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Bo Angelin

Research Profile

Chemicals & Drugs

Anatomy

Livers
Bile

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Sama I Sayin; Annika Wahlström; Bo Angelin; Krister Bamberg; Jenny Felin; Tuulia Hyötyläinen; Sirkku Jäntti; Hanns-Ulrich Marschall; Matej Oresic; Fredrik Bäckhed
Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist.
Bo Angelin; Tobias E Larsson; Mats Rudling
Circulating fibroblast growth factors as metabolic regulators--a critical appraisal.
Ylva Bonde; Folkert Kuipers; Torsten Plösch; Bo Angelin; Mats Rudling
Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex.

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2013: Sama I Sayin; Annika Wahlström; Bo Angelin; Krister Bamberg; Jenny Felin; Tuulia Hyötyläinen; Sirkku Jäntti; Hanns-Ulrich Marschall; Matej Oresic; Fredrik Bäckhed
Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist.
Cell metabolism 2013;17(2):225-35.
2012: Bo Angelin; Tobias E Larsson; Mats Rudling
Circulating fibroblast growth factors as metabolic regulators--a critical appraisal.
Cell metabolism 2012;16(6):693-705.
2012: Ylva Bonde; Folkert Kuipers; Torsten Plösch; Bo Angelin; Mats Rudling
Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex.
Hepatology (Baltimore, Md.) 2012;56(5):1828-37.
2012: Jason S Troutt; Bo Angelin; Anthony M Butterfield; Guoqing Cao; Lena Persson; Mats Rudling; Andrew E Schade; Lars Ståhle; Robert J Konrad
Circulating human hepcidin-25 concentrations display a diurnal rhythm, increase with prolonged fasting, and are reduced by growth hormone administration.
Clinical chemistry 2012;58(8):1225-32.
2012: Lena Persson; Bo Angelin; Peter Henriksson; Outi Hovatta; Eli Westerlund; Mats Rudling
Endogenous estrogens lower plasma PCSK9 and LDL cholesterol but not Lp(a) or bile acid synthesis in women.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(3):810-4.
2012: Thomas Lundåsen; Johanna Lundberg; Eva-Marie Andersson; Bo Angelin; Helena Lindmark; Michael Snaith; Ann-Margret Östlund-Lindqvist; Mats Rudling
Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.
PloS one 2012;7(5):e37787.
2010: Bo Angelin; Mats Rudling
Lipid lowering with thyroid hormone and thyromimetics.
Current opinion in lipidology 2010;21(6):499-506.
2010: Lena Persson; Guoqing Cao; Lars Ståhle; Beatrice G Sjöberg; Jason S Troutt; Robert J Konrad; Cecilia Gälman; Håkan Wallén; Mats Eriksson; Ingiäld Hafström; Suzanne Lind; Maria Dahlin; Per Amark; Bo Angelin; Mats Rudling
Circulating proprotein convertase subtilisin kexin type 9 has a diurnal rhythm synchronous with cholesterol synthesis and is reduced by fasting in humans.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(12):2666-72.
2010: Paul W Ladenson; Jens D Kristensen; E Chester Ridgway; Anders G Olsson; Bo Carlsson; Irwin Klein; John D Baxter; Bo Angelin
Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia.
The New England journal of medicine 2010;362(10):906-16.
2009: Camilla Pramfalk; E Karlsson; L Groop; Lawrence L Rudel; Bo Angelin; Mats Eriksson; Paolo Parini
Control of ACAT2 liver expression by HNF4{alpha}: lesson from MODY1 patients.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(8):1235-41.
2009: Lena Persson; Cecilia Gälman; Bo Angelin; Mats Rudling
Importance of proprotein convertase subtilisin/kexin type 9 in the hormonal and dietary regulation of rat liver low-density lipoprotein receptors.
Endocrinology 2009;150(3):1140-6.
2008: Cecilia Gälman; Tomas Lundåsen; Alexei Kharitonenkov; Holly A Bina; Mats Eriksson; Ingiäld Hafström; Maria Dahlin; Per Amark; Bo Angelin; Mats Rudling
The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.
Cell metabolism 2008;8(2):169-74.
2008: Paolo Parini; Ulf Gustafsson; Matt A Davis; Lilian Larsson; Curt Einarsson; Martha Wilson; Mats Rudling; Hiroshi Tomoda; Satoshi Omura; Staffan Sahlin; Bo Angelin; Lawrence L Rudel; Mats Eriksson
Cholesterol synthesis inhibition elicits an integrated molecular response in human livers including decreased ACAT2.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(6):1200-6.
2008: Cecilia Gälman; Ylva Bonde; Manuela Matasconi; Bo Angelin; Mats Rudling
Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone.
Gastroenterology 2008;134(4):1127-36.
2008: Anders Berkenstam; Jens Kristensen; Karin Mellström; Bo Carlsson; Johan Malm; Stefan Rehnmark; Neeraj Garg; Carl Magnus Andersson; Mats Rudling; Folke Sjöberg; Bo Angelin; John D Baxter
The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(2):663-7.
2007: Camilla Pramfalk; Bo Angelin; Mats Eriksson; Paolo Parini
Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells.
Biochemical and biophysical research communications 2007;364(2):402-9.
