Jorge Fischbarg

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Montalbetti Nicolás; Fischbarg Jorge
Frequency spectrum of transepithelial potential difference reveals transport-related oscillations.
Diecke Friedrich P J; Ma Li; Iserovich Pavel; Fischbarg Jorge
Corneal endothelium transports fluid in the absence of net solute transport.
Ma Li; Kuang Kunyan; Smith Randall W; Rittenband David; Iserovich Pavel; Diecke F P J; Fischbarg Jorge
Modulation of tight junction properties relevant to fluid transport across rabbit corneal endothelium.

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All Publications

2009: Montalbetti Nicolás; Fischbarg Jorge
Frequency spectrum of transepithelial potential difference reveals transport-related oscillations.
Biophysical journal 2009;97(6):1530-7.
2007: Diecke Friedrich P J; Ma Li; Iserovich Pavel; Fischbarg Jorge
Corneal endothelium transports fluid in the absence of net solute transport.
Biochimica et biophysica acta 2007;1768(9):2043-8.
2007: Ma Li; Kuang Kunyan; Smith Randall W; Rittenband David; Iserovich Pavel; Diecke F P J; Fischbarg Jorge
Modulation of tight junction properties relevant to fluid transport across rabbit corneal endothelium.
Experimental eye research 2007;84(4):790-8.
2006: Kuang Kunyan; Yiming Maimiti; Zhu Zhaorong; Iserovich Pavel; Diecke Friedrich P; Fischbarg Jorge
Lack of threshold for anisotonic cell volume regulation.
The Journal of membrane biology 2006;211(1):27-33.
2006: Fischbarg J; Diecke F P J; Iserovich P; Rubashkin A
The Role of the Tight Junction in Paracellular Fluid Transport across Corneal Endothelium. Electro-osmosis as a Driving Force.
The Journal of membrane biology 2006;210(2):117-30.
2006: Fischbarg J
Aquaporins and fluid transport: an evolving relationship.
Cellular and molecular biology (Noisy-le-Grand, France) 2006;52(7):28-33.
2005: Rubashkin A; Iserovich P; Hernández J A; Fischbarg J
Epithelial fluid transport: protruding macromolecules and space charges can bring about electro-osmotic coupling at the tight junctions.
The Journal of membrane biology 2005;208(3):251-63.
2005: Manolescu Andrei; Salas-Burgos Alexis M; Fischbarg Jorge; Cheeseman Chris I
Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7).
The Journal of biological chemistry 2005;280(52):42978-83.
2005: Klepper Jörg; Salas-Burgos Alexis; Gertsen Elena; Fischbarg Jorge
Bench meets bedside: a 10-year-old girl and amino acid residue glycine 75 of the facilitative glucose transporter GLUT1.
Biochemistry 2005;44(38):12621-6.
2005: Uhlemann Anne-Catrin; Cameron Angus; Eckstein-Ludwig Ursula; Fischbarg Jorge; Iserovich Pavel; Zuniga Felipe A; East Malcolm; Lee Anthony; Brady Leo; Haynes Richard K; Krishna Sanjeev
A single amino acid residue can determine the sensitivity of SERCAs to artemisinins.
Nature structural & molecular biology 2005;12(7):628-9.
2005: Diecke Friedrich P; Wen Quan; Iserovich Pavel; Li Jianfeng; Kuang Kunyan; Fischbarg Jorge
Regulation of Na-K-2Cl cotransport in cultured bovine corneal endothelial cells.
Experimental eye research 2005;80(6):777-85.
2005: Fischbarg J; Diecke F P J
A mathematical model of electrolyte and fluid transport across corneal endothelium.
The Journal of membrane biology 2005;203(1):41-56.
2005: Rodríguez Patricio; Rivas Coralia I; Godoy Alejandro; Villanueva Marcela; Fischbarg Jorge; Vera Juan Carlos; Reyes Alejandro M
Redefining the facilitated transport of mannose in human cells: absence of a glucose-insensitive, high-affinity facilitated mannose transport system.
