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Stephen Fink

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Liqun Yu; Martin C Frith; Yutaka Suzuki; Robert A Peterfreund; Tom Gearan; Sumio Sugano; Michael A Schwarzschild; Zhiping Weng; J Stephen Fink; Jiang-Fan Chen
Characterization of genomic organization of the adenosine A2A receptor gene by molecular and bioinformatics analyses.
J Stephen Fink; Anti Kalda; Hoon Ryu; Edward C Stack; Michael A Schwarzschild; Jiang-Fan Chen; Robert J Ferrante
Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage.
Yoshihiro Urade; Naomi Eguchi; Wei-Min Qu; Mie Sakata; Zhi-Li Huang; Jiang-Fan Chen; Michael A Schwarzschild; J Stephen Fink; Osamu Hayaishi
Sleep regulation in adenosine A2A receptor-deficient mice.

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All Publications

2004: Liqun Yu; Martin C Frith; Yutaka Suzuki; Robert A Peterfreund; Tom Gearan; Sumio Sugano; Michael A Schwarzschild; Zhiping Weng; J Stephen Fink; Jiang-Fan Chen
Characterization of genomic organization of the adenosine A2A receptor gene by molecular and bioinformatics analyses.
Brain research 2004;1000(1-2):156-73.
2004: J Stephen Fink; Anti Kalda; Hoon Ryu; Edward C Stack; Michael A Schwarzschild; Jiang-Fan Chen; Robert J Ferrante
Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage.
Journal of neurochemistry 2004;88(3):538-44.
2003: Yoshihiro Urade; Naomi Eguchi; Wei-Min Qu; Mie Sakata; Zhi-Li Huang; Jiang-Fan Chen; Michael A Schwarzschild; J Stephen Fink; Osamu Hayaishi
Sleep regulation in adenosine A2A receptor-deficient mice.
Neurology 2003;61(11 Suppl 6):S94-6.
2003: Yuan-Ji Day; Liping Huang; Marcia McDuffie; Diane L Rosin; Hong Ye; Jiang-Fan Chen; Michael A Schwarzschild; J Stephen Fink; Joel Linden; Mark D Okusa
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells.
The Journal of clinical investigation 2003;112(6):883-91.
2003: M Carmen Montesinos; Avani Desai; David L Delano; Jiang-Fan Chen; J Stephen Fink; Marlene A Jacobson; Bruce N Cronstein
Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68.
Arthritis and rheumatism 2003;48(1):240-7.
2002: S Joseph Leibovich; Jiang-Fan Chen; Grace Pinhal-Enfield; Paula C Belem; Genie Elson; Anthony Rosania; Madhuri Ramanathan; Carmen Montesinos; Marlene Jacobson; Michael A Schwarzschild; J Stephen Fink; Bruce N Cronstein
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
The American journal of pathology 2002;160(6):2231-44.
2002: M Carmen Montesinos; Avani Desai; Jiang-Fan Chen; Herman Yee; Michael A Schwarzschild; J Stephen Fink; Bruce N Cronstein
Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors.
The American journal of pathology 2002;160(6):2009-18.
2001: Jiang-Fan Chen; Rosario Moratalla; Francesco Impagnatiello; David K Grandy; Beatriz Cuellar; M Rubinstein; MA Beilstein; E Hackett; J Stephen Fink; Malcolm J Low; Ennio Ongini; Michael A Schwarzschild
The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1970-5.
2000: Sergey Apasov; Jiang-Fan Chen; Patrick T Smith; Michael A Schwarzschild; J Stephen Fink; Michail V Sitkovsky
Study of A(2A) adenosine receptor gene deficient mice reveals that adenosine analogue CGS 21680 possesses no A(2A) receptor-unrelated lymphotoxicity.
British journal of pharmacology 2000;131(1):43-50.
2000: Jiang-Fan Chen; MA Beilstein; Yue-Hang Xu; T J Turner; Rosario Moratalla; David G Standaert; V J Aloyo; J Stephen Fink; Michael A Schwarzschild
Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A(2A) adenosine receptors.
Neuroscience 2000;97(1):195-204.
1999: Jiang-Fan Chen; Z Huang; J Ma; J Zhu; Rosario Moratalla; David G Standaert; Michael A Moskowitz; J Stephen Fink; Michael A Schwarzschild
A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(21):9192-200.
1998: P Rajan; Tom Gearan; J Stephen Fink
Leukemia inhibitory factor and NGF regulate signal transducers and activators of transcription activation in sympathetic ganglia: convergence of cytokine- and neurotrophin-signaling pathways.
