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Stanley Fields

Research Profile

Living Beings

Saccharomyces cerevisiae

Chemicals & Drugs

Procedures

Phenomena

Protein Binding

Physiology

Genes & Molecular Sequences

Anatomy

Kinetochores

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Publications

TOP 3
Lea M Starita; Russell S Lo; Jonathan N Pruneda; Jay Shendure; Peter S Brzovic; Stanley Fields; Douglas M Fowler; Joseph B Hiatt; Helen J Kim; Rachel E Klevit
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis.
Carlos L Araya; Wentao Chen; Douglas M Fowler; Jeffery W Kelly; Ike Muniez; Stanley Fields
A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function.
Anastasia McKinlay; Wayne Gerard; Stanley Fields
Global analysis of RNA oxidation in Saccharomyces cerevisiae.

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All Publications

2013: Lea M Starita; Russell S Lo; Jonathan N Pruneda; Jay Shendure; Peter S Brzovic; Stanley Fields; Douglas M Fowler; Joseph B Hiatt; Helen J Kim; Rachel E Klevit
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(14):E1263-72.
2012: Carlos L Araya; Wentao Chen; Douglas M Fowler; Jeffery W Kelly; Ike Muniez; Stanley Fields
A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(42):16858-63.
2012: Anastasia McKinlay; Wayne Gerard; Stanley Fields
Global analysis of RNA oxidation in Saccharomyces cerevisiae.
BioTechniques 2012;52(2):109-11.
2012: Lea M Starita; Priska D von Haller; Jimmy K Eng; Russell S Lo; Stanley Fields
Sites of ubiquitin attachment in Saccharomyces cerevisiae.
Proteomics 2012;12(2):236-40.
2011: Douglas M Fowler; Sara J Cooper; Jason J Stephany; Natalie Hendon; Sven Nelson; Stanley Fields
Suppression of statin effectiveness by copper and zinc in yeast and human cells.
Molecular bioSystems 2011;7(2):533-44.
2011: Liping Ren; Janel R McLean; Tony R Hazbun; Stanley Fields; Craig Vander Kooi; Melanie D Ohi; Kathleen L Gould
Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.
PloS one 2011;6(2):e16719.
2010: Kimberly Yasutis; Marissa Vignali; Matthew Ryder; Feven Tameire; Shubha A Dighe; Stanley Fields; Keith G Kozminski
Zds2p regulates Swe1p-dependent polarized cell growth in Saccharomyces cerevisiae via a novel Cdc55p interaction domain.
Molecular biology of the cell 2010;21(24):4373-86.
2010: Douglas M Fowler; Carlos L Araya; Sarel J Fleishman; Elizabeth H Kellogg; Jason J Stephany; David Baker; Stanley Fields
High-resolution mapping of protein sequence-function relationships.
Nature methods 2010;7(9):741-6.
2010: Sara J Cooper; Gregory L Finney; Shauna L Brown; Sven K Nelson; Jay R Hesselberth; Michael J MacCoss; Stanley Fields
High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection.
Genome research 2010;20(9):1288-96.
2010: Kevin Schutz; Jay R Hesselberth; Stanley Fields
Capture and sequence analysis of RNAs with terminal 2',3'-cyclic phosphates.
RNA (New York, N.Y.) 2010;16(3):621-31.
2010: Carlos L Araya; Celia Payen; Maitreya J Dunham; Stanley Fields
Whole-genome sequencing of a laboratory-evolved yeast strain.
BMC genomics 2010;11():88.
2009: Stanley Fields
Interactive learning: lessons from two hybrids over two decades.
Proteomics 2009;9(23):5209-13.
2009: Jay R Hesselberth; Xiaoyu Chen; Zhihong Zhang; Peter J Sabo; Richard Sandstrom; Alex P Reynolds; Robert E Thurman; Shane Neph; Michael S Kuehn; William S Noble; Stanley Fields; John A Stamatoyannopoulos
Global mapping of protein-DNA interactions in vivo by digital genomic footprinting.
Nature methods 2009;6(4):283-9.
2009: Douglas J LaCount; Lori W Schoenfeld; Stanley Fields
Selection of yeast strains with enhanced expression of Plasmodium falciparum proteins.
Molecular and biochemical parasitology 2009;163(2):119-22.
2008: Christopher L Brett; Rachael L Plemel; Braden T Lobinger; Marissa Vignali; Stanley Fields; Braden T Lobingier; Alexey J Merz
Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase.
