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Anthony Fink

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Phenomena

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Chemicals & Drugs

Physiology

Protein Folding

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Co-Publications
Name
65
Uversky, Vladimir
15
Doniach, Sebastian
15
Li, Jie
13
Munishkina, Larissa
12
Millett, Ian
11
Zhu, Min
10
Khurana, Ritu
8
Yamin, Ghiam
8
Hong, Dong-Pyo
7
Gillespie, Joel
7
Souillac, Pierre
5
Ahmad, Atta
5
Segel, Daniel
5
Goers, John
5
Goto, Yuji

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Publications

TOP 3
Meng Xiaoyun; Munishkina Larissa A; Fink Anthony L; Uversky Vladimir N
Molecular mechanisms underlying the flavonoid-induced inhibition of alpha-synuclein fibrillation.
Munishkina L A; Fink A L; Uversky V N
Accelerated fibrillation of alpha-synuclein induced by the combined action of macromolecular crowding and factors inducing partial folding.
Zhou Wenbo; Gallagher Amy; Hong Dong-Pyo; Long Chunmei; Fink Anthony L; Uversky Vladimir N
At low concentrations, 3,4-dihydroxyphenylacetic acid (DOPAC) binds non-covalently to alpha-synuclein and prevents its fibrillation.

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All Publications

2009: Meng Xiaoyun; Munishkina Larissa A; Fink Anthony L; Uversky Vladimir N
Molecular mechanisms underlying the flavonoid-induced inhibition of alpha-synuclein fibrillation.
Biochemistry 2009;48(34):8206-24.
2009: Munishkina L A; Fink A L; Uversky V N
Accelerated fibrillation of alpha-synuclein induced by the combined action of macromolecular crowding and factors inducing partial folding.
Current Alzheimer research 2009;6(3):252-60.
2009: Zhou Wenbo; Gallagher Amy; Hong Dong-Pyo; Long Chunmei; Fink Anthony L; Uversky Vladimir N
At low concentrations, 3,4-dihydroxyphenylacetic acid (DOPAC) binds non-covalently to alpha-synuclein and prevents its fibrillation.
Journal of molecular biology 2009;388(3):597-610.
2009: Hong Dong-Pyo; Fink Anthony L; Uversky Vladimir N
Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation?
Biochimica et biophysica acta 2009;1794(2):282-90.
2008: Hong Dong-Pyo; Fink Anthony L; Uversky Vladimir N
Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein.
Journal of molecular biology 2008;383(1):214-23.
2008: Ulrih Natasa Poklar; Barry Christopher H; Fink Anthony L
Impact of Tyr to Ala mutations on alpha-synuclein fibrillation and structural properties.
Biochimica et biophysica acta 2008;1782(10):581-5.
2008: Meng Xiaoyun; Fink Anthony L; Uversky Vladimir N
The effect of membranes on the in vitro fibrillation of an amyloidogenic light-chain variable-domain SMA.
Journal of molecular biology 2008;381(4):989-99.
2008: Munishkina Larissa A; Ahmad Atta; Fink Anthony L; Uversky Vladimir N
Guiding protein aggregation with macromolecular crowding.
Biochemistry 2008;47(34):8993-9006.
2008: Hu Dongmei; Qin Zhijie; Xue Bin; Fink Anthony L; Uversky Vladimir N
Effect of methionine oxidation on the structural properties, conformational stability, and aggregation of immunoglobulin light chain LEN.
Biochemistry 2008;47(33):8665-77.
2008: Lakshminarasimhan Mahadevan; Maldonado Marien T; Zhou Wenbo; Fink Anthony L; Wilson Mark A
Structural impact of three Parkinsonism-associated missense mutations on human DJ-1.
Biochemistry 2008;47(5):1381-92.
2007: Qin Zhijie; Hu Dongmei; Han Shubo; Hong Dong-Pyo; Fink Anthony L
Role of different regions of alpha-synuclein in the assembly of fibrils.
Biochemistry 2007;46(46):13322-30.
2007: Munishkina Larissa A; Fink Anthony L
Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins.
Biochimica et biophysica acta 2007;1768(8):1862-85.
2007: Qin Zhijie; Hu Dongmei; Zhu Min; Fink Anthony L
Structural characterization of the partially folded intermediates of an immunoglobulin light chain leading to amyloid fibrillation and amorphous aggregation.
Biochemistry 2007;46(11):3521-31.
2007: Martinez Zak; Zhu Min; Han Shubo; Fink Anthony L
GM1 specifically interacts with alpha-synuclein and inhibits fibrillation.
Biochemistry 2007;46(7):1868-77.
2007: Qin Zhijie; Hu Dongmei; Han Shubo; Reaney Stephen H; Di Monte Donato A; Fink Anthony L
Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation.
The Journal of biological chemistry 2007;282(8):5862-70.
2006: Fink Anthony L
The aggregation and fibrillation of alpha-synuclein.
Accounts of chemical research 2006;39(9):628-34.
