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Martin Fey

Research Profile

Physiology

Chemicals & Drugs

Procedures

Disorders

Anatomy

Genes & Molecular Sequences

Genes, Tumor Suppressor

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Publications

TOP 3
Elena A Federzoni; Martin F Fey; Magali Humbert; Elisabeth Oppliger Leibundgut; Bruce E Torbett; Gerhard Behre; Peter J M Valk; Mario P Tschan
The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients.
Magali Humbert; Michaela Medová; Yitzhak Zimmer; Daniel M Aebersold; Friedhelm Bladt; Andree Blaukat; Martin F Fey; Mario P Tschan
Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.
Magali Humbert; Chantal Mueller; Martin F Fey; Mario P Tschan
Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells.

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2013: Elena A Federzoni; Martin F Fey; Magali Humbert; Elisabeth Oppliger Leibundgut; Bruce E Torbett; Gerhard Behre; Peter J M Valk; Mario P Tschan
The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients.
British journal of haematology 2013;160(6):855-9.
2013: Magali Humbert; Michaela Medová; Yitzhak Zimmer; Daniel M Aebersold; Friedhelm Bladt; Andree Blaukat; Martin F Fey; Mario P Tschan
Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.
Biochemical and biophysical research communications 2013;431(2):264-9.
2012: Magali Humbert; Chantal Mueller; Martin F Fey; Mario P Tschan
Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells.
Leukemia research 2012;36(12):1552-6.
2012: Elena A Federzoni; Martin F Fey; Torsten Haferlach; Bob Löwenberg; Bruce E Torbett; Peter J M Valk; Mario P Tschan
PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells.
Blood 2012;119(21):4963-70.
2012: Jasmin Batliner; Emanuel Buehrer; Elena A Federzoni; Martin F Fey; Mathias Jenal; Andreas Tobler; Bruce E Torbett; Mario P Tschan
Transcriptional regulation of MIR29B by PU.1 (SPI1) and MYC during neutrophil differentiation of acute promyelocytic leukaemia cells.
British journal of haematology 2012;157(2):270-4.
2012: Souzan Salemi; Mihai A Constantinescu; Martin F Fey; Shida Yousefi; Hans-Uwe Simon
Autophagy is required for self-renewal and differentiation of adult human stem cells.
Cell research 2012;22(2):432-5.
2012: Anna M Schläfli; Bruce E Torbett; Martin F Fey; Mario P Tschan
BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation.
Experimental hematology & oncology 2012;1(1):25.
2012: Henning Burmeister; Martin F Fey; Stefan Aebi; Cristina Studer; Oliver Gautschi
Adherence to ESMO clinical recommendations for prophylaxis of chemotherapy-induced nausea and vomiting.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2012;20(1):141-7.
2011: Magali Humbert; Judith Laedrach; Elisabeth Oppliger Leibundgut; Deborah Shan; Andreas Tobler; GM Baerlocher; Martin F Fey; Veronika Halter; Mario P Tschan
Deregulated expression of Kruppel-like factors in acute myeloid leukemia.
Leukemia research 2011;35(7):909-13.
2011: Jasmin Batliner; Maria Michela Mancarelli; Mathias Jenal; Venkateshwar A Reddy; Martin F Fey; Bruce E Torbett; Mario P Tschan
CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation.
Molecular immunology 2011;48(4):714-9.
2010: Adrian Britschgi; Hans-Uwe Simon; Andreas Tobler; Martin F Fey; Mario P Tschan
Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2.
British journal of haematology 2010;149(1):55-64.
2010: Mario P Tschan; Deborah Shan; Judith Laedrach; Marianne Eyholzer; Elisabeth Oppliger Leibundgut; Gabriela M Baerlocher; Andreas Tobler; Deborah Stroka; Martin F Fey
NDRG1/2 expression is inhibited in primary acute myeloid leukemia.
Leukemia research 2010;34(3):393-8.
2009: N Andina; Sébastien Conus; E M Schneider; Martin F Fey; Hans-Uwe Simon
Induction of Bim limits cytokine-mediated prolonged survival of neutrophils.
Cell death and differentiation 2009;16(9):1248-55.
2009: Olivia Pagani; Karen N Price; Richard D Gelber; Monica Castiglione-Gertsch; Stig B Holmberg; Jurij Lindtner; Beat Thürlimann; John Collins; Martin F Fey; Alan Coates; Aron Goldhirsch
Patterns of recurrence of early breast cancer according to estrogen receptor status: a therapeutic target for a quarter of a century.
Breast cancer research and treatment 2009;117(2):319-24.
2009: Olivia Pagani; Shari Gelber; Edda Simoncini; Monica Castiglione-Gertsch; Karen N Price; Richard D Gelber; Stig B Holmberg; Diana Crivellari; John Collins; Jurij Lindtner; Beat Thürlimann; Martin F Fey; Elizabeth Margaret Murray; John Forbes; Alan Coates; Aron Goldhirsch
Is adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? International Breast Cancer Study Group Trials VII and 12-93.
Breast cancer research and treatment 2009;116(3):491-500.
2009: Mathias Jenal; Emmanuelle Trinh; Christian Britschgi; Adrian Britschgi; Vincent Roh; Stephan A Vorburger; Andreas Tobler; Dominique Leprince; Martin F Fey; Kristian Helin; Mario P Tschan
The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1.
Molecular cancer research : MCR 2009;7(6):916-22.