2007: Cecilia Gälman; Manuela Matasconi; Lena Persson; Paolo Parini; Bo Angelin; Mats Rudling
Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol.
American journal of physiology. Endocrinology and metabolism 2007;293(3):E737-42.
2007: Thomas Lundåsen; Mary C Hunt; Lisa-Mari Nilsson; Sabyasachi Sanyal; Bo Angelin; Stefan E H Alexson; Mats Rudling
PPARalpha is a key regulator of hepatic FGF21.
Biochemical and biophysical research communications 2007;360(2):437-40.
2007: Lisa-Mari Nilsson; Anna Abrahamsson; Staffan Sahlin; Ulf Gustafsson; Bo Angelin; Paolo Parini; Curt Einarsson
Bile acids and lipoprotein metabolism: effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression.
Biochemical and biophysical research communications 2007;357(3):707-11.
2006: Thomas Lundåsen; Cecilia Gälman; Bo Angelin; Mats Rudling
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.
Journal of internal medicine 2006;260(6):530-6.
2006: Göran Walldius; Bo Angelin; Mats Eriksson
[The apoB/apoA-I ratio is better myocardial infarction marker than lipids].
Läkartidningen 2006;103(10):751-2.
2006: Paolo Parini; L Johansson; Anders Bröijersén; Bo Angelin; Mats Rudling
Lipoprotein profiles in plasma and interstitial fluid analyzed with an automated gel-filtration system.
European journal of clinical investigation 2006;36(2):98-104.
2005: Cecilia Gälman; Bo Angelin; Mats Rudling
Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis.
Gastroenterology 2005;129(5):1445-53.
2005: Bo Angelin
Telling the liver (not) to make bile acids: a new voice from the gut?
Cell metabolism 2005;2(4):209-10.
2005: Manuela Matasconi; Paolo Parini; Bo Angelin; Mats Rudling
Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: effects of hypophysectomy and growth hormone treatment.
Biochimica et biophysica acta 2005;1736(3):221-7.
2005: Anna Abrahamsson; Sergey Krapivner; Ulf Gustafsson; Olle Muhrbeck; Gösta Eggertsen; Inger Johansson; Irene Persson; Bo Angelin; Magnus Ingelman-Sundberg; Ingemar Björkhem; Curt Einarsson; Ferdinand M van't Hooft
Common polymorphisms in the CYP7A1 gene do not contribute to variation in rates of bile acid synthesis and plasma LDL cholesterol concentration.
Atherosclerosis 2005;182(1):37-45.
2005: Lisen Johansson; Mats Rudling; Thomas S Scanlan; Thomas Lundåsen; Paul Webb; John Baxter; Bo Angelin; Paolo Parini
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(29):10297-302.
2005: Margaret E Brousseau; Margaret R Diffenderfer; John S Millar; Chorthip Nartsupha; Bela F Asztalos; Francine K Welty; Megan L Wolfe; Mats Rudling; Ingemar Björkhem; Bo Angelin; James P Mancuso; Andres G Digenio; Daniel J Rader; Ernst Schaefer
Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(5):1057-64.
2004: Suzanne Lind; Anders G Olsson; Mats Eriksson; Mats Rudling; Gösta Eggertsen; Bo Angelin
Autosomal recessive hypercholesterolaemia: normalization of plasma LDL cholesterol by ezetimibe in combination with statin treatment.
Journal of internal medicine 2004;256(5):406-12.
2004: Anne-Maj Samuelsson; Iris Ohrn; Jovanna Dahlgren; Elias Eriksson; Bo Angelin; Björn Folkow; Agneta Holmäng
Prenatal exposure to interleukin-6 results in hypertension and increased hypothalamic-pituitary-adrenal axis activity in adult rats.
Endocrinology 2004;145(11):4897-911.
2004: Paolo Parini; Matthew Davis; Aaron T Lada; Sandra K Erickson; Teresa L Wright; Ulf Gustafsson; Staffan Sahlin; Curt Einarsson; Mats Eriksson; Bo Angelin; Hiroshi Tomoda; Satoshi Omura; Mark C Willingham; Lawrence L Rudel
ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver.
Circulation 2004;110(14):2017-23.
2004: Manuela Matasconi; Bo Angelin; Mats Rudling
Pituitary control of lipoprotein and bile acid metabolism in male rats: growth hormone effects are not mediated by prolactin.
American journal of physiology. Endocrinology and metabolism 2004;287(1):E114-9.
2004: Ebba Brakenhielm; Renhai Cao; Bihu Gao; Bo Angelin; Barbara Cannon; Paolo Parini; Yihai Cao
Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice.
Circulation research 2004;94(12):1579-88.
2004: Suzanne Lind; Mats Rudling; Sverker Ericsson; Hans Olivecrona; Mats Eriksson; Birgit Borgström; Gösta Eggertsen; Lars Berglund; Bo Angelin
Growth hormone induces low-density lipoprotein clearance but not bile acid synthesis in humans.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(2):349-56.
2003: Thomas Lundåsen; Wei Liao; Bo Angelin; Mats Rudling
Leptin induces the hepatic high density lipoprotein receptor scavenger receptor B type I (SR-BI) but not cholesterol 7alpha-hydroxylase (Cyp7a1) in leptin-deficient (ob/ob) mice.
The Journal of biological chemistry 2003;278(44):43224-8.
