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Brett Finlay
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
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Research Profile (preview)
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Physiology
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Network (preview)
26
Vallance, Bruce
24
Deng, Wanyin
21
Brumell, John
18
Brown, Nat
17
Coombes, Brian
17
Rosenshine, Ilan
15
Puente, José Luis
14
Wickham, Mark
13
Garcia-del Portillo, Francisco
13
Knodler, Leigh
12
Li, Yuling
12
Guttman, Julian
12
DeVinney, R
12
Steele-Mortimer, Olivia
11
Strynadka, Natalie
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All Publications
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2009: Menendez Alfredo; Arena Ellen T; Guttman Julian A; Thorson Lisa; Vallance Bruce A; Vogl Wayne; Finlay B Brett
Salmonella infection of gallbladder epithelial cells drives local inflammation and injury in a model of acute typhoid fever.
The Journal of infectious diseases 2009;200(11):1703-13.
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2009: Sekirov Inna; Finlay B Brett
The role of the intestinal microbiota in enteric infection.
The Journal of physiology 2009;587(Pt 17):4159-67.
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2009: Apel Dmitry; White Aaron P; Grassl Guntram A; Finlay B Brett; Surette Michael G
Long-term survival of Salmonella enterica serovar Typhimurium reveals an infectious state that is underrepresented on laboratory media containing bile salts.
Applied and environmental microbiology 2009;75(14):4923-5.
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2009: Willing B P; Finlay B B
Gut microbiology: fitting into the intestinal neighbourhood.
Current biology : CB 2009;19(11):R457-9.
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2009: Kum Winnie W S; Lee Sansan; Grassl Guntram A; Bidshahri Roza; Hsu Kimberly; Ziltener Hermann J; Finlay B Brett
Lack of functional P-selectin ligand exacerbates Salmonella serovar typhimurium infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6550-61.
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2009: Spreter Thomas; Yip Calvin K; Sanowar Sarah; André Ingemar; Kimbrough Tyler G; Vuckovic Marija; Pfuetzner Richard A; Deng Wanyin; Yu Angel C; Finlay B Brett; Baker David; Miller Samuel I; Strynadka Natalie C J
A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system.
Nature structural & molecular biology 2009;16(5):468-76.
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2009: Guttman Julian A; Finlay B Brett
Tight junctions as targets of infectious agents.
Biochimica et biophysica acta 2009;1788(4):832-41.
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2009: Valdez Yanet; Grassl Guntram A; Guttman Julian A; Coburn Bryan; Gros Phillipe; Vallance Bruce A; Finlay B Brett
Nramp1 drives an accelerated inflammatory response during Salmonella-induced colitis in mice.
Cellular microbiology 2009;11(2):351-62.
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2009: Shames Stephanie R; Auweter Sigrid D; Finlay B Brett
Co-evolution and exploitation of host cell signaling pathways by bacterial pathogens.
The international journal of biochemistry & cell biology 2009;41(2):380-9.
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2009: Sal-Man Neta; Biemans-Oldehinkel Esther; Finlay B Brett
Structural microengineers: pathogenic Escherichia coli redesigns the actin cytoskeleton in host cells.
Structure (London, England : 1993) 2009;17(1):15-9.
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2009: Valdez Yanet; Ferreira Rosana B R; Finlay B Brett
Molecular mechanisms of salmonella virulence and host resistance.
Current topics in microbiology and immunology 2009;337():93-127.
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2008: Guttman Julian A; Finlay B Brett
Subcellular alterations that lead to diarrhea during bacterial pathogenesis.
Trends in microbiology 2008;16(11):535-42.
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2008: Ivanov Ivaylo I; Frutos Rosa de Llanos; Manel Nicolas; Yoshinaga Keiji; Rifkin Daniel B; Sartor R Balfour; Finlay B Brett; Littman Dan R
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine.
Cell host & microbe 2008;4(4):337-49.
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2008: Sekirov Inna; Tam Nicola M; Jogova Maria; Robertson Marilyn L; Li Yuling; Lupp Claudia; Finlay B Brett
Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection.
Infection and immunity 2008;76(10):4726-36.
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2008: Yu Hong Bing; Finlay B Brett
The caspase-1 inflammasome: a pilot of innate immune responses.
Cell host & microbe 2008;4(3):198-208.
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2008: See Raymond H; Petric Martin; Lawrence David J; Mok Catherine P Y; Rowe Thomas; Zitzow Lois A; Karunakaran Karuna P; Voss Thomas G; Brunham Robert C; Gauldie Jack; Finlay B Brett; Roper Rachel L
Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines.
The Journal of general virology 2008;89(Pt 9):2136-46.
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2008: Mallo Gustavo V; Espina Marianela; Smith Adam C; Terebiznik Mauricio R; Alemán Ainel; Finlay B Brett; Rameh Lucia E; Grinstein Sergio; Brumell John H
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34.
The Journal of cell biology 2008;182(4):741-52.
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2008: Valdez Yanet; Diehl Gretchen E; Vallance Bruce A; Grassl Guntram A; Guttman Julian A; Brown Nat F; Rosenberger Carrie M; Littman Dan R; Gros Philippe; Finlay B Brett
Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection.
Cellular microbiology 2008;10(8):1646-61.
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2008: Champion Olivia L; Valdez Yanet; Thorson Lisa; Guttman Julian A; Menendez Alfredo; Gaynor Erin C; Finlay B Brett
A murine intraperitoneal infection model reveals that host resistance to Campylobacter jejuni is Nramp1 dependent.
Microbes and infection / Institut Pasteur 2008;10(8):922-7.
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2008: Bishop Jennifer L; Sly Laura M; Krystal Gerald; Finlay B Brett
The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo.
Infection and immunity 2008;76(7):2913-22.
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2008: Zarivach Raz; Deng Wanyin; Vuckovic Marija; Felise Heather B; Nguyen Hai V; Miller Samuel I; Finlay B Brett; Strynadka Natalie C J
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature 2008;453(7191):124-7.
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2008: Rogers Lindsay D; Kristensen Anders R; Boyle Erin C; Robinson Dale P; Ly Richard T; Finlay B Brett; Foster Leonard J
Identification of cognate host targets and specific ubiquitylation sites on the Salmonella SPI-1 effector SopB/SigD.
Journal of proteomics 2008;71(1):97-108.
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2008: Gal-Mor Ohad; Gibson Deanna L; Baluta Dan; Vallance Bruce A; Finlay B Brett
A novel secretion pathway of Salmonella enterica acts as an antivirulence modulator during salmonellosis.
PLoS pathogens 2008;4(4):e1000036.
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2008: Echtenkamp Frank; Deng Wanyin; Wickham Mark E; Vazquez Alejandra; Puente Jose L; Thanabalasuriar Ajitha; Gruenheid Samantha; Finlay B Brett; Hardwidge Philip R
Characterization of the NleF effector protein from attaching and effacing bacterial pathogens.
FEMS microbiology letters 2008;281(1):98-107.
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2008: Hu Qinghua; Coburn Bryan; Deng Wanyin; Li Yuling; Shi Xiaolu; Lan Quanxue; Wang Bing; Coombes Brian K; Finlay B Brett
Salmonella enterica serovar Senftenberg human clinical isolates lacking SPI-1.
Journal of clinical microbiology 2008;46(4):1330-6.
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2008: Coombes Brian K; Wickham Mark E; Mascarenhas Mariola; Gruenheid Samantha; Finlay B Brett; Karmali Mohamed A
Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains.
Applied and environmental microbiology 2008;74(7):2153-60.
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2008: García-Angulo Víctor A; Deng Wanyin; Thomas Nikhil A; Finlay B Brett; Puente Jose L
Regulation of expression and secretion of NleH, a new non-locus of enterocyte effacement-encoded effector in Citrobacter rodentium.
Journal of bacteriology 2008;190(7):2388-99.
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2008: Grassl Guntram A; Valdez Yanet; Bergstrom Kirk S B; Vallance Bruce A; Finlay B Brett
Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis.
Gastroenterology 2008;134(3):768-80.
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2008: Grassl Guntram A; Finlay B Brett
Pathogenesis of enteric Salmonella infections.
Current opinion in gastroenterology 2008;24(1):22-6.
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2007: Bakowski Malina A; Cirulis Judith T; Brown Nat F; Finlay B Brett; Brumell John H
SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion.
