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Maurizio Federico

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Germana Falcone; Maurizio Federico; Giovanna Floridia; Alessia Mazzola; Flavia Michelini; Luisa Minghetti; Antonio Musio; Maria G Biferi; Gianluca Bossi; Federica Censi; Marco Crescenzi
Cytogenetic analysis of human cells reveals specific patterns of DNA damage in replicative and oncogene-induced senescence.
Sandra Columba Cabezas; Maurizio Federico
Sequences within RNA coding for HIV-1 Gag p17 are efficiently targeted to exosomes.
Jung-Hyun Lee; Mathias G Lichtenheld; Kalle Saksela; Ursula Schlötzer-Schrehardt; Gerold Schuler; Sebastian Wittki; Reinhard Zeidler; Tanja Bräu; Jochen Dindorf; Florian S Dreyer; Maurizio Federico; Stefanie Gross; Thomas Harrer; Ian C D Johnston; Kirsten Krätzel; Elisabeth Kremmer; Andreas S Baur
HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.

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All Publications

2013: Germana Falcone; Maurizio Federico; Giovanna Floridia; Alessia Mazzola; Flavia Michelini; Luisa Minghetti; Antonio Musio; Maria G Biferi; Gianluca Bossi; Federica Censi; Marco Crescenzi
Cytogenetic analysis of human cells reveals specific patterns of DNA damage in replicative and oncogene-induced senescence.
Aging cell 2013;12(2):312-5.
2013: Sandra Columba Cabezas; Maurizio Federico
Sequences within RNA coding for HIV-1 Gag p17 are efficiently targeted to exosomes.
Cellular microbiology 2013;15(3):412-29.
2013: Jung-Hyun Lee; Mathias G Lichtenheld; Kalle Saksela; Ursula Schlötzer-Schrehardt; Gerold Schuler; Sebastian Wittki; Reinhard Zeidler; Tanja Bräu; Jochen Dindorf; Florian S Dreyer; Maurizio Federico; Stefanie Gross; Thomas Harrer; Ian C D Johnston; Kirsten Krätzel; Elisabeth Kremmer; Andreas S Baur
HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.
Molecular cell 2013;49(4):668-79.
2012: Laura Lattanzi; Maurizio Federico
A strategy of antigen incorporation into exosomes: comparing cross-presentation levels of antigens delivered by engineered exosomes and by lentiviral virus-like particles.
Vaccine 2012;30(50):7229-37.
2011: Eliana Ruggiero; Elena Toschi; Maurizio Federico
The activity of matrix metalloproteinase-9 is part of the mechanism of cell-to-cell HIV-1 endocytosis in dendritic cells.
Current drug discovery technologies 2011;8(2):112-8.
2011: A Sistigu; Laura Bracci; M Valentini; Enrico Proietti; Roberta Bona; Donatella R M Negri; Anna Rita Ciccaglione; Elena Tritarelli; Roberto Nisini; Michele Equestre; Angela Costantino; Cinzia Marcantonio; Stefano M Santini; Caterina Lapenta; Serena Donati; P Tataseo; M Miceli; Andrea Cara; Maurizio Federico
Strong CD8+ T cell antigenicity and immunogenicity of large foreign proteins incorporated in HIV-1 VLPs able to induce a Nef-dependent activation/maturation of dendritic cells.
Vaccine 2011;29(18):3465-75.
2010: Claudia Muratori; Giorgio Mangino; Elisabetta Affabris; Maurizio Federico
Astrocytes contacting HIV-1-infected macrophages increase the release of CCL2 in response to the HIV-1-dependent enhancement of membrane-associated TNFα in macrophages.
Glia 2010;58(16):1893-904.
2010: Claudia Muratori; Roberta Bona; Maurizio Federico
Lentivirus-based virus-like particles as a new protein delivery tool.
Methods in molecular biology (Clifton, N.J.) 2010;614():111-24.
2009: Paola Di Bonito; Felicia Grasso; Stefania Mochi; Linda Petrone; Emanuele Fanales-Belasio; Arianna Mei; Armando Cesolini; Giuseppe Laconi; Heinke Conrad; Helga Bernhard; Claudia J Dembek; Antonio Cosma; Stefano M Santini; Caterina Lapenta; Serena Donati; Claudia Muratori; Colomba Giorgi; Maurizio Federico
Anti-tumor CD8+ T cell immunity elicited by HIV-1-based virus-like particles incorporating HPV-16 E7 protein.
