Huei Tsai; Brenda Andrews
Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14445-50.
1999: Kristin Baetz; Brenda Andrews
Regulation of cell cycle transcription factor Swi4 through auto-inhibition of DNA binding.
Molecular and cellular biology 1999;19(10):6729-41.
1999: Karen Colwill; D Field; L Moore; James D Friesen; Brenda Andrews
In vivo analysis of the domains of yeast Rvs167p suggests Rvs167p function is mediated through multiple protein interactions.
Genetics 1999;152(3):881-93.
1998: J Lee; Karen Colwill; V Aneliunas; C Tennyson; L Moore; Yuen Ho; Brenda Andrews
Interaction of yeast Rvs167 and Pho85 cyclin-dependent kinase complexes may link the cell cycle to the actin cytoskeleton.
Current biology : CB 1998;8(24):1310-21.
1998: Brenda Andrews; Vivien Measday
The cyclin family of budding yeast: abundant use of a good idea.
Trends in genetics : TIG 1998;14(2):66-72.
1997: Jacques Archambault; R S Chambers; Michael S Kobor; Y Ho; Mireille Cartier; D Bolotin; Brenda Andrews; Caroline M Kane; Jack Greenblatt
An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14300-5.
1997: K Madden; YJ Sheu; Kristin Baetz; Brenda Andrews; Michael Snyder
SBF cell cycle regulator as a target of the yeast PKC-MAP kinase pathway.
Science (New York, N.Y.) 1997;275(5307):1781-4.
1997: Vivien Measday; L Moore; Ravi Retnakaran; J Lee; M Donoviel; A M Neiman; Brenda Andrews
A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase.
Molecular and cellular biology 1997;17(3):1212-23.
1997: Y Ho; S Mason; Ryuji Kobayashi; M Hoekstra; Brenda Andrews
Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):581-6.
1996: Karen Colwill; Tony Pawson; Brenda Andrews; J Prasad; James L Manley; John C Bell; Peter Duncan
The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.
The EMBO journal 1996;15(2):265-75.
1994: Vivien Measday; L Moore; J Ogas; Mike Tyers; Brenda Andrews
The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast.
Science (New York, N.Y.) 1994;266(5189):1391-5.