Biochemistry 2005;44(1):313-20.
2004: Salas-Burgos Alexis; Iserovich Pavel; Zuniga Felipe; Vera Juan Carlos; Fischbarg Jorge
Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecules.
Biophysical journal 2004;87(5):2990-9.
2004: Kuang Kunyan; Li Yansui; Yiming Maimaiti; Sánchez José M; Iserovich Pavel; Cragoe E J; Diecke Friedrich P J; Fischbarg Jorge
Intracellular [Na+], Na+ pathways, and fluid transport in cultured bovine corneal endothelial cells.
Experimental eye research 2004;79(1):93-103.
2004: Diecke Friedrich P J; Wen Quan; Sanchez Jose M; Kuang Kunyan; Fischbarg Jorge
Immunocytochemical localization of Na+-HCO3- cotransporters and carbonic anhydrase dependence of fluid transport in corneal endothelial cells.
American journal of physiology. Cell physiology 2004;286(6):C1434-42.
2004: Kuang Kunyan; Yiming Maimaiti; Wen Quan; Li Yansui; Ma Li; Iserovich Pavel; Verkman A S; Fischbarg Jorge
Fluid transport across cultured layers of corneal endothelium from aquaporin-1 null mice.
Experimental eye research 2004;78(4):791-8.
2004: Fischbarg Jorge; Maurice David M
An update on corneal hydration control.
Experimental eye research 2004;78(3):537-41.
2003: Wang Dong; Pascual Juan M; Iserovich Pavel; Yang Hong; Ma Li; Kuang Kunyan; Zuniga Felipe A; Sun Ruo Peng; Swaroop Kavita M; Fischbarg Jorge; De Vivo Darryl C
Functional studies of threonine 310 mutations in Glut1: T310I is pathogenic, causing Glut1 deficiency.
The Journal of biological chemistry 2003;278(49):49015-21.
2003: Fischbarg Jorge
Diquafosol tetrasodium. Inspire/Allergan/Santen.
Current opinion in investigational drugs (London, England : 2000) 2003;4(11):1377-83.
2003: Fischbarg Jorge
On the mechanism of fluid transport across corneal endothelium and epithelia in general.
Journal of experimental zoology. Part A, Comparative experimental biology 2003;300(1):30-40.
2003: Joët T; Morin C; Fischbarg J; Louw Abraham I; Eckstein-Ludwig U; Woodrow C; Krishna S
Why is the Plasmodium falciparum hexose transporter a promising new drug target?
Expert opinion on therapeutic targets 2003;7(5):593-602.
2003: Klepper Jörg; Flörcken Anne; Fischbarg Jorge; Voit Thomas
Effects of anticonvulsants on GLUT1-mediated glucose transport in GLUT1 deficiency syndrome in vitro.
European journal of pediatrics 2003;162(2):84-9.
2002: Manning Suzanne K; Woodrow Charles; Zuniga Felipe A; Iserovich Pavel; Fischbarg Jorge; Louw Abraham I; Krishna Sanjeev
Mutational analysis of the hexose transporter of Plasmodium falciparum and development of a three-dimensional model.
The Journal of biological chemistry 2002;277(34):30942-9.
2002: Iserovich Pavel; Wang Dong; Ma Li; Yang Hong; Zuniga Felipe A; Pascual Juan M; Kuang Kunyan; De Vivo Darryl C; Fischbarg Jorge
Changes in glucose transport and water permeability resulting from the T310I pathogenic mutation in Glut1 are consistent with two transport channels per monomer.
The Journal of biological chemistry 2002;277(34):30991-7.
2002: Reyes Alejandro M; Bustamante Fernando; Rivas Coralia I; Ortega Marcela; Donnet Claudia; Rossi Juan P; Fischbarg Jorge; Vera Juan Carlos
Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1.
Biochemistry 2002;41(25):8075-81.
