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Andrew Feinberg
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22
Cui, Hengmi
16
Lee, Maxwell
12
Vogelstein, Bert
11
Brandenburg, Sheri
9
DeBaun, Michael
9
Onyango, Patrick
8
Niemitz, Emily
8
Rainier, Shirley
8
Law, David
7
Oshimura, Mitsuo
6
Watanabe, KA
6
Hu, RJ
6
Irizarry, Rafael
5
Grundy, Paul
5
Gius, David
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All Publications
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2009: Cruz-Correa Marcia; Zhao Ronghua; Oviedo Myriam; Bernabe Raul D; Lacourt Mercedes; Cardona Alberto; Lopez-Enriquez Reynold; Wexner Steven; Cuffari Carmen; Hylind Linda; Platz Elizabeth; Cui Hengmi; Feinberg Andrew P; Giardiello Francis M
Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene.
Epigenetics : official journal of the DNA Methylation Society 2009;4(2):114-8.
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2009: Mirsaidov U; Timp W; Zou X; Dimitrov V; Schulten K; Feinberg A P; Timp G
Nanoelectromechanics of methylated DNA in a synthetic nanopore.
Biophysical journal 2009;96(4):L32-4.
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2009: Timp Winston; Levchenko Andre; Feinberg Andrew P
A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction.
Cell cycle (Georgetown, Tex.) 2009;8(3):383-90.
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2009: Wen Bo; Wu Hao; Shinkai Yoichi; Irizarry Rafael A; Feinberg Andrew P
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells.
Nature genetics 2009;41(2):246-50.
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2009: Irizarry Rafael A; Ladd-Acosta Christine; Wen Bo; Wu Zhijin; Montano Carolina; Onyango Patrick; Cui Hengmi; Gabo Kevin; Rongione Michael; Webster Maree; Ji Hong; Potash James B; Sabunciyan Sarven; Feinberg Andrew P
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores.
Nature genetics 2009;41(2):178-86.
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2008: Wen Bo; Wu Hao; Bjornsson Hans; Green Roland D; Irizarry Rafael; Feinberg Andrew P
Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification.
Genome research 2008;18(11):1806-13.
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2008: Nguyen Phuongmai; Bar-Sela Gil; Sun Lunching; Bisht Kheem S; Cui Hengmi; Kohn Elise; Feinberg Andrew P; Gius David
BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression.
Molecular and cellular biology 2008;28(21):6720-9.
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2008: Nguyen Phuongmai; Cui Hengmi; Bisht Kheem S; Sun Lunching; Patel Krish; Lee Richard S; Kugoh Hiroyuki; Oshimura Mitsuo; Feinberg Andrew P; Gius David
CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region.
Cancer research 2008;68(14):5546-51.
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2008: Bjornsson Hans T; Sigurdsson Martin I; Fallin M Daniele; Irizarry Rafael A; Aspelund Thor; Cui Hengmi; Yu Wenqiang; Rongione Michael A; Ekström Tomas J; Harris Tamara B; Launer Lenore J; Eiriksdottir Gudny; Leppert Mark F; Sapienza Carmen; Gudnason Vilmundur; Feinberg Andrew P
Intra-individual change over time in DNA methylation with familial clustering.
JAMA : the journal of the American Medical Association 2008;299(24):2877-83.
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2008: Bjornsson Hans T; Albert Thomas J; Ladd-Acosta Christine M; Green Roland D; Rongione Michael A; Middle Christina M; Irizarry Rafael A; Broman Karl W; Feinberg Andrew P
SNP-specific array-based allele-specific expression analysis.
Genome research 2008;18(5):771-9.
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2008: Irizarry Rafael A; Ladd-Acosta Christine; Carvalho Benilton; Wu Hao; Brandenburg Sheri A; Jeddeloh Jeffrey A; Wen Bo; Feinberg Andrew P
Comprehensive high-throughput arrays for relative methylation (CHARM).
Genome research 2008;18(5):780-90.
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2008: Sun Lunching; Huang Lei; Nguyen Phuongmai; Bisht Kheem S; Bar-Sela Gil; Ho Allen S; Bradbury C Matthew; Yu Wenqiang; Cui Hengmi; Lee Sunmin; Trepel Jane B; Feinberg Andrew P; Gius David
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.
Cancer research 2008;68(8):2726-35.
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2008: Feinberg Andrew P
Epigenetics at the epicenter of modern medicine.
JAMA : the journal of the American Medical Association 2008;299(11):1345-50.
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2008: Yu Wenqiang; Gius David; Onyango Patrick; Muldoon-Jacobs Kristi; Karp Judith; Feinberg Andrew P; Cui Hengmi
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA.
Nature 2008;451(7175):202-6.
