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Brunhilde Felding-Habermann

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Antonio F Santidrian; Byoung B Seo; Takao Yagi; Laurie J Gay; Sarah E LeBoeuf; Akemi Matsuno-Yagi; Melissa Ritland; Brunhilde Felding-Habermann
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.
Jun Y Axup; Krishna M Bajjuri; Sandra L Biroc; Brunhilde Felding-Habermann; Jane S Forsyth; Ramesh C Halder; Benjamin M Hutchins; Stephanie A Kazane; Chan Hyuk Kim; Yingchun Lu; Jason K Pinkstaff; Melissa Ritland; Antonio F Santidrian; Aaron J Seller; Subhash C Sinha; Vaughn Smider; Karin Stafin; Aga Szydlik; Feng Tian; Hon Tran; Peter G Schultz
Synthesis of site-specific antibody-drug conjugates using unnatural amino acids.
Laurie J Gay; Brunhilde Felding-Habermann
Platelets alter tumor cell attributes to propel metastasis: programming in transit.

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2013: Antonio F Santidrian; Byoung B Seo; Takao Yagi; Laurie J Gay; Sarah E LeBoeuf; Akemi Matsuno-Yagi; Melissa Ritland; Brunhilde Felding-Habermann
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.
The Journal of clinical investigation 2013;123(3):1068-81.
2012: Jun Y Axup; Krishna M Bajjuri; Sandra L Biroc; Brunhilde Felding-Habermann; Jane S Forsyth; Ramesh C Halder; Benjamin M Hutchins; Stephanie A Kazane; Chan Hyuk Kim; Yingchun Lu; Jason K Pinkstaff; Melissa Ritland; Antonio F Santidrian; Aaron J Seller; Subhash C Sinha; Vaughn Smider; Karin Stafin; Aga Szydlik; Feng Tian; Hon Tran; Peter G Schultz
Synthesis of site-specific antibody-drug conjugates using unnatural amino acids.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(40):16101-6.
2011: Laurie J Gay; Brunhilde Felding-Habermann
Platelets alter tumor cell attributes to propel metastasis: programming in transit.
Cancer cell 2011;20(5):553-4.
2011: Mihaela Lorger; J S Forsyth; H Lee; Brunhilde Felding-Habermann
Comparison of in vitro and in vivo approaches to studying brain colonization by breast cancer cells.
Journal of neuro-oncology 2011;104(3):689-96.
2011: Rajib K Goswami; Wolf Hassenpflug; Zheng-Zheng Huang; Richard A Lerner; Krishna M Bajjuri; Sanjib Das; Brunhilde Felding-Habermann; Jane S Forsyth; Subhash C Sinha
Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro.
Bioconjugate chemistry 2011;22(8):1535-44.
2011: Benjamin M Hutchins; Stephanie A Kazane; Karin Staflin; Jane S Forsyth; Brunhilde Felding-Habermann; Vaughn V Smider; Peter G Schultz
Selective formation of covalent protein heterodimers with an unnatural amino acid.
Chemistry & biology 2011;18(3):299-303.
2011: Benjamin M Hutchins; Stephanie A Kazane; Karin Staflin; Jane S Forsyth; Brunhilde Felding-Habermann; Peter G Schultz; Vaughn Smider
Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids.
Journal of molecular biology 2011;406(4):595-603.
2011: Laurie J Gay; Brunhilde Felding-Habermann
Contribution of platelets to tumour metastasis.
Nature reviews. Cancer 2011;11(2):123-34.
2010: Mihaela Lorger; Brunhilde Felding-Habermann
Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis.
The American journal of pathology 2010;176(6):2958-71.
2010: Karin Staflin; Joseph S Krueger; Janna Hachmann; Jane S Forsyth; Mihaela Lorger; Sebastian C J Steiniger; Jenny Mee; Cristina Pop; Guy S Salvesen; Kim D Janda; Brunhilde Felding-Habermann
Targeting activated integrin alphavbeta3 with patient-derived antibodies impacts late-stage multiorgan metastasis.
Clinical & experimental metastasis 2010;27(4):217-31.