Cellular microbiology 2007;9(12):2839-55.
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2007: Veiga Esteban; Guttman Julian A; Bonazzi Matteo; Boucrot Emmanuel; Toledo-Arana Alejandro; Lin Ann E; Enninga Jost; Pizarro-Cerdá Javier; Finlay B Brett; Kirchhausen Tomas; Cossart Pascale
Invasive and adherent bacterial pathogens co-Opt host clathrin for infection.
Cell host & microbe 2007;2(5):340-51.
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2007: Asper David J; Sekirov Inna; Finlay B Brett; Rogan Dragan; Potter Andrew A
Cross reactivity of enterohemorrhagic Escherichia coli O157:H7-specific sera with non-O157 serotypes.
Vaccine 2007;25(49):8262-9.
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2007: Gal-Mor Ohad; Finlay B Brett
Pathogens on aspirin: promising research and therapeutic applications.
Nature methods 2007;4(11):893-4.
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2007: Pejcic-Karapetrovic Branka; Gurnani Komal; Russell Marsha S; Finlay B Brett; Sad Subash; Krishnan Lakshmi
Pregnancy impairs the innate immune resistance to Salmonella typhimurium leading to rapid fatal infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):6088-96.
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2007: Bhavsar Amit P; Guttman Julian A; Finlay B Brett
Manipulation of host-cell pathways by bacterial pathogens.
Nature 2007;449(7164):827-34.
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2007: Coburn Bryan; Sekirov Inna; Finlay B Brett
Type III secretion systems and disease.
Clinical microbiology reviews 2007;20(4):535-49.
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2007: Boyle Erin C; Brown Nat F; Brumell John H; Finlay B Brett
Src homology domain 2 adaptors affect adherence of Salmonella enterica serovar Typhimurium to non-phagocytic cells.
Microbiology (Reading, England) 2007;153(Pt 10):3517-26.
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2007: Thomas Nikhil A; Deng Wanyin; Baker Noel; Puente Jose; Finlay B Brett
Hierarchical delivery of an essential host colonization factor in enteropathogenic Escherichia coli.
The Journal of biological chemistry 2007;282(40):29634-45.
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2007: Lupp Claudia; Robertson Marilyn L; Wickham Mark E; Sekirov Inna; Champion Olivia L; Gaynor Erin C; Finlay B Brett
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae.
Cell host & microbe 2007;2(3):204.
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2007: Kim Jinoh; Thanabalasuriar Ajitha; Chaworth-Musters Tessa; Fromme J Chris; Frey Elizabeth A; Lario Paula I; Metalnikov Pavel; Rizg Keyrillos; Thomas Nikhil A; Lee Sau Fung; Hartland Elizabeth L; Hardwidge Philip R; Pawson Tony; Strynadka Natalie C; Finlay B Brett; Schekman Randy; Gruenheid Samantha
The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function.
Cell host & microbe 2007;2(3):160-71.
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2007: Lupp Claudia; Robertson Marilyn L; Wickham Mark E; Sekirov Inna; Champion Olivia L; Gaynor Erin C; Finlay B Brett
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae.
Cell host & microbe 2007;2(2):119-29.
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2007: Kenyon William J; Nicholson Kristy L; Rezuchova Bronislava; Homerova Dagmar; Garcia-del Portillo Francisco; Finlay B Brett; Pallen Mark J; Kormanec Jan; Spector Michael P
Sigma(s)-Dependent carbon-starvation induction of pbpG (PBP 7) is required for the starvation-stress response in Salmonella enterica serovar Typhimurium.
Microbiology (Reading, England) 2007;153(Pt 7):2148-58.
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2007: Wickham Mark E; Brown Nat F; Boyle Erin C; Coombes Brian K; Finlay B Brett
Virulence is positively selected by transmission success between mammalian hosts.
Current biology : CB 2007;17(9):783-8.
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2007: Mason David; Mallo Gustavo V; Terebiznik Mauricio R; Payrastre Bernard; Finlay B Brett; Brumell John H; Rameh Lucia; Grinstein Sergio
Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase.
The Journal of general physiology 2007;129(4):267-83.
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2007: Scott Monisha G; Dullaghan Edie; Mookherjee Neeloffer; Glavas Natalie; Waldbrook Matthew; Thompson Annick; Wang Aikun; Lee Ken; Doria Silvana; Hamill Pam; Yu Jie Jessie; Li Yuexin; Donini Oreola; Guarna M Marta; Finlay B Brett; North John R; Hancock Robert E W
An anti-infective peptide that selectively modulates the innate immune response.
Nature biotechnology 2007;25(4):465-72.
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2007: Finlay B Brett; Medzhitov Ruslan
Host-microbe interactions: fulfilling a niche.
Cell host & microbe 2007;1(1):3-4.
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2007: Wickham Mark E; Lupp Claudia; Vázquez Alejandra; Mascarenhas Mariola; Coburn Bryan; Coombes Brian K; Karmali Mohamed A; Puente José L; Deng Wanyin; Finlay B Brett
Citrobacter rodentium virulence in mice associates with bacterial load and the type III effector NleE.
Microbes and infection / Institut Pasteur 2007;9(3):400-7.
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2007: Boyle Erin C; Bishop Jennifer L; Grassl Guntram A; Finlay B Brett
Salmonella: from pathogenesis to therapeutics.
Journal of bacteriology 2007;189(5):1489-95.
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2007: Vaid K S; Guttman J A; Babyak N; Deng W; McNiven M A; Mochizuki N; Finlay B B; Vogl A W
The role of dynamin 3 in the testis.
Journal of cellular physiology 2007;210(3):644-54.
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2007: Guttman Julian A; Kazemi Pooya; Lin Ann E; Vogl A Wayne; Finlay B Brett
Desmosomes are unaltered during infections by attaching and effacing pathogens.
Anatomical record (Hoboken, N.J. : 2007) 2007;290(2):199-205.
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2007: Zarivach Raz; Vuckovic Marija; Deng Wanyin; Finlay B Brett; Strynadka Natalie C J
Structural analysis of a prototypical ATPase from the type III secretion system.
Nature structural & molecular biology 2007;14(2):131-7.
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2007: Jandu Narveen; Shen Songhai; Wickham Mark E; Prajapati Rohit; Finlay Brett B; Karmali Mohamed A; Sherman Philip M
Multiple seropathotypes of verotoxin-producing Escherichia coli (VTEC) disrupt interferon-gamma-induced tyrosine phosphorylation of signal transducer and activator of transcription (Stat)-1.
Microbial pathogenesis 2007;42(2-3):62-71.
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2007: Coombes Brian K; Lowden Michael J; Bishop Jennifer L; Wickham Mark E; Brown Nat F; Duong Nancy; Osborne Suzanne; Gal-Mor Ohad; Finlay B Brett
SseL is a salmonella-specific translocated effector integrated into the SsrB-controlled salmonella pathogenicity island 2 type III secretion system.
Infection and immunity 2007;75(2):574-80.
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2007: Coburn Bryan; Grassl Guntram A; Finlay B B
Salmonella, the host and disease: a brief review.
Immunology and cell biology 2007;85(2):112-8.
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2007: Bishop Jennifer L; Boyle Erin C; Finlay B Brett
Deception point: peptidoglycan modification as a means of immune evasion.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(3):691-2.
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2007: Grassl Guntram A; Finlay B Brett
Shigella rewrites host transcriptional responses.
Nature immunology 2007;8(1):15-6.
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2007: Zakhartchouk Alexander N; Sharon Chetna; Satkunarajah Malathy; Auperin Thierry; Viswanathan Sathiyanarayanan; Mutwiri George; Petric Martin; See Raymond H; Brunham Robert C; Finlay B Brett; Cameron Cheryl; Kelvin David J; Cochrane Alan; Rini James M; Babiuk Lorne A
Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: implications for a subunit vaccine.
Vaccine 2007;25(1):136-43.
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2007: Guttman Julian A; Samji Fereshte N; Li Yuling; Deng Wanyin; Lin Ann; Finlay B Brett
Aquaporins contribute to diarrhoea caused by attaching and effacing bacterial pathogens.
Cellular microbiology 2007;9(1):131-41.
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2007: Wickham Mark E; Brown Nat F; Provias John; Finlay B Brett; Coombes Brian K
Oral infection of mice with Salmonella enterica serovar Typhimurium causes meningitis and infection of the brain.
