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Ludger Fink

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Katja Hattar; Dagmar S Lang; Rajkumar Savai; Ralph Theo Schermuly; Anja Schmall; Werner Seeger; Ulf Sibelius; Florentine S B Subtil; Ekkehard Vollmer; Jochen Wilhelm; Gamal-Andre Banat; Gabriele Dahlem; Bastian Eul; Ludger Fink; Torsten Goldmann; Friedrich Grimminger; Ulrich Grandel
Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation.
Sibel Avcuoglu; Ludger Fink; Andreas Günther; Leigh M Marsh; Rory Morty; Werner Seeger; Norbert Weissmann; Malgorzata Wygrecka; Grazyna Kwapiszewska
Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.
Martina Korfei; Günter Lochnit; Benjamin Loeh; Poornima Mahavadi; Philipp Markart; Klaus T Preissner; Clemens Ruppert; Liliana Schaefer; Sigrid Schmitt; Werner Seeger; Malgorzata Wygrecka; Philippe Bonniaud; Ludger Fink; Ingrid Henneke; Walter Klepetko; Andreas Guenther
Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs.

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All Publications

2013: Katja Hattar; Dagmar S Lang; Rajkumar Savai; Ralph Theo Schermuly; Anja Schmall; Werner Seeger; Ulf Sibelius; Florentine S B Subtil; Ekkehard Vollmer; Jochen Wilhelm; Gamal-Andre Banat; Gabriele Dahlem; Bastian Eul; Ludger Fink; Torsten Goldmann; Friedrich Grimminger; Ulrich Grandel
Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation.
Cancer immunology, immunotherapy : CII 2013;62(2):309-20.
2011: Sibel Avcuoglu; Ludger Fink; Andreas Günther; Leigh M Marsh; Rory Morty; Werner Seeger; Norbert Weissmann; Malgorzata Wygrecka; Grazyna Kwapiszewska
Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2011;45(4):768-80.
2011: Martina Korfei; Günter Lochnit; Benjamin Loeh; Poornima Mahavadi; Philipp Markart; Klaus T Preissner; Clemens Ruppert; Liliana Schaefer; Sigrid Schmitt; Werner Seeger; Malgorzata Wygrecka; Philippe Bonniaud; Ludger Fink; Ingrid Henneke; Walter Klepetko; Andreas Guenther
Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs.
Journal of proteome research 2011;10(5):2185-205.
2009: Ulrich Grandel; Diana Heygster; Ulf Sibelius; Ludger Fink; Stefanie Sigel; Werner Seeger; Friedrich Grimminger; Katja Hattar
Amplification of lipopolysaccharide-induced cytokine synthesis in non-small cell lung cancer/neutrophil cocultures.
Molecular cancer research : MCR 2009;7(10):1729-35.
2009: Cornelia Fink; Roswitha Weigel; Ludger Fink; Jochen Wilhelm; Sabine Kliesch; Martina Zeiler; Martin Bergmann; Ralph Brehm
Claudin-11 is over-expressed and dislocated from the blood-testis barrier in Sertoli cells associated with testicular intraepithelial neoplasia in men.
Histochemistry and cell biology 2009;131(6):755-64.
2009: Daniel G Sedding; Monique Tröbs; Fabian Reich; Gerhard Walker; Ludger Fink; Werner Haberbosch; Wigbert Rau; Harald Tillmanns; Klaus T Preissner; Rainer M Bohle; Alexander C Langheinrich
3-Deazaadenosine prevents smooth muscle cell proliferation and neointima formation by interfering with Ras signaling.
Circulation research 2009;104(10):1192-200.
2009: Melanie Königshoff; Monika Kramer; Nisha Balsara; Jochen Wilhelm; Oana Veronica Amarie; Andreas Jahn; Frank Rose; Ludger Fink; Werner Seeger; Liliana Schaefer; Andreas Günther; Oliver Eickelberg
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis.
The Journal of clinical investigation 2009;119(4):772-87.
2009: Stephanie Wolff; Sabine Klatt; Jens C Wolff; Jochen Wilhelm; Ludger Fink; Manfred Kaps; Bernhard Rosengarten
Endotoxin-induced gene expression differences in the brain and effects of iNOS inhibition and norepinephrine.
Intensive care medicine 2009;35(4):730-9.
