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Richard Fedorak

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Julia J Liu; Yuefei Lou; Karen L Madsen; Daniel Muruve; Jan K Rudzinski; Consolato Sergi; Aducio L Thiesen; Eytan Wine; Misagh Alipour; Pierre Boulanger; Elisabeth M Davis; Richard N Fedorak; Randall T Irvin
Epithelial cell extrusion leads to breaches in the intestinal epithelium.
Jean-Francois Turcotte; Stephanie J Mah; John R Saltzman; Brian Claggett; Richard N Fedorak; Dina Kao; Julia J Liu
Breaks in the wall: increased gaps in the intestinal epithelium of irritable bowel syndrome patients identified by confocal laser endomicroscopy (with videos).
Natasha S Stephens; Xiaorong Su; Richard N Fedorak; Travis B Murdoch; Jesse Siffledeen; Carolyn Slupsky
Urinary NMR metabolomic profiles discriminate inflammatory bowel disease from healthy.

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2013: Julia J Liu; Yuefei Lou; Karen L Madsen; Daniel Muruve; Jan K Rudzinski; Consolato Sergi; Aducio L Thiesen; Eytan Wine; Misagh Alipour; Pierre Boulanger; Elisabeth M Davis; Richard N Fedorak; Randall T Irvin
Epithelial cell extrusion leads to breaches in the intestinal epithelium.
Inflammatory bowel diseases 2013;19(5):912-21.
2013: Jean-Francois Turcotte; Stephanie J Mah; John R Saltzman; Brian Claggett; Richard N Fedorak; Dina Kao; Julia J Liu
Breaks in the wall: increased gaps in the intestinal epithelium of irritable bowel syndrome patients identified by confocal laser endomicroscopy (with videos).
Gastrointestinal endoscopy 2013;77(4):624-30.
2013: Natasha S Stephens; Xiaorong Su; Richard N Fedorak; Travis B Murdoch; Jesse Siffledeen; Carolyn Slupsky
Urinary NMR metabolomic profiles discriminate inflammatory bowel disease from healthy.
Journal of Crohn's & colitis 2013;7(2):e42-8.
2013: Sanam Verma; Karen I Kroeker; Richard N Fedorak
Adalimumab for orbital myositis in a patient with Crohn's disease who discontinued infliximab: a case report and review of the literature.
BMC gastroenterology 2013;13():59.
2012: Anna M Borowiec; Thomas A Churchill; Jason Doyle; Le Luo Guan; Karen Madsen; Beate C Sydora; Richard N Fedorak
Small bowel fibrosis and systemic inflammatory response after ileocolonic anastomosis in IL-10 null mice.
The Journal of surgical research 2012;178(1):147-54.
2012: Cathy Lu; Kata Matic; Mario Millan; Daniel C Sadowski; Christopher W Teshima; Dennis Todoruk; Alistair Waugh; Clarence Wong; Karen Wong; Robert J Bailey; Raeleen Cherry; Levinus A Dieleman; Leah Gramlich; Karen I Kroeker; Richard N Fedorak
Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation.
World journal of gastroenterology : WJG 2012;18(36):5058-64.
2012: Isaac Soo; Bob McQueen; Jesse Siffledeen; Kerry Siminoski; Richard N Fedorak
Risedronate improves bone mineral density in Crohn's disease: a two year randomized controlled clinical trial.
Journal of Crohn's & colitis 2012;6(7):777-86.
2012: Thomas W Lee; Richard N Fedorak; Michael R Kolber; Sander Veldhuyzen van Zanten
Iron replacement therapy in inflammatory bowel disease patients with iron deficiency anemia: a systematic review and meta-analysis.
Journal of Crohn's & colitis 2012;6(3):267-75.
2012: Beate C Sydora; Rae R Foshaug; Eric J Albert; Thomas A Churchill; Jason S G Doyle; Richard N Fedorak
Intravenous injection of endogenous microbial components abrogates DSS-induced colitis.
Digestive diseases and sciences 2012;57(2):345-54.
2012: Jean-Francois Turcotte; Eytan Wine; Karen Wong; Stephanie J Mah; John R Saltzman; Brian Claggett; Levinus A Dieleman; Richard N Fedorak; Dina Kao; Karen Kroeker; Julia J Liu
Increased epithelial gaps in the small intestine are predictive of hospitalization and surgery in patients with inflammatory bowel disease.
Clinical and translational gastroenterology 2012;3():e19.
2012: Naomi S C Hotte; Saad Y Salim; Robert H Tso; John Walker; Eric J Albert; Phil Bach; Levinus A Dieleman; Richard N Fedorak; Karen L Madsen
Patients with inflammatory bowel disease exhibit dysregulated responses to microbial DNA.
PloS one 2012;7(5):e37932.
2011: Forough Sanaee; Alistair W G Waugh; John D Clements; Richard N Fedorak; Richard Lewanczuk; Fakhreddin Jamali
Drug-disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity.
British journal of clinical pharmacology 2011;72(5):787-97.
2011: T W Lee; R Singh; Richard N Fedorak
A one-hour infusion of infliximab during maintenance therapy is safe and well tolerated: a prospective cohort study.
Alimentary pharmacology & therapeutics 2011;34(2):181-7.
2011: Julia J Liu; Karen Wong; Aducio L Thiesen; Stephanie J Mah; Levinus A Dieleman; Brian Claggett; John R Saltzman; Richard N Fedorak
Increased epithelial gaps in the small intestines of patients with inflammatory bowel disease: density matters.