BMC infectious diseases 2007;7():65.
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2006: Finlay B Brett
Cellular microbiology in the 21st century.
Future microbiology 2006;1():359-61.
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2006: Boyle Erin C; Brown Nat F; Finlay B Brett
Salmonella enterica serovar Typhimurium effectors SopB, SopE, SopE2 and SipA disrupt tight junction structure and function.
Cellular microbiology 2006;8(12):1946-57.
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2006: Guttman Julian A; Samji Fereshte N; Li Yuling; Vogl A Wayne; Finlay B Brett
Evidence that tight junctions are disrupted due to intimate bacterial contact and not inflammation during attaching and effacing pathogen infection in vivo.
Infection and immunity 2006;74(11):6075-84.
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2006: Gal-Mor Ohad; Finlay B Brett
Pathogenicity islands: a molecular toolbox for bacterial virulence.
Cellular microbiology 2006;8(11):1707-19.
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2006: Ma Caixia; Wickham Mark E; Guttman Julian A; Deng Wanyin; Walker John; Madsen Karen L; Jacobson Kevan; Vogl Wayne A; Finlay B Brett; Vallance Bruce A
Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map).
Cellular microbiology 2006;8(10):1669-86.
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2006: Wickham Mark E; Lupp Claudia; Mascarenhas Mariola; Vazquez Alejandra; Coombes Brian K; Brown Nat F; Coburn Bryan A; Deng Wanyin; Puente Jose L; Karmali Mohamed A; Finlay B Brett
Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection.
The Journal of infectious diseases 2006;194(6):819-27.
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2006: Brown Nat F; Szeto Jason; Jiang Xiuju; Coombes Brian K; Finlay B Brett; Brumell John H
Mutational analysis of Salmonella translocated effector members SifA and SopD2 reveals domains implicated in translocation, subcellular localization and function.
Microbiology (Reading, England) 2006;152(Pt 8):2323-43.
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2006: Sekirov Inna; Finlay B Brett
Human and microbe: united we stand.
Nature medicine 2006;12(7):736-7.
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2006: Gal-Mor Ohad; Valdez Yanet; Finlay B Brett
The temperature-sensing protein TlpA is repressed by PhoP and dispensable for virulence of Salmonella enterica serovar Typhimurium in mice.
Microbes and infection / Institut Pasteur 2006;8(8):2154-62.
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2006: Brown Nat F; Wickham Mark E; Coombes Brian K; Finlay B Brett
Crossing the line: selection and evolution of virulence traits.
PLoS pathogens 2006;2(5):e42.
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2006: Khan Mohammed A; Ma Caixia; Knodler Leigh A; Valdez Yanet; Rosenberger Carrie M; Deng Wanyin; Finlay B Brett; Vallance Bruce A
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice.
Infection and immunity 2006;74(5):2522-36.
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2006: Hardwidge Philip R; Donohoe Sam; Aebersold Ruedi; Finlay B Brett
Proteomic analysis of the binding partners to enteropathogenic Escherichia coli virulence proteins expressed in Saccharomyces cerevisiae.
Proteomics 2006;6(7):2174-9.
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2006: Guttman Julian A; Li Yuling; Wickham Mark E; Deng Wanyin; Vogl A Wayne; Finlay B Brett
Attaching and effacing pathogen-induced tight junction disruption in vivo.
Cellular microbiology 2006;8(4):634-45.
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2006: See Raymond H; Zakhartchouk Alexander N; Petric Martin; Lawrence David J; Mok Catherine P Y; Hogan Robert J; Rowe Thomas; Zitzow Lois A; Karunakaran Karuna P; Hitt Mary M; Graham Frank L; Prevec Ludvik; Mahony James B; Sharon Chetna; Auperin Thierry C; Rini James M; Tingle Aubrey J; Scheifele David W; Skowronski Danuta M; Patrick David M; Voss Thomas G; Babiuk Lorne A; Gauldie Jack; Roper Rachel L; Brunham Robert C; Finlay B Brett
Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus.
The Journal of general virology 2006;87(Pt 3):641-50.
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2006: Linington Roger G; Robertson Marilyn; Gauthier Annick; Finlay B Brett; MacMillan John B; Molinski Tadeusz F; van Soest Rob; Andersen Raymond J
Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia.
Journal of natural products 2006;69(2):173-7.
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2006: Finlay B Brett; McFadden Grant
Anti-immunology: evasion of the host immune system by bacterial and viral pathogens.
Cell 2006;124(4):767-82.
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2006: Bishop Jennifer L; Finlay B Brett
Friend or foe? Antimicrobial peptides trigger pathogen virulence.
Trends in molecular medicine 2006;12(1):3-6.
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2006: Martin-Orozco Natalia; Touret Nicolas; Zaharik Michael L; Park Edwin; Kopelman Raoul; Miller Samuel; Finlay B Brett; Gros Philippe; Grinstein Sergio
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages.
Molecular biology of the cell 2006;17(1):498-510.
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2005: Barba Jeannette; Bustamante Víctor H; Flores-Valdez Mario A; Deng Wanyin; Finlay B Brett; Puente José L
A positive regulatory loop controls expression of the locus of enterocyte effacement-encoded regulators Ler and GrlA.
Journal of bacteriology 2005;187(23):7918-30.
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2005: Boyle Erin C; Finlay B Brett
Leaky guts and lipid rafts.
Trends in microbiology 2005;13(12):560-3.
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2005: Brown Nat F; Vallance Bruce A; Coombes Brian K; Valdez Yanet; Coburn Bryan A; Finlay B Brett
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine.
PLoS pathogens 2005;1(3):e32.
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2005: Coombes Brian K; Wickham Mark E; Lowden Michael J; Brown Nat F; Finlay B Brett
Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(48):17460-5.
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2005: Hsiao William W L; Ung Korine; Aeschliman Dana; Bryan Jenny; Finlay B Brett; Brinkman Fiona S L
Evidence of a large novel gene pool associated with prokaryotic genomic islands.
PLoS genetics 2005;1(5):e62.
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2005: Coombes Brian K; Coburn Bryan A; Potter Andrew A; Gomis Susantha; Mirakhur Kuldip; Li Yuling; Finlay B Brett
Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious enterocolitis.
Infection and immunity 2005;73(11):7161-9.
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2005: Gauthier Annick; Robertson Marilyn L; Lowden Michael; Ibarra J Antonio; Puente José Luis; Finlay B Brett
Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli.
Antimicrobial agents and chemotherapy 2005;49(10):4101-9.
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2005: Rodríguez-Escudero Isabel; Hardwidge Philip R; Nombela César; Cid Víctor J; Finlay B Brett; Molina María
Enteropathogenic Escherichia coli type III effectors alter cytoskeletal function and signalling in Saccharomyces cerevisiae.
Microbiology (Reading, England) 2005;151(Pt 9):2933-45.
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2005: Thomas Nikhil A; Deng Wanyin; Puente Jose L; Frey Elizabeth A; Yip Calvin K; Strynadka Natalie C J; Finlay B Brett
CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE- and non-LEE-encoded effectors of enteropathogenic Escherichia coli.
Molecular microbiology 2005;57(6):1762-79.
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2005: Yip Calvin K; Kimbrough Tyler G; Felise Heather B; Vuckovic Marija; Thomas Nikhil A; Pfuetzner Richard A; Frey Elizabeth A; Finlay B Brett; Miller Samuel I; Strynadka Natalie C J
Structural characterization of the molecular platform for type III secretion system assembly.
Nature 2005;435(7042):702-7.
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2005: Coburn Bryan; Li Yuling; Owen David; Vallance Bruce A; Finlay B Brett
Salmonella enterica serovar Typhimurium pathogenicity island 2 is necessary for complete virulence in a mouse model of infectious enterocolitis.
Infection and immunity 2005;73(6):3219-27.
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2005: Hardwidge Philip R; Deng Wanyin; Vallance Bruce A; Rodriguez-Escudero Isabel; Cid Victor J; Molina Maria; Finlay B Brett
Modulation of host cytoskeleton function by the enteropathogenic Escherichia coli and Citrobacter rodentium effector protein EspG.
Infection and immunity 2005;73(5):2586-94.
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2005: Coombes Brian K; Wickham Mark E; Brown Nat F; Lemire Sebastien; Bossi Lionello; Hsiao William W L; Brinkman Fiona S L; Finlay B Brett
Genetic and molecular analysis of GogB, a phage-encoded type III-secreted substrate in Salmonella enterica serovar typhimurium with autonomous expression from its associated phage.