2002: Sánchez J M; Li Y; Rubashkin A; Iserovich P; Wen Q; Ruberti J W; Smith R W; Rittenband D; Kuang K; Diecke F P J; Fischbarg J
Evidence for a central role for electro-osmosis in fluid transport by corneal endothelium.
The Journal of membrane biology 2002;187(1):37-50.
2002: Iserovich Pavel; Yiming Maimaiti; Wang Zheng; Bildin Victor N; Reinach Peter S; Fischbarg Jorge
Epidermal growth factor stimulates fluid transport in SV40 transformed rabbit lacrimal gland cells.
Advances in experimental medicine and biology 2002;506(Pt A):243-7.
2001: Bildin V N; Iserovich P; Fischbarg J; Reinach P S
Differential expression of Na:K:2Cl cotransporter, glucose transporter 1, and aquaporin 1 in freshly isolated and cultured bovine corneal tissues.
Experimental biology and medicine (Maywood, N.J.) 2001;226(10):919-26.
2001: Zuniga F A; Shi G; Haller J F; Rubashkin A; Flynn D R; Iserovich P; Fischbarg J
A three-dimensional model of the human facilitative glucose transporter Glut1.
The Journal of biological chemistry 2001;276(48):44970-5.
2001: Brockmann K; Wang D; Korenke C G; von Moers A; Ho Y Y; Pascual J M; Kuang K; Yang H; Ma L; Kranz-Eble P; Fischbarg J; Hanefeld F; De Vivo D C
Autosomal dominant glut-1 deficiency syndrome and familial epilepsy.
Annals of neurology 2001;50(4):476-85.
2001: Patil R V; Han Z; Yiming M; Yang J; Iserovich P; Wax M B; Fischbarg J
Fluid transport by human nonpigmented ciliary epithelial layers in culture: a homeostatic role for aquaporin-1.
American journal of physiology. Cell physiology 2001;281(4):C1139-45.
2001: Ho Y Y; Yang H; Klepper J; Fischbarg J; Wang D; De Vivo D C
Glucose transporter type 1 deficiency syndrome (Glut1DS): methylxanthines potentiate GLUT1 haploinsufficiency in vitro.
Pediatric research 2001;50(2):254-60.
2001: Kuang K; Haller J F; Shi G; Kang F; Cheung M; Iserovich P; Fischbarg J
Mercurial sensitivity of aquaporin 1 endofacial loop B residues.
Protein science : a publication of the Protein Society 2001;10(8):1627-34.
2001: Li Y; Kuang K; Yerxa B; Wen Q; Rosskothen H; Fischbarg J
Rabbit conjunctival epithelium transports fluid, and P2Y2(2) receptor agonists stimulate Cl(-) and fluid secretion.
American journal of physiology. Cell physiology 2001;281(2):C595-602.
2001: Wen Q; Diecke F P; Iserovich P; Kuang K; Sparrow J; Fischbarg J
Immunocytochemical localization of aquaporin-1 in bovine corneal endothelial cells and keratocytes.
Experimental biology and medicine (Maywood, N.J.) 2001;226(5):463-7.
2001: Kuang K; Li Y; Wen Q; Wang Z; Li J; Yang Y; Iserovich P; Reinach P S; Sparrow J; Diecke F P; Fischbarg J
Corneal endothelial NKCC: molecular identification, location, and contribution to fluid transport.
American journal of physiology. Cell physiology 2001;280(3):C491-9.
2000: Kang F; Kunyan K; Fischbarg J
[Cultured bovine corneal epithelial cells express functional water channel]
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 2000;36(5):381-3.
2000: Bildin V N; Yang H; Crook R B; Fischbarg J; Reinach P S
Adaptation by corneal epithelial cells to chronic hypertonic stress depends on upregulation of Na:K:2Cl cotransporter gene and protein expression and ion transport activity.
The Journal of membrane biology 2000;177(1):41-50.
2000: Yang H; Reinach P S; Koniarek J P; Wang Z; Iserovich P; Fischbarg J
Fluid transport by cultured corneal epithelial cell layers.