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2008: Potash James B; Buervenich Silvia; Cox Nancy J; Zandi Peter P; Akula Nirmala; Steele Jo; Rathe Jennifer A; Avramopoulos Dimitrios; Detera-Wadleigh Sevilla D; Gershon Elliot S; DePaulo J Raymond; Feinberg Andrew P; McMahon Francis J;
Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(1):59-67.
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2007: Kaneda Atsushi; Wang Chiaochun J; Cheong Raymond; Timp Winston; Onyango Patrick; Wen Bo; Iacobuzio-Donahue Christine A; Ohlsson Rolf; Andraos Rita; Pearson Mark A; Sharov Alexei A; Longo Dan L; Ko Minoru S H; Levchenko Andre; Feinberg Andrew P
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20926-31.
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2007: Ladd-Acosta Christine; Pevsner Jonathan; Sabunciyan Sarven; Yolken Robert H; Webster Maree J; Dinkins Tiffany; Callinan Pauline A; Fan Jian-Bing; Potash James B; Feinberg Andrew P
DNA methylation signatures within the human brain.
American journal of human genetics 2007;81(6):1304-15.
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2007: Bjornsson Hans T; Brown Lindsey J; Fallin M Danielle; Rongione Michael A; Bibikova Marina; Wickham Eliza; Fan Jian-Bing; Feinberg Andrew P
Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors.
Journal of the National Cancer Institute 2007;99(16):1270-3.
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2007: Postovit Lynne-Marie; Costa Fabricio F; Bischof Jared M; Seftor Elisabeth A; Wen Bo; Seftor Richard E B; Feinberg Andrew P; Soares Marcelo Bento; Hendrix Mary J C
The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells.
Journal of cellular biochemistry 2007;101(4):908-17.
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2007: Feinberg Andrew P
Phenotypic plasticity and the epigenetics of human disease.
Nature 2007;447(7143):433-40.
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2007: Gosden Roger G; Feinberg Andrew P
Genetics and epigenetics--nature's pen-and-pencil set.
The New England journal of medicine 2007;356(7):731-3.
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2007: Reinhold William C; Reimers Mark A; Maunakea Alika K; Kim Sohyoung; Lababidi Samir; Scherf Uwe; Shankavaram Uma T; Ziegler Micah S; Stewart Claudia; Kouros-Mehr Hosein; Cui Hengmi; Dolginow Douglas; Scudiero Dominic A; Pommier Yves G; Munroe David J; Feinberg Andrew P; Weinstein John N
Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells.
Molecular cancer therapeutics 2007;6(2):391-403.
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2007: Rivera Miguel N; Kim Woo Jae; Wells Julie; Driscoll David R; Brannigan Brian W; Han Moonjoo; Kim James C; Feinberg Andrew P; Gerald William L; Vargas Sara O; Chin Lynda; Iafrate A John; Bell Daphne W; Haber Daniel A
An X chromosome gene, WTX, is commonly inactivated in Wilms tumor.
Science (New York, N.Y.) 2007;315(5812):642-5.
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2007: Feinberg Andrew P
An epigenetic approach to cancer etiology.
Cancer journal (Sudbury, Mass.) 2007;13(1):70-4.
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2006: Callinan Pauline A; Feinberg Andrew P
The emerging science of epigenomics.
Human molecular genetics 2006;15 Spec No 1():R95-101.
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2006: Feinberg Andrew P; Ohlsson Rolf; Henikoff Steven
The epigenetic progenitor origin of human cancer.
Nature reviews. Genetics 2006;7(1):21-33.
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2005: Kaneda Atsushi; Feinberg Andrew P
Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk.
Cancer research 2005;65(24):11236-40.
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2005: Niemitz Emily L; Feinberg Andrew P; Brandenburg Sheri A; Grundy Paul E; DeBaun Michael R
Children with idiopathic hemihypertrophy and beckwith-wiedemann syndrome have different constitutional epigenotypes associated with wilms tumor.
American journal of human genetics 2005;77(5):887-91.
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2005: Feinberg Andrew P
Cancer epigenetics is no Mickey Mouse.
Cancer cell 2005;8(4):267-8.
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2005: Wangler Michael F; An Ping; Feinberg Andrew P; Province Michael; Debaun Michael R
Inheritance pattern of Beckwith-Wiedemann syndrome is heterogeneous in 291 families with an affected proband.
American journal of medical genetics. Part A 2005;137(1):16-21.
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2005: Mummert Stephanie K; Lobanenkov Victor A; Feinberg Andrew P
Association of chromosome arm 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor.
Genes, chromosomes & cancer 2005;43(2):155-61.
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2005: Wangler Michael F; Chang Aimee S; Moley Kelle H; Feinberg Andrew P; Debaun Michael R
Factors associated with preterm delivery in mothers of children with Beckwith-Wiedemann syndrome: a case cohort study from the BWS registry.
American journal of medical genetics. Part A 2005;134A(2):187-91.