2009: Julia Bohlius; Kurt Schmidlin; Corinne Brillant; Guido Schwarzer; Sven Trelle; Jerome Seidenfeld; Marcel Zwahlen; Mike Clarke; Olaf Weingart; Sabine Kluge; Margaret Piper; Dirk Rades; David P Steensma; Benjamin Djulbegovic; Martin F Fey; ISABELLE RAY COQUARD; Mitchell Machtay; Volker Moebus; Gillian Thomas; Michael Untch; Martin Schumacher; Matthias Egger; Andreas Engert
Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials.
Lancet 2009;373(9674):1532-42.
2009: Christian Britschgi; Martin F Fey
Tumor suppressor genes in myeloid differentiation and leukemogenesis.
Future oncology (London, England) 2009;5(2):245-57.
2009: Julia Bohlius; Kurt Schmidlin; Corinne Brillant; Guido Schwarzer; Sven Trelle; Jerome Seidenfeld; Marcel Zwahlen; Mike Clarke; Olaf Weingart; Sabine Kluge; Margaret Piper; Maryann Napoli; Dirk Rades; David Steensma; Benjamin Djulbegovic; Martin F Fey; ISABELLE RAY COQUARD; Volker Moebus; Gillian Thomas; Michael Untch; Martin Schumacher; Matthias Egger; Andreas Engert
Erythropoietin or Darbepoetin for patients with cancer--meta-analysis based on individual patient data.
Cochrane database of systematic reviews (Online) 2009;(3):CD007303.
2008: A Britschgi; E Trinh; M Rizzi; M Jenal; A Ress; Andreas Tobler; Martin F Fey; K Helin; Mario P Tschan
DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function.
Oncogene 2008;27(43):5706-16.
2008: Martin F Fey
New insights into molecular mechanisms of haematological malignancies.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19 Suppl 5():v59-62.
2008: Mario P Tschan; V A Reddy; A Ress; G Arvidsson; Martin F Fey; Bruce E Torbett
PU.1 binding to the p53 family of tumor suppressors impairs their transcriptional activity.
Oncogene 2008;27(24):3489-93.
2008: Christian Britschgi; Mathias Jenal; Mattia Rizzi; Beatrice U Mueller; Bruce E Torbett; Anne-Catherine Andres; Andreas Tobler; Martin F Fey; Mario P Tschan
HIC1 tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation.
British journal of haematology 2008;141(2):179-87.
2008: Dirk H Westermann; Hubert Schefer; George N Thalmann; Evanthia Karamitopoulou-Diamantis; Martin F Fey; Urs E Studer
Long-term followup results of 1 cycle of adjuvant bleomycin, etoposide and cisplatin chemotherapy for high risk clinical stage I nonseminomatous germ cell tumors of the testis.
The Journal of urology 2008;179(1):163-6.
2008: G Kostylina; D Simon; Martin F Fey; Shida Yousefi; H U Simon
Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A).
Cell death and differentiation 2008;15(1):134-42.
2007: Mattia Rizzi; Mario P Tschan; Christian Britschgi; Adrian Britschgi; Barbara Hügli; Tobias J Grob; Nicolas Leupin; Beatrice U Mueller; Hans-Uwe Simon; Andrew Ziemiecki; Bruce E Torbett; Martin F Fey; Andreas Tobler
The death-associated protein kinase 2 is up-regulated during normal myeloid differentiation and enhances neutrophil maturation in myeloid leukemic cells.
Journal of leukocyte biology 2007;81(6):1599-608.
2007: Per Karlsson; Bernard F Cole; Karen N Price; Alan Coates; Monica Castiglione-Gertsch; Barry A Gusterson; Elizabeth Margaret Murray; Jurij Lindtner; John P Collins; Stig B Holmberg; Martin F Fey; Beat Thürlimann; Diana Crivellari; John Forbes; Richard D Gelber; Aron Goldhirsch; Arne Wallgren
The role of the number of uninvolved lymph nodes in predicting locoregional recurrence in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(15):2019-26.
2007: Martin F Fey
Normal and malignant hematopoiesis.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18 Suppl 1():i9-i13.
2007: Martin F Fey
Salient features of hematological diseases.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18 Suppl 1():i54-i64.
2006: Sibylla Martinelli; G Kostylina; Verena Niggli; C Baumann; Martin F Fey; H-G Wendel; Scott W Lowe; Shida Yousefi; Hans-Uwe Simon
Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils.
Oncogene 2006;25(52):6915-23.
2006: Nicolas Leupin; Alexandre Kuhn; Barbara Hügli; Tobias J Grob; Rolf Jaggi; Andreas Tobler; Mauro Delorenzi; Martin F Fey
Gene expression profiling reveals consistent differences between clinical samples of human leukaemias and their model cell lines.
British journal of haematology 2006;135(4):520-3.
2006: Bernhard C Pestalozzi; David Zahrieh; Karen N Price; Stig B Holmberg; Jurij Lindtner; John Collins; Diana Crivellari; Martin F Fey; Elizabeth Margaret Murray; Olivia Pagani; Edda Simoncini; Monica Castiglione-Gertsch; Richard D Gelber; Alan Coates; Aron Goldhirsch
Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(6):935-44.
2006: Beatrice U Mueller; Thomas Pabst; José Fos; Vibor Petkovic; Martin F Fey; Norio Asou; Ulrich Buergi; Daniel G Tenen
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression.
Blood 2006;107(8):3330-8.