Gastrointestinal endoscopy 2011;73(6):1174-80.
2011: Beate C Sydora; Sarah M McFarlane; Jason S G Doyle; Richard N Fedorak
Neonatal exposure to fecal antigens reduces intestinal inflammation.
Inflammatory bowel diseases 2011;17(4):899-906.
2011: Julia J Liu; Karen L Madsen; Pierre Boulanger; Levinus A Dieleman; Jon Meddings; Richard N Fedorak
Mind the gaps: confocal endomicroscopy showed increased density of small bowel epithelial gaps in inflammatory bowel disease.
Journal of clinical gastroenterology 2011;45(3):240-5.
2011: Julia J Liu; Haiyu Bao; Pierre Boulanger; Richard N Fedorak; Stephanie J Mah; Stephen C Ogg; Jan K Rudzinski; Aducio L Thiesen; Eytan Wine; Karen L Madsen
Epithelial gaps in a rodent model of inflammatory bowel disease: a quantitative validation study.
Clinical and translational gastroenterology 2011;2():e3.
2011: Karen I Kroeker; Simon Lam; Iain Birchall; Richard N Fedorak
Patients with IBD are exposed to high levels of ionizing radiation through CT scan diagnostic imaging: a five-year study.
Journal of clinical gastroenterology 2011;45(1):34-9.
2010: Richard N Fedorak
Probiotics in the management of ulcerative colitis.
Gastroenterology & hepatology 2010;6(11):688-90.
2010: Richard N Fedorak; Karen Wong; Ron Bridges
Canadian Digestive Health Foundation Public Impact Series. Inflammatory bowel disease in Canada: Incidence, prevalence, and direct and indirect economic impact.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2010;24(11):651-5.
2010: A W G Waugh; S Garg; K Matic; Leah Gramlich; C Wong; Daniel C Sadowski; M Millan; R Bailey; D Todoruk; R Cherry; C W Teshima; Levinus A Dieleman; Richard N Fedorak
Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: long-term follow-up of a single centre cohort.
Alimentary pharmacology & therapeutics 2010;32(9):1129-34.
2010: Vadim Iablokov; Beate C Sydora; Rae Foshaug; Jon Meddings; DR Driedger; Thomas A Churchill; Richard N Fedorak
Naturally occurring glycoalkaloids in potatoes aggravate intestinal inflammation in two mouse models of inflammatory bowel disease.
Digestive diseases and sciences 2010;55(11):3078-85.
2010: Thomas W Lee; Richard N Fedorak
Tumor necrosis factor-α monoclonal antibodies in the treatment of inflammatory bowel disease: clinical practice pharmacology.
Gastroenterology clinics of North America 2010;39(3):543-57.
2010: Haili Wang; Victor K Tso; Carolyn Slupsky; Richard N Fedorak
Metabolomics and detection of colorectal cancer in humans: a systematic review.
Future oncology (London, England) 2010;6(9):1395-406.
2010: N Gies; K I Kroeker; K Wong; Richard N Fedorak
Treatment of ulcerative colitis with adalimumab or infliximab: long-term follow-up of a single-centre cohort.
Alimentary pharmacology & therapeutics 2010;32(4):522-8.
2010: William J Sandborn; Maria Abreu; Geert D'Haens; Jean-Frédéric Colombel; Severine Vermeire; Krassimir Mitchev; Corinne Jamoul; Richard N Fedorak; Martina E Spehlmann; Douglas C Wolf; Scott Lee; Paul Rutgeerts
Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2010;8(8):688-695.e2.
2010: Beate C Sydora; S M MacFarlane; Maryla Lupicki; A L Dmytrash; Levinus A Dieleman; Richard N Fedorak
An imbalance in mucosal cytokine profile causes transient intestinal inflammation following an animal's first exposure to faecal bacteria and antigens.
Clinical and experimental immunology 2010;161(1):187-96.
2010: Victoria Y L Ung; Rae R Foshaug; Sarah M MacFarlane; Thomas A Churchill; Jason S G Doyle; Beate C Sydora; Richard N Fedorak
Oral administration of curcumin emulsified in carboxymethyl cellulose has a potent anti-inflammatory effect in the IL-10 gene-deficient mouse model of IBD.
Digestive diseases and sciences 2010;55(5):1272-7.
2010: Justin Cheung; Andrea Yu; Joseph LaBossiere; Qiaohao Zhu; Richard N Fedorak
Peptic ulcer bleeding outcomes adversely affected by end-stage renal disease.
Gastrointestinal endoscopy 2010;71(1):44-9.
2009: Christopher W Teshima; Adrienne Thompson; LeRose Dhanoa; Levinus A Dieleman; Richard N Fedorak
Long-term response rates to infliximab therapy for Crohn's disease in an outpatient cohort.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2009;23(5):348-52.
2009: Hien Q Huynh; Jennifer deBruyn; Leluo Guan; Hugo Diaz; Meiju Li; Safwat Girgis; Justine Turner; Richard N Fedorak; Karen Madsen
Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: a pilot study.
Inflammatory bowel diseases 2009;15(5):760-8.
2009: Neeraj Narula; Richard N Fedorak
Does smoking reduce infliximab's effectiveness against Crohn's disease?
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2009;23(2):121-5.
2009: Vivek Dhawan; Ahmed Mohamed; Richard N Fedorak
Gastric intramural hematoma: a case report and literature review.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2009;23(1):19-22.