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2005: Sakatani Takashi; Kaneda Atsushi; Iacobuzio-Donahue Christine A; Carter Mark G; de Boom Witzel Sten; Okano Hideyuki; Ko Minoru S H; Ohlsson Rolf; Longo Dan L; Feinberg Andrew P
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice.
Science (New York, N.Y.) 2005;307(5717):1976-8.
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2005: Chang Aimee S; Moley Kelle H; Wangler Michael; Feinberg Andrew P; Debaun Michael R
Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients.
Fertility and sterility 2005;83(2):349-54.
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2005: Feinberg A P
A genetic approach to cancer epigenetics.
Cold Spring Harbor symposia on quantitative biology 2005;70():335-41.
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2004: Feinberg Andrew P
The epigenetics of cancer etiology.
Seminars in cancer biology 2004;14(6):427-32.
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2004: Niemitz Emily L; DeBaun Michael R; Fallon Jonathan; Murakami Kazuhiro; Kugoh Hiroyuki; Oshimura Mitsuo; Feinberg Andrew P
Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome.
American journal of human genetics 2004;75(5):844-9.
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2004: Gius David; Cui Hengmi; Bradbury C Matthew; Cook John; Smart Deedee K; Zhao Shuping; Young Lynn; Brandenburg Sheri A; Hu Yali; Bisht Kheem S; Ho Allen S; Mattson David; Sun Lunching; Munson Peter J; Chuang Eric Y; Mitchell James B; Feinberg Andrew P
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.
Cancer cell 2004;6(4):361-71.
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2004: Yu Wenqiang; Ginjala Vasudeva; Pant Vinod; Chernukhin Igor; Whitehead Joanne; Docquier France; Farrar Dawn; Tavoosidana Gholamreza; Mukhopadhyay Rituparna; Kanduri Chandrasekhar; Oshimura Mitsuo; Feinberg Andrew P; Lobanenkov Victor; Klenova Elena; Ohlsson Rolf
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.
Nature genetics 2004;36(10):1105-10.
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2004: Bjornsson Hans T; Fallin M Daniele; Feinberg Andrew P
An integrated epigenetic and genetic approach to common human disease.
Trends in genetics : TIG 2004;20(8):350-8.
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2004: Cruz-Correa Marcia; Cui Hengmi; Giardiello Francis M; Powe Neil R; Hylind Linda; Robinson Angela; Hutcheon David F; Kafonek David R; Brandenburg Sheri; Wu Yiqian; He Xiaobing; Feinberg Andrew P
Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition.
Gastroenterology 2004;126(4):964-70.
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2004: Niemitz Emily L; Feinberg Andrew P
Epigenetics and assisted reproductive technology: a call for investigation.
American journal of human genetics 2004;74(4):599-609.
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2004: Feinberg Andrew P; Tycko Benjamin
The history of cancer epigenetics.
Nature reviews. Cancer 2004;4(2):143-53.
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2004: Bjornsson H T; Cui H; Gius D; Fallin M D; Feinberg A P
The new field of epigenomics: implications for cancer and other common disease research.
Cold Spring Harbor symposia on quantitative biology 2004;69():447-56.
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2003: Kraggerud Sigrid M; Lee Maxwell P; Skotheim Rolf I; Stenwig Anna E; Fosså Sophie D; Feinberg Andrew P; Lothe Ragnhild A
Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors.
Cancer genetics and cytogenetics 2003;147(1):1-8.
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2003: Cui Hengmi; Cruz-Correa Marcia; Giardiello Francis M; Hutcheon David F; Kafonek David R; Brandenburg Sheri; Wu Yiqian; He Xiaobing; Powe Neil R; Feinberg Andrew P
Loss of IGF2 imprinting: a potential marker of colorectal cancer risk.
Science (New York, N.Y.) 2003;299(5613):1753-5.
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2003: Jouvenot Y; Ginjala V; Zhang L; Liu P-Q; Oshimura M; Feinberg A P; Wolffe A P; Ohlsson Rolf; Gregory P D
Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors.
Gene therapy 2003;10(6):513-22.
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2003: DeBaun Michael R; Niemitz Emily L; Feinberg Andrew P
Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19.
American journal of human genetics 2003;72(1):156-60.
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2003: Feinberg Andrew P; Williams Bryan R G
Wilms' tumor as a model for cancer biology.
Methods in molecular biology (Clifton, N.J.) 2003;222():239-48.
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2003: Ohlsson Rolf; Kanduri Chandrasekhar; Whitehead Joanne; Pfeifer Susan; Lobanenkov Victor; Feinberg Andrew P
Epigenetic variability and the evolution of human cancer.
Advances in cancer research 2003;88():145-68.
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2002: Feinberg Andrew P; Oshimura Mitsuo; Barrett J Carl
Epigenetic mechanisms in human disease.