Journal of molecular biology 2005;348(4):817-30.
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2005: Lupp Claudia; Finlay B Brett
Intestinal microbiota.
Current biology : CB 2005;15(7):R235-6.
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2005: Deng Wanyin; Li Yuling; Hardwidge Philip R; Frey Elizabeth A; Pfuetzner Richard A; Lee Sansan; Gruenheid Samantha; Strynakda Natalie C J; Puente Jose L; Finlay B Brett
Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens.
Infection and immunity 2005;73(4):2135-46.
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2005: Coombes Brian K; Finlay B Brett
Insertion of the bacterial type III translocon: not your average needle stick.
Trends in microbiology 2005;13(3):92-5.
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2005: Knodler Leigh A; Finlay B Brett; Steele-Mortimer Olivia
The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt.
The Journal of biological chemistry 2005;280(10):9058-64.
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2005: Yip Calvin K; Finlay B Brett; Strynadka Natalie C J
Structural characterization of a type III secretion system filament protein in complex with its chaperone.
Nature structural & molecular biology 2005;12(1):75-81.
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2005: Finlay B B
Bacterial virulence strategies that utilize Rho GTPases.
Current topics in microbiology and immunology 2005;291():1-10.
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2004: Jiang Xiuju; Rossanese Olivia W; Brown Nat F; Kujat-Choy Sonya; Galán Jorge E; Finlay B Brett; Brumell John H
The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice.
Molecular microbiology 2004;54(5):1186-98.
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2004: Coombes Brian K; Brown Nat F; Valdez Yanet; Brumell John H; Finlay B Brett
Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion apparatus and SsaL.
The Journal of biological chemistry 2004;279(48):49804-15.
-
2004: Coombes Brian K; Valdez Yanet; Finlay B Brett
Evasive maneuvers by secreted bacterial proteins to avoid innate immune responses.
Current biology : CB 2004;14(19):R856-67.
-
2004: Zaharik Michelle L; Cullen Vivian Li; Fung Angela M; Libby Stephen J; Kujat Choy Sonya L; Coburn Bryan; Kehres David G; Maguire Michael E; Fang Ferric C; Finlay B Brett
The Salmonella enterica serovar typhimurium divalent cation transport systems MntH and SitABCD are essential for virulence in an Nramp1G169 murine typhoid model.
Infection and immunity 2004;72(9):5522-5.
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2004: Conlin Victoria S; Curtis Susan B; Zhao Ying; Moore Edwin D W; Smith Valerie C; Meloche R Mark; Finlay B Brett; Buchan Alison M J
Helicobacter pylori infection targets adherens junction regulatory proteins and results in increased rates of migration in human gastric epithelial cells.
Infection and immunity 2004;72(9):5181-92.
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2004: Kujat Choy Sonya L; Boyle Erin C; Gal-Mor Ohad; Goode David L; Valdez Yanet; Vallance Bruce A; Finlay B Brett
SseK1 and SseK2 are novel translocated proteins of Salmonella enterica serovar typhimurium.
Infection and immunity 2004;72(9):5115-25.
-
2004: Finlay B Brett; See Raymond H; Brunham Robert C
Rapid response research to emerging infectious diseases: lessons from SARS.
Nature reviews. Microbiology 2004;2(7):602-7.
-
2004: Pollard Andrew J; Currie Andrew; Rosenberger Carrie M; Heale John-Paul; Finlay B Brett; Speert David P
Differential post-transcriptional activation of human phagocytes by different Pseudomonas aeruginosa isolates.
Cellular microbiology 2004;6(7):639-50.
-
2004: Harrison Rene E; Brumell John H; Khandani Arian; Bucci Cecilia; Scott Cameron C; Jiang Xiuju; Finlay B Brett; Grinstein Sergio
Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles.
Molecular biology of the cell 2004;15(7):3146-54.
-
2004: Maaser Christian; Housley Michael P; Iimura Mitsutoshi; Smith Jennifer R; Vallance Bruce A; Finlay B Brett; Schreiber John R; Varki Nissi M; Kagnoff Martin F; Eckmann Lars
Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies.
Infection and immunity 2004;72(6):3315-24.
-
2004: Finlay B Brett; Hancock Robert E W
Can innate immunity be enhanced to treat microbial infections?
Nature reviews. Microbiology 2004;2(6):497-504.
-
2004: Vazquez-Torres Andrés; Vallance Bruce A; Bergman Molly A; Finlay B Brett; Cookson Brad T; Jones-Carson Jessica; Fang Ferric C
Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):6202-8.
-
2004: Hardwidge Philip R; Rodriguez-Escudero Isabel; Goode David; Donohoe Sam; Eng Jimmy; Goodlett David R; Aebersold Reudi; Finlay B Brett
Proteomic analysis of the intestinal epithelial cell response to enteropathogenic Escherichia coli.
The Journal of biological chemistry 2004;279(19):20127-36.
-
2004: Zaharik Michelle L; Finlay B Brett
Mn2+ and bacterial pathogenesis.
Frontiers in bioscience : a journal and virtual library 2004;9():1035-42.
-
2004: Thomas N A; Finlay B B
Pathogens: bacterial needles ruled to length and specificity.
Current biology : CB 2004;14(5):R192-4.
-
2004: Deng Wanyin; Puente José L; Gruenheid Samantha; Li Yuling; Vallance Bruce A; Vázquez Alejandra; Barba Jeannette; Ibarra J Antonio; O'Donnell Paul; Metalnikov Pavel; Ashman Keith; Lee Sansan; Goode David; Pawson Tony; Finlay B Brett
Dissecting virulence: systematic and functional analyses of a pathogenicity island.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(10):3597-602.
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2004: Gruenheid Samantha; Sekirov Inna; Thomas Nikhil A; Deng Wanyin; O'Donnell Paul; Goode David; Li Yuling; Frey Elizabeth A; Brown Nathaniel F; Metalnikov Pavel; Pawson Tony; Ashman Keith; Finlay B Brett
Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7.
Molecular microbiology 2004;51(5):1233-49.
-
2004: Rosenberger Carrie M; Gallo Richard L; Finlay B Brett
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2422-7.
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2004: Potter Andrew A; Klashinsky Sandra; Li Yuling; Frey Elizabeth; Townsend Hugh; Rogan Dragan; Erickson Galen; Hinkley Susanne; Klopfenstein Terry; Moxley Rodney A; Smith David R; Finlay B Brett
Decreased shedding of Escherichia coli O157:H7 by cattle following vaccination with type III secreted proteins.
Vaccine 2004;22(3-4):362-9.
-
2004: Coombes Brian K; Hardwidge Philip R; Finlay B Brett
Interpreting the host-pathogen dialogue through microarrays.
Advances in applied microbiology 2004;54():291-331.
-
2003: Gauthier Annick; Finlay B Brett
Translocated intimin receptor and its chaperone interact with ATPase of the type III secretion apparatus of enteropathogenic Escherichia coli.
Journal of bacteriology 2003;185(23):6747-55.
-
2003: Boyle Erin C; Finlay B Brett
Bacterial pathogenesis: exploiting cellular adherence.
Current opinion in cell biology 2003;15(5):633-9.
-
2003: Knodler Leigh A; Vallance Bruce A; Hensel Michael; Jäckel Daniela; Finlay B Brett; Steele-Mortimer Olivia
Salmonella type III effectors PipB and PipB2 are targeted to detergent-resistant microdomains on internal host cell membranes.
Molecular microbiology 2003;49(3):685-704.
-
2003: Gauthier Annick; Thomas Nikhil A; Finlay B Brett
Bacterial injection machines.
The Journal of biological chemistry 2003;278(28):25273-6.
-
2003: Coombes Brian K; Brown Nat F; Kujat-Choy Sonya; Vallance Bruce A; Finlay B Brett
SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells.
Microbes and infection / Institut Pasteur 2003;5(7):561-70.
-
2003: Vallance Bruce A; Deng Wanyin; Jacobson Kevan; Finlay B Brett
Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium.
Infection and immunity 2003;71(6):3443-53.
-
2003: Gauthier Annick; Puente Jose Luis; Finlay B Brett
Secretin of the enteropathogenic Escherichia coli type III secretion system requires components of the type III apparatus for assembly and localization.