2003: Bethan Jones; Emma L Jones; Stephanie A Bonney; Hetal N Patel; Arjen Mensenkamp; Sophie Eichenbaum-Voline; Mats Rudling; Urban Myrdal; Grazia Annesi; Sandhia Naik; Nigel Meadows; Aldo Quattrone; Suhail A Islam; Rossi P Naoumova; Bo Angelin; Recaredo Infante; Emile Levy; Claude C Roy; Paul S Freemont; James Scott; Carol C Shoulders
Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders.
Nature genetics 2003;34(1):29-31.
2003: Cecilia Gälman; Ingela Arvidsson; Bo Angelin; Mats Rudling
Monitoring hepatic cholesterol 7alpha-hydroxylase activity by assay of the stable bile acid intermediate 7alpha-hydroxy-4-cholesten-3-one in peripheral blood.
Journal of lipid research 2003;44(4):859-66.
2003: Cecilia Gälman; Ann-Margret Ostlund-Lindqvist; Anna Björquist; Sandra Schreyer; Lennart Svensson; Bo Angelin; Mats Rudling
Pharmacological interference with intestinal bile acid transport reduces plasma cholesterol in LDL receptor/apoE deficiency.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):265-7.
2002: Bo Angelin; Paolo Parini; Mats Eriksson
Reverse cholesterol transport in man: promotion of fecal steroid excretion by infusion of reconstituted HDL.
Atherosclerosis. Supplements 2002;3(4):23-30.
2002: Mats Rudling; Bo Angelin; Lars Ståhle; Eva Reihnér; Staffan Sahlin; Hans Olivecrona; Ingemar Björkhem; Curt Einarsson
Regulation of hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and cholesterol 7alpha-hydroxylase mRNAs in human liver.
The Journal of clinical endocrinology and metabolism 2002;87(9):4307-13.
2002: Gertrud U Schuster; Paolo Parini; Ling Wang; Siegfried Alberti; Knut R Steffensen; Göran K Hansson; Bo Angelin; Jan-�ke GUSTAFSSON
Accumulation of foam cells in liver X receptor-deficient mice.
Circulation 2002;106(9):1147-53.
2002: Hjalmar Gullberg; Mats Rudling; Carmen Saltó; Douglas Forrest; Bo Angelin; Björn Vennström
Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice.
Molecular endocrinology (Baltimore, Md.) 2002;16(8):1767-77.
2002: Suzanne Lind; Eva Rystedt; Mats Eriksson; O Wiklund; Bo Angelin; Gösta Eggertsen
Genetic characterization of Swedish patients with familial hypercholesterolemia: a heterogeneous pattern of mutations in the LDL receptor gene.
Atherosclerosis 2002;163(2):399-407.
2002: Ingemar Björkhem; Zufan Araya; Mats Rudling; Bo Angelin; Curt Einarsson; Kjell Wikvall
Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1.
The Journal of biological chemistry 2002;277(30):26804-7.
2002: Cecilia Gälman; Bo Angelin; Mats Rudling
Prolonged stimulation of the adrenals by corticotropin suppresses hepatic low-density lipoprotein and high-density lipoprotein receptors and increases plasma cholesterol.
Endocrinology 2002;143(5):1809-16.
2002: Katharina Slätis; Majid Mohammadieh; Anders Bröijersén; Bo Angelin; Mats Gåfvels
Dexamethasone stimulates very low density lipoprotein (VLDL) receptor gene expression in differentiating 3T3-L1 cells.
Biochimica et biophysica acta 2002;1581(1-2):36-48.
2001: Anders Bröijersén; B Wiklund; Bo Angelin
[Blood lipid derangement common in peripheral artery disease. Lipid-lowering agents may alleviate symptoms and slow the atherosclerotic process].
Läkartidningen 2001;98(36):3788-93.
2001: Mats Rudling; Bo Angelin
Growth hormone reduces plasma cholesterol in LDL receptor-deficient mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(8):1350-6.
2001: Siegfried Alberti; Gertrud Schuster; Paolo Parini; D Feltkamp; Ulf Diczfalusy; Mats Rudling; Bo Angelin; Ingemar Björkhem; S Pettersson; Jan-�ke GUSTAFSSON
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice.
The Journal of clinical investigation 2001;107(5):565-73.
2000: Claes Ohlsson; N Hellberg; Paolo Parini; ON Vidal; Mohammad Bohlooly-Y; M Bohlooly; Mats Rudling; Marie K Lindberg; M Warner; Bo Angelin; Jan-�ke GUSTAFSSON
Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice.
Biochemical and biophysical research communications 2000;278(3):640-5.
2000: Hjalmar Gullberg; Mats Rudling; Douglas Forrest; Bo Angelin; Björn Vennström
Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol.
Molecular endocrinology (Baltimore, Md.) 2000;14(11):1739-49.
2000: Peter Stenvinkel; A Alvestrand; Bo Angelin; M Eriksson
LDL-apheresis in patients with nephrotic syndrome: effects on serum albumin and urinary albumin excretion.
European journal of clinical investigation 2000;30(10):866-70.
2000: Paolo Parini; Bo Angelin; A Stavréus-Evers; Bo Freyschuss; H Eriksson; Mats Rudling
Biphasic effects of the natural estrogen 17beta-estradiol on hepatic cholesterol metabolism in intact female rats.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(7):1817-23.
