FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Larry Feig

Research Profile

Chemicals & Drugs

Living Beings

Mouse

Physiology

Anatomy

Co-author Network

Publications

TOP 3
Lorena Saavedra-Rodríguez; Larry A Feig
Chronic social instability induces anxiety and defective social interactions across generations.
Addy Alt-Holland; Larry A Feig; Harold Hatch; Yulia Shamis; Adam Sowalsky; Yonit Szwec-Levin; Jonathan A Garlick
Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src.
Junko A Arai; Larry A Feig
Long-lasting and transgenerational effects of an environmental enrichment on memory formation.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Larry Feig (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Lorena Saavedra-Rodríguez; Larry A Feig
Chronic social instability induces anxiety and defective social interactions across generations.
Biological psychiatry 2013;73(1):44-53.
2011: Addy Alt-Holland; Larry A Feig; Harold Hatch; Yulia Shamis; Adam Sowalsky; Yonit Szwec-Levin; Jonathan A Garlick
Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src.
The Journal of investigative dermatology 2011;131(11):2306-15.
2011: Junko A Arai; Larry A Feig
Long-lasting and transgenerational effects of an environmental enrichment on memory formation.
Brain research bulletin 2011;85(1-2):30-5.
2011: Larry A Feig
Regulation of Neuronal Function by Ras-GRF Exchange Factors.
Genes & cancer 2011;2(3):306-19.
2011: Adam Sowalsky; Addy Alt-Holland; Yulia Shamis; Jonathan A Garlick; Larry A Feig
RalA function in dermal fibroblasts is required for the progression of squamous cell carcinoma of the skin.
Cancer research 2011;71(3):758-67.
2010: Adam Sowalsky; A Alt-Holland; Y Shamis; J A Garlick; Larry A Feig
RalA suppresses early stages of Ras-induced squamous cell carcinoma progression.
Oncogene 2010;29(1):45-55.
2010: Shan-Xue Jin; Larry A Feig
Long-term potentiation in the CA1 hippocampus induced by NR2A subunit-containing NMDA glutamate receptors is mediated by Ras-GRF2/Erk map kinase signaling.
PloS one 2010;5(7):e11732.
2009: Junko A Arai; Shaomin Li; Larry A Feig
Sos2 is dispensable for NMDA-induced Erk activation and LTP induction.
Neuroscience letters 2009;455(1):22-5.
2009: Junko A Arai; Shaomin Li; Dean Hartley; Larry A Feig
Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(5):1496-502.
2008: Yansheng Hao; Richard Wong; Larry A Feig
RalGDS couples growth factor signaling to Akt activation.
Molecular and cellular biology 2008;28(9):2851-9.
2007: Shaomin Li; Larry A Feig; Dean Hartley
A brief, but repeated, swimming protocol is sufficient to overcome amyloid beta-protein inhibition of hippocampal long-term potentiation.
The European journal of neuroscience 2007;26(5):1289-98.
2006: Shaomin Li; Xuejun Tian; Dean Hartley; Larry A Feig
The environment versus genetics in controlling the contribution of MAP kinases to synaptic plasticity.
Current biology : CB 2006;16(23):2303-13.
2006: Jie Wei; Sebastian Fain; Celia Harrison; Larry A Feig; James D Baleja
Molecular dissection of Rab11 binding from coiled-coil formation in the Rab11-FIP2 C-terminal domain.
Biochemistry 2006;45(22):6826-34.
2006: Larry A Feig
The odyssey of k-ras.
Molecular cell 2006;21(4):447-9.
2006: Shaomin Li; Xuejun Tian; Dean Hartley; Larry A Feig
Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(6):1721-9.
2005: Kian-Huat Lim; Antonio T Baines; James J Fiordalisi; Michail Shipitsin; Larry A Feig; Adrienne D Cox; Channing J Der; Christopher M Counter
Activation of RalA is critical for Ras-induced tumorigenesis of human cells.
Cancer cell 2005;7(6):533-45.
2005: Beth A Connolly; Jared Rice; Larry A Feig; Rachel J Buchsbaum
Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation.
Molecular and cellular biology 2005;25(11):4602-14.
2005: Gabriel Rusanescu; Wentian Yang; Ailin Bai; Benjamin G Neel; Larry A Feig
Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity.
The EMBO journal 2005;24(2):305-14.
2004: Michail Shipitsin; Larry A Feig
RalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cells.