2006: Beatrice U Mueller; A U Buerger; Max Solenthaler; E M Garamvoelgyi; Elisabeth Oppliger Leibundgut; Martin F Fey; T Pabst
Pleural tumors as sole primary manifestation of acute promyelocytic leukemia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(4):722-3.
2006: C Britschgi; M Rizzi; Tobias J Grob; Mario P Tschan; Barbara Hügli; V A Reddy; A-C Andres; Bruce E Torbett; Andreas Tobler; Martin F Fey
Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1.
Oncogene 2006;25(14):2030-9.
2006: Jean-François Dufour; Martin F Fey
What is the current treatment of PTLD after liver transplantation?
Journal of hepatology 2006;44(1):23-6.
2005: Günther Gruber; Marco Bonetti; M Laura Nasi; Karen N Price; Monica Castiglione-Gertsch; Carl-Magnus Rudenstam; Stig B Holmberg; Jurij Lindtner; Rastko Golouh; John Collins; Diana Crivellari; Antonino Carbone; Beat Thürlimann; Edda Simoncini; Martin F Fey; Richard D Gelber; Alan Coates; Aron Goldhirsch
Prognostic value of extracapsular tumor spread for locoregional control in premenopausal patients with node-positive breast cancer treated with classical cyclophosphamide, methotrexate, and fluorouracil: long-term observations from International Breast Cancer Study Group Trial VI.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(28):7089-97.
2005: O Hopfer; D Zwahlen; Martin F Fey; Stefan Aebi
The Notch pathway in ovarian carcinomas and adenomas.
British journal of cancer 2005;93(6):709-18.
2005: Daniel Helbling; Beatrice U Mueller; Nikolai A Timchenko; Julian Schardt; Myriam Eyer; David R Betts; Martine Jotterand; Sandrine Meyer-Monard; Martin F Fey; Thomas Pabst
CBFB-SMMHC is correlated with increased calreticulin expression and suppresses the granulocytic differentiation factor CEBPA in AML with inv(16).
Blood 2005;106(4):1369-75.
2005: Marco Colleoni; David Zahrieh; Richard D Gelber; Stig B Holmberg; Jan E Mattsson; Carl-Magnus Rudenstam; Jurij Lindtner; Darja Erzen; Raymond Snyder; John Collins; Martin F Fey; Beat Thürlimann; Diana Crivellari; Elizabeth Margaret Murray; Caesar Mendiola; Olivia Pagani; Monica Castiglione-Gertsch; Alan Coates; Karen Price; Aron Goldhirsch
Site of primary tumor has a prognostic role in operable breast cancer: the international breast cancer study group experience.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(7):1390-400.
2005: Marianne Bienz; Madleina Ludwig; Elisabeth Oppliger Leibundgut; Beatrice U Mueller; Daniel Ratschiller; Max Solenthaler; Martin F Fey; Thomas Pabst
Risk assessment in patients with acute myeloid leukemia and a normal karyotype.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(4):1416-24.
2005: Michele Ghielmini; Shu-Fang Hsu Schmitz; Sergio B Cogliatti; Francesco Bertoni; Ursula Waltzer; Martin F Fey; Daniel C Betticher; Hubert Schefer; Gabriella Pichert; Rolf Stahel; Nicolas Ketterer; Mario Bargetzi; Thomas Cerny
Effect of single-agent rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: a study of the Swiss Group for Clinical Cancer Research (SAKK).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(4):705-11.
2005: Martin F Fey; richard greil; L M Jost
ESMO Minimum Clinical Recommendations for the diagnosis, treatment and follow-up of acute myeloblastic leukemia (AML) in adult patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16 Suppl 1():i48-9.
2004: Martin F Fey
Clinical trial design in oncology: selection of patients.
The lancet oncology 2004;5(12):760.
2004: Jürg Bernhard; David Zahrieh; Alan Coates; Richard D Gelber; Monica Castiglione-Gertsch; Elizabeth Margaret Murray; John Forbes; Lucien Perey; John Collins; R Snyder; Carl-Magnus Rudenstam; Diana Crivellari; Andrea Veronesi; Beat Thürlimann; Martin F Fey; Karen N Price; Aron Goldhirsch; Christoph Hürny
Quantifying trade-offs: quality of life and quality-adjusted survival in a randomised trial of chemotherapy in postmenopausal patients with lymph node-negative breast cancer.
British journal of cancer 2004;91(11):1893-901.
2004: Sibylla Martinelli; Mirjana Urosevic-Maiwald; Arezoo Daryadel; Patrick A Oberholzer; Christa Baumann; Martin F Fey; Reinhard Dummer; Hans-Uwe Simon; Shida Yousefi
Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation.
The Journal of biological chemistry 2004;279(42):44123-32.
2004: Daniel Helbling; Beatrice U Mueller; Nikolai A Timchenko; Anne Hagemeijer; Martine Jotterand; Sandrine Meyer-Monard; Andrew Lister; Janet D Rowley; Barbara Huegli; Martin F Fey; Thomas Pabst
The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(36):13312-7.
2004: Michele Ghielmini; Shu-Fang Hsu Schmitz; Sergio B Cogliatti; Gabriella Pichert; Jörg Hummerjohann; Ursula Waltzer; Martin F Fey; Daniel C Betticher; Giovanni Martinelli; Fedro Alessandro Peccatori; Urs Hess; Emanuele Zucca; Roger Stupp; Tibor J Kovacsovics; Claudine Helg; Andreas Lohri; Mario Bargetzi; Daniel Vorobiof; Thomas Cerny
Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly x 4 schedule.
