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Martin Filipec

Research Profile

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Czech Republic

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Petra Liskova; Alex G Morris; Stanislava Reinstein Merjava; Tom R Webb; Shomi S Bhattacharya; Panos Deloukas; Neil ebenezer; Martin Filipec; Rhian Gwilliam; Katerina Jirsova; Alison J Hardcastle
High prevalence of posterior polymorphous corneal dystrophy in the Czech Republic; linkage disequilibrium mapping and dating an ancestral mutation.
Stanislava Merjava; Kyra Michalova; Zuzana Zemanova; Martin Filipec; Petra Liskova; Eva Malinova; Katerina Jirsova
Recurrence of posterior polymorphous corneal dystrophy is caused by the overgrowth of the original diseased host endothelium.
Anna Lenčová; Kateřina Pokorná; Alena Zajícová; Magdaléna Krulová; Martin Filipec; Vladimír Holáň
Graft survival and cytokine production profile after limbal transplantation in the experimental mouse model.

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All Publications

2012: Petra Liskova; Alex G Morris; Stanislava Reinstein Merjava; Tom R Webb; Shomi S Bhattacharya; Panos Deloukas; Neil ebenezer; Martin Filipec; Rhian Gwilliam; Katerina Jirsova; Alison J Hardcastle
High prevalence of posterior polymorphous corneal dystrophy in the Czech Republic; linkage disequilibrium mapping and dating an ancestral mutation.
PloS one 2012;7(9):e45495.
2011: Stanislava Merjava; Kyra Michalova; Zuzana Zemanova; Martin Filipec; Petra Liskova; Eva Malinova; Katerina Jirsova
Recurrence of posterior polymorphous corneal dystrophy is caused by the overgrowth of the original diseased host endothelium.
Histochemistry and cell biology 2011;136(1):93-101.
2011: Anna Lenčová; Kateřina Pokorná; Alena Zajícová; Magdaléna Krulová; Martin Filipec; Vladimír Holáň
Graft survival and cytokine production profile after limbal transplantation in the experimental mouse model.
Transplant immunology 2011;24(3):189-94.
2010: Petra Liskova; Martin Filipec; Stanislava Merjava; Katerina Jirsova; Stephen J Tuft
Variable ocular phenotypes of posterior polymorphous corneal dystrophy caused by mutations in the ZEB1 gene.
Ophthalmic genetics 2010;31(4):230-4.
2009: Jitka Cejková; Taras Ardan; Cestmír Cejka; J Malec; K Jirsová; Martin Filipec; E Ruzicková; D Dotrelová; Blanka Brunová
Ocular surface injuries in autoimmune dry eye. The severity of microscopical disturbances goes parallel with the severity of symptoms of dryness.
Histology and histopathology 2009;24(10):1357-65.
2009: Kristyna Brejchova; Petra Liskova; Enkela Hrdlickova; Martin Filipec; Katerina Jirsova
Matrix metalloproteinases in recurrent corneal melting associated with primary Sjörgen's syndrome.
Molecular vision 2009;15():2364-72.
2008: Magdalena Krulova; Katerina Pokorna; Anna Lencova; Fric Jan; Alena Zajicova; Martin Filipec; John V Forrester; Vladimir Holan
A rapid separation of two distinct populations of mouse corneal epithelial cells with limbal stem cell characteristics by centrifugation on percoll gradient.
Investigative ophthalmology & visual science 2008;49(9):3903-8.
2008: Petra Liskova; B Veraitch; Katerina Jirsova; Martin Filipec; A Neuwirth; Neil D Ebenezer; Pirro G Hysi; Alison J Hardcastle; Stephen J Tuft; Shomi S Bhattacharya
Sequencing of the CHST6 gene in Czech macular corneal dystrophy patients supports the evidence of a founder mutation.
The British journal of ophthalmology 2008;92(2):265-7.
2008: Petra Liskova; Gordon K Klintworth; Brandy L Bowling; Martin Filipec; Katerina Jirsova; Stephen J Tuft; Shomi S Bhattacharya; Alison J Hardcastle; Neil D Ebenezer
Phenotype associated with the H626P mutation and other changes in the TGFBI gene in Czech families.
