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Robert Andrews

Research Profile

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

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Publications

TOP 3
Jianlin Qiao; Andrew W Roberts; Simone M Schoenwaelder; Huy Tran; Shaun P Jackson; Zane S Kaplan; Benjamin T Kile; Kylie D Mason; Robert K Andrews; Amanda K Davis; Elizabeth E Gardiner
Low adhesion receptor levels on circulating platelets in patients with lymphoproliferative diseases before receiving Navitoclax (ABT-263).
Elizabeth E Gardiner; Robert K Andrews
Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction.
Robert K Andrews
FoxO function PAR excellence...

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All Publications

2013: Jianlin Qiao; Andrew W Roberts; Simone M Schoenwaelder; Huy Tran; Shaun P Jackson; Zane S Kaplan; Benjamin T Kile; Kylie D Mason; Robert K Andrews; Amanda K Davis; Elizabeth E Gardiner
Low adhesion receptor levels on circulating platelets in patients with lymphoproliferative diseases before receiving Navitoclax (ABT-263).
Blood 2013;121(8):1479-81.
2012: Elizabeth E Gardiner; Robert K Andrews
Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction.
Blood reviews 2012;26(6):255-9.
2012: Robert K Andrews
FoxO function PAR excellence...
Thrombosis and haemostasis 2012;108(1):11.
2012: Jane F Arthur; Michael C Berndt; A K Davis; E Dunne; Elizabeth E Gardiner; J Qiao; Yang Shen; Robert K Andrews
ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways.
Journal of thrombosis and haemostasis : JTH 2012;10(6):1133-41.
2012: Mohammad Al-Tamimi; Robert K Andrews; Jane F Arthur; Michael C Berndt; Amanda K Davis; Justin R Hamilton; Shaun P Jackson; Ashkan Javadzadegan; Jing Jing; Leonard Kritharides; Andreas Ludwig; Fi-Tjen Mu; Gabrielle J Pennings; Jianlin Qiao; Chee Wee Tan; Christopher M Ward; Andy S C Yong; Elizabeth E Gardiner
Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels.
Blood 2012;119(18):4311-20.
2012: M Al-Tamimi; Jane F Arthur; Elizabeth E Gardiner; Robert K Andrews
Focusing on plasma glycoprotein VI.
Thrombosis and haemostasis 2012;107(4):648-55.
2012: Robert K Andrews; Elizabeth E Gardiner
Inside platelets...
Blood 2012;119(4):907-9.
2012: Jianlin Qiao; Yang Shen; Fi-Tjen Mu; Robert K Andrews; Jane F Arthur; Michael C Berndt; Margaret Collecutt; Amanda K Davis; Elizabeth E Gardiner
An acquired defect associated with abnormal signaling of the platelet collagen receptor glycoprotein VI.
Acta haematologica 2012;128(4):233-41.
2012: Elizabeth E Gardiner; Mohammad Al-Tamimi; Robert K Andrews; Michael C Berndt
Platelet receptor shedding.
Methods in molecular biology (Clifton, N.J.) 2012;788():321-39.
2011: Simone M Schoenwaelder; Michael J White; Abbey Willcox; Imala Alwis; Robert K Andrews; Elizabeth E Gardiner; My Hua; David C S Huang; Kate E Jarman; Emma C Josefsson; Benjamin T Kile; Kylie D Mason; Akiko Ono; Jianlin Qiao; Andrew W Roberts; Hatem H Salem; Shaun P Jackson
Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets.
Blood 2011;118(6):1663-74.
2011: Mohammad Al-Tamimi; George Grigoriadis; Huy Tran; Eldho Paul; Patricia Servadei; Michael C Berndt; Elizabeth E Gardiner; Robert K Andrews
Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa.
Blood 2011;117(14):3912-20.
2011: Susan L Cranmer; Katrina J Ashworth; Yu Yao; Michael C Berndt; Zaverio M Ruggeri; Robert K Andrews; Shaun P Jackson
High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction.
Blood 2011;117(9):2718-27.
