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Aleksandra Filipovska

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Judith M Myers; William E Antholine; Elias S J Arnér; Qing Cheng; Aleksandra Filipovska; Balaraman Kalyanaraman; Charles R Myers
Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping.
Aleksandra Filipovska; Oliver Rackham
Specialization from synthesis: how ribosome diversity can customize protein function.
Helena M Viola; Stefan M K Davies; Aleksandra Filipovska; Livia C Hool
L-type Ca(2+) channel contributes to alterations in mitochondrial calcium handling in the mdx ventricular myocyte.

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All Publications

2013: Judith M Myers; William E Antholine; Elias S J Arnér; Qing Cheng; Aleksandra Filipovska; Balaraman Kalyanaraman; Charles R Myers
Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trapping.
Free radical biology & medicine 2013;60():183-94.
2013: Aleksandra Filipovska; Oliver Rackham
Specialization from synthesis: how ribosome diversity can customize protein function.
FEBS letters 2013;587(8):1189-97.
2013: Helena M Viola; Stefan M K Davies; Aleksandra Filipovska; Livia C Hool
L-type Ca(2+) channel contributes to alterations in mitochondrial calcium handling in the mdx ventricular myocyte.
American journal of physiology. Heart and circulatory physiology 2013;304(6):H767-75.
2013: Ross Thyer; Aleksandra Filipovska; Oliver Rackham
Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation.
Journal of the American Chemical Society 2013;135(1):2-5.
2012: Assen Jablensky; S MacGregor; A McRae; Bharti Morar; D W Morris; M Phillips; Oliver Rackham; Kim Rasmussen; A Usheva; P L Verbrugghe; C S Weickert; Boian Alexandrov; Osvaldo P Almeida; Dora Angelicheva; D N Azmanov; Johanna Badcock; A R Bishop; E Bramon-Bosch; Kim Carter; David Chandler; M Cooper; Aiden Corvin; Mark Nicholas Cruickshank; Gary Donohoe; Milan Dragovic; Aleksandra Filipovska; Leon Flicker; M Gill; Luba Kalaydjieva
Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia.
Molecular psychiatry 2012;17(12):1328-39.
2012: Stefan M K Davies; Maria I G Lopez Sanchez; Reena Narsai; Oliver Rackham; Muhammad F M Razif; Anne-Marie J Shearwood; Ian D Small; James Whelan; Aleksandra Filipovska
MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins.
FEBS letters 2012;586(20):3555-61.
2012: Oliver Rackham; Timothy R Mercer; Aleksandra Filipovska
The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression.
Wiley interdisciplinary reviews. RNA 2012;3(5):675-95.
2012: Oliver Rackham; Aleksandra Filipovska
The role of mammalian PPR domain proteins in the regulation of mitochondrial gene expression.
Biochimica et biophysica acta 2012;1819(9-10):1008-16.
2012: Daniel M Passon; Oliver Rackham; Agata Sadowska; Will A Stanley; Aleksandra Filipovska; Archa Fox; Mihwa Lee; Charles Bond
Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(13):4846-50.
2012: Aleksandra Filipovska; Oliver Rackham
Modular recognition of nucleic acids by PUF, TALE and PPR proteins.
Molecular bioSystems 2012;8(3):699-708.
2011: Oliver Rackham; Anne-Marie J Shearwood; Stefan M K Davies; John S Mattick; Tim R Mercer; Aleksandra Filipovska
Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins.
RNA (New York, N.Y.) 2011;17(12):2085-93.
2011: Aleksandra Filipovska; Oliver Rackham
Designer RNA-binding proteins: New tools for manipulating the transcriptome.
RNA biology 2011;8(6):978-83.
2011: Helen Tang; Helena M Viola; Aleksandra Filipovska; Livia C Hool
Ca(v)1.2 calcium channel is glutathionylated during oxidative stress in guinea pig and ischemic human heart.
Free radical biology & medicine 2011;51(8):1501-11.
2011: Maria I G Lopez Sanchez; Stefan M K Davies; John S Mattick; Tim R Mercer; Karoline K A Nygård; Oliver Rackham; Tara R Richman; Anne-Marie J Shearwood; Aleksandra Filipovska
RNA processing in human mitochondria.
Cell cycle (Georgetown, Tex.) 2011;10(17):2904-16.
2011: Susan J Berners-Price; Aleksandra Filipovska
Gold compounds as therapeutic agents for human diseases.
Metallomics : integrated biometal science 2011;3(9):863-73.
2011: Tim R Mercer; Shane Neph; Oliver Rackham; Anne-Marie J Shearwood; Martin A Smith; John A Stamatoyannopoulos; Cameron P Bracken; Joanna Crawford; Marcel Dinger; Aleksandra Filipovska; Eric Haugen; John S Mattick
The human mitochondrial transcriptome.
Cell 2011;146(4):645-58.
2011: Aleksandra Filipovska; Karoline K A Nygård; Muhammad F M Razif; Oliver Rackham
A universal code for RNA recognition by PUF proteins.
Nature chemical biology 2011;7(7):425-7.
2011: Oliver Rackham; Anne-Marie J Shearwood; Ross Thyer; Elyshia McNamara; Stefan M K Davies; Bernard A Callus; Antonio Miranda-Vizuete; Susan J Berners-Price; Qing Cheng; Elias Arnér; Aleksandra Filipovska
Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.
Free radical biology & medicine 2011;50(6):689-99.
2010: Chris Carrie; Estelle Giraud; Owen Duncan; Lin Xu; Yan Wang; Shaobai Huang; Rachel Clifton; Monika Murcha; Aleksandra Filipovska; Oliver Rackham; Alice Vrielink; James Whelan
Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomes.
The Journal of biological chemistry 2010;285(46):36138-48.
2009: Richard J Bowen; Maribel Navarro; Anne-Marie J Shearwood; Peter C Healy; Brian W Skelton; Aleksandra Filipovska; Susan J Berners-Price
1 : 2 Adducts of copper(I) halides with 1,2-bis(di-2-pyridylphosphino)ethane: solid state and solution structural studies and antitumour activity.
Dalton transactions (Cambridge, England : 2003) 2009;(48):10861-70.
2009: Oliver Rackham; Stefan M K Davies; Anne-Marie J Shearwood; Kristina L Hamilton; James Whelan; Aleksandra Filipovska
Pentatricopeptide repeat domain protein 1 lowers the levels of mitochondrial leucine tRNAs in cells.
Nucleic acids research 2009;37(17):5859-67.
2009: Stefan M K Davies; Oliver Rackham; Anne-Marie J Shearwood; Kristina L Hamilton; Reena Narsai; James Whelan; Aleksandra Filipovska
Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation.
FEBS letters 2009;583(12):1853-8.
2009: Kristen J Nowak; Gianina Ravenscroft; Connie Jackaman; Aleksandra Filipovska; Stefan M Davies; Esther M Lim; Sarah E Squire; Allyson C Potter; Elizabeth Baker; Sophie Clément; Caroline A Sewry; Victoria Fabian; Kelly Crawford; James L Lessard; Lisa M Griffiths; John M Papadimitriou; Yun Shen; Grant Morahan; Anthony J Bakker; Kay E Davies; Nigel G Laing
Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.
The Journal of cell biology 2009;185(5):903-15.
2008: James L Hickey; Rasha A Ruhayel; Peter Barnard; Murray V Baker; Susan J Berners-Price; Aleksandra Filipovska
Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols.
Journal of the American Chemical Society 2008;130(38):12570-1.
2008: Thomas R Hurd; Raquel Requejo; Aleksandra Filipovska; Stephanie Brown; Tracy A Prime; Alan J Robinson; Ian M Fearnley; Michael P Murphy
Complex I within oxidatively stressed bovine heart mitochondria is glutathionylated on Cys-531 and Cys-704 of the 75-kDa subunit: potential role of CYS residues in decreasing oxidative damage.
The Journal of biological chemistry 2008;283(36):24801-15.
2008: Matthew M Jellicoe; Scott J Nichols; Bernard A Callus; Murray V Baker; Peter Barnard; Susan J Berners-Price; James Whelan; George C T Yeoh; Aleksandra Filipovska
Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound.
Carcinogenesis 2008;29(6):1124-33.
2007: Anthony S Humphreys; Aleksandra Filipovska; Susan J Berners-Price; George A Koutsantonis; Brian W Skelton; Allan H White
Gold(I) chloride adducts of 1,3-bis(di-2-pyridylphosphino)propane: synthesis, structural studies and antitumour activity.
Dalton transactions (Cambridge, England : 2003) 2007;(43):4943-50.
2007: Oliver Rackham; Scott J Nichols; Peter J Leedman; Susan J Berners-Price; Aleksandra Filipovska
A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.
Biochemical pharmacology 2007;74(7):992-1002.
2006: Aleksandra Filipovska; Michael P Murphy
Measurement of protein glutathionylation.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2006;Chapter 6():Unit6.11.
2006: Aleksandra Filipovska; Michael P Murphy
Overview of protein glutathionylation.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2006;Chapter 6():Unit6.10.
2005: Thomas R Hurd; Aleksandra Filipovska; Nikola J Costa; Christina C Dahm; Michael P Murphy
Disulphide formation on mitochondrial protein thiols.
Biochemical Society transactions 2005;33(Pt 6):1390-3.
2005: Thomas R Hurd; Nikola J Costa; Christina C Dahm; Samantha M Beer; Stephanie E Brown; Aleksandra Filipovska; Michael P Murphy
Glutathionylation of mitochondrial proteins.
Antioxidants & redox signaling 2005;7(7-8):999-1010.
2005: Aleksandra Filipovska; Geoffrey F Kelso; Stephanie E Brown; Samantha M Beer; Robin A J Smith; Michael P Murphy
Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.
The Journal of biological chemistry 2005;280(25):24113-26.
2005: Meredith F Ross; Geoffrey F Kelso; Frances H Blaikie; Andrew M James; Helena M Cochemé; Aleksandra Filipovska; T Da Ros; Thomas R Hurd; R A J Smith; Michael P Murphy
Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology.
Biochemistry. Biokhimii͡a 2005;70(2):222-30.
2004: Meredith F Ross; Aleksandra Filipovska; Robin A J Smith; Michael J Gait; Michael P Murphy
Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: evidence against direct passage through phospholipid bilayers.
The Biochemical journal 2004;383(Pt. 3):457-68.
2004: Aleksandra Filipovska; Michael Eccles; Robin A J Smith; Michael P Murphy
Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation.
FEBS letters 2004;556(1-3):180-6.
2003: R A J Smith; Geoffrey F Kelso; Frances H Blaikie; Carolyn M Porteous; Elizabeth C Ledgerwood; Gillian Hughes; Andrew M James; Meredith F Ross; Jordi Asin-Cayuela; Helena M Cochemé; Aleksandra Filipovska; Michael P Murphy
Using mitochondria-targeted molecules to study mitochondrial radical production and its consequences.
Biochemical Society transactions 2003;31(Pt 6):1295-9.