2008: Justin Cheung; Robert Bailey; Sander Veldhuyzen van Zanten; Ross McLean; Richard N Fedorak; John Morse; Mario Millan; Tom Guzowski; Karen J Goodman
Early experience with unsedated ultrathin 4.9 mm transnasal gastroscopy: a pilot study.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2008;22(11):917-22.
2008: Justin Cheung; Karen J Goodman; Rachel Munday; Karen Heavner; Janis Huntington; John Morse; Sander Veldhuyzen van Zanten; Richard N Fedorak; Andre Corriveau; Robert J Bailey
Helicobacter pylori infection in Canada's arctic: searching for the solutions.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2008;22(11):912-6.
2008: Christopher Teshima; Richard N Fedorak
Are there differences in type, dosage, and method of administration for the systemic steroids in IBD treatment?
Inflammatory bowel diseases 2008;14 Suppl 2():S216-8.
2008: William J Sandborn; Brian G Feagan; Richard N Fedorak; Ellen Scherl; Mark R Fleisher; Seymour Katz; Jewel Johanns; Marion Blank; Paul Rutgeerts
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease.
Gastroenterology 2008;135(4):1130-41.
2008: Richard N Fedorak
Understanding why probiotic therapies can be effective in treating IBD.
Journal of clinical gastroenterology 2008;42 Suppl 3 Pt 1():S111-5.
2008: Travis B Murdoch; Hao Fu; Sarah MacFarlane; Beate C Sydora; Richard N Fedorak; Carolyn Slupsky
Urinary metabolic profiles of inflammatory bowel disease in interleukin-10 gene-deficient mice.
Analytical chemistry 2008;80(14):5524-31.
2008: Richard N Fedorak; Levinus A Dieleman
Probiotics in the treatment of human inflammatory bowel diseases: update 2008.
Journal of clinical gastroenterology 2008;42 Suppl 2():S97-103.
2008: Martin H Floch; W Allan Walker; Stefano Guandalini; Patricia Hibberd; Sherwood Gorbach; Christina Surawicz; Mary Ellen Sanders; Guadalupe Garcia-Tsao; Eamonn M M Quigley; Erika Isolauri; Richard N Fedorak; Levinus A Dieleman
Recommendations for probiotic use--2008.
Journal of clinical gastroenterology 2008;42 Suppl 2():S104-8.
2008: Beate C Sydora; Sarah M MacFarlane; Michele M Tavernini; Jason S G Doyle; Richard N Fedorak
CD4+CD25+ regulatory T cells have divergent effects on intestinal inflammation in IL-10 gene-deficient mice.
Digestive diseases and sciences 2008;53(6):1544-52.
2008: Neeraj Narula; Richard N Fedorak
Exercise and inflammatory bowel disease.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2008;22(5):497-504.
2008: Joseph Romagnuolo; Robert Hilsden; Gurpal S Sandha; Marty Cole; Syd Bass; Gary May; Jonathan Love; Vincent G Bain; John McKaigney; Richard N Fedorak
Allopurinol to prevent pancreatitis after endoscopic retrograde cholangiopancreatography: a randomized placebo-controlled trial.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2008;6(4):465-71; quiz 371.
2008: Remo Panaccione; Richard N Fedorak; Guy Aumais; Edmond-Jean Bernard; C N Bernstein; Alain Bitton; Ken Croitoru; Levinus A Dieleman; Robert Enns; Brian G Feagan; D Franchimont; Gordon R Greenberg; Anne M Griffiths; John K Marshall; P Pare; S Patel; R Penner; C Render; Ernest Seidman; A Hillary Steinhart
Review and clinical perspectives for the use of infliximab in ulcerative colitis.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2008;22(3):261-72.
2008: I Soo; Karen L Madsen; Q Tejpar; Beate C Sydora; R Sherbaniuk; B Cinque; L Di Marzio; M Grazia Cifone; C Desimone; Richard N Fedorak
VSL#3 probiotic upregulates intestinal mucosal alkaline sphingomyelinase and reduces inflammation.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2008;22(3):237-42.
2008: Paul Rutgeerts; Stefan Schreiber; Brian Feagan; Dorothy L Keininger; Liz O'Neil; Richard N Fedorak
Certolizumab pegol, a monthly subcutaneously administered Fc-free anti-TNFalpha, improves health-related quality of life in patients with moderate to severe Crohn's disease.
International journal of colorectal disease 2008;23(3):289-96.
2008: Rachid Mohamed; Robert Schultz; Richard N Fedorak
Oropharyngeal Crohn's disease.
Clinical and experimental gastroenterology 2008;1():15-8.
2008: Vishal Anand; Anthony S Russell; Ross Tsuyuki; Richard N Fedorak
Perinuclear antineutrophil cytoplasmic autoantibodies and anti-Saccharomyces cerevisiae antibodies as serological markers are not specific in the identification of Crohn's disease and ulcerative colitis.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2008;22(1):33-6.
2008: Rodrigo Bibiloni; Puneeta Tandon; Florencia Vargas-Voracka; Raphael Barreto-Zuniga; Andres Lupian-Sanchez; MIGUEL ANGEL RICO HINOJOSA; Jennifer Guban; Richard N Fedorak; Gerald W Tannock
Differential clustering of bowel biopsy-associated bacterial profiles of specimens collected in Mexico and Canada: what do these profiles represent?
Journal of medical microbiology 2008;57(Pt 1):111-7.