1999: CG Hillebrant; B Nyberg; Bo Angelin; Magnus Axelson; Ingemar Björkhem; Mats Rudling; Curt Einarsson
Deoxycholic acid treatment in patients with cholesterol gallstones: failure to detect a suppression of cholesterol 7alpha-hydroxylase activity.
Journal of internal medicine 1999;246(4):399-407.
1999: M Eriksson; L A Carlson; T A Miettinen; Bo Angelin
Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans.
Circulation 1999;100(6):594-8.
1999: Bo Angelin; M Eriksson; Mats Rudling
Bile acids and lipoprotein metabolism: a renaissance for bile acids in the post-statin era?
Current opinion in lipidology 1999;10(3):269-74.
1999: L Nilsson; Mats Gåfvels; L Musakka; Katharina Slätis; Dudley K Strickland; Bo Angelin; Anders Hamsten; Per Eriksson
VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor.
Journal of lipid research 1999;40(5):913-9.
1999: Mats Rudling; Paolo Parini; Bo Angelin
Effects of growth hormone on hepatic cholesterol metabolism. Lessons from studies in rats and humans.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1999;9 Suppl A():1-7.
1999: A Weryński; Z Nahorski; Lars Berglund; Sverker Ericsson; Bo Angelin; M Eriksson
Evidence of circadian rhythm in low-density lipoprotein apoB catabolism and its impact on the estimation of kinetic parameters.
European journal of clinical investigation 1999;29(4):291-300.
1999: Paolo Parini; Bo Angelin; Mats Rudling
Cholesterol and lipoprotein metabolism in aging: reversal of hypercholesterolemia by growth hormone treatment in old rats.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(4):832-9.
1999: Hans Olivecrona; Agneta Hilding; C Ekström; Hans Barle; B Nyberg; C Möller; P J Delhanty; R C Baxter; Bo Angelin; Tomas J Ekström; Michael Tally
Acute and short-term effects of growth hormone on insulin-like growth factors and their binding proteins: serum levels and hepatic messenger ribonucleic acid responses in humans.
The Journal of clinical endocrinology and metabolism 1999;84(2):553-60.
1998: Mats Rudling; Mats Gåfvels; Paolo Parini; G Gahrton; Bo Angelin
Lipoprotein receptors in acute myelogenous leukemia: failure to detect increased low-density lipoprotein (LDL) receptor numbers in cell membranes despite increased cellular LDL degradation.
The American journal of pathology 1998;153(6):1923-35.
1998: Magnus Axelson; Bo Angelin; CG Hillebrant; Eva Reihnér; Curt Einarsson
The level of 7-dehydrocholesterol in plasma reflects the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the human liver.
Biochimica et biophysica acta 1998;1394(2-3):153-7.
1998: J Magrané; Manuel Reina; Roser Pagan; A Luna; Ricardo P Casaroli-Marano; Bo Angelin; Mats Gåfvels; Senén Vilaró
Bovine aortic endothelial cells express a variant of the very low density lipoprotein receptor that lacks the O-linked sugar domain.
Journal of lipid research 1998;39(11):2172-81.
1998: Suzanne Lind; Mats Eriksson; Eva Rystedt; O Wiklund; Bo Angelin; Gösta Eggertsen
Low frequency of the common Norwegian and Finnish LDL-receptor mutations in Swedish patients with familial hypercholesterolaemia.
Journal of internal medicine 1998;244(1):19-25.
1998: Bertil Casslén; Barbro Gustavsson; Bo Angelin; Mats Gåfvels
Degradation of urokinase plasminogen activator (UPA) in endometrial stromal cells requires both the UPA receptor and the low-density lipoprotein receptor-related protein/alpha2-macroglobulin receptor.
Molecular human reproduction 1998;4(6):585-93.
1998: F Aberg; EL Appelkvist; Anders Bröijersén; M Eriksson; Bo Angelin; Paul Hjemdahl; Gustav Dallner
Gemfibrozil-induced decrease in serum ubiquinone and alpha- and gamma-tocopherol levels in men with combined hyperlipidaemia.
European journal of clinical investigation 1998;28(3):235-42.
1997: Sverker Ericsson; Lars Berglund; Johan Frostegård; K Einarsson; Bo Angelin
The influence of age on low density lipoprotein metabolism: effects of cholestyramine treatment in young and old healthy male subjects.
Journal of internal medicine 1997;242(4):329-37.
1997: Paolo Parini; Bo Angelin; Mats Rudling
Importance of estrogen receptors in hepatic LDL receptor regulation.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(9):1800-5.
1997: D Ståhlberg; Mats Rudling; Bo Angelin; I Björkhem; P Forsell; K Nilsell; K Einarsson
Hepatic cholesterol metabolism in human obesity.
Hepatology (Baltimore, Md.) 1997;25(6):1447-50.
1997: Mats Rudling; Paolo Parini; Bo Angelin
Growth hormone and bile acid synthesis. Key role for the activity of hepatic microsomal cholesterol 7alpha-hydroxylase in the rat.
The Journal of clinical investigation 1997;99(9):2239-45.