Cancer research 2002;62(22):6784-7.
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2002: Cui Hengmi; Onyango Patrick; Brandenburg Sheri; Wu Yiqian; Hsieh Chih-Lin; Feinberg Andrew P
Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2.
Cancer research 2002;62(22):6442-6.
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2002: Onyango Patrick; Celic Ivana; McCaffery J Michael; Boeke Jef D; Feinberg Andrew P
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13653-8.
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2002: Feinberg Andrew P; Cui Hengmi; Ohlsson Rolf
DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms.
Seminars in cancer biology 2002;12(5):389-98.
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2002: Onyango Patrick; Jiang Shan; Uejima Hiroshi; Shamblott Michael J; Gearhart John D; Cui Hengmi; Feinberg Andrew P
Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10599-604.
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2002: Loukinov Dmitri I; Pugacheva Elena; Vatolin Sergei; Pack Svetlana D; Moon Hanlim; Chernukhin Igor; Mannan Poonam; Larsson Erik; Kanduri Chandrasekhar; Vostrov Alexander A; Cui Hengmi; Niemitz Emily L; Rasko John E J; Docquier France M; Kistler Malathi; Breen Joseph J; Zhuang Zhengping; Quitschke Wolfgang W; Renkawitz Rainer; Klenova Elena M; Feinberg Andrew P; Ohlsson Rolf; Morse Herbert C; Lobanenkov Victor V
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6806-11.
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2002: Rhee Ina; Bachman Kurtis E; Park Ben Ho; Jair Kam-Wing; Yen Ray-Whay Chiu; Schuebel Kornel E; Cui Hengmi; Feinberg Andrew P; Lengauer Christoph; Kinzler Kenneth W; Baylin Stephen B; Vogelstein Bert
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Nature 2002;416(6880):552-6.
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2002: Strichman-Almashanu Liora Z; Lee Richard S; Onyango Patrick O; Perlman Elizabeth; Flam Folke; Frieman Matthew B; Feinberg Andrew P
A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes.
Genome research 2002;12(4):543-54.
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2002: DeBaun Michael R; Niemitz Emily L; McNeil D Elizabeth; Brandenburg Sheri A; Lee Maxwell P; Feinberg Andrew P
Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects.
American journal of human genetics 2002;70(3):604-11.
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2002: Filippova Galina N; Qi Chen-Feng; Ulmer Jonathan E; Moore James M; Ward Michael D; Hu Ying J; Loukinov Dmitri I; Pugacheva Elena M; Klenova Elena M; Grundy Paul E; Feinberg Andrew P; Cleton-Jansen Anne-Marie; Moerland Elna W; Cornelisse Cees J; Suzuki Hiroyoshi; Komiya Akira; Lindblom Annika; Dorion-Bonnet Françoise; Neiman Paul E; Morse Herbert C; Collins Steven J; Lobanenkov Victor V
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity.
Cancer research 2002;62(1):48-52.
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2001: Ravenel J D; Broman K W; Perlman E J; Niemitz E L; Jayawardena T M; Bell D W; Haber D A; Uejima H; Feinberg A P
Loss of imprinting of insulin-like growth factor-II (IGF2) gene in distinguishing specific biologic subtypes of Wilms tumor.
Journal of the National Cancer Institute 2001;93(22):1698-703.
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2001: Cui H; Niemitz E L; Ravenel J D; Onyango P; Brandenburg S A; Lobanenkov V V; Feinberg A P
Loss of imprinting of insulin-like growth factor-II in Wilms' tumor commonly involves altered methylation but not mutations of CTCF or its binding site.
Cancer research 2001;61(13):4947-50.
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2001: Feinberg A P
Cancer epigenetics takes center stage.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(2):392-4.
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2001: Feinberg A P
Methylation meets genomics.
Nature genetics 2001;27(1):9-10.
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2000: Lee M P; Ravenel J D; Hu R J; Lustig L R; Tomaselli G; Berger R D; Brandenburg S A; Litzi T J; Bunton T E; Limb C; Francis H; Gorelikow M; Gu H; Washington K; Argani P; Goldenring J R; Coffey R J; Feinberg A P
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice.
The Journal of clinical investigation 2000;106(12):1447-55.
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2000: Onyango P; Miller W; Lehoczky J; Leung C T; Birren B; Wheelan S; Dewar K; Feinberg A P
Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain.
Genome research 2000;10(11):1697-710.
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2000: Feinberg A P
The two-domain hypothesis in Beckwith-Wiedemann syndrome.
The Journal of clinical investigation 2000;106(6):739-40.
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2000: Uejima H; Lee M P; Cui H; Feinberg A P
Hot-stop PCR: a simple and general assay for linear quantitation of allele ratios.
Nature genetics 2000;25(4):375-6.