2006: Hong Dong-Pyo; Ahmad Atta; Fink Anthony L
Fibrillation of human insulin A and B chains.
Biochemistry 2006;45(30):9342-53.
2006: Zhu Min; Qin Zhi-Jie; Hu Dongmei; Munishkina Larissa A; Fink Anthony L
Alpha-synuclein can function as an antioxidant preventing oxidation of unsaturated lipid in vesicles.
Biochemistry 2006;45(26):8135-42.
2006: Zhou Wenbo; Zhu Min; Wilson Mark A; Petsko Gregory A; Fink Anthony L
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.
Journal of molecular biology 2006;356(4):1036-48.
2006: Dusa Alexandra; Kaylor Joanna; Edridge Shauna; Bodner Nika; Hong Dong-Pyo; Fink Anthony L
Characterization of oligomers during alpha-synuclein aggregation using intrinsic tryptophan fluorescence.
Biochemistry 2006;45(8):2752-60.
2005: Hong Dong-Pyo; Fink Anthony L
Independent heterologous fibrillation of insulin and its B-chain peptide.
Biochemistry 2005;44(50):16701-9.
2005: Ahmad Atta; Uversky Vladimir N; Hong Dongpyo; Fink Anthony L
Early events in the fibrillation of monomeric insulin.
The Journal of biological chemistry 2005;280(52):42669-75.
2005: Liu I-Hsuan; Uversky Vladimir N; Munishkina Larissa A; Fink Anthony L; Halfter Willi; Cole Gregory J
Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation.
Glycobiology 2005;15(12):1320-31.
2005: Kaylor Joanna; Bodner Nika; Edridge Shauna; Yamin Ghiam; Hong Dong-Pyo; Fink Anthony L
Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.
Journal of molecular biology 2005;353(2):357-72.
2005: Yamin Ghiam; Munishkina Larissa A; Karymov Mikhail A; Lyubchenko Yuri L; Uversky Vladimir N; Fink Anthony L
Forcing nonamyloidogenic beta-synuclein to fibrillate.
Biochemistry 2005;44(25):9096-107.
2005: Uversky Vladimir N; Yamin Ghiam; Munishkina Larissa A; Karymov Mikhail A; Millett Ian S; Doniach Sebastian; Lyubchenko Yuri L; Fink Anthony L
Effects of nitration on the structure and aggregation of alpha-synuclein.
Brain research. Molecular brain research 2005;134(1):84-102.
2005: Fink Anthony L
Natively unfolded proteins.
Current opinion in structural biology 2005;15(1):35-41.
2005: Glaser Charles B; Yamin Ghiam; Uversky Vladimir N; Fink Anthony L
Methionine oxidation, alpha-synuclein and Parkinson's disease.
Biochimica et biophysica acta 2005;1703(2):157-69.
2004: Li Jie; Zhu Min; Rajamani Sudha; Uversky Vladimir N; Fink Anthony L
Rifampicin inhibits alpha-synuclein fibrillation and disaggregates fibrils.
Chemistry & biology 2004;11(11):1513-21.
2004: Munishkina Larissa A; Cooper Elisa M; Uversky Vladimir N; Fink Anthony L
The effect of macromolecular crowding on protein aggregation and amyloid fibril formation.
Journal of molecular recognition : JMR 2004;17(5):456-64.
2004: Munishkina Larissa A; Fink Anthony L; Uversky Vladimir N
Conformational prerequisites for formation of amyloid fibrils from histones.
Journal of molecular biology 2004;342(4):1305-24.
2004: Zhu Min; Rajamani Sudha; Kaylor Joanna; Han Shubo; Zhou Feimeng; Fink Anthony L
The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils.
The Journal of biological chemistry 2004;279(26):26846-57.
2004: Li Jie; Zhu Min; Manning-Bog Amy B; Di Monte Donato A; Fink Anthony L
Dopamine and L-dopa disaggregate amyloid fibrils: implications for Parkinson's and Alzheimer's disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(9):962-4.
2004: Zhu Min; Han Shubo; Zhou Feimeng; Carter Sue A; Fink Anthony L
Annular oligomeric amyloid intermediates observed by in situ atomic force microscopy.
The Journal of biological chemistry 2004;279(23):24452-9.
2004: Uversky Vladimir N; Fink Anthony L
Conformational constraints for amyloid fibrillation: the importance of being unfolded.
Biochimica et biophysica acta 2004;1698(2):131-53.
2004: Hokenson Mark J; Uversky Vladimir N; Goers John; Yamin Ghiam; Munishkina Larissa A; Fink Anthony L
Role of individual methionines in the fibrillation of methionine-oxidized alpha-synuclein.
Biochemistry 2004;43(15):4621-33.
2004: Ahmad Atta; Millett Ian S; Doniach Sebastian; Uversky Vladimir N; Fink Anthony L
Stimulation of insulin fibrillation by urea-induced intermediates.
The Journal of biological chemistry 2004;279(15):14999-5013.