Infection and immunity 2003;71(6):3310-9.
-
2003: Rosenberger Carrie M; Finlay B Brett
Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens.
Nature reviews. Molecular cell biology 2003;4(5):385-96.
-
2003: Gruenheid Samantha; Finlay B Brett
Microbial pathogenesis and cytoskeletal function.
Nature 2003;422(6933):775-81.
-
2003: Kurz C Léopold; Chauvet Sophie; Andrès Emmanuel; Aurouze Marianne; Vallet Isabelle; Michel Gérard P F; Uh Mitch; Celli Jean; Filloux Alain; De Bentzmann Sophie; Steinmetz Ivo; Hoffmann Jules A; Finlay B Brett; Gorvel Jean-Pierre; Ferrandon Dominique; Ewbank Jonathan J
Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening.
The EMBO journal 2003;22(7):1451-60.
-
2003: Deng Wanyin; Vallance Bruce A; Li Yuling; Puente Jose L; Finlay B Brett
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice.
Molecular microbiology 2003;48(1):95-115.
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2003: Brumell John H; Kujat-Choy Sonya; Brown Nat F; Vallance Bruce A; Knodler Leigh A; Finlay B Brett
SopD2 is a novel type III secreted effector of Salmonella typhimurium that targets late endocytic compartments upon delivery into host cells.
Traffic (Copenhagen, Denmark) 2003;4(1):36-48.
-
2002: Horne Cathy; Vallance Bruce A; Deng Wanyin; Finlay B Brett
Current progress in enteropathogenic and enterohemorrhagic Escherichia coli vaccines.
Expert review of vaccines 2002;1(4):483-93.
-
2002: Vallance Bruce A; Chan Crystal; Robertson Marilyn L; Finlay B Brett
Enteropathogenic and enterohemorrhagic Escherichia coli infections: emerging themes in pathogenesis and prevention.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie 2002;16(11):771-8.
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2002: Zaharik Michelle L; Vallance Bruce A; Puente Jose L; Gros Philippe; Finlay B Brett
Host-pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15705-10.
-
2002: Linington Roger G; Robertson Marilyn; Gauthier Annick; Finlay B Brett; van Soest Rob; Andersen Raymond J
Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia.
Organic letters 2002;4(23):4089-92.
-
2002: Vallance Bruce A; Deng Wanyin; De Grado Myriam; Chan Crystal; Jacobson Kevan; Finlay B Brett
Modulation of inducible nitric oxide synthase expression by the attaching and effacing bacterial pathogen citrobacter rodentium in infected mice.
Infection and immunity 2002;70(11):6424-35.
-
2002: Terebiznik Mauricio R; Vieira Otilia V; Marcus Sandra L; Slade Andrea; Yip Christopher M; Trimble William S; Meyer Tobias; Finlay B Brett; Grinstein Sergio
Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella.
Nature cell biology 2002;4(10):766-73.
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2002: Brinkman Fiona S L; Blanchard Jeffrey L; Cherkasov Artem; Av-Gay Yossef; Brunham Robert C; Fernandez Rachel C; Finlay B Brett; Otto Sarah P; Ouellette B F Francis; Keeling Patrick J; Rose Ann M; Hancock Robert E W; Jones Steven J M; Greberg Hans
Evidence that plant-like genes in Chlamydia species reflect an ancestral relationship between Chlamydiaceae, cyanobacteria, and the chloroplast.
Genome research 2002;12(8):1159-67.
-
2002: Marcus Sandra L; Knodler Leigh A; Finlay B Brett
Salmonella enterica serovar Typhimurium effector SigD/SopB is membrane-associated and ubiquitinated inside host cells.
Cellular microbiology 2002;4(7):435-46.
-
2002: Brumell John H; Tang Patrick; Zaharik Michelle L; Finlay B Brett
Disruption of the Salmonella-containing vacuole leads to increased replication of Salmonella enterica serovar typhimurium in the cytosol of epithelial cells.
Infection and immunity 2002;70(6):3264-70.
-
2002: Brumell John H; Goosney Danika L; Finlay B Brett
SifA, a type III secreted effector of Salmonella typhimurium, directs Salmonella-induced filament (Sif) formation along microtubules.
Traffic (Copenhagen, Denmark) 2002;3(6):407-15.
-
2002: Celli Jean; Finlay B Brett
Bacterial avoidance of phagocytosis.
Trends in microbiology 2002;10(5):232-7.
-
2002: Rosenberger Carrie M; Finlay B Brett
Macrophages inhibit Salmonella typhimurium replication through MEK/ERK kinase and phagocyte NADPH oxidase activities.
The Journal of biological chemistry 2002;277(21):18753-62.
-
2002: Vallance Bruce A; Deng Wanyin; Knodler Leigh A; Finlay B Brett
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection.
Infection and immunity 2002;70(4):2070-81.
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2002: Zaharik Michelle L; Gruenheid Samantha; Perrin Andrew J; Finlay B Brett
Delivery of dangerous goods: type III secretion in enteric pathogens.
International journal of medical microbiology : IJMM 2002;291(8):593-603.
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2002: Knodler Leigh A; Celli Jean; Hardt Wolf-Dietrich; Vallance Bruce A; Yip Calvin; Finlay B Brett
Salmonella effectors within a single pathogenicity island are differentially expressed and translocated by separate type III secretion systems.
Molecular microbiology 2002;43(5):1089-103.
-
2002: Steele-Mortimer Olivia; Brumell John H; Knodler Leigh A; Méresse Stephane; Lopez Ana; Finlay B Brett
The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells.
Cellular microbiology 2002;4(1):43-54.
-
2002: Brumell J H; Perrin A J; Goosney D L; Finlay B B
Microbial pathogenesis: new niches for salmonella.
Current biology : CB 2002;12(1):R15-7.
-
2002: Cuellar-Mata Patricia; Jabado Nada; Liu Jun; Furuya Wendy; Finlay B Brett; Gros Philippe; Grinstein Sergio
Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages.
The Journal of biological chemistry 2002;277(3):2258-65.
-
2001: Luo Y; Bertero M G; Frey E A; Pfuetzner R A; Wenk M R; Creagh L; Marcus S L; Lim D; Sicheri F; Kay C; Haynes C; Finlay B B; Strynadka N C
Structural and biochemical characterization of the type III secretion chaperones CesT and SigE.
Nature structural biology 2001;8(12):1031-6.
-
2001: Rosenberger C M; Pollard A J; Finlay B B
Gene array technology to determine host responses to Salmonella.
Microbes and infection / Institut Pasteur 2001;3(14-15):1353-60.
-
2001: Knodler L A; Finlay B B
Salmonella and apoptosis: to live or let die?
Microbes and infection / Institut Pasteur 2001;3(14-15):1321-6.
-
2001: Deng W; Li Y; Vallance B A; Finlay B B
Locus of enterocyte effacement from Citrobacter rodentium: sequence analysis and evidence for horizontal transfer among attaching and effacing pathogens.
Infection and immunity 2001;69(10):6323-35.
-
2001: de Grado M; Rosenberger C M; Gauthier A; Vallance B A; Finlay B B
Enteropathogenic Escherichia coli infection induces expression of the early growth response factor by activating mitogen-activated protein kinase cascades in epithelial cells.
Infection and immunity 2001;69(10):6217-24.
-
2001: DeVinney R; Puente J L; Gauthier A; Goosney D; Finlay B B
Enterohaemorrhagic and enteropathogenic Escherichia coli use a different Tir-based mechanism for pedestal formation.
Molecular microbiology 2001;41(6):1445-58.
-
2001: Brumell J H; Tang P; Mills S D; Finlay B B
Characterization of Salmonella-induced filaments (Sifs) reveals a delayed interaction between Salmonella-containing vacuoles and late endocytic compartments.
Traffic (Copenhagen, Denmark) 2001;2(9):643-53.
-
2001: Gruenheid S; DeVinney R; Bladt F; Goosney D; Gelkop S; Gish G D; Pawson T; Finlay B B
Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells.
Nature cell biology 2001;3(9):856-9.
-
2001: Knodler L A; Celli J; Finlay B B
Pathogenic trickery: deception of host cell processes.
Nature reviews. Molecular cell biology 2001;2(8):578-88.
-
2001: Heczko U; Carthy C M; O'Brien B A; Finlay B B
Decreased apoptosis in the ileum and ileal Peyer's patches: a feature after infection with rabbit enteropathogenic Escherichia coli O103.