2011: Mohammad Al-Tamimi; Elizabeth E Gardiner; Jim Y Thom; Yang Shen; Matthew N Cooper; Graeme J Hankey; Michael C Berndt; Ross Baker; Robert K Andrews
Soluble glycoprotein VI is raised in the plasma of patients with acute ischemic stroke.
Stroke; a journal of cerebral circulation 2011;42(2):498-500.
2011: Robert K Andrews; Michael C Berndt
An event of shear importance.
Blood 2011;117(1):5-7.
2011: Jane F Arthur; Yang Shen; Elizabeth E Gardiner; L Coleman; D Kenny; Robert K Andrews; Derek Murphy; Michael C Berndt
TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets.
Journal of thrombosis and haemostasis : JTH 2011;9(1):163-72.
2010: Xi Mo; Nam X Nguyen; Fi-Tjen Mu; Wenjun Yang; Shi-Zhong Luo; Huizhou Fan; Robert K Andrews; Michael C Berndt; Renhao Li
Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha.
The Journal of biological chemistry 2010;285(42):32096-104.
2010: Jian L Qiao; Yang Shen; Elizabeth E Gardiner; Robert K Andrews
Proteolysis of platelet receptors in humans and other species.
Biological chemistry 2010;391(8):893-900.
2010: Lakshmi C Wijeyewickrema; Elizabeth E Gardiner; Elsa L Gladigau; Michael C Berndt; Robert K Andrews
Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI.
The Journal of biological chemistry 2010;285(16):11793-9.
2010: Fi-Tjen Mu; Susan L Cranmer; Robert K Andrews; Michael C Berndt
Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibalpha, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex.
Journal of thrombosis and haemostasis : JTH 2010;8(2):324-30.
2010: Elizabeth E Gardiner; Jane F Arthur; Yang Shen; Denuja Karunakaran; Lynley A Moore; Jan Schulte Am Esch; Robert K Andrews; Michael C Berndt
GPIbalpha-selective activation of platelets induces platelet signaling events comparable to GPVI activation events.
Platelets 2010;21(4):244-52.
2009: Andrew H Wei; Simone M Schoenwaelder; Robert K Andrews; Shaun P Jackson
New insights into the haemostatic function of platelets.
British journal of haematology 2009;147(4):415-30.
2009: Mohammad Al-Tamimi; Fi-Tjen Mu; Masaaki Moroi; Elizabeth E Gardiner; Michael C Berndt; Robert K Andrews
Measuring soluble platelet glycoprotein VI in human plasma by ELISA.
Platelets 2009;20(3):143-9.
2009: Zon W Lai; Rebecca A Lew; Michael A Yarski; Fi-Tjen Mu; Robert K Andrews; A Ian Smith
The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2.
Endocrinology 2009;150(5):2376-81.
2009: Mohammad Al-Tamimi; Fi-Tjen Mu; Jane F Arthur; Yang Shen; Masaaki Moroi; Michael C Berndt; Robert K Andrews; Elizabeth E Gardiner
Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding.
Platelets 2009;20(2):75-82.
2008: Marguerite S Buzza; Jennifer M Dyson; Hiuwan Choi; Elizabeth E Gardiner; Robert K Andrews; Dion Kaiserman; Christina A Mitchell; Michael C Berndt; Jing-Fei Dong; Phillip I Bird
Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor.
The Journal of biological chemistry 2008;283(33):22498-504.
2008: Elizabeth E Gardiner; Robert K Andrews
The cut of the clot(h): snake venom fibrinogenases as therapeutic agents.
Journal of thrombosis and haemostasis : JTH 2008;6(8):1360-2.
2008: Elizabeth E Gardiner; M Al-Tamimi; Fi-Tjen Mu; Denuja Karunakaran; J Y Thom; Masaaki Moroi; Robert K Andrews; Michael C Berndt; Ross Baker
Compromised ITAM-based platelet receptor function in a patient with immune thrombocytopenic purpura.
Journal of thrombosis and haemostasis : JTH 2008;6(7):1175-82.
2008: Fi-Tjen Mu; Robert K Andrews; Jane F Arthur; Adam D Munday; Susan L Cranmer; Shaun P Jackson; Frank C Stomski; Angel F Lopez; Michael C Berndt
A functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex.
