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Eduarda Fernandes

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TOP 3
Marisa Freitas; Graça Porto; Daniela Ribeiro; Félix Carvalho; Vera M Costa; Diana Couto; Eduarda Fernandes
Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils.
Patrícia Silva Ferreira; Andreas Meisel; Tiago Bernandes Nogueira; Maria Lourdes Bastos; Paula Sério Branco; Félix Carvalho; Vera Marisa Costa; Eduarda Fernandes; Luísa Maria Ferreira; João Paulo Capela
Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells.
Marisa Freitas; Pedro Barcellos-de-Souza; Christina Barja-Fidalgo; Eduarda Fernandes
Nickel induces apoptosis in human neutrophils.

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All Publications

2013: Marisa Freitas; Graça Porto; Daniela Ribeiro; Félix Carvalho; Vera M Costa; Diana Couto; Eduarda Fernandes
Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils.
Toxicology letters 2013;219(2):170-7.
2013: Patrícia Silva Ferreira; Andreas Meisel; Tiago Bernandes Nogueira; Maria Lourdes Bastos; Paula Sério Branco; Félix Carvalho; Vera Marisa Costa; Eduarda Fernandes; Luísa Maria Ferreira; João Paulo Capela
Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells.
Toxicology letters 2013;216(2-3):159-70.
2013: Marisa Freitas; Pedro Barcellos-de-Souza; Christina Barja-Fidalgo; Eduarda Fernandes
Nickel induces apoptosis in human neutrophils.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2013;26(1):13-21.
2013: João Paulo Capela; Maria de Lourdes Bastos; Vera Marisa Costa; Silvana da Costa Araújo; Ulrich Dirnagl; Eduarda Fernandes; Andreas Meisel; Karsten Ruscher; Félix Carvalho
The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons.
Neurotoxicology 2013;34():254-63.
2012: Ana Gomes; Graça Porto; Marisa Freitas; Andreia Alves; Diana Couto; Irene Dias; José Duarte; Eduarda Fernandes
Trihydroxyflavones with antioxidant and anti-inflammatory efficacy.
BioFactors (Oxford, England) 2012;38(5):378-86.
2012: Patrice Morlière; Larry K Patterson; Clementina M M Santos; Eduarda Fernandes; Paulo Filipe; M Beatriz Q Garcia; Ana Gomes; Jean-Claude Mazière; Artur M S Silva; René Santus
The dependence of α-tocopheroxyl radical reduction by hydroxy-2,3-diarylxanthones on structure and micro-environment.
Organic & biomolecular chemistry 2012;10(10):2068-76.
2012: Daniel José Barbosa; Paula Sério Branco; João Paulo Capela; Maria de Lourdes Bastos; José Alberto Duarte; Eduarda Fernandes; Luísa Maria Ferreira; Jorge Oliveira; Renata Silva; Filipa Siopa; Félix Carvalho
Pro-oxidant effects of Ecstasy and its metabolites in mouse brain synaptosomes.
British journal of pharmacology 2012;165(4b):1017-33.
2011: Marisa Freitas; Eduarda Fernandes
Zinc, cadmium and nickel increase the activation of NF-κB and the release of cytokines from THP-1 monocytic cells.
Metallomics : integrated biometal science 2011;3(11):1238-43.
2010: Marisa Freitas; Ana Gomes; Graça Porto; Eduarda Fernandes
Nickel induces oxidative burst, NF-κB activation and interleukin-8 production in human neutrophils.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2010;15(8):1275-83.
2010: Clementina M M Santos; Marisa Freitas; Daniela Ribeiro; Ana Gomes; Artur M S Silva; José A S Cavaleiro; Eduarda Fernandes
2,3-diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: a structure-activity relationship study.
Bioorganic & medicinal chemistry 2010;18(18):6776-84.
2010: Helena Pontes; Paula Guedes de Pinho; Eduarda Fernandes; Paula Sério Branco; Luísa Maria Ferreira; Helena Carmo; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Metabolic interactions between ethanol and MDMA in primary cultured rat hepatocytes.
Toxicology 2010;270(2-3):150-7.
2010: Marisa Freitas; Graça Porto; José L F C Lima; Eduarda Fernandes
Zinc activates neutrophils' oxidative burst.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2010;23(1):31-41.