Blood 2004;103(12):4416-23.
2004: Nicolas Leupin; Alexander Lüthi; Urban Novak; Tobias J Grob; Barbara Hügli; Hans U Graber; Martin F Fey; Andreas Tobler
P73 status in B-cell chronic lymphocytic leukaemia.
Leukemia & lymphoma 2004;45(6):1205-7.
2004: Gilles Berclaz; Sigui Li; Karen N Price; Alan Coates; Monica Castiglione-Gertsch; Carl-Magnus Rudenstam; Stig B Holmberg; Jurij Lindtner; D Erien; John Collins; R Snyder; Beat Thürlimann; Martin F Fey; Caesar Mendiola; I Dudley Werner; Edda Simoncini; Diana Crivellari; Richard D Gelber; Aron Goldhirsch
Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(6):875-84.
2004: Frank Altznauer; Sibylla Martinelli; Shida Yousefi; Christine Thürig; Inès Schmid; Edward M Conway; Martin H Schöni; Peter Vogt; Christoph Mueller; Martin F Fey; Uwe Zangemeister-Wittke; Hans-Uwe Simon
Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils.
The Journal of experimental medicine 2004;199(10):1343-54.
2004: Urban Novak; Andreas Tobler; Martin F Fey
Allelotyping in B-cell chronic lymphocytic leukemia (B-CLL).
Leukemia & lymphoma 2004;45(5):887-96.
2004: Martin F Fey
Genomics and proteomics: expression arrays in clinical oncology.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15 Suppl 4():iv163-5.
2003: Diana Crivellari; Karen Price; Richard D Gelber; Monica Castiglione-Gertsch; Carl-Magnus Rudenstam; Jurij Lindtner; Martin F Fey; Hans-Jörg Senn; Alan Coates; John Collins; Aron Goldhirsch
Adjuvant endocrine therapy compared with no systemic therapy for elderly women with early breast cancer: 21-year results of International Breast Cancer Study Group Trial IV.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(24):4517-23.
2003: Catherine Mengis; Stefan Aebi; Andreas Tobler; Werner Dähler; Martin F Fey
Assessment of differences in patient populations selected for excluded from participation in clinical phase III acute myelogenous leukemia trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(21):3933-9.
2003: Mario P Tschan; Kimberlee M Fischer; Vivian S Fung; Farzaneh Pirnia; Markus M Borner; Martin F Fey; Andreas Tobler; Bruce E Torbett
Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns.
The Journal of biological chemistry 2003;278(44):42750-60.
2003: Martin F Fey
ESMO Minimum Clinical Recommendations for diagnosis, treatment and follow-up of acute myeloblastic leukaemia (AML) in adult patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(8):1161-2.
2003: Nicolas Leupin; Bruno Cenni; Urban Novak; Barbara Hügli; Hans U Graber; Andreas Tobler; Martin F Fey
Disparate expression of the PTEN gene: a novel finding in B-cell chronic lymphocytic leukaemia (B-CLL).
British journal of haematology 2003;121(1):97-100.
2002: Albert Von Rohr; Shu-Fang Hsu Schmitz; André Tichelli; Urs Hess; D Piguet; Marion Wernli; N Frickhofen; G Konwalinka; Gilbert B Zulian; Michele Ghielmini; Beatrice Rufener; C Racine; Martin F Fey; Thomas Cerny; Daniel C Betticher; Andreas Tobler
Treatment of hairy cell leukemia with cladribine (2-chlorodeoxyadenosine) by subcutaneous bolus injection: a phase II study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13(10):1641-9.
2002: Urban Novak; Elisabeth Oppliger Leibundgut; Jörg Hager; Dominique Mühlematter; Martine Jotterand; Celine Besse; Nicolas Leupin; Daniel Ratschiller; Jeanette Papp; Gina Kearsey; Stefan Aebi; Hans U Graber; Rolf Jaggi; Jean-Marc Lüthi; Sandrine Meyer-Monard; Mark Lathrop; Andreas Tobler; Martin F Fey
A high-resolution allelotype of B-cell chronic lymphocytic leukemia (B-CLL).
Blood 2002;100(5):1787-94.
2002: Tobias J Grob; Martin F Fey; Andreas Tobler
The two faces of p73.
Cell death and differentiation 2002;9(3):229-30.
2002: Martin F Fey
The impact of chip technology on cancer medicine.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13 Suppl 4():109-13.
2001: Tobias J Grob; Urban Novak; Carine Maisse; Daniela Barcaroli; Alexander Lüthi; Farzaneh Pirnia; Barbara Hügli; Hans U Graber; Vincenzo de Laurenzi; Martin F Fey; Gerry Melino; Andreas Tobler
Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.
Cell death and differentiation 2001;8(12):1213-23.
2001: Mario P Tschan; S Vonlanthen; JF Cajot; UR Peters; E Oppliger; Daniel C Betticher; Wendell G Yarbrough; Martin F Fey; Andreas Tobler
Different p16INK4a and p14ARF expression patterns in acute myeloid leukaemia and normal blood leukocytes.
Leukemia & lymphoma 2001;42(5):1077-87.
2001: Urban Novak; Tobias J Grob; Gökben Baskaynak; UR Peters; Stefan Aebi; D Zwahlen; Mario P Tschan; Karl-Anton Kreuzer; Elisabeth Oppliger Leibundgut; JF Cajot; Andreas Tobler; Martin F Fey
Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(7):981-6.
