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Michael Ferguson

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Güther Maria Lucia Sampaio; Beattie Kenneth; Lamont Douglas J; James John; Prescott Alan R; Ferguson Michael A J
Fate of glycosylphosphatidylinositol (GPI)-less procyclin and characterization of sialylated non-GPI-anchored surface coat molecules of procyclic-form Trypanosoma brucei.
Izquierdo Luis; Schulz Benjamin L; Rodrigues João A; Güther Maria Lucia S; Procter James B; Barton Geoffrey J; Aebi Markus; Ferguson Michael A J
Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases.
Nett Isabelle R E; Martin David M A; Miranda-Saavedra Diego; Lamont Douglas; Barber Jonathan D; Mehlert Angela; Ferguson Michael A J
The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sickness.

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All Publications

2009: Güther Maria Lucia Sampaio; Beattie Kenneth; Lamont Douglas J; James John; Prescott Alan R; Ferguson Michael A J
Fate of glycosylphosphatidylinositol (GPI)-less procyclin and characterization of sialylated non-GPI-anchored surface coat molecules of procyclic-form Trypanosoma brucei.
Eukaryotic cell 2009;8(9):1407-17.
2009: Izquierdo Luis; Schulz Benjamin L; Rodrigues João A; Güther Maria Lucia S; Procter James B; Barton Geoffrey J; Aebi Markus; Ferguson Michael A J
Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases.
The EMBO journal 2009;28(17):2650-61.
2009: Nett Isabelle R E; Martin David M A; Miranda-Saavedra Diego; Lamont Douglas; Barber Jonathan D; Mehlert Angela; Ferguson Michael A J
The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sickness.
Molecular & cellular proteomics : MCP 2009;8(7):1527-38.
2009: Nett Isabelle R E; Davidson Lindsay; Lamont Douglas; Ferguson Michael A J
Identification and specific localization of tyrosine-phosphorylated proteins in Trypanosoma brucei.
Eukaryotic cell 2009;8(4):617-26.
2009: Izquierdo Luis; Nakanishi Masayuki; Mehlert Angela; Machray Greg; Barton Geoffrey J; Ferguson Michael A J
Identification of a glycosylphosphatidylinositol anchor-modifying beta1-3 N-acetylglucosaminyl transferase in Trypanosoma brucei.
Molecular microbiology 2009;71(2):478-91.
2008: Urbaniak Michael D; Yashunsky Dmitry V; Crossman Arthur; Nikolaev Andrei V; Ferguson Michael A J
Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues.
ACS chemical biology 2008;3(10):625-34.
2008: Urbaniak Michael D; Crossman Arthur; Ferguson Michael A J
Probing Trypanosoma brucei glycosylphosphatidylinositol biosynthesis using novel precursor-analogues.
Chemical biology & drug design 2008;72(2):127-32.
2008: Signorell Aita; Rauch Monika; Jelk Jennifer; Ferguson Michael A J; Bütikofer Peter
Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway.
The Journal of biological chemistry 2008;283(35):23636-44.
2008: Crossman Arthur T; Urbaniak Michael D; Ferguson Michael A J
Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis.
Carbohydrate research 2008;343(9):1478-81.
2008: Stokes Matthew J; Güther M Lucia S; Turnock Daniel C; Prescott Alan R; Martin Kirstee L; Alphey Magnus S; Ferguson Michael A J
The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation.
The Journal of biological chemistry 2008;283(23):16147-61.
2008: Manthri Sujatha; Güther M Lucia S; Izquierdo Luis; Acosta-Serrano Alvaro; Ferguson Michael A J
Deletion of the TbALG3 gene demonstrates site-specific N-glycosylation and N-glycan processing in Trypanosoma brucei.
Glycobiology 2008;18(5):367-83.
2007: Turnock Daniel C; Izquierdo Luis; Ferguson Michael A J
The de novo synthesis of GDP-fucose is essential for flagellar adhesion and cell growth in Trypanosoma brucei.
The Journal of biological chemistry 2007;282(39):28853-63.
2007: Turnock Daniel C; Ferguson Michael A J
Sugar nucleotide pools of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major.
Eukaryotic cell 2007;6(8):1450-63.
2007: Mehlert Angela; Ferguson Michael A J
Structure of the glycosylphosphatidylinositol anchor of the Trypanosoma brucei transferrin receptor.
Molecular and biochemical parasitology 2007;151(2):220-3.
2006: Güther Maria Lucia Sampaio; Lee Sylvia; Tetley Laurence; Acosta-Serrano Alvaro; Ferguson Michael A J
GPI-anchored proteins and free GPI glycolipids of procyclic form Trypanosoma brucei are nonessential for growth, are required for colonization of the tsetse fly, and are not the only components of the surface coat.
Molecular biology of the cell 2006;17(12):5265-74.
2006: Urbaniak Michael D; Turnock Daniel C; Ferguson Michael A J
Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4'-epimerase conditional null mutant.