2010: Diana Couto; Daniela Ribeiro; Marisa Freitas; Ana Gomes; José L F C Lima; Eduarda Fernandes
Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine.
Redox report : communications in free radical research 2010;15(6):259-67.
2010: Ana Gomes; Marisa Freitas; Eduarda Fernandes; José L F C Lima
Biological activities of 2-styrylchromones.
Mini reviews in medicinal chemistry 2010;10(1):1-7.
2009: Ana Gomes; Ondrej Neuwirth; Marisa Freitas; Diana Couto; Daniela Ribeiro; Andrea G P R Figueiredo; Artur M S Silva; Raquel S G R Seixas; Diana C G A Pinto; Augusto C Tomé; José A S Cavaleiro; Eduarda Fernandes; José L F C Lima
Synthesis and antioxidant properties of new chromone derivatives.
Bioorganic & medicinal chemistry 2009;17(20):7218-26.
2009: Isabel F Almeida; Paulo Cardoso Costa; Eduarda Fernandes; José L F C Lima; Maria Fernanda Bahia
In vitro protective effect of Hypericum androsaemum extract against oxygen and nitrogen reactive species.
Basic & clinical pharmacology & toxicology 2009;105(4):222-7.
2009: Marisa Freitas; José L F C Lima; Eduarda Fernandes
Optical probes for detection and quantification of neutrophils' oxidative burst. A review.
Analytica chimica acta 2009;649(1):8-23.
2009: Ana Gomes; Eduarda Fernandes; Artur M S Silva; Diana C G A Pinto; Clementina M M Santos; José A S Cavaleiro; José L F C Lima
Anti-inflammatory potential of 2-styrylchromones regarding their interference with arachidonic acid metabolic pathways.
Biochemical pharmacology 2009;78(2):171-7.
2009: Marisa Freitas; Graça Porto; José L F C Lima; Eduarda Fernandes
Optimization of experimental settings for the analysis of human neutrophils oxidative burst in vitro.
Talanta 2009;78(4-5):1476-83.
2009: Ema Alves; Teresa Summavielle; Cecília Juliana Alves; José Barata Antunes Custódio; Eduarda Fernandes; Maria de Lourdes Bastos; Maria Amélia Tavares; Félix Carvalho
Ecstasy-induced oxidative stress to adolescent rat brain mitochondria in vivo: influence of monoamine oxidase type A.
Addiction biology 2009;14(2):185-93.
2009: Isabel F Almeida; Eduarda Fernandes; José L F C Lima; Patrícia Valentão; Paula B Andrade; Rosa M Seabra; P C Costa; M F Bahia
Oxygen and nitrogen reactive species are effectively scavenged by Eucalyptus globulus leaf water extract.
Journal of medicinal food 2009;12(1):175-83.
2009: E Alves; Z Binienda; Félix Carvalho; C J Alves; Eduarda Fernandes; Maria de Lourdes Bastos; Maria Amélia Tavares; Teresa Summavielle
Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain.
Neuroscience 2009;158(2):514-23.
2008: Helena Pontes; Carla Sousa; Renata Silva; Eduarda Fernandes; Helena Carmo; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes.
Toxicology 2008;254(1-2):42-50.
2008: Helena Pontes; José Duarte; Paula Guedes de Pinho; Maria Elisa Soares; Eduarda Fernandes; Ricardo J Dinis-Oliveira; Carla Sousa; Renata Silva; Helena Carmo; Susana Casal; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Chronic exposure to ethanol exacerbates MDMA-induced hyperthermia and exposes liver to severe MDMA-induced toxicity in CD1 mice.
Toxicology 2008;252(1-3):64-71.
2008: Ana Gomes; Eduarda Fernandes; M Beatriz Q Garcia; Artur M S Silva; Diana C G A Pinto; Clementina M M Santos; José A S Cavaleiro; José L F C Lima
Cyclic voltammetric analysis of 2-styrylchromones: relationship with the antioxidant activity.
Bioorganic & medicinal chemistry 2008;16(17):7939-43.
2008: Teresa Sousa; Dora Pinho; Manuela Morato; José Marques-Lopes; Eduarda Fernandes; Joana Afonso; Sofia Oliveira; Félix Carvalho; António Albino-Teixeira
Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors.