2004: Munishkina Larissa A; Henriques Jeremy; Uversky Vladimir N; Fink Anthony L
Role of protein-water interactions and electrostatics in alpha-synuclein fibril formation.
Biochemistry 2004;43(11):3289-300.
2003: Ahmad Atta; Millett Ian S; Doniach Sebastian; Uversky Vladimir N; Fink Anthony L
Partially folded intermediates in insulin fibrillation.
Biochemistry 2003;42(39):11404-16.
2003: Zhu Min; Li Jie; Fink Anthony L
The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation.
The Journal of biological chemistry 2003;278(41):40186-97.
2003: Khurana Ritu; Ionescu-Zanetti Cristian; Pope Maighdlin; Li Jie; Nielson Liza; Ramírez-Alvarado Marina; Regan Lynn; Fink Anthony L; Carter Sue A
A general model for amyloid fibril assembly based on morphological studies using atomic force microscopy.
Biophysical journal 2003;85(2):1135-44.
2003: Goers John; Manning-Bog Amy B; McCormack Alison L; Millett Ian S; Doniach Sebastian; Di Monte Donato A; Uversky Vladimir N; Fink Anthony L
Nuclear localization of alpha-synuclein and its interaction with histones.
Biochemistry 2003;42(28):8465-71.
2003: Berriman John; Serpell Louise C; Oberg Keith A; Fink Anthony L; Goedert Michel; Crowther R Anthony
Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):9034-8.
2003: Souillac Pierre O; Uversky Vladimir N; Fink Anthony L
Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN.
Biochemistry 2003;42(26):8094-104.
2003: Yamin Ghiam; Glaser Charles B; Uversky Vladimir N; Fink Anthony L
Certain metals trigger fibrillation of methionine-oxidized alpha-synuclein.
The Journal of biological chemistry 2003;278(30):27630-5.
2003: Khurana Ritu; Souillac Pierre O; Coats Alisa C; Minert Lauren; Ionescu-Zanetti Cristian; Carter Sue A; Solomon Alan; Fink Anthony L
A model for amyloid fibril formation in immunoglobulin light chains based on comparison of amyloidogenic and benign proteins and specific antibody binding.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2003;10(2):97-109.
2003: Yamin Ghiam; Uversky Vladimir N; Fink Anthony L
Nitration inhibits fibrillation of human alpha-synuclein in vitro by formation of soluble oligomers.
FEBS letters 2003;542(1-3):147-52.
2003: Zhu Min; Fink Anthony L
Lipid binding inhibits alpha-synuclein fibril formation.
The Journal of biological chemistry 2003;278(19):16873-7.
2003: Uversky Vladimir N; Garriques Liza Nielsen; Millett Ian S; Frokjaer Sven; Brange Jens; Doniach Sebastian; Fink Anthony L
Prediction of the association state of insulin using spectral parameters.
Journal of pharmaceutical sciences 2003;92(4):847-58.
2003: Goers John; Uversky Vladimir N; Fink Anthony L
Polycation-induced oligomerization and accelerated fibrillation of human alpha-synuclein in vitro.
Protein science : a publication of the Protein Society 2003;12(4):702-7.
2003: Munishkina Larissa A; Phelan Cassandra; Uversky Vladimir N; Fink Anthony L
Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes.
Biochemistry 2003;42(9):2720-30.
2003: Denning Daniel P; Patel Samir S; Uversky Vladimir; Fink Anthony L; Rexach Michael
Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2450-5.
2002: Zhu Min; Souillac Pierre O; Ionescu-Zanetti Cristian; Carter Sue A; Fink Anthony L
Surface-catalyzed amyloid fibril formation.
The Journal of biological chemistry 2002;277(52):50914-22.
2002: Li Jie; Uversky Vladimir N; Fink Anthony L
Conformational behavior of human alpha-synuclein is modulated by familial Parkinson's disease point mutations A30P and A53T.
Neurotoxicology 2002;23(4-5):553-67.
2002: Uversky Vladimir N; Li Jie; Bower Kiowa; Fink Anthony L
Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease.
Neurotoxicology 2002;23(4-5):527-36.
2002: Goers John; Permyakov Sergei E; Permyakov Eugene A; Uversky Vladimir N; Fink Anthony L
Conformational prerequisites for alpha-lactalbumin fibrillation.
Biochemistry 2002;41(41):12546-51.
2002: Denning Daniel P; Uversky Vladimir; Patel Samir S; Fink Anthony L; Rexach Michael
The Saccharomyces cerevisiae nucleoporin Nup2p is a natively unfolded protein.
The Journal of biological chemistry 2002;277(36):33447-55.
2002: Abramov Vyacheslav M; Vasiliev Anatoly M; Khlebnikov Valentin S; Vasilenko Raisa N; Kulikova Nataly L; Kosarev Igor V; Ishchenko Alexander T; Gillespie Joel R; Millett Ian S; Fink Anthony L; Uversky Vladimir N
Structural and functional properties of Yersinia pestis Caf1 capsular antigen and their possible role in fulminant development of primary pneumonic plague.
Journal of proteome research 2002;1(4):307-15.