Infection and immunity 2001;69(7):4580-9.
-
2001: Finlay B B
Microbiology. Cracking Listeria's password.
Science (New York, N.Y.) 2001;292(5522):1665-7.
-
2001: Goosney D L; DeVinney R; Finlay B B
Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals.
Infection and immunity 2001;69(5):3315-22.
-
2001: Gauthier A; Finlay B B
Bacterial pathogenesis: the answer to virulence is in the pore.
Current biology : CB 2001;11(7):R264-7.
-
2001: Marcus S L; Wenk M R; Steele-Mortimer O; Finlay B B
A synaptojanin-homologous region of Salmonella typhimurium SigD is essential for inositol phosphatase activity and Akt activation.
FEBS letters 2001;494(3):201-7.
-
2001: Celli J; Olivier M; Finlay B B
Enteropathogenic Escherichia coli mediates antiphagocytosis through the inhibition of PI 3-kinase-dependent pathways.
The EMBO journal 2001;20(6):1245-58.
-
2001: Brumell J H; Rosenberger C M; Gotto G T; Marcus S L; Finlay B B
SifA permits survival and replication of Salmonella typhimurium in murine macrophages.
Cellular microbiology 2001;3(2):75-84.
-
2001: Coppolino M G; Kong C; Mohtashami M; Schreiber A D; Brumell J H; Finlay B B; Grinstein S; Trimble W S
Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis.
The Journal of biological chemistry 2001;276(7):4772-80.
-
2001: Devinney R; Nisan I; Ruschkowski S; Rosenshine I; Finlay B B
Tir tyrosine phosphorylation and pedestal formation are delayed in enteropathogenic Escherichia coli sepZ::TnphoA mutant 30-5-1(3).
Infection and immunity 2001;69(1):559-63.
-
2000: Steele-Mortimer O; Knodler L A; Marcus S L; Scheid M P; Goh B; Pfeifer C G; Duronio V; Finlay B B
Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD.
The Journal of biological chemistry 2000;275(48):37718-24.
-
2000: Heczko U; Smith V C; Mark Meloche R; Buchan A M; Finlay B B
Characteristics of Helicobacter pylori attachment to human primary antral epithelial cells.
Microbes and infection / Institut Pasteur 2000;2(14):1669-76.
-
2000: Rosenberger C M; Brumell J H; Finlay B B
Microbial pathogenesis: lipid rafts as pathogen portals.
Current biology : CB 2000;10(22):R823-5.
-
2000: Gruenheid S; Finlay B B
Crowd control: quorum sensing in pathogenic E. coli.
Trends in microbiology 2000;8(10):442-3.
-
2000: Scott M G; Rosenberger C M; Gold M R; Finlay B B; Hancock R E
An alpha-helical cationic antimicrobial peptide selectively modulates macrophage responses to lipopolysaccharide and directly alters macrophage gene expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3358-65.
-
2000: Steele-Mortimer O; St-Louis M; Olivier M; Finlay B B
Vacuole acidification is not required for survival of Salmonella enterica serovar typhimurium within cultured macrophages and epithelial cells.
Infection and immunity 2000;68(9):5401-4.
-
2000: Li Y; Frey E; Mackenzie A M; Finlay B B
Human response to Escherichia coli O157:H7 infection: antibodies to secreted virulence factors.
Infection and immunity 2000;68(9):5090-5.
-
2000: Vallance B A; Finlay B B
Exploitation of host cells by enteropathogenic Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):8799-806.
-
2000: Gauthier A; de Grado M; Finlay B B
Mechanical fractionation reveals structural requirements for enteropathogenic Escherichia coli Tir insertion into host membranes.
Infection and immunity 2000;68(7):4344-8.
-
2000: Luo Y; Frey E A; Pfuetzner R A; Creagh A L; Knoechel D G; Haynes C A; Finlay B B; Strynadka N C
Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex.
Nature 2000;405(6790):1073-7.
-
2000: Goosney D L; DeVinney R; Pfuetzner R A; Frey E A; Strynadka N C; Finlay B B
Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin.
Current biology : CB 2000;10(12):735-8.
-
2000: Kehres D G; Zaharik M L; Finlay B B; Maguire M E
The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen.
Molecular microbiology 2000;36(5):1085-100.
-
2000: Rosenberger C M; Scott M G; Gold M R; Hancock R E; Finlay B B
Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):5894-904.
-
2000: Finlay B B; Brumell J H
Salmonella interactions with host cells: in vitro to in vivo.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1397):623-31.
-
2000: Brumell J H; Marcus S L; Finlay B B
N-terminal conservation of putative type III secreted effectors of Salmonella typhimurium.
Molecular microbiology 2000;36(3):773-4.
-
2000: Heczko U; Abe A; Finlay B B
Segmented filamentous bacteria prevent colonization of enteropathogenic Escherichia coli O103 in rabbits.
The Journal of infectious diseases 2000;181(3):1027-33.
-
2000: Cordeiro C; Wiseman D J; Lutwyche P; Uh M; Evans J C; Finlay B B; Webb M S
Antibacterial efficacy of gentamicin encapsulated in pH-sensitive liposomes against an in vivo Salmonella enterica serovar typhimurium intracellular infection model.
Antimicrobial agents and chemotherapy 2000;44(3):533-9.
-
2000: Steele-Mortimer O; Knodler L A; Finlay B B
Poisons, ruffles and rockets: bacterial pathogens and the host cell cytoskeleton.
Traffic (Copenhagen, Denmark) 2000;1(2):107-18.
-
2000: Celli J; Deng W; Finlay B B
Enteropathogenic Escherichia coli (EPEC) attachment to epithelial cells: exploiting the host cell cytoskeleton from the outside.
Cellular microbiology 2000;2(1):1-9.
-
2000: Marcus S L; Brumell J H; Pfeifer C G; Finlay B B
Salmonella pathogenicity islands: big virulence in small packages.
Microbes and infection / Institut Pasteur 2000;2(2):145-56.
-
2000: Hirakata Y; Finlay B B; Simpson D A; Kohno S; Kamihira S; Speert D P
Penetration of clinical isolates of Pseudomonas aeruginosa through MDCK epithelial cell monolayers.
The Journal of infectious diseases 2000;181(2):765-9.
-
2000: Heczko U; Abe A; Finlay B B
In vivo interactions of rabbit enteropathogenic Escherichia coli O103 with its host: an electron microscopic and histopathologic study.
Microbes and infection / Institut Pasteur 2000;2(1):5-16.
-
2000: DeVinney R; Steele-Mortimer O; Finlay B B
Phosphatases and kinases delivered to the host cell by bacterial pathogens.
Trends in microbiology 2000;8(1):29-33.
-
2000: Goosney D L; Gruenheid S; Finlay B B
Gut feelings: enteropathogenic E. coli (EPEC) interactions with the host.
Annual review of cell and developmental biology 2000;16():173-89.
-
1999: Spector M P; Garcia del Portillo F; Bearson S M; Mahmud A; Magut M; Finlay B B; Dougan G; Foster J W; Pallen M J
The rpoS-dependent starvation-stress response locus stiA encodes a nitrate reductase (narZYWV) required for carbon-starvation-inducible thermotolerance and acid tolerance in Salmonella typhimurium.
Microbiology (Reading, England) 1999;145 ( Pt 11)():3035-45.
-
1999: Pfeifer C G; Marcus S L; Steele-Mortimer O; Knodler L A; Finlay B B
Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells.
Infection and immunity 1999;67(11):5690-8.
-
1999: Abe A; de Grado M; Pfuetzner R A; Sánchez-Sanmartín C; Devinney R; Puente J L; Strynadka N C; Finlay B B
Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion.
Molecular microbiology 1999;33(6):1162-75.
-
1999: Steele-Mortimer O; Méresse S; Gorvel J P; Toh B H; Finlay B B
Biogenesis of Salmonella typhimurium-containing vacuoles in epithelial cells involves interactions with the early endocytic pathway.
Cellular microbiology 1999;1(1):33-49.
-
1999: de Grado M; Abe A; Gauthier A; Steele-Mortimer O; DeVinney R; Finlay B B
Identification of the intimin-binding domain of Tir of enteropathogenic Escherichia coli.
Cellular microbiology 1999;1(1):7-17.