Eukaryotic cell 2006;5(11):1906-13.
2006: Urbaniak Michael D; Tabudravu Jioji N; Msaki Aichi; Matera Kathy Mansfield; Brenk Ruth; Jaspars Marcel; Ferguson Michael A J
Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.
Bioorganic & medicinal chemistry letters 2006;16(22):5744-7.
2006: Alphey Magnus S; Burton Andrew; Urbaniak Michael D; Boons Geert-Jan; Ferguson Michael A J; Hunter William N
Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 9):829-34.
2006: Priest Jeffrey W; Mehlert Angela; Moss Delynn M; Arrowood Michael J; Ferguson Michael A J
Characterization of the glycosylphosphatidylinositol anchor of the immunodominant Cryptosporidium parvum 17-kDa antigen.
Molecular and biochemical parasitology 2006;149(1):108-12.
2006: Rogers Matthew E; Sizova Olga V; Ferguson Michael A J; Nikolaev Andrei V; Bates Paul A
Synthetic glycovaccine protects against the bite of leishmania-infected sand flies.
The Journal of infectious diseases 2006;194(4):512-8.
2006: MacRae James I; Obado Samson O; Turnock Daniel C; Roper Janine R; Kierans Martin; Kelly John M; Ferguson Michael A J
The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology.
Molecular and biochemical parasitology 2006;147(1):126-36.
2006: Fyffe Stewart A; Alphey Magnus S; Buetow Lori; Smith Terry K; Ferguson Michael A J; Sørensen Morten D; Björkling Fredrik; Hunter William N
Recombinant human PPAR-beta/delta ligand-binding domain is locked in an activated conformation by endogenous fatty acids.
Journal of molecular biology 2006;356(4):1005-13.
2006: Fyffe Stewart A; Alphey Magnus S; Buetow Lori; Smith Terry K; Ferguson Michael A J; Sørensen Morten D; Björkling Fredrik; Hunter William N
Reevaluation of the PPAR-beta/delta ligand binding domain model reveals why it exhibits the activated form.
Molecular cell 2006;21(1):1-2.
2006: Yashunsky Dmitry V; Borodkin Vladimir S; Ferguson Michael A J; Nikolaev Andrei V
The chemical synthesis of bioactive glycosylphosphatidylinositols from Trypanosoma cruzi containing an unsaturated fatty acid in the lipid.
Angewandte Chemie (International ed. in English) 2006;45(3):468-74.
2006: Bates Steven; Hughes H Bleddyn; Munro Carol A; Thomas William P H; MacCallum Donna M; Bertram Gwyneth; Atrih Abdelmadjid; Ferguson Michael A J; Brown Alistair J P; Odds Frank C; Gow Neil A R
Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans.
The Journal of biological chemistry 2006;281(1):90-8.
2005: Jones Deuan C; Mehlert Angela; Güther M Lucia S; Ferguson Michael A J
Deletion of the glucosidase II gene in Trypanosoma brucei reveals novel N-glycosylation mechanisms in the biosynthesis of variant surface glycoprotein.
The Journal of biological chemistry 2005;280(43):35929-42.
2005: Urbaniak Michael D; Crossman Arthur; Chang Tunhan; Smith Terry K; van Aalten Daan M F; Ferguson Michael A J
The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme.
The Journal of biological chemistry 2005;280(24):22831-8.
2005: Roper Janine R; Güther M Lucia S; Macrae James I; Prescott Alan R; Hallyburton Irene; Acosta-Serrano Alvaro; Ferguson Michael A J
The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number.
The Journal of biological chemistry 2005;280(20):19728-36.
2005: Macrae James I; Acosta-Serrano Alvaro; Morrice Nicholas A; Mehlert Angela; Ferguson Michael A J
Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes.
The Journal of biological chemistry 2005;280(13):12201-11.
2005: Higson Adrian P; Ross Andrew J; Tsvetkov Yury E; Routier Françoise H; Sizova Olga V; Ferguson Michael A J; Nikolaev Andrei V
Synthetic fragments of antigenic lipophosphoglycans from Leishmania major and Leishmania mexicana and their use for characterisation of the Leishmania elongating alpha-D-mannopyranosylphosphate transferase.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(7):2019-30.
2005: Macrae James I; Ferguson Michael A J
A robust and selective method for the quantification of glycosylphosphatidylinositols in biological samples.
Glycobiology 2005;15(2):131-8.
2005: Kemp Lauris E; Alphey Magnus S; Bond Charles S; Ferguson Michael A J; Hecht Stefan; Bacher Adelbert; Eisenreich Wolfgang; Rohdich Felix; Hunter William N
The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 1):45-52.
2005: Munro Carol A; Bates Steven; Buurman Ed T; Hughes H Bleddyn; Maccallum Donna M; Bertram Gwyneth; Atrih Abdel; Ferguson Michael A J; Bain Judith M; Brand Alexandra; Hamilton Suzanne; Westwater Caroline; Thomson Lynn M; Brown Alistair J P; Odds Frank C; Gow Neil A R
Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence.