European journal of pharmacology 2008;588(2-3):267-76.
2008: Helena Pontes; Maria João Santos-Marques; Eduarda Fernandes; José Duarte; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Effect of chronic ethanol exposure on the hepatotoxicity of ecstasy in mice: an ex vivo study.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(4):910-20.
2008: Isabel F Almeida; Eduarda Fernandes; José L F C Lima; P C Costa; M F Bahia
Protective effect of Castanea sativa and Quercus robur leaf extracts against oxygen and nitrogen reactive species.
Journal of photochemistry and photobiology. B, Biology 2008;91(2-3):87-95.
2008: Marisa Freitas; Graça Porto; José L F C Lima; Eduarda Fernandes
Isolation and activation of human neutrophils in vitro. The importance of the anticoagulant used during blood collection.
Clinical biochemistry 2008;41(7-8):570-5.
2008: Sanjay Gupta; Lígia M Rodrigues; Ana P Esteves; Ana M F Oliveira-Campos; Maria São José Nascimento; Naïr Nazareth; Honorina Cidade; Marta P Neves; Eduarda Fernandes; Madalena Pinto; Nuno Cerqueira; Natércia Brás
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors.
European journal of medicinal chemistry 2008;43(4):771-80.
2008: Ana Gomes; Eduarda Fernandes; José L F C Lima; Lurdes Mira; M Luísa Corvo
Molecular mechanisms of anti-inflammatory activity mediated by flavonoids.
Current medicinal chemistry 2008;15(16):1586-605.
2008: David Costa; Ana Gomes; José L F C Lima; Eduarda Fernandes
Singlet oxygen scavenging activity of non-steroidal anti-inflammatory drugs.
Redox report : communications in free radical research 2008;13(4):153-60.
2007: Ema Alves; Teresa Summavielle; Cecília Juliana Alves; Joana Gomes-da-Silva; José Custódio Barata; Eduarda Fernandes; Maria de Lourdes Bastos; Maria Amélia Tavares; Félix Carvalho
Monoamine oxidase-B mediates ecstasy-induced neurotoxic effects to adolescent rat brain mitochondria.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(38):10203-10.
2007: Ana Gomes; Eduarda Fernandes; Artur M S Silva; Clementina M M Santos; Diana C G A Pinto; José A S Cavaleiro; José L F C Lima
2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.
Bioorganic & medicinal chemistry 2007;15(18):6027-36.
2007: Marta F T Ribeiro; Ana C B Dias; João L M Santos; Eduarda Fernandes; José L F C Lima; Elias A G Zagatto
A multipumping flow system for in vitro screening of peroxynitrite scavengers.
Journal of biomolecular screening 2007;12(6):875-80.
2007: João Paulo Capela; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos; Andreas Meisel; Félix Carvalho
Ecstasy induces apoptosis via 5-HT(2A)-receptor stimulation in cortical neurons.
Neurotoxicology 2007;28(4):868-75.
2007: João Paulo Capela; C Macedo; Paula Sério Branco; Luísa Maria Ferreira; Ana Maria Lobo; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos; Ulrich Dirnagl; Andreas Meisel; Félix Carvalho
Neurotoxicity mechanisms of thioether ecstasy metabolites.
Neuroscience 2007;146(4):1743-57.
2007: David Costa; Eduarda Fernandes; João L M Santos; Diana C G A Pinto; Artur M S Silva; José L F C Lima
New noncellular fluorescence microplate screening assay for scavenging activity against singlet oxygen.
Analytical and bioanalytical chemistry 2007;387(6):2071-81.
2006: David Costa; Luís Moutinho; José L F C Lima; Eduarda Fernandes
Antioxidant activity and inhibition of human neutrophil oxidative burst mediated by arylpropionic acid non-steroidal anti-inflammatory drugs.
Biological & pharmaceutical bulletin 2006;29(8):1659-70.
2006: Ana Gomes; David Costa; José L F C Lima; Eduarda Fernandes
Antioxidant activity of beta-blockers: an effect mediated by scavenging reactive oxygen and nitrogen species?
Bioorganic & medicinal chemistry 2006;14(13):4568-77.