2009: C Dierkes; M Kreisel; A Schulz; Jürgen Steinmeyer; J-C Wolff; Ludger Fink
Catabolic properties of microdissected human endosteal bone lining cells.
Calcified tissue international 2009;84(2):146-55.
2008: Martina Korfei; Clemens Ruppert; Poornima Mahavadi; Ingrid Henneke; Philipp Markart; Miriam Koch; Gyoergy Lang; Ludger Fink; Rainer-Maria Bohle; Werner Seeger; Timothy E Weaver; Andreas Guenther
Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine 2008;178(8):838-46.
2008: Grazyna Kwapiszewska; Malgorzata Wygrecka; Leigh M Marsh; Sigrid Schmitt; Roger Trösser; Jochen Wilhelm; Katja Helmus; Bastian Eul; Anna Zakrzewicz; Hossein A Ghofrani; Ralph Theo Schermuly; Rainer M Bohle; Friedrich Grimminger; Werner Seeger; Oliver Eickelberg; Ludger Fink; Norbert Weissmann
Fhl-1, a new key protein in pulmonary hypertension.
Circulation 2008;118(11):1183-94.
2008: Christina Rüttinger; Martin Bergmann; Ludger Fink; Sandra Pesch; Klaus Seitz; Astrid Trautmann; Klaus Steger; Lutz Konrad; Ralph Brehm
Expression of connexin 43 in normal canine testes and canine testicular tumors.
Histochemistry and cell biology 2008;130(3):537-48.
2007: Melanie Königshoff; Anke Wilhelm; Andreas Jahn; Daniel G Sedding; Oana V Amarie; Bastian Eul; Werner Seeger; Ludger Fink; Andreas Günther; Oliver Eickelberg; Frank Rose
The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis.
American journal of respiratory cell and molecular biology 2007;37(6):640-50.
2007: Malgorzata Wygrecka; Philipp Markart; Ludger Fink; Andreas Guenther; Klaus T Preissner
Raised protein levels and altered cellular expression of factor VII activating protease (FSAP) in the lungs of patients with acute respiratory distress syndrome (ARDS).
Thorax 2007;62(10):880-8.
2007: Manish Mittal; Markus Roth; Peter König; Simone Hofmann; Eva Dony; Parag Goyal; Anne-Christin Selbitz; Ralph Theo Schermuly; Hossein A Ghofrani; Grazyna Kwapiszewska; Wolfgang Kummer; Walter Klepetko; Mir Ali Reza Hoda; Ludger Fink; Jörg Hänze; Werner Seeger; Friedrich Grimminger; Harald Schmidt; Norbert Weissmann
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.
Circulation research 2007;101(3):258-67.
2006: Beate Berghöfer; Ture Frommer; Gabriela Haley; Ludger Fink; Gregor Bein; Holger Hackstein
TLR7 ligands induce higher IFN-alpha production in females.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2088-96.
2006: Jochen Wilhelm; Jai Prakash Muyal; Johannes Best; Grazyna Kwapiszewska; Maria Magdalena Stein; Werner Seeger; Rainer M Bohle; Ludger Fink
Systematic comparison of the T7-IVT and SMART-based RNA preamplification techniques for DNA microarray experiments.
Clinical chemistry 2006;52(6):1161-7.
2006: Ludger Fink; Grazyna Kwapiszewska; Jochen Wilhelm; Rainer M Bohle
Laser-microdissection for cell type- and compartment-specific analyses on genomic and proteomic level.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2006;57 Suppl 2():25-9.
2006: Norbert Weissmann; Stefanie Zeller; Rolf Schäfer; Carmen Turowski; Mahmut Ay; Karin Quanz; Hossein A Ghofrani; Ralph Theo Schermuly; Ludger Fink; Werner Seeger; Friedrich Grimminger
Impact of mitochondria and NADPH oxidases on acute and sustained hypoxic pulmonary vasoconstriction.
American journal of respiratory cell and molecular biology 2006;34(4):505-13.
2006: Katja Hattar; Ulrich Grandel; Alexander Moeller; Ludger Fink; Julia Iglhaut; Thomas Hartung; Siegfried Morath; Werner Seeger; Friedrich Grimminger; Ulf Sibelius
Lipoteichoic acid (LTA) from Staphylococcus aureus stimulates human neutrophil cytokine release by a CD14-dependent, Toll-like-receptor-independent mechanism: Autocrine role of tumor necrosis factor-[alpha] in mediating LTA-induced interleukin-8 generation.