The Journal of biological chemistry 2005;280(2):1051-60.
2005: Atrih Abdelmadjid; Richardson Julia M; Prescott Alan R; Ferguson Michael A J
Trypanosoma brucei glycoproteins contain novel giant poly-N-acetyllactosamine carbohydrate chains.
The Journal of biological chemistry 2005;280(2):865-71.
2004: Fontaine Thierry; Smith Terry K; Crossman Arthur; Brimacombe John S; Latgé Jean-Paul; Ferguson Michael A J
In vitro biosynthesis of glycosylphosphatidylinositol in Aspergillus fumigatus.
Biochemistry 2004;43(48):15267-75.
2004: Smith Terry K; Crossman Arthur; Brimacombe John S; Ferguson Michael A J
Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness.
The EMBO journal 2004;23(23):4701-8.
2004: Jones D; Mehlert A; Ferguson M A J
The N-glycan glucosidase system in Trypanosoma brucei.
Biochemical Society transactions 2004;32(Pt 5):766-8.
2004: Rogers Matthew E; Ilg Thomas; Nikolaev Andrei V; Ferguson Michael A J; Bates Paul A
Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG.
Nature 2004;430(6998):463-7.
2004: Nagamune Kisaburo; Acosta-Serrano Alvaro; Uemura Haruki; Brun Reto; Kunz-Renggli Christina; Maeda Yusuke; Ferguson Michael A J; Kinoshita Taroh
Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors.
The Journal of experimental medicine 2004;199(10):1445-50.
2004: Dix Alexander P; Borissow Charles N; Ferguson Michael A J; Brimacombe John S
The synthesis of some deoxygenated analogues of early intermediates in the biosynthesis of glycosylphosphatidylinositol (GPI) membrane anchors.
Carbohydrate research 2004;339(7):1263-77.
2003: Güther M Lucia S; Prescott Alan R; Ferguson Michael A J
Deletion of the GPIdeAc gene alters the location and fate of glycosylphosphatidylinositol precursors in Trypanosoma brucei.
Biochemistry 2003;42(49):14532-40.
2003: Priest Jeffrey W; Mehlert Angela; Arrowood Michael J; Riggs Michael W; Ferguson Michael A J
Characterization of a low molecular weight glycolipid antigen from Cryptosporidium parvum.
The Journal of biological chemistry 2003;278(52):52212-22.
2003: Roper Janine R; Ferguson Michael A J
Cloning and characterisation of the UDP-glucose 4'-epimerase of Trypanosoma cruzi.
Molecular and biochemical parasitology 2003;132(1):47-53.
2003: Fontaine Thierry; Magnin Thierry; Melhert Angela; Lamont Douglas; Latge Jean-Paul; Ferguson Michael A J
Structures of the glycosylphosphatidylinositol membrane anchors from Aspergillus fumigatus membrane proteins.
Glycobiology 2003;13(3):169-77.
2003: Shaw Matthew P; Bond Charles S; Roper Janine R; Gourley David G; Ferguson Michael A J; Hunter William N
High-resolution crystal structure of Trypanosoma brucei UDP-galactose 4'-epimerase: a potential target for structure-based development of novel trypanocides.
Molecular and biochemical parasitology 2003;126(2):173-80.
2002: Thomson Lynn M; Lamont Douglas J; Mehlert Angela; Barry J David; Ferguson Michael A J
Partial structure of glutamic acid and alanine-rich protein, a major surface glycoprotein of the insect stages of Trypanosoma congolense.
The Journal of biological chemistry 2002;277(50):48899-904.
2002: Chang Tunhan; Milne Kenneth G; Güther Maria Lucia Sampaio; Smith Terry K; Ferguson Michael A J
Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite.
The Journal of biological chemistry 2002;277(51):50176-82.
2002: Crossman Arthur; Paterson Michael J; Ferguson Michael A J; Smith Terry K; Brimacombe John S
Further probing of the substrate specificities and inhibition of enzymes involved at an early stage of glycosylphosphatidylinositol (GPI) biosynthesis.
Carbohydrate research 2002;337(21-23):2049-59.
2002: Smith Terry K; Gerold Peter; Crossman Arthur; Paterson Michael J; Borissow Charles N; Brimacombe John S; Ferguson Michael A J; Schwarz Ralph T
Substrate specificity of the Plasmodium falciparum glycosylphosphatidylinositol biosynthetic pathway and inhibition by species-specific suicide substrates.
Biochemistry 2002;41(41):12395-406.
2002: Mehlert Angela; Bond Charles S; Ferguson Michael A J
The glycoforms of a Trypanosoma brucei variant surface glycoprotein and molecular modeling of a glycosylated surface coat.
Glycobiology 2002;12(10):607-12.
