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Witold Filipowicz

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Inga Loedige; Gunter Meister; Ragna Sack; Dimos Gaidatzis; Witold Filipowicz
The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.
Julien Béthune; Caroline G Artus-Revel; Witold Filipowicz
Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells.
Nahum Sonenberg; Witold Filipowicz
Retrospective. Aaron Shatkin (1934-2012).

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All Publications

2013: Inga Loedige; Gunter Meister; Ragna Sack; Dimos Gaidatzis; Witold Filipowicz
The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.
Nucleic acids research 2013;41(1):518-32.
2012: Julien Béthune; Caroline G Artus-Revel; Witold Filipowicz
Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells.
EMBO reports 2012;13(8):716-23.
2012: Nahum Sonenberg; Witold Filipowicz
Retrospective. Aaron Shatkin (1934-2012).
Science (New York, N.Y.) 2012;337(6092):309.
2012: Pradipta Kundu; Nahum Sonenberg; Suvendra N Bhattacharyya; Marc R Fabian; Witold Filipowicz
HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA.
Nucleic acids research 2012;40(11):5088-100.
2011: Marina Chekulaeva; Marija Colic; Hansruedi Mathys; Roy Parker; Jakob T Zipprich; Jan Attig; Witold Filipowicz
miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.
Nature structural & molecular biology 2011;18(11):1218-26.
2011: Witold Filipowicz; Helge Grosshans
The liver-specific microRNA miR-122: biology and therapeutic potential.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 2011;67():221-38.
2010: Marina Chekulaeva; Roy Parker; Witold Filipowicz
The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression.
Nucleic acids research 2010;38(19):6673-83.
2010: Jacek Krol; Inga Loedige; Witold Filipowicz
The widespread regulation of microRNA biogenesis, function and decay.
Nature reviews. Genetics 2010;11(9):597-610.
2010: Jacek Krol; Volker Busskamp; Ilona Markiewicz; Michael B Stadler; Sebastian Ribi; Jens Richter; Jens Duebel; Silvia Bicker; Hans Jörg Fehling; Dirk Schübeler; Thomas Oertner; Gerhard Schratt; Miriam Bibel; Botond Roska; Witold Filipowicz
Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs.
Cell 2010;141(4):618-31.
2010: Nicole-Claudia Meisner; Witold Filipowicz
Properties of the regulatory RNA-binding protein HuR and its role in controlling miRNA repression.
Advances in experimental medicine and biology 2010;700():106-23.
2010: Lasse Sinkkonen; Tabea Hugenschmidt; Witold Filipowicz; Petr Svoboda
Dicer is associated with ribosomal DNA chromatin in mammalian cells.
PloS one 2010;5(8):e12175.
2010: Marc Robert Fabian; Nahum Sonenberg; Witold Filipowicz
Regulation of mRNA translation and stability by microRNAs.
Annual review of biochemistry 2010;79():351-79.
2009: Marc R Fabian; Géraldine Mathonnet; Thomas Sundermeier; Hansruedi Mathys; Jakob T Zipprich; Yuri V Svitkin; Fabiola Rivas; Martin Jinek; James Wohlschlegel; Jennifer A Doudna; Chyi-Ying A Chen; Ann-Bin Shyu; John R Yates; Gregory J Hannon; Witold Filipowicz; Thomas F Duchaine; Nahum Sonenberg
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.
Molecular cell 2009;35(6):868-80.
2009: Marina Chekulaeva; Witold Filipowicz
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells.
Current opinion in cell biology 2009;21(3):452-60.
2009: Jakob T Zipprich; Sankar Bhattacharyya; Hansruedi Mathys; Witold Filipowicz
Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.
RNA (New York, N.Y.) 2009;15(5):781-93.
2009: Inga Loedige; Witold Filipowicz
TRIM-NHL proteins take on miRNA regulation.
Cell 2009;136(5):818-20.
2009: Magdalena Sarasin-Filipowicz; Jacek Krol; Ilona Markiewicz; Markus H Heim; Witold Filipowicz
Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy.