Critical care medicine 2006;34(3):835-41.
2005: Norbert Weissmann; Daniel Manz; Daniela Buchspies; Stephan Keller; Tanja Mehling; Robert Voswinckel; Karin Quanz; Hossein A Ghofrani; Ralph Theo Schermuly; Ludger Fink; Werner Seeger; Max Gassmann; Friedrich Grimminger
Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia.
Thrombosis and haemostasis 2005;94(3):630-8.
2005: Ulrich Grandel; Michael Hopf; Michael Buerke; Katja Hattar; Martina Heep; Ludger Fink; Rainer M Bohle; Siegfried Morath; Thomas Hartung; Soni Pullamsetti; Ralph Theo Schermuly; Werner Seeger; Friedrich Grimminger; Ulf Sibelius
Mechanisms of cardiac depression caused by lipoteichoic acids from Staphylococcus aureus in isolated rat hearts.
Circulation 2005;112(5):691-8.
2005: Sonja Blöcher; Ludger Fink; Rainer M Bohle; Martin Bergmann; Klaus Steger
CREM activator and repressor isoform expression in human male germ cells.
International journal of andrology 2005;28(4):215-23.
2005: manjita srivastava; Steffen Jung; Jochen Wilhelm; Ludger Fink; Frank Bühling; Tobias Welte; Rainer M Bohle; Werner Seeger; Jürgen Lohmeyer; Ulrich A Maus
The inflammatory versus constitutive trafficking of mononuclear phagocytes into the alveolar space of mice is associated with drastic changes in their gene expression profiles.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1884-93.
2005: Soni Pullamsetti; Ladislau Kiss; Hossein A Ghofrani; Robert Voswinckel; Peter Haredza; Walter Klepetko; Clemens Aigner; Ludger Fink; Jai Prakash Muyal; Norbert Weissmann; Friedrich Grimminger; Werner Seeger; Ralph Theo Schermuly
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1175-7.
2005: Grazyna Kwapiszewska; Jochen Wilhelm; Stephanie Wolff; Isabel Laumanns; Inke R Koenig; Andreas Ziegler; Werner Seeger; Rainer M Bohle; Norbert Weissmann; Ludger Fink
Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension.
Respiratory research 2005;6():109.
2005: Ludger Fink; Rainer M Bohle
Laser microdissection and RNA analysis.
Methods in molecular biology (Clifton, N.J.) 2005;293():167-85.
2004: Grazyna Kwapiszewska; Markus Meyer; Ralf Bogumil; Rainer M Bohle; Werner Seeger; Norbert Weissmann; Ludger Fink
Identification of proteins in laser-microdissected small cell numbers by SELDI-TOF and Tandem MS.
BMC biotechnology 2004;4():30.
2004: Malgorzata Wygrecka; Philipp Markart; Clemens Ruppert; Tim Kuchenbuch; Ludger Fink; Rainer M Bohle; Friedrich Grimminger; Werner Seeger; Andreas Günther
Compartment- and cell-specific expression of coagulation and fibrinolysis factors in the murine lung undergoing inhalational versus intravenous endotoxin application.
Thrombosis and haemostasis 2004;92(3):529-40.
2004: Parag Goyal; Norbert Weissmann; Friedrich Grimminger; Cornelia Hegel; Lucius Bader; Frank Rose; Ludger Fink; Hossein A Ghofrani; Ralph Theo Schermuly; Harald Schmidt; Werner Seeger; Jörg Hänze
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species.
Free radical biology & medicine 2004;36(10):1279-88.
2004: Norbert Weissmann; Henrik Vogels; Ralph Theo Schermuly; Hossein A Ghofrani; Jörg Hänze; Ludger Fink; Frank Rose; Werner Seeger; Friedrich Grimminger
Measurement of exhaled hydrogen peroxide from rabbit lungs.
Biological chemistry 2004;385(3-4):259-64.
2004: Norbert Weissmann; Ercan Akkayagil; Karin Quanz; Ralph Theo Schermuly; Hossein A Ghofrani; Ludger Fink; Jörg Hänze; Frank Rose; Werner Seeger; Friedrich Grimminger
Basic features of hypoxic pulmonary vasoconstriction in mice.