The British journal of ophthalmology 2000;84(2):199-204.
1999: Klepper J; Fischbarg J; Vera J C; Wang D; De Vivo D C
GLUT1-deficiency: barbiturates potentiate haploinsufficiency in vitro.
Pediatric research 1999;46(6):677-83.
1999: Hara E; Reinach P S; Wen Q; Iserovich P; Fischbarg J
Fluoxetine inhibits K(+) transport pathways (K(+) efflux, Na(+)-K(+)-2Cl(-) cotransport, and Na(+) pump) underlying volume regulation in corneal endothelial cells.
The Journal of membrane biology 1999;171(1):75-85.
1999: Li J; Kuang K; Nielsen S; Fischbarg J
Molecular identification and immunolocalization of the water channel protein aquaporin 1 in CBCECs.
Investigative ophthalmology & visual science 1999;40(6):1288-92.
1999: Klepper J; Wang D; Fischbarg J; Vera J C; Jarjour I T; O'Driscoll K R; De Vivo D C
Defective glucose transport across brain tissue barriers: a newly recognized neurological syndrome.
Neurochemical research 1999;24(4):587-94.
1999: Fischbarg J; Diecke F P; Kuang K; Yu B; Kang F; Iserovich P; Li Y; Rosskothen H; Koniarek J P
Transport of fluid by lens epithelium.
The American journal of physiology 1999;276(3 Pt 1):C548-57.
1999: Kang F; Kuang K; Li J; Fischbarg J
Cultured bovine corneal epithelial cells express a functional aquaporin water channel.
Investigative ophthalmology & visual science 1999;40(1):253-7.
1998: Kang F; Serdarevic O N; Kuang K; Li J; Zhu Z; Fischbarg J
Effects of ciprofloxacin, streptomycin, and gentamicin on rabbit corneal transendothelial electrical potential difference.
Cornea 1998;17(2):185-90.
1998: Diecke F P; Zhu Z; Kang F; Kuang K; Fischbarg J
Sodium, potassium, two chloride cotransport in corneal endothelium: characterization and possible role in volume regulation and fluid transport.
Investigative ophthalmology & visual science 1998;39(1):104-10.
1998: Iserovich P; Reinach P S; Yang H; Fischbarg J
A novel approach to resolve cellular volume responses to an anisotonic challenge.
Advances in experimental medicine and biology 1998;438():687-92.
1998: Bildin V N; Yang H; Fischbarg J; Reinach P S
Effects of chronic hypertonic stress on regulatory volume increase and Na-K-2Cl cotransporter expression in cultured corneal epithelial cells.
Advances in experimental medicine and biology 1998;438():637-42.
1997: Iserovich P; Kuang K; Chun T; Fischbarg J
A novel method to determine the diffusional water permeability of oocyte plasma membranes.
Biology of the cell / under the auspices of the European Cell Biology Organization 1997;89(5-6):293-7.
1997: Schubert H D; Kuang K; Kang F; Head M W; Fischbarg J
Macular holes: migratory gaps and vitreous as obstacles to glial closure.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(8):523-9.
1997: Wu X; Yang H; Iserovich P; Fischbarg J; Reinach P S
Regulatory volume decrease by SV40-transformed rabbit corneal epithelial cells requires ryanodine-sensitive Ca2+-induced Ca2+ release.
The Journal of membrane biology 1997;158(2):127-36.
1997: Akiyama R; Kuang K; Chiaradía P A; Roberts C W; Fischbarg J
Effects of acetylcholine, carbachol, and mannitol on rabbit corneal endothelial function as assessed by corneal deturgescence.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(6):384-7.
1997: Akiyama R; Kuang K; Koniarek J P; Chiaradía P A; Roberts C W; Fischbarg J
Solutions containing miotic agents: effects on corneal transendothelial electrical potential difference.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(6):379-83.
1997: Fischbarg J; Kuang K; Li J; Iserovich P; Wen Q
Aquaporins and ion conductance.