2010: Heiko Wurdak; Shoutian Zhu; Angelica Romero; Mihaela Lorger; James Watson; Chih-Yuan Chiang; Jay Zhang; Vanita S Natu; Luke L Lairson; John R Walker; Christopher M Trussell; Griffith R Harsh; Hannes Vogel; Brunhilde Felding-Habermann; Anthony P Orth; Loren J Miraglia; Daniel R Rines; Stephen L Skirboll; Peter G Schultz
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.
Cell stem cell 2010;6(1):37-47.
2009: Rajib Kumar Goswami; Zheng-Zheng Huang; Jane S Forsyth; Brunhilde Felding-Habermann; Subhash C Sinha
Multiple catalytic aldolase antibodies suitable for chemical programming.
Bioorganic & medicinal chemistry letters 2009;19(14):3821-4.
2009: Mihaela Lorger; Joseph S Krueger; Melissa O'Neal; Karin Staflin; Brunhilde Felding-Habermann
Activation of tumor cell integrin alphavbeta3 controls angiogenesis and metastatic growth in the brain.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10666-71.
2009: Jennifer Katz; Joseph Krueger; Brunhilde Felding-Habermann; Evan Y Snyder
Maintaining and engineering neural stem cells for delivery of genetically encoded therapy to brain tumors.
Methods in molecular biology (Clifton, N.J.) 2009;568():249-59.
2008: Henri H Versteeg; Florence Schaffner; Marjolein Kerver; Helle H Petersen; Jasimuddin Ahamed; Brunhilde Felding-Habermann; Yoshikazu Takada; Barbara M Mueller; Wolfram Ruf
Inhibition of tissue factor signaling suppresses tumor growth.
Blood 2008;111(1):190-9.
2007: Shashank Jain; Masahiko Zuka; Jungling Liu; Susan Russell; Judith Dent; José A Guerrero; Jane Forsyth; Brigid Maruszak; T Kent Gartner; Brunhilde Felding-Habermann; Jerry Ware
Platelet glycoprotein Ib alpha supports experimental lung metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):9024-8.
2007: Ying Liu; Sebastian C J Steiniger; YoungSoo Kim; Gunnar Kaufmann; Brunhilde Felding-Habermann; Kim D Janda
Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery.
Molecular pharmaceutics 2007;4(3):435-47.
2007: Diane Palmieri; Ann F Chambers; Brunhilde Felding-Habermann; Suyun Huang; Patricia S Steeg
The biology of metastasis to a sanctuary site.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(6):1656-62.
2007: Emily I Chen; Johannes Hewel; Joseph S Krueger; Claire Tiraby; Martin R Weber; Anastasia Kralli; Katja Becker; John R Yates; Brunhilde Felding-Habermann
Adaptation of energy metabolism in breast cancer brain metastases.
Cancer research 2007;67(4):1472-86.
2006: Youngsoo Kim; Antonietta Lillo; Sebastian C J Steiniger; Ying Liu; Carlo Ballatore; Andrea Anichini; Roberta Mortarini; Gunnar Kaufmann; Bin Zhou; Brunhilde Felding-Habermann; Kim D Janda
Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand.
Biochemistry 2006;45(31):9434-44.
2006: Emily I Chen; Johannes Hewel; Brunhilde Felding-Habermann; John R Yates
Large scale protein profiling by combination of protein fractionation and multidimensional protein identification technology (MudPIT).
Molecular & cellular proteomics : MCP 2006;5(1):53-6.
2005: Emily I Chen; Laurence Florens; Fumiko T Axelrod; Edward Monosov; Carlos F Barbas; John R Yates; Brunhilde Felding-Habermann; Jeffrey W Smith
Maspin alters the carcinoma proteome.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1123-4.
2004: Brunhilde Felding-Habermann; Richard A Lerner; Antonietta Lillo; Shufei Zhuang; Martin R Weber; Sandra Arrues; Changshou Gao; Shenlan Mao; Alan Saven; Kim D Janda
Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(49):17210-5.
2004: Antonietta Lillo; Chengzao Sun; Changshou Gao; Henrik J Ditzel; Jay Parrish; Carla-Marie Gauss; Jason Moss; Brunhilde Felding-Habermann; Peter Wirsching; Dale L Boger; Kim D Janda
A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents.
Chemistry & biology 2004;11(7):897-906.