Molecular and cellular biology 2004;24(13):5746-56.
2004: Xuejun Tian; Takaya Gotoh; Kiyoshi Tsuji; Eng H Lo; Su Huang; Larry A Feig
Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB.
The EMBO journal 2004;23(7):1567-75.
2003: Larry A Feig
Ral-GTPases: approaching their 15 minutes of fame.
Trends in cell biology 2003;13(8):419-25.
2003: Rachel J Buchsbaum; Beth A Connolly; Larry A Feig
Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin.
The Journal of biological chemistry 2003;278(21):18833-41.
2002: Donald N Cullis; Betsey Philip; James D Baleja; Larry A Feig
Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors.
The Journal of biological chemistry 2002;277(51):49158-66.
2002: Yi Yu; Larry A Feig
Involvement of R-Ras and Ral GTPases in estrogen-independent proliferation of breast cancer cells.
Oncogene 2002;21(49):7557-68.
2002: Rachel J Buchsbaum; Beth A Connolly; Larry A Feig
Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade.
Molecular and cellular biology 2002;22(12):4073-85.
2002: Larry A Feig; Rachel J Buchsbaum
Cell signaling: life or death decisions of ras proteins.
Current biology : CB 2002;12(7):R259-61.
2002: Xuejun Tian; Gabriel Rusanescu; Weimin Hou; Brian Schaffhausen; Larry A Feig
PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism.
The EMBO journal 2002;21(6):1327-38.
2002: Atsuko Polzin; Michail Shipitsin; Takanori Goi; Larry A Feig; Timothy J Turner
Ral-GTPase influences the regulation of the readily releasable pool of synaptic vesicles.
Molecular and cellular biology 2002;22(6):1714-22.
2001: Xuejun Tian; Larry A Feig
Basis for signaling specificity difference between Sos and Ras-GRF guanine nucleotide exchange factors.
The Journal of biological chemistry 2001;276(50):47248-56.
2001: Takaya Gotoh; Xuejun Tian; Larry A Feig
Prenylation of target GTPases contributes to signaling specificity of Ras-guanine nucleotide exchange factors.
The Journal of biological chemistry 2001;276(41):38029-35.
2001: S Kim; D N Cullis; Larry A Feig; James D Baleja
Solution structure of the Reps1 EH domain and characterization of its binding to NPF target sequences.
Biochemistry 2001;40(23):6776-85.
2001: Virginia Ladeda; Paul Frankel; Larry A Feig; David A Foster; Elisa Bal De Kier Joffe; Julio A Aguirre Ghiso
RalA mediates v-Src, v-Ras, and v-Raf regulation of CD44 and fibronectin expression in NIH3T3 fibroblasts.
Biochemical and biophysical research communications 2001;283(4):854-61.
2001: Gabriel Rusanescu; Takaya Gotoh; Xuejun Tian; Larry A Feig
Regulation of Ras signaling specificity by protein kinase C.
Molecular and cellular biology 2001;21(8):2650-8.
2000: S Kim; A M Dubelman; S Goonesekera; Larry A Feig; James D Baleja
1H, 15N, and 13C NMR resonance assignments for the Eps15 homology domain of Reps1.
Journal of biomolecular NMR 2000;18(4):367-8.
2000: Takaya Gotoh; D Cai; Xuejun Tian; Larry A Feig; A Lerner
p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.
The Journal of biological chemistry 2000;275(39):30118-23.
2000: Takanori Goi; Michail Shipitsin; Z Lu; David A Foster; S G Klinz; Larry A Feig
An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity.
The EMBO journal 2000;19(4):623-30.
2000: Zhimin Lu; Armand Hornia; Troy Joseph; T Sukezane; Paul Frankel; Minghao Zhong; S Bychenok; Lizhong Xu; Larry A Feig; David A Foster
Phospholipase D and RalA cooperate with the epidermal growth factor receptor to transform 3Y1 rat fibroblasts.
Molecular and cellular biology 2000;20(2):462-7.
1999: Julio A Aguirre Ghiso; Paul Frankel; Eduardo Francisco Farias; Zhimin Lu; H Jiang; A Olsen; Larry A Feig; E B de Kier Joffe; David A Foster
RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases.
Oncogene 1999;18(33):4718-25.
1999: Larry A Feig
Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases.
Nature cell biology 1999;1(2):E25-7.
1999: Takanori Goi; Gabriel Rusanescu; T Urano; Larry A Feig
Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth.
Molecular and cellular biology 1999;19(3):1731-41.