Nature medicine 2009;15(1):31-3.
2008: Helge Grosshans; Witold Filipowicz
Proteomics joins the search for microRNA targets.
Cell 2008;134(4):560-2.
2008: Magdalena Sarasin-Filipowicz; Edward J Oakeley; Francois H T Duong; Verena Christen; Luigi Terracciano; Witold Filipowicz; Markus H Heim
Interferon signaling and treatment outcome in chronic hepatitis C.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):7034-9.
2008: Lasse Sinkkonen; Tabea Hugenschmidt; Philipp Berninger; Dimos Gaidatzis; Fabio Mohn; Caroline G Artus-Revel; Mihaela Zavolan; Petr Svoboda; Witold Filipowicz
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells.
Nature structural & molecular biology 2008;15(3):259-67.
2008: Witold Filipowicz; Suvendra N Bhattacharyya; Nahum Sonenberg
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
Nature reviews. Genetics 2008;9(2):102-14.
2008: Helge Grosshans; Witold Filipowicz
Molecular biology: the expanding world of small RNAs.
Nature 2008;451(7177):414-6.
2008: Lukasz Jaskiewicz; Witold Filipowicz
Role of Dicer in posttranscriptional RNA silencing.
Current topics in microbiology and immunology 2008;320():77-97.
2007: Géraldine Mathonnet; Marc R Fabian; Yuri V Svitkin; Armen Parsyan; Laurent Huck; Takayuki Murata; Stefano Biffo; William C Merrick; Edward Darzynkiewicz; Ramesh S Pillai; Witold Filipowicz; Thomas F Duchaine; Nahum Sonenberg
MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F.
Science (New York, N.Y.) 2007;317(5845):1764-7.
2007: Suvendra N Bhattacharyya; Witold Filipowicz
Argonautes and company: sailing against the wind.
Cell 2007;128(6):1027-8.
2007: Ramesh S Pillai; Suvendra N Bhattacharyya; Witold Filipowicz
Repression of protein synthesis by miRNAs: how many mechanisms?
Trends in cell biology 2007;17(3):118-26.
2007: Iwan Beuvink; Fabrice A Kolb; Wolfgang Budach; Arlette Garnier; Joerg Lange; Francois Natt; Uwe Dengler; Jonathan Hall; Witold Filipowicz; Jan Weiler
A novel microarray approach reveals new tissue-specific signatures of known and predicted mammalian microRNAs.
Nucleic acids research 2007;35(7):e52.
2006: Suvendra N Bhattacharyya; Regula Habermacher; Ursula Martine; Ellen I Closs; Witold Filipowicz
Relief of microRNA-mediated translational repression in human cells subjected to stress.
Cell 2006;125(6):1111-24.
2006: Noora Kotaja; Suvendra N Bhattacharyya; Lukasz Jaskiewicz; Sarah Kimmins; Martti Parvinen; Witold Filipowicz; Paolo Sassone-Corsi
The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2647-52.
2006: Suvendra N Bhattacharyya; R Habermacher; U Martine; Ellen I Closs; Witold Filipowicz
Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells.
Cold Spring Harbor symposia on quantitative biology 2006;71():513-21.
2006: Akos Putics; Jutta Slaby; Witold Filipowicz; Alexander E Gorbalenya; John Ziebuhr
ADP-ribose-1"-phosphatase activities of the human coronavirus 229E and SARS coronavirus X domains.
Advances in experimental medicine and biology 2006;581():93-6.
2006: Daniela Schmitter; Jody Filkowski; Alain Sewer; Ramesh S Pillai; Edward J Oakeley; Mihaela Zavolan; Petr Svoboda; Witold Filipowicz
Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells.
Nucleic acids research 2006;34(17):4801-15.
2005: Janice L Pellino; Lukasz Jaskiewicz; Witold Filipowicz; Erik J Sontheimer
ATP modulates siRNA interactions with an endogenous human Dicer complex.
RNA (New York, N.Y.) 2005;11(11):1719-24.