Respiratory physiology & neurobiology 2004;139(2):191-202.
2003: Alexander C Langheinrich; Ruediger C Braun-Dullaeus; Gerhard Walker; Ina Jeide; Ralph Schilling; Kai Tammoscheit; Thomas Dreyer; Ludger Fink; Rainer M Bohle; Werner Haberbosch
Effects of 3-deazaadenosine on homocysteine and atherosclerosis in apolipoprotein E-deficient mice.
Atherosclerosis 2003;171(2):181-92.
2003: Norbert Weissmann; Nadine Ebert; Marit Ahrens; Hossein A Ghofrani; Ralph Theo Schermuly; Jörg Hänze; Ludger Fink; Frank Rose; Jörg Conzen; Werner Seeger; Friedrich Grimminger
Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs.
American journal of respiratory cell and molecular biology 2003;29(6):721-32.
2003: Ludger Fink; Hans Hölschermann; Grazyna Kwapiszewska; Jai Prakash Muyal; Björn Lengemann; Rainer M Bohle; Sentot Santoso
Characterization of platelet-specific mRNA by real-time PCR after laser-assisted microdissection.
Thrombosis and haemostasis 2003;90(4):749-56.
2003: Daniel G Sedding; Ulrike Seay; Ludger Fink; Matthias Heil; Wolfgang Kummer; Harald Tillmanns; Ruediger C Braun-Dullaeus
Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells.
Circulation 2003;108(5):616-22.
2003: Jens Wolff; Cornelia Brendel; Ludger Fink; Rainer M Bohle; Karin Kissel; Juergen Bux
Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP- neutrophils from NB1 GP-expressing individuals and association of low expression with NB1 gene polymorphisms.
Blood 2003;102(2):731-3.
2003: Klaus Steger; Ludger Fink; Klaus Failing; Rainer M Bohle; Sabine Kliesch; Wolfgang Weidner; Martin Bergmann
Decreased protamine-1 transcript levels in testes from infertile men.
Molecular human reproduction 2003;9(6):331-6.
2003: Jochen Springer; Gerard P McGregor; Ludger Fink; Axel Fischer
Alternative splicing in single cells dissected from complex tissues: separate expression of prepro-tachykinin A mRNA splice variants in sensory neurones.
Journal of neurochemistry 2003;85(4):882-8.
2003: Norbert Weissmann; Matthias Nollen; Boris Gerigk; Hossein Ardeschir Ghofrani; Ralph Theo Schermuly; Andreas Gunther; Karin Quanz; Ludger Fink; Jörg Hänze; Frank Rose; Werner Seeger; Friedrich Grimminger
Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide.
American journal of physiology. Heart and circulatory physiology 2003;284(3):H931-8.
2002: Frank Rose; Friedrich Grimminger; Jutta Appel; Mathias Heller; Volker Pies; Norbert Weissmann; Ludger Fink; Sebastian Schmidt; Stefanie Krick; Gieri Camenisch; Max Gassmann; Werner Seeger; Jörg Hänze
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1660-1.
2002: Frank Rose; Bernd Guthmann; Tobias Tenenbaum; Ludger Fink; Ardeschir Ghofrani; Norbert Weissmann; Peter König; Leander Ermert; Gabriele Dahlem; Joerg Haenze; Wolfgang Kummer; Werner Seeger; Friedrich Grimminger
Apical, but not basolateral, endotoxin preincubation protects alveolar epithelial cells against hydrogen peroxide-induced loss of barrier function: the role of nitric oxide synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1474-81.
2002: Ulrich Grandel; Mathias Reutemann; Ladislau Kiss; Michael Buerke; Ludger Fink; Emmanoyil Bournelis; Martina Heep; Werner Seeger; Friedrich Grimminger; Ulf Sibelius
Staphylococcal alpha-toxin provokes neutrophil-dependent cardiac dysfunction: role of ICAM-1 and cys-leukotrienes.
American journal of physiology. Heart and circulatory physiology 2002;282(3):H1157-65.
2002: Ludger Fink; Rainer M Bohle
Internal standards for laser microdissection.
Methods in enzymology 2002;356():99-113.