2006: David Costa; Alexandra P Marques; Rui L Reis; José L F C Lima; Eduarda Fernandes
Inhibition of human neutrophil oxidative burst by pyrazolone derivatives.
Free radical biology & medicine 2006;40(4):632-40.
2006: David Costa; Abel Vieira; Eduarda Fernandes
Dipyrone and aminopyrine are effective scavengers of reactive nitrogen species.
Redox report : communications in free radical research 2006;11(3):136-42.
2006: Ana Gomes; Eduarda Fernandes; José L F C Lima
Use of fluorescence probes for detection of reactive nitrogen species: a review.
Journal of fluorescence 2006;16(1):119-39.
2005: Ana Gomes; Eduarda Fernandes; José L F C Lima
Fluorescence probes used for detection of reactive oxygen species.
Journal of biochemical and biophysical methods 2005;65(2-3):45-80.
2005: Silvia R P Meneses; Karine L Marques; Cherrine K Pires; João L M Santos; Eduarda Fernandes; José L F C Lima; Elias A G Zagatto
Evaluation of the total antioxidant capacity by using a multipumping flow system with chemiluminescent detection.
Analytical biochemistry 2005;345(1):90-5.
2005: Eduarda Fernandes; Ana Gomes; David Costa; José L F C Lima
Pindolol is a potent scavenger of reactive nitrogen species.
Life sciences 2005;77(16):1983-92.
2005: David Costa; Ana Gomes; Salette Reis; José L F C Lima; Eduarda Fernandes
Hydrogen peroxide scavenging activity by non-steroidal anti-inflammatory drugs.
Life sciences 2005;76(24):2841-8.
2005: Teresa Sousa; Eduarda Fernandes; Carla Nunes; João Laranjinha; Félix Carvalho; Dora Pinho; Manuela Morato; António Albino-Teixeira
Scavenging of nitric oxide by an antagonist of adenosine receptors.
The Journal of pharmacy and pharmacology 2005;57(3):399-404.
2005: Helena Carmo; Jan G Hengstler; Douwe de Boer; Michael Ringel; Fernando Remião; Félix Carvalho; Eduarda Fernandes; Lesseps A dos Reys; Franz Oesch; Maria de Lourdes Bastos
Metabolic pathways of 4-bromo-2,5-dimethoxyphenethylamine (2C-B): analysis of phase I metabolism with hepatocytes of six species including human.
Toxicology 2005;206(1):75-89.
2004: Eduarda Fernandes; David Costa; Sofia A Toste; José L F C Lima; Salette Reis
In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs.
Free radical biology & medicine 2004;37(11):1895-905.
2004: Patrícia Valentão; Márcia Carvalho; Félix Carvalho; Eduarda Fernandes; Ricardo Neves; M Lourdes Pereira; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Hypericum androsaemum infusion increases tert-butyl hydroperoxide-induced mice hepatotoxicity in vivo.
Journal of ethnopharmacology 2004;94(2-3):345-51.
2004: Márcia Carvalho; Fernando Remião; Nuno Milhazes; Fernanda Borges; Eduarda Fernandes; Félix Carvalho; Maria Lourdes Bastos
The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
Toxicology 2004;200(2-3):193-203.
2004: José Duarte; Félix Carvalho; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos; José Magalhães; Hans J Appell
D-amphetamine-induced hydrogen peroxide production in skeletal muscle is modulated by monoamine oxidase inhibition.
International journal of sports medicine 2004;25(6):446-9.
2004: Cristovao F Lima; Félix Carvalho; Eduarda Fernandes; Maria Lourdes Bastos; Paula C Santos-Gomes; Manuel Fernandes-Ferreira; Cristina Pereira-Wilson
Evaluation of toxic/protective effects of the essential oil of Salvia officinalis on freshly isolated rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2004;18(4):457-65.
2004: Márcia Carvalho; Fernando Remião; Nuno Milhazes; Fernanda Borges; Eduarda Fernandes; Maria do Céu Monteiro; Maria José Gonçalves; VITOR SEABRA; Francisco M L Amado; Félix Carvalho; Maria Lourdes Bastos
Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro.
Chemical research in toxicology 2004;17(5):623-32.
2004: Patrícia Valentão; Márcia Carvalho; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria de Lourdes Bastos
Protective activity of Hypericum androsaemum infusion against tert-butyl hydroperoxide-induced oxidative damage in isolated rat hepatocytes.