Science (New York, N.Y.) 1997;275(5305):1491-2; author reply 1492.
1997: Fischbarg J
Mechanism of fluid transport across corneal endothelium and other epithelial layers: a possible explanation based on cyclic cell volume regulatory changes.
The British journal of ophthalmology 1997;81(1):85-9.
1996: Loike J D; Hickman S; Kuang K; Xu M; Cao L; Vera J C; Silverstein S C; Fischbarg J
Sodium-glucose cotransporters display sodium- and phlorizin-dependent water permeability.
The American journal of physiology 1996;271(5 Pt 1):C1774-9.
1996: Zhu Z; Kuang K; Kang F; Li J; Fischbarg J
Platelet activating factor inhibits fluid transport by corneal endothelium.
Investigative ophthalmology & visual science 1996;37(9):1899-906.
1995: Fischbarg J; Vera J C
Multifunctional transporter models: lessons from the transport of water, sugars, and ring compounds by GLUTs.
The American journal of physiology 1995;268(5 Pt 1):C1077-89.
1995: Fischbarg J
A rapidly emerging field: water channel proteins in the eye.
Investigative ophthalmology & visual science 1995;36(5):758-63.
1995: Fischbarg J; Li J; Cheung M; Czegledy F; Iserovich P; Kuang K
Predictive evidence for a porin-type beta-barrel fold in CHIP28 and other members of the MIP family. A restricted-pore model common to water channels and facilitators.
The Journal of membrane biology 1995;143(3):177-88.
1994: Fischbarg J; Cheung M; Li J; Iserovich P; Czegledy F; Kuang K; Garner M
Are most transporters and channels beta barrels?
Molecular and cellular biochemistry 1994;140(2):147-62.
1993: Fischbarg J; Cheung M; Czegledy F; Li J; Iserovich P; Kuang K; Hubbard J; Garner M; Rosen O M; Golde D W
Evidence that facilitative glucose transporters may fold as beta-barrels.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11658-62.
1993: Loike J D; Cao L; Kuang K; Vera J C; Silverstein S C; Fischbarg J
Role of facilitative glucose transporters in diffusional water permeability through J774 cells.
The Journal of general physiology 1993;102(5):897-906.
1993: Fischbarg J; Li J; Kuang K; Echevarría M; Iserovich P
Determination of volume and water permeability of plated cells from measurements of light scattering.
The American journal of physiology 1993;265(5 Pt 1):C1412-23.
1993: Echevarría M; Kuang K; Iserovich P; Li J; Preston G M; Agre P; Fischbarg J
Cultured bovine corneal endothelial cells express CHIP28 water channels.
The American journal of physiology 1993;265(5 Pt 1):C1349-55.
1993: Schubert H D; Kuang K; Fischbarg J
Postvitrectomy hypotonia: the role of the vitreous and retinochoroidal lesions.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1993;231(6):359-64.
1993: Echevarria M; Frindt G; Preston G M; Milovanovic S; Agre P; Fischbarg J; Windhager E E
Expression of multiple water channel activities in Xenopus oocytes injected with mRNA from rat kidney.
The Journal of general physiology 1993;101(6):827-41.
1993: Li J; Akiyama R; Kuang K; Fischbarg J
Effects of BSS and BSS+ irrigation solutions on rabbit corneal transendothelial electrical potential difference.
Cornea 1993;12(3):199-203.
1992: Narula P; Xu M; Kuang K Y; Akiyama R; Fischbarg J
Fluid transport across cultured bovine corneal endothelial cell monolayers.
The American journal of physiology 1992;262(1 Pt 1):C98-103.
1990: Akiyama R; Koniarek J P; Fischbarg J
Effect of fluorescein on the electrical potential difference across isolated rabbit corneal endothelium.
Investigative ophthalmology & visual science 1990;31(12):2593-5.
1990: Kuang K Y; Xu M; Koniarek J P; Fischbarg J
Effects of ambient bicarbonate, phosphate and carbonic anhydrase inhibitors on fluid transport across rabbit corneal endothelium.