2002: Uversky Vladimir N; Fink Anthony L
Amino acid determinants of alpha-synuclein aggregation: putting together pieces of the puzzle.
FEBS letters 2002;522(1-3):9-13.
2002: Uversky Vladimir N; Yamin Ghiam; Souillac Pierre O; Goers John; Glaser Charles B; Fink Anthony L
Methionine oxidation inhibits fibrillation of human alpha-synuclein in vitro.
FEBS letters 2002;517(1-3):239-44.
2002: Kuznetsova Irina M; Stepanenko Olga V; Turoverov Konstantin K; Zhu Li; Zhou Jun Mei; Fink Anthony L; Uversky Vladimir N
Unraveling multistate unfolding of rabbit muscle creatine kinase.
Biochimica et biophysica acta 2002;1596(1):138-55.
2002: Souillac Pierre O; Uversky Vladimir N; Millett Ian S; Khurana Ritu; Doniach Sebastian; Fink Anthony L
Effect of association state and conformational stability on the kinetics of immunoglobulin light chain amyloid fibril formation at physiological pH.
The Journal of biological chemistry 2002;277(15):12657-65.
2002: Souillac Pierre O; Uversky Vladimir N; Millett Ian S; Khurana Ritu; Doniach Sebastian; Fink Anthony L
Elucidation of the molecular mechanism during the early events in immunoglobulin light chain amyloid fibrillation. Evidence for an off-pathway oligomer at acidic pH.
The Journal of biological chemistry 2002;277(15):12666-79.
2002: Uversky Vladimir N; Li Jie; Souillac Pierre; Millett Ian S; Doniach Sebastian; Jakes Ross; Goedert Michel; Fink Anthony L
Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins.
The Journal of biological chemistry 2002;277(14):11970-8.
2002: Uversky Vladimir N; Permyakov Sergey E; Zagranichny Vasily E; Rodionov Igor L; Fink Anthony L; Cherskaya Alexandra M; Wasserman Lyubov A; Permyakov Eugene A
Effect of zinc and temperature on the conformation of the gamma subunit of retinal phosphodiesterase: a natively unfolded protein.
Journal of proteome research 2002;1(2):149-59.
2002: Uversky Vladimir N; M Cooper Elisa; Bower Kiowa S; Li Jie; Fink Anthony L
Accelerated alpha-synuclein fibrillation in crowded milieu.
FEBS letters 2002;515(1-3):99-103.
2002: Uversky Vladimir N; Fink Anthony L
The chicken-egg scenario of protein folding revisited.
FEBS letters 2002;515(1-3):79-83.
2002: Cohlberg Jeffrey A; Li Jie; Uversky Vladimir N; Fink Anthony L
Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.
Biochemistry 2002;41(5):1502-11.
2002: Manning-Bog Amy B; McCormack Alison L; Li Jie; Uversky Vladimir N; Fink Anthony L; Di Monte Donato A
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein.
The Journal of biological chemistry 2002;277(3):1641-4.
2001: Uversky V N; Li J; Fink A L
Trimethylamine-N-oxide-induced folding of alpha-synuclein.
FEBS letters 2001;509(1):31-5.
2001: Uversky V N; Lee H J; Li J; Fink A L; Lee S J
Stabilization of partially folded conformation during alpha-synuclein oligomerization in both purified and cytosolic preparations.
The Journal of biological chemistry 2001;276(47):43495-8.
2001: Uversky V N; Li J; Fink A L
Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure.
The Journal of biological chemistry 2001;276(47):44284-96.
2001: Li J; Uversky V N; Fink A L
Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human alpha-synuclein.
Biochemistry 2001;40(38):11604-13.
2001: Uversky V N; Li J; Fink A L
Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease.
FEBS letters 2001;500(3):105-8.
2001: Nielsen L; Frokjaer S; Brange J; Uversky V N; Fink A L
Probing the mechanism of insulin fibril formation with insulin mutants.
Biochemistry 2001;40(28):8397-409.
2001: Khurana R; Uversky V N; Nielsen L; Fink A L
Is Congo red an amyloid-specific dye?
The Journal of biological chemistry 2001;276(25):22715-21.
2001: Abramov V M; Vasiliev A M; Vasilenko R N; Kulikova N L; Kosarev I V; Khlebnikov V S; Ishchenko A T; MacIntyre S; Gillespie J R; Khurana R; Korpela T; Fink A L; Uversky V N
Structural and functional similarity between Yersinia pestis capsular protein Caf1 and human interleukin-1 beta.
Biochemistry 2001;40(20):6076-84.
2001: Nielsen L; Khurana R; Coats A; Frokjaer S; Brange J; Vyas S; Uversky V N; Fink A L
Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism.
Biochemistry 2001;40(20):6036-46.
2001: Uversky V N; Li J; Fink A L
Evidence for a partially folded intermediate in alpha-synuclein fibril formation.
The Journal of biological chemistry 2001;276(14):10737-44.