Journal of ethnopharmacology 2004;92(1):79-84.
2004: Teresa Sousa; Manuela Morato; Eduarda Fernandes; Félix Carvalho; António Albino-Teixeira
Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.
Journal of enzyme inhibition and medicinal chemistry 2004;19(1):11-5.
2004: Helena Carmo; Jan G Hengstler; Douwe de Boer; Michael Ringel; Félix Carvalho; Eduarda Fernandes; Fernando Remião; Lesseps A dos Reys; Franz Oesch; Maria de Lourdes Bastos
Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(2):198-205.
2004: Márcia Carvalho; Nuno Milhazes; Fernando Remião; Fernanda Borges; Eduarda Fernandes; Francisco M L Amado; Terrence J Monks; Félix Carvalho; Maria Lourdes Bastos
Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates.
Archives of toxicology 2004;78(1):16-24.
2003: Eduarda Fernandes; Sofia A Toste; José L F C Lima; Salette Reis
The metabolism of sulindac enhances its scavenging activity against reactive oxygen and nitrogen species.
Free radical biology & medicine 2003;35(9):1008-17.
2003: Eduarda Fernandes; Márcia Carvalho; Félix Carvalho; Artur M S Silva; Clementina M M Santos; Diana C G A Pinto; José A S Cavaleiro; Maria de Lourdes Bastos
Hepatoprotective activity of polyhydroxylated 2-styrylchromones against tert-butylhydroperoxide induced toxicity in freshly isolated rat hepatocytes.
Archives of toxicology 2003;77(9):500-5.
2003: Helena Carmo; Fernando Remião; Félix Carvalho; Eduarda Fernandes; Douwe de Boer; Lesseps A dos Reys; Maria de Lourdes Bastos
4-Methylthioamphetamine-induced hyperthermia in mice: influence of serotonergic and catecholaminergic pathways.
Toxicology and applied pharmacology 2003;190(3):262-71.
2003: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Hydroxyl radical and hypochlorous acid scavenging activity of small centaury (Centaurium erythraea) infusion. A comparative study with green tea (Camellia sinensis).
Phytomedicine : international journal of phytotherapy and phytopharmacology 2003;10(6-7):517-22.
2002: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria de Lourdes Basto
Studies on the antioxidant activity of Lippia citriodora infusion: scavenging effect on superoxide radical, hydroxyl radical and hypochlorous acid.
Biological & pharmaceutical bulletin 2002;25(10):1324-7.
2002: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria de Lourdes Bastos
Antioxidant activity of Hypericum androsaemum infusion: scavenging activity against superoxide radical, hydroxyl radical and hypochlorous acid.
Biological & pharmaceutical bulletin 2002;25(10):1320-3.
2002: Márcia Carvalho; Gabrielle Hawksworth; Nuno Milhazes; Fernanda Borges; Terrence J Monks; Eduarda Fernandes; Félix Carvalho; Maria Lourdes Bastos
Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells.
Archives of toxicology 2002;76(10):581-8.
2002: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid.
Journal of agricultural and food chemistry 2002;50(17):4989-93.
2002: Eduarda Fernandes; Félix Carvalho; Artur M S Silva; Clementina M M Santos; Diana C G A Pinto; José A S Cavaleiro; Maria de Lourdes Bastos
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
Journal of enzyme inhibition and medicinal chemistry 2002;17(1):45-8.
2002: Fernanda Borges; Eduarda Fernandes; F Roleira
Progress towards the discovery of xanthine oxidase inhibitors.
Current medicinal chemistry 2002;9(2):195-217.
2001: Félix Carvalho; José Duarte; Maria J Neuparth; Helena Carmo; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos
Hydrogen peroxide production in mouse tissues after acute d-amphetamine administration. Influence of monoamine oxidase inhibition.
Archives of toxicology 2001;75(8):465-9.
2001: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity.
Journal of agricultural and food chemistry 2001;49(7):3476-9.
1999: Félix Carvalho; Eduarda Fernandes; Fernando Remião; Maria de Lourdes Bastos
Effect of d-amphetamine repeated administration on rat antioxidant defences.
Archives of toxicology 1999;73(2):83-9.