2003: Melanie Rolli; Emilia Fransvea; Jan Pilch; Alan Saven; Brunhilde Felding-Habermann
Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9482-7.
2003: Brunhilde Felding-Habermann
Targeting tumor cell-platelet interaction in breast cancer metastasis.
Pathophysiology of haemostasis and thrombosis 2003;33 Suppl 1():56-8.
2003: Brunhilde Felding-Habermann
Integrin adhesion receptors in tumor metastasis.
Clinical & experimental metastasis 2003;20(3):203-13.
2002: Kyung Joo Lee; Shenlan Mao; Chengzao Sun; Changshou Gao; Ola Blixt; Sandra Arrues; Louis G Hom; Gunnar Kaufmann; Timothy Z Hoffman; Avery R Coyle; James C Paulson; Brunhilde Felding-Habermann; Kim D Janda
Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen.
Journal of the American Chemical Society 2002;124(42):12439-46.
2002: Jan Pilch; Rolf Habermann; Brunhilde Felding-Habermann
Unique ability of integrin alpha(v)beta 3 to support tumor cell arrest under dynamic flow conditions.
The Journal of biological chemistry 2002;277(24):21930-8.
2002: Brunhilde Felding-Habermann; Emilia Fransvea; Timothy E O'Toole; Lisa Manzuk; Barbara Faha; Mary Hensler
Involvement of tumor cell integrin alpha v beta 3 in hematogenous metastasis of human melanoma cells.
Clinical & experimental metastasis 2002;19(5):427-36.
2001: Brunhilde Felding-Habermann; Timothy E O'Toole; Jeffrey W Smith; Emilia Fransvea; Zaverio M Ruggeri; Mark H Ginsberg; Paul E Hughes; Nisar Pampori; Sanford J Shattil; Alan Saven; Barbara M Mueller
Integrin activation controls metastasis in human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1853-8.
2001: Brunhilde Felding-Habermann
Tumor cell-platelet interaction in metastatic disease.
Haemostasis 2001;31 Suppl 1():55-8.
1997: Brunhilde Felding-Habermann; Steven A. Silletti; F Mei; Chi-Hung Siu; PM Yip; Peter C Brooks; David A Cheresh; Timothy E O'Toole; Mark H Ginsberg; Anthony M P Montgomery
A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins.
The Journal of cell biology 1997;139(6):1567-81.
1997: Paola Lanza; Brunhilde Felding-Habermann; Zaverio M Ruggeri; Maurizio Zanetti; Rosario Billetta
Selective interaction of a conformationally-constrained Arg-Gly-Asp (RGD) motif with the integrin receptor alphavbeta3 expressed on human tumor cells.
Blood cells, molecules & diseases 1997;23(2):230-41.
1997: Thomas J Kunicki; D S Annis; Brunhilde Felding-Habermann
Molecular determinants of arg-gly-asp ligand specificity for beta3 integrins.
The Journal of biological chemistry 1997;272(7):4103-7.
1996: Brunhilde Felding-Habermann; R Habermann; Enrique Saldívar; Zaverio M Ruggeri
Role of beta3 integrins in melanoma cell adhesion to activated platelets under flow.
The Journal of biological chemistry 1996;271(10):5892-900.
1993: Brunhilde Felding-Habermann; David A Cheresh
Vitronectin and its receptors.
Current opinion in cell biology 1993;5(5):864-8.
1992: Brunhilde Felding-Habermann; Barbara M Mueller; C A Romerdahl; David A Cheresh
Involvement of integrin alpha V gene expression in human melanoma tumorigenicity.
The Journal of clinical investigation 1992;89(6):2018-22.
1992: Brunhilde Felding-Habermann; Zaverio M Ruggeri; David A Cheresh
Distinct biological consequences of integrin alpha v beta 3-mediated melanoma cell adhesion to fibrinogen and its plasmic fragments.
The Journal of biological chemistry 1992;267(8):5070-7.
1992: Luraynne C Sanders; Brunhilde Felding-Habermann; Barbara M Mueller; David A Cheresh
Role of alpha V integrins and vitronectin in human melanoma cell growth.
Cold Spring Harbor symposia on quantitative biology 1992;57():233-40.