2001: J Roos; I Hennig; J Schwaller; J Zbären; R Dummer; G Burg; Andreas Tobler; L Virgilio; C M Croce; Martin F Fey; Bettina Borisch
Expression of TCL1 in hematologic disorders.
Pathobiology : journal of immunopathology, molecular and cellular biology 2001;69(2):59-66.
2000: Mario P Tschan; Tobias J Grob; UR Peters; V D Laurenzi; B Huegli; Karl-Anton Kreuzer; Christian A Schmidt; Gerry Melino; Martin F Fey; Andreas Tobler; JF Cajot
Enhanced p73 expression during differentiation and complex p73 isoforms in myeloid leukemia.
Biochemical and biophysical research communications 2000;277(1):62-5.
2000: S Balli; Martin F Fey; Willy Hänggi; D Zwahlen; Gilles Berclaz; Ekkehard Dreher; Stefan Aebi
Ovarian cancer. an institutional review of patterns of care, health insurance and prognosis.
European journal of cancer (Oxford, England : 1990) 2000;36(16):2061-8.
2000: D Zwahlen; Mario P Tschan; Tobias J Grob; UR Peters; D Fink; W Haenggi; Hans J Altermatt; JF Cajot; Andreas Tobler; Martin F Fey; Stefan Aebi
Differential expression of p73 splice variants and protein in benign and malignant ovarian tumours.
International journal of cancer. Journal international du cancer 2000;88(1):66-70.
2000: A Gähler; T Stallmach; J Schwaller; Martin F Fey; Andreas Tobler
Interleukin-8 expression by fetal and neonatal pulmonary cells in hyaline membrane disease and amniotic infection.
Pediatric research 2000;48(3):299-303.
2000: Thomas Pabst; UR Peters; Marianne Tinguely; J Schwaller; Mario P Tschan; Stefan Aebi; S Vonlanthen; Bettina Borisch; Daniel C Betticher; A Zimmermann; Andreas Tobler; Martin F Fey
Divergent expression of cyclin-dependent kinase inhibitors (CKI) and p14ARF/p16 beta in non-Hodgkin's lymphomas and chronic lymphocytic leukemia.
Leukemia & lymphoma 2000;37(5-6):639-48.
2000: Rudolf Morant; Jürg Bernhard; Rudolf Maibach; Markus M Borner; Martin F Fey; Beat Thürlimann; Emanuel Jacky; Felix B Trinkler; J Bauer; G Zulian; Silvia Hanselmann; Christoph Hürny; Franz Hering
Response and palliation in a phase II trial of gemcitabine in hormone-refractory metastatic prostatic carcinoma. Swiss Group for Clinical Cancer Research (SAKK).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(2):183-8.
1999: U Hasse; Marianne Tinguely; Elisabeth Oppliger Leibundgut; JF Cajot; A M Garvin; A Tobler; B Borisch; Martin F Fey
Clonal loss of heterozygosity in microdissected Hodgkin and Reed-Sternberg cells.
Journal of the National Cancer Institute 1999;91(18):1581-3.
1999: Christoph Rochlitz; Andreas Lohri; M Bacchi; M Schmidt; S Nagel; Markus Fopp; Martin F Fey; Richard Herrmann; A Neubauer
Axl expression is associated with adverse prognosis and with expression of Bcl-2 and CD34 in de novo acute myeloid leukemia (AML): results from a multicenter trial of the Swiss Group for Clinical Cancer Research (SAKK).
Leukemia 1999;13(9):1352-8.
1999: Mario P Tschan; UR Peters; JF Cajot; Daniel C Betticher; Martin F Fey; Andreas Tobler
The cyclin-dependent kinase inhibitors p18INK4c and p19INK4d are highly expressed in CD34+ progenitor and acute myeloid leukaemic cells but not in normal differentiated myeloid cells.
British journal of haematology 1999;106(3):644-51.
1999: Jürg Bernhard; Beat Thürlimann; Shu-Fang Hsu Schmitz; Monica Castiglione-Gertsch; Franco Cavalli; Rudolf Morant; Martin F Fey; Hervé Bonnefoi; Aron Goldhirsch; Christoph Hürny
Defining clinical benefit in postmenopausal patients with breast cancer under second-line endocrine treatment: does quality of life matter?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(6):1672-9.
1999: Jürg Bernhard; Monica Castiglione-Gertsch; Shu-Fang Hsu Schmitz; Beat Thürlimann; Franco Cavalli; Rudolf Morant; Martin F Fey; Hervé Bonnefoi; Aron Goldhirsch; Christoph Hürny
Quality of life in postmenopausal patients with breast cancer after failure of tamoxifen: formestane versus megestrol acetate as second-line hormonal treatment. Swiss Group for Clinical Cancer Research (SAKK).
European journal of cancer (Oxford, England : 1990) 1999;35(6):913-20.
1999: D Zahnd; Stefan Aebi; S Rusterholz; Martin F Fey; Markus M Borner
A randomized crossover trial assessing patient preference for two different types of portable infusion-pump devices.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(6):727-9.
1999: B Bättig; E Mueller-Garamvoelgyi; Sergio B Cogliatti; Ulrico Schmid; Andreas Kappeler; Thomas Cerny; Jean A Laissue; Martin F Fey
T-cell-rich B-cell non-Hodgkin's lymphoma mimicking Hodgkin's disease.