1997: W Liao; Mats Rudling; Bo Angelin
Novel effects of histamine on lipoprotein metabolism: suppression of hepatic low density lipoprotein receptor expression and reduction of plasma high density lipoprotein cholesterol in the rat.
Endocrinology 1997;138(5):1863-70.
1997: S Vitols; Bo Angelin; Gunnar Juliusson
Simvastatin impairs mitogen-induced proliferation of malignant B-lymphocytes from humans--in vitro and in vivo studies.
Lipids 1997;32(3):255-62.
1997: Anders Bröijersén; M Eriksson; B Leijd; Bo Angelin; Paul Hjemdahl
No influence of simvastatin treatment on platelet function in vivo in patients with hypercholesterolemia.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(2):273-8.
1997: Peter Stenvinkel; Lars Berglund; Sverker Ericsson; A Alvestrand; Bo Angelin; M Eriksson
Low-density lipoprotein metabolism and its association to plasma lipoprotein(a) in the nephrotic syndrome.
European journal of clinical investigation 1997;27(2):169-77.
1997: Bo-Göran Ericzon; S Eusufzai; Gunnar Söderdahl; Frans Duraj; K Einarsson; Bo Angelin
Secretion and composition of bile after human liver transplantation: studies on the effects of cyclosporine and tacrolimus.
Transplantation 1997;63(1):74-80.
1996: Anders Bröijersén; Anders Hamsten; Angela Silveira; K Fatah; Alison H Goodall; M Eriksson; Bo Angelin; Paul Hjemdahl
Gemfibrozil reduces thrombin generation in patients with combined hyperlipidaemia, without influencing plasma fibrinogen, fibrin gel structure or coagulation factor VII.
Thrombosis and haemostasis 1996;76(2):171-6.
1996: A Bröijersen; M Eriksson; B Wiman; Bo Angelin; Paul Hjemdahl
Gemfibrozil treatment of combined hyperlipoproteinemia. No improvement of fibrinolysis despite marked reduction of plasma triglyceride levels.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(4):511-6.
1996: Mats Rudling; H Olivecrona; Gösta Eggertsen; Bo Angelin
Regulation of rat hepatic low density lipoprotein receptors. In vivo stimulation by growth hormone is not mediated by insulin-like growth factor I.
The Journal of clinical investigation 1996;97(2):292-9.
1995: Paolo Parini; Bo Angelin; P E Lobie; G Norstedt; Mats Rudling
Growth hormone specifically stimulates the expression of low density lipoprotein receptors in human hepatoma cells.
Endocrinology 1995;136(9):3767-73.
1995: H Olivecrona; AG Johansson; E Lindh; S Ljunghall; Lars Berglund; Bo Angelin
Hormonal regulation of serum lipoprotein(a) levels. Contrasting effects of growth hormone and insulin-like growth factor-I.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(7):847-9.
1995: S Reynisdottir; M Eriksson; Bo Angelin; Peter Arner
Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia.
The Journal of clinical investigation 1995;95(5):2161-9.
1995: Dagny Ståhlberg; E Reihnér; Mats Rudling; Lars Berglund; K Einarsson; Bo Angelin
Influence of bezafibrate on hepatic cholesterol metabolism in gallstone patients: reduced activity of cholesterol 7 alpha-hydroxylase.
Hepatology (Baltimore, Md.) 1995;21(4):1025-30.
1995: Bo Angelin
1994 Mack-Forster Award Lecture. Review. Studies on the regulation of hepatic cholesterol metabolism in humans.
European journal of clinical investigation 1995;25(4):215-24.
1995: A Bröijersén; M Eriksson; Bo Angelin; P Hjemdahl
Gemfibrozil enhances platelet activity in patients with combined hyperlipoproteinemia.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(1):121-7.
1994: Gösta Eggertsen; M Eriksson; Olov Wiklund; A Iitiä; Sven-Olof Olofsson; Bo Angelin; Lars Berglund
Time-resolved fluorometry in the genetic diagnosis of familial defective apolipoprotein B-100.
Journal of lipid research 1994;35(8):1505-8.
1994: Anders Bröijersén; M Eriksson; P T Larsson; O Beck; Lars Berglund; Bo Angelin; Paul Hjemdahl
Effects of selective LDL-apheresis and pravastatin therapy on platelet function in familial hypercholesterolaemia.
European journal of clinical investigation 1994;24(7):488-98.
1994: Bo Angelin; Mats Rudling
Growth hormone and hepatic lipoprotein metabolism.
Current opinion in lipidology 1994;5(3):160-5.
1993: M Eriksson; Lars Berglund; J Gabrielsson; B Lantz; Bo Angelin
Non-steady-state kinetics of low density lipoproteins in man: studies after plasma exchange in healthy subjects and patients with familial hypercholesterolaemia.
European journal of clinical investigation 1993;23(11):746-52.
1993: Mats Rudling; Bo Angelin
Loss of resistance to dietary cholesterol in the rat after hypophysectomy: importance of the presence of growth hormone for hepatic low density lipoprotein-receptor expression.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8851-5.
1993: Peter Arner; Hans Wahrenberg; Fredrik Lönnqvist; Bo Angelin
Adipocyte beta-adrenoceptor sensitivity influences plasma lipid levels.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(7):967-72.
1993: H Olivecrona; S Ericsson; Lars Berglund; Bo Angelin
Increased concentrations of serum lipoprotein (a) in response to growth hormone treatment.