2001: Khurana R; Gillespie J R; Talapatra A; Minert L J; Ionescu-Zanetti C; Millett I; Fink A L
Partially folded intermediates as critical precursors of light chain amyloid fibrils and amorphous aggregates.
Biochemistry 2001;40(12):3525-35.
2001: Nishimura C; Uversky V N; Fink A L
Effect of salts on the stability and folding of staphylococcal nuclease.
Biochemistry 2001;40(7):2113-28.
2000: Uversky V N; Gillespie J R; Fink A L
Why are "natively unfolded" proteins unstructured under physiologic conditions?
Proteins 2000;41(3):415-27.
2000: Fezoui Y; Hartley D M; Harper J D; Khurana R; Walsh D M; Condron M M; Selkoe D J; Lansbury P T; Fink A L; Teplow D B
An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2000;7(3):166-78.
2000: Frate M C; Lietz E J; Santos J; Rossi J P; Fink A L; Ermácora M R
Export and folding of signal-sequenceless Bacillus licheniformis beta-lactamase in Escherichia coli.
European journal of biochemistry / FEBS 2000;267(12):3836-47.
2000: Nishimura C; Riley R; Eastman P; Fink A L
Fluorescence energy transfer indicates similar transient and equilibrium intermediates in staphylococcal nuclease folding.
Journal of molecular biology 2000;299(4):1133-46.
2000: Hokenson M J; Cope G A; Lewis E R; Oberg K A; Fink A L
Enzyme-induced strain/distortion in the ground-state ES complex in beta-lactamase catalysis revealed by FTIR.
Biochemistry 2000;39(21):6538-45.
2000: Lietz E J; Truher H; Kahn D; Hokenson M J; Fink A L
Lysine-73 is involved in the acylation and deacylation of beta-lactamase.
Biochemistry 2000;39(17):4971-81.
2000: Khurana R; Fink A L
Do parallel beta-helix proteins have a unique fourier transform infrared spectrum?
Biophysical journal 2000;78(2):994-1000.
2000: Uversky V N; Gillespie J R; Millett I S; Khodyakova A V; Vasilenko R N; Vasiliev A M; Rodionov I L; Kozlovskaya G D; Dolgikh D A; Fink A L; Doniach S; Permyakov E A; Abramov V M
Zn(2+)-mediated structure formation and compaction of the "natively unfolded" human prothymosin alpha.
Biochemical and biophysical research communications 2000;267(2):663-8.
1999: Segel D J; Eliezer D; Uversky V; Fink A L; Hodgson K O; Doniach S
Transient dimer in the refolding kinetics of cytochrome c characterized by small-angle X-ray scattering.
Biochemistry 1999;38(46):15352-9.
1999: Ionescu-Zanetti C; Khurana R; Gillespie J R; Petrick J S; Trabachino L C; Minert L J; Carter S A; Fink A L
Monitoring the assembly of Ig light-chain amyloid fibrils by atomic force microscopy.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13175-9.
1999: Uversky V N; Gillespie J R; Millett I S; Khodyakova A V; Vasiliev A M; Chernovskaya T V; Vasilenko R N; Kozlovskaya G D; Dolgikh D A; Fink A L; Doniach S; Abramov V M
Natively unfolded human prothymosin alpha adopts partially folded collapsed conformation at acidic pH.
Biochemistry 1999;38(45):15009-16.
1999: Fink A L
Chaperone-mediated protein folding.
Physiological reviews 1999;79(2):425-49.
1999: Uversky V N; Karnoup A S; Khurana R; Segel D J; Doniach S; Fink A L
Association of partially-folded intermediates of staphylococcal nuclease induces structure and stability.
Protein science : a publication of the Protein Society 1999;8(1):161-73.
1999: Seshadri S; Khurana R; Fink A L
Fourier transform infrared spectroscopy in analysis of protein deposits.
Methods in enzymology 1999;309():559-76.
1998: Chirico W J; Markey M L; Fink A L
Conformational changes of an Hsp70 molecular chaperone induced by nucleotides, polypeptides, and N-ethylmaleimide.
Biochemistry 1998;37(39):13862-70.
1998: Segel D J; Fink A L; Hodgson K O; Doniach S
Protein denaturation: a small-angle X-ray scattering study of the ensemble of unfolded states of cytochrome c.
Biochemistry 1998;37(36):12443-51.
1998: Uversky V N; Karnoup A S; Segel D J; Seshadri S; Doniach S; Fink A L
Anion-induced folding of Staphylococcal nuclease: characterization of multiple equilibrium partially folded intermediates.
Journal of molecular biology 1998;278(4):879-94.
1998: Uversky V N; Segel D J; Doniach S; Fink A L
Association-induced folding of globular proteins.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5480-3.
1998: Uversky V N; Fink A L
Structural properties of staphylococcal nuclease in oligomeric A-forms.
Biochemistry. Biokhimii?a 1998;63(4):463-9.
1998: Uversky V N; Fink A L
Structural effect of association on protein molecules in partially folded intermediates.
Biochemistry. Biokhimii?a 1998;63(4):456-62.
