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Dmitri Filippov

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Gerbrand J van der Heden van Noort; Gijsbert A van der Marel; Herman S Overkleeft; Catherine H Schein; Dmitri V Filippov
A general synthetic method toward uridylylated picornavirus VPg proteins.
Hans A V Kistemaker; Herman S Overkleeft; Gerbrand J van der Heden van Noort; Gijsbert A van der Marel; Dmitri V Filippov
Stereoselective ribosylation of amino acids.
Richard Virgen-Slane; Gerbrand J van der Heden van Noort; Wayne Chou; Dmitri V Filippov; Kerry D Fitzgerald; Paul D Gershon; Tuan Ngo; Janet M Rozovics; Bert L Semler
An RNA virus hijacks an incognito function of a DNA repair enzyme.

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All Publications

2013: Gerbrand J van der Heden van Noort; Gijsbert A van der Marel; Herman S Overkleeft; Catherine H Schein; Dmitri V Filippov
A general synthetic method toward uridylylated picornavirus VPg proteins.
Journal of peptide science : an official publication of the European Peptide Society 2013;19(6):333-6.
2013: Hans A V Kistemaker; Herman S Overkleeft; Gerbrand J van der Heden van Noort; Gijsbert A van der Marel; Dmitri V Filippov
Stereoselective ribosylation of amino acids.
Organic letters 2013;15(9):2306-9.
2012: Richard Virgen-Slane; Gerbrand J van der Heden van Noort; Wayne Chou; Dmitri V Filippov; Kerry D Fitzgerald; Paul D Gershon; Tuan Ngo; Janet M Rozovics; Bert L Semler
An RNA virus hijacks an incognito function of a DNA repair enzyme.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(36):14634-9.
2012: Gerbrand J van der Heden van Noort; Gijsbert A van der Marel; Pieter van Delft; Nico J Meeuwenoord; Herman S Overkleeft; Dmitri V Filippov
Fully automated sequential solid phase approach towards viral RNA-nucleopeptides.
Chemical communications (Cambridge, England) 2012;48(65):8093-5.
2012: W F J Hogendorf; johannes huebner; Andrea Kropec; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov; Jeroen D C Codée
Light fluorous synthesis of glucosylated glycerol teichoic acids.
Carbohydrate research 2012;356():142-51.
2012: Wouter F J Hogendorf; Lucien N Lameijer; Herman S Overkleeft; Thomas J M Beenakker; Jeroen D C Codée; Dmitri V Filippov; Gijsbert A van der Marel
Fluorous linker facilitated synthesis of teichoic acid fragments.
Organic letters 2012;14(3):848-51.
2012: Catherine H Schein; Gerbrand J van der Heden van Noort; David M Bowen; Kyung Choi; Jessica A Lewis; Wenzhe Lu; Aniko Paul; Dmitri V Filippov
Physicochemical property consensus sequences for functional analysis, design of multivalent antigens and targeted antivirals.
BMC bioinformatics 2012;13 Suppl 13():S9.
2012: Gijs G P Zom; Dmitri V Filippov; Selina Khan; Ferry Ossendorp
TLR ligand-peptide conjugate vaccines: toward clinical application.
Advances in immunology 2012;114():177-201.
2011: Wouter F J Hogendorf; Johannes Huebner; Andrea Kropec; Diana Laverde; Nico J Meeuwenoord; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov; Jeroen D C Codée
Automated solid phase synthesis of teichoic acids.
Chemical communications (Cambridge, England) 2011;47(31):8961-3.
2011: Gerbrand J van der Heden van Noort; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov
Ribosylation of adenosine: an orthogonally protected building block for the synthesis of ADP-ribosyl oligomers.
Organic letters 2011;13(11):2920-3.
2010: Pieter van Delft; Nico J Meeuwenoord; Sascha Hoogendoorn; Jasper Dinkelaar; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov
Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite.
Organic letters 2010;12(23):5486-9.
2010: Gerbrand J van der Heden van Noort; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov
Synthesis of nucleotidylated poliovirus VPg proteins.