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2000: Krasner A; Wallace L; Thiagalingam A; Jones C; Lengauer C; Minahan L; Ma Y; Kalikin L; Feinberg A P; Jabs E W; Tunnacliffe A; Baylin S B; Ball D W; Nelkin B D
Cloning and chromosomal localization of the human BARX2 homeobox protein gene.
Gene 2000;250(1-2):171-80.
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2000: Alders M; Ryan A; Hodges M; Bliek J; Feinberg A P; Privitera O; Westerveld A; Little P F; Mannens M
Disruption of a novel imprinted zinc-finger gene, ZNF215, in Beckwith-Wiedemann syndrome.
American journal of human genetics 2000;66(5):1473-84.
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2000: Feinberg A P
DNA methylation, genomic imprinting and cancer.
Current topics in microbiology and immunology 2000;249():87-99.
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1999: Ohlsson R; Cui H; He L; Pfeifer S; Malmikumpu H; Jiang S; Feinberg A P; Hedborg F
Mosaic allelic insulin-like growth factor 2 expression patterns reveal a link between Wilms' tumorigenesis and epigenetic heterogeneity.
Cancer research 1999;59(16):3889-92.
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1999: Mitsuya K; Meguro M; Lee M P; Katoh M; Schulz T C; Kugoh H; Yoshida M A; Niikawa N; Feinberg A P; Oshimura M
LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids.
Human molecular genetics 1999;8(7):1209-17.
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1999: Lee M P; DeBaun M R; Mitsuya K; Galonek H L; Brandenburg S; Oshimura M; Feinberg A P
Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5203-8.
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1999: Feinberg A P
Imprinting of a genomic domain of 11p15 and loss of imprinting in cancer: an introduction.
Cancer research 1999;59(7 Suppl):1743s-1746s.
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1999: Lee M P; Brandenburg S; Landes G M; Adams M; Miller G; Feinberg A P
Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting.
Human molecular genetics 1999;8(4):683-90.
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1999: Feinberg A P
Mendel stayed home. Genomic imprinting and environmental disease susceptibility, National Institute of Environmental Health Sciences and Duke University Medical Center, Durham, NC, USA, 8-10 October 1998.
Trends in genetics : TIG 1999;15(2):46.
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1998: Cui H; Horon I L; Ohlsson R; Hamilton S R; Feinberg A P
Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability.
Nature medicine 1998;4(11):1276-80.
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1998: Jiang S; Hemann M A; Lee M P; Feinberg A P
Strain-dependent developmental relaxation of imprinting of an endogenous mouse gene, Kvlqt1.
Genomics 1998;53(3):395-9.
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1998: Lee M P; Reeves C; Schmitt A; Su K; Connors T D; Hu R J; Brandenburg S; Lee M J; Miller G; Feinberg A P
Somatic mutation of TSSC5, a novel imprinted gene from human chromosome 11p15.5.
Cancer research 1998;58(18):4155-9.
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1998: Randhawa G S; Bell D W; Testa J R; Feinberg A P
Identification and mapping of human histone acetylation modifier gene homologues.
Genomics 1998;51(2):262-9.
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1998: Paulsen M; Davies K R; Bowden L M; Villar A J; Franck O; Fuermann M; Dean W L; Moore T F; Rodrigues N; Davies K E; Hu R J; Feinberg A P; Maher E R; Reik W; Walter J
Syntenic organization of the mouse distal chromosome 7 imprinting cluster and the Beckwith-Wiedemann syndrome region in chromosome 11p15.5.
Human molecular genetics 1998;7(7):1149-59.
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1998: Randhawa G S; Cui H; Barletta J A; Strichman-Almashanu L Z; Talpaz M; Kantarjian H; Deisseroth A B; Champlin R C; Feinberg A P
Loss of imprinting in disease progression in chronic myelogenous leukemia.
Blood 1998;91(9):3144-7.
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1998: Lee M P; Feinberg A P
Genomic imprinting of a human apoptosis gene homologue, TSSC3.
Cancer research 1998;58(5):1052-6.
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1997: Hu R J; Lee M P; Connors T D; Johnson L A; Burn T C; Su K; Landes G M; Feinberg A P
A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes.
Genomics 1997;46(1):9-17.
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1997: Lee M P; DeBaun M; Randhawa G; Reichard B A; Elledge S J; Feinberg A P
Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome.
American journal of human genetics 1997;61(2):304-9.
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1997: Lee M P; Feinberg A P
Aberrant splicing but not mutations of TSG101 in human breast cancer.
Cancer research 1997;57(15):3131-4.
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1997: Cost G J; Thompson J S; Reichard B A; Lee J Y; Feinberg A P
Lack of imprinting of three human cyclin-dependent kinase inhibitor genes.
Cancer research 1997;57(5):926-9.