2005: Akos Putics; Witold Filipowicz; Jonathan Hall; Alexander E Gorbalenya; John Ziebuhr
ADP-ribose-1"-monophosphatase: a conserved coronavirus enzyme that is dispensable for viral replication in tissue culture.
Journal of virology 2005;79(20):12721-31.
2005: Astrid D Haase; Lukasz Jaskiewicz; Haidi Zhang; sébastien lainé; Ragna Sack; Anne Gatignol; Witold Filipowicz
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing.
EMBO reports 2005;6(10):961-7.
2005: Ramesh S Pillai; Suvendra N Bhattacharyya; Caroline G Artus; Tabea Zoller; Nicolas Cougot; Eugenia Basyuk; Edouard Bertrand; Witold Filipowicz
Inhibition of translational initiation by Let-7 MicroRNA in human cells.
Science (New York, N.Y.) 2005;309(5740):1573-6.
2005: Witold Filipowicz
RNAi: the nuts and bolts of the RISC machine.
Cell 2005;122(1):17-20.
2005: Witold Filipowicz; Lukasz Jaskiewicz; Fabrice A Kolb; Ramesh S Pillai
Post-transcriptional gene silencing by siRNAs and miRNAs.
Current opinion in structural biology 2005;15(3):331-41.
2005: Eric Westhof; Witold Filipowicz
From RNAi to epigenomes: how RNA rules the world.
Chembiochem : a European journal of chemical biology 2005;6(2):441-3.
2005: Fabrice A Kolb; Haidi Zhang; Katarzyna Jaronczyk; Nasser Tahbaz; Tom C Hobman; Witold Filipowicz
Human dicer: purification, properties, and interaction with PAZ PIWI domain proteins.
Methods in enzymology 2005;392():316-36.
2004: Ramesh S Pillai; Caroline G Artus; Witold Filipowicz
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis.
RNA (New York, N.Y.) 2004;10(10):1518-25.
2004: Haidi Zhang; Fabrice A Kolb; Lukasz Jaskiewicz; Eric Westhof; Witold Filipowicz
Single processing center models for human Dicer and bacterial RNase III.
Cell 2004;118(1):57-68.
2004: Nasser Tahbaz; Fabrice A Kolb; Haidi Zhang; Katarzyna Jaronczyk; Witold Filipowicz; Tom C Hobman
Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer.
EMBO reports 2004;5(2):189-94.
2004: Petr Svoboda; Paula Stein; Witold Filipowicz; Richard M Schultz
Lack of homologous sequence-specific DNA methylation in response to stable dsRNA expression in mouse oocytes.
Nucleic acids research 2004;32(12):3601-6.
2002: Haidi Zhang; Fabrice A Kolb; Vincent Brondani; Eric BILLY; Witold Filipowicz
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP.
The EMBO journal 2002;21(21):5875-85.
2002: Witold Filipowicz; Vanda Pogacić
Biogenesis of small nucleolar ribonucleoproteins.
Current opinion in cell biology 2002;14(3):319-27.
2002: Mark H L Lambermon; Yu Fu; Dominika A Wieczorek Kirk; Marcel Dupasquier; Witold Filipowicz; Zdravko J Lorković
UBA1 and UBA2, two proteins that interact with UBP1, a multifunctional effector of pre-mRNA maturation in plants.
Molecular and cellular biology 2002;22(12):4346-57.
2002: Andreas Hofmann; Sergey Tarasov; Melissa Grella; Sergei Ruvinov; Fahd Nasr; Witold Filipowicz; Alexander Wlodawer
Biophysical characterization of cyclic nucleotide phosphodiesterases.
Biochemical and biophysical research communications 2002;291(4):875-83.
2002: Andreas Hofmann; Melissa Grella; Istvan Botos; Witold Filipowicz; Alexander Wlodawer
Crystal structures of the semireduced and inhibitor-bound forms of cyclic nucleotide phosphodiesterase from Arabidopsis thaliana.
The Journal of biological chemistry 2002;277(2):1419-25.
2001: Eric BILLY; V Brondani; Haidi Zhang; Ulrich Müller; Witold Filipowicz
Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14428-33.