2007: Anna M Borowiec; Richard N Fedorak
The role of probiotics in management of irritable bowel syndrome.
Current gastroenterology reports 2007;9(5):393-400.
2007: Beate C Sydora; Sarah M Macfarlane; John W Walker; Andrea L Dmytrash; Thomas A Churchill; Jason Doyle; Richard N Fedorak
Epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain IBD in the IL-10 gene-deficient mouse.
Inflammatory bowel diseases 2007;13(8):947-54.
2007: Constantine J Karvellas; Richard N Fedorak; John Hanson; Clarence K W Wong
Increased risk of colorectal cancer in ulcerative colitis patients diagnosed after 40 years of age.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2007;21(7):443-6.
2007: Jesse S Siffledeen; Kerry Siminoski; Ho Jen; Richard N Fedorak
Vertebral fractures and role of low bone mineral density in Crohn's disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007;5(6):721-8.
2007: Stephan R Targan; Brian G Feagan; Richard N Fedorak; Bret A Lashner; Remo Panaccione; Daniel H Present; Martina E Spehlmann; Paul J Rutgeerts; Zsolt Tulassay; Miroslava Volfova; Douglas C Wolf; Chito Hernandez; Jeffrey Bornstein; William J Sandborn
Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial.
Gastroenterology 2007;132(5):1672-83.
2007: Richard N Fedorak
Probiotic Therapies for IBD.
Gastroenterology & hepatology 2007;3(3):180-1.
2007: Cathy Alberda; Leah Gramlich; Jon Meddings; Catherine Field; Linda McCargar; Demetrios Kutsogiannis; Richard N Fedorak; Karen Madsen
Effects of probiotic therapy in critically ill patients: a randomized, double-blind, placebo-controlled trial.
The American journal of clinical nutrition 2007;85(3):816-23.
2006: Beate C Sydora; Michele M Tavernini; Jason Doyle; Richard N Fedorak
A defect in epithelial barrier integrity is not required for a systemic response to bacterial antigens or intestinal injury in T cell receptor-alpha gene-deficient mice.
Inflammatory bowel diseases 2006;12(8):750-7.
2006: Rodrigo Bibiloni; Marco Mangold; Karen L Madsen; Richard N Fedorak; Gerald W Tannock
The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients.
Journal of medical microbiology 2006;55(Pt 8):1141-9.
2006: Beate C Sydora; Sarah M Martin; Maryla Lupicki; Levinus A Dieleman; Jason Doyle; John W Walker; Richard N Fedorak
Bacterial antigens alone can influence intestinal barrier integrity, but live bacteria are required for initiation of intestinal inflammation and injury.
Inflammatory bowel diseases 2006;12(6):429-36.
2006: Kevin P Rioux; Richard N Fedorak
Probiotics in the treatment of inflammatory bowel disease.
Journal of clinical gastroenterology 2006;40(3):260-3.
2006: Stephen B Hanauer; William J Sandborn; Paul Rutgeerts; Richard N Fedorak; Milan Lukas; Donald MacIntosh; Remo Panaccione; Douglas Wolf; Paul F Pollack
Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial.
Gastroenterology 2006;130(2):323-33; quiz 591.
2005: Robert M Penner; Richard N Fedorak; Karen L Madsen
Probiotics and nutraceuticals: non-medicinal treatments of gastrointestinal diseases.
Current opinion in pharmacology 2005;5(6):596-603.
2005: Kevin P Rioux; Karen L Madsen; Richard N Fedorak
The role of enteric microflora in inflammatory bowel disease: human and animal studies with probiotics and prebiotics.
Gastroenterology clinics of North America 2005;34(3):465-82, ix.
2005: Robert M Penner; Karen L Madsen; Richard N Fedorak
Postoperative Crohn's disease.
Inflammatory bowel diseases 2005;11(8):765-77.
2005: Rodrigo Bibiloni; Richard N Fedorak; Gerald W Tannock; Karen L Madsen; Paolo Gionchetti; Massimo Campieri; Claudio De Simone; Ryan Sartor
VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis.
The American journal of gastroenterology 2005;100(7):1539-46.
2005: Brian G Feagan; Gordon R Greenberg; Gary Wild; Richard N Fedorak; Pierre Paré; J W D McDonald; Rejean Dubé; Albert Cohen; A Hillary Steinhart; Steven Landau; Rasha A Aguzzi; Irving H Fox; Margaret K Vandervoort
Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin.
The New England journal of medicine 2005;352(24):2499-507.
2005: Beate C Sydora; Michele M Tavernini; Jason S G Doyle; Richard N Fedorak
Association with selected bacteria does not cause enterocolitis in IL-10 gene-deficient mice despite a systemic immune response.
Digestive diseases and sciences 2005;50(5):905-13.
2005: Barbara M Waters; Louise Jensen; Richard N Fedorak
Effects of formal education for patients with inflammatory bowel disease: a randomized controlled trial.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2005;19(4):235-44.
2005: Farzana A Sayani; Connie Prosser; Robert J Bailey; Philip Jacobs; Richard N Fedorak
Thiopurine methyltransferase enzyme activity determination before treatment of inflammatory bowel disease with azathioprine: effect on cost and adverse events.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2005;19(3):147-51.
2005: Jesse S Siffledeen; Richard N Fedorak; Kerry Siminoski; Ho Jen; Eric Vaudan; Neena Abraham; Hillary Steinhart; Gordon Greenberg
Randomized trial of etidronate plus calcium and vitamin D for treatment of low bone mineral density in Crohn's disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(2):122-32.