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1997: Lee M P; Hu R J; Johnson L A; Feinberg A P
Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements.
Nature genetics 1997;15(2):181-5.
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1997: Barletta J M; Rainier S; Feinberg A P
Reversal of loss of imprinting in tumor cells by 5-aza-2'-deoxycytidine.
Cancer research 1997;57(1):48-50.
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1997: Koi M; Lamb P W; Filatov L; Feinberg A P; Barrett J C
Construction of chicken x human microcell hybrids for human gene targeting.
Cytogenetics and cell genetics 1997;76(1-2):72-6.
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1996: Thompson J S; Reese K J; DeBaun M R; Perlman E J; Feinberg A P
Reduced expression of the cyclin-dependent kinase inhibitor gene p57KIP2 in Wilms' tumor.
Cancer research 1996;56(24):5723-7.
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1996: Hu R J; Lee M P; Johnson L A; Feinberg A P
A novel human homologue of yeast nucleosome assembly protein, 65 kb centromeric to the p57KIP2 gene, is biallelically expressed in fetal and adult tissues.
Human molecular genetics 1996;5(11):1743-8.
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1996: Feinberg A P
Multiple genetic abnormalities of 11p15 in Wilms' tumor.
Medical and pediatric oncology 1996;27(5):484-9.
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1996: Lee P J; Washer L L; Law D J; Boland C R; Horon I L; Feinberg A P
Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10366-70.
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1996: Choi Y C; Gu W; Hecht N B; Feinberg A P; Chae C B
Molecular cloning of mouse somatic and testis-specific H2B histone genes containing a methylated CpG island.
DNA and cell biology 1996;15(6):495-504.
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1996: Matsuoka S; Thompson J S; Edwards M C; Bartletta J M; Grundy P; Kalikin L M; Harper J W; Elledge S J; Feinberg A P
Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):3026-30.
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1996: Nakamura T; Largaespada D A; Lee M P; Johnson L A; Ohyashiki K; Toyama K; Chen S J; Willman C L; Chen I M; Feinberg A P; Jenkins N A; Copeland N G; Shaughnessy J D
Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia.
Nature genetics 1996;12(2):154-8.
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1995: Hoovers J M; Kalikin L M; Johnson L A; Alders M; Redeker B; Law D J; Bliek J; Steenman M; Benedict M; Wiegant J; Lengauer C; Taillon-Miller P; Schlessinger D; Edwards M C; Elledge S J; Ivens A; Westerveld A; Little P; Mannens M; Feinberg A P
Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12456-60.
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1995: Boland C R; Sato J; Appelman H D; Bresalier R S; Feinberg A P
Microallelotyping defines the sequence and tempo of allelic losses at tumour suppressor gene loci during colorectal cancer progression.
Nature medicine 1995;1(9):902-9.
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1995: Rainier S; Dobry C J; Feinberg A P
Loss of imprinting in hepatoblastoma.
Cancer research 1995;55(9):1836-8.
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1995: Feinberg A P; Rainier S; DeBaun M R
Genomic imprinting, DNA methylation, and cancer.
Journal of the National Cancer Institute. Monographs 1995;(17):21-6.
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1994: Steenman M J; Rainier S; Dobry C J; Grundy P; Horon I L; Feinberg A P
Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour.
Nature genetics 1994;7(3):433-9.
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1994: Rainier S; Feinberg A P
Genomic imprinting, DNA methylation, and cancer.
Journal of the National Cancer Institute 1994;86(10):753-9.
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1994: Lee J Y; Koi M; Stanbridge E J; Oshimura M; Kumamoto A T; Feinberg A P
Simple purification of human chromosomes to homogeneity using muntjac hybrid cells.
Nature genetics 1994;7(1):29-33.
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1994: Ranier S; Dobry C J; Feinberg A P
Transcribed dinucleotide repeat polymorphism in the IGF2 gene.
Human molecular genetics 1994;3(2):386.
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1994: Mannens M; Hoovers J M; Redeker E; Verjaal M; Feinberg A P; Little P; Boavida M; Coad N; Steenman M; Bliek J
Parental imprinting of human chromosome region 11p15.3-pter involved in the Beckwith-Wiedemann syndrome and various human neoplasia.
European journal of human genetics : EJHG 1994;2(1):3-23.
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1994: Feinberg A P
A developmental context for multiple genetic alterations in Wilms' tumor.
Journal of cell science. Supplement 1994;18():7-12.
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1994: Bestor T H; Chandler V L; Feinberg A P
Epigenetic effects in eukaryotic gene expression.
Developmental genetics 1994;15(6):458-62.
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1994: Feinberg A P; Kalikin L M; Johnson L A; Thompson J S
Loss of imprinting in human cancer.
Cold Spring Harbor symposia on quantitative biology 1994;59():357-64.
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1993: Feinberg A P
Genomic imprinting and gene activation in cancer.