Blood 2008;111(9):4580-7.
2008: Jane F Arthur; Elizabeth E Gardiner; Dermot Kenny; Robert K Andrews; Michael C Berndt
Platelet receptor redox regulation.
Platelets 2008;19(1):1-8.
2008: Elizabeth E Gardiner; Denuja Karunakaran; Jane F Arthur; Fi-Tjen Mu; Maree S Powell; Ross Baker; P Mark Hogarth; Mark L Kahn; Robert K Andrews; Michael C Berndt
Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa.
Blood 2008;111(1):165-74.
2007: Lakshmi C Wijeyewickrema; Elizabeth E Gardiner; Yang Shen; Michael C Berndt; Robert K Andrews
Fractionation of snake venom metalloproteinases by metal ion affinity: a purified cobra metalloproteinase, Nk, from Naja kaouthia binds Ni2+-agarose.
Toxicon : official journal of the International Society on Toxinology 2007;50(8):1064-72.
2007: Lakshmi C Wijeyewickrema; Elizabeth E Gardiner; Masaaki Moroi; Michael C Berndt; Robert K Andrews
Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI.
Thrombosis and haemostasis 2007;98(6):1285-90.
2007: Jane F Arthur; Scott Dunkley; Robert K Andrews
Platelet glycoprotein VI-related clinical defects.
British journal of haematology 2007;139(3):363-72.
2007: Jane F Arthur; Yang Shen; Mark L Kahn; Michael C Berndt; Robert K Andrews; Elizabeth E Gardiner
Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane.
The Journal of biological chemistry 2007;282(42):30434-41.
2007: Michael C Berndt; Denuja Karunakaran; Elizabeth E Gardiner; Robert K Andrews
Programmed autologous cleavage of platelet receptors.
Journal of thrombosis and haemostasis : JTH 2007;5 Suppl 1():212-9.
2007: Robert K Andrews; Denuja Karunakaran; Elizabeth E Gardiner; Michael C Berndt
Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(7):1511-20.
2007: Elizabeth E Gardiner; Denuja Karunakaran; Yang Shen; Jane F Arthur; Robert K Andrews; Michael C Berndt
Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases.
Journal of thrombosis and haemostasis : JTH 2007;5(7):1530-7.
2007: Robert K Andrews; Xiaoping Du; Michael C Berndt
The 14-3-3zeta-GPIb-IX-V complex as an antiplatelet target.
Drug news & perspectives 2007;20(5):285-92.
2007: Scott Dunkley; Jane F Arthur; Sue Evans; Elizabeth E Gardiner; Yang Shen; Robert K Andrews
A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway.
British journal of haematology 2007;137(6):569-77.
2006: Jane F Arthur; Yang Shen; Fi-Tjen Mu; Catherine Leon; Christian Gachet; Michael C Berndt; Robert K Andrews
Calmodulin interacts with the platelet ADP receptor P2Y1.
The Biochemical journal 2006;398(3):339-43.
2006: Yang Shen; Susan L Cranmer; Andrea Aprico; James C Whisstock; Shaun P Jackson; Michael C Berndt; Robert K Andrews
Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor.
The Journal of biological chemistry 2006;281(36):26419-23.
2005: Elizabeth E Gardiner; Jane F Arthur; Michael C Berndt; Robert K Andrews
Role of calmodulin in platelet receptor function.
Current medicinal chemistry. Cardiovascular and hematological agents 2005;3(4):283-7.
2005: Lakshmi C Wijeyewickrema; Michael C Berndt; Robert K Andrews
Snake venom probes of platelet adhesion receptors and their ligands.
Toxicon : official journal of the International Society on Toxinology 2005;45(8):1051-61.
2005: Jane F Arthur; Elizabeth E Gardiner; Maria Matzaris; Simon G Taylor; Lakshmi C Wijeyewickrema; Yukio Ozaki; Mark L Kahn; Robert K Andrews; Michael C Berndt
Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets.
Thrombosis and haemostasis 2005;93(4):716-23.
2005: Jana Yip; Yang Shen; Michael C Berndt; Robert K Andrews
Primary platelet adhesion receptors.