Leukemia & lymphoma 1999;33(3-4):393-8.
1999: Dominik Böhlen; Markus M Borner; RW Sonntag; Martin F Fey; Urs E Studer
Long-term results following adjuvant chemotherapy in patients with clinical stage I testicular nonseminomatous malignant germ cell tumors with high risk factors.
The Journal of urology 1999;161(4):1148-52.
1999: UR Peters; U Hasse; E Oppliger; Mario P Tschan; ST Ong; Feyruz V Rassool; Bettina Borisch; Andreas Tobler; Martin F Fey
Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia.
Oncogene 1999;18(1):79-85.
1998: S Vonlanthen; Jim Heighway; Mario P Tschan; Markus M Borner; Hans J Altermatt; Andreas Kappeler; Andreas Tobler; Martin F Fey; N Thatcher; Wendell G Yarbrough; Daniel C Betticher
Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression.
Oncogene 1998;17(21):2779-85.
1998: Martin F Fey; Martin Blaser; Marion Wernli; Martine Jotterand; Rudolf Maibach; Alois Gratwohl; Andreas Tobler
Sampling bias and logistical problems of molecular analyses in a clinical leukaemia trial. Swiss Group for Clinical Cancer Research (SAKK)
British journal of haematology 1998;103(2):585-7.
1998: Daniel C Betticher; Daniel Ratschiller; Shu-Fang Hsu Schmitz; Albert Von Rohr; Urs Hess; Gilbert B Zulian; Marion Wernli; André Tichelli; Andreas Tobler; Martin F Fey; Thomas Cerny
Reduced dose of subcutaneous cladribine induces identical response rates but decreased toxicity in pretreated chronic lymphocytic leukaemia. Swiss Group for Clinical Cancer Research (SAKK).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1998;9(7):721-6.
1998: Markus M Borner; Monica Castiglione; M Bacchi; W Weber; Richard Herrmann; Martin F Fey; Olivia Pagani; Serge Leyvraz; Rudolf Morant; Bernhard C Pestalozzi; Silvia Hanselmann; Aron Goldhirsch
The impact of adding low-dose leucovorin to monthly 5-fluorouracil in advanced colorectal carcinoma: results of a phase III trial. Swiss Group for Clinical Cancer Research (SAKK).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1998;9(5):535-41.
1998: Daniel C Betticher; Albert Von Rohr; Daniel Ratschiller; Shu-Fang Hsu Schmitz; T Egger; T Sonderegger; Richard Herrmann; Th Kroner; Gilbert B Zulian; Franco Cavalli; Martin F Fey; Thomas Cerny
Fewer infections, but maintained antitumor activity with lower-dose versus standard-dose cladribine in pretreated low-grade non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(3):850-8.
1997: Martin F Fey
Microsatellite markers in leukaemia and lymphoma: comments on a timely topic.
Leukemia & lymphoma 1997;28(1-2):11-22.
1997: J Schwaller; Thomas Pabst; M Bickel; Bettina Borisch; Martin F Fey; Andreas Tobler
Comparative detection and quantitation of human CDK inhibitor mRNA expression of p15INK4B, p16INK4A, p16beta, p18INK4C, p19INK4D, p21WAF1, p27KIP1 and p57KIP2 by RT-PCR using a polycompetitive internal standard.
British journal of haematology 1997;99(4):896-900.
1997: Daniel C Betticher; Shu-Fang Hsu Schmitz; Daniel Ratschiller; Albert Von Rohr; T Egger; P Pugin; Mario Stalder; Urs Hess; Martin F Fey; Thomas Cerny
Cladribine (2-CDA) given as subcutaneous bolus injections is active in pretreated Waldenström's macroglobulinaemia. Swiss Group for Clinical Cancer Research (SAKK).
British journal of haematology 1997;99(2):358-63.
1997: Christoph Rochlitz; Andreas Lohri; G Sasse-Roth; B van Hille; J Reuter; André Tichelli; M Bacchi; Markus Fopp; Martin F Fey; Richard Herrmann
MTS1 expression and prognosis in acute myeloid leukemia.
Annals of hematology 1997;75(4):141-4.
1997: Andreas Lohri; B van Hille; M Bacchi; Markus Fopp; Franziska Joncourt; J Reuter; T Cerny; Martin F Fey; Richard Herrmann
Five putative drug resistance parameters (MDR1/P-glycoprotein, MDR-associated protein, glutathione-S-transferase, bcl-2 and topoisomerase IIalpha) in 57 newly diagnosed acute myeloid leukaemias. Swiss Group for Clinical Cancer Research (SAKK).
European journal of haematology 1997;59(4):206-15.
1997: Aron Goldhirsch; Richard D Gelber; Monica Castiglione; Anne O'Neill; Beat Thürlimann; Carl-Magnus Rudenstam; Jurij Lindtner; John Collins; J Forbes; Diana Crivellari; Alan Coates; Franco Cavalli; Edda Simoncini; Martin F Fey; Olivia Pagani; Karen Price; Hans-Jörg Senn
Menstrual cycle and timing of breast surgery in premenopausal node-positive breast cancer: results of the International Breast Cancer Study Group (IBCSG) Trial VI.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(8):751-6.
1997: Beat Thürlimann; Monica Castiglione; Shu-Fang Hsu Schmitz; Franco Cavalli; Hervé Bonnefoi; Martin F Fey; Rudolf Morant; T Löhnert; Aron Goldhirsch
Formestane versus megestrol acetate in postmenopausal breast cancer patients after failure of tamoxifen: a phase III prospective randomised cross over trial of second-line hormonal treatment (SAKK 20/90). Swiss Group for Clinical Cancer Research (SAKK)
European journal of cancer (Oxford, England : 1990) 1997;33(7):1017-24.