2001: T Wegierski; Eric BILLY; Fahd Nasr; Witold Filipowicz
Bms1p, a G-domain-containing protein, associates with Rcl1p and is required for 18S rRNA biogenesis in yeast.
RNA (New York, N.Y.) 2001;7(9):1254-67.
2000: V Pogacić; F Dragon; Witold Filipowicz
Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10.
Molecular and cellular biology 2000;20(23):9028-40.
2000: Andreas Hofmann; Alexander Zdanov; P Genschik; Sergei Ruvinov; Witold Filipowicz; Alexander Wlodawer
Structure and mechanism of activity of the cyclic phosphodiesterase of Appr>p, a product of the tRNA splicing reaction.
The EMBO journal 2000;19(22):6207-17.
2000: Z J Lorković; Dominika A Wieczorek Kirk; U Klahre; M Hemmings-Mieszczak; Witold Filipowicz
RBP45 and RBP47, two oligouridylate-specific hnRNP-like proteins interacting with poly(A)+ RNA in nuclei of plant cells.
RNA (New York, N.Y.) 2000;6(11):1610-24.
2000: Eric BILLY; T Wegierski; Fahd Nasr; Witold Filipowicz
Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis.
The EMBO journal 2000;19(9):2115-26.
2000: F Dragon; V Pogacić; Witold Filipowicz
In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs.
Molecular and cellular biology 2000;20(9):3037-48.
2000: Fahd Nasr; Witold Filipowicz
Characterization of the Saccharomyces cerevisiae cyclic nucleotide phosphodiesterase involved in the metabolism of ADP-ribose 1",2"-cyclic phosphate.
Nucleic acids research 2000;28(8):1676-83.
2000: Mark H L Lambermon; G G Simpson; Dominika A Wieczorek Kirk; M Hemmings-Mieszczak; U Klahre; Witold Filipowicz
UBP1, a novel hnRNP-like protein that functions at multiple steps of higher plant nuclear pre-mRNA maturation.
The EMBO journal 2000;19(7):1638-49.
2000: Z J Lorković; Dominika A Wieczorek Kirk; Mark H L Lambermon; Witold Filipowicz
Pre-mRNA splicing in higher plants.
Trends in plant science 2000;5(4):160-7.
2000: G J Palm; Eric BILLY; Witold Filipowicz; A Wlodawer
Crystal structure of RNA 3'-terminal phosphate cyclase, a ubiquitous enzyme with unusual topology.
Structure (London, England : 1993) 2000;8(1):13-23.
1999: Eric BILLY; daniel Hess; Jan Hofsteenge; Witold Filipowicz
Characterization of the adenylation site in the RNA 3'-terminal phosphate cyclase from Escherichia coli.
The Journal of biological chemistry 1999;274(49):34955-60.
1999: Witold Filipowicz; P Pelczar; Vanda Pogacic; F Dragon
Structure and biogenesis of small nucleolar RNAs acting as guides for ribosomal RNA modification.
Acta biochimica Polonica 1999;46(2):377-89.
1998: C Domon; Z J Lorković; J Valcárcel; Witold Filipowicz
Multiple forms of the U2 small nuclear ribonucleoprotein auxiliary factor U2AF subunits expressed in higher plants.
The Journal of biological chemistry 1998;273(51):34603-10.
1998: P Genschik; K Drabikowski; Witold Filipowicz
Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon.
The Journal of biological chemistry 1998;273(39):25516-26.
1998: P Pelczar; Witold Filipowicz
The host gene for intronic U17 small nucleolar RNAs in mammals has no protein-coding potential and is a member of the 5'-terminal oligopyrimidine gene family.
Molecular and cellular biology 1998;18(8):4509-18.
1998: Witold Filipowicz; Eric BILLY; K Drabikowski; P Genschik
Cyclases of the 3'-terminal phosphate in RNA: a new family of RNA processing enzymes conserved in eucarya, bacteria and archaea.
Acta biochimica Polonica 1998;45(4):895-906.