Virology 2009;395(1):45-55.
2009: Claudia Muratori; Eliana Ruggiero; Antonella Sistigu; Roberta Bona; Maurizio Federico
Human immunodeficiency virus type 1 (HIV-1) protease inhibitors block cell-to-cell HIV-1 endocytosis in dendritic cells.
The Journal of general virology 2009;90(Pt 11):2777-87.
2009: Claudia Muratori; Lucas E Cavallin; Kirsten Krätzel; Antonella Tinari; Angelo De Milito; Stefano Fais; Paola D'Aloja; Maurizio Federico; Vincenzo Vullo; Alla F Fomina; Enrique Mesri; Fabiana Superti; Andreas S Baur
Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells.
Cell host & microbe 2009;6(3):218-30.
2009: Eleonora Olivetta; Cinzia Mallozzi; Vitalba Ruggieri; Donatella Pietraforte; Maurizio Federico; Massimo Sanchez
HIV-1 Nef induces p47(phox) phosphorylation leading to a rapid superoxide anion release from the U937 human monoblastic cell line.
Journal of cellular biochemistry 2009;106(5):812-22.
2009: Claudia Muratori; Roberta Bona; Eliana Ruggiero; Gabriella D'Ettorre; Vincenzo Vullo; Mauro Andreotti; Maurizio Federico
DC contact with HIV-1-infected cells leads to high levels of Env-mediated virion endocytosis coupled with enhanced HIV-1 Ag presentation.
European journal of immunology 2009;39(2):404-16.
2008: Eliana Ruggiero; Roberta Bona; Claudia Muratori; Maurizio Federico
Virological consequences of early events following cell-cell contact between human immunodeficiency virus type 1-infected and uninfected CD4+ cells.
Journal of virology 2008;82(16):7773-89.
2007: Claudia Muratori; Antonella Sistigu; Eliana Ruggiero; Mario Falchi; Ilaria Bacigalupo; Clelia Palladino; Elena Toschi; Maurizio Federico
Macrophages transmit human immunodeficiency virus type 1 products to CD4-negative cells: involvement of matrix metalloproteinase 9.
Journal of virology 2007;81(17):9078-87.
2007: Gianna Fiorucci; Eleonora Olivetta; Maria V Chiantore; Maurizio Federico
Microarray analysis reveals CCL24/eotaxin-2 as an effector of the pathogenetic effects induced by HIV-1 Nef.
Current drug discovery technologies 2007;4(1):12-23.
2007: Giorgio Mangino; Zulema A Percario; Gianna Fiorucci; Gabriele Vaccari; Santiago Manrique; Giovanna Romeo; Maurizio Federico; Matthias Geyer; Elisabetta Affabris
In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the release of beta interferon.
Journal of virology 2007;81(6):2777-91.
2006: Eleonora Olivetta; Maurizio Federico
HIV-1 Nef protects human-monocyte-derived macrophages from HIV-1-induced apoptosis.
Experimental cell research 2006;312(6):890-900.
2006: Silvia Peretti; Ilaria Schiavoni; Katherina Pugliese; Maurizio Federico
Selective elimination of HIV-1-infected cells by Env-directed, HIV-1-based virus-like particles.
Virology 2006;345(1):115-26.
2006: Claudia Muratori; Paola D'Aloja; Fabiana Superti; Antonella Tinari; Nathalie Sol-Foulon; Sandra Sparacio; Valerie Bosch; Olivier Schwartz; Maurizio Federico
Generation and characterization of a stable cell population releasing fluorescent HIV-1-based Virus Like Particles in an inducible way.
BMC biotechnology 2006;6():52.
2005: Silvia Peretti; Ilaria Schiavoni; Katherina Pugliese; Maurizio Federico
Cell death induced by the herpes simplex virus-1 thymidine kinase delivered by human immunodeficiency virus-1-based virus-like particles.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):1185-96.
2005: Eleonora Olivetta; Donatella Pietraforte; Ilaria Schiavoni; Maurizio Minetti; Maurizio Federico; Massimo Sanchez
HIV-1 Nef regulates the release of superoxide anions from human macrophages.
The Biochemical journal 2005;390(Pt 2):591-602.
2004: Maurizio Federico
Targeting the Nef induced increase of HIV infectivity.
Current drug targets. Immune, endocrine and metabolic disorders 2004;4(4):321-6.