2002: Ludger Fink; Stephanie Kohlhoff; Maria Magdalena Stein; Jörg Hänze; Norbert Weissmann; Frank Rose; Ercan Akkayagil; Daniel Manz; Friedrich Grimminger; Werner Seeger; Rainer M Bohle
cDNA array hybridization after laser-assisted microdissection from nonneoplastic tissue.
The American journal of pathology 2002;160(1):81-90.
2001: Katja Hattar; Ludger Fink; K Fietzner; B Himmel; Friedrich Grimminger; Werner Seeger; Ulf Sibelius
Cell density regulates neutrophil IL-8 synthesis: role of IL-1 receptor antagonist and soluble TNF receptors.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6287-93.
2001: Ulrich Grandel; Ulf Sibelius; J Schrickel; D Schmidt; Michael Buerke; Ludger Fink; Emmanoyil Bournelis; Martina Heep; Konstantin Mayer; Rainer M Bohle; Werner Seeger; Friedrich Grimminger
Biosynthesis of constitutive nitric oxide synthase-derived nitric oxide attenuates coronary vasoconstriction and myocardial depression in a model of septic heart failure induced by Staphylococcus aureus alpha-toxin.
Critical care medicine 2001;29(1):1-7.
2000: Ulrich Grandel; Ludger Fink; A Blum; Martina Heep; Michael Buerke; H J Kraemer; Konstantin Mayer; Rainer M Bohle; Werner Seeger; Friedrich Grimminger; Ulf Sibelius
Endotoxin-induced myocardial tumor necrosis factor-alpha synthesis depresses contractility of isolated rat hearts: evidence for a role of sphingosine and cyclooxygenase-2-derived thromboxane production.
Circulation 2000;102(22):2758-64.
2000: Ludger Fink; T Kinfe; Werner Seeger; Leander Ermert; Wolfgang Kummer; Rainer M Bohle
Immunostaining for cell picking and real-time mRNA quantitation.
The American journal of pathology 2000;157(5):1459-66.
2000: Hans Hölschermann; Rainer M Bohle; H Schmidt; H Zeller; Ludger Fink; U Stahl; Helmut Grimm; Harald Tillmanns; Werner Haberbosch
Hirudin reduces tissue factor expression and attenuates graft arteriosclerosis in rat cardiac allografts.
Circulation 2000;102(3):357-63.
2000: Ludger Fink; T Kinfe; Maria Magdalena Stein; Leander Ermert; Jörg Hänze; Wolfgang Kummer; Werner Seeger; Rainer M Bohle
Immunostaining and laser-assisted cell picking for mRNA analysis.
Laboratory investigation; a journal of technical methods and pathology 2000;80(3):327-33.
2000: Rainer M Bohle; E Hartmann; T Kinfe; Leander Ermert; Werner Seeger; Ludger Fink
Cell type-specific mRNA quantitation in non-neoplastic tissues after laser-assisted cell picking.
Pathobiology : journal of immunopathology, molecular and cellular biology 2000;68(4-5):191-5.
2000: Folker E Franke; Katharina Pauls; L Kerkman; Klaus Steger; Ludger Fink; Eberhard Burkhardt; Thomas Klonisch; Martin Bergmann; Sergei M Danilov
[CD143 expression in testicular germ cell tumors].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2000;84():199-209.
1999: Katharina Pauls; Ludger Fink; Folker E Franke
Angiotensin-converting enzyme (CD143) in neoplastic germ cells.
Laboratory investigation; a journal of technical methods and pathology 1999;79(11):1425-35.
1999: Ludger Fink; U Stahl; Leander Ermert; Wolfgang Kummer; Werner Seeger; Rainer M Bohle
Rat porphobilinogen deaminase gene: a pseudogene-free internal standard for laser-assisted cell picking.
BioTechniques 1999;26(3):510-6.
1999: Hans Hölschermann; Rainer M Bohle; H Zeller; H Schmidt; U Stahl; Ludger Fink; Helmut Grimm; Harald Tillmanns; Werner Haberbosch
In situ detection of tissue factor within the coronary intima in rat cardiac allograft vasculopathy.
The American journal of pathology 1999;154(1):211-20.
1998: Ludger Fink; W Seeger; Leander Ermert; Jörg Hänze; U Stahl; Friedrich Grimminger; W Kummer; R M Bohle
Real-time quantitative RT-PCR after laser-assisted cell picking.
Nature medicine 1998;4(11):1329-33.