IUBMB life 2005;57(2):103-8.
2004: Elizabeth E Gardiner; Jane F Arthur; Mark L Kahn; Michael C Berndt; Robert K Andrews
Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase.
Blood 2004;104(12):3611-7.
2004: Katsue Suzuki-Inoue; Jonathan Wilde; Robert K Andrews; Jocelyn M Auger; Reuben P Siraganian; Fujio Sekiya; Sue Goo Rhee; Steve P Watson
Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.
The Biochemical journal 2004;378(Pt 3):1023-9.
2004: Robert K Andrews; Michael C Berndt
Platelet physiology and thrombosis.
Thrombosis research 2004;114(5-6):447-53.
2004: Robert K Andrews; Elizabeth E Gardiner; Michael C Berndt
Snake venom toxins affecting platelet function.
Methods in molecular biology (Clifton, N.J.) 2004;273():335-48.
2004: Robert K Andrews; Elizabeth E Gardiner; Yang Shen; Michael C Berndt
Platelet interactions in thrombosis.
IUBMB life 2004;56(1):13-8.
2003: Robert K Andrews; E E Gardiner; Y Shen; J C Whisstock; M C Berndt
Glycoprotein Ib-IX-V.
The international journal of biochemistry & cell biology 2003;35(8):1170-4.
2003: Robert K Andrews; Elizabeth E Gardiner; Yang Shen; Michael C Berndt
Structure-activity relationships of snake toxins targeting platelet receptors, glycoprotein Ib-IX-V and glycoprotein VI.
Current medicinal chemistry. Cardiovascular and hematological agents 2003;1(2):143-9.
2003: Robert K Andrews; Michael C Berndt
Platelet physiology: in cold blood.
Current biology : CB 2003;13(7):R282-4.
2002: Katsue Suzuki-Inoue; David Tulasne; Yang Shen; TERESA BORI-SANZ; Osamu Inoue; Stephanie M Jung; Masaaki Moroi; Robert K Andrews; Michael C Berndt; Steve P Watson
Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling.
The Journal of biological chemistry 2002;277(24):21561-6.
2002: Robert K Andrews; Katsue Suzuki-Inoue; Yang Shen; David Tulasne; Steve P Watson; Michael C Berndt
Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI.
Blood 2002;99(11):4219-21.
2002: James C Whisstock; Yang Shen; José A López; Robert K Andrews; Michael C Berndt
Molecular modeling of the seven tandem leucine-rich repeats within the ligand-binding region of platelet glycoprotein Ib alpha.
Thrombosis and haemostasis 2002;87(2):329-33.
2002: Stuart J Marshall; Naoki Asazuma; Denise Best; Peter Wonerow; Gary Salmon; Robert K Andrews; Steve P Watson
Glycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathway.
The Biochemical journal 2002;361(Pt 2):297-305.
2002: Yang Shen; Jing-fei Dong Jf; Gabriel M Romo; Wendy Arceneaux; Andrea Aprico; Elizabeth E Gardiner; José A López; Michael C Berndt; Robert K Andrews
Functional analysis of the C-terminal flanking sequence of platelet glycoprotein Ib alpha using canine-human chimeras.
Blood 2002;99(1):145-50.
2001: Elizabeth E Gardiner; M De Luca; T McNally; A D Michelson; Robert K Andrews; Michael C Berndt
Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor P-selectin glycoprotein ligand-1 by neutrophil elastase and cathepsin G.
Blood 2001;98(5):1440-7.
2001: Robert K Andrews; Adam D Munday; Christina A Mitchell; Michael C Berndt
Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex.
Blood 2001;98(3):681-7.
2001: Robert K Andrews; Elizabeth E Gardiner; Naoki Asazuma; Oscar Berlanga; David Tulasne; B Nieswandt; A I Smith; Michael C Berndt; Steve P Watson
A novel viper venom metalloproteinase, alborhagin, is an agonist at the platelet collagen receptor GPVI.
The Journal of biological chemistry 2001;276(30):28092-7.
2001: Robert K Andrews; Y Shen; E E Gardiner; M C Berndt
Platelet adhesion receptors and (patho)physiological thrombus formation.