Experimental eye research 1990;50(5):487-93.
1990: Fischbarg J; Kuang K Y; Vera J C; Arant S; Silverstein S C; Loike J; Rosen O M
Glucose transporters serve as water channels.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):3244-7.
1989: Fischbarg J; Kuang K Y; Hirsch J; Lecuona S; Rogozinski L; Silverstein S C; Loike J
Evidence that the glucose transporter serves as a water channel in J774 macrophages.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8397-401.
1989: Luckett P M; Fischbarg J; Bhattacharya J; Silverstein S C
Hydraulic conductivity of endothelial cell monolayers cultured on human amnion.
The American journal of physiology 1989;256(6 Pt 2):H1675-83.
1989: Hernandez J; Fischbarg J; Liebovitch L S
Kinetic model of the effects of electrogenic enzymes on the membrane potential.
Journal of theoretical biology 1989;137(1):113-25.
1988: Fischbarg J
On the possible permeation of water across the glucose transporter.
Molecular and cellular biochemistry 1988;82(1-2):107-11.
1988: Huang A J; Furie M B; Nicholson S C; Fischbarg J; Liebovitch L S; Silverstein S C
Effects of human neutrophil chemotaxis across human endothelial cell monolayers on the permeability of these monolayers to ions and macromolecules.
Journal of cellular physiology 1988;135(3):355-66.
1988: Koniarek J P; Lee H B; Rosskothen H D; Liebovitch L S; Fischbarg J
Use of transendothelial electrical potential difference to assess the chondroitin sulfate effect in corneal preservation media.
Investigative ophthalmology & visual science 1988;29(4):657-60.
1987: Fischbarg J; Liebovitch L S; Koniarek J P
Inhibition of transepithelial osmotic water flow by blockers of the glucose transporter.
Biochimica et biophysica acta 1987;898(3):266-74.
1987: Liebovitch L S; Fischbarg J; Koniarek J P; Todorova I; Wang M
Fractal model of ion-channel kinetics.
Biochimica et biophysica acta 1987;896(2):173-80.
1986: Liebovitch L S; Fischbarg J
Membrane pores: a computer simulation of interacting pores analyzed by g1(tau) and g2(tau) correlation functions.
Journal of theoretical biology 1986;119(3):287-97.
1985: Fischbarg J; Hernandez J; Liebovitch L S; Koniarek J P
The mechanism of fluid and electrolyte transport across corneal endothelium: critical revision and update of a model.
Current eye research 1985;4(4):351-60.
1985: Liebovitch L S; Fischbarg J
Determining the kinetics of membrane pores from patch clamp data without measuring the open and closed times.
Biochimica et biophysica acta 1985;813(1):132-6.
1985: Fischbarg J; Liebovitch L S; Koniarek J P
A central role for cell osmolarity in isotonic fluid transport across epithelia.
Biology of the cell / under the auspices of the European Cell Biology Organization 1985;55(3):239-44.
1984: Fischbarg J; Lim J J
Fluid and electrolyte transports across corneal endothelium.
Current topics in eye research 1984;4():201-23.
1983: Lim J J; Liebovitch L S; Fischbarg J
Ionic selectivity of the paracellular shunt path across rabbit corneal endothelium.
The Journal of membrane biology 1983;73(1):95-102.
1982: Liebovitch L S; Fischbarg J
Effects of inhibitors of passive Na+ and HCO3- fluxes on electrical potential and fluid transport across rabbit corneal endothelium.
Current eye research 1982;2(3):183-6.
1981: Lim J J; Fischbarg J
Electrical properties of rabbit corneal endothelium as determined from impedance measurements.
Biophysical journal 1981;36(3):677-95.
1981: Liebovitch L S; Fischbarg J; Koatz R
Osmotic water permeability of rabbit corneal endothelium and its dependence on ambient concentration.
Biochimica et biophysica acta 1981;646(1):71-6.

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Jorge Fischbarg

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