The Journal of cell biology 2008;182(6):1141-51.
2008: Kristan K Steffen; Vivian L MacKay; Emily O Kerr; Mitsuhiro Tsuchiya; Di Hu; Lindsay A Fox; Nick Dang; Elijah D Johnston; Jonathan A Oakes; Bie N Tchao; Diana N Pak; Stanley Fields; Brian Kennedy; Matt Kaeberlein
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.
Cell 2008;133(2):292-302.
2008: Marissa Vignali; Anastasia McKinlay; Douglas J LaCount; Rakesh Chettier; Russell Bell; Sudhir Sahasrabudhe; Robert E Hughes; Stanley Fields
Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins.
Malaria journal 2008;7():211.
2007: Jonathan Wong; Yuko Nakajima; Stefan Westermann; Ching Shang; Jung-Seog Kang; Crystal Goodner; Pantea Houshmand; Stanley Fields; Clarence S M Chan; David G Drubin; Georjana Barnes; Tony R Hazbun
A protein interaction map of the mitotic spindle.
Molecular biology of the cell 2007;18(10):3800-9.
2007: Stanley Fields
Molecular biology. Site-seeing by sequencing.
Science (New York, N.Y.) 2007;316(5830):1441-2.
2007: Zhihong Zhang; Jay R Hesselberth; Stanley Fields
Genome-wide identification of spliced introns using a tiling microarray.
Genome research 2007;17(4):503-9.
2006: Tammi L Kaeberlein; Erica D Smith; Mitsuhiro Tsuchiya; K Linnea Welton; James H Thomas; Stanley Fields; Brian Kennedy; Matt Kaeberlein
Lifespan extension in Caenorhabditis elegans by complete removal of food.
Aging cell 2006;5(6):487-94.
2006: Ben Montpetit; Tony R Hazbun; Stanley Fields; Philip Hieter
Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation.
The Journal of cell biology 2006;174(5):653-63.
2006: Matt Kaeberlein; Kristan K Steffen; Di Hu; Nick Dang; Emily O Kerr; Mitsuhiro Tsuchiya; Stanley Fields; Brian Kennedy
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction".
Science (New York, N.Y.) 2006;312(5778):1312; author reply 1312.
2006: Fulai Jin; Tony R Hazbun; Gregory A Michaud; Michael Salcius; Paul Predki; Stanley Fields; Jing Huang
A pooling-deconvolution strategy for biological network elucidation.
Nature methods 2006;3(3):183-9.
2006: Victoria Brown; Rachel A Brown; Adrian Ozinsky; Jay R Hesselberth; Stanley Fields
Binding specificity of Toll-like receptor cytoplasmic domains.
European journal of immunology 2006;36(3):742-53.
2006: R Wilson Powers; Matt Kaeberlein; Seth D Caldwell; Brian Kennedy; Stanley Fields
Extension of chronological life span in yeast by decreased TOR pathway signaling.
Genes & development 2006;20(2):174-84.
2006: Jay R Hesselberth; John P Miller; Anna Golob; Jason E Stajich; Gregory A Michaud; Stanley Fields
Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins.
Genome biology 2006;7(4):R30.
2005: Matt Kaeberlein; R Wilson Powers; Kristan K Steffen; Eric A Westman; Di Hu; Nick Dang; Emily O Kerr; Kathryn T Kirkland; Stanley Fields; Brian Kennedy
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.
Science (New York, N.Y.) 2005;310(5751):1193-6.
2005: Douglas J LaCount; Marissa Vignali; Rakesh Chettier; Amit R Phansalkar; Russell Bell; Jay R Hesselberth; Lori W Schoenfeld; Irene Ota; Sudhir Sahasrabudhe; Cornelia Kurschner; Stanley Fields; Robert E Hughes
A protein interaction network of the malaria parasite Plasmodium falciparum.
Nature 2005;438(7064):103-7.
2005: Matt Kaeberlein; Di Hu; Emily O Kerr; Mitsuhiro Tsuchiya; Eric A Westman; Nick Dang; Stanley Fields; Brian Kennedy
Increased life span due to calorie restriction in respiratory-deficient yeast.
PLoS genetics 2005;1(5):e69.
2005: Stanley Fields
High-throughput two-hybrid analysis. The promise and the peril.
The FEBS journal 2005;272(21):5391-9.
2005: Anne-Claude Gingras; Michael Caballero; Marcel Zarske; Amy Sanchez; Tony R Hazbun; Stanley Fields; Nahum Sonenberg; Ernst Hafen; Brian Raught; Ruedi Aebersold
A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.
Molecular & cellular proteomics : MCP 2005;4(11):1725-40.
2005: John P Miller; Russell S Lo; Asa Ben-Hur; Cynthia Desmarais; Igor Stagljar; William Stafford Noble; Stanley Fields