Nature genetics 1993;4(2):110-3.
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1993: Koi M; Johnson L A; Kalikin L M; Little P F; Nakamura Y; Feinberg A P
Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11.
Science (New York, N.Y.) 1993;260(5106):361-4.
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1993: Rainier S; Johnson L A; Dobry C J; Ping A J; Grundy P E; Feinberg A P
Relaxation of imprinted genes in human cancer.
Nature 1993;362(6422):747-9.
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1992: Feinberg A P; Johnson L A; Law D J; Kuehn S E; Steenman M; Williams B R; Thomas G; Boland C R; Rainier S; Koi M
Multiple tumor suppressor genes in multistep carcinogenesis.
The Tohoku journal of experimental medicine 1992;168(2):149-52.
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1992: Koi M; Johnson L A; Feinberg A P
A novel general strategy for cloning tumor suppressor genes using radiation-reduced chromosomal superfragments.
The Tohoku journal of experimental medicine 1992;168(2):167-8.
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1992: Maw M A; Grundy P E; Millow L J; Eccles M R; Dunn R S; Smith P J; Feinberg A P; Law D J; Paterson M C; Telzerow P E
A third Wilms' tumor locus on chromosome 16q.
Cancer research 1992;52(11):3094-8.
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1991: Upadhyaya G; Guba S C; Sih S A; Feinberg A P; Talpaz M; Kantarjian H M; Deisseroth A B; Emerson S G
Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells.
The Journal of clinical investigation 1991;88(6):2131-6.
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1991: Claxton D; Suh S P; Filaccio M; Ellerson D; Gaozza E; Andersson B; Brenner M; Reading C; Feinberg A; Moen R
Molecular analysis of retroviral transduction in chronic myelogenous leukemia.
Human gene therapy 1991;2(4):317-21.
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1990: Huang A; Campbell C E; Bonetta L; McAndrews-Hill M S; Chilton-MacNeill S; Coppes M J; Law D J; Feinberg A P; Yeger H; Williams B R
Tissue, developmental, and tumor-specific expression of divergent transcripts in Wilms tumor.
Science (New York, N.Y.) 1990;250(4983):991-4.
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1989: Delattre O; Olschwang S; Law D J; Melot T; Remvikos Y; Salmon R J; Sastre X; Validire P; Feinberg A P; Thomas G
Multiple genetic alterations in distal and proximal colorectal cancer.
Lancet 1989;2(8659):353-6.
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1989: Ping A J; Reeve A E; Law D J; Young M R; Boehnke M; Feinberg A P
Genetic linkage of Beckwith-Wiedemann syndrome to 11p15.
American journal of human genetics 1989;44(5):720-3.
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1989: Reeve A E; Sih S A; Raizis A M; Feinberg A P
Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.
Molecular and cellular biology 1989;9(4):1799-803.
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1988: Rainier S; Feinberg A P
Capture and characterization of 5-aza-2'-deoxycytidine-treated C3H/10T1/2 cells prior to transformation.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6384-8.
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1988: Law D J; Olschwang S; Monpezat J P; Lefrançois D; Jagelman D; Petrelli N J; Thomas G; Feinberg A P
Concerted nonsyntenic allelic loss in human colorectal carcinoma.
Science (New York, N.Y.) 1988;241(4868):961-5.
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1988: Feinberg A P; Gehrke C W; Kuo K C; Ehrlich M
Reduced genomic 5-methylcytosine content in human colonic neoplasia.
Cancer research 1988;48(5):1159-61.
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1988: Feinberg A P
Alterations in DNA methylation in colorectal polyps and cancer.
Progress in clinical and biological research 1988;279():309-17.
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1987: Feinberg A P; Vogelstein B
Alterations in DNA methylation in human colon neoplasia.
Seminars in surgical oncology 1987;3(3):149-51.
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1986: Trent J; Meltzer P; Rosenblum M; Harsh G; Kinzler K; Mashal R; Feinberg A; Vogelstein B
Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(2):470-3.
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1985: Fearon E R; Feinberg A P; Hamilton S H; Vogelstein B
Loss of genes on the short arm of chromosome 11 in bladder cancer.
Nature 1985;318(6044):377-80.
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1985: Feinberg A; Leyland-Jones B; Fanucchi M P; Hancock C; Fox J J; Watanabe K A; Vidal P M; Williams L; Young C W; Philips F S
Biotransformation and elimination of [2-14C]-1-(2-deoxy-2'-fluoro-beta-D -arabinofuranosyl)-5-iodocytosine in immunosuppressed patients with herpesvirus infections.
Antimicrobial agents and chemotherapy 1985;27(5):733-8.
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1985: Goelz S E; Vogelstein B; Hamilton S R; Feinberg A P
Hypomethylation of DNA from benign and malignant human colon neoplasms.