Brain research 1998;802(1-2):198-204.
1998: AJ Symes; Tom Gearan; J Stephen Fink
NFAT interactions with the vasoactive intestinal peptide cytokine response element.
Journal of neuroscience research 1998;52(1):93-104.
1998: T Servidei; Y Aoki; S E Lewis; AJ Symes; J Stephen Fink; Steven A Reeves
Coordinate regulation of STAT signaling and c-fos expression by the tyrosine phosphatase SHP-2.
The Journal of biological chemistry 1998;273(11):6233-41.
1997: Beth A Habecker; AJ Symes; Neil stahl; Nicole Francis; Aris N Economides; J Stephen Fink; George D Yancopoulos; Story C Landis
A sweat gland-derived differentiation activity acts through known cytokine signaling pathways.
The Journal of biological chemistry 1997;272(48):30421-8.
1997: Robert A Peterfreund; EK Gies; J Stephen Fink
Protein kinase C regulates adenosine A2a receptor mRNA expression in SH-SY5Y cells.
European journal of pharmacology 1997;336(1):71-80.
1997: AJ Symes; Neil stahl; Steven A Reeves; TJ Farruggella; T Servidei; Tom Gearan; George D Yancopoulos; J Stephen Fink
The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression.
Current biology : CB 1997;7(9):697-700.
1997: A E Pollack; S M Turgeon; J Stephen Fink
Apomorphine priming alters the response of striatal outflow pathways to D2 agonist stimulation in 6-hydroxydopamine-lesioned rats.
Neuroscience 1997;79(1):79-93.
1997: AJ Symes; Tom Gearan; J Eby; J Stephen Fink
Integration of Jak-Stat and AP-1 signaling pathways at the vasoactive intestinal peptide cytokine response element regulates ciliary neurotrophic factor-dependent transcription.
The Journal of biological chemistry 1997;272(15):9648-54.
1997: S M Turgeon; A E Pollack; J Stephen Fink
Enhanced CREB phosphorylation and changes in c-Fos and FRA expression in striatum accompany amphetamine sensitization.
Brain research 1997;749(1):120-6.
1996: A E Pollack; J Stephen Fink
Synergistic interaction between an adenosine antagonist and a D1 dopamine agonist on rotational behavior and striatal c-Fos induction in 6-hydroxydopamine-lesioned rats.
Brain research 1996;743(1-2):124-30.
1996: L M Tsuruda; E D Lamperti; S E Lewis; P J Tolentino; Pieter Dikkes; L Villa-Komaroff; K M Ebert; J Stephen Fink
Region-specific central nervous system expression and axotomy-induced regulation in sympathetic neurons of a VIP-beta-galactosidase fusion gene in transgenic mice.
Brain research. Molecular brain research 1996;42(2):181-92.
1996: P Rajan; AJ Symes; J Stephen Fink
STAT proteins are activated by ciliary neurotrophic factor in cells of central nervous system origin.
Journal of neuroscience research 1996;43(4):403-11.
1996: S M Turgeon; A E Pollack; L Schusheim; J Stephen Fink
Effects of selective adenosine A1 and A2a agonists on amphetamine-induced locomotion and c-Fos in striatum and nucleus accumbens.
Brain research 1996;707(1):75-80.
1996: Robert A Peterfreund; Mia MacCollin; James Gusella; J Stephen Fink
Characterization and expression of the human A2a adenosine receptor gene.
Journal of neurochemistry 1996;66(1):362-8.
1995: Robert A Peterfreund; B E Kosofsky; J Stephen Fink
Cellular localization of dopamine D2 receptor messenger RNA in the rat trigeminal ganglion.
Anesthesia and analgesia 1995;81(6):1181-5.
1995: P Rajan; C L Stewart; J Stephen Fink
LIF-mediated activation of STAT proteins after neuronal injury in vivo.
Neuroreport 1995;6(16):2240-4.
1995: AJ Symes; L Corpus; J Stephen Fink
Differences in nuclear signaling by leukemia inhibitory factor and interferon-gamma: the role of STAT proteins in regulating vasoactive intestinal peptide gene expression.
Journal of neurochemistry 1995;65(5):1926-33.
1995: P J Tolentino; Pieter Dikkes; L Tsuruda; K Ebert; J Stephen Fink; L Villa-Komaroff; E D Lamperti
Quantitative analysis of the expression of a VIP transgene.
Brain research. Molecular brain research 1995;33(1):47-60.
1995: A E Pollack; J Stephen Fink
Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway.
Neuroscience 1995;68(3):721-8.