Histology and histopathology 2001;16(3):969-80.
2001: Michael C Berndt; Yang Shen; S M Dopheide; Elizabeth E Gardiner; Robert K Andrews
The vascular biology of the glycoprotein Ib-IX-V complex.
Thrombosis and haemostasis 2001;86(1):178-88.
2001: Naoki Asazuma; Stuart J Marshall; Oscar Berlanga; Daniel C Snell; A W Poole; Michael C Berndt; Robert K Andrews; Steve P Watson
The snake venom toxin alboaggregin-A activates glycoprotein VI.
Blood 2001;97(12):3989-91.
2001: Robert K Andrews; Aura S Kamiguti; Oscar Berlanga; Mireille Leduc; R David G Theakston; Steve P Watson
The use of snake venom toxins as tools to study platelet receptors for collagen and von Willebrand factor.
Haemostasis 2001;31(3-6):155-72.
2001: Jing-fei Dong; Michael C Berndt; Alicia J Schade; Larry V McIntire; Robert K Andrews; José A López
Ristocetin-dependent, but not botrocetin-dependent, binding of von Willebrand factor to the platelet glycoprotein Ib-IX-V complex correlates with shear-dependent interactions.
Blood 2001;97(1):162-8.
2000: J Dong; Alicia J Schade; Gabriel M Romo; Robert K Andrews; Shan Gao; Larry V McIntire; José A López
Novel gain-of-function mutations of platelet glycoprotein IBalpha by valine mutagenesis in the Cys209-Cys248 disulfide loop. Functional analysis under statis and dynamic conditions.
The Journal of biological chemistry 2000;275(36):27663-70.
2000: Robert K Andrews; Michael C Berndt
Snake venom modulators of platelet adhesion receptors and their ligands.
Toxicon : official journal of the International Society on Toxinology 2000;38(6):775-91.
2000: Yang Shen; Gabriel M Romo; Jing-fei Dong; Alicia J Schade; Larry V McIntire; D Kenny; J C Whisstock; Michael C Berndt; José A López; Robert K Andrews
Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex.
Blood 2000;95(3):903-10.
2000: M De Luca; DA Facey; Emmanuel Favaloro; Mark Hertzberg; J C Whisstock; T McNally; Robert K Andrews; Michael C Berndt
Structure and function of the von Willebrand factor A1 domain: analysis with monoclonal antibodies reveals distinct binding sites involved in recognition of the platelet membrane glycoprotein Ib-IX-V complex and ristocetin-dependent activation.
Blood 2000;95(1):164-72.
1999: Robert K Andrews; Yang Shen; Elizabeth E Gardiner; Jing-fei Dong; José A López; Michael C Berndt
The glycoprotein Ib-IX-V complex in platelet adhesion and signaling.
Thrombosis and haemostasis 1999;82(2):357-64.
1998: Robert K Andrews; Michael C Berndt
Adhesion-dependent signalling and the initiation of haemostasis and thrombosis.
Histology and histopathology 1998;13(3):837-44.
1998: José A López; Robert K Andrews; Vahid Afshar-Kharghan; Michael C Berndt
Bernard-Soulier syndrome.
Blood 1998;91(12):4397-418.
1998: Robert K Andrews; S J Harris; T McNally; Michael C Berndt
Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex.
Biochemistry 1998;37(2):638-47.
1997: J K Campbell; Rajendra Gurung; S Romero; Caroline J Speed; Robert K Andrews; Michael C Berndt; Christina A Mitchell
Activation of the 43 kDa inositol polyphosphate 5-phosphatase by 14-3-3zeta.
Biochemistry 1997;36(49):15363-70.
1997: C M Ward; T J Tetaz; Robert K Andrews; Michael C Berndt
Binding of the von Willebrand factor A1 domain to histone.
Thrombosis research 1997;86(6):469-77.
1997: Robert K Andrews; José A López; Michael C Berndt
Molecular mechanisms of platelet adhesion and activation.
The international journal of biochemistry & cell biology 1997;29(1):91-105.
1996: C M Ward; D V Vinogradov; Robert K Andrews; M C Berndt
Characterization of mocarhagin, a cobra venom metalloproteinase from Naja mocambique mocambique, and related proteins from other Elapidae venoms.