1997: P Kopp; Rolf Jaggi; A Tobler; B Borisch; M Oestreicher; L Sabacan; J Larry Jameson; Martin F Fey
Clonal X-inactivation analysis of human tumours using the human androgen receptor gene (HUMARA) polymorphism: a non-radioactive and semiquantitative strategy applicable to fresh and archival tissue.
Molecular and cellular probes 1997;11(3):217-28.
1997: Markus Fopp; Martin F Fey; M Bacchi; F Cavalli; J Gmuer; Emanuel Jacky; L Schmid; André Tichelli; Andreas Tobler; L Tschopp; V Von Fliedner; Alois Gratwohl
Post-remission therapy of adult acute myeloid leukaemia: one cycle of high-dose versus standard-dose cytarabine. Leukaemia Project Group of the Swiss Group for Clinical Cancer Research (SAKK).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(3):251-7.
1997: J Schwaller; UR Peters; Thomas Pabst; G Niklaus; D E Macfarlane; Martin F Fey; Andreas Tobler
Up-regulation of p21WAF1 expression in myeloid cells is activated by the protein kinase C pathway.
British journal of cancer 1997;76(12):1554-7.
1997: J Schwaller; Thomas Pabst; H P Koeffler; G Niklaus; Pius Loetscher; Martin F Fey; Andreas Tobler
Expression and regulation of G1 cell-cycle inhibitors (p16INK4A, p15INK4B, p18INK4C, p19INK4D) in human acute myeloid leukemia and normal myeloid cells.
Leukemia 1997;11(1):54-63.
1996: S Nagel; Bettina Borisch; A von Rohr; Andreas Tobler; Martin F Fey
Clonal analysis of a B-cell lymphoma with recurrent spontaneous remissions and evolution into chronic lymphocytic leukaemia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(9):953-60.
1996: Thomas Pabst; J Schwaller; Andreas Tobler; Martin F Fey
Detection of microsatellite markers in leukaemia using DNA from archival bone marrow smears.
British journal of haematology 1996;95(1):135-7.
1996: Thomas Pabst; J Schwaller; M J Bellomo; M Oestreicher; Dominique Mühlematter; André Tichelli; Andreas Tobler; Martin F Fey
Frequent clonal loss of heterozygosity but scarcity of microsatellite instability at chromosomal breakpoint cluster regions in adult leukemias.
Blood 1996;88(3):1026-34.
1996: Martin F Fey; Andreas Tobler
Tumour heterogeneity and clonality--an old theme revisited.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(2):121-8.
1995: S Nagel; Bettina Borisch; S L Thein; M Oestreicher; F Nöthiger; S Birrer; Andreas Tobler; Martin F Fey
Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intratumor heterogeneity in gastrointestinal cancers.
Cancer research 1995;55(13):2866-70.
1995: J Schwaller; Andreas Tobler; G Niklaus; N Hurwitz; I Hennig; Martin F Fey; Bettina Borisch
Interleukin-12 expression in human lymphomas and nonneoplastic lymphoid disorders.
Blood 1995;85(8):2182-8.
1995: J Schwaller; H P Koeffler; G Niklaus; Pius Loetscher; S Nagel; Martin F Fey; Andreas Tobler
Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells.
The Journal of clinical investigation 1995;95(3):973-9.
1995: Franziska Joncourt; A E Oberli-Schrämmli; M Stadler; K Buser; L Franscini; Martin F Fey; Thomas Cerny
Patterns of drug resistance parameters in adult leukemia.
Leukemia & lymphoma 1995;17(1-2):101-9.
1994: Peter Kopp; E T Kimura; S Aeschimann; M Oestreicher; Andreas Tobler; Martin F Fey; H Studer
Polyclonal and monoclonal thyroid nodules coexist within human multinodular goiters.
The Journal of clinical endocrinology and metabolism 1994;79(1):134-9.
1994: M Wernli; André Tichelli; V von Fliedner; G Brun del Re; B Chapuis; Martin F Fey; Markus Fopp; J Gmür; J P Grob; Emanuel Jacky
Intensive induction/consolidation therapy without maintenance in adult acute lymphoblastic leukaemia: a pilot assessment. Working Party on Leukaemia of the Swiss Group for Epidemiologic and Clinical Cancer Research (SAKK).
British journal of haematology 1994;87(1):39-43.
1994: T Chen; R Meier; Andrew Ziemiecki; Martin F Fey; Andreas Tobler
Myeloblastin/proteinase 3 belongs to the set of negatively regulated primary response genes expressed during in vitro myeloid differentiation.
Biochemical and biophysical research communications 1994;200(2):1130-5.
1994: Martin F Fey; S Liechti-Gallati; A von Rohr; Bettina Borisch; L Theilkäs; V Schneider; M Oestreicher; S Nagel; A Ziemiecki; Andreas Tobler
Clonality and X-inactivation patterns in hematopoietic cell populations detected by the highly informative M27 beta DNA probe.
Blood 1994;83(4):931-8.
1994: Daniel C Betticher; Martin F Fey; Albert Von Rohr; Andreas Tobler; H Jenzer; A Gratwohl; Andreas Lohri; P Pugin; Urs Hess; O Pagani
High incidence of infections after 2-chlorodeoxyadenosine (2-CDA) therapy in patients with malignant lymphomas and chronic and acute leukaemias.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5(1):57-64.