1995: AJ Symes; P Rajan; L Corpus; J Stephen Fink
C/EBP-related sites in addition to a STAT site are necessary for ciliary neurotrophic factor-leukemia inhibitory factor-dependent transcriptional activation by the vasoactive intestinal peptide cytokine response element.
The Journal of biological chemistry 1995;270(14):8068-75.
1994: AJ Symes; S Lewis; L Corpus; P Rajan; Steven E Hyman; J Stephen Fink
STAT proteins participate in the regulation of the vasoactive intestinal peptide gene by the ciliary neurotrophic factor family of cytokines.
Molecular endocrinology (Baltimore, Md.) 1994;8(12):1750-63.
1994: Michael A Schwarzschild; William T Dauer; S E Lewis; L K Hamill; J Stephen Fink; Steven E Hyman
Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures.
Journal of neurochemistry 1994;63(4):1246-54.
1994: S E Lewis; Mahendra S Rao; AJ Symes; William T Dauer; J Stephen Fink; Story C Landis; Steven E Hyman
Coordinate regulation of choline acetyltransferase, tyrosine hydroxylase, and neuropeptide mRNAs by ciliary neurotrophic factor and leukemia inhibitory factor in cultured sympathetic neurons.
Journal of neurochemistry 1994;63(2):429-38.
1994: Mia MacCollin; Robert A Peterfreund; Marcy E MacDonald; J Stephen Fink; James Gusella
Mapping of a human A2a adenosine receptor (ADORA2) to chromosome 22.
Genomics 1994;20(2):332-3.
1994: Heinz Baumann; AJ Symes; M R Comeau; K K Morella; Y Wang; D Friend; Steven F Ziegler; J Stephen Fink; D P Gearing
Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells.
Molecular and cellular biology 1994;14(1):138-46.
1993: A E Pollack; Madaline B Harrison; G Frederick Wooten; J Stephen Fink
Differential localization of A2a adenosine receptor mRNA with D1 and D2 dopamine receptor mRNA in striatal output pathways following a selective lesion of striatonigral neurons.
Brain research 1993;631(1):161-6.
1993: Joel Linden; H E Taylor; A S Robeva; A L Tucker; J H Stehle; S A Rivkees; J Stephen Fink; Steven M Reppert
Molecular cloning and functional expression of a sheep A3 adenosine receptor with widespread tissue distribution.
Molecular pharmacology 1993;44(3):524-32.
1993: E M Adler; J Stephen Fink
Calcium regulation of vasoactive intestinal polypeptide mRNA abundance in SH-SY5Y human neuroblastoma cells.
Journal of neurochemistry 1993;61(2):727-37.
1993: AJ Symes; Mahendra S Rao; S E Lewis; Story C Landis; Steven E Hyman; J Stephen Fink
Ciliary neurotrophic factor coordinately activates transcription of neuropeptide genes in a neuroblastoma cell line.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):572-6.
1992: Mahendra S Rao; AJ Symes; N Malik; M Shoyab; J Stephen Fink; Story C Landis
Oncostatin M regulates VIP expression in a human neuroblastoma cell line.
Neuroreport 1992;3(10):865-8.
1992: J Stephen Fink; David R Weaver; S A Rivkees; Robert A Peterfreund; A E Pollack; E M Adler; S M Reppert
Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum.
Brain research. Molecular brain research 1992;14(3):186-95.
1991: J L Meinkoth; M R Montminy; J Stephen Fink; J R Feramisco
Induction of a cyclic AMP-responsive gene in living cells requires the nuclear factor CREB.
Molecular and cellular biology 1991;11(3):1759-64.
1991: J Stephen Fink; M Verhave; K Walton; Gail Mandel; Richard H Goodman
Cyclic AMP- and phorbol ester-induced transcriptional activation are mediated by the same enhancer element in the human vasoactive intestinal peptide gene.
The Journal of biological chemistry 1991;266(6):3882-7.
1988: J Stephen Fink; M Verhave; S Kasper; T Tsukada; Gail Mandel; Richard H Goodman
The CGTCA sequence motif is essential for biological activity of the vasoactive intestinal peptide gene cAMP-regulated enhancer.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(18):6662-6.
1987: T Tsukada; J Stephen Fink; Gail Mandel; Richard H Goodman
Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.
The Journal of biological chemistry 1987;262(18):8743-7.
1987: Richard H Goodman; Andrew B Leiter; Malcolm J Low; M R Montminy; T Tsukada; J Stephen Fink; Gail Mandel
Biosynthesis of pancreatic islet hormones.
Hepatology (Baltimore, Md.) 1987;7(1 Suppl):36S-41S.