2005: Richard N Fedorak; Lana Bistritz
Targeted delivery, safety, and efficacy of oral enteric-coated formulations of budesonide.
Advanced drug delivery reviews 2005;57(2):303-16.
2005: Robert M Penner; Richard N Fedorak
Probiotics in the management of inflammatory bowel disease.
MedGenMed : Medscape general medicine 2005;7(3):19.
2004: Remo Panaccione; Richard N Fedorak; Guy Aumais; Charles N Bernstein; Alain Bitton; Ken Croitoru; Robert Enns; Brian G Feagan; Marty Fishman; Gordon Greenberg; Anne Griffiths; John K Marshall; Imran Rasul; Daniel C Sadowski; Ernest Seidman; Hillary Steinhart; Lloyd Sutherland; Eric Walli; Gary Wild; C Noel Williams; Mary Zachos
Canadian Association of Gastroenterology Clinical Practice Guidelines: the use of infliximab in Crohn's disease.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2004;18(8):503-8.
2004: Alan Barkun; Sandrine Sabbah; Robert Enns; David Armstrong; Jamie Gregor; Richard N Fedorak; Elham Rahme; Youssef Toubouti; Myriam Martel; Naoki Chiba; Carlo A Fallone
The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting.
The American journal of gastroenterology 2004;99(7):1238-46.
2004: Richard N Fedorak; Karen L Madsen
Probiotics and the management of inflammatory bowel disease.
Inflammatory bowel diseases 2004;10(3):286-99.
2004: Jesse S Siffledeen; Richard N Fedorak; Kerry Siminoski; Ho Jen; Eric Vaudan; Neena Abraham; Hillary Seinhart; Gordon Greenberg
Bones and Crohn's: risk factors associated with low bone mineral density in patients with Crohn's disease.
Inflammatory bowel diseases 2004;10(3):220-8.
2004: Tarun Misra; Eoin Lalor; Richard N Fedorak
Endoscopic perforation rates at a Canadian university teaching hospital.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2004;18(4):221-6.
2004: Richard N Fedorak; Karen L Madsen
Probiotics and prebiotics in gastrointestinal disorders.
Current opinion in gastroenterology 2004;20(2):146-55.
2004: Richard N Fedorak
Is it time to re-classify Crohn's disease?
Best practice & research. Clinical gastroenterology 2004;18 Suppl():99-106.
2003: Sander Veldhuyzen van Zanten; Richard N Fedorak; Jean Lambert; Lawrence Cohen; Anita Vanjaka
Absence of symptomatic benefit of lansoprazole, clarithromycin, and amoxicillin triple therapy in eradication of Helicobacter pylori positive, functional (nonulcer) dyspepsia.
The American journal of gastroenterology 2003;98(9):1963-9.
2003: Jesse S Siffledeen; Kerry Siminoski; Hillary Steinhart; Gordon Greenberg; Richard N Fedorak
The frequency of vitamin D deficiency in adults with Crohn's disease.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2003;17(8):473-8.
2003: Beate C Sydora; Michele M Tavernini; Andreas Wessler; Laurence D Jewell; Richard N Fedorak
Lack of interleukin-10 leads to intestinal inflammation, independent of the time at which luminal microbial colonization occurs.
Inflammatory bowel diseases 2003;9(2):87-97.
2002: Karen L Madsen; Richard N Fedorak; Michele M Tavernini; Jason S G Doyle
Normal Breast Milk Limits the Development of Colitis in IL-10-Deficient Mice.
Inflammatory bowel diseases 2002;8(6):390-8.
2002: Bijal Patel; Robert Schutte; Peter Sporns; Jason Doyle; Lawrence Jewel; Richard N Fedorak
Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease.
Inflammatory bowel diseases 2002;8(5):340-6.
2002: Cliff Sample; Robert J Bailey; Dennis Todoruk; Daniel C Sadowski; Leah Gramlich; Mario Milan; Raeleen Cherry; Mang Ma; Eoin Lalor; John McKaigney; Richard Sherbaniuk; Kata Matic; Connie Switzer; Richard N Fedorak
Clinical experience with infliximab for Crohn's disease: the first 100 patients in Edmonton, Alberta.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2002;16(3):165-70.
2001: David L Sigalet; G M Lees; F X Aherne; Richard N Fedorak; Monika Keelan; Alan B R Thomson; John Van Aerde
Nutritional effects of surgical and medical treatment for short bowel syndrome.
JPEN. Journal of parenteral and enteral nutrition 2001;25(6):330-6.
2001: Joseph Romagnuolo; Richard N Fedorak; V C Dias; Fiona Bamforth; M Teltscher
Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study.
The American journal of gastroenterology 2001;96(7):2143-9.
2001: Richard N Fedorak
Canadian Association of Gastroenterology Clinical Practice Guidelines: the use of infliximab in Crohn's disease.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2001;15(6):367-70.
2001: Brian G Feagan; R Enns; Richard N Fedorak; Remo Panaccione; P Paré; A Hillary Steinhart; Gary Wild
Infliximab for the treatment of Crohn's disease: efficacy, safety and pharmacoeconomics.
The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 2001;8(4):188-98.
2000: Richard N Fedorak; A Gangl; Charles O Elson; Paul Rutgeerts; S Schreiber; Gary Wild; Stephen B Hanauer; A Kilian; M Cohard; LeBeaut Pierre Alexandre; Brian G Feagan
Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group.