The Journal of organic chemistry 2010;75(16):5733-6.
2010: Catherine H Schein; Numan Oezguen; Gerbrand J van der Heden van Noort; Dmitri V Filippov; Aniko Paul; Eric Kumar; Werner Braun
NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU).
Peptides 2010;31(8):1441-8.
2010: Gerbrand J van der Heden van Noort; Maarten G van der Horst; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov
Synthesis of mono-ADP-ribosylated oligopeptides using ribosylated amino acid building blocks.
Journal of the American Chemical Society 2010;132(14):5236-40.
2009: Jimmy J Weterings; Selina Khan; Gerbrand J van der Heden van Noort; Cornelis J M Melief; Herman S Overkleeft; Sjoerd H van der burg; Ferry Ossendorp; Gijsbert A van der Marel; Dmitri V Filippov
2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation.
Bioorganic & medicinal chemistry letters 2009;19(8):2249-51.
2009: Selina Khan; Jimmy J Weterings; Cedrik Michael Britten; Ana R de Jong; Dirk Graafland; Cornelis J M Melief; Sjoerd H van der burg; Gijs van der Marel; Herman S Overkleeft; Dmitri V Filippov; Ferry Ossendorp
Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells.
Molecular immunology 2009;46(6):1084-91.
2009: Jimmy J Weterings; Selina Khan; Jan Wouter Drijfhout; Ferry Ossendorp; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov
Synthesis of modified and hybrid protein derived biopolymers.
Advances in experimental medicine and biology 2009;611():141-2.
2008: Erik Malta; Carlo P Verhagen; Geri F Moolenaar; Dmitri V Filippov; Gijsbert A van der Marel; Nora Goosen
Functions of base flipping in E. coli nucleotide excision repair.
DNA repair 2008;7(10):1647-58.
2007: Martijn Verdoes; Ulrik Hillaert; Bogdan I Florea; Myra Sae-Heng; Martijn D P Risseeuw; Dmitri V Filippov; Gijsbert A van der Marel; Herman S Overkleeft
Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes.
Bioorganic & medicinal chemistry letters 2007;17(22):6169-71.
2007: Selina Khan; Martijn Bijker; Jimmy J Weterings; Hans J Tanke; Gosse J Adema; Thorbald van Hall; Jan Wouter Drijfhout; Cornelis J M Melief; Herman S Overkleeft; Gijsbert A van der Marel; Dmitri V Filippov; Sjoerd H van der burg; Ferry Ossendorp
Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells.
The Journal of biological chemistry 2007;282(29):21145-59.
2007: Saskia Houwing; Leonie Marjan Kamminga; Eugene Berezikov; Daniela Cronembold; Angélique Girard; Hans van den Elst; Dmitri V Filippov; Heiko Blaser; erez raz; Cecilia B Moens; Ronald H Plasterk; Gregory J Hannon; Bruce W Draper; René F Ketting
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.
Cell 2007;129(1):69-82.
2007: Prashant Agrawal; Mathias W Hofmann; Nico J Meeuwenoord; Dmitri V Filippov; Holger Stalz; Frans B Hulsbergen; Dieter Langosch; Herman S Overkleeft; Huub de Groot
Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptides.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(2):75-80.
2006: Martijn Verdoes; Bogdan I Florea; Victoria Menendez-Benito; Christa Maynard; Martin D Witte; Wouter A van der Linden; Adrianus M C H van den Nieuwendijk; Tanja Hofmann; Celia R Berkers; Fijs W B van Leeuwen; Tom A M Groothuis; Michiel A Leeuwenburgh; Huib Ovaa; Jacques Neefjes; Dmitri V Filippov; Gijsbert A van der Marel; Nico P Dantuma; Herman S Overkleeft
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.
Chemistry & biology 2006;13(11):1217-26.
2006: Nicole M A J Kriek; Nico J Meeuwenoord; Hans van den Elst; Hans A Heus; Gijsbert A van der Marel; Dmitri V Filippov
Chemical synthesis of picornaviral protein primers of RNA replication.