1998: Chen E; Wood M J; Fink A L; Kliger D S
Time-resolved circular dichroism studies of protein folding intermediates of cytochrome c.
Biochemistry 1998;37(16):5589-98.
1998: Oberg K A; Fink A L
A new attenuated total reflectance Fourier transform infrared spectroscopy method for the study of proteins in solution.
Analytical biochemistry 1998;256(1):92-106.
1998: Fink A L; Oberg K A; Seshadri S
Discrete intermediates versus molten globule models for protein folding: characterization of partially folded intermediates of apomyoglobin.
Folding & design 1998;3(1):19-25.
1998: Fink A L
Protein aggregation: folding aggregates, inclusion bodies and amyloid.
Folding & design 1998;3(1):R9-23.
1997: Veeraraghavan S; Nall B T; Fink A L
Effect of prolyl isomerase on the folding reactions of staphylococcal nuclease.
Biochemistry 1997;36(49):15134-9.
1997: Hardt K; Joris B; Lepage S; Brasseur R; Lampen J O; Frère J M; Fink A L; Ghuysen J M
The penicillin sensory transducer, BlaR, involved in the inducibility of beta-lactamase synthesis in Bacillus licheniformis is embedded in the plasma membrane via a four-alpha-helix bundle.
Molecular microbiology 1997;23(5):935-44.
1997: Lewis E R; Winterberg K M; Fink A L
A point mutation leads to altered product specificity in beta-lactamase catalysis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):443-7.
1996: Reid K L; Fink A L
Physical interactions between members of the DnaK chaperone machinery: characterization of the DnaK.GrpE complex.
Cell stress & chaperones 1996;1(2):127-37.
1996: Shi L; Kataoka M; Fink A L
Conformational characterization of DnaK and its complexes by small-angle X-ray scattering.
Biochemistry 1996;35(10):3297-308.
1995: Viadiu H; Osuna J; Fink A L; Soberón X
A new TEM beta-lactamase double mutant with broadened specificity reveals substrate-dependent functional interactions.
The Journal of biological chemistry 1995;270(2):781-7.
1995: Osuna J; Viadiu H; Fink A L; Soberón X
Substitution of Asp for Asn at position 132 in the active site of TEM beta-lactamase. Activity toward different substrates and effects of neighboring residues.
The Journal of biological chemistry 1995;270(2):775-80.
1995: Fink A L
Compact intermediates states in protein folding.
Sub-cellular biochemistry 1995;24():27-53.
1995: Fink A L
Compact intermediate states in protein folding.
Annual review of biophysics and biomolecular structure 1995;24():495-522.
1995: Fink A L
Molten globules.
Methods in molecular biology (Clifton, N.J.) 1995;40():343-60.
1994: Escobar W A; Miller J; Fink A L
Effects of site-specific mutagenesis of tyrosine 105 in a class A beta-lactamase.
The Biochemical journal 1994;303 ( Pt 2)():555-8.
1994: Fink A L; Calciano L J; Goto Y; Kurotsu T; Palleros D R
Classification of acid denaturation of proteins: intermediates and unfolded states.
Biochemistry 1994;33(41):12504-11.
1994: Shi L; Palleros D R; Fink A L
Protein conformational changes induced by 1,1'-bis(4-anilino-5-naphthalenesulfonic acid): preferential binding to the molten globule of DnaK.
Biochemistry 1994;33(24):7536-46.
1994: Escobar W A; Tan A K; Lewis E R; Fink A L
Site-directed mutagenesis of glutamate-166 in beta-lactamase leads to a branched path mechanism.
Biochemistry 1994;33(24):7619-26.
1994: Palleros D R; Shi L; Reid K L; Fink A L
hsp70-protein complexes. Complex stability and conformation of bound substrate protein.
The Journal of biological chemistry 1994;269(18):13107-14.
1994: Oberg K; Chrunyk B A; Wetzel R; Fink A L
Nativelike secondary structure in interleukin-1 beta inclusion bodies by attenuated total reflectance FTIR.
Biochemistry 1994;33(9):2628-34.
1994: Seshadri S; Oberg K A; Fink A L
Thermally denatured ribonuclease A retains secondary structure as shown by FTIR.
Biochemistry 1994;33(6):1351-5.
1994: Goto Y; Fink A L
Acid-induced folding of heme proteins.
Methods in enzymology 1994;232():3-15.
1993: Palleros D R; Reid K L; Shi L; Fink A L
DnaK ATPase activity revisited.
FEBS letters 1993;336(1):124-8.
1993: Palleros D R; Reid K L; Shi L; Welch W J; Fink A L
ATP-induced protein-Hsp70 complex dissociation requires K+ but not ATP hydrolysis.
Nature 1993;365(6447):664-6.
1993: Hamada D; Hoshino M; Kataoka M; Fink A L; Goto Y
Intermediate conformational states of apocytochrome c.
Biochemistry 1993;32(39):10351-8.
1993: Fink A L; Calciano L J; Goto Y; Nishimura M; Swedberg S A
Characterization of the stable, acid-induced, molten globule-like state of staphylococcal nuclease.