Gastroenterology 2000;119(6):1473-82.
2000: S Schreiber; Richard N Fedorak; O H Nielsen; Gary Wild; C N Williams; S Nikolaus; M Jacyna; B A Lashner; A Gangl; Paul Rutgeerts; Kim L Isaacs; Sander J H van Deventer; J C Koningsberger; M Cohard; LeBeaut Pierre Alexandre; Stephen B Hanauer
Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study Group.
Gastroenterology 2000;119(6):1461-72.
2000: Karen L Madsen; Jason S G Doyle; Michele M Tavernini; Laurence D Jewell; Robert P Rennie; Richard N Fedorak
Antibiotic therapy attenuates colitis in interleukin 10 gene-deficient mice.
Gastroenterology 2000;118(6):1094-105.
2000: Brian G Feagan; Richard N Fedorak; E J Irvine; Gary Wild; Lloyd Sutherland; A Hillary Steinhart; Gordon R Greenberg; J Koval; C J Wong; M Hopkins; S B Hanauer; J W D McDonald
A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators.
The New England journal of medicine 2000;342(22):1627-32.
2000: Richard N Fedorak
Assessment of medical journal quality.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2000;14(2):89-90.
2000: Richard N Fedorak
Economic impact of digestive, nutritional and oral diseases in Canada.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2000;14(1):13-4.
1999: Karen L Madsen; D Malfair; D Gray; Jason S G Doyle; Laurence D Jewell; Richard N Fedorak
Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora.
Inflammatory bowel diseases 1999;5(4):262-70.
1999: William J Sandborn; William J Tremaine; D C Wolf; Stephan R Targan; C A Sninsky; L R Sutherland; Stephen B Hanauer; J W McDonald; Brian G Feagan; Richard N Fedorak; Kim L Isaacs; MG Pike; Dennis C Mays; James J Lipsky; S Gordon; CS Kleoudis; RH Murdock
Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease. North American Azathioprine Study Group.
Gastroenterology 1999;117(3):527-35.
1999: M M Pluhator-Murton; Richard N Fedorak; RJ Audette; Barbara J Marriage; Randall W Yatscoff; Leah Gramlich
Trace element contamination of total parenteral nutrition. 2. Effect of storage duration and temperature.
JPEN. Journal of parenteral and enteral nutrition 1999;23(4):228-32.
1999: M M Pluhator-Murton; Richard N Fedorak; RJ Audette; Barbara J Marriage; Randall W Yatscoff; Leah Gramlich
Trace element contamination of total parenteral nutrition. 1. Contribution of component solutions.
JPEN. Journal of parenteral and enteral nutrition 1999;23(4):222-7.
1999: Richard N Fedorak
1999 visiting research professorship and young investigator award.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1999;13(4):289-90.
1999: Karen L Madsen; Jason S G Doyle; Laurence D Jewell; Michele M Tavernini; Richard N Fedorak
Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice.
Gastroenterology 1999;116(5):1107-14.
1999: Richard N Fedorak
Growth of the Canadian Association of Gastroenterology: controlled, effective and impressive.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1999;13(3):191-3.
1999: Richard N Fedorak
An update and a revisit.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1999;13(2):105-6.
1998: Diane E Taylor; Q Jiang; Richard N Fedorak
Antibiotic susceptibilities of Helicobacter pylori strains isolated in the Province of Alberta.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1998;12(4):295-8.
1998: Karen L Madsen; Michele M Tavernini; Christine Yachimec; D L Mendrick; P J Alfonso; M Buergin; H S Olsen; M J Antonaccio; Alan B R Thomson; Richard N Fedorak
Stanniocalcin: a novel protein regulating calcium and phosphate transport across mammalian intestine.
The American journal of physiology 1998;274(1 Pt 1):G96-102.
1997: H W Nolen; Richard N Fedorak; D R Friend
Steady-state pharmacokinetics of corticosteroid delivery from glucuronide prodrugs in normal and colitic rats.
Biopharmaceutics & drug disposition 1997;18(8):681-95.
1997: Shaun A C Medlicott; Laurence D Jewell; L Price; Richard N Fedorak; R W Sherbaniuk; Stefan J Urbanski
Conservative management of small adenomata in ulcerative colitis.
The American journal of gastroenterology 1997;92(11):2094-8.
1997: Daniel C Sadowski; Malcolm C Champion; R Goeree; Desmond Leddin; N Otten; G Morris; I Beck; T Faloon; Richard N Fedorak
Health economics of gastroesophageal reflux disease.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1997;11 Suppl B():108B-112B.
1997: I T Beck; Malcolm C Champion; S Lemire; Alan B R Thomson; M Anvari; David Armstrong; Robert J Bailey; A N Barkun; M Boivin; Ford Bursey; H Chaun; N Chiba; A W Cockeram; J J Connon; L R Da Costa; T R Faloon; Richard N Fedorak; R R Gillies; Ron Goeree; Richard H Hunt; R I Inculet; A Klein; Desmond Leddin; J R Love; L J Worobetz
The Second Canadian Consensus Conference on the Management of Patients with Gastroesophageal Reflux Disease.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1997;11 Suppl B():7B-20B.
1997: Daniel C Sadowski; Richard N Fedorak; Robert J Bailey; Lesley Smith
Alberta Society of Gastroenterology consensus statement: Helicobacter pylori in peptic ulcer disease.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 1997;11(6):544-7.