-
1999: DeVinney R; Gauthier A; Abe A; Finlay B B
Enteropathogenic Escherichia coli: a pathogen that inserts its own receptor into host cells.
Cellular and molecular life sciences : CMLS 1999;55(6-7):961-76.
-
1999: DeVinney R; Stein M; Reinscheid D; Abe A; Ruschkowski S; Finlay B B
Enterohemorrhagic Escherichia coli O157:H7 produces Tir, which is translocated to the host cell membrane but is not tyrosine phosphorylated.
Infection and immunity 1999;67(5):2389-98.
-
1999: Govoni G; Canonne-Hergaux F; Pfeifer C G; Marcus S L; Mills S D; Hackam D J; Grinstein S; Malo D; Finlay B B; Gros P
Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7.
Infection and immunity 1999;67(5):2225-32.
-
1999: Brumell J H; Steele-Mortimer O; Finlay B B
Bacterial invasion: Force feeding by Salmonella.
Current biology : CB 1999;9(8):R277-80.
-
1999: Goosney D L; Knoechel D G; Finlay B B
Enteropathogenic E. coli, Salmonella, and Shigella: masters of host cell cytoskeletal exploitation.
Emerging infectious diseases 1999;5(2):216-23.
-
1999: DeVinney R; Knoechel D G; Finlay B B
Enteropathogenic Escherichia coli: cellular harassment.
Current opinion in microbiology 1999;2(1):83-8.
-
1999: Finlay B B
Bacterial disease in diverse hosts.
Cell 1999;96(3):315-8.
-
1999: Goosney D L; Celli J; Kenny B; Finlay B B
Enteropathogenic Escherichia coli inhibits phagocytosis.
Infection and immunity 1999;67(2):490-5.
-
1999: Spector M P; DiRusso C C; Pallen M J; Garcia del Portillo F; Dougan G; Finlay B B
The medium-/long-chain fatty acyl-CoA dehydrogenase (fadF) gene of Salmonella typhimurium is a phase 1 starvation-stress response (SSR) locus.
Microbiology (Reading, England) 1999;145 ( Pt 1)():15-31.
-
1999: Goosney D L; de Grado M; Finlay B B
Putting E. coli on a pedestal: a unique system to study signal transduction and the actin cytoskeleton.
Trends in cell biology 1999;9(1):11-4.
-
1998: Gauthier A; Finlay B B
Protein translocation: delivering virulence into the host cell.
Current biology : CB 1998;8(21):R768-70.
-
1998: Lutwyche P; Cordeiro C; Wiseman D J; St-Louis M; Uh M; Hope M J; Webb M S; Finlay B B
Intracellular delivery and antibacterial activity of gentamicin encapsulated in pH-sensitive liposomes.
Antimicrobial agents and chemotherapy 1998;42(10):2511-20.
-
1998: Wilson D R; Siebers A; Finlay B B
Antigenic analysis of Bordetella pertussis filamentous hemagglutinin with phage display libraries and rabbit anti-filamentous hemagglutinin polyclonal antibodies.
Infection and immunity 1998;66(10):4884-94.
-
1998: Mills S D; Finlay B B
Isolation and characterization of Salmonella typhimurium and Yersinia pseudotuberculosis-containing phagosomes from infected mouse macrophages: Y. pseudotuberculosis traffics to terminal lysosomes where they are degraded.
European journal of cell biology 1998;77(1):35-47.
-
1998: Ortiz-Alvarez O; Yu D T; Petty R E; Finlay B B
HLA-B27 does not affect invasion of arthritogenic bacteria into human cells.
The Journal of rheumatology 1998;25(9):1765-71.
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1998: Richter-Dahlfors A; Heczko U; Meloche R M; Finlay B B; Buchan A M
Helicobacter pylori-infected human antral primary cell cultures: effect on gastrin cell function.
The American journal of physiology 1998;275(3 Pt 1):G393-401.
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1998: Wilson D R; Finlay B B
Phage display: applications, innovations, and issues in phage and host biology.
Canadian journal of microbiology 1998;44(4):313-29.
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1998: Mills S D; Ruschkowski S R; Stein M A; Finlay B B
Trafficking of porin-deficient Salmonella typhimurium mutants inside HeLa cells: ompR and envZ mutants are defective for the formation of Salmonella-induced filaments.
Infection and immunity 1998;66(4):1806-11.
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1998: Tang P; Sutherland C L; Gold M R; Finlay B B
Listeria monocytogenes invasion of epithelial cells requires the MEK-1/ERK-2 mitogen-activated protein kinase pathway.
Infection and immunity 1998;66(3):1106-12.
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1998: Frey E A; Finlay B B
Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14 dependent pathway.
Microbial pathogenesis 1998;24(2):101-9.
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1997: Kenny B; DeVinney R; Stein M; Reinscheid D J; Frey E A; Finlay B B
Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells.
Cell 1997;91(4):511-20.
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1997: Mills S D; Boland A; Sory M P; van der Smissen P; Kerbourch C; Finlay B B; Cornelis G R
Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type III secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12638-43.
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1997: Abe A; Kenny B; Stein M; Finlay B B
Characterization of two virulence proteins secreted by rabbit enteropathogenic Escherichia coli, EspA and EspB, whose maximal expression is sensitive to host body temperature.
Infection and immunity 1997;65(9):3547-55.
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1997: Richter-Dahlfors A; Buchan A M; Finlay B B
Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo.
The Journal of experimental medicine 1997;186(4):569-80.
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1997: Kenny B; Abe A; Stein M; Finlay B B
Enteropathogenic Escherichia coli protein secretion is induced in response to conditions similar to those in the gastrointestinal tract.
Infection and immunity 1997;65(7):2606-12.
-
1997: Kenny B; Finlay B B
Intimin-dependent binding of enteropathogenic Escherichia coli to host cells triggers novel signaling events, including tyrosine phosphorylation of phospholipase C-gamma1.
Infection and immunity 1997;65(7):2528-36.
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1997: Finlay B B; Falkow S
Common themes in microbial pathogenicity revisited.
Microbiology and molecular biology reviews : MMBR 1997;61(2):136-69.
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1997: Wilson D R; Wirtz R A; Finlay B B
Recognition of phage-expressed peptides containing Asx-Pro sequences by monoclonal antibodies produced against Plasmodium falciparum circumsporozoite protein.
Protein engineering 1997;10(5):531-40.
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1997: Wilson D R; Finlay B B
The 'Asx-Pro turn' as a local structural motif stabilized by alternative patterns of hydrogen bonds and a consensus-derived model of the sequence Asn-Pro-Asn.
Protein engineering 1997;10(5):519-29.
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1997: Finlay B B; Cossart P
Exploitation of mammalian host cell functions by bacterial pathogens.
Science (New York, N.Y.) 1997;276(5313):718-25.
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1997: Garcia-del Portillo F; Stein M A; Finlay B B
Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell.
Infection and immunity 1997;65(1):24-34.
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1996: Stein M; Kenny B; Stein M A; Finlay B B
Characterization of EspC, a 110-kilodalton protein secreted by enteropathogenic Escherichia coli which is homologous to members of the immunoglobulin A protease-like family of secreted proteins.
Journal of bacteriology 1996;178(22):6546-54.
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1996: Stein M A; Mathers D A; Yan H; Baimbridge K G; Finlay B B
Enteropathogenic Escherichia coli markedly decreases the resting membrane potential of Caco-2 and HeLa human epithelial cells.
Infection and immunity 1996;64(11):4820-5.
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1996: Finlay B B; Ruschkowski S; Kenny B; Stein M; Reinscheid D J; Stein M A; Rosenshine I
Enteropathogenic E. coli exploitation of host epithelial cells.
Annals of the New York Academy of Sciences 1996;797():26-31.
-
1996: Tang P; Rosenshine I; Cossart P; Finlay B B
Listeriolysin O activates mitogen-activated protein kinase in eucaryotic cells.
Infection and immunity 1996;64(6):2359-61.
-
1996: Rosenshine I; Ruschkowski S; Stein M; Reinscheid D J; Mills S D; Finlay B B
A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation.
The EMBO journal 1996;15(11):2613-24.
-
1996: Stein M A; Leung K Y; Zwick M; Garcia-del Portillo F; Finlay B B
Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells.
Molecular microbiology 1996;20(1):151-64.