2002: Smith Terry K; Crossman Arthur; Paterson Michael J; Borissow Charles N; Brimacombe John S; Ferguson Michael A J
Specificities of enzymes of glycosylphosphatidylinositol biosynthesis in Trypanosoma brucei and HeLa cells.
The Journal of biological chemistry 2002;277(40):37147-53.
2002: Ropert Catherine; Ferreira Ludmila R P; Campos Marco A S; Procópio Daniela O; Travassos Luiz R; Ferguson Michael A J; Reis Luiz F L; Teixeira Mauro M; Almeida Igor C; Gazzinelli Ricardo T
Macrophage signaling by glycosylphosphatidylinositol-anchored mucin-like glycoproteins derived from Trypanosoma cruzi trypomastigotes.
Microbes and infection / Institut Pasteur 2002;4(9):1015-25.
2002: Roper Janine R; Guther Maria Lucia S; Milne Kenneth G; Ferguson Michael A J
Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):5884-9.
2002: Bütikofer Peter; Vassella Erik; Mehlert Angela; Ferguson Michael A J; Roditi Isabel
Characterisation and cellular localisation of a GPEET procyclin precursor in Trypanosoma brucei insect forms.
Molecular and biochemical parasitology 2002;119(1):87-95.
2001: Güther M L; Leal S; Morrice N A; Cross G A; Ferguson M A
Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei.
The EMBO journal 2001;20(17):4923-34.
2001: Smith T K; Crossman A; Borissow C N; Paterson M J; Dix A; Brimacombe J S; Ferguson M A
Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.
The EMBO journal 2001;20(13):3322-32.
2001: Milne K G; Mehlert A; Ferguson M A
The use of Pseudomonas acyl-CoA synthetase to form acyl-CoAs from dicarboxylic fatty acids.
Biochimica et biophysica acta 2001;1531(1-2):1-3.
2001: Ropert C; Almeida I C; Closel M; Travassos L R; Ferguson M A; Cohen P; Gazzinelli R T
Requirement of mitogen-activated protein kinases and I kappa B phosphorylation for induction of proinflammatory cytokines synthesis by macrophages indicates functional similarity of receptors triggered by glycosylphosphatidylinositol anchors from parasitic protozoa and bacterial lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3423-31.
2001: Milne K G; Güther M L; Ferguson M A
Acyl-CoA binding protein is essential in bloodstream form Trypanosoma brucei.
Molecular and biochemical parasitology 2001;112(2):301-4.
2000: Ferguson M A
Glycosylphosphatidylinositol biosynthesis validated as a drug target for African sleeping sickness.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(20):10673-5.
2000: Smith T K; Paterson M J; Crossman A; Brimacombe J S; Ferguson M A
Parasite-specific inhibition of the glycosylphosphatidylinositol biosynthetic pathway by stereoisomeric substrate analogues.
Biochemistry 2000;39(38):11801-7.
2000: Routier F H; Higson A P; Ivanova I A; Ross A J; Tsvetkov Y E; Yashunsky D V; Bates P A; Nikolaev A V; Ferguson M A
Characterization of the elongating alpha-D-mannosyl phosphate transferase from three species of Leishmania using synthetic acceptor substrate analogues.
Biochemistry 2000;39(27):8017-25.
2000: Milne K G; Ferguson M A
Cloning, expression, and characterization of the acyl-CoA-binding protein in African trypanosomes.
The Journal of biological chemistry 2000;275(17):12503-8.
2000: Almeida I C; Camargo M M; Procópio D O; Silva L S; Mehlert A; Travassos L R; Gazzinelli R T; Ferguson M A
Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents.
The EMBO journal 2000;19(7):1476-85.
2000: Pereira-Chioccola V L; Acosta-Serrano A; Correia de Almeida I; Ferguson M A; Souto-Padron T; Rodrigues M M; Travassos L R; Schenkman S
Mucin-like molecules form a negatively charged coat that protects Trypanosoma cruzi trypomastigotes from killing by human anti-alpha-galactosyl antibodies.
Journal of cell science 2000;113 ( Pt 7)():1299-307.
2000: Zitzmann N; Mehlert A; Carrouée S; Rudd P M; Ferguson M A;
Protein structure controls the processing of the N-linked oligosaccharides and glycosylphosphatidylinositol glycans of variant surface glycoproteins expressed in bloodstream form Trypanosoma brucei.
Glycobiology 2000;10(3):243-9.
2000: Lischke A; Klein C; Stierhof Y D; Hempel M; Mehlert A; Almeida I C; Ferguson M A; Overath P
Isolation and characterization of glycosylphosphatidylinositol-anchored, mucin-like surface glycoproteins from bloodstream forms of the freshwater-fish parasite Trypanosoma carassii.
The Biochemical journal 2000;345 Pt 3():693-700.
1999: Routier F H; Nikolaev A V; Ferguson M A
The preparation of neoglycoconjugates containing inter-saccharide phosphodiester linkages as potential anti-Leishmania vaccines.