2004: Ilaria Schiavoni; Susanna Trapp; Anna Claudia Santarcangelo; Valentina Piacentini; Katherina Pugliese; Andreas S Baur; Maurizio Federico
HIV-1 Nef enhances both membrane expression and virion incorporation of Env products. A model for the Nef-dependent increase of HIV-1 infectivity.
The Journal of biological chemistry 2004;279(22):22996-3006.
2004: Ilaria Schiavoni; Claudia Muratori; V Piacentini; Anna Maria Giammarioli; Maurizio Federico
The HIV-1 Nef protein: how an AIDS pathogenetic factor turns to a tool for combating AIDS.
Current drug targets. Immune, endocrine and metabolic disorders 2004;4(1):19-27.
2003: Zulema A Percario; Eleonora Olivetta; Gianna Fiorucci; Giorgio Mangino; Silvia Peretti; Giovanna Romeo; Elisabetta Affabris; Maurizio Federico
Human immunodeficiency virus type 1 (HIV-1) Nef activates STAT3 in primary human monocyte/macrophages through the release of soluble factors: involvement of Nef domains interacting with the cell endocytotic machinery.
Journal of leukocyte biology 2003;74(5):821-32.
2003: Eleonora Olivetta; Zulema A Percario; Gianna Fiorucci; Gianfranco Mattia; Ilaria Schiavoni; Caitriona Dennis; Joachim Jäger; Mark Harris; Giovanna Romeo; Elisabetta Affabris; Maurizio Federico
HIV-1 Nef induces the release of inflammatory factors from human monocyte/macrophages: involvement of Nef endocytotic signals and NF-kappa B activation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1716-27.
2003: Maurizio Federico
From lentiviruses to lentivirus vectors.
Methods in molecular biology (Clifton, N.J.) 2003;229():3-15.
2002: Claudia Muratori; Ilaria Schiavoni; Gianna Melucci-Vigo; Eleonora Olivetta; Anna Claudia Santarcangelo; Katherina Pugliese; Paola Verani; Maurizio Federico
Inducible expression of the deltaNGFr/F12Nef fusion protein as a new tool for anti-human immunodeficiency virus type 1 gene therapy.
Human gene therapy 2002;13(14):1751-66.
2001: Maurizio Federico; Zulema A Percario; Eleonora Olivetta; Gianna Fiorucci; Claudia Muratori; A Micheli; Giovanna Romeo; Elisabetta Affabris
HIV-1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors.
Blood 2001;98(9):2752-61.
2001: Paola D'Aloja; Anna Claudia Santarcangelo; S Arold; Andreas S Baur; Maurizio Federico
Genetic and functional analysis of the human immunodeficiency virus (HIV) type 1-inhibiting F12-HIVnef allele.
The Journal of general virology 2001;82(Pt 11):2735-45.
2001: Oliver T Fackler; Paola D'Aloja; Andreas S Baur; Maurizio Federico; B Matija Peterlin
Nef from human immunodeficiency virus type 1(F12) inhibits viral production and infectivity.
Journal of virology 2001;75(14):6601-8.
2000: L Alessandrini; Anna Claudia Santarcangelo; Eleonora Olivetta; Flavia Ferrantelli; Paola D'Aloja; Katherina Pugliese; Elvira Pelosi; Cristiana Chelucci; Gianfranco Mattia; Cesare Peschle; Paola Verani; Maurizio Federico
T-tropic human immunodeficiency virus (HIV) type 1 Nef protein enters human monocyte-macrophages and induces resistance to HIV replication: a possible mechanism of HIV T-tropic emergence in AIDS.
The Journal of general virology 2000;81(Pt 12):2905-17.
2000: Lucia Conti; Barbara Varano; Maria Cristina Gauzzi; Paola Matarrese; Maurizio Federico; Walter Malorni; Filippo Belardelli; Sandra Gessani
Impairment of human immunodeficiency virus type 1 (HIV-1) entry into Jurkat T cells by constitutive expression of the HIV-1 vpr protein: role of CD4 down-modulation.
Journal of virology 2000;74(21):10207-11.
2000: Eleonora Olivetta; Katherina Pugliese; Roberta Bona; Paola D'Aloja; Flavia Ferrantelli; Anna Claudia Santarcangelo; Gianfranco Mattia; Paola Verani; Maurizio Federico
cis expression of the F12 human immunodeficiency virus (HIV) Nef allele transforms the highly productive NL4-3 HIV type 1 to a replication-defective strain: involvement of both Env gp41 and CD4 intracytoplasmic tails.