Ophthalmic research 2008;40(2):105-8.
2007: Klara Sedlakova; Martin Filipec
Effect of suturing technique on corneal xenograft survival.
Cornea 2007;26(9):1111-4.
2007: Katerina Jirsova; Kristyna Juklova; Aref Alfakih; Martin Filipec
Presence of snake-like chromatin in epithelial cells of keratoconjunctivitis sicca followed by a large number of micronuclei.
Acta cytologica 2007;51(4):541-6.
2007: Petra Liskova; Stephen J Tuft; Rhian Gwilliam; Neil D Ebenezer; Katerina Jirsova; Quincy Prescott; Martincova Radka; Marike Pretorius; Neil Sinclair; David L Boase; Margaret J Jeffrey; Panos Deloukas; Alison J Hardcastle; Martin Filipec; Shomi S Bhattacharya
Novel mutations in the ZEB1 gene identified in Czech and British patients with posterior polymorphous corneal dystrophy.
Human mutation 2007;28(6):638.
2007: Urania Tavandzi; Radek Procházka; Dusan Usvald; Jana Hlucílová; Martina Vitásková; Jan Motlík; Andrea Vítová; Martin Filipec; John V Forrester; Vladimír Holán
A new model of corneal transplantation in the miniature pig: efficacy of immunosuppressive treatment.
Transplantation 2007;83(10):1401-3.
2007: Katerina Jirsova; Stanislava Merjava; Martincova Radka; Rhian Gwilliam; Neil D Ebenezer; Petra Liskova; Martin Filipec
Immunohistochemical characterization of cytokeratins in the abnormal corneal endothelium of posterior polymorphous corneal dystrophy patients.
Experimental eye research 2007;84(4):680-6.
2007: Robert Dobrovolny; Petra Liskova; Jana Ledvinova; Helena Poupetova; Befekadu Asfaw; Martin Filipec; Katerina Jirsova; Josef Kraus; Milan Elleder
Mucolipidosis IV: report of a case with ocular restricted phenotype caused by leaky splice mutation.
American journal of ophthalmology 2007;143(4):663-71.
2006: Katerina Jirsova; K Juklova; V Vesela; Martin Filipec
Morphological and immunocytochemical characterization of snake-like chromatin cells.
Histology and histopathology 2006;21(4):355-60.
2005: Rhian Gwilliam; Petra Liskova; Martin Filipec; Stanislav Kmoch; Katerina Jirsova; Elizabeth J Huckle; Catherine L Stables; Shomi S Bhattacharya; Alison J Hardcastle; Panos Deloukas; Neil D Ebenezer
Posterior polymorphous corneal dystrophy in Czech families maps to chromosome 20 and excludes the VSX1 gene.
Investigative ophthalmology & visual science 2005;46(12):4480-4.
2005: Vladimír Holán; Andrea Vítová; Magdaléna Krulová; Alena Zajícová; Ales Neuwirth; Martin Filipec; John V Forrester
Susceptibility of corneal allografts and xenografts to antibody-mediated rejection.
Immunology letters 2005;100(2):211-3.
2005: Jana Pindjáková; Andrea Vítová; Magdaléna Krulová; Alena Zajícová; Martin Filipec; Vladimír Holán
Corneal rat-to-mouse xenotransplantation and the effects of anti-CD4 or anti-CD8 treatment on cytokine and nitric oxide production.
Transplant international : official journal of the European Society for Organ Transplantation 2005;18(7):854-62.
2005: Klára Sedláková; Elizabeth Muckersie; Marie Robertson; Martin Filipec; John V Forrester
FTY720 in corneal concordant xenotransplantation.
Transplantation 2005;79(3):297-303.
2004: Andrea Vítová; Martin Filipec; Alena Zajícová; Magdaléna Krulová; Vladimír Holán
Prevention of corneal allograft rejection in a mouse model of high risk recipients.
The British journal of ophthalmology 2004;88(10):1338-42.
2004: Jarka Heissigerova; L Kuffova; Martin Filipec; V Holan; John V Forrester
Quantitative evaluation of the corneal endothelium in the mouse after grafting.
The British journal of ophthalmology 2004;88(9):1209-16.