Glycoconjugate journal 1999;16(12):773-80.
1999: Smith T K; Sharma D K; Crossman A; Brimacombe J S; Ferguson M A
Selective inhibitors of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei.
The EMBO journal 1999;18(21):5922-30.
1999: Ferguson M A; Brimacombe J S; Brown J R; Crossman A; Dix A; Field R A; Güther M L; Milne K G; Sharma D K; Smith T K
The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.
Biochimica et biophysica acta 1999;1455(2-3):327-40.
1999: Acosta-Serrano A; Cole R N; Mehlert A; Lee M G; Ferguson M A; Englund P T
The procyclin repertoire of Trypanosoma brucei. Identification and structural characterization of the Glu-Pro-rich polypeptides.
The Journal of biological chemistry 1999;274(42):29763-71.
1999: Crossman A; Brimacombe J S; Ferguson M A; Smith T K
Synthesis of some second-generation substrate analogues of early intermediates in the biosynthetic pathway of glycosylphosphatidylinositol membrane anchors.
Carbohydrate research 1999;321(1-2):42-51.
1999: Ferguson M A
The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research.
Journal of cell science 1999;112 ( Pt 17)():2799-809.
1999: Branquinha M H; Vermelho A B; Almeida I C; Mehlert A; Ferguson M A
Structural studies on the polar glycoinositol phospholipids of Trypanosoma (Schizotrypanum) dionisii from bats.
Molecular and biochemical parasitology 1999;102(1):179-89.
1999: Procópio D O; Teixeira M M; Camargo M M; Travassos L R; Ferguson M A; Almeida I C; Gazzinelli R T
Differential inhibitory mechanism of cyclic AMP on TNF-alpha and IL-12 synthesis by macrophages exposed to microbial stimuli.
British journal of pharmacology 1999;127(5):1195-205.
1999: Wilson I B; O'Donnell N; Allen S; Mehlert A; Ferguson M A
Typing of Leishmania lipophosphoglycans by electrospray mass spectrometry.
Molecular and biochemical parasitology 1999;100(2):207-15.
1999: Sharma D K; Smith T K; Weller C T; Crossman A; Brimacombe J S; Ferguson M A
Differences between the trypanosomal and human GlcNAc-PI de-N-acetylases of glycosylphosphatidylinositol membrane anchor biosynthesis.
Glycobiology 1999;9(4):415-22.
1999: Mehlert A; Treumann A; Ferguson M A
Trypanosoma brucei GPEET-PARP is phosphorylated on six out of seven threonine residues.
Molecular and biochemical parasitology 1999;98(2):291-6.
1999: Piedrafita D; Proudfoot L; Nikolaev A V; Xu D; Sands W; Feng G J; Thomas E; Brewer J; Ferguson M A; Alexander J; Liew F Y
Regulation of macrophage IL-12 synthesis by Leishmania phosphoglycans.
European journal of immunology 1999;29(1):235-44.
1999: Milne K G; Ferguson M A; Englund P T
A novel glycosylphosphatidylinositol in African trypanosomes. A possible catabolic intermediate.
The Journal of biological chemistry 1999;274(3):1465-71.
1999: Almeida I C; Gazzinelli R; Ferguson M A; Travassos L R
Trypanosoma cruzi mucins: potential functions of a complex structure.
Memórias do Instituto Oswaldo Cruz 1999;94 Suppl 1():173-6.
1998: Milne K G; Prescott A R; Ferguson M A
Transformation of monomorphic Trypanosoma brucei bloodstream form trypomastigotes into procyclic forms at 37 degrees C by removing glucose from the culture medium.
Molecular and biochemical parasitology 1998;94(1):99-112.
1998: Mehlert A; Zitzmann N; Richardson J M; Treumann A; Ferguson M A
The glycosylation of the variant surface glycoproteins and procyclic acidic repetitive proteins of Trypanosoma brucei.
Molecular and biochemical parasitology 1998;91(1):145-52.
1998: Mehlert A; Richardson J M; Ferguson M A
Structure of the glycosylphosphatidylinositol membrane anchor glycan of a class-2 variant surface glycoprotein from Trypanosoma brucei.
Journal of molecular biology 1998;277(2):379-92.
1998: Treumann A; Güther M L; Schneider P; Ferguson M A
Analysis of the carbohydrate and lipid components of glycosylphosphatidylinositol structures.
Methods in molecular biology (Clifton, N.J.) 1998;76():213-35.
1997: Richardson J M; Mehlert A; Ferguson M A
Primary and three dimensional structure of the type II VSG GPI anchor.
Biochemical Society transactions 1997;25(4):S664.
1997: Smith T K; Sharma D K; Crossman A; Dix A; Brimacombe J S; Ferguson M A
Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues.
The EMBO journal 1997;16(22):6667-75.