1993: Daniel C Betticher; Martin F Fey; M Rabaglio; Thomas Cerny; Urs Hess; V Meier; M Stalder; Gilbert B Zulian
Cladribine and severe myelotoxicity.
Lancet 1993;342(8883):1369.
1993: J Schwaller; T Chen; Martin F Fey; Andreas Tobler
A myeloblastin/proteinase-3 cDNA clone identifies a BglII and a PvuII restriction fragment length polymorphism.
Human genetics 1993;92(5):525.
1993: Andreas Tobler; Bernhard Moser; B Dewald; T Geiser; H Studer; Marco Baggiolini; Martin F Fey
Constitutive expression of interleukin-8 and its receptor in human myeloid and lymphoid leukemia.
Blood 1993;82(8):2517-25.
1993: G Favre; Markus Fopp; Jürg Gmür; André Tichelli; Martin F Fey; A Tobler; E Schatzmann; Alois Gratwohl
Factors associated with transfusion requirements during treatment for acute myelogenous leukemia.
Annals of hematology 1993;67(4):153-60.
1993: S Aeschimann; Peter Kopp; E T Kimura; J Zbaeren; Andreas Tobler; Martin F Fey; H Studer
Morphological and functional polymorphism within clonal thyroid nodules.
The Journal of clinical endocrinology and metabolism 1993;77(3):846-51.
1993: Franziska Joncourt; A Oberli; S M Redmond; Martin F Fey; Andreas Tobler; G P Margison; A Gratwohl; K Buser; Thomas Cerny
Cytostatic drug resistance: parallel assessment of glutathione-based detoxifying enzymes, O6-alkylguanine-DNA-alkyltransferase and P-glycoprotein in adult patients with leukaemia.
British journal of haematology 1993;85(1):103-11.
1993: Martin F Fey; Andreas Tobler
An interleukin-8 (IL-8) cDNA clone identifies a frequent HindIII polymorphism.
Human genetics 1993;91(3):298.
1993: Urs E Studer; Martin F Fey; A Calderoni; R Kraft; Luca Mazzucchelli; R W Sonntag
Adjuvant chemotherapy after orchiectomy in high-risk patients with clinical stage I non-seminomatous testicular cancer.
European urology 1993;23(4):444-9.
1992: Bettina Borisch; K C Gatter; Andreas Tobler; L Theilkäs; C Bunch; james wainscoat; Martin F Fey
Epstein-Barr virus-associated anaplastic large cell lymphoma in renal transplant patients.
American journal of clinical pathology 1992;98(3):312-8.
1992: Martin F Fey; Hans-Jakob Peter; H L Hinds; A Zimmermann; S Liechti-Gallati; Hans Gerber; H Studer; Andreas Tobler
Clonal analysis of human tumors with M27 beta, a highly informative polymorphic X chromosomal probe.
The Journal of clinical investigation 1992;89(5):1438-44.
1991: Martin F Fey; Andreas Tobler
Cancer diagnosis by molecular genetic probes: the present and the promise.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1991;2(9):629-33.
1991: Martin F Fey; Andreas Tobler
Assessment of DNA 'fingerprinting' as a method for validating the identity of cancer cell lines maintained in long-term culture.
Nucleic acids research 1991;19(12):3464.
1991: Andreas Tobler; H P Marti; C Gimmi; A B Cachelin; Susanne Saurer; Martin F Fey
Dexamethasone and 1,25-dihydroxyvitamin D3, but not cyclosporine A, inhibit production of granulocyte-macrophage colony-stimulating factor in human fibroblasts.
Blood 1991;77(9):1912-8.
1991: M Wernli; Alois Gratwohl; V von Fliedner; André Tichelli; F Clément; J P Grob; Bernard Chapuis; P Maurice; G Brun del Re; Martin F Fey
[The treatment of acute lymphatic leukemia in adults: pilot project with intensive early therapy without a maintenance phase].
Schweizerische medizinische Wochenschrift 1991;121(6):194-8.
1991: Martin F Fey; A E Kulozik; T E Hansen-Hagge; A Tobler
The polymerase chain reaction: a new tool for the detection of minimal residual disease in haematological malignancies.
European journal of cancer (Oxford, England : 1990) 1991;27(1):89-94.
1991: Bettina Borisch; Martin F Fey; Andreas Tobler; K Bürki; K C Gatter; james wainscoat
[Large cell anaplastic lymphomas in the immunocompromised host].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1991;75():171-4.
1990: Andreas Tobler; R Meier; L Theilkaes; A F Viollier; Martin F Fey
A myeloperoxidase cDNA clone identifies an EcoRV RFLP.
Nucleic acids research 1990;18(20):6176.
1990: Martin F Fey; Andreas Tobler; B Stadelmann; Andreas Hirt; L Theilkäs; E W Khandjian; Annette Ridolfi Lüthy; B Delaleu; R Weil; HP Wagner
Immunogenotyping with antigen receptor gene probes as a diagnostic tool in childhood acute lymphoblastic leukaemia.
European journal of haematology 1990;45(4):215-22.
1990: Martin F Fey; L Theilkäs; Andreas Tobler
Bone marrow trephine biopsies as a source of nucleic acids for molecular diagnosis of haematological neoplasms.
British journal of haematology 1990;74(2):229-31.