Science (New York, N.Y.) 1985;228(4696):187-90.
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1985: Vogelstein B; Fearon E R; Hamilton S R; Feinberg A P
Use of restriction fragment length polymorphisms to determine the clonal origin of human tumors.
Science (New York, N.Y.) 1985;227(4687):642-5.
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1985: Feinberg A P
The molecular biology of human cancer.
Progress in clinical and biological research 1985;198():279-92.
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1984: Feinberg A; Vidal P M; Fox J J; Watanabe K A; Chun M W; Field F H; Bencsath A; Chait B; Philips F S
Structures of metabolites isolated from urine of mice treated with the antiviral agent, 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-methyluracil.
Drug metabolism and disposition: the biological fate of chemicals 1984;12(6):784-6.
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1984: Chou T C; Lopez C; Colacino J M; Feinberg A; Watanabe K A; Fox J J; Philips F S
Metabolic competition studies of 2'-fluoro-5-iodo-1-beta-d-arabinofuranosylcytosine in vero cells and herpes simplex type 1-infected vero cells.
Molecular pharmacology 1984;26(3):587-93.
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1984: Samuels L L; Feinberg A; Moccio D M; Sirotnak F M; Rosen G
Detection by high-performance liquid chromatography of methotrexate and its metabolites in tumor tissue from osteosarcoma patients treated with high-dose methotrexate/leucovorin rescue.
Biochemical pharmacology 1984;33(17):2711-4.
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1984: Fearon E R; Vogelstein B; Feinberg A P
Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours.
Nature 1984;309(5964):176-8.
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1984: Feinberg A P; Vogelstein B
"A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.
Analytical biochemistry 1984;137(1):266-7.
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1983: Philips F S; Feinberg A; Chou T C; Vidal P M; Su T L; Watanabe K A; Fox J J
Distribution, metabolism, and excretion of 1-(2-fluoro-2-deoxy-beta-D- arabinofuranosyl)thymine and 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5- iodocytosine.
Cancer research 1983;43(8):3619-27.
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1983: Feinberg A P; Vogelstein B
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
Analytical biochemistry 1983;132(1):6-13.
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1983: Chou T C; Schmid F A; Feinberg A; Philips F S; Han J
Uptake, initial effects, and chemotherapeutic efficacy of harringtonine in murine leukemic cells sensitive and resistant to vincristine and other chemotherapeutic agents.
Cancer research 1983;43(7):3074-9.
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1983: Feinberg A P; Vogelstein B; Droller M J; Baylin S B; Nelkin B D
Mutation affecting the 12th amino acid of the c-Ha-ras oncogene product occurs infrequently in human cancer.
Science (New York, N.Y.) 1983;220(4602):1175-7.
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1983: Feinberg A P; Vogelstein B
Hypomethylation of ras oncogenes in primary human cancers.
Biochemical and biophysical research communications 1983;111(1):47-54.
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1983: Feinberg A P; Vogelstein B
Hypomethylation distinguishes genes of some human cancers from their normal counterparts.
Nature 1983;301(5895):89-92.
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1982: Feinberg A P; Coffey D S
Organ site specificity for cancer in chromosomal instability disorders.
Cancer research 1982;42(8):3252-4.
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1982: Grant A J; Feinberg A; Chou T C; Watanabe K A; Fox J J; Philips F S
Incorporation of metabolites of 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine into deoxyribonucleic acid of neoplastic and normal mammalian tissues.
Biochemical pharmacology 1982;31(6):1103-8.
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1981: Chou T C; Feinberg A; Grant A J; Vidal P; Reichman U; Watanabe K A; Fox J J; Philips F S
Pharmacological disposition and metabolic fate of 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mice and rats.
Cancer research 1981;41(9 Pt 1):3336-42.
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1980: Feinberg A; Zedeck M S
Production of a highly reactive alkylating agent from the organospecific carcinogen methylazoxymethanol by alcohol dehydrogenase.
Cancer research 1980;40(12):4446-50.
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1979: Feinberg A P; Springer W R; Barondes S H
Segregation of pre-stalk and pre-spore cells of Dictyostelium discoideum: observations consistent with selective cell cohesion.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(8):3977-81.
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1977: Feinberg A P; Leahy W R
Infantile spasms: case report of sex-linked inheritance.
Developmental medicine and child neurology 1977;19(4):524-6.
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1976: Feinberg A P; Creese I; Snyder S H
The opiate receptor: a model explaining structure-activity relationships of opiate agonists and antagonists.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(11):4215-9.
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1976: Creese I; Feinberg A P; Snyder S H
Butyrophenone influences on the opiate receptor.
European journal of pharmacology 1976;36(1):231-5.
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1975: Feinberg A P; Snyder S H
Phenothiazine drugs: structure-activity relationships explained by a conformation that mimics dopamine.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(5):1899-903.
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