Journal of virology 2000;74(1):483-92.
1999: Maurizio Federico
Lentiviruses as gene delivery vectors.
Current opinion in biotechnology 1999;10(5):448-53.
1999: Cristiana Chelucci; Ida Casella; Maurizio Federico; Ugo Testa; Giampiero Macioce; Elvira Pelosi; Raffaella Guerriero; Gualtiero Mariani; Adele Giampaolo; Hamisa J Hassan; Cesare Peschle
Lineage-specific expression of human immunodeficiency virus (HIV) receptor/coreceptors in differentiating hematopoietic precursors: correlation with susceptibility to T- and M-tropic HIV and chemokine-mediated HIV resistance.
Blood 1999;94(5):1590-600.
1998: Paola D'Aloja; Eleonora Olivetta; Roberta Bona; Filomena Nappi; D Pedacchia; Katherina Pugliese; G Ferrari; Paola Verani; Maurizio Federico
gag, vif, and nef genes contribute to the homologous viral interference induced by a nonproducer human immunodeficiency virus type 1 (HIV-1) variant: identification of novel HIV-1-inhibiting viral protein mutants.
Journal of virology 1998;72(5):4308-19.
1998: Cristiana Chelucci; Maurizio Federico; Raffaella Guerriero; Gianfranco Mattia; Ida Casella; Elvira Pelosi; Ugo Testa; Gualtiero Mariani; Hamisa J Hassan; Cesare Peschle
Productive human immunodeficiency virus-1 infection of purified megakaryocytic progenitors/precursors and maturing megakaryocytes.
Blood 1998;91(4):1225-34.
1997: Roberta Bona; Paola D'Aloja; Eleonora Olivetta; Andrea Modesti; Anna Modica; Andrea Geraci; G Ferrari; Paola Verani; Maurizio Federico
Aberrant, noninfectious HIV-1 particles are released by chronically infected human T cells transduced with a retroviral vector expressing an interfering HIV-1 variant.
Gene therapy 1997;4(10):1085-92.
1997: M Baiocchi; Eleonora Olivetta; Cristiana Chelucci; Anna Claudia Santarcangelo; Roberta Bona; Paola D'Aloja; Ugo Testa; N Komatsu; Paola Verani; Maurizio Federico
Human immunodeficiency virus (HIV)-resistant CD4+ UT-7 megakaryocytic human cell line becomes highly HIV-1 and HIV-2 susceptible upon CXCR4 transfection: induction of cell differentiation by HIV-1 infection.
Blood 1997;89(8):2670-8.
1996: F Carlini; A Nicolini; Paola D'Aloja; Maurizio Federico; Paola Verani
The non-producer phenotype of the human immunodeficiency virus type 1 provirus F12/HIV-1 is the result of multiple genetic variations.
The Journal of general virology 1996;77 ( Pt 9)():2009-13.
1996: Maurizio Federico; Filomena Nappi; F Mavilio; Paola Verani
A replication-deficient human immunodeficiency virus-1 genome as an interference-inducing provirus.
Antibiotics and chemotherapy 1996;48():217-25.
1996: Maurizio Federico; Roberta Bona; Paola D'Aloja; M Baiocchi; K Pugliese; Filomena Nappi; Cristiana Chelucci; F Mavilio; Paola Verani
Anti-HIV viral interference induced by retroviral vectors expressing a nonproducer HIV-1 variant.
Acta haematologica 1996;95(3-4):199-203.
1995: Maurizio Federico; Filomena Nappi; G Ferrari; Cristiana Chelucci; F Mavilio; Paola Verani
A nonproducer, interfering human immunodeficiency virus (HIV) type 1 provirus can be transduced through a murine leukemia virus-based retroviral vector: recovery of an anti-HIV mouse/human pseudotype retrovirus.
Journal of virology 1995;69(11):6618-26.
1995: Cristiana Chelucci; Hamisa J Hassan; C Locardi; D Bulgarini; Elvira Pelosi; Gualtiero Mariani; Ugo Testa; Maurizio Federico; Mauro Valtieri; Cesare Peschle
In vitro human immunodeficiency virus-1 infection of purified hematopoietic progenitors in single-cell culture.
Blood 1995;85(5):1181-7.
1995: Maurizio Federico; Filomena Nappi; Roberta Bona; Paola D'Aloja; Paola Verani; G B Rossi
Full expression of transfected nonproducer interfering HIV-1 proviral DNA abrogates susceptibility of human He-La CD4+ cells to HIV.