BMJ (Clinical research ed.) 1993;306(6894):1726-7.
1993: Mats Rudling; Bo Angelin
Stimulation of rat hepatic low density lipoprotein receptors by glucagon. Evidence of a novel regulatory mechanism in vivo.
The Journal of clinical investigation 1993;91(6):2796-805.
1993: Bo Angelin; H Olivecrona; S Ericsson; Mats Rudling
Growth hormone and low-density lipoproteins.
Acta endocrinologica 1993;128 Suppl 2():26-8.
1993: Lars Berglund; Olov Wiklund; Gösta Eggertsen; Sven-Olof Olofsson; M Eriksson; T Lindén; Göran Bondjers; Bo Angelin
Apolipoprotein E phenotypes in familial hypercholesterolaemia: importance for expression of disease and response to therapy.
Journal of internal medicine 1993;233(2):173-8.
1993: Olov Wiklund; Bo Angelin; M Bergman; Lars Berglund; Göran Bondjers; A Carlsson; T Lindén; T Miettinen; B Odman; Sven-Olof Olofsson
Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia.
The American journal of medicine 1993;94(1):13-20.
1992: Bo Angelin; H Olivecrona; E Reihnér; Mats Rudling; Dagny Ståhlberg; M Eriksson; S Ewerth; P Henriksson; K Einarsson
Hepatic cholesterol metabolism in estrogen-treated men.
Gastroenterology 1992;103(5):1657-63.
1992: S Ericsson; M Eriksson; Lars Berglund; Bo Angelin
Metabolism of plasma low density lipoproteins in familial combined hyperlipidaemia: effect of acipimox therapy.
Journal of internal medicine 1992;232(4):313-20.
1992: Bo Angelin; Mats Rudling; H Olivecrona; S Ericsson
Effects of growth hormone on low-density lipoprotein metabolism.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1992;383():67-8; discussion 69.
1992: Mats Rudling; G Norstedt; H Olivecrona; E Reihnér; J A Gustafsson; Bo Angelin
Importance of growth hormone for the induction of hepatic low density lipoprotein receptors.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):6983-7.
1992: P Henriksson; Bo Angelin; Lars Berglund
Hormonal regulation of serum Lp (a) levels. Opposite effects after estrogen treatment and orchidectomy in males with prostatic carcinoma.
The Journal of clinical investigation 1992;89(4):1166-71.
1992: Bo Angelin; Mats Rudling
Molecular aspects of human lipid metabolism.
European journal of clinical nutrition 1992;46(3):153-60.
1992: A Hedman; Bo Angelin; A Arvidsson; R Dahlqvist
Digoxin-interactions in man: spironolactone reduces renal but not biliary digoxin clearance.
European journal of clinical pharmacology 1992;42(5):481-5.
1992: J Sjövall; Gunnar Alván; J E Akerlund; Jan-Olof Svensson; Gilles Paintaud; C E Nord; Bo Angelin
Dose-dependent absorption of amoxicillin in patients with an ileostomy.
European journal of clinical pharmacology 1992;43(3):277-81.
1992: P T Larsson; G Olsson; Bo Angelin; E Granström; G Hansson; Paul Hjemdahl
Metoprolol does not reduce platelet aggregability during sympatho-adrenal stimulation.
European journal of clinical pharmacology 1992;42(4):413-21.
1992: B Nyberg; Bo Angelin; K Einarsson
Somatostatin does not block the effect of vasoactive intestinal peptide on bile secretion in man.
European journal of clinical investigation 1992;22(1):60-6.
1991: S Sahlin; J Ahlberg; Bo Angelin; E Reihnér; K Einarsson
Nucleation time of gall bladder bile in gall stone patients: influence of bile acid treatment.
Gut 1991;32(12):1554-7.
1991: Dagny Ståhlberg; E Reihnér; Bo Angelin; K Einarsson
Interruption of the enterohepatic circulation of bile acids stimulates the esterification rate of cholesterol in human liver.
Journal of lipid research 1991;32(9):1409-15.
1991: M Eriksson; Bo Angelin; P Henriksson; S Ericsson; S Vitols; Lars Berglund
Metabolism of lipoprotein remnants in humans. Studies during intestinal infusion of fat and cholesterol in subjects with varying expression of the low density lipoprotein receptor.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(4):827-37.
1991: A Hedman; Bo Angelin; A Arvidsson; R Dahlqvist
No effect of probenecid on the renal and biliary clearances of digoxin in man.
British journal of clinical pharmacology 1991;32(1):63-7.
1991: B Odman; S Ericsson; M Lindmark; Lars Berglund; Bo Angelin
Gemfibrozil in familial combined hyperlipidaemia: effect of added low-dose cholestyramine on plasma and biliary lipids.
European journal of clinical investigation 1991;21(3):344-9.
1991: Dagny Ståhlberg; Bo Angelin; K Einarsson
Age-related changes in the metabolism of cholesterol in rat liver microsomes.
Lipids 1991;26(5):349-52.
1991: J E Akerlund; E Reihnér; Bo Angelin; Mats Rudling; S Ewerth; Ingemar Björkhem; K Einarsson
Hepatic metabolism of cholesterol in Crohn's disease. Effect of partial resection of ileum.