Protein science : a publication of the Protein Society 1993;2(7):1155-60.
1993: Calciano L J; Escobar W A; Millhauser G L; Miick S M; Rubaloff J; Todd A P; Fink A L
Side-chain mobility of the beta-lactamase A state probed by electron spin resonance spectroscopy.
Biochemistry 1993;32(21):5644-9.
1993: Hagihara Y; Aimoto S; Fink A L; Goto Y
Guanidine hydrochloride-induced folding of proteins.
Journal of molecular biology 1993;231(2):180-4.
1993: Palleros D R; Shi L; Reid K L; Fink A L
Three-state denaturation of DnaK induced by guanidine hydrochloride. Evidence for an expandable intermediate.
Biochemistry 1993;32(16):4314-21.
1993: De Young L R; Dill K A; Fink A L
Aggregation and denaturation of apomyoglobin in aqueous urea solutions.
Biochemistry 1993;32(15):3877-86.
1993: Nakano T; Antonino L C; Fox R O; Fink A L
Effect of proline mutations on the stability and kinetics of folding of staphylococcal nuclease.
Biochemistry 1993;32(10):2534-41.
1993: Knox J R; Moews P C; Escobar W A; Fink A L
A catalytically-impaired class A beta-lactamase: 2 A crystal structure and kinetics of the Bacillus licheniformis E166A mutant.
Protein engineering 1993;6(1):11-8.
1992: Lustig B; Fink A L
Secondary structure formation precedes tertiary structure in the refolding of ribonuclease A.
Biochimica et biophysica acta 1992;1121(1-2):229-33.
1992: Palleros D R; Reid K L; McCarty J S; Walker G C; Fink A L
DnaK, hsp73, and their molten globules. Two different ways heat shock proteins respond to heat.
The Journal of biological chemistry 1992;267(8):5279-85.
1992: Lustig B; Fink A L
The thermal denaturation of ribonuclease A in aqueous-methanol solvents.
Biochimica et biophysica acta 1992;1119(2):205-10.
1992: Tan A K; Fink A L
Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamase.
The Biochemical journal 1992;281 ( Pt 1)():191-6.
1991: Escobar W A; Tan A K; Fink A L
Site-directed mutagenesis of beta-lactamase leading to accumulation of a catalytic intermediate.
Biochemistry 1991;30(44):10783-7.
1991: Antonino L C; Kautz R A; Nakano T; Fox R O; Fink A L
Cold denaturation and 2H2O stabilization of a staphylococcal nuclease mutant.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7715-8.
1991: Palleros D R; Welch W J; Fink A L
Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of binding.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5719-23.
1990: Goto Y; Fink A L
Phase diagram for acidic conformational states of apomyoglobin.
Journal of molecular biology 1990;214(4):803-5.
1990: Nakano T; Fink A L
The folding of staphylococcal nuclease in the presence of methanol or guanidine thiocyanate.
The Journal of biological chemistry 1990;265(21):12356-62.
1990: Ellerby L M; Escobar W A; Fink A L; Mitchinson C; Wells J A
The role of lysine-234 in beta-lactamase catalysis probed by site-directed mutagenesis.
Biochemistry 1990;29(24):5797-806.
1990: Swedberg S A; Pesek J J; Fink A L
Attenuated total reflectance Fourier transform infrared analysis of an acyl-enzyme intermediate of alpha-chymotrypsin.
Analytical biochemistry 1990;186(1):153-8.
1990: Anderson W D; Fink A L; Perry L J; Wetzel R
Effect of an engineered disulfide bond on the folding of T4 lysozyme at low temperatures.
Biochemistry 1990;29(13):3331-7.
1990: Goto Y; Takahashi N; Fink A L
Mechanism of acid-induced folding of proteins.
Biochemistry 1990;29(14):3480-8.
1990: Goto Y; Calciano L J; Fink A L
Acid-induced folding of proteins.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):573-7.
1990: Virden R; Tan A K; Fink A L
Cryoenzymology of staphylococcal beta-lactamase: trapping a serine-70-linked acyl-enzyme.
Biochemistry 1990;29(1):145-53.
1989: Cartwright S J; Tan A K; Fink A L
Trapping the acyl-enzyme intermediate in beta-lactamase I catalysis.
The Biochemical journal 1989;263(3):905-12.
1989: Goto Y; Fink A L
Conformational states of beta-lactamase: molten-globule states at acidic and alkaline pH with high salt.
Biochemistry 1989;28(3):945-52.
1989: Rizwi I; Tan A K; Fink A L; Virden R
Clavulanate inactivation of Staphylococcus aureus beta-lactamase.
The Biochemical journal 1989;258(1):205-9.
1988: Fink A L; Anderson W D; Hattersley J E; Lustig B S
The effect of methanol and temperature on the kinetics of refolding of ribonuclease A.
FEBS letters 1988;236(1):190-4.
1988: Fink A L; Anderson W D; Antonino L
Trapping the fast-refolding state of ribonuclease A at subzero temperatures.