1997: Sharma D K; Smith T K; Crossman A; Brimacombe J S; Ferguson M A
Substrate specificity of the N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol membrane anchor biosynthesis in African trypanosomes and human cells.
The Biochemical journal 1997;328 ( Pt 1)():171-7.
1997: Ferguson M A
The surface glycoconjugates of trypanosomatid parasites.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1997;352(1359):1295-302.
1997: Smith T K; Milne F C; Sharma D K; Crossman A; Brimacombe J S; Ferguson M A
Early steps in glycosylphosphatidylinositol biosynthesis in Leishmania major.
The Biochemical journal 1997;326 ( Pt 2)():393-400.
1997: Treumann A; Zitzmann N; Hülsmeier A; Prescott A R; Almond A; Sheehan J; Ferguson M A
Structural characterisation of two forms of procyclic acidic repetitive protein expressed by procyclic forms of Trypanosoma brucei.
Journal of molecular biology 1997;269(4):529-47.
1997: Camargo M M; Almeida I C; Pereira M E; Ferguson M A; Travassos L R; Gazzinelli R T
Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):5890-901.
1997: Brown J R; Güther M L; Field R A; Ferguson M A
Hydrophobic mannosides act as acceptors for trypanosome alpha-mannosyltransferases.
Glycobiology 1997;7(4):549-58.
1997: Mehlert A; Richardson J M; Ferguson M A
The core glycosylphosphatidylinositol anchor structures of Trypanosoma brucei variant surface glycoprotein 221.
Biochemical Society transactions 1997;25(1):13S.
1997: Gazzinelli R T; Camargo M M; Almeida I C; Morita Y S; Giraldo M; Acosta-Serrano A; Hieny S; Englund P T; Ferguson M A; Travassos L R; Sher A
Identification and characterization of protozoan products that trigger the synthesis of IL-12 by inflammatory macrophages.
Chemical immunology 1997;68():136-52.
1996: Brown G M; Millar A R; Masterson C; Brimacombe J S; Nikolaev A V; Ferguson M A
Synthetic phospho-oligosaccharide fragments of lipophosphoglycan as acceptors for Leishmania major alpha-D-mannosylphosphate transferase.
European journal of biochemistry / FEBS 1996;242(2):410-6.
1996: Proudfoot L; Nikolaev A V; Feng G J; Wei W Q; Ferguson M A; Brimacombe J S; Liew F Y
Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10984-9.
1996: Almeida I C; Neville D C; Mehlert A; Treumann A; Ferguson M A; Previato J O; Travassos L R
Structure of the N-linked oligosaccharide of the main diagnostic antigen of the pathogenic fungus Paracoccidioides brasiliensis.
Glycobiology 1996;6(5):507-15.
1996: Güther M L; Treumann A; Ferguson M A
Molecular species analysis and quantification of the glycosylphosphatidylinositol intermediate glycolipid C from Trypanosoma brucei.
Molecular and biochemical parasitology 1996;77(2):137-45.
1996: Smith T K; Cottaz S; Brimacombe J S; Ferguson M A
Substrate specificity of the dolichol phosphate mannose: glucosaminyl phosphatidylinositol alpha1-4-mannosyltransferase of the glycosylphosphatidylinositol biosynthetic pathway of African trypanosomes.
The Journal of biological chemistry 1996;271(11):6476-82.
1996: Schneider P; Treumann A; Milne K G; McConville M J; Zitzmann N; Ferguson M A
Structural studies on a lipoarabinogalactan of Crithidia fasciculata.
The Biochemical journal 1996;313 ( Pt 3)():963-71.
1995: Serrano A A; Schenkman S; Yoshida N; Mehlert A; Richardson J M; Ferguson M A
The lipid structure of the glycosylphosphatidylinositol-anchored mucin-like sialic acid acceptors of Trypanosoma cruzi changes during parasite differentiation from epimastigotes to infective metacyclic trypomastigote forms.
The Journal of biological chemistry 1995;270(45):27244-53.
1995: Schneider P; Nikolaev A; Ferguson M A
The biosynthesis of GDP-D-arabinopyranose in Crithidia fasciculata: characterization of a D-arabino-1-kinase activity and its use in the synthesis of GDP-[5-3H]D-arabinopyranose.
The Biochemical journal 1995;311 ( Pt 1)():307-15.
1995: Redman C A; Schneider P; Mehlert A; Ferguson M A
The glycoinositol-phospholipids of Phytomonas.
The Biochemical journal 1995;311 ( Pt 2)():495-503.
1995: Pingel S; Field R A; Güther M L; Duszenko M; Ferguson M A
The hydrophobic mannoside Man alpha 1-6Man alpha 1-S-(CH2)7-CH3 acts as an acceptor for the UDP-Gal:glycosylphosphatidylinositol anchor alpha 1,3-galactosyltransferase of Trypanosoma brucei.
The Biochemical journal 1995;309 ( Pt 3)():877-82.