Gastroenterology 1991;100(4):1046-53.
1991: M Carrella; S Ericsson; C Del Piano; Bo Angelin; K Einarsson
Effect of cholestyramine treatment on biliary lipid secretion rates in normolipidaemic men.
Journal of internal medicine 1991;229(3):241-6.
1991: A Hedman; Bo Angelin; A Arvidsson; O Beck; R Dahlqvist; B Nilsson; M Olsson; Karin Schenck-Gustafsson
Digoxin-verapamil interaction: reduction of biliary but not renal digoxin clearance in humans.
Clinical pharmacology and therapeutics 1991;49(3):256-62.
1991: S Ericsson; M Eriksson; S Vitols; K Einarsson; Lars Berglund; Bo Angelin
Influence of age on the metabolism of plasma low density lipoproteins in healthy males.
The Journal of clinical investigation 1991;87(2):591-6.
1991: K Einarsson; S Ericsson; S Ewerth; E Reihnér; Mats Rudling; Dagny Ståhlberg; Bo Angelin
Bile acid sequestrants: mechanisms of action on bile acid and cholesterol metabolism.
European journal of clinical pharmacology 1991;40 Suppl 1():S53-8.
1991: Dagny Ståhlberg; E Reihnér; S Ewerth; K Einarsson; Bo Angelin
Effects of bezafibrate on hepatic cholesterol metabolism.
European journal of clinical pharmacology 1991;40 Suppl 1():S33-6.
1991: S Sahlin; P Thyberg; J Ahlberg; Bo Angelin; K Einarsson
Distribution of cholesterol between vesicles and micelles in human gallbladder bile: influence of treatment with chenodeoxycholic acid and ursodeoxycholic acid.
Hepatology (Baltimore, Md.) 1991;13(1):104-10.
1990: Olov Wiklund; Bo Angelin; Gunnar Fager; M Eriksson; Sven-Olof Olofsson; Lars Berglund; T Lindén; A Sjöberg; Göran Bondjers
Treatment of familial hypercholesterolaemia: a controlled trial of the effects of pravastatin or cholestyramine therapy on lipoprotein and apolipoprotein levels.
Journal of internal medicine 1990;228(3):241-7.
1990: P T Larsson; Paul Hjemdahl; G Olsson; Bo Angelin; G Hornstra
Platelet aggregability in humans: contrasting in vivo and in vitro findings during sympatho-adrenal activation and relationship to serum lipids.
European journal of clinical investigation 1990;20(4):398-405.
1990: P T Larsson; B Wiman; G Olsson; Bo Angelin; Paul Hjemdahl
Influence of metoprolol treatment on sympatho-adrenal activation of fibrinolysis.
Thrombosis and haemostasis 1990;63(3):482-7.
1990: S Ericsson; M Eriksson; Bo Angelin
Biliary lipids in familial combined hyperlipidaemia: effects of acipimox therapy.
European journal of clinical investigation 1990;20(3):261-5.
1990: S Vitols; Bo Angelin; S Ericsson; G Gahrton; G Juliusson; M Masquelier; C Paul; Curt Peterson; Mats Rudling; K Söderberg-Reid
Uptake of low density lipoproteins by human leukemic cells in vivo: relation to plasma lipoprotein levels and possible relevance for selective chemotherapy.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2598-602.
1990: Bo Angelin; B Leijd; R Hultcrantz; K Einarsson
Increased turnover of very low density lipoprotein triglyceride during treatment with cholestyramine in familial hypercholesterolaemia.
Journal of internal medicine 1990;227(3):201-6.
1990: Mats Rudling; Bo Angelin; C O Peterson; V P Collins
Low density lipoprotein receptor activity in human intracranial tumors and its relation to the cholesterol requirement.
Cancer research 1990;50(3):483-7.
1990: A Hedman; Bo Angelin; A Arvidsson; R Dahlqvist; B Nilsson
Interactions in the renal and biliary elimination of digoxin: stereoselective difference between quinine and quinidine.
Clinical pharmacology and therapeutics 1990;47(1):20-6.
1989: P Henriksson; M Eriksson; S Ericsson; Mats Rudling; R Stege; Lars Berglund; Bo Angelin
Hypocholesterolaemia and increased elimination of low-density lipoproteins in metastatic cancer of the prostate.
Lancet 1989;2(8673):1178-80.
1989: S Ahnve; Bo Angelin; O Edhag; Lars Berglund
Early determination of serum lipids and apolipoproteins in acute myocardial infarction: possibility for immediate intervention.
Journal of internal medicine 1989;226(5):297-301.
1989: P Henriksson; K Einarsson; A Eriksson; U Kelter; Bo Angelin
Estrogen-induced gallstone formation in males. Relation to changes in serum and biliary lipids during hormonal treatment of prostatic carcinoma.
The Journal of clinical investigation 1989;84(3):811-6.
1989: M Eriksson; Lars Berglund; Mats Rudling; P Henriksson; Bo Angelin
Effects of estrogen on low density lipoprotein metabolism in males. Short-term and long-term studies during hormonal treatment of prostatic carcinoma.
The Journal of clinical investigation 1989;84(3):802-10.
1989: R Löfberg; Bo Angelin; K Einarsson; N Gabrielsson; L Ost
Unsatisfactory effect of cyclosporin A treatment in Crohn's disease: a report of five cases.