2004: Vladimír Holán; Andrea Vítová; Jana Pindjáková; Magdaléna Krulová; Alena Zajícová; Martin Filipec
Corneal stromal cells selectively inhibit production of anti-inflammatory cytokines by activated T cells.
Clinical and experimental immunology 2004;136(2):200-6.
2004: Jarmila Plsková; Vladimír Holán; Martin Filipec; John V Forrester
Lymph node removal enhances corneal graft survival in mice at high risk of rejection.
BMC ophthalmology 2004;4():3.
2003: Petra Strestíková; Jarmila Plsková; Martin Filipec; Hassan Farghali
FK 506 and aminoguanidine suppress iNOS induction in orthotopic corneal allografts and prolong graft survival in mice.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003;9(2):111-7.
2002: Jarmila Plsková; Linda Duncan; Vladimír Holán; Martin Filipec; Georg Kraal; John V Forrester
The immune response to corneal allograft requires a site-specific draining lymph node.
Transplantation 2002;73(2):210-5.
2002: Jarmila Plsková; Lucia Kuffová; Vladimír Holán; Martin Filipec; John V Forrester
Evaluation of corneal graft rejection in a mouse model.
The British journal of ophthalmology 2002;86(1):108-13.
2001: Enkela Hrdlicková-Cela; Jan Plzák; Karel Smetana; Z Mĕlková; Herbert Kaltner; Martin Filipec; Fu-Tong Liu; Hans-Joachim Gabius
Detection of galectin-3 in tear fluid at disease states and immunohistochemical and lectin histochemical analysis in human corneal and conjunctival epithelium.
The British journal of ophthalmology 2001;85(11):1336-40.
2001: Lucia Kuffová; L Lumsden; V Veselá; J A Taylor; Martin Filipec; Vladimír Holán; Andrew D Dick; John V Forrester
Kinetics of leukocyte and myeloid cell traffic in the murine corneal allograft response.
Transplantation 2001;72(7):1292-8.
2001: Petra Strestíková; Berta Otová; Martin Filipec; Karel Masek; Hassan Farghali
Different mechanisms in inhibition of rat macrophage nitric oxide synthase expression by FK 506 and cyclosporin A.
Immunopharmacology and immunotoxicology 2001;23(1):67-74.
2000: Vladimír Holán; Alena Zajícová; Magdaléna Krulová; Jarmila Plsková; Fric Jan; Martin Filipec
Induction of specific transplantation immunity by oral immunization with allogeneic cells.
Immunology 2000;101(3):404-11.
2000: Stanislav Kmoch; Jirí Brynda; Befekadu Asfaw; Karel Bezouska; Petr Novák; Pavlína Rezácová; L Ondrová; Martin Filipec; Juraj Sedlácek; Milan Elleder
Link between a novel human gammaD-crystallin allele and a unique cataract phenotype explained by protein crystallography.
Human molecular genetics 2000;9(12):1779-86.
2000: Petra Strestíková; Berta Otová; Martin Filipec; Hassan Farghali
Inhibitory effect of FK 506 and cyclosporin A on nitric oxide production by LPS-treated cultured rat macrophages.
Physiological research / Academia Scientiarum Bohemoslovaca 2000;49(6):725-8.
1999: Lucia Kuffová; Vladimír Holán; L Lumsden; John V Forrester; Martin Filipec
Cell subpopulations in failed human corneal grafts.
The British journal of ophthalmology 1999;83(12):1364-9.
1999: Andrew W Lloyd; S Dropcova; Richard G A Faragher; Paul R Gard; Geoffrey W Hanlon; Sergey V Mikhalovsky; CJ Olliff; Stephen P Denyer; E Letko; Martin Filipec
The development of in vitro biocompatibility tests for the evaluation of intraocular biomaterials.
Journal of materials science. Materials in medicine 1999;10(10/11):621-7.
1999: Magdaléna Krulová; Lucia Kuffová; Alena Zajícová; Martin Filipec; Vladimír Holán
IL-10 is an effector molecule mediating urocanic acid-induced immunosuppression.
Transplantation proceedings 1999;31(1-2):1218-9.
1999: Zdenka Haskova; Martin Filipec; Vladimír Holán
Enhanced IL-10 and decreased IL-2 production after orthotopic corneal transplantation in mice.