-
1996: Kenny B; Lai L C; Finlay B B; Donnenberg M S
EspA, a protein secreted by enteropathogenic Escherichia coli, is required to induce signals in epithelial cells.
Molecular microbiology 1996;20(2):313-23.
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1996: Rosenshine I; Ruschkowski S; Finlay B B
Expression of attaching/effacing activity by enteropathogenic Escherichia coli depends on growth phase, temperature, and protein synthesis upon contact with epithelial cells.
Infection and immunity 1996;64(3):966-73.
-
1996: Siebers A; Finlay B B
M cells and the pathogenesis of mucosal and systemic infections.
Trends in microbiology 1996;4(1):22-9.
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1995: Garcia-del Portillo F; Finlay B B
The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments.
Trends in microbiology 1995;3(10):373-80.
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1995: Uitto V J; Pan Y M; Leung W K; Larjava H; Ellen R P; Finlay B B; McBride B C
Cytopathic effects of Treponema denticola chymotrypsin-like proteinase on migrating and stratified epithelial cells.
Infection and immunity 1995;63(9):3401-10.
-
1995: Kenny B; Finlay B B
Protein secretion by enteropathogenic Escherichia coli is essential for transducing signals to epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7991-5.
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1995: Siebers A; Finlay B B
Models to study enteropathogenic bacteria: lessons learned from Shigella.
Trends in microbiology 1995;3(6):207-9.
-
1995: Pucciarelli M G; Ruschkowski S; Trust T J; Finlay B B
Helicobacter pylori induces an increase in inositol phosphates in cultured epithelial cells.
FEMS microbiology letters 1995;129(2-3):293-9.
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1995: Garcia-del Portillo F; Finlay B B
Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors.
The Journal of cell biology 1995;129(1):81-97.
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1995: McCurry T E; Finlay B B
The Canadian Bacterial Diseases Network: a collaboration of universities, industry and government.
Trends in microbiology 1995;3(2):40-3.
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1994: Mills S D; Finlay B B
Comparison of Salmonella typhi and Salmonella typhimurium invasion, intracellular growth and localization in cultured human epithelial cells.
Microbial pathogenesis 1994;17(6):409-23.
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1994: Rosenshine I; Ruschkowski S; Foubister V; Finlay B B
Salmonella typhimurium invasion of epithelial cells: role of induced host cell tyrosine protein phosphorylation.
Infection and immunity 1994;62(11):4969-74.
-
1994: Garcia-del Portillo F; Finlay B B
Salmonella invasion of nonphagocytic cells induces formation of macropinosomes in the host cell.
Infection and immunity 1994;62(10):4641-5.
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1994: García-del Portillo F; Finlay B B
Invasion and intracellular proliferation of Salmonella within non-phagocytic cells.
Microbiología (Madrid, Spain) 1994;10(3):229-38.
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1994: Stein M A; Mills S D; Finlay B B
Salmonella: now you see it, now you don't.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(8):537-8.
-
1994: Foubister V; Rosenshine I; Donnenberg M S; Finlay B B
The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells.
Infection and immunity 1994;62(7):3038-40.
-
1994: Garcia-del Portillo F; Pucciarelli M G; Jefferies W A; Finlay B B
Salmonella typhimurium induces selective aggregation and internalization of host cell surface proteins during invasion of epithelial cells.
Journal of cell science 1994;107 ( Pt 7)():2005-20.
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1994: Tang P; Rosenshine I; Finlay B B
Listeria monocytogenes, an invasive bacterium, stimulates MAP kinase upon attachment to epithelial cells.
Molecular biology of the cell 1994;5(4):455-64.
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1994: Foubister V; Rosenshine I; Finlay B B
A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells.
The Journal of experimental medicine 1994;179(3):993-8.
-
1994: Rosenshine I; Ruschkowski S; Finlay B B
Inhibitors of cytoskeletal function and signal transduction to study bacterial invasion.
Methods in enzymology 1994;236():467-76.
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1994: Pucciarelli M G; Finlay B B
Polarized epithelial monolayers: model systems to study bacterial interactions with host epithelial cells.
Methods in enzymology 1994;236():438-47.
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1994: Finlay B B
Molecular and cellular mechanisms of Salmonella pathogenesis.
Current topics in microbiology and immunology 1994;192():163-85.
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1993: Garcia-del Portillo F; Zwick M B; Leung K Y; Finlay B B
Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10544-8.
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1993: Rosenshine I; Finlay B B
Salmonella's deceiving signals.
Journal of pediatric gastroenterology and nutrition 1993;17(4):453-4.
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1993: Garcia-del Portillo F; Foster J W; Finlay B B
Role of acid tolerance response genes in Salmonella typhimurium virulence.
Infection and immunity 1993;61(10):4489-92.
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1993: Garcia-del Portillo F; Zwick M B; Leung K Y; Finlay B B
Intracellular replication of Salmonella within epithelial cells is associated with filamentous structures containing lysosomal membrane glycoproteins.
Infectious agents and disease 1993;2(4):227-31.
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1993: Canil C; Rosenshine I; Ruschkowski S; Donnenberg M S; Kaper J B; Finlay B B
Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers.
Infection and immunity 1993;61(7):2755-62.
-
1993: Rosenshine I; Finlay B B
Exploitation of host signal transduction pathways and cytoskeletal functions by invasive bacteria.
BioEssays : news and reviews in molecular, cellular and developmental biology 1993;15(1):17-24.
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1992: Frey E A; Miller D S; Jahr T G; Sundan A; Bazil V; Espevik T; Finlay B B; Wright S D
Soluble CD14 participates in the response of cells to lipopolysaccharide.
The Journal of experimental medicine 1992;176(6):1665-71.
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1992: Garcia-del Portillo F; Foster J W; Maguire M E; Finlay B B
Characterization of the micro-environment of Salmonella typhimurium-containing vacuoles within MDCK epithelial cells.
Molecular microbiology 1992;6(22):3289-97.
-
1992: Rosenshine I; Donnenberg M S; Kaper J B; Finlay B B
Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake.
The EMBO journal 1992;11(10):3551-60.
-
1992: Leung K Y; Ruschkowski S R; Finlay B B
Isolation and characterization of the aadA aminoglycoside-resistance gene from Salmonella choleraesuis.
Molecular microbiology 1992;6(17):2453-60.
-
1992: Ruschkowski S; Rosenshine I; Finlay B B
Salmonella typhimurium induces an inositol phosphate flux in infected epithelial cells.
FEMS microbiology letters 1992;74(2-3):121-6.
-
1992: Betts J; Finlay B B
Identification of Salmonella typhimurium invasiveness loci.
Canadian journal of microbiology 1992;38(8):852-7.
-
1992: Finlay B B; Rosenshine I; Donnenberg M S; Kaper J B
Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells.
Infection and immunity 1992;60(6):2541-3.
-
1992: Rosenshine I; Duronio V; Finlay B B
Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells.
Infection and immunity 1992;60(6):2211-7.
-
1992: Patrick D; Betts J; Frey E A; Prameya R; Dorovini-Zis K; Finlay B B
Haemophilus influenzae lipopolysaccharide disrupts confluent monolayers of bovine brain endothelial cells via a serum-dependent cytotoxic pathway.
The Journal of infectious diseases 1992;165(5):865-72.
-
1991: Leung K Y; Finlay B B
Intracellular replication is essential for the virulence of Salmonella typhimurium.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11470-4.
-
1991: Finlay B B; Chatfield S; Leung K Y; Dougan G; Falkow S
Characterization of a Salmonella choleraesuis mutant that cannot multiply within epithelial cells.
Canadian journal of microbiology 1991;37(7):568-72.
-
1991: Finlay B B; Ruschkowski S; Dedhar S
Cytoskeletal rearrangements accompanying salmonella entry into epithelial cells.
Journal of cell science 1991;99 ( Pt 2)():283-96.
-
1990: Finlay B B; Falkow S
Salmonella interactions with polarized human intestinal Caco-2 epithelial cells.
The Journal of infectious diseases 1990;162(5):1096-106.
-
1990: Wilson D R; Chatfield S; Betts J; Griffiths A; Leung K Y; Dougan G; Finlay B B
Alternative methods of attenuating Salmonella species for potential vaccine use.
Research in microbiology 1990;141(7-8):827-30.
-
1989: Finlay B B; Falkow S
Salmonella as an intracellular parasite.
Molecular microbiology 1989;3(12):1833-41.
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