1997: P Genschik; J Hall; Witold Filipowicz
Cloning and characterization of the Arabidopsis cyclic phosphodiesterase which hydrolyzes ADP-ribose 1'',2''-cyclic phosphate and nucleoside 2',3'-cyclic phosphates.
The Journal of biological chemistry 1997;272(20):13211-9.
1997: P Genschik; Eric BILLY; M Swianiewicz; Witold Filipowicz
The human RNA 3'-terminal phosphate cyclase is a member of a new family of proteins conserved in Eucarya, Bacteria and Archaea.
The EMBO journal 1997;16(10):2955-67.
1996: G G Simpson; Witold Filipowicz
Splicing of precursors to mRNA in higher plants: mechanism, regulation and sub-nuclear organisation of the spliceosomal machinery.
Plant molecular biology 1996;32(1-2):1-41.
1996: Tamás Kiss; Marie-Line Bortolin; Witold Filipowicz
Characterization of the intron-encoded U19 RNA, a new mammalian small nucleolar RNA that is not associated with fibrillarin.
Molecular and cellular biology 1996;16(4):1391-400.
1996: H X Liu; Witold Filipowicz
Mapping of branchpoint nucleotides in mutant pre-mRNAs expressed in plant cells.
The Plant journal : for cell and molecular biology 1996;9(3):381-9.
1996: M Gniadkowski; M Hemmings-Mieszczak; U Klahre; H X Liu; Witold Filipowicz
Characterization of intronic uridine-rich sequence elements acting as possible targets for nuclear proteins during pre-mRNA splicing in Nicotiana plumbaginifolia.
Nucleic acids research 1996;24(4):619-27.
1995: David Heard; Witold Filipowicz; J P Marques; Klaus Palme; J M Gualberto
An upstream U-snRNA gene-like promoter is required for transcription of the Arabidopsis thaliana 7SL RNA gene.
Nucleic acids research 1995;23(11):1970-6.
1995: T Kiss; Witold Filipowicz
Exonucleolytic processing of small nucleolar RNAs from pre-mRNA introns.
Genes & development 1995;9(11):1411-24.
1995: U Klahre; M Hemmings-Mieszczak; Witold Filipowicz
Extreme heterogeneity of polyadenylation sites in mRNAs encoding chloroplast RNA-binding proteins in Nicotiana plumbaginifolia.
Plant molecular biology 1995;28(3):569-74.
1995: H X Liu; G J Goodall; Ryszard Kole; Witold Filipowicz
Effects of secondary structure on pre-mRNA splicing: hairpins sequestering the 5' but not the 3' splice site inhibit intron processing in Nicotiana plumbaginifolia.
The EMBO journal 1995;14(2):377-88.
1994: D J Leader; S Connelly; Witold Filipowicz; J W Brown
Characterisation and expression of a maize U3 snRNA gene.
Biochimica et biophysica acta 1994;1219(1):145-7.
1994: S Connelly; C Marshallsay; D Leader; J W Brown; Witold Filipowicz
Small nuclear RNA genes transcribed by either RNA polymerase II or RNA polymerase III in monocot plants share three promoter elements and use a strategy to regulate gene expression different from that used by their dicot plant counterparts.
Molecular and cellular biology 1994;14(9):5910-9.
1993: S Connelly; Witold Filipowicz
Activity of chimeric U small nuclear RNA (snRNA)/mRNA genes in transfected protoplasts of Nicotiana plumbaginifolia: U snRNA 3'-end formation and transcription initiation can occur independently in plants.
Molecular and cellular biology 1993;13(10):6403-15.
1993: David Heard; T Kiss; Witold Filipowicz
Both Arabidopsis TATA binding protein (TBP) isoforms are functionally identical in RNA polymerase II and III transcription in plant cells: evidence for gene-specific changes in DNA binding specificity of TBP.
The EMBO journal 1993;12(9):3519-28.
1993: Witold Filipowicz; T Kiss
Structure and function of nucleolar snRNPs.
Molecular biology reports 1993;18(2):149-56.
1993: T Kiss; Witold Filipowicz
Small nucleolar RNAs encoded by introns of the human cell cycle regulatory gene RCC1.
