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Michael Fischbach

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Chemicals & Drugs

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Publications

TOP 3
Michael A Fischbach; Jeffrey A Bluestone; Wendell A Lim
Cell-based therapeutics: the next pillar of medicine.
Mohamed S Donia; Michael A Fischbach
Dyeing to learn more about the gut microbiota.
Christopher M Rath; Jiao Song; Justin L Sonnenburg; Theodore Alexandrov; Michael A Fischbach; Steven K Higginbottom; Marcos E Milla; Pieter C Dorrestein
Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations.

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All Publications

2013: Michael A Fischbach; Jeffrey A Bluestone; Wendell A Lim
Cell-based therapeutics: the next pillar of medicine.
Science translational medicine 2013;5(179):179ps7.
2013: Mohamed S Donia; Michael A Fischbach
Dyeing to learn more about the gut microbiota.
Cell host & microbe 2013;13(2):119-20.
2012: Christopher M Rath; Jiao Song; Justin L Sonnenburg; Theodore Alexandrov; Michael A Fischbach; Steven K Higginbottom; Marcos E Milla; Pieter C Dorrestein
Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations.
Analytical chemistry 2012;84(21):9259-67.
2011: Roland D Kersten; Bradley S Moore; Sang-Jip Nam; Yuquan Xu; Yu-Liang Yang; Peter Cimermancic; William Fenical; Michael A Fischbach; Pieter dorrestein
A mass spectrometry-guided genome mining approach for natural product peptidogenomics.
Nature chemical biology 2011;7(11):794-802.
2011: Michael A Fischbach; Justin L Sonnenburg
Eating for two: how metabolism establishes interspecies interactions in the gut.
Cell host & microbe 2011;10(4):336-47.
2011: Michael A Fischbach
Combination therapies for combating antimicrobial resistance.
Current opinion in microbiology 2011;14(5):519-23.
2010: Michael Zimmermann; Michael A Fischbach
A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureus.
Chemistry & biology 2010;17(9):925-30.
2010: Jessica Dawlaty; Xiaorong Zhang; Michael A Fischbach; Jon Clardy
Dapdiamides, tripeptide antibiotics formed by unconventional amide ligases.
Journal of natural products 2010;73(3):441-6.
2010: Christopher T Walsh; Michael A Fischbach
Natural products version 2.0: connecting genes to molecules.
Journal of the American Chemical Society 2010;132(8):2469-93.
2010: Michael A Fischbach; Nevan J Krogan
The next frontier of systems biology: higher-order and interspecies interactions.
Genome biology 2010;11(5):208.
2009: Jon Clardy; Michael A Fischbach; Cameron R Currie
The natural history of antibiotics.
Current biology : CB 2009;19(11):R437-41.
2009: Christopher T Walsh; Michael A Fischbach
Repurposing libraries of eukaryotic protein kinase inhibitors for antibiotic discovery.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1689-90.
2009: Daniel López; Michael A Fischbach; Frances Chu; Richard Losick; Roberto Kolter
Structurally diverse natural products that cause potassium leakage trigger multicellularity in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):280-5.
2008: Elizabeth S Sattely; Michael A Fischbach; Christopher T Walsh
Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways.
Natural product reports 2008;25(4):757-93.
2008: Michael A Fischbach; Christopher T Walsh; Jon Clardy
The evolution of gene collectives: How natural selection drives chemical innovation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4601-8.
2008: Christopher T Walsh; Michael A Fischbach
Inhibitors of sterol biosynthesis as Staphylococcus aureus antibiotics.
Angewandte Chemie (International ed. in English) 2008;47(31):5700-2.
2007: Elizabeth M Nolan; Michael A Fischbach; Alexander Koglin; Christopher T Walsh
Biosynthetic tailoring of microcin E492m: post-translational modification affords an antibacterial siderophore-peptide conjugate.
Journal of the American Chemical Society 2007;129(46):14336-47.