Virology 1995;206(1):76-84.
1993: Maurizio Federico; B Taddeo; F Carlini; Filomena Nappi; Paola Verani; G B Rossi
A recombinant retrovirus carrying a non-producer human immunodeficiency virus (HIV) type 1 variant induces resistance to superinfecting HIV.
The Journal of general virology 1993;74 ( Pt 10)():2099-110.
1993: B Taddeo; Maurizio Federico; Fausto Titti; G B Rossi; Paola Verani
Homologous superinfection of both producer and nonproducer HIV-infected cells is blocked at a late retrotranscription step.
Virology 1993;194(2):441-52.
1993: Maurizio Federico; B Taddeo; Filomena Nappi; A Nicolini; G B Rossi; Paola Verani
Transfection of a retroviral construct carrying a non producer HIV-1 variant induces HIV-1 resistance in CD4+ CEMss cells.
Journal of biological regulators and homeostatic agents 1993;7(2):41-9.
1993: Paola Verani; Stefano Buttò; B Taddeo; Maurizio Federico; G B Rossi
HIV variability and perspectives for a vaccine.
Vaccine 1993;11(5):542-4.
1992: Fausto Titti; Alessandra Borsetti; Maurizio Federico; Ugo Testa; ettore meccia; Paola Samoggia; Cesare Peschle; Paola Verani; G B Rossi
Extrachromosomal human immunodeficiency virus type 1 DNA forms in fresh peripheral blood lymphocytes and in two interleukin-2-independent T cell lines derived from peripheral blood lymphocytes of an asymptomatic seropositive subject.
The Journal of general virology 1992;73 ( Pt 12)():3087-97.
1991: Anna Maria Luciani; Antonella Rosi; Maria Teresa Maggiorella; Maurizio Federico; N Sulli; Paola Verani; G B Rossi; Vincenza Viti; Laura Guidoni
Interaction of HIV-1 with susceptible lymphoblastoid cells. 1H NMR studies.
FEBS letters 1991;285(1):11-6.
1991: Maurizio Federico; Maria Teresa Maggiorella; N Sulli; Laura Guidoni; Anna Maria Luciani; Antonella Rosi; Vincenza Viti; G B Rossi; Paola Verani
Metabolic and structural effects of HIV infection in human peripheral blood mononuclear cells can be monitored with 1H NMR spectroscopy.
Journal of acquired immune deficiency syndromes 1991;4(11):1073-81.
1989: Maurizio Federico; Fausto Titti; S Buttó; A Orecchia; F Carlini; B Taddeo; Beatrice Macchi; N Maggiano; Paola Verani; G B Rossi
Biologic and molecular characterization of producer and nonproducer clones from HUT-78 cells infected with a patient HIV isolate.
AIDS research and human retroviruses 1989;5(4):385-96.
1988: Eliana M Coccia; Maurizio Federico; Giovanna Romeo; Elisabetta Affabris; F Cofano; G B Rossi
Interferons-alpha/beta- and -gamma-resistant Friend cell variants exhibiting receptor sites for interferons but no induction of 2-5A synthetase and 67K protein kinase.
Journal of interferon research 1988;8(1):113-27.
1987: Elisabetta Affabris; Giovanna Romeo; Maurizio Federico; Eliana M Coccia; C Locardi; Filippo Belardelli; G B Rossi
Molecular mechanisms of action of interferons in the Friend virus-induced leukemia cell system.
Haematologica 1987;72(6 Suppl):76-8.
1987: C Locardi; Filippo Belardelli; Maurizio Federico; Giovanna Romeo; Elisabetta Affabris; I Gresser
Effect of mouse interferon alpha/beta on the expression of H-2 (class I) antigens and on the levels of 2'-5' oligoadenylate synthetase activity in interferon-sensitive and interferon-resistant Friend leukemia cell tumors in mice.
Journal of biological regulators and homeostatic agents 1987;1(4):189-94.
1987: G B Rossi; Paola Verani; Beatrice Macchi; Maurizio Federico; A Orecchia; Loredana Nicoletti; Stefano Buttò; Adriano Lazzarin; G Mariani; G Ippolito
Recovery of HIV-related retroviruses from Italian patients with AIDS or AIDS-related complex and from asymptomatic at-risk individuals.
Annals of the New York Academy of Sciences 1987;511():390-400.