1997: Karen L Madsen; S A Lewis; Michele M Tavernini; J Hibbard; Richard N Fedorak
Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion.
Gastroenterology 1997;113(1):151-9.
1997: Lloyd R Sutherland; F Martin; Robert J Bailey; Richard N Fedorak; M Poleski; C Dallaire; R Rossman; F Saibil; L Lariviere
A randomized, placebo-controlled, double-blind trial of mesalamine in the maintenance of remission of Crohn's disease. The Canadian Mesalamine for Remission of Crohn's Disease Study Group.
Gastroenterology 1997;112(4):1069-77.
1996: Karen L Madsen; D Ariano; Richard N Fedorak
Insulin downregulates diabetic-enhanced intestinal glucose transport rapidly in ileum and slowly in jejunum.
Canadian journal of physiology and pharmacology 1996;74(12):1294-301.
1996: M M Pluhator-Murton; Richard N Fedorak; RJ Audette; Barbara J Marriage; Randall W Yatscoff
Extent of trace-element contamination from simulated compounding of total parenteral nutrient solutions.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 1996;53(19):2299-303.
1996: Karen L Madsen; Michele M Tavernini; T R Mosmann; Richard N Fedorak
Interleukin 10 modulates ion transport in rat small intestine.
Gastroenterology 1996;111(4):936-44.
1996: N L Yanchar; Richard N Fedorak; Norman M Kneteman; D L Sigalet
Nutritional and intestinal effects of the novel immunosuppressive agents: deoxyspergualin, rapamycin, and mycophenolate mofetil.
Clinical biochemistry 1996;29(4):363-9.
1996: D L Sigalet; N N Kneteman; Richard N Fedorak; T Kizilisik; K E Madsen; A B Thomson
Small intestinal function following syngeneic transplantation in the rat.
The Journal of surgical research 1996;61(2):379-84.
1996: N L Yanchar; T M Riegel; G Martin; Richard N Fedorak; Norman M Kneteman; D L Sigalet
Tacrolimus (FK506)--its effects on intestinal glucose transport.
Transplantation 1996;61(4):630-4.
1996: N Cui; Karen L Madsen; D R Friend; Bruce R Stevenson; Richard N Fedorak
Increased permeability occurs in rat ileum following induction of pan-colitis.
Digestive diseases and sciences 1996;41(2):405-11.
1995: Richard N Fedorak; N Cui; D R Friend; Karen L Madsen; L R Empey
A novel colon-specific steroid prodrug enhances sodium chloride absorption in rat colitis.
The American journal of physiology 1995;269(2 Pt 1):G210-8.
1995: Karen L Madsen; N L Yanchar; D L Sigalet; T Reigel; Richard N Fedorak
FK506 increases permeability in rat intestine by inhibiting mitochondrial function.
Gastroenterology 1995;109(1):107-14.
1995: Richard N Fedorak; B Haeberlin; L R Empey; N Cui; H Nolen; Laurence D Jewell; D R Friend
Colonic delivery of dexamethasone from a prodrug accelerates healing of colitis in rats without adrenal suppression.
Gastroenterology 1995;108(6):1688-99.
1995: H Nolen; Richard N Fedorak; D R Friend
Budesonide-beta-D-glucuronide: a potential prodrug for treatment of ulcerative colitis.
Journal of pharmaceutical sciences 1995;84(6):677-81.
1995: M M Ma; E A Semlacher; Richard N Fedorak; E A Lalor; Donald R Duerksen; R W Sherbaniuk; C E Chalpelsky; Daniel C Sadowski
The buried gastrostomy bumper syndrome: prevention and endoscopic approaches to removal.
Gastrointestinal endoscopy 1995;41(5):505-8.
1995: Karen L Madsen; D Ariano; Richard N Fedorak
Vanadate treatment rapidly improves glucose transport and activates 6-phosphofructo-1-kinase in diabetic rat intestine.
Diabetologia 1995;38(4):403-12.
1995: B G Feagan; J Rochon; Richard N Fedorak; E Jan Irvine; G Wild; L Sutherland; A Hillary Steinhart; Gordon R Greenberg; R Gillies; M Hopkins
Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators.
The New England journal of medicine 1995;332(5):292-7.
1994: N Cui; D R Friend; Richard N Fedorak
A budesonide prodrug accelerates treatment of colitis in rats.
Gut 1994;35(10):1439-46.
1994: B G Feagan; J W McDonald; J Rochon; A Laupacis; Richard N Fedorak; D Kinnear; F Saibil; A Groll; A Archambault; R Gillies
Low-dose cyclosporine for the treatment of Crohn's disease. The Canadian Crohn's Relapse Prevention Trial Investigators.
The New England journal of medicine 1994;330(26):1846-51.
1994: Karen L Madsen; V M Porter; Richard N Fedorak
Vanadate reduces sodium-dependent glucose transport and increases glycolytic activity in LLC-PK1 epithelia.
Journal of cellular physiology 1994;158(3):459-66.
1994: E Jan Irvine; B Feagan; J Rochon; A Archambault; Richard N Fedorak; A Groll; D Kinnear; F Saibil; J W McDonald
Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Canadian Crohn's Relapse Prevention Trial Study Group.
Gastroenterology 1994;106(2):287-96.
1994: A D McLeod; Richard N Fedorak; D R Friend; T N Tozer; N Cui
A glucocorticoid prodrug facilitates normal mucosal function in rat colitis without adrenal suppression.