2007: Michael A Fischbach; Jonathan Lai; Eric D Roche; Christopher T Walsh; David R. Liu
Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):11951-6.
2007: Michael A Fischbach; Jon Clardy
One pathway, many products.
Nature chemical biology 2007;3(7):353-5.
2007: Rebecca A Butcher; Frank Schroeder; Michael A Fischbach; Paul D Straight; Roberto Kolter; Christopher T Walsh; Jon Clardy
The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(5):1506-9.
2007: Paul D Straight; Michael A Fischbach; Christopher T Walsh; David Z Rudner; Roberto Kolter
A singular enzymatic megacomplex from Bacillus subtilis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(1):305-10.
2006: Jon Clardy; Michael A Fischbach; Christopher T Walsh
New antibiotics from bacterial natural products.
Nature biotechnology 2006;24(12):1541-50.
2006: Michael A Fischbach; Hening Lin; Lu Zhou; Yang Yu; Rebecca J Abergel; David R. Liu; Kenneth N Raymond; Barry L Wanner; Roland K Strong; Christopher T Walsh; Alan Aderem; Kelly D Smith
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16502-7.
2006: Michael A Fischbach; Christopher T Walsh
Biochemistry. Directing biosynthesis.
Science (New York, N.Y.) 2006;314(5799):603-5.
2006: Jonathan Lai; Michael A Fischbach; David R. Liu; Christopher T Walsh
Localized protein interaction surfaces on the EntB carrier protein revealed by combinatorial mutagenesis and selection.
Journal of the American Chemical Society 2006;128(34):11002-3.
2006: Nicholas A Larsen; H Lin; R Wei; Michael A Fischbach; Christopher T Walsh
Structural characterization of enterobactin hydrolase IroE.
Biochemistry 2006;45(34):10184-90.
2006: Mi Jin; Michael A Fischbach; Jon Clardy
A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid.
Journal of the American Chemical Society 2006;128(33):10660-1.
2006: Michael A Fischbach; Christopher T Walsh
Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.
Chemical reviews 2006;106(8):3468-96.
2006: Hening Lin; Michael A Fischbach; Gregory J Gatto; David R. Liu; Christopher T Walsh
Bromoenterobactins as potent inhibitors of a pathogen-associated, siderophore-modifying C-glycosyltransferase.
Journal of the American Chemical Society 2006;128(29):9324-5.
2006: Jonathan Lai; Michael A Fischbach; David R. Liu; Christopher T Walsh
A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(14):5314-9.
2006: Michael A Fischbach; Hening Lin; David R. Liu; Christopher T Walsh
How pathogenic bacteria evade mammalian sabotage in the battle for iron.
Nature chemical biology 2006;2(3):132-8.
2006: Minkui Luo; Hening Lin; Michael A Fischbach; David R. Liu; Christopher T Walsh; John T Groves
Enzymatic tailoring of enterobactin alters membrane partitioning and iron acquisition.
ACS chemical biology 2006;1(1):29-32.
2006: Pieter dorrestein; Jonathan Blackhall; Paul D Straight; Michael A Fischbach; Sylvie Garneau-Tsodikova; Daniel J Edwards; Shaun McLaughlin; Myat Lin; William H Gerwick; Roberto Kolter; Christopher T Walsh; Neil L Kelleher
Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry.
Biochemistry 2006;45(6):1537-46.
2006: Piotr Garstecki; Michael J Fuerstman; Michael A Fischbach; Samuel K Sia; George M Whitesides
Mixing with bubbles: a practical technology for use with portable microfluidic devices.
Lab on a chip 2006;6(2):207-12.
2005: Hening Lin; Michael A Fischbach; David R. Liu; Christopher T Walsh
In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes.
Journal of the American Chemical Society 2005;127(31):11075-84.
2005: Michael A Fischbach; Hening Lin; David R. Liu; Christopher T Walsh
In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):571-6.
2004: Daniel B Wolfe; Richard S Conroy; Piotr Garstecki; Brian T Mayers; Michael A Fischbach; Kateri E Paul; Mara Prentiss; George M Whitesides
Dynamic control of liquid-core/liquid-cladding optical waveguides.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12434-8.