1995: Nikolaev A V; Chudek J A; Ferguson M A
The chemical synthesis of Leishmania donovani phosphoglycan via polycondensation of a glycobiosyl hydrogenphosphonate monomer.
Carbohydrate research 1995;272(2):179-89.
1995: Güther M L; Ferguson M A
The role of inositol acylation and inositol deacylation in GPI biosynthesis in Trypanosoma brucei.
The EMBO journal 1995;14(13):3080-93.
1995: Proudfoot L; Schneider P; Ferguson M A; McConville M J
Biosynthesis of the glycolipid anchor of lipophosphoglycan and the structurally related glycoinositolphospholipids from Leishmania major.
The Biochemical journal 1995;308 ( Pt 1)():45-55.
1995: Neville D C; Field R A; Ferguson M A
Hydrophobic glycosides of N-acetylglucosamine can act as primers for polylactosamine synthesis and can affect glycolipid synthesis in vivo.
The Biochemical journal 1995;307 ( Pt 3)():791-7.
1995: Treumann A; Lifely M R; Schneider P; Ferguson M A
Primary structure of CD52.
The Journal of biological chemistry 1995;270(11):6088-99.
1995: Heise N; de Almeida M L; Ferguson M A
Characterization of the lipid moiety of the glycosylphosphatidylinositol anchor of Trypanosoma cruzi 1G7-antigen.
Molecular and biochemical parasitology 1995;70(1-2):71-84.
1995: Schneider P; Ferguson M A
Microscale analysis of glycosylphosphatidylinositol structures.
Methods in enzymology 1995;250():614-30.
1994: Schneider P; Schnur L F; Jaffe C L; Ferguson M A; McConville M J
Glycoinositol-phospholipid profiles of four serotypically distinct Old World Leishmania strains.
The Biochemical journal 1994;304 ( Pt 2)():603-9.
1994: Almeida I C; Ferguson M A; Schenkman S; Travassos L R
Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosyl-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi.
The Biochemical journal 1994;304 ( Pt 3)():793-802.
1994: Redman C A; Thomas-Oates J E; Ogata S; Ikehara Y; Ferguson M A
Structure of the glycosylphosphatidylinositol membrane anchor of human placental alkaline phosphatase.
The Biochemical journal 1994;302 ( Pt 3)():861-5.
1994: Schneider P; McConville M J; Ferguson M A
Characterization of GDP-alpha-D-arabinopyranose, the precursor of D-Arap in Leishmania major lipophosphoglycan.
The Journal of biological chemistry 1994;269(28):18332-7.
1994: Güther M L; Masterson W J; Ferguson M A
The effects of phenylmethylsulfonyl fluoride on inositol-acylation and fatty acid remodeling in African trypanosomes.
The Journal of biological chemistry 1994;269(28):18694-701.
1994: Milne K G; Field R A; Masterson W J; Cottaz S; Brimacombe J S; Ferguson M A
Partial purification and characterization of the N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes.
The Journal of biological chemistry 1994;269(23):16403-8.
1994: Redman C A; Green B N; Thomas-Oates J E; Reinhold V N; Ferguson M A
Analysis of glycosylphosphatidylinositol membrane anchors by electrospray ionization-mass spectrometry and collision induced dissociation.
Glycoconjugate journal 1994;11(3):187-93.
1994: Almeida I C; Ferguson M A; Schenkman S; Travassos L R
GPI-anchored glycoconjugates from Trypanosoma cruzi trypomastigotes are recognized by lytic anti-alpha-galactosyl antibodies isolated from patients with chronic Chagas' disease.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):443-7.
1994: Mehlert A; Varon L; Silman I; Homans S W; Ferguson M A
Novel GPI structures of the membrane anchor of acetylcholinesterase from the electric organ of Torpedo californica.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):243-8.
1994: McConville M J; Schneider P; Proudfoot L; Masterson C; Ferguson M A
The developmental regulation and biosynthesis of GPI-related structures in Leishmania parasites.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):139-44.
1994: Güther M L; Masterson W J; Ferguson M A
The role of glycolipid C in the GPI biosynthetic pathway in Trypanosoma brucei bloodstream forms.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):121-6.
1994: Ferguson M A; Brimacombe J S; Cottaz S; Field R A; Güther L S; Homans S W; McConville M J; Mehlert A; Milne K G; Ralton J E
Glycosyl-phosphatidylinositol molecules of the parasite and the host.
Parasitology 1994;108 Suppl():S45-54.
1993: Mehlert A; Varon L; Silman I; Homans S W; Ferguson M A
Structure of the glycosyl-phosphatidylinositol membrane anchor of acetylcholinesterase from the electric organ of the electric-fish, Torpedo californica.
The Biochemical journal 1993;296 ( Pt 2)():473-9.
1993: Fankhauser C; Homans S W; Thomas-Oates J E; McConville M J; Desponds C; Conzelmann A; Ferguson M A
Structures of glycosylphosphatidylinositol membrane anchors from Saccharomyces cerevisiae.