The EMBO journal 1993;12(7):2913-20.
1993: D Edoh; T Kiss; Witold Filipowicz
Activity of U-snRNA genes with modified placement of promoter elements in transfected protoplasts and stably transformed tobacco.
Nucleic acids research 1993;21(7):1533-40.
1993: D Leader; S Connelly; Witold Filipowicz; Robbie Waugh; J W Brown
Differential expression of U5snRNA gene variants in maize (Zea mays) protoplasts.
Plant molecular biology 1993;21(1):133-43.
1992: C J Hofmann; C Marshallsay; F Waibel; Witold Filipowicz
Characterization of the genes encoding U4 small nuclear RNAs in Arabidopsis thaliana.
Molecular biology reports 1992;17(1):21-8.
1992: T Kiss; C Marshallsay; Witold Filipowicz
7-2/MRP RNAs in plant and mammalian cells: association with higher order structures in the nucleolus.
The EMBO journal 1992;11(10):3737-46.
1992: C Marshallsay; S Connelly; Witold Filipowicz
Characterization of the U3 and U6 snRNA genes from wheat: U3 snRNA genes in monocot plants are transcribed by RNA polymerase III.
Plant molecular biology 1992;19(6):973-83.
1992: M Mieszczak; U Klahre; J H Levy; G J Goodall; Witold Filipowicz
Multiple plant RNA binding proteins identified by PCR: expression of cDNAs encoding RNA binding proteins targeted to chloroplasts in Nicotiana plumbaginifolia.
Molecular & general genetics : MGG 1992;234(3):390-400.
1992: T Kiss; Witold Filipowicz
Evidence against a mitochondrial location of the 7-2/MRP RNA in mammalian cells.
Cell 1992;70(1):11-6.
1991: G J Goodall; Witold Filipowicz
Different effects of intron nucleotide composition and secondary structure on pre-mRNA splicing in monocot and dicot plants.
The EMBO journal 1991;10(9):2635-44.
1991: T Kiss; C Marshallsay; Witold Filipowicz
Alteration of the RNA polymerase specificity of U3 snRNA genes during evolution and in vitro.
Cell 1991;65(3):517-26.
1990: C Marshallsay; T Kiss; Witold Filipowicz
Nucleotide sequence and expression of a new Arabidopsis U2 snRNA gene.
Nucleic acids research 1990;18(17):5280.
1990: F Waibel; Witold Filipowicz
RNA-polymerase specificity of transcription of Arabidopsis U snRNA genes determined by promoter element spacing.
Nature 1990;346(6280):199-202.
1990: C Marshallsay; T Kiss; Witold Filipowicz
Amplification of plant U3 and U6 snRNA gene sequences using primers specific for an upstream promoter element and conserved intragenic regions.
Nucleic acids research 1990;18(12):3459-66.
1990: F Waibel; Witold Filipowicz
U6 snRNA genes of Arabidopsis are transcribed by RNA polymerase III but contain the same two upstream promoter elements as RNA polymerase II-transcribed U-snRNA genes.
Nucleic acids research 1990;18(12):3451-8.
1990: G J Goodall; Witold Filipowicz
The minimum functional length of pre-mRNA introns in monocots and dicots.
Plant molecular biology 1990;14(5):727-33.
1990: F Waibel; Witold Filipowicz
The spacing between two promoter elements determines RNA polymerase specificity during transcription of U small nuclear RNA genes of Arabidopsis.
Molecular biology reports 1990;14(2-3):149.
1990: Witold Filipowicz; O Vicente
RNA 3'-terminal phosphate cyclase from HeLa cells.
Methods in enzymology 1990;181():499-510.
1990: Witold Filipowicz; T Kiss; C Marshallsay; F Waibel
U-snRNA genes, U-snRNAs and U-snRNPs of higher plants.
Molecular biology reports 1990;14(2-3):125-9.
1990: G J Goodall; K Wiebauer; Witold Filipowicz
Analysis of pre-mRNA processing in transfected plant protoplasts.
Methods in enzymology 1990;181():148-61.