Gastroenterology 1994;106(2):405-13.
1993: Karen L Madsen; V M Porter; Richard N Fedorak
Oral vanadate reduces Na(+)-dependent glucose transport in rat small intestine.
Diabetes 1993;42(8):1126-32.
1993: W D Buie; O G Thurston; J E vanAerde; Frank Xavier Aherne; Alan B R Thomson; Richard N Fedorak
Jejunum is preferable for construction of a Bianchi bowel-lengthening procedure in swine short bowel.
Journal of pediatric surgery 1993;28(1):102-9.
1993: L R Empey; N Cui; Richard N Fedorak
Acetic acid-induced colitis results in bystander ileal injury.
Agents and actions 1993;38(1-2):76-84.
1992: Karen L Madsen; J B Meddings; Richard N Fedorak
Basolateral membrane lipid dynamics alter Na-K ATPase activity in rabbit small intestine.
Canadian journal of physiology and pharmacology 1992;70(11):1483-90.
1992: L R Empey; K Walker; Richard N Fedorak
Indomethacin worsens and a leukotriene biosynthesis inhibitor accelerates mucosal healing in rat colitis.
Canadian journal of physiology and pharmacology 1992;70(5):660-8.
1992: K J Torsher; L R Empey; Richard N Fedorak
Misoprostol therapy following trinitrobenzene sulfonic acid-induced colitis accelerates healing.
Prostaglandins, leukotrienes, and essential fatty acids 1992;45(4):275-81.
1992: Richard N Fedorak; L R Empey; K Walker
Verapamil alters eicosanoid synthesis and accelerates healing during experimental colitis in rats.
Gastroenterology 1992;102(4 Pt 1):1229-35.
1992: D L Sigalet; Norman M Kneteman; Richard N Fedorak; Aydin Tarik Kizilisik; Alan B R Thomson
Intestinal function following allogeneic small intestinal transplantation in the rat.
Transplantation 1992;53(2):264-71.
1992: L R Empey; J D Papp; Laurence D Jewell; Richard N Fedorak
Mucosal protective effects of vitamin E and misoprostol during acute radiation-induced enteritis in rats.
Digestive diseases and sciences 1992;37(2):205-14.
1992: J R Love; E Jan Irvine; Richard N Fedorak
Quality of life in inflammatory bowel disease.
Journal of clinical gastroenterology 1992;14(1):15-9.
1991: Richard N Fedorak; N Cortas; M Field
Diabetes mellitus and glucagon alter ouabain-sensitive Na(+)-K(+)-ATPase in rat small intestine.
Diabetes 1991;40(12):1603-10.
1991: Richard N Fedorak; Chris I Cheeseman; Alan B R Thomson; V M Porter
Altered glucose carrier expression: mechanism of intestinal adaptation during streptozocin-induced diabetes in rats.
The American journal of physiology 1991;261(4 Pt 1):G585-91.
1991: Richard N Fedorak; Alan B R Thomson; V M Porter
Adaptation of intestinal glucose transport in rats with diabetes mellitus occurs independent of hyperphagia.
Canadian journal of physiology and pharmacology 1991;69(8):1143-8.
1991: L R Empey; Laurence D Jewell; M L Garg; Alan B R Thomson; M Thomas Clandinin; Richard N Fedorak
Fish oil-enriched diet is mucosal protective against acetic acid-induced colitis in rats.
Canadian journal of physiology and pharmacology 1991;69(4):480-7.
1990: Alan B R Thomson; Monika Keelan; Ray V Rajotte; T Cheng; Richard N Fedorak; C Cheeseman; M Thomas Clandinin
Long-term effects of manipulations of dietary omega-3 fatty acids on clinical control and in vitro uptake of glucose and lipids in diabetic rats.
Diabetes research (Edinburgh, Scotland) 1990;15(2):85-93.
1990: D L Sigalet; G M Lees; Frank Xavier Aherne; John Van Aerde; Richard N Fedorak; Monika Keelan; Alan B R Thomson
The physiology of adaptation to small bowel resection in the pig: an integrated study of morphological and functional changes.
Journal of pediatric surgery 1990;25(6):650-7.
1990: Richard N Fedorak
Adaptation of small intestinal membrane transport processes during diabetes mellitus in rats.
Canadian journal of physiology and pharmacology 1990;68(5):630-5.
1990: Richard N Fedorak; L R Empey; C MacArthur; Laurence D Jewell
Misoprostol provides a colonic mucosal protective effect during acetic acid-induced colitis in rats.
Gastroenterology 1990;98(3):615-25.
1989: L R Empey; Richard N Fedorak
Effect of misoprostol in preventing stress-induced intestinal fluid secretion in rats.
Prostaglandins, leukotrienes, and essential fatty acids 1989;38(1):43-8.
1989: Richard N Fedorak; S L Allen
Effect of somatostatin analog (SMS 201-995) on in vivo intestinal fluid transport in rats. A limited systemic effect.
Digestive diseases and sciences 1989;34(4):567-72.
1989: Richard N Fedorak; A Kotake; F Douglas; E B Chang
Inhibition of cholera-toxin-stimulated intestinal secretion by CGS 9343B in rats: a specific calmodulin inhibitor.
Journal of pediatric gastroenterology and nutrition 1989;8(2):252-8.
1989: Richard N Fedorak; M D Gershon; M Field
Induction of intestinal glucose carriers in streptozocin-treated chronically diabetic rats.
Gastroenterology 1989;96(1):37-44.