Large-scale identification of yeast integral membrane protein interactions.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(34):12123-8.
2005: Matt Kaeberlein; Thomas McDonagh; Birgit Heltweg; Jeffrey Hixon; Eric A Westman; Seth D Caldwell; Andrew D Napper; Rory Curtis; Peter S DiStefano; Stanley Fields; Antonio Bedalov; Brian Kennedy
Substrate-specific activation of sirtuins by resveratrol.
The Journal of biological chemistry 2005;280(17):17038-45.
2005: Michael Devit; Paul J Cullen; Margaret Branson; George F Sprague; Stanley Fields
Forcing interactions as a genetic screen to identify proteins that exert a defined activity.
Genome research 2005;15(4):560-5.
2005: Matt Kaeberlein; Kathryn T Kirkland; Stanley Fields; Brian Kennedy
Genes determining yeast replicative life span in a long-lived genetic background.
Mechanisms of ageing and development 2005;126(4):491-504.
2005: Stanley Fields; Mark Johnston
Cell biology. Whither model organism research?
Science (New York, N.Y.) 2005;307(5717):1885-6.
2004: Lisa M Antoniacci; Margaret A Kenna; Peter Uetz; Stanley Fields; Robert V Skibbens
The spindle pole body assembly component mps3p/nep98p functions in sister chromatid cohesion.
The Journal of biological chemistry 2004;279(47):49542-50.
2004: Matt Kaeberlein; Kathryn T Kirkland; Stanley Fields; Brian Kennedy
Sir2-independent life span extension by calorie restriction in yeast.
PLoS biology 2004;2(9):E296.
2004: Andrei Alexandrov; Marissa Vignali; Douglas J LaCount; Erin Quartley; Christina de Vries; Daniela De Rosa; Julie Babulski; Sarah F Mitchell; Lori W Schoenfeld; Stanley Fields; Wim G Hol; Mark E Dumont; Eric M Phizicky; Elizabeth J Grayhack
A facile method for high-throughput co-expression of protein pairs.
Molecular & cellular proteomics : MCP 2004;3(9):934-8.
2004: Dawei Guo; Tony R Hazbun; Xin-Jing Xu; Sze-Ling Ng; Stanley Fields; Min-Hao Kuo
A tethered catalysis, two-hybrid system to identify protein-protein interactions requiring post-translational modifications.
Nature biotechnology 2004;22(7):888-92.
2003: Tony R Hazbun; Lars Malmström; Scott Anderson; Beth J Graczyk; Bethany Fox; Michael Riffle; Bryan A Sundin; J Derringer Aranda; W Hayes McDonald; Chun-Hwei Chiu; Brian E Snydsman; Philip Bradley; Eric G D Muller; Stanley Fields; David Baker; John R Yates; Trisha Davis
Assigning function to yeast proteins by integration of technologies.
Molecular cell 2003;12(6):1353-65.
2003: Ming Guo; Christopher Aston; Scott A Burchett; Christine Dyke; Stanley Fields; S Johannes R Rajarao; Peter Uetz; Yuqi Wang; Kathleen Young; Henrik G Dohlman
The yeast G protein alpha subunit Gpa1 transmits a signal through an RNA binding effector protein Scp160.
Molecular cell 2003;12(2):517-24.
2003: Ching Shang; Tony R Hazbun; Iain M Cheeseman; Jennifer Aranda; Stanley Fields; David G Drubin; Georjana Barnes
Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p.
Molecular biology of the cell 2003;14(8):3342-55.
2003: Katsumi Kitagawa; Rashid Abdulle; Parmil K Bansal; Gerard Cagney; Stanley Fields; Philip Hieter
Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint.
Molecular cell 2003;11(5):1201-13.
2003: Isabelle Pot; Vivien Measday; Brian E Snydsman; Gerard Cagney; Stanley Fields; Trisha Davis; Eric G D Muller; Philip Hieter
Chl4p and iml3p are two new members of the budding yeast outer kinetochore.
Molecular biology of the cell 2003;14(2):460-76.
2002: Tony R Hazbun; Stanley Fields
A genome-wide screen for site-specific DNA-binding proteins.
Molecular & cellular proteomics : MCP 2002;1(7):538-43.
2002: Scott A Burchett; Paul Flanary; Christopher Aston; Lixin Jiang; Kathleen H Young; Peter Uetz; Stanley Fields; Henrik G Dohlman
Regulation of stress response signaling by the N-terminal dishevelled/EGL-10/pleckstrin domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae.
The Journal of biological chemistry 2002;277(25):22156-67.
2002: Stanley Fields; Mark Johnston