The Journal of biological chemistry 1993;268(35):26365-74.
1993: Ralton J E; Milne K G; Güther M L; Field R A; Ferguson M A
The mechanism of inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei by mannosamine.
The Journal of biological chemistry 1993;268(32):24183-9.
1993: Schneider P; Rosat J P; Ransijn A; Ferguson M A; McConville M J
Characterization of glycoinositol phospholipids in the amastigote stage of the protozoan parasite Leishmania major.
The Biochemical journal 1993;295 ( Pt 2)():555-64.
1993: McConville M J; Ferguson M A
The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes.
The Biochemical journal 1993;294 ( Pt 2)():305-24.
1993: Cottaz S; Brimacombe J S; Ferguson M A
An imino-linked carba-disaccharide alpha-D-mannosidase inhibitor.
Carbohydrate research 1993;247():341-5.
1993: McConville M J; Collidge T A; Ferguson M A; Schneider P
The glycoinositol phospholipids of Leishmania mexicana promastigotes. Evidence for the presence of three distinct pathways of glycolipid biosynthesis.
The Journal of biological chemistry 1993;268(21):15595-604.
1993: Schenkman S; Ferguson M A; Heise N; de Almeida M L; Mortara R A; Yoshida N
Mucin-like glycoproteins linked to the membrane by glycosylphosphatidylinositol anchor are the major acceptors of sialic acid in a reaction catalyzed by trans-sialidase in metacyclic forms of Trypanosoma cruzi.
Molecular and biochemical parasitology 1993;59(2):293-303.
1993: Schneider P; Ralton J E; McConville M J; Ferguson M A
Analysis of the neutral glycan fractions of glycosyl-phosphatidylinositols by thin-layer chromatography.
Analytical biochemistry 1993;210(1):106-12.
1993: Ferguson M A; Murray P; Rutherford H; McConville M J
A simple purification of procyclic acidic repetitive protein and demonstration of a sialylated glycosyl-phosphatidylinositol membrane anchor.
The Biochemical journal 1993;291 ( Pt 1)():51-5.
1993: Mehlert A; Silman I; Homans S W; Ferguson M A
The structure of the glycosylphosphatidylinositol anchor from Torpedo californica acetylcholinesterase.
Biochemical Society transactions 1993;21(1):43S.
1992: McConville M J; Turco S J; Ferguson M A; Sacks D L
Developmental modification of lipophosphoglycan during the differentiation of Leishmania major promastigotes to an infectious stage.
The EMBO journal 1992;11(10):3593-600.
1992: Milne K G; Ferguson M A; Masterson W J
Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes.
European journal of biochemistry / FEBS 1992;208(2):309-14.
1992: Ferguson M A
Site of palmitoylation of a phospholipase C-resistant glycosylphosphatidylinositol membrane anchor.
The Biochemical journal 1992;284 ( Pt 2)():297-300.
1992: Ferguson M A
Colworth Medal Lecture. Glycosyl-phosphatidylinositol membrane anchors: the tale of a tail.
Biochemical Society transactions 1992;20(2):243-56.
1992: Thomas J R; McConville M J; Thomas-Oates J E; Homans S W; Ferguson M A; Gorin P A; Greis K D; Turco S J
Refined structure of the lipophosphoglycan of Leishmania donovani.
The Journal of biological chemistry 1992;267(10):6829-33.
1992: Güther M L; de Almeida M L; Yoshida N; Ferguson M A
Structural studies on the glycosylphosphatidylinositol membrane anchor of Trypanosoma cruzi 1G7-antigen. The structure of the glycan core.
The Journal of biological chemistry 1992;267(10):6820-8.
1991: Ferguson M A; Masterson W J; Homans S W; McConville M J
Evolutionary aspects of GPI metabolism in kinetoplastid parasites.
Cell biology international reports 1991;15(11):991-1005.
1991: Weinhart U; Thomas J R; Pak Y B; Thompson G A; Ferguson M A
Structural characterization of a novel glycosyl-phosphatidylinositol from the protozoan Tetrahymena mimbres.
The Biochemical journal 1991;279 ( Pt 2)():605-8.
1991: Masterson W J; Ferguson M A
Phenylmethanesulphonyl fluoride inhibits GPI anchor biosynthesis in the African trypanosome.
The EMBO journal 1991;10(8):2041-5.
1990: McConville M J; Thomas-Oates J E; Ferguson M A; Homans S W
Structure of the lipophosphoglycan from Leishmania major.
The Journal of biological chemistry 1990;265(32):19611-23.
1990: Schneider P; Ferguson M A; McConville M J; Mehlert A; Homans S W; Bordier C
Structure of the glycosyl-phosphatidylinositol membrane anchor of the Leishmania major promastigote surface protease.
The Journal of biological chemistry 1990;265(28):16955-64.

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