FEBS letters 1988;229(1):123-6.
1988: Biringer R G; Fink A L
Intermediates in the refolding of ribonuclease at subzero temperatures. 3. Multiple folding pathways.
Biochemistry 1988;27(1):315-25.
1988: Biringer R G; Fink A L
Intermediates in the refolding of ribonuclease at subzero temperatures. 1. Monitoring by nitrotyrosine absorbance.
Biochemistry 1988;27(1):301-11.
1988: Biringer R G; Austin C M; Fink A L
Intermediates in the refolding of ribonuclease at subzero temperatures. 2. Monitoring by inhibitor binding and catalytic activity.
Biochemistry 1988;27(1):311-5.
1988: Berry S C; Fink A L; Shenvi A B; Kettner C A
Interaction of peptide boronic acids with elastase: circular dichroism studies.
Proteins 1988;4(3):205-10.
1987: Fink A L; Kar D; Kotin R
Ribonuclease structure and catalysis: effects of crystalline enzyme, alcohol cryosolvents, low temperatures, and product inhibition.
Biochemistry 1987;26(26):8571-9.
1987: Koerber S C; Fink A L
The analysis of enzyme progress curves by numerical differentiation, including competitive product inhibition and enzyme reactivation.
Analytical biochemistry 1987;165(1):75-87.
1987: Coll R J; Fink A L
Cryoenzymology of human plasmin catalysis: comparison of cryosolvents and reactions with nitrophenyl ester and anilide substrates.
Cryobiology 1987;24(4):332-44.
1987: Fink A L; Behner K M; Tan A K
Kinetic and structural characterization of reversibly inactivated beta-lactamase.
Biochemistry 1987;26(14):4248-58.
1987: Fink A L; Painter B
Characterization of the unfolding of ribonuclease A in aqueous methanol solvents.
Biochemistry 1987;26(6):1665-71.
1986: Fink A L
Effects of cryoprotectants on enzyme structure.
Cryobiology 1986;23(1):28-37.
1986: Compton P D; Coll R J; Fink A L
Effects of methanol cryosolvents on the structural and catalytic properties of bovine trypsin.
The Journal of biological chemistry 1986;261(3):1248-52.
1986: Fink A L
Protein folding in cryosolvents and at subzero temperatures.
Methods in enzymology 1986;131():173-85.
1984: Dunn B M; Fink A L
Cryoenzymology of porcine pepsin.
Biochemistry 1984;23(22):5241-7.
1984: Hofmann T; Fink A L; Dunn B M
Cryoenzymology of penicillopepsin; with an appendix: mechanism of action of aspartyl proteinases.
Biochemistry 1984;23(22):5247-56.
1984: Compton P D; Fink A L
Low-temperature reactions of trypsin with p-nitroanilide substrates: tetrahedral intermediate formation or enzyme isomerization.
Biochemistry 1984;23(13):2989-94.
1983: Geeves M A; Koerber S C; Dunn M F; Fink A L
The effect of cryosolvents on the spectral and catalytic properties of liver alcohol dehydrogenase.
The Journal of biological chemistry 1983;258(20):12184-9.
1982: Biringer R G; Fink A L
Methanol-stabilized intermediates in the thermal unfolding of ribonuclease A. Characterization by 1H nuclear magnetic resonance.
Journal of molecular biology 1982;160(1):87-116.
1982: Biringer R G; Fink A L
Observation of intermediates in the folding of ribonuclease A at low temperature using proton nuclear magnetic resonance.
Biochemistry 1982;21(19):4748-55.
1982: Cartwright S J; Fink A L
Isolation of a covalent intermediate in beta -lactamase I catalysis.
FEBS letters 1982;137(2):186-8.
1982: Coll R J; Compton P D; Fink A L
Preparation and properties of covalent compounds and intermediates of serine proteases.
Methods in enzymology 1982;87():66-76.
1981: Fink A L; Cartwright S J
Cryoenzymology.
CRC critical reviews in biochemistry 1981;11(2):145-207.
1981: Fink A L; Petsko G A
X-ray cryoenzymology.
Advances in enzymology and related areas of molecular biology 1981;52():177-246.
1980: Weber J P; Fink A L
Temperature-dependent change in the rate-limiting step of beta-glucosidase catalysis.
The Journal of biological chemistry 1980;255(19):9030-2.
1980: Greeves M A; Fink A L
The binding of NADH to horse liver alcohol dehydrogenase at subzero temperatures. A three-step reaction.
The Journal of biological chemistry 1980;255(8):3248-50.
1980: Compton P; Fink A L
The detection, accumulation and stabilization of a tetrahedral intermediate in trypsin catalysis.
Biochemical and biophysical research communications 1980;93(2):427-31.
1980: Fink A L; Homer R; Weber J P
Resolution of the individual steps in the reaction of lysozyme with the trimer and hexamer of N-acetyl-D-glucosamine at subzero temperatures.
Biochemistry 1980;19(4):811-20.

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