Folia biologica 1999;45(1):21-5.
1998: Vladimír Holán; Lucia Kuffová; Alena Zajícová; Magdaléna Krulová; Martin Filipec; P Holler; A Jancárek
Urocanic acid enhances IL-10 production in activated CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3237-41.
1998: Martin Filipec; E Letko; Zdenka Haskova; D Jenícková; P Holler; A Jancárek; Vladimír Holán
The effect of urocanic acid on graft rejection in an experimental model of orthotopic corneal transplantation in rabbits.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(1):65-8.
1997: Zdenka Haskova; Martin Filipec; Vladimír Holán
[The significance of gender incompatibility in donors and recipients and the role of minor histocompatibility antigens in corneal transplantation].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 1997;53(2):128-35.
1997: Ivan Karel; Bohdana Kalvodová; Martin Filipec; E Bohácová; Pavel Soucek; Ctibor Povýsil; Jirí Vacík; M Tlustáková
Poly (triethylenglycol monomethacrylate) and poly (glycerol monomethacrylate) cross-linked gel as potential viscoelastics for intraoperative use.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(3):186-9.
1996: J Hycl; Martin Filipec
[Phacoemulsification in high myopia].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 1996;52 Suppl():20-5.
1996: P Diblík; H Kraus; Martin Filipec; J Hycl; L Splíchal
[Ambulatory cataract surgery].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 1996;52 Suppl():17-9.
1996: Vladimír Holán; Zdenka Haskova; Martin Filipec
Transplantation immunity and tolerance in the eye: rejection and acceptance of orthotopic corneal allografts in mice.
Transplantation 1996;62(8):1050-4.
1996: Zdenka Haskova; Martin Filipec; E Letko; Vladimír Holán
[Experimental models of corneal transplantation].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 1996;52(4):263-9.
1996: Martin Filipec; Zdenka Haskova; K Havrlíková; E Letko; Vladimír Holán; Jaroslav Matousek; I Kalousek
Immunosuppressive effect of bovine seminal ribonuclease on a model of corneal transplantation in rabbit.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234(9):586-90.
1996: Zdenka Haskova; Martin Filipec; Vladimír Holán
The role of major and minor histocompatibility antigens in orthotopic corneal transplantation in mice.
Folia biologica 1996;42(3):105-11.
1994: Martin Filipec; J Hycl; H Kraus
[Does vascularization and the graft diameter affect the rejection reaction in corneal transplantation?].
Ceskoslovenská oftalmologie 1994;50(1):13-7.
1993: Martin Filipec; Ivan Karel; M Michalicková
[Malignant intraocular lymphoma].
Ceskoslovenská oftalmologie 1993;49(2):72-5.
1990: H Kraus; Martin Filipec
[Surgery in sequelae of chemical and thermal burns of the eye].
Ceskoslovenská oftalmologie 1990;46(5):341-8.
1989: Martin Filipec; Ivan Karel; W Pedal; Pavel Haninec
Specular and scanning electron microscopy in diffuse silicone keratopathy.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1989;227(5):417-20.
1987: Martin Filipec; H Kraus
[Specular microscopy in the endothelium rejection reaction after corneal transplant].
Ceskoslovenská oftalmologie 1987;43(5):310-5.
1986: S Pitrová; E Růzicková; H Kraus; A Ciháková; Martin Filipec
[Diagnosis and present possibilities of treatment of pseudoexfoliative glaucoma].
Ceskoslovenská oftalmologie 1986;42(1):13-20.
1986: Ivan Karel; Martin Filipec; J Obenberger
Specular microscopy of the corneal endothelium after liquid silicone injection into the vitreous in complicated retinal detachments.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1986;224(2):195-200.
1986: Ivan Karel; Martin Filipec; F Vrabec; J Obenberger
The effect of liquid silicone on the corneal endothelium in rabbits. A comparative specular microscopic and histopathologic study.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1986;224(5):481-5.
1982: H Kraus; E Růzicková; S Pitrová; Martin Filipec
[Keratoplasty in eyes after chemical and thermal burns].
Ceskoslovenská oftalmologie 1982;38(6):384-9.