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2006: Eran Dvir; Jonathan E Friedman; J Y Lee; J Y Koh; F Younis; Sarah Raz; I Shapiro; Amnon Hoffman; Arik Dahan; G Rosenberg; Itzchak Angel; Alex Kozak; Revital Duvdevani
A novel phospholipid derivative of indomethacin, DP-155 [mixture of 1-steroyl and 1-palmitoyl-2-{6-[1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolyl acetamido]hexanoyl}-sn-glycero-3-phosophatidyl [corrected] choline], shows superior safety and similar efficacy in reducing brain amyloid beta in an Alzheimer's disease model.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1248-56.
2005: Gilad Rosenberg; Itzchak Angel; Alex Kozak
Clinical pharmacology of DP-b99 in healthy volunteers: first administration to humans.
British journal of clinical pharmacology 2005;60(1):7-16.
2004: Joo-Yong Lee; Jonathan E Friedman; Itzchak Angel; Alex Kozak; Jae-Young Koh
The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice.
Neurobiology of aging 2004;25(10):1315-21.