Toxicon : official journal of the International Society on Toxinology 1996;34(10):1203-6.
1996: Robert K Andrews; M H Kroll; C M Ward; Jack W Rose; Robert M Scarborough; A I Smith; José A López; M C Berndt
Binding of a novel 50-kilodalton alboaggregin from Trimeresurus albolabris and related viper venom proteins to the platelet membrane glycoprotein Ib-IX-V complex. Effect on platelet aggregation and glycoprotein Ib-mediated platelet activation.
Biochemistry 1996;35(38):12629-39.
1996: C M Ward; Robert K Andrews; A I Smith; M C Berndt
Mocarhagin, a novel cobra venom metalloproteinase, cleaves the platelet von Willebrand factor receptor glycoprotein Ibalpha. Identification of the sulfated tyrosine/anionic sequence Tyr-276-Glu-282 of glycoprotein Ibalpha as a binding site for von Willebrand factor and alpha-thrombin.
Biochemistry 1996;35(15):4929-38.
1995: M C Berndt; C M Ward; M De Luca; D A Facey; P A Castaldi; S J Harris; Robert K Andrews
The molecular mechanism of platelet adhesion.
Australian and New Zealand journal of medicine 1995;25(6):822-30.
1995: M De Luca; L C Dunlop; Robert K Andrews; J V Flannery; R Ettling; D A Cumming; G M Veldman; M C Berndt
A novel cobra venom metalloproteinase, mocarhagin, cleaves a 10-amino acid peptide from the mature N terminus of P-selectin glycoprotein ligand receptor, PSGL-1, and abolishes P-selectin binding.
The Journal of biological chemistry 1995;270(45):26734-7.
1995: M De Luca; C M Ward; K Ohmori; Robert K Andrews; M C Berndt
Jararhagin and jaracetin: novel snake venom inhibitors of the integrin collagen receptor, alpha 2 beta 1.
Biochemical and biophysical research communications 1995;206(2):570-6.
1995: Robert K Andrews; L J Bendall; W J Booth; M C Berndt
Inhibition of Binding of von Willebrand Factor to the Platelet Glycoprotein Ib-IX Complex, Heparin and Sulfatides by Polyanionic Compounds. The Mechanism of Modulation of the Adhesive Function of von Willebrand Factor.
Platelets 1995;6(5):252-8.
1995: Robert K Andrews; W J Booth; L J Bendall; M C Berndt
The amino Acid sequence glutamine-628 to valine-646 within the A1 repeat domain mediates binding of von Willebrand factor to bovine brain sulfatides and equine tendon collagen.
Platelets 1995;6(5):245-51.
1992: M C Berndt; C M Ward; W J Booth; P A Castaldi; Alexey V Mazurov; Robert K Andrews
Identification of aspartic acid 514 through glutamic acid 542 as a glycoprotein Ib-IX complex receptor recognition sequence in von Willebrand factor. Mechanism of modulation of von Willebrand factor by ristocetin and botrocetin.
Biochemistry 1992;31(45):11144-51.
1990: W J Booth; Robert K Andrews; P A Castaldi; M C Berndt
The Interaction of von Willebrand Factor and the Platelet Glycoprotein Ib-IX Complex.
Platelets 1990;1(4):169-76.
1989: M P Skinner; D J Fournier; Robert K Andrews; Jeffrey J Gorman; C N Chesterman; M C Berndt
Characterization of human platelet GMP-140 as a heparin-binding protein.
Biochemical and biophysical research communications 1989;164(3):1373-9.
1989: Robert K Andrews; Jeffrey J Gorman; W J Booth; G L Corino; P A Castaldi; M C Berndt
Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val-481-Gly-718) to the N-terminal region of the alpha-chain of membrane glycoprotein Ib on intact platelets with bis(sulfosuccinimidyl) suberate.
Biochemistry 1989;28(21):8326-36.
1989: Robert K Andrews; W J Booth; Jeffrey J Gorman; P A Castaldi; M C Berndt
Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex.
Biochemistry 1989;28(21):8317-26.