1999: Paul Frankel; M Ramos; J Flom; S Bychenok; Troy Joseph; E Kerkhoff; U R Rapp; Larry A Feig; David A Foster
Ral and Rho-dependent activation of phospholipase D in v-Raf-transformed cells.
Biochemical and biophysical research communications 1999;255(2):502-7.
1998: JQ Luo; X Liu; Paul Frankel; Thuy Rotunda; M Ramos; J Flom; H Jiang; Larry A Feig; Andrew J Morris; Richard A Kahn; David A Foster
Functional association between Arf and RalA in active phospholipase D complex.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3632-7.
1997: A Yamaguchi; T Urano; Takanori Goi; Larry A Feig
An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1.
The Journal of biological chemistry 1997;272(50):31230-4.
1997: JQ Luo; X Liu; Scott M Hammond; WC Colley; Larry A Feig; Michael A Frohman; Andrew J Morris; David A Foster
RalA interacts directly with the Arf-responsive, PIP2-dependent phospholipase D1.
Biochemical and biophysical research communications 1997;235(3):854-9.
1997: Norman Freshney; S D Goonesekera; Larry A Feig
Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain.
FEBS letters 1997;407(1):111-5.
1996: R Buchsbaum; J B Telliez; S Goonesekera; Larry A Feig
The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium.
Molecular and cellular biology 1996;16(9):4888-96.
1996: T Urano; R Emkey; Larry A Feig
Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation.
The EMBO journal 1996;15(4):810-6.
1995: H Jiang; J Q Luo; T Urano; Paul Frankel; Zhimin Lu; David A Foster; Larry A Feig
Involvement of Ral GTPase in v-Src-induced phospholipase D activation.
Nature 1995;378(6555):409-12.
1995: C L Farnsworth; Norman Freshney; L B Rosen; A Ghosh; M E Greenberg; Larry A Feig
Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.
Nature 1995;376(6540):524-7.
1995: S B Cantor; T Urano; Larry A Feig
Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases.
Molecular and cellular biology 1995;15(8):4578-84.
1995: C Shou; A Wurmser; K L Suen; M Barbacid; Larry A Feig; K Ling
Differential response of the Ras exchange factor, Ras-GRF to tyrosine kinase and G protein mediated signals.
Oncogene 1995;10(10):1887-93.
1995: S T Dillon; E J Rubin; M Yakubovich; C Pothoulakis; J T LaMont; Larry A Feig; R J Gilbert
Involvement of Ras-related Rho proteins in the mechanisms of action of Clostridium difficile toxin A and toxin B.
Infection and immunity 1995;63(4):1421-6.
1995: S T Dillon; Larry A Feig
Purification and assay of recombinant C3 transferase.
Methods in enzymology 1995;256():174-84.
1994: Larry A Feig
Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases.
Current opinion in cell biology 1994;6(2):204-11.
1992: C Shou; C L Farnsworth; B G Neel; Larry A Feig
Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21.
Nature 1992;358(6384):351-4.
1991: Dennis W Stacey; M Roudebush; R Day; Scott D Mosser; Jackson B Gibbs; Larry A Feig
Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes.
Oncogene 1991;6(12):2297-304.
1991: C L Farnsworth; Larry A Feig
Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.
Molecular and cellular biology 1991;11(10):4822-9.
1991: John D Hildebrandt; R Day; C L Farnsworth; Larry A Feig
A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.
Molecular and cellular biology 1991;11(10):4830-8.
1991: Dennis W Stacey; Larry A Feig; Jackson B Gibbs
Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.
Molecular and cellular biology 1991;11(8):4053-64.
1991: R Emkey; S Freedman; Larry A Feig
Characterization of a GTPase-activating protein for the Ras-related Ral protein.
The Journal of biological chemistry 1991;266(15):9703-6.
1991: C L Farnsworth; M S Marshall; Jackson B Gibbs; Dennis W Stacey; Larry A Feig
Preferential inhibition of the oncogenic form of RasH by mutations in the GAP binding/"effector" domain.
Cell 1991;64(3):625-33.
1988: Larry A Feig; G M Cooper
Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.
Molecular and cellular biology 1988;8(8):3235-43.
1988: Larry A Feig; G M Cooper
Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins.
Molecular and cellular biology 1988;8(6):2472-8.