Organic & biomolecular chemistry 2006;4(19):3576-86.
2006: Adriaan W Tuin; Gregg Siegal; Gijsbert A van der Marel; Herman S Overkleeft; Dmitri V Filippov
Facile synthesis and application of uniformly 13C, 15N-labeled phosphotyrosine for ligand binding studies.
Bioorganic & medicinal chemistry letters 2006;16(14):3806-8.
2006: Jimmy J Weterings; Selina Khan; Gerbrand J van der Heden; Jan Wouter Drijfhout; Cornelis J M Melief; Herman S Overkleeft; Sjoerd H van der burg; Ferry Ossendorp; Gijsbert A van der Marel; Dmitri V Filippov
Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: towards synthetic epitope-based vaccines.
Bioorganic & medicinal chemistry letters 2006;16(12):3258-61.
2005: Gerard Voerman; Silvia Cavalli; Gijsbert A van der Marel; Wolfgang Pfleiderer; Jacques H van Boom; Dmitri V Filippov
1,3-Dimethyllumazine derivatives from Limnatis nilotica.
Journal of natural products 2005;68(6):938-41.
2005: Sophie Vanwetswinkel; Robert J Heetebrij; John van Duynhoven; Johan G Hollander; Dmitri V Filippov; Philip J Hajduk; Gregg Siegal
TINS, target immobilized NMR screening: an efficient and sensitive method for ligand discovery.
Chemistry & biology 2005;12(2):207-16.
2004: Marij J P Welters; Dmitri V Filippov; Susan J F van den Eeden; Kees L M C Franken; Jan Nouta; Rob Valentijn; Gijsbert A van der Marel; Herman S Overkleeft; Grayson Lipford; Rienk Offringa; Cornelis J M Melief; Jacques H van Boom; Sjoerd H van der burg; Jan Wouter Drijfhout
Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model.
Vaccine 2004;23(3):305-11.
2003: Sorin Luca; Jim F White; Awinder K Sohal; Dmitri V Filippov; Jacques H van Boom; Reinhard Grisshammer; Marc Baldus
The conformation of neurotensin bound to its G protein-coupled receptor.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10706-11.
2003: Peter C de Visser; N M A J Kriek; Peter A V van Hooft; Ann Van Schepdael; Dmitri V Filippov; Gijsbert A van der Marel; Herman S Overkleeft; Jacques H van Boom; Daan Noort
Solid-phase synthesis of polymyxin B1 and analogues via a safety-catch approach.
The journal of peptide research : official journal of the American Peptide Society 2003;61(6):298-306.
2003: Dmitri V Sakharov; A F H Jie; Dmitri V Filippov; M E A Bekkers; Jacques H van Boom; Dingeman C Rijken
Binding and retention of polycationic peptides and dendrimers in the vascular wall.
FEBS letters 2003;537(1-3):6-10.
2002: Danny Burg; Liesbeth Hameetman; Dmitri V Filippov; Gijsbert A van der Marel; Gerard J Mulder
Inhibition of glutathione S-transferase in rat hepatocytes by a glycine-tetrazole modified S-alkyl-GSH analogue.
Bioorganic & medicinal chemistry letters 2002;12(12):1579-82.
2002: Danny Burg; Dmitri V Filippov; Ralph Hermanns; Gijsbert A van der Marel; Jacques H van Boom; Gerard J Mulder
Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors.
Bioorganic & medicinal chemistry 2002;10(1):195-205.
2001: Sorin Luca; Dmitri V Filippov; Jacques H van Boom; H Oschkinat; Huub J M de Groot; Marc Baldus
Secondary chemical shifts in immobilized peptides and proteins: a qualitative basis for structure refinement under magic angle spinning.
Journal of biomolecular NMR 2001;20(4):325-31.
1998: Aniko V Paul; Jacques H van Boom; Dmitri V Filippov; Eckard Wimmer
Protein-primed RNA synthesis by purified poliovirus RNA polymerase.
Nature 1998;393(6682):280-4.