Genomics. A crisis in postgenomic nomenclature.
Science (New York, N.Y.) 2002;296(5568):671-2.
2002: Paul J Muchowski; Ke Ning; Crislyn D'Souza-Schorey; Stanley Fields
Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):727-32.
2002: Amy Hin Yan Tong; Becky Drees; Giuliano Nardelli; Gary Bader; Barbara Brannetti; Luisa Castagnoli; Marie Evangelista; Silvia Ferracuti; Bryce Nelson; Serena Paoluzi; Michele Quondam; Adriana Zucconi; Christopher W V Hogue; Stanley Fields; Charles Boone; Gianni Cesareni
A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules.
Science (New York, N.Y.) 2002;295(5553):321-4.
2002: Eric M Phizicky; Mark R Martzen; Stephen M McCraith; Sherry L Spinelli; Feng Xing; Neil P Shull; Ceri Van Slyke; Rebecca K Montagne; Francy M Torres; Stanley Fields; Elizabeth J Grayhack
Biochemical genomics approach to map activities to genes.
Methods in enzymology 2002;350():546-59.
2002: Joseph F Gera; Tony R Hazbun; Stanley Fields
Array-based methods for identifying protein-protein and protein-nucleic acid interactions.
Methods in enzymology 2002;350():499-512.
2002: Vivien Measday; Dale W Hailey; Isabelle Pot; Scott A Givan; Katherine M Hyland; Gerard Cagney; Stanley Fields; Trisha Davis; Philip Hieter
Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.
Genes & development 2002;16(1):101-13.
2001: Robert E Hughes; R S Lo; C Davis; A D Strand; CL Neal; J M Olson; Stanley Fields
Altered transcription in yeast expressing expanded polyglutamine.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13201-6.
2001: Chandra L Tucker; Stanley Fields
A yeast sensor of ligand binding.
Nature biotechnology 2001;19(11):1042-6.
2001: Stanley Fields
The interplay of biology and technology.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10051-4.
2001: Becky Drees; Bryan A Sundin; E Brazeau; Juliane P Caviston; GC Chen; Wei Guo; Keith G Kozminski; M W Lau; J J Moskow; A Tong; Laura R Schenkman; A McKenzie; Patrick Brennwald; Mark S Longtine; Erfei Bi; C Chan; Peter Novick; Charles Boone; John R Pringle; Trisha Davis; Stanley Fields; David G Drubin
A protein interaction map for cell polarity development.
The Journal of cell biology 2001;154(3):549-71.
2001: Tony R Hazbun; Stanley Fields
Networking proteins in yeast.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4277-8.
2001: Stanley Fields
Proteomics. Proteomics in genomeland.
Science (New York, N.Y.) 2001;291(5507):1221-4.
2001: Stanley Fields; P L Bartel
The two-hybrid system. A personal view.
Methods in molecular biology (Clifton, N.J.) 2001;177():3-8.
2000: S McCraith; T Holtzman; Bernard Moss; Stanley Fields
Genome-wide analysis of vaccinia virus protein-protein interactions.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4879-84.
2000: Peter Uetz; L Giot; Gerard Cagney; T A Mansfield; R S Judson; J R Knight; Daniel Lockshon; V Narayan; M Srinivasan; P Pochart; A Qureshi-Emili; Y Li; B Godwin; D Conover; Theodore Kalbfleisch; G Vijayadamodar; M Yang; M Johnston; Stanley Fields; Jonathan M Rothberg
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae.
Nature 2000;403(6770):623-7.
2000: Gerard Cagney; Peter Uetz; Stanley Fields
High-throughput screening for protein-protein interactions using two-hybrid assay.
Methods in enzymology 2000;328():3-14.
1999: Mark R Martzen; Stephen M McCraith; Sherry L Spinelli; F M Torres; Stanley Fields; Elizabeth J Grayhack; Eric M Phizicky
A biochemical genomics approach for identifying genes by the activity of their products.
Science (New York, N.Y.) 1999;286(5442):1153-5.
1999: Stanley Fields; Y Kohara; David J Lockhart
Functional genomics.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):8825-6.
1997: J R Hudson; E P Dawson; K L Rushing; C H Jackson; Daniel Lockshon; D Conover; C Lanciault; J R Harris; S J Simmons; R Rothstein; Stanley Fields
The complete set of predicted genes from Saccharomyces cerevisiae in a readily usable form.
Genome research 1997;7(12):1169-73.