1990: G Goodall; J Levy; M Mieszczak; Witold Filipowicz
Plant RNA-binding proteins.
Molecular biology reports 1990;14(2-3):137.
1989: P Vankan; Witold Filipowicz
A U-snRNA gene-specific upstream element and a -30 'TATA box' are required for transcription of the U2 snRNA gene of Arabidopsis thaliana.
The EMBO journal 1989;8(12):3875-82.
1989: G J Goodall; Witold Filipowicz
The AU-rich sequences present in the introns of plant nuclear pre-mRNAs are required for splicing.
Cell 1989;58(3):473-83.
1988: P Vankan; D Edoh; Witold Filipowicz
Structure and expression of the U5 snRNA gene of Arabidopsis thaliana. Conserved upstream sequence elements in plant U-RNA genes.
Nucleic acids research 1988;16(22):10425-40.
1988: O Vicente; Witold Filipowicz
Purification of RNA 3'-terminal phosphate cyclase from HeLa cells. Covalent modification of the enzyme with different nucleotides.
European journal of biochemistry / FEBS 1988;176(2):431-9.
1988: K Wiebauer; J J Herrero; Witold Filipowicz
Nuclear pre-mRNA processing in plants: distinct modes of 3'-splice-site selection in plants and animals.
Molecular and cellular biology 1988;8(5):2042-51.
1988: P Vankan; Witold Filipowicz
Structure of U2 snRNA genes of Arabidopsis thaliana and their expression in electroporated plant protoplasts.
The EMBO journal 1988;7(3):791-9.
1987: K Tyc; C Kellenberger; Witold Filipowicz
Purification and characterization of wheat germ 2',3'-cyclic nucleotide 3'-phosphodiesterase.
The Journal of biological chemistry 1987;262(27):12994-3000.
1985: Witold Filipowicz; K Strugala; M Konarska; A J Shatkin
Cyclization of RNA 3'-terminal phosphate by cyclase from HeLa cells proceeds via formation of N(3')pp(5')A activated intermediate.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(5):1316-20.
1984: K Tyc; M Konarska; H J Gross; Witold Filipowicz
Multiple ribosome binding to the 5'-terminal leader sequence of tobacco mosaic virus RNA. Assembly of an 80S ribosome X mRNA complex at the AUU codon.
European journal of biochemistry / FEBS 1984;140(3):503-11.
1983: Witold Filipowicz; M Konarska; H J Gross; A J Shatkin
RNA 3'-terminal phosphate cyclase activity and RNA ligation in HeLa cell extract.
Nucleic acids research 1983;11(5):1405-18.
1983: K Tyc; Y Kikuchi; M Konarska; Witold Filipowicz; Hans J Gross
Ligation of endogenous tRNA 3' half molecules to their corresponding 5' halves via 2'-phosphomonoester,3',5'-phosphodiester bonds in extracts of Chlamydomonas.
The EMBO journal 1983;2(4):605-10.
1982: Y Kikuchi; K Tyc; Witold Filipowicz; H L Sänger; H J Gross
Circularization of linear viroid RNA via 2'-phosphomonoester, 3', 5'-phosphodiester bonds by a novel type of RNA ligase from wheat germ and Chlamydomonas.
Nucleic acids research 1982;10(23):7521-9.
1982: M Konarska; Witold Filipowicz; H J Gross
RNA ligation via 2'-phosphomonoester, 3'5'-phosphodiester linkage: requirement of 2',3'-cyclic phosphate termini and involvement of a 5'-hydroxyl polynucleotide kinase.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(5):1474-8.
1981: M Konarska; Witold Filipowicz; H Domdey; H J Gross
Formation of a 2'-phosphomonoester, 3',5'-phosphodiester linkage by a novel RNA ligase in wheat germ.
Nature 1981;293(5828):112-6.
1981: M Konarska; Witold Filipowicz; H Domdey; H J Gross
Binding of ribosomes to linear and circular forms of the 5'-terminal leader fragment of tobacco-mosaic-virus RNA.
European journal of biochemistry / FEBS 1981;114(2):221-7.