Journal of internal medicine 1989;226(3):157-61.
1989: Dagny Ståhlberg; Bo Angelin; K Einarsson
Effects of treatment with clofibrate, bezafibrate, and ciprofibrate on the metabolism of cholesterol in rat liver microsomes.
Journal of lipid research 1989;30(7):953-8.
1989: K Einarsson; L Benthin; S Ewerth; G Hellers; Dagny Ståhlberg; Bo Angelin
Studies on acyl-coenzyme A: cholesterol acyltransferase activity in human liver microsomes.
Journal of lipid research 1989;30(5):739-46.
1989: Lars Berglund; Ingemar Björkhem; Bo Angelin; K Einarsson
Activation of rat liver cytosolic phosphatidic acid phosphatase by nucleoside diphosphates.
Biochimica et biophysica acta 1989;1002(3):382-7.
1989: M Eriksson; B Berg; Lars Berglund; B Lantz; Bo Angelin
Lipid lowering in severe familial hypercholesterolaemia: efficacy and safety of a new regenerating system for selective apheresis of apolipoprotein B-containing lipoproteins.
Journal of internal medicine 1989;225(1):29-34.
1989: Bo Angelin
Effect of thiazide treatment on biliary lipid composition in healthy volunteers.
European journal of clinical pharmacology 1989;37(1):95-6.
1988: S Sahlin; A Danielsson; Bo Angelin; E Reihnér; R Henriksson; K Einarsson
Mucin in gall bladder bile of gall stone patients: influence of treatment with chenodeoxycholic acid and ursodeoxycholic acid.
Gut 1988;29(11):1506-10.
1988: Bo Angelin
Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in mouse peritoneal macrophages.
The Biochemical journal 1988;255(2):529-34.
1988: Bo Angelin; K Einarsson; B Leijd; L Wallentin
Plasma cholesterol esterification rate in hyperlipoproteinaemia: relation to cholesterol elimination.
Scandinavian journal of clinical and laboratory investigation 1988;48(5):481-7.
1988: Ingemar Björkhem; O Breuer; Bo Angelin; S A Wikström
Assay of unesterified cholesterol-5,6-epoxide in human serum by isotope dilution mass spectrometry. Levels in the healthy state and in hyperlipoproteinemia.
Journal of lipid research 1988;29(8):1031-8.
1988: S Sahlin; J Ahlberg; Bo Angelin; S Ewerth; K Nilsell; E Reihnér; K Einarsson
Occurrence of cholesterol monohydrate crystals in gallbladder and hepatic bile in man: influence of bile acid treatment.
European journal of clinical investigation 1988;18(4):386-90.
1988: A Arvidsson; B Leijd; C E Nord; Bo Angelin
Interindividual variability in biliary excretion of ceftriaxone: effects on biliary lipid metabolism and on intestinal microflora.
European journal of clinical investigation 1988;18(3):261-6.
1988: Bo Angelin
Bile acid metabolism in heterozygous familial hypercholesterolaemia: a study comparing affected and unaffected siblings of four kindreds.
European journal of clinical investigation 1988;18(2):153-61.
1987: K Einarsson; Bo Angelin; C Johansson
Biliary lipid metabolism in chronic pancreatitis: influence of steatorrhoea.
Gut 1987;28(11):1495-9.
1987: Ingemar Björkhem; T Miettinen; E Reihnér; S Ewerth; Bo Angelin; K Einarsson
Correlation between serum levels of some cholesterol precursors and activity of HMG-CoA reductase in human liver.
Journal of lipid research 1987;28(10):1137-43.
1987: M Eriksson; Bo Angelin
Bezafibrate therapy and biliary lipids: effects of short-term and long-term treatment in patients with various forms of hyperlipoproteinaemia.
European journal of clinical investigation 1987;17(5):396-401.
1987: Ingemar Björkhem; E Reihnér; Bo Angelin; S Ewerth; J E Akerlund; K Einarsson
On the possible use of the serum level of 7 alpha-hydroxycholesterol as a marker for increased activity of the cholesterol 7 alpha-hydroxylase in humans.
Journal of lipid research 1987;28(8):889-94.
1987: Bo Angelin; A Arvidsson; R Dahlqvist; A Hedman; Karin Schenck-Gustafsson
Quinidine reduces biliary clearance of digoxin in man.
European journal of clinical investigation 1987;17(3):262-5.
1986: K Einarsson; Bo Angelin; S Ewerth; K Nilsell; I Björkhem
Bile acid synthesis in man: assay of hepatic microsomal cholesterol 7 alpha-hydroxylase activity by isotope dilution-mass spectrometry.
Journal of lipid research 1986;27(1):82-8.
1985: K Einarsson; J Ahlberg; Bo Angelin; I Björkhem; S Ewerth
Portal venous bile acids in cholesterol gallstone disease: effect of treatment with chenodeoxycholic and cholic acids.
Hepatology (Baltimore, Md.) 1985;5(4):661-5.
1985: S Ewerth; Bo Angelin; K Einarsson; K Nilsell; I Björkhem
Serum concentrations of ursodeoxycholic acid in portal venous and systemic venous blood of fasting humans as determined by isotope dilution-mass spectrometry.
Gastroenterology 1985;88(1 Pt 1):126-33.